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Gene: LY6E (lymphocyte antigen 6 family member E) Homo sapiens
Symbol: LY6E
Name: lymphocyte antigen 6 family member E
Description: Predicted to have acetylcholine receptor inhibitor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to localize to the plasma membrane; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2-bromohexadecanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ly-6E; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6E; retinoic acid induced gene E; retinoic acid-induced gene E protein; RIG-E; RIGE; SCA-2; SCA2; stem cell antigen 2; thymic shared antigen 1; TSA-1
Mus musculus (house mouse) : Ly6e (lymphocyte antigen 6 complex, locus E)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ly6e (lymphocyte antigen 6 family member E)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LY6E (lymphocyte antigen 6 family member E)
Canis lupus familiaris (dog) : LY6E (lymphocyte antigen 6 family member E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ly6e (lymphocyte antigen 6 family member E)
Sus scrofa (pig) : LY6E (lymphocyte antigen 6 family member E)
Chlorocebus sabaeus (African green monkey) : LY6E (lymphocyte antigen 6 family member E)
Heterocephalus glaber (naked mole-rat) : Ly6e (lymphocyte antigen 6 family member E)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8143,017,982 - 143,023,832 (+)Ensembl
GRCh388143,018,485 - 143,022,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,099,902 - 144,103,827 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,171,300 - 144,175,199 (+)NCBINCBI36hg18NCBI36
Build 348144,171,299 - 144,175,199NCBI
Celera8140,409,515 - 140,413,440 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8139,353,438 - 139,357,363 (+)NCBIHuRef
CHM1_18144,140,603 - 144,144,526 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LY6E
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351321
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.