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Gene: ARPC1B (actin related protein 2/3 complex subunit 1B) Homo sapiens
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Symbol: ARPC1B
Name: actin related protein 2/3 complex subunit 1B
Description: A structural constituent of cytoskeleton. Contributes to actin filament binding activity. Involved in Arp2/3 complex-mediated actin nucleation. Localizes to Arp2/3 protein complex. Implicated in gastritis and myelodysplastic syndrome. Biomarker of oral squamous cell carcinoma; schizophrenia; and stomach cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: actin related protein 2/3 complex subunit 1B, 41kDa; actin related protein 2/3 complex, subunit 1b; actin related protein 2/3 complex, subunit 1B, 41kDa; actin-related protein 2/3 complex subunit 1B; ARC41; arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; p40-ARC; p41-ARC; PLTEID
Orthologs:
Mus musculus (house mouse) : Arpc1b (actin related protein 2/3 complex, subunit 1B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arpc1b (actin related protein 2/3 complex, subunit 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arpc1b (actin related protein 2/3 complex subunit 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : ARPC1B (actin related protein 2/3 complex subunit 1B)
Canis lupus familiaris (dog) : ARPC1B (actin related protein 2/3 complex subunit 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arpc1b (actin related protein 2/3 complex subunit 1B)
Sus scrofa (pig) : ARPC1B (actin related protein 2/3 complex subunit 1B)
Heterocephalus glaber (naked mole-rat) : Arpc1b (actin related protein 2/3 complex subunit 1B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl799,374,249 - 99,394,816 (+)EnsemblGRCh38hg38GRCh38
GRCh38799,374,254 - 99,394,816 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37798,972,298 - 99,004,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36798,810,265 - 98,830,360 (+)NCBINCBI36hg18NCBI36
Build 34798,616,979 - 98,637,053NCBI
Celera793,706,528 - 93,726,623 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef793,608,035 - 93,628,135 (+)NCBIHuRef
CHM1_1798,902,377 - 98,922,501 (+)NCBICHM1_1
CRA_TCAGchr7v2798,332,071 - 98,352,197 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARPC1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736395
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.