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Gene: SAFB (scaffold attachment factor B) Homo sapiens
Symbol: SAFB
Name: scaffold attachment factor B
Description: Exhibits RNA binding activity. Predicted to be involved in intracellular estrogen receptor signaling pathway; regulation of mRNA processing; and regulation of transcription by RNA polymerase II. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp779C1727; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; SAF-B; SAF-B1; SAFB1; scaffold attachment factor B1
Mus musculus (house mouse) : Safb (scaffold attachment factor B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Safb (scaffold attachment factor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Safb (scaffold attachment factor B)
Pan paniscus (bonobo/pygmy chimpanzee) : SAFB (scaffold attachment factor B)
Canis lupus familiaris (dog) : SAFB (scaffold attachment factor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Safb (scaffold attachment factor B)
Sus scrofa (pig) : SAFB (scaffold attachment factor B)
Chlorocebus sabaeus (African green monkey) : SAFB (scaffold attachment factor B)
Heterocephalus glaber (naked mole-rat) : Safb (scaffold attachment factor B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl195,623,035 - 5,668,478 (+)EnsemblGRCh38hg38GRCh38
GRCh38195,623,081 - 5,668,478 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37195,623,046 - 5,668,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36195,574,164 - 5,619,489 (+)NCBINCBI36hg18NCBI36
Build 34195,574,163 - 5,619,488NCBI
Celera195,560,521 - 5,605,843 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef195,384,164 - 5,429,603 (+)NCBIHuRef
CHM1_1195,622,638 - 5,668,071 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SAFB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733074
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.