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Gene: USP47 (ubiquitin specific peptidase 47) Homo sapiens
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Symbol: USP47
Name: ubiquitin specific peptidase 47
Description: Exhibits WD40-repeat domain binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of nitrogen compound metabolic process; and positive regulation of canonical Wnt signaling pathway. Localizes to SCF ubiquitin ligase complex and cytoplasm; INTERACTS WITH aflatoxin B1; antirheumatic drug; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deubiquitinating enzyme 47; DKFZp686C13257; FLJ20727; Trf (TATA binding protein-related factor)-proximal homolog; TRFP; ubiquitin carboxyl-terminal hydrolase 47; ubiquitin specific protease 47; ubiquitin thioesterase 47; ubiquitin thiolesterase 47; ubiquitin-specific-processing protease 47
Orthologs:
Mus musculus (house mouse) : Usp47 (ubiquitin specific peptidase 47)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp47 (ubiquitin specific peptidase 47)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp47 (ubiquitin specific peptidase 47)
Pan paniscus (bonobo/pygmy chimpanzee) : USP47 (ubiquitin specific peptidase 47)
Canis lupus familiaris (dog) : USP47 (ubiquitin specific peptidase 47)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp47 (ubiquitin specific peptidase 47)
Sus scrofa (pig) : USP47 (ubiquitin specific peptidase 47)
Chlorocebus sabaeus (African green monkey) : USP47 (ubiquitin specific peptidase 47)
Heterocephalus glaber (naked mole-rat) : Usp47 (ubiquitin specific peptidase 47)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1111,841,423 - 11,961,887 (+)EnsemblGRCh38hg38GRCh38
GRCh381111,841,972 - 11,961,887 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371111,862,970 - 11,980,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,819,546 - 11,937,448 (+)NCBINCBI36hg18NCBI36
Build 341111,820,140 - 11,934,691NCBI
Celera1111,987,161 - 12,106,131 (+)NCBI
Cytogenetic Map11p15.3NCBI
HuRef1111,538,966 - 11,656,900 (+)NCBIHuRef
CHM1_11111,862,028 - 11,979,798 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on USP47
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321301
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.