ACOT2 (acyl-CoA thioesterase 2) - Rat Genome Database

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Gene: ACOT2 (acyl-CoA thioesterase 2) Homo sapiens
Analyze
Symbol: ACOT2
Name: acyl-CoA thioesterase 2
RGD ID: 1605691
HGNC Page HGNC:18431
Description: Enables fatty acyl-CoA hydrolase activity. Involved in acyl-CoA metabolic process; long-chain fatty acid metabolic process; and very long-chain fatty acid metabolic process. Located in mitochondrion.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: acyl-coenzyme A thioester hydrolase 2a; acyl-coenzyme A thioesterase 2, mitochondrial; CTE-IA; CTE1A; long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; mitochondrial acyl-CoA thioesterase 2; MTE1; peroxisomal long-chain acyl-coA thioesterase 2; PTE2; PTE2A; ZAP128
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,567,620 - 73,575,658 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,567,620 - 73,575,658 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,034,324 - 74,042,362 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,105,525 - 73,112,112 (+)NCBINCBI36Build 36hg18NCBI36
Celera1454,071,870 - 54,078,454 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,202,099 - 54,210,141 (+)NCBIHuRef
CHM1_11473,973,914 - 73,981,955 (+)NCBICHM1_1
T2T-CHM13v2.01467,775,130 - 67,783,167 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,3-dinitrobenzene  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
Acetyl tributyl citrate  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
amiodarone  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (EXP)
azoxystrobin  (ISO)
benzatropine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (ISO)
CGP 52608  (EXP)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
ciprofibrate  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
clozapine  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (EXP)
corn oil  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
Diosbulbin B  (ISO)
diquat  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
finasteride  (ISO)
flavonoids  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gemfibrozil  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
GW 6471  (ISO)
hydralazine  (EXP)
imidacloprid  (ISO)
indole-3-methanol  (ISO)
inulin  (ISO)
isotretinoin  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
manganese(II) chloride  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
mitomycin C  (EXP)
monosodium L-glutamate  (ISO)
Muraglitazar  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel sulfate  (EXP)
nimesulide  (ISO)
oxybenzone  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorobutanesulfonic acid  (EXP)
perfluorodecanoic acid  (EXP)
perfluorododecanoic acid  (EXP,ISO)
perfluoroheptanoic acid  (EXP)
perfluorohexanesulfonic acid  (EXP,ISO)
perfluorohexanoic acid  (EXP)
perfluorononanoic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanesulfonamide  (EXP)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (EXP)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phenol  (EXP)
phenylephrine  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-1,2-dichloropropane  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (EXP)
senecionine  (ISO)
sinapic acid  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
streptozocin  (ISO)
sulfluramid  (EXP)
sulforaphane  (ISO)
Tesaglitazar  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thiabendazole  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
toluene  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
troglitazone  (ISO)
urethane  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vitamin E  (EXP)
zaragozic acid A  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart. King KL, etal., J Lipid Res. 2007 Jul;48(7):1511-7. Epub 2007 Apr 16.
2. The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment. Liang Y, etal., Metabolism. 2006 Oct;55(10):1411-9.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Evidence for mitochondrial thioesterase 1 as a peroxisome proliferator-activated receptor-alpha-regulated gene in cardiac and skeletal muscle. Stavinoha MA, etal., Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E888-95. Epub 2004 Aug 3.
Additional References at PubMed
PMID:7596406   PMID:8125298   PMID:10944470   PMID:12477932   PMID:12665801   PMID:14702039   PMID:15007068   PMID:15489334   PMID:16103133   PMID:16940157   PMID:17353931   PMID:18407958  
PMID:19497300   PMID:20178365   PMID:20379614   PMID:20877624   PMID:21873635   PMID:23376485   PMID:25281560   PMID:25464930   PMID:26186194   PMID:28514442   PMID:29395067   PMID:29568061  
PMID:30021884   PMID:31617661   PMID:31871319   PMID:32877691   PMID:33001583   PMID:33961781   PMID:34079125   PMID:34800366   PMID:35215835   PMID:35384245   PMID:35545034   PMID:36193167  
PMID:36215168   PMID:37704626   PMID:38334954   PMID:38569033  


Genomics

Comparative Map Data
ACOT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,567,620 - 73,575,658 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,567,620 - 73,575,658 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,034,324 - 74,042,362 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,105,525 - 73,112,112 (+)NCBINCBI36Build 36hg18NCBI36
Celera1454,071,870 - 54,078,454 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,202,099 - 54,210,141 (+)NCBIHuRef
CHM1_11473,973,914 - 73,981,955 (+)NCBICHM1_1
T2T-CHM13v2.01467,775,130 - 67,783,167 (+)NCBIT2T-CHM13v2.0
Acot2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,034,635 - 84,040,651 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,034,635 - 84,040,647 (+)EnsemblGRCm39 Ensembl
GRCm381283,987,861 - 83,993,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1283,987,861 - 83,993,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,328,811 - 85,334,827 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361284,877,638 - 84,883,625 (+)NCBIMGSCv36mm8
Celera1285,434,445 - 85,440,461 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.99NCBI
Acot2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,341,426 - 109,352,818 (+)NCBIGRCr8
mRatBN7.26103,611,738 - 103,619,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,611,544 - 103,619,245 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6103,773,494 - 103,780,324 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,072,709 - 104,079,539 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,442,160 - 103,448,992 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,460,596 - 107,468,324 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,460,668 - 107,467,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,076,465 - 118,084,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,017,574 - 108,024,387 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,021,029 - 108,027,840 (+)NCBI
Celera6101,441,758 - 101,448,571 (+)NCBICelera
Cytogenetic Map6q31NCBI
ACOT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,655,251 - 74,665,746 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11473,874,828 - 73,889,496 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,128,445 - 54,135,067 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11472,985,087 - 72,993,182 (+)NCBIpanpan1.1PanPan1.1panPan2
ACOT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,851,109 - 46,873,354 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,852,880 - 46,911,640 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,535,270 - 46,544,386 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,079,920 - 47,089,052 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,081,692 - 47,140,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,747,622 - 46,756,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,731,860 - 46,774,959 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,121,855 - 47,164,838 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in ACOT2
49 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q24.2-32.2(chr14:72787506-99596719)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052293]|See cases [RCV000052293] Chr14:72787506..99596719 [GRCh38]
Chr14:73254214..100063056 [GRCh37]
Chr14:72323967..99132809 [NCBI36]
Chr14:14q24.2-32.2		 pathogenic
NM_006821.5(ACOT2):c.1040C>T (p.Thr347Ile) single nucleotide variant Malignant melanoma [RCV000062789] Chr14:73575101 [GRCh38]
Chr14:74041805 [GRCh37]
Chr14:73111558 [NCBI36]
Chr14:14q24.3		 not provided
GRCh37/hg19 14q24.2-q24.3(chr14:73152115..77698582) deletion Intellectual disability, mild [RCV000190520] Chr14:73152115..77698582 [GRCh37]
Chr14:14q24.2-24.3		 pathogenic|likely pathogenic
GRCh38/hg38 14q24.1-31.1(chr14:69562099-81975384)x1 copy number loss See cases [RCV000134154] Chr14:69562099..81975384 [GRCh38]
Chr14:70028816..82441728 [GRCh37]
Chr14:69098569..81511481 [NCBI36]
Chr14:14q24.1-31.1		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q24.3-31.1(chr14:73343213-78835059)x1 copy number loss See cases [RCV000143265] Chr14:73343213..78835059 [GRCh38]
Chr14:73809921..79301402 [GRCh37]
Chr14:72879674..78371155 [NCBI36]
Chr14:14q24.3-31.1		 pathogenic|likely pathogenic
GRCh37/hg19 14q24.3(chr14:74004581-74040262)x1 copy number loss See cases [RCV000446093] Chr14:74004581..74040262 [GRCh37]
Chr14:14q24.3		 benign
GRCh37/hg19 14q24.3(chr14:74008382-74040262)x1 copy number loss See cases [RCV000446398] Chr14:74008382..74040262 [GRCh37]
Chr14:14q24.3		 likely benign
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q24.3(chr14:74008382-74042276)x1 copy number loss See cases [RCV000447079] Chr14:74008382..74042276 [GRCh37]
Chr14:14q24.3		 benign
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3 copy number gain See cases [RCV000448557] Chr14:62493932..107285437 [GRCh37]
Chr14:14q23.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q24.3(chr14:74040231-76368547) copy number loss not provided [RCV000767572] Chr14:74040231..76368547 [GRCh37]
Chr14:14q24.3		 likely pathogenic
NM_006821.6(ACOT2):c.968T>C (p.Val323Ala) single nucleotide variant not specified [RCV004291304] Chr14:73575029 [GRCh38]
Chr14:74041733 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.242T>G (p.Val81Gly) single nucleotide variant not specified [RCV004328365] Chr14:73569482 [GRCh38]
Chr14:74036186 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.365T>G (p.Leu122Arg) single nucleotide variant not specified [RCV004303723] Chr14:73569605 [GRCh38]
Chr14:74036309 [GRCh37]
Chr14:14q24.3		 uncertain significance
GRCh37/hg19 14q24.2-32.33(chr14:73750741-107285437)x3 copy number gain See cases [RCV000512497] Chr14:73750741..107285437 [GRCh37]
Chr14:14q24.2-32.33		 pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q24.3(chr14:73964278-74061968)x3 copy number gain not provided [RCV000738538] Chr14:73964278..74061968 [GRCh37]
Chr14:14q24.3		 benign
GRCh37/hg19 14q24.3(chr14:73973256-74044260)x3 copy number gain not provided [RCV000738539] Chr14:73973256..74044260 [GRCh37]
Chr14:14q24.3		 benign
GRCh37/hg19 14q24.3(chr14:73976934-74044260)x3 copy number gain not provided [RCV000738540] Chr14:73976934..74044260 [GRCh37]
Chr14:14q24.3		 benign
GRCh37/hg19 14q24.3(chr14:73987553-74044260)x3 copy number gain not provided [RCV000738541] Chr14:73987553..74044260 [GRCh37]
Chr14:14q24.3		 benign
NM_006821.6(ACOT2):c.983A>G (p.His328Arg) single nucleotide variant not provided [RCV000845045] Chr14:73575044 [GRCh38]
Chr14:74041748 [GRCh37]
Chr14:14q24.3		 benign|not provided
NM_006821.6(ACOT2):c.63G>T (p.Met21Ile) single nucleotide variant not specified [RCV004332864] Chr14:73569303 [GRCh38]
Chr14:74036007 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1387C>G (p.Gln463Glu) single nucleotide variant not specified [RCV004326528] Chr14:73575448 [GRCh38]
Chr14:74042152 [GRCh37]
Chr14:14q24.3		 uncertain significance
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3 copy number gain 14q22.2q24.3 duplication [RCV001506967] Chr14:54654001..75828024 [GRCh37]
Chr14:14q22.2-24.3		 likely pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2 copy number gain See cases [RCV002286356] Chr14:37671058..106985955 [GRCh37]
Chr14:14q13.3-32.33		 pathogenic
NM_006821.6(ACOT2):c.1169A>G (p.Asn390Ser) single nucleotide variant not specified [RCV004074606] Chr14:73575230 [GRCh38]
Chr14:74041934 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.447G>T (p.Glu149Asp) single nucleotide variant not specified [RCV004197304] Chr14:73569687 [GRCh38]
Chr14:74036391 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1334T>C (p.Ile445Thr) single nucleotide variant not specified [RCV004234164] Chr14:73575395 [GRCh38]
Chr14:74042099 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1287C>A (p.Phe429Leu) single nucleotide variant not specified [RCV004199924] Chr14:73575348 [GRCh38]
Chr14:74042052 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.397A>C (p.Ser133Arg) single nucleotide variant not specified [RCV004179822] Chr14:73569637 [GRCh38]
Chr14:74036341 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.398G>T (p.Ser133Ile) single nucleotide variant not specified [RCV004179823] Chr14:73569638 [GRCh38]
Chr14:74036342 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.865G>A (p.Gly289Arg) single nucleotide variant not specified [RCV004136046] Chr14:73574926 [GRCh38]
Chr14:74041630 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.691G>A (p.Gly231Ser) single nucleotide variant not specified [RCV004091100] Chr14:73573435 [GRCh38]
Chr14:74040139 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.539G>A (p.Arg180Gln) single nucleotide variant not specified [RCV004168618] Chr14:73569779 [GRCh38]
Chr14:74036483 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1292T>C (p.Leu431Pro) single nucleotide variant not specified [RCV004142435] Chr14:73575353 [GRCh38]
Chr14:74042057 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.22C>G (p.Pro8Ala) single nucleotide variant not specified [RCV004125354] Chr14:73569262 [GRCh38]
Chr14:74035966 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.551A>C (p.Gln184Pro) single nucleotide variant not specified [RCV004278121] Chr14:73569791 [GRCh38]
Chr14:74036495 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.428T>C (p.Leu143Pro) single nucleotide variant not specified [RCV004277134] Chr14:73569668 [GRCh38]
Chr14:74036372 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.706C>T (p.Arg236Trp) single nucleotide variant not specified [RCV004253921] Chr14:73573450 [GRCh38]
Chr14:74040154 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1006C>G (p.Pro336Ala) single nucleotide variant not specified [RCV004266912] Chr14:73575067 [GRCh38]
Chr14:74041771 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.860G>A (p.Gly287Glu) single nucleotide variant not specified [RCV004258373] Chr14:73574921 [GRCh38]
Chr14:74041625 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1355C>T (p.Ala452Val) single nucleotide variant not specified [RCV004273948] Chr14:73575416 [GRCh38]
Chr14:74042120 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.41T>G (p.Val14Gly) single nucleotide variant not specified [RCV004277909] Chr14:73569281 [GRCh38]
Chr14:74035985 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.799C>A (p.Leu267Met) single nucleotide variant not specified [RCV004320214] Chr14:73573543 [GRCh38]
Chr14:74040247 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.454T>G (p.Leu152Val) single nucleotide variant not specified [RCV004347919] Chr14:73569694 [GRCh38]
Chr14:74036398 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.332A>G (p.His111Arg) single nucleotide variant not specified [RCV004335095] Chr14:73569572 [GRCh38]
Chr14:74036276 [GRCh37]
Chr14:14q24.3		 uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3 copy number gain not provided [RCV003485036] Chr14:58894502..107227240 [GRCh37]
Chr14:14q23.1-32.33		 pathogenic
NM_006821.6(ACOT2):c.263T>C (p.Leu88Pro) single nucleotide variant not specified [RCV004429999] Chr14:73569503 [GRCh38]
Chr14:74036207 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.578C>T (p.Pro193Leu) single nucleotide variant not specified [RCV004430042] Chr14:73569818 [GRCh38]
Chr14:74036522 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1221T>A (p.His407Gln) single nucleotide variant not specified [RCV004429958] Chr14:73575282 [GRCh38]
Chr14:74041986 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1423C>T (p.His475Tyr) single nucleotide variant not specified [RCV004429984] Chr14:73575484 [GRCh38]
Chr14:74042188 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.679G>A (p.Gly227Arg) single nucleotide variant not specified [RCV004430052] Chr14:73573423 [GRCh38]
Chr14:74040127 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.758A>G (p.Tyr253Cys) single nucleotide variant not specified [RCV004430056] Chr14:73573502 [GRCh38]
Chr14:74040206 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.218G>A (p.Gly73Asp) single nucleotide variant not specified [RCV004429991] Chr14:73569458 [GRCh38]
Chr14:74036162 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.820A>G (p.Met274Val) single nucleotide variant not specified [RCV004430061] Chr14:73573564 [GRCh38]
Chr14:74040268 [GRCh37]
Chr14:14q24.3		 likely benign
NM_006821.6(ACOT2):c.473G>T (p.Arg158Leu) single nucleotide variant not specified [RCV004430030] Chr14:73569713 [GRCh38]
Chr14:74036417 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.581C>G (p.Pro194Arg) single nucleotide variant not specified [RCV004430045] Chr14:73569821 [GRCh38]
Chr14:74036525 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1435A>G (p.Ile479Val) single nucleotide variant not specified [RCV004429990] Chr14:73575496 [GRCh38]
Chr14:74042200 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1426G>A (p.Glu476Lys) single nucleotide variant not specified [RCV004429987] Chr14:73575487 [GRCh38]
Chr14:74042191 [GRCh37]
Chr14:14q24.3		 likely benign
NM_006821.6(ACOT2):c.25C>T (p.His9Tyr) single nucleotide variant not specified [RCV004429997] Chr14:73569265 [GRCh38]
Chr14:74035969 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1325G>T (p.Ser442Ile) single nucleotide variant not specified [RCV004429966] Chr14:73575386 [GRCh38]
Chr14:74042090 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1354G>A (p.Ala452Thr) single nucleotide variant not specified [RCV004429974] Chr14:73575415 [GRCh38]
Chr14:74042119 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1363A>G (p.Met455Val) single nucleotide variant not specified [RCV004429980] Chr14:73575424 [GRCh38]
Chr14:74042128 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.432G>C (p.Trp144Cys) single nucleotide variant not specified [RCV004430023] Chr14:73569672 [GRCh38]
Chr14:74036376 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.350A>G (p.Asp117Gly) single nucleotide variant not specified [RCV004603999] Chr14:73569590 [GRCh38]
Chr14:74036294 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.554C>G (p.Thr185Arg) single nucleotide variant not specified [RCV004604009] Chr14:73569794 [GRCh38]
Chr14:74036498 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.911C>T (p.Ala304Val) single nucleotide variant not specified [RCV004604030] Chr14:73574972 [GRCh38]
Chr14:74041676 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.674T>A (p.Met225Lys) single nucleotide variant not specified [RCV004604020] Chr14:73573418 [GRCh38]
Chr14:74040122 [GRCh37]
Chr14:14q24.3		 uncertain significance
NM_006821.6(ACOT2):c.1036G>A (p.Val346Met) single nucleotide variant not specified [RCV004604038] Chr14:73575097 [GRCh38]
Chr14:74041801 [GRCh37]
Chr14:14q24.3		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:502
Count of miRNA genes:322
Interacting mature miRNAs:340
Transcripts:ENST00000238651, ENST00000538782, ENST00000557857
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407025825GWAS674801_Hundecenoylcarnitine (C11:1) measurement QTL GWAS674801 (human)3e-28undecenoylcarnitine (C11:1) measurement147357343273573433Human
406923685GWAS572661_Hbranched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement QTL GWAS572661 (human)4e-36branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement147357343273573433Human
406925988GWAS574964_HX-24747 measurement QTL GWAS574964 (human)1e-194X-24747 measurement147357294973572950Human
407093926GWAS742902_Hmetabolite measurement QTL GWAS742902 (human)4e-64metabolite measurement147357343273573433Human
407313697GWAS962673_H(2 or 3)-decenoate (10:1n7 or n8) measurement QTL GWAS962673 (human)6e-11(2 or 3)-decenoate (10:1n7 or n8) measurement147357343273573433Human
406910441GWAS559417_Hdodecadienoate (12:2) measurement QTL GWAS559417 (human)9e-47dodecadienoate (12:2) measurement147357343273573433Human
407314732GWAS963708_Hdodecadienoate (12:2) measurement QTL GWAS963708 (human)1e-24dodecadienoate (12:2) measurement147357343273573433Human
407068047GWAS717023_Hmetabolite measurement QTL GWAS717023 (human)2e-61metabolite measurement147357343273573433Human
407063341GWAS712317_Hbranched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement QTL GWAS712317 (human)1e-16branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement147357343273573433Human
407153236GWAS802212_Hurinary metabolite measurement QTL GWAS802212 (human)1e-52urinary metabolite measurement147356990973569910Human
407026130GWAS675106_Hdodecadienoate (12:2) measurement QTL GWAS675106 (human)1e-43dodecadienoate (12:2) measurement147357343273573433Human
407094003GWAS742979_H(2 or 3)-decenoate (10:1n7 or n8) measurement QTL GWAS742979 (human)7e-15(2 or 3)-decenoate (10:1n7 or n8) measurement147357343273573433Human
407065430GWAS714406_Hdodecadienoate (12:2) measurement QTL GWAS714406 (human)6e-23dodecadienoate (12:2) measurement147357343273573433Human
407312368GWAS961344_Hbranched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement QTL GWAS961344 (human)2e-17branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement147357343273573433Human
407026426GWAS675402_Hbranched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement QTL GWAS675402 (human)5e-28branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement147357343273573433Human
407026425GWAS675401_Hbranched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement QTL GWAS675401 (human)2e-12branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid measurement147357073673570737Human

Markers in Region
A002Q22  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,042,089 - 74,042,300UniSTSGRCh37
GRCh371474,010,231 - 74,010,442UniSTSGRCh37
Build 361473,079,984 - 73,080,195RGDNCBI36
Celera1433,178,783 - 33,178,994RGD
Celera1454,078,184 - 54,078,395UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1454,177,097 - 54,177,308UniSTS
HuRef1454,209,868 - 54,210,079UniSTS
GeneMap99-GB4 RH Map14190.82UniSTS
NCBI RH Map14820.0UniSTS
D14S1209  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,038,288 - 74,038,463UniSTSGRCh37
GRCh371474,006,374 - 74,006,549UniSTSGRCh37
Build 361473,076,127 - 73,076,302RGDNCBI36
Celera1433,183,002 - 33,183,177RGD
Celera1454,074,385 - 54,074,560UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1454,173,241 - 54,173,416UniSTS
HuRef1454,206,063 - 54,206,238UniSTS
ZAP128_9204  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,041,738 - 74,042,410UniSTSGRCh37
GRCh371474,009,880 - 74,010,551UniSTSGRCh37
Build 361473,079,633 - 73,080,304RGDNCBI36
Celera1454,077,833 - 54,078,505RGD
HuRef1454,209,517 - 54,210,189UniSTS
HuRef1454,176,746 - 54,177,418UniSTS
D14S1367  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,041,832 - 74,041,950UniSTSGRCh37
GRCh371474,009,974 - 74,010,092UniSTSGRCh37
Build 361473,079,727 - 73,079,845RGDNCBI36
Celera1433,179,133 - 33,179,251RGD
Celera1454,077,927 - 54,078,045UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1454,176,840 - 54,176,958UniSTS
HuRef1454,209,611 - 54,209,729UniSTS
D14S1377  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,035,841 - 74,035,958UniSTSGRCh37
Build 361473,105,594 - 73,105,711RGDNCBI36
Celera1454,071,939 - 54,072,056RGD
Cytogenetic Map14q24.3UniSTS
HuRef1454,203,617 - 54,203,734UniSTS
G38315  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,035,554 - 74,035,706UniSTSGRCh37
GRCh371474,003,527 - 74,003,679UniSTSGRCh37
Build 361473,073,280 - 73,073,432RGDNCBI36
Celera1433,185,872 - 33,186,024RGD
Celera1454,071,652 - 54,071,804UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1454,170,397 - 54,170,549UniSTS
HuRef1454,203,330 - 54,203,482UniSTS
D14S646E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,042,010 - 74,042,150UniSTSGRCh37
GRCh371474,010,152 - 74,010,292UniSTSGRCh37
Build 361473,079,905 - 73,080,045RGDNCBI36
Celera1433,178,933 - 33,179,073RGD
Celera1454,078,105 - 54,078,245UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1454,177,018 - 54,177,158UniSTS
HuRef1454,209,789 - 54,209,929UniSTS
GeneMap99-GB4 RH Map14191.19UniSTS
NCBI RH Map14748.2UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2436 2788 2245 4944 1723 2349 5 623 1936 465 2269 7277 6448 49 3705 849 1737 1614 171 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001364177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_046028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC245368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI537078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK093131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK223635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY005822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ082755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L40401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000238651   ⟹   ENSP00000238651
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1473,569,213 - 73,575,655 (+)Ensembl
Ensembl Acc Id: ENST00000538782   ⟹   ENSP00000440961
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1473,567,620 - 73,575,653 (+)Ensembl
Ensembl Acc Id: ENST00000557857
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1473,574,304 - 73,575,201 (+)Ensembl
Ensembl Acc Id: ENST00000613168   ⟹   ENSP00000477685
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1473,569,285 - 73,575,658 (+)Ensembl
Ensembl Acc Id: ENST00000622407   ⟹   ENSP00000483704
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1473,569,115 - 73,575,653 (+)Ensembl
RefSeq Acc Id: NM_001364177   ⟹   NP_001351106
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,569,059 - 73,575,658 (+)NCBI
T2T-CHM13v2.01467,776,569 - 67,783,167 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001364178   ⟹   NP_001351107
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,569,059 - 73,574,407 (+)NCBI
T2T-CHM13v2.01467,776,569 - 67,781,916 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006821   ⟹   NP_006812
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,569,213 - 73,575,655 (+)NCBI
GRCh371474,034,324 - 74,042,362 (+)NCBI
Build 361473,105,525 - 73,112,112 (+)NCBI Archive
Celera1454,071,870 - 54,078,454 (+)RGD
HuRef1454,202,099 - 54,210,141 (+)NCBI
CHM1_11473,975,353 - 73,981,955 (+)NCBI
T2T-CHM13v2.01467,776,723 - 67,783,164 (+)NCBI
Sequence:
RefSeq Acc Id: NR_046028
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,567,620 - 73,575,658 (+)NCBI
GRCh371474,034,324 - 74,042,362 (+)NCBI
HuRef1454,202,099 - 54,210,141 (+)NCBI
CHM1_11473,973,914 - 73,981,955 (+)NCBI
T2T-CHM13v2.01467,775,130 - 67,783,167 (+)NCBI
Sequence:
RefSeq Acc Id: NP_006812   ⟸   NM_006821
- Peptide Label: isoform 1
- UniProtKB: Q53EK4 (UniProtKB/Swiss-Prot),   Q3I5F8 (UniProtKB/Swiss-Prot),   Q9NUX4 (UniProtKB/Swiss-Prot),   P49753 (UniProtKB/Swiss-Prot),   A0A087WT95 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001351106   ⟸   NM_001364177
- Peptide Label: isoform 2
- UniProtKB: B3KSA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001351107   ⟸   NM_001364178
- Peptide Label: isoform 3
Ensembl Acc Id: ENSP00000483704   ⟸   ENST00000622407
Ensembl Acc Id: ENSP00000477685   ⟸   ENST00000613168
Ensembl Acc Id: ENSP00000440961   ⟸   ENST00000538782
Ensembl Acc Id: ENSP00000238651   ⟸   ENST00000238651
Protein Domains
Acyl-CoA thioester hydrolase/bile acid-CoA amino   BAAT/Acyl-CoA thioester hydrolase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49753-F1-model_v2 AlphaFold P49753 1-483 view protein structure

Promoters
RGD ID:6791229
Promoter ID:HG_KWN:19744
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_006821
Position:
Human AssemblyChrPosition (strand)Source
Build 361473,105,681 - 73,106,322 (+)MPROMDB
RGD ID:7228095
Promoter ID:EPDNEW_H19794
Type:initiation region
Name:ACOT2_2
Description:acyl-CoA thioesterase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19795  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,569,085 - 73,569,145EPDNEW
RGD ID:7228101
Promoter ID:EPDNEW_H19795
Type:initiation region
Name:ACOT2_1
Description:acyl-CoA thioesterase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19794  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381473,569,276 - 73,569,336EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18431 AgrOrtholog
COSMIC ACOT2 COSMIC
Ensembl Genes ENSG00000119673 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000238651 ENTREZGENE
  ENST00000238651.10 UniProtKB/Swiss-Prot
  ENST00000538782 ENTREZGENE
  ENST00000538782.2 UniProtKB/TrEMBL
  ENST00000613168.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000119673 GTEx
HGNC ID HGNC:18431 ENTREZGENE
Human Proteome Map ACOT2 Human Proteome Map
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl-CoA_thioEstase_long-chain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thio_Ohase/aa_AcTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thio_Ohase/BAAT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10965 UniProtKB/Swiss-Prot
NCBI Gene 10965 ENTREZGENE
OMIM 609972 OMIM
PANTHER ACYL-COENZYME A THIOESTERASE 1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACYL-COENZYME A THIOESTERASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bile_Hydr_Trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142672653 PharmGKB
PIRSF Acyl-CoA_hydro UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WT95 ENTREZGENE, UniProtKB/TrEMBL
  ACOT2_HUMAN UniProtKB/Swiss-Prot
  B3KSA0 ENTREZGENE, UniProtKB/TrEMBL
  F6VI00_HUMAN UniProtKB/TrEMBL
  P49753 ENTREZGENE
  Q3I5F8 ENTREZGENE
  Q53EK4 ENTREZGENE
  Q9NUX4 ENTREZGENE
UniProt Secondary Q3I5F8 UniProtKB/Swiss-Prot
  Q53EK4 UniProtKB/Swiss-Prot
  Q9NUX4 UniProtKB/Swiss-Prot