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Gene: PWP1 (PWP1 homolog, endonuclein) Homo sapiens
Symbol: PWP1
Name: PWP1 homolog, endonuclein
Description: Predicted to have H4K20me3 modified histone binding activity. Involved in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Localizes to the Golgi apparatus and nucleolus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: endonuclein; IEF-SSP-9502; keratinocyte protein IEF SSP 9502; nuclear phosphoprotein similar to S. cerevisiae PWP1; periodic tryptophan protein 1 homolog; PWP1 homolog
Mus musculus (house mouse) : Pwp1 (PWP1 homolog, endonuclein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pwp1 (PWP1 homolog, endonuclein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pwp1 (PWP1 homolog, endonuclein)
Pan paniscus (bonobo/pygmy chimpanzee) : PWP1 (PWP1 homolog, endonuclein)
Canis lupus familiaris (dog) : PWP1 (PWP1 homolog, endonuclein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pwp1 (PWP1 homolog, endonuclein)
Sus scrofa (pig) : PWP1 (PWP1 homolog, endonuclein)
Chlorocebus sabaeus (green monkey) : PWP1 (PWP1 homolog, endonuclein)
Heterocephalus glaber (naked mole-rat) : Pwp1 (PWP1 homolog, endonuclein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12107,685,799 - 107,713,162 (+)Ensembl
GRCh3812107,685,732 - 107,713,162 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712108,079,590 - 108,106,257 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612106,603,720 - 106,630,387 (+)NCBINCBI36hg18NCBI36
Celera12107,745,148 - 107,771,815 (+)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12105,139,992 - 105,166,399 (+)NCBIHuRef
CHM1_112108,045,481 - 108,072,890 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PWP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605095
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.