HNRNPD (heterogeneous nuclear ribonucleoprotein D) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: HNRNPD (heterogeneous nuclear ribonucleoprotein D) Homo sapiens
Analyze
Symbol: HNRNPD
Name: heterogeneous nuclear ribonucleoprotein D
RGD ID: 733451
HGNC Page HGNC
Description: Enables RNA binding activity and telomeric DNA binding activity. Involved in circadian regulation of translation; positive regulation of translation; and regulation of circadian rhythm. Located in nucleoplasm. Part of ribonucleoprotein complex. Biomarker of hepatocellular carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARE-binding protein AUFI, type A; AU-rich element RNA binding protein 1, 37kDa; AU-rich element RNA-binding protein 1; AUF1; AUF1A; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; hnRNPD0; HNRPD; P37; rna binding protein p45auf1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: HNRNPDP1   HNRNPDP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl482,352,498 - 82,374,503 (-)EnsemblGRCh38hg38GRCh38
GRCh38482,352,498 - 82,373,991 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37483,273,651 - 83,295,144 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36483,493,491 - 83,514,173 (-)NCBINCBI36hg18NCBI36
Build 34483,631,645 - 83,652,328NCBI
Celera480,565,274 - 80,585,965 (-)NCBI
Cytogenetic Map4q21.22NCBI
HuRef479,014,546 - 79,035,236 (-)NCBIHuRef
CHM1_1483,250,972 - 83,271,667 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (EXP)
(Z)-3-butylidenephthalide  (EXP)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (EXP)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (EXP)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butanal  (EXP)
cadmium sulfate  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
curcumin  (EXP)
cyclosporin A  (EXP)
daunorubicin  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dihydroartemisinin  (EXP)
disodium selenite  (EXP)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
elemental selenium  (EXP)
enzyme inhibitor  (EXP)
ethyl methanesulfonate  (EXP)
fenvalerate  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
hydrogen sulfide  (ISO)
irinotecan  (EXP)
ivermectin  (EXP)
lead(0)  (EXP)
lead(2+)  (EXP)
lead(II) chloride  (EXP)
lipopolysaccharide  (EXP,ISO)
methotrexate  (ISO)
methyl methanesulfonate  (EXP)
methylmercury chloride  (EXP)
methylparaben  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (EXP)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
piroxicam  (EXP)
putrescine  (ISO)
quercetin  (EXP)
quinoline  (EXP)
resveratrol  (ISO)
SB 431542  (EXP)
selenium atom  (EXP)
sevoflurane  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP)
Soman  (ISO)
tetrachloromethane  (ISO)
topotecan  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (EXP,ISO)
valproic acid  (EXP)
vincristine  (EXP)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3'-UTR-mediated mRNA destabilization  (IEA,ISO)
brain development  (ISO)
cellular response to amino acid stimulus  (IEA,ISO)
cellular response to estradiol stimulus  (IEA,ISO)
cellular response to nitric oxide  (IEA,ISO)
cellular response to putrescine  (IEA,ISO)
cerebellum development  (IEA,ISO)
circadian regulation of translation  (IMP)
CRD-mediated mRNA stabilization  (IDA)
hepatocyte dedifferentiation  (IEA,ISO)
liver development  (IEA,ISO)
mRNA stabilization  (ISO)
mRNA transcription by RNA polymerase II  (ISS)
negative regulation of gene expression  (ISO)
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (IDA)
positive regulation of cytoplasmic translation  (IDA)
positive regulation of gene expression  (ISO)
positive regulation of telomerase RNA reverse transcriptase activity  (ISS)
positive regulation of telomere capping  (ISS)
positive regulation of transcription by RNA polymerase II  (ISS)
positive regulation of transcription, DNA-templated  (NAS)
positive regulation of translation  (IMP)
regulation of circadian rhythm  (IMP)
regulation of gene expression  (IBA)
regulation of mRNA stability  (ISO)
regulation of telomere maintenance  (ISS)
regulation of transcription, DNA-templated  (NAS)
response to calcium ion  (IEA,ISO)
response to electrical stimulus  (IEA,ISO)
response to estradiol  (ISO)
response to rapamycin  (IEA,ISO)
response to sodium phosphate  (IEA,ISO)
response to xenobiotic stimulus  (ISO)
RNA catabolic process  (TAS)
RNA processing  (TAS)

Cellular Component
cytoplasm  (IEA)
cytosol  (IDA,ISO,TAS)
mCRD-mediated mRNA stability complex  (IPI)
nucleoplasm  (IBA,IDA,TAS)
nucleus  (IEA,ISO,NAS)
ribonucleoprotein complex  (IDA)
synapse  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1433497   PMID:3754960   PMID:7673195   PMID:8246982   PMID:8321232   PMID:8661052   PMID:9234743   PMID:9521873   PMID:9615222   PMID:9632798   PMID:10024518   PMID:10080887  
PMID:10205060   PMID:10373504   PMID:10900464   PMID:10933876   PMID:11051545   PMID:11531333   PMID:11856759   PMID:11903055   PMID:12107167   PMID:12226669   PMID:12356764   PMID:12388589  
PMID:12477932   PMID:12674497   PMID:12819194   PMID:12819195   PMID:14559993   PMID:14585195   PMID:14711832   PMID:14769789   PMID:15047060   PMID:15231747   PMID:15257295   PMID:15302935  
PMID:15489334   PMID:15514034   PMID:15659558   PMID:15734733   PMID:15782174   PMID:15815621   PMID:15834135   PMID:15951444   PMID:16094384   PMID:16109718   PMID:16144962   PMID:16155006  
PMID:16236267   PMID:16289864   PMID:16335786   PMID:16341674   PMID:16494882   PMID:16556936   PMID:16571724   PMID:16835382   PMID:16902409   PMID:16954375   PMID:17030625   PMID:17081983  
PMID:17289661   PMID:17486099   PMID:17620599   PMID:17626845   PMID:17643375   PMID:17878526   PMID:18029348   PMID:18202450   PMID:18240226   PMID:18413351   PMID:18457437   PMID:18573886  
PMID:18650551   PMID:18842733   PMID:18844578   PMID:18850631   PMID:19015635   PMID:19074427   PMID:19380743   PMID:19454010   PMID:19574297   PMID:19738201   PMID:19759913   PMID:20000738  
PMID:20348541   PMID:20360068   PMID:20467437   PMID:20489206   PMID:20571027   PMID:20926381   PMID:21081503   PMID:21081666   PMID:21135123   PMID:21145461   PMID:21245386   PMID:21319273  
PMID:21549307   PMID:21642987   PMID:21733716   PMID:21799732   PMID:21873635   PMID:21900206   PMID:21942715   PMID:21956942   PMID:22086907   PMID:22134169   PMID:22159912   PMID:22174317  
PMID:22187150   PMID:22203679   PMID:22365833   PMID:22368252   PMID:22431556   PMID:22446626   PMID:22623428   PMID:22658674   PMID:22681889   PMID:22751105   PMID:22863883   PMID:22939629  
PMID:23012480   PMID:23109422   PMID:23125841   PMID:23131833   PMID:23151878   PMID:23184937   PMID:23376485   PMID:23398456   PMID:23463506   PMID:23530064   PMID:23572232   PMID:23603392  
PMID:23825951   PMID:23874603   PMID:23940053   PMID:24158514   PMID:24189400   PMID:24213928   PMID:24244333   PMID:24332808   PMID:24337577   PMID:24416409   PMID:24423872   PMID:24457600  
PMID:24591637   PMID:24654937   PMID:24687816   PMID:24690621   PMID:24711643   PMID:24798327   PMID:24999758   PMID:25077793   PMID:25078689   PMID:25192599   PMID:25231991   PMID:25261470  
PMID:25324306   PMID:25349213   PMID:25366541   PMID:25437307   PMID:25486179   PMID:25515538   PMID:25720531   PMID:25787750   PMID:25798074   PMID:25900982   PMID:25908445   PMID:25910425  
PMID:25921289   PMID:25963833   PMID:26253535   PMID:26269332   PMID:26318153   PMID:26344197   PMID:26485645   PMID:26496610   PMID:26641092   PMID:26648300   PMID:26728997   PMID:26760575  
PMID:26805816   PMID:26831064   PMID:26925783   PMID:26979993   PMID:27025967   PMID:27129302   PMID:27182664   PMID:27248496   PMID:27248826   PMID:27437398   PMID:27520967   PMID:27576135  
PMID:27578251   PMID:27591049   PMID:27784781   PMID:27826622   PMID:27836661   PMID:27976729   PMID:28027390   PMID:28031328   PMID:28225217   PMID:28291226   PMID:28300425   PMID:28302793  
PMID:28319085   PMID:28334781   PMID:28515276   PMID:28712289   PMID:28927264   PMID:28977666   PMID:28986222   PMID:29053956   PMID:29117863   PMID:29180619   PMID:29228324   PMID:29229926  
PMID:29263134   PMID:29263261   PMID:29298432   PMID:29331416   PMID:29395067   PMID:29467282   PMID:29507755   PMID:29511337   PMID:29656893   PMID:29715546   PMID:29777862   PMID:29802200  
PMID:29845934   PMID:29884807   PMID:29955894   PMID:30021884   PMID:30181254   PMID:30196744   PMID:30209976   PMID:30349055   PMID:30349226   PMID:30418981   PMID:30425250   PMID:30463901  
PMID:30559450   PMID:30575818   PMID:30635654   PMID:30681073   PMID:30799487   PMID:30804502   PMID:30833792   PMID:30890647   PMID:30927204   PMID:30940648   PMID:30948266   PMID:30997501  
PMID:31048545   PMID:31059266   PMID:31091453   PMID:31152661   PMID:31180492   PMID:31239290   PMID:31253590   PMID:31300519   PMID:31326364   PMID:31353912   PMID:31405213   PMID:31501420  
PMID:31536960   PMID:31586073   PMID:31640799   PMID:31657090   PMID:31665637   PMID:31665914   PMID:31751430   PMID:31995728   PMID:32020881   PMID:32041737   PMID:32106863   PMID:32129710  
PMID:32457219   PMID:32491174   PMID:32529326   PMID:32538781   PMID:32552912   PMID:32665550   PMID:32807901   PMID:32814086   PMID:32877691   PMID:32905556   PMID:32994395   PMID:33016643  
PMID:33022573   PMID:33194618   PMID:33306668   PMID:33444453   PMID:33542193   PMID:33742100   PMID:33767152   PMID:34079125  


Genomics

Comparative Map Data
HNRNPD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl482,352,498 - 82,374,503 (-)EnsemblGRCh38hg38GRCh38
GRCh38482,352,498 - 82,373,991 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37483,273,651 - 83,295,144 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36483,493,491 - 83,514,173 (-)NCBINCBI36hg18NCBI36
Build 34483,631,645 - 83,652,328NCBI
Celera480,565,274 - 80,585,965 (-)NCBI
Cytogenetic Map4q21.22NCBI
HuRef479,014,546 - 79,035,236 (-)NCBIHuRef
CHM1_1483,250,972 - 83,271,667 (-)NCBICHM1_1
Hnrnpd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395100,103,794 - 100,126,926 (-)NCBIGRCm39mm39
GRCm39 Ensembl5100,103,794 - 100,126,797 (-)Ensembl
GRCm38599,955,935 - 99,979,130 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl599,955,935 - 99,978,938 (-)EnsemblGRCm38mm10GRCm38
MGSCv375100,384,955 - 100,407,957 (-)NCBIGRCm37mm9NCBIm37
MGSCv365100,201,309 - 100,218,851 (-)NCBImm8
Celera597,269,494 - 97,292,491 (-)NCBICelera
Cytogenetic Map5E4NCBI
Hnrnpd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2149,615,375 - 9,638,975 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl149,615,479 - 9,633,786 (+)Ensembl
Rnor_6.01411,256,163 - 11,274,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1411,256,268 - 11,274,578 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01411,200,186 - 11,218,696 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41410,917,674 - 10,935,989 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11410,917,909 - 10,935,760 (+)NCBI
Celera149,716,133 - 9,734,433 (+)NCBICelera
Cytogenetic Map14p22NCBI
Hnrnpd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554336,454,454 - 6,469,904 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554336,452,931 - 6,470,209 (-)NCBIChiLan1.0ChiLan1.0
HNRNPD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1447,675,382 - 47,696,894 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl447,676,599 - 47,696,894 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0441,825,518 - 41,846,166 (+)NCBIMhudiblu_PPA_v0panPan3
HNRNPD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,323,444 - 6,341,238 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,323,469 - 6,341,166 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3235,539,639 - 35,557,456 (+)NCBI
ROS_Cfam_1.0326,346,646 - 6,364,470 (-)NCBI
UMICH_Zoey_3.1326,376,955 - 6,394,761 (-)NCBI
UNSW_CanFamBas_1.0326,283,881 - 6,301,733 (-)NCBI
UU_Cfam_GSD_1.03233,661,515 - 33,679,335 (+)NCBI
Hnrnpd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052855,934,255 - 5,953,306 (+)NCBI
SpeTri2.0NW_0049367382,096,370 - 2,115,135 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8135,844,487 - 135,862,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18135,844,492 - 135,862,633 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28145,204,594 - 145,218,439 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1730,729,697 - 30,749,793 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl730,731,175 - 30,749,876 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660379,284,119 - 9,304,361 (-)NCBIVero_WHO_p1.0
Hnrnpd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247578,532,373 - 8,549,840 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
G33930  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,289,804 - 83,290,044UniSTSGRCh37
Build 36483,508,828 - 83,509,068RGDNCBI36
Celera480,580,611 - 80,580,851RGD
Cytogenetic Map4q21UniSTS
HuRef479,029,883 - 79,030,123UniSTS
SHGC-31001  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,281,823 - 83,281,947UniSTSGRCh37
Build 36483,500,847 - 83,500,971RGDNCBI36
Celera480,572,630 - 80,572,754RGD
Cytogenetic Map4q21UniSTS
HuRef479,021,902 - 79,022,026UniSTS
TNG Radiation Hybrid Map449056.0UniSTS
Stanford-G3 RH Map44466.0UniSTS
NCBI RH Map4993.1UniSTS
GeneMap99-G3 RH Map44450.0UniSTS
SHGC-59708  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,291,916 - 83,292,056UniSTSGRCh37
Build 36483,510,940 - 83,511,080RGDNCBI36
Celera480,582,722 - 80,582,862RGD
Cytogenetic Map4q21UniSTS
HuRef479,031,998 - 79,032,138UniSTS
SHGC-67336  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,294,817 - 83,295,051UniSTSGRCh37
Build 36483,513,841 - 83,514,075RGDNCBI36
Celera480,585,633 - 80,585,867RGD
Cytogenetic Map4q21UniSTS
HuRef479,034,904 - 79,035,138UniSTS
GeneMap99-GB4 RH Map4448.41UniSTS
SHGC-67254  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,288,209 - 83,288,427UniSTSGRCh37
Build 36483,507,233 - 83,507,451RGDNCBI36
Celera480,579,016 - 80,579,234RGD
Cytogenetic Map4q21UniSTS
HuRef479,028,288 - 79,028,506UniSTS
TNG Radiation Hybrid Map449056.0UniSTS
SHGC-24787  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,274,539 - 83,274,688UniSTSGRCh37
Build 36483,493,563 - 83,493,712RGDNCBI36
Celera480,565,346 - 80,565,495RGD
Cytogenetic Map4q21UniSTS
HuRef479,014,618 - 79,014,767UniSTS
GeneMap99-GB4 RH Map4448.71UniSTS
Whitehead-RH Map4492.9UniSTS
NCBI RH Map4977.8UniSTS
GeneMap99-G3 RH Map48670.0UniSTS
RH136938  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,275,033 - 83,275,213UniSTSGRCh37
Build 36483,494,057 - 83,494,237RGDNCBI36
Celera480,565,840 - 80,566,020RGD
HuRef479,015,112 - 79,015,292UniSTS
D4S1212  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,289,751 - 83,289,912UniSTSGRCh37
Build 36483,508,775 - 83,508,936RGDNCBI36
Celera480,580,558 - 80,580,719RGD
Cytogenetic Map4q21UniSTS
HuRef479,029,830 - 79,029,991UniSTS
TNG Radiation Hybrid Map449205.0UniSTS
STS-N23160  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,288,287 - 83,288,435UniSTSGRCh37
Build 36483,507,311 - 83,507,459RGDNCBI36
Celera480,579,094 - 80,579,242RGD
Cytogenetic Map4q21UniSTS
HuRef479,028,366 - 79,028,514UniSTS
GeneMap99-GB4 RH Map4444.44UniSTS
NCBI RH Map4984.8UniSTS
SHGC-51763  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,274,628 - 83,274,841UniSTSGRCh37
Build 36483,493,652 - 83,493,865RGDNCBI36
Celera480,565,435 - 80,565,648RGD
Cytogenetic Map4q21UniSTS
HuRef479,014,707 - 79,014,920UniSTS
TNG Radiation Hybrid Map449063.0UniSTS
SHGC-59507  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,274,647 - 83,274,813UniSTSGRCh37
Build 36483,493,671 - 83,493,837RGDNCBI36
Celera480,565,454 - 80,565,620RGD
Cytogenetic Map4q21UniSTS
HuRef479,014,726 - 79,014,892UniSTS
TNG Radiation Hybrid Map449063.0UniSTS
GeneMap99-GB4 RH Map4443.76UniSTS
NCBI RH Map4971.9UniSTS
SHGC-67972  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,290,664 - 83,290,780UniSTSGRCh37
Build 36483,509,688 - 83,509,804RGDNCBI36
Celera480,581,471 - 80,581,587RGD
Cytogenetic Map4q21UniSTS
HuRef479,030,743 - 79,030,863UniSTS
TNG Radiation Hybrid Map449063.0UniSTS
GeneMap99-GB4 RH Map4444.48UniSTS
NCBI RH Map4974.2UniSTS
MARC_23646-23647:1029444341:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,279,862 - 83,280,669UniSTSGRCh37
Build 36483,498,886 - 83,499,693RGDNCBI36
Celera480,570,669 - 80,571,476RGD
HuRef479,019,941 - 79,020,748UniSTS
MARC_23648-23649:1029444924:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,277,778 - 83,278,559UniSTSGRCh37
Build 36483,496,802 - 83,497,583RGDNCBI36
Celera480,568,585 - 80,569,366RGD
HuRef479,017,857 - 79,018,638UniSTS
MARC_23650-23651:1029445581:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,275,199 - 83,276,126UniSTSGRCh37
Build 36483,494,223 - 83,495,150RGDNCBI36
Celera480,566,006 - 80,566,933RGD
HuRef479,015,278 - 79,016,205UniSTS
HNRPD_3237  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37483,274,422 - 83,275,072UniSTSGRCh37
Build 36483,493,446 - 83,494,096RGDNCBI36
Celera480,565,229 - 80,565,879RGD
HuRef479,014,501 - 79,015,151UniSTS
Hnrnpd  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X63,264,940 - 63,265,198UniSTSGRCh37
CeleraX63,611,782 - 63,612,040UniSTS
HuRefX57,090,060 - 57,090,318UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2057
Count of miRNA genes:801
Interacting mature miRNAs:906
Transcripts:ENST00000313899, ENST00000352301, ENST00000353341, ENST00000503822, ENST00000507010, ENST00000508119, ENST00000509107, ENST00000509263, ENST00000513584, ENST00000514325, ENST00000514671, ENST00000515432, ENST00000541060, ENST00000543098
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2432 2943 1720 620 1937 462 4355 2163 3689 417 1449 1607 171 1204 2788 4
Low 7 48 6 4 14 3 2 34 45 2 11 6 4 1 2 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001003810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF039575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK057836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF693760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG180865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG180941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG325979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM825808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM832779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D55671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D55672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D55673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D55674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB887011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC944420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M94630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000313899   ⟹   ENSP00000313199
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,352,498 - 82,373,991 (-)Ensembl
RefSeq Acc Id: ENST00000352301   ⟹   ENSP00000305860
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,353,834 - 82,373,983 (-)Ensembl
RefSeq Acc Id: ENST00000353341   ⟹   ENSP00000313327
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,353,829 - 82,373,986 (-)Ensembl
RefSeq Acc Id: ENST00000503822   ⟹   ENSP00000422615
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,358,758 - 82,374,161 (-)Ensembl
RefSeq Acc Id: ENST00000507010   ⟹   ENSP00000421952
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,357,403 - 82,374,144 (-)Ensembl
RefSeq Acc Id: ENST00000508119
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,354,847 - 82,357,392 (-)Ensembl
RefSeq Acc Id: ENST00000509107   ⟹   ENSP00000425439
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,359,516 - 82,373,985 (-)Ensembl
RefSeq Acc Id: ENST00000509263   ⟹   ENSP00000420926
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,356,554 - 82,373,150 (-)Ensembl
RefSeq Acc Id: ENST00000513584   ⟹   ENSP00000424002
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,355,249 - 82,373,991 (-)Ensembl
RefSeq Acc Id: ENST00000514325
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,353,829 - 82,358,842 (-)Ensembl
RefSeq Acc Id: ENST00000514671   ⟹   ENSP00000426446
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,353,834 - 82,359,639 (-)Ensembl
RefSeq Acc Id: ENST00000515432   ⟹   ENSP00000426666
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl482,357,437 - 82,374,503 (-)Ensembl
RefSeq Acc Id: NM_001003810   ⟹   NP_001003810
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38482,352,498 - 82,373,991 (-)NCBI
GRCh37483,274,467 - 83,295,149 (-)ENTREZGENE
Build 36483,493,491 - 83,514,173 (-)NCBI Archive
HuRef479,014,546 - 79,035,236 (-)ENTREZGENE
CHM1_1483,250,972 - 83,271,667 (-)NCBI
Sequence:
RefSeq Acc Id: NM_002138   ⟹   NP_002129
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38482,352,498 - 82,373,991 (-)NCBI
GRCh37483,274,467 - 83,295,149 (-)ENTREZGENE
Build 36483,493,491 - 83,514,173 (-)NCBI Archive
HuRef479,014,546 - 79,035,236 (-)ENTREZGENE
CHM1_1483,250,972 - 83,271,667 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031369   ⟹   NP_112737
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38482,352,498 - 82,373,991 (-)NCBI
GRCh37483,274,467 - 83,295,149 (-)ENTREZGENE
Build 36483,493,491 - 83,514,173 (-)NCBI Archive
HuRef479,014,546 - 79,035,236 (-)ENTREZGENE
CHM1_1483,250,972 - 83,271,667 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031370   ⟹   NP_112738
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38482,352,498 - 82,373,991 (-)NCBI
GRCh37483,274,467 - 83,295,149 (-)ENTREZGENE
Build 36483,493,491 - 83,514,173 (-)NCBI Archive
HuRef479,014,546 - 79,035,236 (-)ENTREZGENE
CHM1_1483,250,972 - 83,271,667 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003810 (Get FASTA)   NCBI Sequence Viewer  
  NP_002129 (Get FASTA)   NCBI Sequence Viewer  
  NP_112737 (Get FASTA)   NCBI Sequence Viewer  
  NP_112738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA35781 (Get FASTA)   NCBI Sequence Viewer  
  AAB96683 (Get FASTA)   NCBI Sequence Viewer  
  AAC23474 (Get FASTA)   NCBI Sequence Viewer  
  AAC23475 (Get FASTA)   NCBI Sequence Viewer  
  AAC23476 (Get FASTA)   NCBI Sequence Viewer  
  AAH02401 (Get FASTA)   NCBI Sequence Viewer  
  AAH23977 (Get FASTA)   NCBI Sequence Viewer  
  AAH26015 (Get FASTA)   NCBI Sequence Viewer  
  AAY40913 (Get FASTA)   NCBI Sequence Viewer  
  BAA09522 (Get FASTA)   NCBI Sequence Viewer  
  BAA09523 (Get FASTA)   NCBI Sequence Viewer  
  BAA09524 (Get FASTA)   NCBI Sequence Viewer  
  BAA09525 (Get FASTA)   NCBI Sequence Viewer  
  BAF85396 (Get FASTA)   NCBI Sequence Viewer  
  BAG61935 (Get FASTA)   NCBI Sequence Viewer  
  BAG64576 (Get FASTA)   NCBI Sequence Viewer  
  CAA27544 (Get FASTA)   NCBI Sequence Viewer  
  CBF67662 (Get FASTA)   NCBI Sequence Viewer  
  CBU92536 (Get FASTA)   NCBI Sequence Viewer  
  EAX05872 (Get FASTA)   NCBI Sequence Viewer  
  EAX05873 (Get FASTA)   NCBI Sequence Viewer  
  EAX05874 (Get FASTA)   NCBI Sequence Viewer  
  EAX05875 (Get FASTA)   NCBI Sequence Viewer  
  EAX05876 (Get FASTA)   NCBI Sequence Viewer  
  EAX05877 (Get FASTA)   NCBI Sequence Viewer  
  EAX05878 (Get FASTA)   NCBI Sequence Viewer  
  EAX05879 (Get FASTA)   NCBI Sequence Viewer  
  EAX05880 (Get FASTA)   NCBI Sequence Viewer  
  EAX05881 (Get FASTA)   NCBI Sequence Viewer  
  EAX05882 (Get FASTA)   NCBI Sequence Viewer  
  EAX05883 (Get FASTA)   NCBI Sequence Viewer  
  Q14103 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003810   ⟸   NM_001003810
- Peptide Label: isoform d
- UniProtKB: Q14103 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_112737   ⟸   NM_031369
- Peptide Label: isoform b
- UniProtKB: Q14103 (UniProtKB/Swiss-Prot),   A0A024RDB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_002129   ⟸   NM_002138
- Peptide Label: isoform c
- UniProtKB: Q14103 (UniProtKB/Swiss-Prot),   A0A024RDF4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_112738   ⟸   NM_031370
- Peptide Label: isoform a
- UniProtKB: Q14103 (UniProtKB/Swiss-Prot),   A0A024RDF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000422615   ⟸   ENST00000503822
RefSeq Acc Id: ENSP00000421952   ⟸   ENST00000507010
RefSeq Acc Id: ENSP00000420926   ⟸   ENST00000509263
RefSeq Acc Id: ENSP00000425439   ⟸   ENST00000509107
RefSeq Acc Id: ENSP00000313199   ⟸   ENST00000313899
RefSeq Acc Id: ENSP00000305860   ⟸   ENST00000352301
RefSeq Acc Id: ENSP00000313327   ⟸   ENST00000353341
RefSeq Acc Id: ENSP00000424002   ⟸   ENST00000513584
RefSeq Acc Id: ENSP00000426446   ⟸   ENST00000514671
RefSeq Acc Id: ENSP00000426666   ⟸   ENST00000515432
Protein Domains
CBFNT   RRM

Promoters
RGD ID:6867854
Promoter ID:EPDNEW_H7092
Type:initiation region
Name:HNRNPD_1
Description:heterogeneous nuclear ribonucleoprotein D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38482,373,991 - 82,374,051EPDNEW
RGD ID:6802363
Promoter ID:HG_KWN:48604
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Jurkat,   Lymphoblastoid
Transcripts:UC003HML.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36483,511,511 - 83,512,492 (-)MPROMDB
RGD ID:6802365
Promoter ID:HG_KWN:48605
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000307213,   NM_001003810,   NM_002138,   NM_031369,   NM_031370,   UC010IJR.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36483,513,661 - 83,514,602 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q21.1-21.23(chr4:75453111-84094295)x1 copy number loss See cases [RCV000050786] Chr4:75453111..84094295 [GRCh38]
Chr4:76378321..85015448 [GRCh37]
Chr4:76597345..85234472 [NCBI36]
Chr4:4q21.1-21.23
pathogenic
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3
pathogenic
GRCh38/hg38 4q13.2-21.23(chr4:67869564-85517308)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|See cases [RCV000053294] Chr4:67869564..85517308 [GRCh38]
Chr4:68735282..86438461 [GRCh37]
Chr4:68417877..86657485 [NCBI36]
Chr4:4q13.2-21.23
pathogenic
GRCh38/hg38 4q13.3-22.1(chr4:74031395-90421127)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|See cases [RCV000053296] Chr4:74031395..90421127 [GRCh38]
Chr4:74897112..91342278 [GRCh37]
Chr4:75115976..91561301 [NCBI36]
Chr4:4q13.3-22.1
pathogenic
GRCh38/hg38 4q21.21-22.1(chr4:79575748-92412449)x1 copy number loss See cases [RCV000053297] Chr4:79575748..92412449 [GRCh38]
Chr4:80496902..93333600 [GRCh37]
Chr4:80715926..93552623 [NCBI36]
Chr4:4q21.21-22.1
pathogenic
GRCh38/hg38 4q21.21-21.23(chr4:81061483-83332595)x1 copy number loss See cases [RCV000053298] Chr4:81061483..83332595 [GRCh38]
Chr4:81982637..84253748 [GRCh37]
Chr4:82201661..84472772 [NCBI36]
Chr4:4q21.21-21.23
pathogenic
GRCh38/hg38 4q21.22-21.23(chr4:81733333-83448842)x1 copy number loss See cases [RCV000053299] Chr4:81733333..83448842 [GRCh38]
Chr4:82654487..84369995 [GRCh37]
Chr4:82873511..84589019 [NCBI36]
Chr4:4q21.22-21.23
pathogenic
GRCh38/hg38 4q21.22-21.23(chr4:81802008-83437114)x1 copy number loss See cases [RCV000053300] Chr4:81802008..83437114 [GRCh38]
Chr4:82723161..84358267 [GRCh37]
Chr4:82942185..84577291 [NCBI36]
Chr4:4q21.22-21.23
pathogenic
GRCh38/hg38 4q21.22-21.3(chr4:82248692-86778340)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053319]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053319]|See cases [RCV000053319] Chr4:82248692..86778340 [GRCh38]
Chr4:83169845..87699493 [GRCh37]
Chr4:83388869..87918517 [NCBI36]
Chr4:4q21.22-21.3
pathogenic
GRCh38/hg38 4q21.21-22.3(chr4:80879777-94809447)x1 copy number loss See cases [RCV000134977] Chr4:80879777..94809447 [GRCh38]
Chr4:81800931..95730598 [GRCh37]
Chr4:82019955..95949621 [NCBI36]
Chr4:4q21.21-22.3
pathogenic
GRCh38/hg38 4q21.21-21.22(chr4:79742612-83153725)x1 copy number loss See cases [RCV000135797] Chr4:79742612..83153725 [GRCh38]
Chr4:80663766..84074878 [GRCh37]
Chr4:80882790..84293902 [NCBI36]
Chr4:4q21.21-21.22
uncertain significance
GRCh38/hg38 4q21.21-21.23(chr4:79786514-85832807)x1 copy number loss See cases [RCV000136865] Chr4:79786514..85832807 [GRCh38]
Chr4:80707668..86753960 [GRCh37]
Chr4:80926692..86972984 [NCBI36]
Chr4:4q21.21-21.23
pathogenic
GRCh38/hg38 4q21.21-24(chr4:80427023-100855441)x1 copy number loss See cases [RCV000137269] Chr4:80427023..100855441 [GRCh38]
Chr4:81348177..101776598 [GRCh37]
Chr4:81567201..101995621 [NCBI36]
Chr4:4q21.21-24
pathogenic
GRCh38/hg38 4q21.21-21.23(chr4:80908016-84329610)x1 copy number loss See cases [RCV000137863] Chr4:80908016..84329610 [GRCh38]
Chr4:81829170..85250763 [GRCh37]
Chr4:82048194..85469787 [NCBI36]
Chr4:4q21.21-21.23
likely pathogenic
GRCh38/hg38 4q13.3-21.3(chr4:72262258-86002147)x3 copy number gain See cases [RCV000138312] Chr4:72262258..86002147 [GRCh38]
Chr4:73127975..86923300 [GRCh37]
Chr4:73346839..87142324 [NCBI36]
Chr4:4q13.3-21.3
pathogenic
GRCh38/hg38 4q21.21-21.3(chr4:80043949-86948317)x1 copy number loss See cases [RCV000140416] Chr4:80043949..86948317 [GRCh38]
Chr4:80965103..87869469 [GRCh37]
Chr4:81184127..88088493 [NCBI36]
Chr4:4q21.21-21.3
pathogenic
GRCh38/hg38 4q21.22-21.23(chr4:81675848-83970410)x1 copy number loss See cases [RCV000143321] Chr4:81675848..83970410 [GRCh38]
Chr4:82597002..84891563 [GRCh37]
Chr4:82816026..85110587 [NCBI36]
Chr4:4q21.22-21.23
likely pathogenic
GRCh38/hg38 4q13.2-22.3(chr4:68686088-95294456)x3 copy number gain See cases [RCV000143458] Chr4:68686088..95294456 [GRCh38]
Chr4:69551806..96215607 [GRCh37]
Chr4:69234401..96434630 [NCBI36]
Chr4:4q13.2-22.3
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q21.21-22.1(chr4:82283358-90341831)x1 copy number loss See cases [RCV000447691] Chr4:82283358..90341831 [GRCh37]
Chr4:4q21.21-22.1
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q21.22(chr4:83264510-83454808)x1 copy number loss See cases [RCV000511346] Chr4:83264510..83454808 [GRCh37]
Chr4:4q21.22
uncertain significance
GRCh37/hg19 4q21.22(chr4:83003904-83575588)x1 copy number loss See cases [RCV000511891] Chr4:83003904..83575588 [GRCh37]
Chr4:4q21.22
uncertain significance
GRCh37/hg19 4q21.21-21.23(chr4:82359656-84155605)x1 copy number loss See cases [RCV000511583] Chr4:82359656..84155605 [GRCh37]
Chr4:4q21.21-21.23
likely pathogenic
GRCh37/hg19 4q21.22(chr4:82790850-83567592)x1 copy number loss See cases [RCV000512466] Chr4:82790850..83567592 [GRCh37]
Chr4:4q21.22
uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q21.21-22.3(chr4:81314915-96636651)x1 copy number loss not provided [RCV000682426] Chr4:81314915..96636651 [GRCh37]
Chr4:4q21.21-22.3
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
NM_031370.3(HNRNPD):c.635_638dup (p.Pro214fs) duplication not provided [RCV000762097] Chr4:82357427..82357428 [GRCh38]
Chr4:83278580..83278581 [GRCh37]
Chr4:4q21.22
uncertain significance
GRCh37/hg19 4q13.3-21.23(chr4:72680879-86426232)x1 copy number loss not provided [RCV001005556] Chr4:72680879..86426232 [GRCh37]
Chr4:4q13.3-21.23
pathogenic
GRCh37/hg19 4q21.22-21.23(chr4:82593140-85651685)x1 copy number loss not provided [RCV001005566] Chr4:82593140..85651685 [GRCh37]
Chr4:4q21.22-21.23
pathogenic
GRCh37/hg19 4q21.21-22.1(chr4:82043901-88334228) copy number loss not provided [RCV000767792] Chr4:82043901..88334228 [GRCh37]
Chr4:4q21.21-22.1
pathogenic
GRCh37/hg19 4q21.22(chr4:83026373-83367140)x1 copy number loss not provided [RCV001005567] Chr4:83026373..83367140 [GRCh37]
Chr4:4q21.22
likely pathogenic
GRCh37/hg19 4q21.21-22.1(chr4:80482400-92572499)x1 copy number loss See cases [RCV000790579] Chr4:80482400..92572499 [GRCh37]
Chr4:4q21.21-22.1
pathogenic
GRCh37/hg19 4q21.1-21.23(chr4:78769297-84968832)x1 copy number loss not provided [RCV000846933] Chr4:78769297..84968832 [GRCh37]
Chr4:4q21.1-21.23
pathogenic
GRCh37/hg19 4q21.21-21.22(chr4:80199183-84074906)x1 copy number loss not provided [RCV000848187] Chr4:80199183..84074906 [GRCh37]
Chr4:4q21.21-21.22
pathogenic
null single nucleotide variant not provided [RCV001594749] Chr4:82357625 [GRCh38]
Chr4:83278778 [GRCh37]
Chr4:4q21.22
benign
null single nucleotide variant not provided [RCV001621469] Chr4:82358569 [GRCh38]
Chr4:83279722 [GRCh37]
Chr4:4q21.22
benign
Single allele deletion Chromosome 4q21 deletion syndrome [RCV001172266] Chr4:83196931..85540706 [GRCh37]
Chr4:4q21.22-21.23
pathogenic
null single nucleotide variant not provided [RCV001692675] Chr4:82358578 [GRCh38]
Chr4:83279731 [GRCh37]
Chr4:4q21.22
benign
NM_000085.5(CLCNKB):c.101-50G>C single nucleotide variant not provided [RCV001682406] Chr4:82357762 [GRCh38]
Chr4:83278915 [GRCh37]
Chr4:4q21.22
benign
GRCh37/hg19 4q13.3-21.3(chr4:71412409-87920784)x1 copy number loss See cases [RCV001263040] Chr4:71412409..87920784 [GRCh37]
Chr4:4q13.3-21.3
pathogenic
Single allele duplication not provided [RCV001538205] Chr4:82374065..82374066 [GRCh38]
Chr4:83295218..83295219 [GRCh37]
Chr4:4q21.22
benign
null single nucleotide variant not provided [RCV001667622] Chr4:82355233 [GRCh38]
Chr4:83276386 [GRCh37]
Chr4:4q21.22
benign
NM_000085.5(CLCNKB):c.101-50G>C single nucleotide variant not provided [RCV001679032] Chr4:82371880 [GRCh38]
Chr4:83293033 [GRCh37]
Chr4:4q21.22
benign
null duplication not provided [RCV001619117] Chr4:82355277..82355278 [GRCh38]
Chr4:83276430..83276431 [GRCh37]
Chr4:4q21.22
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5036 AgrOrtholog
COSMIC HNRNPD COSMIC
Ensembl Genes ENSG00000138668 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000305860 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000313199 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000313327 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000420926 UniProtKB/TrEMBL
  ENSP00000421952 UniProtKB/TrEMBL
  ENSP00000422615 UniProtKB/TrEMBL
  ENSP00000424002 UniProtKB/TrEMBL
  ENSP00000425439 UniProtKB/TrEMBL
  ENSP00000426446 UniProtKB/TrEMBL
  ENSP00000426666 UniProtKB/TrEMBL
Ensembl Transcript ENST00000313899 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000352301 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000353341 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000503822 UniProtKB/TrEMBL
  ENST00000507010 UniProtKB/TrEMBL
  ENST00000509107 UniProtKB/TrEMBL
  ENST00000509263 UniProtKB/TrEMBL
  ENST00000513584 UniProtKB/TrEMBL
  ENST00000514671 UniProtKB/TrEMBL
  ENST00000515432 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000138668 GTEx
HGNC ID HGNC:5036 ENTREZGENE
Human Proteome Map HNRNPD Human Proteome Map
InterPro CARG-binding_factor_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 3184 ENTREZGENE
OMIM 601324 OMIM
Pfam CBFNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29361 PharmGKB
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RDB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A024RDF3 ENTREZGENE
  A0A024RDF4 ENTREZGENE, UniProtKB/TrEMBL
  A1LU37_HUMAN UniProtKB/TrEMBL
  D6RAF8_HUMAN UniProtKB/TrEMBL
  D6RBP9_HUMAN UniProtKB/TrEMBL
  D6RBQ9_HUMAN UniProtKB/TrEMBL
  D6RD83_HUMAN UniProtKB/TrEMBL
  D6RF44_HUMAN UniProtKB/TrEMBL
  H0Y8G5_HUMAN UniProtKB/TrEMBL
  H0YA96_HUMAN UniProtKB/TrEMBL
  HNRPD_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A8K9J2 UniProtKB/Swiss-Prot
  P07029 UniProtKB/Swiss-Prot
  Q01858 UniProtKB/Swiss-Prot
  Q14100 UniProtKB/Swiss-Prot
  Q14101 UniProtKB/Swiss-Prot
  Q14102 UniProtKB/Swiss-Prot
  Q4W5A1 UniProtKB/Swiss-Prot
  Q9UCE8 UniProtKB/Swiss-Prot
  Q9UCE9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 HNRNPD  heterogeneous nuclear ribonucleoprotein D  HNRNPD  heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)  Symbol and/or name change 5135510 APPROVED