(+)-pilocarpine increases expression ISO RGD:2366 6480464 Pilocarpine results in increased expression of ABCC2 protein CTD PMID:16504477 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:2366 6480464 epigallocatechin gallate results in decreased expression of ABCC2 protein CTD PMID:23146761 (2,4,5-trichlorophenoxy)acetic acid increases expression EXP 6480464 2 more ... CTD PMID:10377250 , PMID:16426233 (2,4,5-trichlorophenoxy)acetic acid multiple interactions ISO RGD:10368 6480464 Alpha-Amanitin inhibits the reaction [2 more ... CTD PMID:10377250 (2,4,5-trichlorophenoxy)acetic acid increases expression ISO RGD:10368 6480464 2 more ... CTD PMID:10377250 , PMID:16426233 (RS)-coclaurine multiple interactions ISO RGD:10368 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 (RS)-norcoclaurine multiple interactions ISO RGD:10368 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 (S)-coclaurine multiple interactions ISO RGD:10368 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 (S)-colchicine multiple interactions ISO RGD:2366 6480464 [Colchicine co-treated with JTE 013] inhibits the reaction [Taurolithocholic Acid results in decreased activity of ABCC2 protein] CTD PMID:31300867 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of ABCC2 mRNA CTD PMID:24464585 1,2-dichloroethane decreases expression ISO RGD:10368 6480464 ethylene dichloride results in decreased expression of ABCC2 mRNA CTD PMID:28960355 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile increases expression EXP 6480464 Citalopram results in increased expression of ABCC2 protein CTD PMID:12524417 1-chloro-2,4-dinitrobenzene decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Dinitrochlorobenzene CTD PMID:26049102 1-naphthyl isothiocyanate increases response to substance ISO RGD:10368 6480464 ABCC2 results in increased susceptibility to 1-Naphthylisothiocyanate CTD PMID:20551477 1-naphthyl isothiocyanate decreases expression ISO RGD:10368 6480464 1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA, 1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein CTD PMID:30517764 , PMID:32579994 1-naphthyl isothiocyanate increases expression ISO RGD:2366 6480464 1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA, 1-Naphthylisothiocyanate results in increased expression of ABCC2 protein CTD PMID:27317372 , PMID:27765674 1-naphthyl isothiocyanate increases expression ISO RGD:10368 6480464 1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA, 1-Naphthylisothiocyanate results in increased expression of ABCC2 protein CTD PMID:25655198 , PMID:29660435 1-naphthyl isothiocyanate multiple interactions ISO RGD:10368 6480464 alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA] more ... CTD PMID:25655198 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:2366 6480464 dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA] more ... CTD PMID:25418378 more ... 1-naphthyl isothiocyanate decreases expression ISO RGD:2366 6480464 1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA, 1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein CTD PMID:25380136 more ... 17alpha-ethynylestradiol increases uptake EXP 6480464 ABCC2 protein results in increased uptake of Ethinyl Estradiol metabolite CTD PMID:14722317 17alpha-ethynylestradiol decreases expression ISO RGD:2366 15090804 17alpha-ethynylestradiol decreases expression of Abcc2 mRNA and protein in primary hepatocytes, decreases expression of mRNA in liver RGD 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ABCC2 mRNA CTD PMID:27743861 17alpha-ethynylestradiol multiple interactions ISO RGD:10368 6480464 SRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA], SRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein] CTD PMID:27818225 17alpha-ethynylestradiol decreases expression ISO RGD:10368 6480464 Ethinyl Estradiol results in decreased expression of ABCC2 mRNA, Ethinyl Estradiol results in decreased expression of ABCC2 protein CTD PMID:27818225 17alpha-ethynylestradiol decreases expression ISO RGD:2366 6480464 Ethinyl Estradiol results in decreased expression of ABCC2 mRNA, Ethinyl Estradiol results in decreased expression of ABCC2 protein CTD PMID:16554369 more ... 17alpha-ethynylestradiol multiple interactions ISO RGD:2366 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA] more ... CTD PMID:15843489 more ... 17alpha-ethynylestradiol affects localization ISO RGD:2366 6480464 Ethinyl Estradiol affects the localization of ABCC2 protein CTD PMID:17681005 17alpha-ethynylestradiol multiple interactions EXP 6480464 Ethinyl Estradiol metabolite promotes the reaction [ABCC2 protein results in increased uptake of estradiol-17 beta-glucuronide] more ... CTD PMID:14722317 more ... 17beta-estradiol affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Estradiol CTD PMID:15507541 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ABCC2 mRNA, Estradiol results in increased expression of ABCC2 protein CTD PMID:19580841 17beta-estradiol multiple interactions ISO RGD:2366 6480464 Estradiol affects the localization of and affects the activity of ABCC2 protein CTD PMID:15374814 17beta-estradiol 17-glucosiduronic acid affects export EXP 6480464 ABCC2 protein affects the export of estradiol-17 beta-glucuronide CTD PMID:15652233 , PMID:15901800 17beta-estradiol 17-glucosiduronic acid decreases secretion ISO RGD:2366 6480464 estradiol-17 beta-glucuronide results in decreased secretion of ABCC2 protein CTD PMID:29090346 17beta-estradiol 17-glucosiduronic acid affects localization ISO RGD:2366 6480464 estradiol-17 beta-glucuronide affects the localization of ABCC2 protein CTD PMID:12029626 more ... 17beta-estradiol 17-glucosiduronic acid affects transport EXP 6480464 ABCC2 protein affects the transport of estradiol-17 beta-glucuronide CTD PMID:11500505 more ... 17beta-estradiol 17-glucosiduronic acid multiple interactions ISO RGD:2366 6480464 abietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide] more ... CTD PMID:12029626 more ... 17beta-estradiol 17-glucosiduronic acid increases transport ISO RGD:2366 6480464 ABCC2 protein modified form results in increased transport of estradiol-17 beta-glucuronide, ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide CTD PMID:15904671 , PMID:18436619 17beta-estradiol 17-glucosiduronic acid affects response to substance ISO RGD:2366 6480464 ABCC2 protein affects the susceptibility to estradiol-17 beta-glucuronide CTD PMID:12702498 17beta-estradiol 17-glucosiduronic acid affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of estradiol-17 beta-glucuronide CTD PMID:12642476 , PMID:15904671 17beta-estradiol 17-glucosiduronic acid multiple interactions EXP 6480464 [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide more ... CTD PMID:12702717 more ... 17beta-estradiol 3-benzoate increases methylation ISO RGD:2366 6480464 estradiol 3-benzoate results in increased methylation of ABCC2 promoter CTD PMID:27415467 2',3'-dideoxyadenosine multiple interactions ISO RGD:2366 6480464 Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-4-6-bromobenzo1 more ... CTD PMID:25813982 , PMID:31300867 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:10368 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:10368 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10368 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ABCC2 mRNA more ... CTD PMID:15833929 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:2366 6480464 Tetrachlorodibenzodioxin affects the expression of ABCC2 mRNA CTD PMID:28341572 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10368 6480464 Tetrachlorodibenzodioxin results in increased expression of ABCC2 mRNA CTD PMID:15833929 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:2366 6480464 Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of ABCC2 protein CTD PMID:22472606 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2366 6480464 Tetrachlorodibenzodioxin results in increased expression of ABCC2 protein CTD PMID:21048045 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10368 6480464 Tetrachlorodibenzodioxin affects the expression of ABCC2 mRNA CTD PMID:21570461 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:10368 6480464 2 more ... CTD PMID:24713691 , PMID:25768209 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:2366 6480464 2 more ... CTD PMID:32109520 2,4,6-trinitrobenzenesulfonic acid decreases expression ISO RGD:2366 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA, Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein CTD PMID:12044520 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate] CTD PMID:16636798 2-acetamidofluorene increases expression ISO RGD:10368 6480464 2-Acetylaminofluorene results in increased expression of ABCC2 mRNA CTD PMID:16381673 , PMID:16426233 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of ABCC2 mRNA, 2-Acetylaminofluorene results in increased expression of ABCC2 protein CTD PMID:10691972 , PMID:16426233 2-acetamidofluorene multiple interactions ISO RGD:10368 6480464 NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA] CTD PMID:16381673 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA, 2-tert-butylhydroquinone results in increased expression of ABCC2 protein CTD PMID:11836020 2-tert-butylhydroquinone increases expression ISO RGD:2366 6480464 2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA CTD PMID:11264000 3',4',7-trihydroxyisoflavone multiple interactions EXP 6480464 3' more ... CTD PMID:22914566 3',4',7-trihydroxyisoflavone decreases expression EXP 6480464 3' more ... CTD PMID:22914566 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:10368 6480464 [3 more ... CTD PMID:15833929 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:2366 6480464 3 more ... CTD PMID:32119087 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:10368 6480464 3 more ... CTD PMID:15833929 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of 2-amino-3-methylimidazo4, 5-fquinoline CTD PMID:16611851 4'-epidoxorubicin multiple interactions EXP 6480464 3' more ... CTD PMID:22914566 , PMID:23867903 4'-epidoxorubicin increases expression EXP 6480464 Epirubicin analog results in increased expression of ABCC2 mRNA, Epirubicin results in increased expression of ABCC2 mRNA CTD PMID:22914566 more ... 4,4'-diaminodiphenylmethane decreases expression ISO RGD:2366 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of ABCC2 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol increases expression ISO RGD:10368 6480464 bis4-hydroxyphenylsulfone results in increased expression of ABCC2 mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one affects abundance ISO RGD:2366 6480464 ABCC2 protein affects the abundance of 4-N-methyl-N-nitrosamino-1-3-pyridyl-1-butanone metabolite CTD PMID:17724374 4-hydroxynon-2-enal multiple interactions EXP 6480464 4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2' more ... CTD PMID:19326901 4-hydroxynon-2-enal affects export ISO RGD:2366 6480464 ABCC2 protein affects the export of 4-hydroxy-2-nonenal metabolite CTD PMID:12623073 5(6)-carboxy-2',7'-dichlorofluorescein increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein CTD PMID:24907646 5(6)-carboxy-2',7'-dichlorofluorescein multiple interactions EXP 6480464 4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2' more ... CTD PMID:19326901 more ... 5(6)-carboxy-2',7'-dichlorofluorescein increases export EXP 6480464 ABCC2 protein results in increased export of 56-carboxy-2' more ... CTD PMID:25862123 , PMID:27450509 5(6)-carboxy-2',7'-dichlorofluorescein multiple interactions ISO RGD:2366 6480464 [ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 56-carboxy-2' more ... CTD PMID:23562342 more ... 5(6)-carboxy-2',7'-dichlorofluorescein increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of 56-carboxy-2', 7'-dichlorofluorescein CTD PMID:24909372 5(6)-carboxy-2',7'-dichlorofluorescein affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of 56-carboxy-2', 7'-dichlorofluorescein CTD PMID:21240898 , PMID:21341280 5(6)-carboxy-2',7'-dichlorofluorescein increases transport EXP 6480464 ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein CTD PMID:24973091 , PMID:31348918 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of ABCC2 mRNA CTD PMID:11509559 5-chloromethylfluorescein diacetate multiple interactions EXP 6480464 ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione] CTD PMID:16049127 5-fluorouracil affects response to substance EXP 6480464 ABCC2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 5-formyltetrahydrofolic acid multiple interactions ISO RGD:2366 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of ABCC2 protein] CTD PMID:16925582 5-methoxypsoralen decreases expression EXP 6480464 5-methoxypsoralen results in decreased expression of ABCC2 mRNA CTD PMID:29079042 5-methoxypsoralen multiple interactions EXP 6480464 [5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin more ... CTD PMID:29079042 5-methoxypsoralen decreases activity EXP 6480464 5-methoxypsoralen results in decreased activity of ABCC2 protein CTD PMID:29079042 6-bromoindirubin-3'-oxime increases expression EXP 6480464 6-bromoindirubin-3'-oxime results in increased expression of ABCC2 mRNA, 6-bromoindirubin-3'-oxime results in increased expression of ABCC2 protein CTD PMID:18624906 6-carboxyfluorescein affects export EXP 6480464 ABCC2 protein affects the export of 6-carboxyfluorescein CTD PMID:11477083 6-carboxyfluorescein multiple interactions EXP 6480464 Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein] CTD PMID:11477083 6-propyl-2-thiouracil increases expression ISO RGD:2366 6480464 Propylthiouracil results in increased expression of ABCC2 mRNA CTD PMID:24780913 8-(4-chlorophenylthio)-cAMP increases expression ISO RGD:10368 6480464 8-4-chlorophenylthiocyclic-3', 5'-AMP results in increased expression of ABCC2 mRNA CTD PMID:27160211 8-Br-cAMP multiple interactions ISO RGD:2366 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA] CTD PMID:27743861 abietic acid multiple interactions ISO RGD:2366 6480464 abietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:18436619 acadesine decreases expression ISO RGD:2366 15090804 acadesine decreases expression of Abcc2 mRNA in primary hepatocytes RGD acetamide decreases expression ISO RGD:2366 6480464 acetamide results in decreased expression of ABCC2 mRNA CTD PMID:31881176 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA] CTD PMID:26049102 actinomycin D multiple interactions ISO RGD:2366 6480464 Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA] CTD PMID:11408547 actinomycin D decreases response to substance ISO RGD:2366 6480464 ABCC2 protein results in decreased susceptibility to Dactinomycin CTD PMID:11455017 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of ABCC2 protein CTD PMID:20106945 aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of ABCC2 gene CTD PMID:27153756 aflatoxin B1 multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCC2 protein more ... CTD PMID:23402939 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of ABCC2 mRNA, Aflatoxin B1 results in increased expression of ABCC2 protein CTD PMID:23402939 AICA ribonucleotide decreases expression ISO RGD:2366 6480464 AICA ribonucleotide results in decreased expression of ABCC2 mRNA CTD PMID:27090119 aldehydo-D-glucose multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-2 more ... CTD PMID:19782883 alfacalcidol increases expression ISO RGD:10368 6480464 alfacalcidol results in increased expression of ABCC2 mRNA CTD PMID:19581390 all-trans-retinoic acid decreases expression ISO RGD:10368 6480464 Tretinoin results in decreased expression of ABCC2 mRNA CTD PMID:16604517 all-trans-retinoic acid multiple interactions ISO RGD:10368 6480464 Tretinoin inhibits the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein], Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]] CTD PMID:29964319 allyl alcohol increases expression ISO RGD:10368 6480464 allyl alcohol results in increased expression of ABCC2 protein CTD PMID:19371622 alpha-amanitin multiple interactions ISO RGD:10368 6480464 Alpha-Amanitin inhibits the reaction [2 more ... CTD PMID:10377250 aluminium hydroxide decreases expression ISO RGD:2366 6480464 Aluminum Hydroxide results in decreased expression of ABCC2 protein CTD PMID:14976346 amiodarone increases expression ISO RGD:2366 6480464 Amiodarone results in increased expression of ABCC2 mRNA CTD PMID:27765674 angelicin decreases expression ISO RGD:2366 6480464 angelicin results in decreased expression of ABCC2 mRNA, angelicin results in decreased expression of ABCC2 protein CTD PMID:30597224 Aroclor 1254 increases expression ISO RGD:2366 6480464 Chlorodiphenyl 54% Chlorine results in increased expression of ABCC2 mRNA CTD PMID:22659317 arsane increases transport EXP 6480464 ABCC2 protein results in increased transport of Arsenic CTD PMID:25752797 arsane increases expression EXP 6480464 Arsenic results in increased expression of ABCC2 protein CTD PMID:25752797 arsane increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of Arsenic CTD PMID:25752797 arsenic atom increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of Arsenic CTD PMID:25752797 arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of ABCC2 protein CTD PMID:25752797 arsenic atom increases transport EXP 6480464 ABCC2 protein results in increased transport of Arsenic CTD PMID:25752797 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of ABCC2 mRNA, arsenite results in increased expression of ABCC2 protein CTD PMID:11836020 arsenite(3-) increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of arsenite CTD PMID:17467962 arsenous acid decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21783896 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ABCC2 mRNA, Arsenic Trioxide results in increased expression of ABCC2 protein CTD PMID:21945491 , PMID:27736728 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of ABCC2 mRNA, Arsenic Trioxide results in decreased expression of ABCC2 protein CTD PMID:21945491 , PMID:22214486 atazanavir sulfate decreases expression EXP 6480464 Atazanavir Sulfate results in decreased expression of ABCC2 mRNA CTD PMID:32152650 atorvastatin calcium decreases activity EXP 6480464 Atorvastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 atorvastatin calcium decreases activity ISO RGD:2366 6480464 Atorvastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 atorvastatin calcium multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of Atorvastatin analog more ... CTD PMID:15616150 , PMID:23562342 atorvastatin calcium increases expression ISO RGD:10368 6480464 Atorvastatin results in increased expression of ABCC2 mRNA CTD PMID:25278499 atorvastatin calcium multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of Atorvastatin analog more ... CTD PMID:15616150 , PMID:23562342 ATP multiple interactions ISO RGD:2366 6480464 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3], Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat] CTD PMID:9067317 , PMID:9794919 ATP affects activity EXP 6480464 Adenosine Triphosphate affects the activity of ABCC2 protein CTD PMID:32472168 ATP multiple interactions EXP 6480464 [Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite more ... CTD PMID:24039982 more ... ATP affects metabolic processing EXP 6480464 ABCC2 protein affects the metabolism of Adenosine Triphosphate CTD PMID:22027652 ATP multiple interactions ISO RGD:10368 6480464 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1, 2-dichlorovinyl-N-acetylcysteine] CTD PMID:20060011 azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of ABCC2 mRNA CTD PMID:22623647 azathioprine increases expression ISO RGD:2366 6480464 Azathioprine results in increased expression of ABCC2 mRNA CTD PMID:27765674 aztreonam increases expression ISO RGD:10368 6480464 Aztreonam results in increased expression of ABCC2 mRNA CTD PMID:24657338 benzbromarone multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-2 more ... CTD PMID:19782883 , PMID:19853032 benzbromarone multiple interactions EXP 6480464 Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:31348918 benzbromarone decreases activity EXP 6480464 Benzbromarone results in decreased activity of ABCC2 protein CTD PMID:22646477 benzo[a]pyrene increases expression ISO RGD:10368 6480464 Benzoapyrene results in increased expression of ABCC2 mRNA CTD PMID:19770486 , PMID:21715664 benzo[a]pyrene decreases expression EXP 6480464 Benzoapyrene results in decreased expression of ABCC2 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation EXP 6480464 Benzoapyrene results in increased methylation of ABCC2 exon, Benzoapyrene results in increased methylation of ABCC2 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:10368 6480464 Benzoapyrene results in increased methylation of ABCC2 exon, Benzoapyrene results in increased methylation of ABCC2 intron CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzoapyrene results in increased expression of ABCC2 mRNA CTD PMID:21632981 more ... benzo[a]pyrene increases transport ISO RGD:10368 6480464 ABCC2 protein results in increased transport of Benzoapyrene, ABCC2 protein results in increased transport of Benzoapyrene metabolite CTD PMID:25451572 benzoylaconine multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylaconine CTD PMID:23200901 benzoylhypaconine multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylhypaconine CTD PMID:23200901 benzoylmesaconine multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylmesaconine CTD PMID:23200901 benzylpenicillin increases activity ISO RGD:2366 6480464 Penicillin G results in increased activity of ABCC2 protein CTD PMID:15904671 benzylpenicillin multiple interactions EXP 6480464 Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12702717 beta-hexachlorocyclohexane increases expression ISO RGD:10368 6480464 beta-hexachlorocyclohexane results in increased expression of ABCC2 mRNA CTD PMID:28392238 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of ABCC2 mRNA CTD PMID:16426233 more ... beta-naphthoflavone decreases expression ISO RGD:2366 6480464 beta-Naphthoflavone results in decreased expression of ABCC2 mRNA CTD PMID:20607812 beta-naphthoflavone increases expression ISO RGD:2366 6480464 beta-Naphthoflavone results in increased expression of ABCC2 mRNA CTD PMID:11752103 beta-naphthoflavone increases expression ISO RGD:10368 6480464 beta-Naphthoflavone results in increased expression of ABCC2 mRNA CTD PMID:15833929 , PMID:16426233 beta-naphthoflavone multiple interactions ISO RGD:10368 6480464 [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA CTD PMID:15833929 bezafibrate affects localization EXP 6480464 Bezafibrate affects the localization of ABCC2 protein CTD PMID:15258199 bezafibrate multiple interactions ISO RGD:10368 6480464 [Sodium Glutamate co-treated with Bezafibrate] results in increased expression of ABCC2 mRNA CTD PMID:21549692 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of ABCC2 mRNA CTD PMID:15258199 bilirubin IXalpha decreases activity ISO RGD:2366 6480464 Bilirubin results in decreased activity of ABCC2 protein CTD PMID:15901347 bilirubin IXalpha multiple interactions ISO RGD:2366 6480464 Bilirubin analog inhibits the reaction [tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein] CTD PMID:24306262 bilirubin IXalpha affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Bilirubin CTD PMID:15374814 biochanin A multiple interactions EXP 6480464 biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] CTD PMID:15955639 bis(2-ethylhexyl) phthalate increases expression ISO RGD:2366 6480464 Diethylhexyl Phthalate results in increased expression of ABCC2 mRNA CTD PMID:11752103 bisdemethoxycurcumin decreases activity EXP 6480464 bis4-hydroxycinnamoylmethane results in decreased activity of ABCC2 protein CTD PMID:15885658 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ABCC2 mRNA, bisphenol A results in increased expression of ABCC2 protein CTD PMID:18634814 bisphenol A affects expression ISO RGD:2366 6480464 bisphenol A affects the expression of ABCC2 mRNA CTD PMID:30903817 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ABCC2 mRNA CTD PMID:30903817 bisphenol A affects methylation ISO RGD:2366 6480464 bisphenol A affects the methylation of ABCC2 promoter CTD PMID:27415467 bisphenol A decreases expression ISO RGD:2366 6480464 bisphenol A results in decreased expression of ABCC2 mRNA CTD PMID:25181051 Boldine increases expression ISO RGD:2366 6480464 boldine results in increased expression of ABCC2 mRNA CTD PMID:25771127 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of ABCC2 mRNA CTD PMID:21215737 bosentan increases expression ISO RGD:2366 6480464 bosentan results in increased expression of ABCC2 mRNA CTD PMID:27765674 bosentan increases expression EXP 6480464 Bosentan results in increased expression of ABCC2 mRNA CTD PMID:29761207 bosentan decreases expression EXP 6480464 bosentan results in decreased expression of ABCC2 mRNA CTD PMID:28369585 bromfenac decreases activity EXP 6480464 bromfenac results in decreased activity of ABCC2 protein CTD PMID:22646477 bromosulfophthalein affects export EXP 6480464 ABCC2 protein affects the export of Sulfobromophthalein CTD PMID:16046661 bucladesine increases expression EXP 6480464 Bucladesine results in increased expression of ABCC2 mRNA, Bucladesine results in increased expression of ABCC2 protein CTD PMID:26049102 bucladesine affects localization ISO RGD:2366 6480464 Bucladesine affects the localization of ABCC2 protein CTD PMID:29052767 bucladesine increases activity EXP 6480464 Bucladesine results in increased activity of ABCC2 protein CTD PMID:29052767 bucladesine multiple interactions ISO RGD:2366 6480464 Bucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein], KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein] CTD PMID:12029626 , PMID:29052767 bucladesine multiple interactions EXP 6480464 Bucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter] more ... CTD PMID:26049102 , PMID:29052767 buspirone decreases expression ISO RGD:2366 6480464 Buspirone results in decreased expression of ABCC2 mRNA CTD PMID:24136188 buta-1,3-diene decreases expression ISO RGD:10368 6480464 1, 3-butadiene results in decreased expression of ABCC2 mRNA CTD PMID:29038090 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of ABCC2 mRNA CTD PMID:26079696 butylated hydroxyanisole increases expression EXP 6480464 Butylated Hydroxyanisole results in increased expression of ABCC2 mRNA CTD PMID:16426233 butylated hydroxyanisole multiple interactions ISO RGD:10368 6480464 [Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA CTD PMID:15833929 butylated hydroxyanisole increases expression ISO RGD:10368 6480464 Butylated Hydroxyanisole results in increased expression of ABCC2 mRNA, Butylated Hydroxyanisole results in increased expression of ABCC2 protein CTD PMID:15833929 , PMID:16426233 cadmium dichloride decreases methylation ISO RGD:2366 6480464 Cadmium Chloride results in decreased methylation of ABCC2 promoter CTD PMID:22457795 cadmium dichloride decreases expression ISO RGD:2366 6480464 Cadmium Chloride results in decreased expression of ABCC2 mRNA CTD PMID:25993096 cadmium dichloride increases expression ISO RGD:10368 6480464 Cadmium Chloride results in increased expression of ABCC2 CTD PMID:22914987 cadmium dichloride multiple interactions ISO RGD:10368 6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form] inhibits the reaction [Cadmium Chloride results in increased expression of ABCC2] CTD PMID:22914987 caffeine multiple interactions ISO RGD:10368 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 calcein affects export EXP 6480464 ABCC2 protein affects the export of fluorexon CTD PMID:15670588 calcein increases abundance EXP 6480464 ABCC2 protein alternative form results in increased abundance of fluorexon CTD PMID:22027652 calcein multiple interactions EXP 6480464 robinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon] CTD PMID:15670588 calcein affects transport EXP 6480464 ABCC2 protein affects the transport of fluorexon CTD PMID:15848949 calcein am affects transport EXP 6480464 ABCC2 protein affects the transport of calcein AM CTD PMID:15210835 calcein am increases export EXP 6480464 ABCC2 protein results in increased export of calcein AM CTD PMID:19952419 calcein am multiple interactions ISO RGD:2366 6480464 Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] more ... CTD PMID:15616150 calcein am increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of calcein AM CTD PMID:15616150 calcein am multiple interactions EXP 6480464 [MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM more ... CTD PMID:15616150 more ... calcein am increases transport EXP 6480464 ABCC2 protein results in increased transport of calcein AM CTD PMID:15616150 , PMID:19647055 calcitriol increases expression ISO RGD:2366 6480464 Calcitriol results in increased expression of ABCC2 protein CTD PMID:21240898 , PMID:21341280 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of ABCC2 mRNA CTD PMID:27107558 calcitriol increases activity ISO RGD:2366 6480464 Calcitriol results in increased activity of ABCC2 protein CTD PMID:21240898 , PMID:21341280 calcium atom multiple interactions EXP 6480464 Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:25862123 calcium(0) multiple interactions EXP 6480464 Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:25862123 captan multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with 2-chloro-N-4-chlorobiphenyl-2-ylnicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of ABCC2 mRNA, Carbamazepine results in increased expression of ABCC2 protein CTD PMID:15371980 , PMID:17112801 carbamazepine increases transport EXP 6480464 ABCC2 protein results in increased transport of Carbamazepine CTD PMID:20216337 carbamazepine multiple interactions ISO RGD:2366 6480464 KN 62 inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein], Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein] CTD PMID:18473823 carbamazepine affects response to substance EXP 6480464 ABCC2 gene SNP affects the susceptibility to Carbamazepine CTD PMID:20216337 carbon monoxide increases activity ISO RGD:2366 6480464 Carbon Monoxide results in increased activity of ABCC2 protein CTD PMID:13678533 carboplatin decreases expression EXP 6480464 Carboplatin results in decreased expression of ABCC2 mRNA, Carboplatin results in decreased expression of ABCC2 protein CTD PMID:27692344 carmustine affects response to substance EXP 6480464 ABCC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 cefaloridine increases expression ISO RGD:2366 6480464 Cephaloridine results in increased expression of ABCC2 mRNA CTD PMID:18500788 cefalotin multiple interactions ISO RGD:10368 6480464 [Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA CTD PMID:24657338 celecoxib decreases activity EXP 6480464 Celecoxib results in decreased activity of ABCC2 protein CTD PMID:22646477 cerivastatin affects export EXP 6480464 ABCC2 protein affects the export of cerivastatin CTD PMID:15901800 chenodeoxycholic acid increases expression EXP 6480464 Chenodeoxycholic Acid results in increased expression of ABCC2 mRNA CTD PMID:25055961 chenodeoxycholic acid increases expression ISO RGD:10368 6480464 Chenodeoxycholic Acid results in increased expression of ABCC2 mRNA CTD PMID:25582706 chenodeoxycholic acid affects expression ISO RGD:2366 6480464 Chenodeoxycholic Acid affects the expression of ABCC2 mRNA CTD PMID:20888898 chenodeoxycholic acid multiple interactions ISO RGD:2366 6480464 ABCC2 protein affects the reaction [verlukast results in decreased secretion of Chenodeoxycholic Acid] more ... CTD PMID:21262925 , PMID:27743861 chlorambucil affects export EXP 6480464 ABCC2 protein affects the export of Chlorambucil analog CTD PMID:14569069 chlorambucil multiple interactions EXP 6480464 ABCC2 protein promotes the reaction [GSTA1 protein results in decreased susceptibility to Chlorambucil] CTD PMID:14569069 chlordecone decreases activity EXP 6480464 Chlordecone results in decreased activity of ABCC2 protein CTD PMID:24464585 chlorogenic acid multiple interactions ISO RGD:10368 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein] CTD PMID:25043994 chloroquine decreases expression EXP 6480464 Chloroquine results in decreased expression of ABCC2 mRNA, Chloroquine results in decreased expression of ABCC2 protein CTD PMID:27692344 chlorpromazine increases expression ISO RGD:2366 6480464 Chlorpromazine results in increased expression of ABCC2 mRNA CTD PMID:27765674 chlorpyrifos multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with 2-chloro-N-4-chlorobiphenyl-2-ylnicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 cholic acid increases expression EXP 6480464 Cholic Acid results in increased expression of ABCC2 mRNA CTD PMID:25055961 cholic acid increases expression ISO RGD:10368 6480464 Cholic Acid results in increased expression of ABCC2 mRNA, Cholic Acid results in increased expression of ABCC2 protein CTD PMID:11438506 more ... choline multiple interactions ISO RGD:10368 6480464 [LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA, [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA CTD PMID:24384915 choline multiple interactions ISO RGD:2366 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA, [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 protein CTD PMID:17640958 , PMID:24384915 chrysin increases expression EXP 6480464 chrysin results in increased expression of ABCC2 protein CTD PMID:20457140 chrysin decreases activity EXP 6480464 chrysin results in decreased activity of ABCC2 protein CTD PMID:20457140 chrysin multiple interactions EXP 6480464 [chrysin results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan, chrysin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] CTD PMID:15955639 , PMID:20457140 chrysophanol increases expression ISO RGD:2366 6480464 chrysophanic acid results in increased expression of ABCC2 mRNA, chrysophanic acid results in increased expression of ABCC2 protein CTD PMID:28161596 ciprofloxacin decreases expression ISO RGD:10368 6480464 Ciprofloxacin results in decreased expression of ABCC2 mRNA CTD PMID:24657338 cisplatin multiple interactions ISO RGD:10368 6480464 [Luteolin co-treated with Cisplatin] results in increased expression of ABCC2 protein more ... CTD PMID:20605904 more ... cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ABCC2 mRNA, Cisplatin results in increased expression of ABCC2 protein CTD PMID:26721606 , PMID:27392435 cisplatin decreases expression ISO RGD:2366 6480464 Cisplatin results in decreased expression of ABCC2 mRNA CTD PMID:26739623 cisplatin multiple interactions ISO RGD:2366 6480464 formononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA] more ... CTD PMID:22992436 more ... cisplatin increases expression ISO RGD:2366 6480464 Cisplatin results in increased expression of ABCC2 mRNA, Cisplatin results in increased expression of ABCC2 protein CTD PMID:22023808 more ... cisplatin decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Cisplatin CTD PMID:15688364 more ... cisplatin increases response to substance ISO RGD:10368 6480464 ABCC2 gene mutant form results in increased susceptibility to Cisplatin CTD PMID:24641901 cisplatin decreases response to substance ISO RGD:2366 6480464 ABCC2 protein results in decreased susceptibility to Cisplatin CTD PMID:11455017 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of ABCC2 mRNA more ... CTD PMID:18695918 more ... cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of ABCC2, Cisplatin results in decreased expression of ABCC2 mRNA CTD PMID:20737486 , PMID:21905038 cisplatin affects export EXP 6480464 ABCC2 protein affects the export of Cisplatin CTD PMID:15985617 cisplatin affects response to substance EXP 6480464 ABCC2 affects the susceptibility to Cisplatin CTD PMID:15756446 cisplatin increases expression ISO RGD:10368 6480464 Cisplatin results in increased expression of ABCC2 mRNA, Cisplatin results in increased expression of ABCC2 protein CTD PMID:20605904 more ... citalopram increases expression EXP 6480464 Citalopram results in increased expression of ABCC2 protein CTD PMID:12524417 clobazam affects response to substance ISO RGD:2366 6480464 ABCC2 protein affects the susceptibility to clobazam CTD PMID:22982618 clofibrate increases expression ISO RGD:10368 6480464 Clofibrate results in increased expression of ABCC2 mRNA CTD PMID:22496397 , PMID:28973556 clofibrate decreases expression ISO RGD:2366 6480464 Clofibrate results in decreased expression of ABCC2 mRNA CTD PMID:11328961 , PMID:19224547 clofibric acid decreases expression ISO RGD:2366 6480464 Clofibric Acid results in decreased expression of ABCC2 protein CTD PMID:15908472 clotrimazole increases expression EXP 6480464 Clotrimazole results in increased expression of ABCC2 mRNA, Clotrimazole results in increased expression of ABCC2 protein CTD PMID:11836020 colforsin daropate hydrochloride increases expression EXP 6480464 Colforsin results in increased expression of ABCC2 mRNA, Colforsin results in increased expression of ABCC2 protein CTD PMID:19580841 , PMID:26049102 coniferyl aldehyde increases expression EXP 6480464 coniferaldehyde results in increased expression of ABCC2 mRNA CTD PMID:26275128 copper atom multiple interactions EXP 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA CTD PMID:25167922 copper(0) multiple interactions EXP 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA CTD PMID:25167922 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of ABCC2 mRNA CTD PMID:19549813 curcumin decreases activity EXP 6480464 Curcumin results in decreased activity of ABCC2 protein CTD PMID:15885658 cyazofamid increases uptake EXP 6480464 ABCC2 protein results in increased uptake of cyazofamid CTD PMID:32003934 cyclosporin A multiple interactions EXP 6480464 [Cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo4 more ... CTD PMID:16356829 more ... cyclosporin A decreases activity EXP 6480464 Cyclosporine results in decreased activity of ABCC2 protein CTD PMID:15618715 more ... cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of ABCC2 mRNA CTD PMID:25562108 , PMID:32253466 cyclosporin A increases expression ISO RGD:2366 6480464 Cyclosporine results in increased expression of ABCC2 mRNA CTD PMID:21865292 , PMID:27765674 cyclosporin A decreases activity ISO RGD:2366 6480464 Cyclosporine results in decreased activity of ABCC2 protein CTD PMID:15618715 cyclosporin A decreases expression ISO RGD:2366 6480464 Cyclosporine results in decreased expression of ABCC2 mRNA CTD PMID:11589784 cyclosporin A multiple interactions ISO RGD:2366 6480464 Cyclosporine inhibits the reaction [ABCC2 protein affects the transport of mycophenolic acid glucuronide], Cyclosporine inhibits the reaction [ABCC2 protein results in increased secretion of Fluo-3] CTD PMID:15816878 , PMID:9794919 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of ABCC2 mRNA CTD PMID:20106945 cyclosporin A affects expression EXP 6480464 Cyclosporine affects the expression of ABCC2 mRNA CTD PMID:24973091 cyproconazole increases expression ISO RGD:10368 6480464 cyproconazole results in increased expression of ABCC2 mRNA CTD PMID:28058446 cyproconazole multiple interactions ISO RGD:2366 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA CTD PMID:29038839 D-glucose multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-2 more ... CTD PMID:19782883 dapsone decreases expression ISO RGD:2366 6480464 Dapsone metabolite results in decreased expression of ABCC2 protein CTD PMID:15863252 daunorubicin affects response to substance EXP 6480464 ABCC2 affects the susceptibility to Daunorubicin CTD PMID:18451141 daunorubicin multiple interactions EXP 6480464 [5-Methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin more ... CTD PMID:29079042 DDE increases expression ISO RGD:10368 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of ABCC2 mRNA CTD PMID:28392238 DDT increases expression EXP 6480464 DDT results in increased expression of ABCC2 mRNA CTD PMID:24464585 , PMID:31521043 demethoxycurcumin decreases activity EXP 6480464 demethoxycurcumin results in decreased activity of ABCC2 protein CTD PMID:15885658 deoxycholic acid multiple interactions ISO RGD:10368 6480464 SLCO1A1 protein affects the susceptibility to [Deoxycholic Acid affects the expression of ABCC2 mRNA] CTD PMID:21914718 deoxycholic acid affects expression ISO RGD:10368 6480464 Deoxycholic Acid affects the expression of ABCC2 mRNA CTD PMID:21914718 desloratadine multiple interactions EXP 6480464 desloratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril] CTD PMID:22095822 dexamethasone multiple interactions ISO RGD:2366 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ABCC2 mRNA] CTD PMID:20032058 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of ABCC2 mRNA CTD PMID:20888898 dexamethasone increases expression ISO RGD:2366 6480464 Dexamethasone results in increased expression of ABCC2 mRNA, Dexamethasone results in increased expression of ABCC2 protein CTD PMID:12429353 more ... dexamethasone decreases expression ISO RGD:2366 6480464 Dexamethasone results in decreased expression of ABCC2 mRNA CTD PMID:15102944 , PMID:19922765 dextran sulfate decreases expression ISO RGD:10368 6480464 Dextran Sulfate results in decreased expression of ABCC2 mRNA, Dextran Sulfate results in decreased expression of ABCC2 protein CTD PMID:27580383 dextran sulfate affects response to substance ISO RGD:10368 6480464 ABCC2 protein affects the susceptibility to Dextran Sulfate CTD PMID:30701287 dextran sulfate multiple interactions ISO RGD:10368 6480464 ABCC2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine] CTD PMID:30701287 Diallyl sulfide increases expression ISO RGD:2366 6480464 allyl sulfide results in increased expression of ABCC2 protein CTD PMID:12920174 diarsenic trioxide decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:21783896 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of ABCC2 mRNA, Arsenic Trioxide results in decreased expression of ABCC2 protein CTD PMID:21945491 , PMID:22214486 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of ABCC2 mRNA, Arsenic Trioxide results in increased expression of ABCC2 protein CTD PMID:21945491 , PMID:27736728 diclofenac decreases activity EXP 6480464 Diclofenac results in decreased activity of ABCC2 protein CTD PMID:22646477 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of ABCC2 mRNA CTD PMID:19022234 diclofenac multiple interactions ISO RGD:2366 6480464 ABCC2 protein results in increased transport of and results in increased metabolism of and results in increased susceptibility to Diclofenac CTD PMID:25450747 dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of ABCC2 mRNA CTD PMID:28302478 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of ABCC2 mRNA CTD PMID:24464585 diethyl maleate increases expression ISO RGD:10368 6480464 diethyl maleate results in increased expression of ABCC2 mRNA CTD PMID:25270620 dimethylarsinic acid increases expression ISO RGD:2366 6480464 Cacodylic Acid results in increased expression of ABCC2 mRNA, Cacodylic Acid results in increased expression of ABCC2 protein CTD PMID:16436460 dioscin multiple interactions ISO RGD:2366 6480464 dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA], dioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein] CTD PMID:27317372 diosgenin multiple interactions ISO RGD:2366 6480464 [Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of ABCC2 mRNA CTD PMID:16105132 diosgenin increases expression ISO RGD:2366 6480464 Diosgenin results in increased expression of ABCC2 mRNA CTD PMID:16105132 dioxygen multiple interactions EXP 6480464 CA9 mutant form inhibits the reaction [[Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of ABCC2 mRNA] CTD PMID:26305601 dioxygen increases expression EXP 6480464 [Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of ABCC2 mRNA CTD PMID:26305601 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO RGD:2366 6480464 Antimony Potassium Tartrate results in increased expression of ABCC2 mRNA, Antimony Potassium Tartrate results in increased expression of ABCC2 protein CTD PMID:11408547 doramapimod increases expression ISO RGD:10368 6480464 BIRB 796 results in increased expression of ABCC2 mRNA CTD PMID:21328587 dorsomorphin multiple interactions ISO RGD:2366 6480464 dorsomorphin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA] more ... CTD PMID:27090119 , PMID:27702592 dorsomorphin multiple interactions ISO RGD:2366 15090804 dosomorphin inhibits the reaction [17alpha-ethynylestradiol decreases expression of Abcc2 mRNA in primary hepatocytes and liver lysate] RGD dothiepin increases expression EXP 6480464 Dothiepin results in increased expression of ABCC2 protein CTD PMID:12524417 doxorubicin decreases response to substance ISO RGD:2366 6480464 ABCC2 protein results in decreased susceptibility to Doxorubicin CTD PMID:11455017 doxorubicin affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of Doxorubicin CTD PMID:16611851 DPDPE affects export ISO RGD:2366 6480464 ABCC2 protein affects the export of Enkephalin more ... CTD PMID:15528320 E3040 multiple interactions EXP 6480464 [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of E 3040 analog CTD PMID:19628752 elemental selenium multiple interactions ISO RGD:2366 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 emodin increases expression ISO RGD:2366 6480464 Emodin results in increased expression of ABCC2 mRNA CTD PMID:19549930 emodin decreases expression ISO RGD:10368 6480464 Emodin results in decreased expression of ABCC2 mRNA CTD PMID:30517764 emodin decreases expression ISO RGD:2366 6480464 Emodin results in decreased expression of ABCC2 mRNA, Emodin results in decreased expression of ABCC2 protein CTD PMID:28161596 endosulfan decreases activity EXP 6480464 Endosulfan results in decreased activity of ABCC2 protein CTD PMID:24464585 endosulfan increases expression ISO RGD:2366 6480464 Endosulfan results in increased expression of ABCC2 mRNA CTD PMID:29391264 enilconazole decreases expression ISO RGD:10368 6480464 enilconazole results in decreased expression of ABCC2 mRNA CTD PMID:29451352 epoxiconazole increases expression ISO RGD:2366 6480464 epoxiconazole results in increased expression of ABCC2 mRNA CTD PMID:29038839 epoxiconazole multiple interactions ISO RGD:2366 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA CTD PMID:29038839 estrone 3-sulfate affects export EXP 6480464 ABCC2 protein affects the export of estrone sulfate CTD PMID:15652233 , PMID:16046661 estrone 3-sulfate increases activity ISO RGD:2366 6480464 estrone sulfate results in increased activity of ABCC2 protein, estrone sulfate results in increased activity of ABCC2 protein modified form CTD PMID:15904671 etacrynic acid increases transport EXP 6480464 ABCC2 protein results in increased transport of Ethacrynic Acid CTD PMID:16316932 ethoxyquin increases expression ISO RGD:10368 6480464 Ethoxyquin results in increased expression of ABCC2 mRNA CTD PMID:15833929 ethoxyquin multiple interactions ISO RGD:10368 6480464 [Ethoxyquin results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA CTD PMID:15833929 etoposide affects transport EXP 6480464 ABCC2 protein affects the transport of Etoposide CTD PMID:15751272 , PMID:15849751 etoposide multiple interactions EXP 6480464 Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide] CTD PMID:15849751 fenofibrate increases expression ISO RGD:2366 6480464 Fenofibrate results in increased expression of ABCC2 mRNA CTD PMID:27765674 Fexofenadine hydrochloride increases export ISO RGD:10368 6480464 ABCC2 protein results in increased export of fexofenadine CTD PMID:18245269 Fexofenadine hydrochloride multiple interactions EXP 6480464 [SLCO1B1 protein co-treated with ABCC2 protein] results in increased uptake of fexofenadine, [SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of fexofenadine CTD PMID:18180276 fipronil increases expression ISO RGD:10368 6480464 fipronil results in increased expression of ABCC2 mRNA CTD PMID:23962444 fipronil increases expression ISO RGD:2366 6480464 fipronil results in increased expression of ABCC2 mRNA CTD PMID:23962444 Fluo-3 multiple interactions ISO RGD:2366 6480464 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3], Cyclosporine inhibits the reaction [ABCC2 protein results in increased secretion of Fluo-3] CTD PMID:9794919 Fluo-3 increases secretion ISO RGD:2366 6480464 ABCC2 protein results in increased secretion of Fluo-3 CTD PMID:9794919 flutamide increases expression ISO RGD:2366 6480464 Flutamide results in increased expression of ABCC2 mRNA CTD PMID:24136188 fluvastatin affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of fluvastatin CTD PMID:16026004 fluvastatin multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of fluvastatin analog more ... CTD PMID:23562342 fluvastatin multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of fluvastatin analog more ... CTD PMID:23562342 , PMID:24909372 formononetin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA], formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA] CTD PMID:23867903 formononetin multiple interactions ISO RGD:2366 6480464 formononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA] CTD PMID:28414026 formononetin decreases expression EXP 6480464 formononetin results in decreased expression of ABCC2 mRNA CTD PMID:23867903 fosinopril decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Fosinopril CTD PMID:22095822 fosinopril multiple interactions ISO RGD:10368 6480464 ABCC2 protein affects the reaction [Fosinopril affects the export of Methotrexate] CTD PMID:22095822 fosinopril multiple interactions EXP 6480464 desloratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril] more ... CTD PMID:22095822 fosinopril increases export EXP 6480464 ABCC2 protein results in increased export of Fosinopril CTD PMID:22095822 fructose decreases expression ISO RGD:2366 6480464 Fructose results in decreased expression of ABCC2 mRNA, Fructose results in decreased expression of ABCC2 protein CTD PMID:31005848 fructose multiple interactions ISO RGD:2366 6480464 Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA] more ... CTD PMID:31005848 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCC2 protein], fulvestrant inhibits the reaction [Genistein results in increased expression of ABCC2 protein] CTD PMID:24685904 fulvestrant multiple interactions ISO RGD:2366 6480464 EGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]], fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein] CTD PMID:25813982 fulvestrant increases expression EXP 6480464 fulvestrant results in increased expression of ABCC2 protein CTD PMID:24685904 furan increases expression ISO RGD:2366 6480464 furan results in increased expression of ABCC2 mRNA CTD PMID:25539665 furosemide multiple interactions EXP 6480464 Furosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12704183 furosemide multiple interactions ISO RGD:2366 6480464 [Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-2, 4-dinitrophenylglutathione] CTD PMID:19782883 fusidic acid multiple interactions ISO RGD:2366 6480464 Fusidic Acid results in decreased expression of and results in decreased activity of ABCC2 protein CTD PMID:12106615 geneticin increases transport EXP 6480464 ABCC2 protein results in increased transport of antibiotic G 418 CTD PMID:20018165 genistein multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [Genistein results in increased expression of ABCC2 protein] more ... CTD PMID:15955639 more ... genistein increases expression EXP 6480464 Genistein results in increased expression of ABCC2 mRNA, Genistein results in increased expression of ABCC2 protein CTD PMID:21689630 , PMID:26394120 gentamycin increases expression ISO RGD:2366 6480464 Gentamicins results in increased expression of ABCC2 mRNA CTD PMID:22061828 geraniol multiple interactions ISO RGD:2366 6480464 geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA], geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] CTD PMID:31005848 Ginkgolide A increases expression EXP 6480464 ginkgolide A results in increased expression of ABCC2 mRNA CTD PMID:19034627 ginkgolide B increases expression EXP 6480464 ginkgolide B results in increased expression of ABCC2 mRNA CTD PMID:19034627 ginsenoside Rb2 increases expression ISO RGD:2366 6480464 ginsenoside Rb2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 ginsenoside Re increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 ginsenoside Re increases transport EXP 6480464 ABCC2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 ginsenoside Rg1 increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 ginsenoside Rg1 multiple interactions ISO RGD:2366 6480464 ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA], ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein] CTD PMID:32198087 ginsenoside Rg1 increases expression ISO RGD:10368 6480464 ginsenoside Rg1 results in increased expression of ABCC2 protein CTD PMID:29964319 ginsenoside Rg1 multiple interactions ISO RGD:10368 6480464 ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein], Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]] CTD PMID:29964319 ginsenoside Rg1 increases transport EXP 6480464 ABCC2 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 ginsenoside Rg2 increases expression ISO RGD:2366 6480464 ginsenoside Rg2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 glafenine decreases expression ISO RGD:2366 6480464 Glafenine results in decreased expression of ABCC2 mRNA CTD PMID:24136188 glucose multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-2 more ... CTD PMID:19782883 glutathione multiple interactions EXP 6480464 ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione], Glutathione promotes the reaction [ABCC2 protein affects the export of phenethyl isothiocyanate] CTD PMID:16002050 , PMID:16049127 glutathione affects abundance ISO RGD:2366 6480464 ABCC2 protein affects the abundance of Glutathione CTD PMID:25450747 glutathione affects transport EXP 6480464 ABCC2 protein affects the transport of Glutathione analog CTD PMID:20584751 glutathione affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of Glutathione CTD PMID:16611851 glutathione disulfide increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of Glutathione Disulfide CTD PMID:15276087 glutathione disulfide multiple interactions ISO RGD:2366 6480464 Acetaminophen promotes the reaction [ABCC2 protein results in increased transport of Glutathione Disulfide] CTD PMID:15276087 glyburide increases expression ISO RGD:2366 6480464 Glyburide results in increased expression of ABCC2 mRNA CTD PMID:27765674 glycyrrhetinate multiple interactions ISO RGD:2366 6480464 Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:18436619 glycyrrhetinic acid multiple interactions ISO RGD:2366 6480464 Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:18436619 Goe 6976 multiple interactions ISO RGD:2366 6480464 Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein] CTD PMID:18972403 more ... Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein] CTD PMID:29052767 guggulsterone multiple interactions ISO RGD:10368 6480464 pregna-4 more ... CTD PMID:25655198 GW 4064 increases expression ISO RGD:2366 6480464 GW 4064 results in increased expression of ABCC2 mRNA CTD PMID:14623915 , PMID:15644430 GW 4064 increases expression ISO RGD:2366 15090804 GW 4064 increases expression of Abcc2 mRNA in primary hepatocytes RGD GW 4064 multiple interactions ISO RGD:2366 15090804 GW 4064 inhibits the reaction [17alpha-ethynylestradiol decreases expression of Abcc2 mRNA in primary hepatocytes] RGD GW 4064 multiple interactions ISO RGD:2366 6480464 GW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein] CTD PMID:27090119 hepoxilin A3 increases export ISO RGD:10368 6480464 ABCC2 protein results in increased export of 8-hydroxy-11 more ... CTD PMID:30102254 heptachlor increases expression EXP 6480464 Heptachlor results in increased expression of ABCC2 mRNA CTD PMID:24464585 heptachlor decreases activity EXP 6480464 Heptachlor results in decreased activity of ABCC2 protein CTD PMID:24464585 Heptachlor epoxide increases expression ISO RGD:10368 6480464 Heptachlor Epoxide results in increased expression of ABCC2 mRNA CTD PMID:25270620 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of ABCC2 mRNA CTD PMID:20044591 hydrogen peroxide multiple interactions ISO RGD:10368 6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form] inhibits the reaction [Hydrogen Peroxide results in increased expression of ABCC2] CTD PMID:22914987 hydrogen peroxide increases expression ISO RGD:10368 6480464 Hydrogen Peroxide results in increased expression of ABCC2 CTD PMID:22914987 Hypaconitine multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of hypaconitine CTD PMID:23200901 imipenem hydrate multiple interactions ISO RGD:10368 6480464 [Vancomycin co-treated with Imipenem] affects the expression of ABCC2 mRNA CTD PMID:24657338 indole-3-methanol increases expression ISO RGD:2366 6480464 indole-3-carbinol results in increased expression of ABCC2 mRNA CTD PMID:11752103 indometacin multiple interactions EXP 6480464 Indomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein] more ... CTD PMID:12702717 more ... indometacin decreases activity EXP 6480464 Indomethacin results in decreased activity of ABCC2 protein CTD PMID:22646477 indometacin decreases expression ISO RGD:2366 6480464 Indomethacin results in decreased expression of ABCC2 mRNA, Indomethacin results in decreased expression of ABCC2 protein CTD PMID:17329856 indometacin decreases activity ISO RGD:2366 6480464 Indomethacin results in decreased activity of ABCC2 protein CTD PMID:16026004 irinotecan decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Irinotecan CTD PMID:16815871 irinotecan decreases response to substance ISO RGD:10368 6480464 ABCC2 gene mutant form results in decreased susceptibility to Irinotecan CTD PMID:32387182 irinotecan affects response to substance EXP 6480464 ABCC2 gene polymorphism affects the susceptibility to Irinotecan, ABCC2 gene polymorphism affects the susceptibility to Irinotecan metabolite CTD PMID:18981587 iron(III) nitrilotriacetate increases expression ISO RGD:10368 6480464 ferric nitrilotriacetate results in increased expression of ABCC2 mRNA CTD PMID:18617210 isoniazide multiple interactions ISO RGD:2366 6480464 [Lipopolysaccharides co-treated with Isoniazid] results in decreased expression of ABCC2 mRNA CTD PMID:25331106 isoniazide decreases expression ISO RGD:2366 6480464 Isoniazid results in decreased expression of ABCC2 mRNA CTD PMID:32673658 ivermectin increases expression ISO RGD:10368 6480464 Ivermectin results in increased expression of ABCC2 mRNA CTD PMID:24998875 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of ABCC2 protein CTD PMID:19070657 ketoconazole multiple interactions ISO RGD:2366 6480464 Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCC2 mRNA] CTD PMID:19766108 kojic acid multiple interactions ISO RGD:2366 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA, [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA CTD PMID:18544905 KT 5720 multiple interactions EXP 6480464 KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein] more ... CTD PMID:26049102 , PMID:29052767 KT 5720 multiple interactions ISO RGD:2366 6480464 KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein], KT 5720 inhibits the reaction [Taurolithocholic Acid results in decreased activity of and affects the localization of ABCC2 protein] CTD PMID:29052767 , PMID:31300867 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [3' more ... CTD PMID:19326901 , PMID:22914566 L-ascorbic acid multiple interactions ISO RGD:2366 6480464 Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA], Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] CTD PMID:31005848 L-cysteine multiple interactions EXP 6480464 ABCC2 protein affects the transport of [Mercury co-treated with Cysteine] CTD PMID:21134393 L-cysteine multiple interactions ISO RGD:2366 6480464 ABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]] more ... CTD PMID:18511429 L-methionine multiple interactions ISO RGD:10368 6480464 [LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA, [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA CTD PMID:24384915 L-methionine multiple interactions ISO RGD:2366 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA, [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 protein CTD PMID:17640958 , PMID:24384915 leukotriene C4 increases transport ISO RGD:2366 6480464 ABCC2 protein modified form results in increased transport of Leukotriene C4 CTD PMID:15904671 leukotriene C4 multiple interactions EXP 6480464 verlukast inhibits the reaction [ABCC2 protein results in increased transport of Leukotriene C4] CTD PMID:27676153 leukotriene C4 affects transport EXP 6480464 ABCC2 protein affects the transport of Leukotriene C4 CTD PMID:11500505 more ... leukotriene C4 affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Leukotriene C4 CTD PMID:15507541 more ... levetiracetam increases expression ISO RGD:2366 6480464 Levetiracetam results in increased expression of ABCC2 protein CTD PMID:18473823 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of ABCC2 protein CTD PMID:15205115 lipopolysaccharide affects localization ISO RGD:2366 6480464 Lipopolysaccharides affects the localization of ABCC2 protein CTD PMID:28842383 lipopolysaccharide decreases expression ISO RGD:2366 6480464 Lipopolysaccharides results in decreased expression of ABCC2 mRNA CTD PMID:15205115 more ... lipopolysaccharide decreases expression ISO RGD:10368 6480464 Lipopolysaccharides results in decreased expression of ABCC2 mRNA CTD PMID:14709616 more ... lipopolysaccharide multiple interactions ISO RGD:2366 6480464 [Lipopolysaccharides co-treated with Isoniazid] results in decreased expression of ABCC2 mRNA more ... CTD PMID:12706339 more ... lipopolysaccharide decreases activity ISO RGD:10368 6480464 Lipopolysaccharides results in decreased activity of ABCC2 protein CTD PMID:14709616 lithocholic acid multiple interactions ISO RGD:2366 6480464 [Lithocholic Acid binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA CTD PMID:21311750 lithocholic acid increases expression ISO RGD:10368 6480464 Lithocholic Acid results in increased expression of ABCC2 mRNA, Lithocholic Acid results in increased expression of ABCC2 protein CTD PMID:20977460 , PMID:25582706 lithocholic acid multiple interactions EXP 6480464 [Cyclosporine results in decreased activity of ABCC2 protein] which results in increased abundance of Lithocholic Acid, [Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA CTD PMID:14570758 , PMID:26198044 lithocholic acid affects localization ISO RGD:10368 6480464 Lithocholic Acid affects the localization of ABCC2 protein CTD PMID:16436656 lithocholic acid multiple interactions ISO RGD:10368 6480464 [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein more ... CTD PMID:18032408 , PMID:20977460 lithocholic acid increases expression ISO RGD:2366 6480464 Lithocholic Acid results in increased expression of ABCC2 mRNA CTD PMID:20888898 lithocholic acid increases expression EXP 6480464 Lithocholic Acid results in increased expression of ABCC2 mRNA CTD PMID:20888898 lopinavir increases abundance EXP 6480464 ABCC2 protein alternative form results in increased abundance of Lopinavir CTD PMID:22027652 lopinavir increases secretion EXP 6480464 ABCC2 protein results in increased secretion of Lopinavir CTD PMID:22027652 Loratadine multiple interactions EXP 6480464 Loratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril] CTD PMID:22095822 lovastatin multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of Lovastatin analog more ... CTD PMID:15616150 , PMID:23562342 lovastatin increases expression ISO RGD:2366 6480464 Lovastatin results in increased expression of ABCC2 mRNA CTD PMID:26739623 lovastatin decreases activity ISO RGD:2366 6480464 Lovastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 lovastatin multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of Lovastatin analog more ... CTD PMID:15616150 more ... lovastatin decreases activity EXP 6480464 Lovastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 luteolin multiple interactions ISO RGD:10368 6480464 [Luteolin co-treated with Cisplatin] results in increased expression of ABCC2 protein, Luteolin inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein] CTD PMID:23770416 LY294002 multiple interactions EXP 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mRNA] CTD PMID:15896333 macitentan decreases expression EXP 6480464 macitentan results in decreased expression of ABCC2 mRNA CTD PMID:28369585 manganese(II) chloride decreases methylation ISO RGD:2366 6480464 manganese chloride results in decreased methylation of ABCC2 gene CTD PMID:28801915 manganese(II) chloride increases expression ISO RGD:2366 6480464 manganese chloride results in increased expression of ABCC2 mRNA CTD PMID:28801915 Maprotiline decreases expression ISO RGD:2366 6480464 Maprotiline results in decreased expression of ABCC2 mRNA CTD PMID:27765674 Meclizine multiple interactions ISO RGD:10368 6480464 [Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of ABCC2 mRNA CTD PMID:15272053 mercury atom affects response to substance ISO RGD:10368 6480464 ABCC2 gene mutant form affects the susceptibility to Mercury CTD PMID:25145654 mercury atom affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Mercury CTD PMID:23059061 mercury atom increases transport EXP 6480464 ABCC2 protein results in increased transport of Mercury CTD PMID:24039982 mercury atom multiple interactions EXP 6480464 ABCC2 gene SNP affects the susceptibility to and affects the abundance of Mercury more ... CTD PMID:21134393 more ... mercury atom increases export ISO RGD:10368 6480464 ABCC2 protein results in increased export of Mercury CTD PMID:25145654 mercury atom affects response to substance ISO RGD:2366 6480464 ABCC2 gene mutant form affects the susceptibility to Mercury CTD PMID:25145654 mercury atom increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of Mercury CTD PMID:25145654 mercury dichloride affects response to substance ISO RGD:2366 6480464 ABCC2 gene mutant form affects the susceptibility to Mercuric Chloride CTD PMID:25145654 mercury dichloride increases expression ISO RGD:2366 6480464 Mercuric Chloride results in increased expression of ABCC2 mRNA CTD PMID:32599119 mercury dichloride increases expression ISO RGD:10368 6480464 Mercuric Chloride results in increased expression of ABCC2 mRNA CTD PMID:27720909 mercury dichloride multiple interactions ISO RGD:10368 6480464 ABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA] CTD PMID:24039982 mercury dichloride affects expression ISO RGD:2366 6480464 Mercuric Chloride affects the expression of ABCC2 mRNA CTD PMID:28536007 mercury dichloride multiple interactions ISO RGD:2366 6480464 ABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]] more ... CTD PMID:18511429 mercury dichloride decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Mercuric Chloride CTD PMID:21783896 mercury dichloride affects response to substance ISO RGD:10368 6480464 ABCC2 gene mutant form affects the susceptibility to Mercuric Chloride CTD PMID:25145654 mercury(0) increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of Mercury CTD PMID:25145654 mercury(0) increases transport EXP 6480464 ABCC2 protein results in increased transport of Mercury CTD PMID:24039982 mercury(0) affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Mercury CTD PMID:23059061 mercury(0) multiple interactions EXP 6480464 ABCC2 gene SNP affects the susceptibility to and affects the abundance of Mercury more ... CTD PMID:21134393 more ... mercury(0) increases export ISO RGD:10368 6480464 ABCC2 protein results in increased export of Mercury CTD PMID:25145654 mercury(0) affects response to substance ISO RGD:10368 6480464 ABCC2 gene mutant form affects the susceptibility to Mercury CTD PMID:25145654 mercury(0) affects response to substance ISO RGD:2366 6480464 ABCC2 gene mutant form affects the susceptibility to Mercury CTD PMID:25145654 Mesaconitine multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of mesaconitine CTD PMID:23200901 metformin increases expression EXP 6480464 Metformin results in increased expression of ABCC2 mRNA CTD PMID:19022234 methapyrilene increases expression ISO RGD:2366 6480464 Methapyrilene results in increased expression of ABCC2 mRNA CTD PMID:22484513 , PMID:28529062 methotrexate multiple interactions EXP 6480464 ABCC2 gene polymorphism affects the susceptibility to and affects the metabolism of Methotrexate more ... CTD PMID:15864128 more ... methotrexate affects response to substance EXP 6480464 ABCC2 gene SNP affects the susceptibility to Methotrexate CTD PMID:18381794 , PMID:23222202 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of ABCC2 mRNA CTD PMID:23897011 methotrexate multiple interactions ISO RGD:10368 6480464 ABCC2 protein affects the reaction [Fosinopril affects the export of Methotrexate] CTD PMID:22095822 methotrexate decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Methotrexate CTD PMID:19394316 , PMID:22095822 methotrexate affects export ISO RGD:10368 6480464 ABCC2 protein affects the export of Methotrexate CTD PMID:22095822 methotrexate affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of Methotrexate CTD PMID:16611851 methotrexate increases import ISO RGD:2366 6480464 ABCC2 protein results in increased import of Methotrexate CTD PMID:19067394 methotrexate decreases expression ISO RGD:2366 6480464 Methotrexate results in decreased expression of ABCC2 mRNA, Methotrexate results in decreased expression of ABCC2 protein CTD PMID:16925582 methotrexate increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of Methotrexate CTD PMID:12608533 methotrexate multiple interactions ISO RGD:2366 6480464 Leucovorin inhibits the reaction [Methotrexate results in decreased expression of ABCC2 protein] CTD PMID:16925582 methotrexate affects transport EXP 6480464 ABCC2 protein affects the transport of Methotrexate CTD PMID:11500505 methotrexate increases response to substance EXP 6480464 ABCC2 polymorphism results in increased susceptibility to Methotrexate, ABCC2 protein mutant form results in increased susceptibility to Methotrexate CTD PMID:15864128 , PMID:21887680 methoxsalen multiple interactions EXP 6480464 [Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin more ... CTD PMID:29079042 methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of ABCC2 protein CTD PMID:29079042 methoxsalen decreases expression EXP 6480464 Methoxsalen results in decreased expression of ABCC2 mRNA CTD PMID:29079042 methylarsonic acid increases expression ISO RGD:2366 6480464 monomethylarsonic acid results in increased expression of ABCC2 mRNA, monomethylarsonic acid results in increased expression of ABCC2 protein CTD PMID:16436460 methylarsonic acid increases expression EXP 6480464 monomethylarsonic acid results in increased expression of ABCC2 mRNA CTD PMID:24091636 methylisothiazolinone increases expression EXP 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of ABCC2 mRNA CTD PMID:31629900 methylmercury chloride increases expression ISO RGD:10368 6480464 methylmercuric chloride results in increased expression of ABCC2 mRNA CTD PMID:27720909 methylmercury chloride increases expression ISO RGD:2366 6480464 methylmercuric chloride results in increased expression of ABCC2 mRNA CTD PMID:28536007 metronidazole decreases expression ISO RGD:10368 6480464 Metronidazole results in decreased expression of ABCC2 mRNA CTD PMID:24657338 microcystin LF multiple interactions EXP 6480464 microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:31348918 microcystin LF increases export EXP 6480464 ABCC2 protein results in increased export of microcystin-LF CTD PMID:31348918 microcystin RR multiple interactions EXP 6480464 microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:31348918 microcystin RR increases export EXP 6480464 ABCC2 protein results in increased export of microcystin RR CTD PMID:31348918 microcystin-LR increases expression ISO RGD:10368 6480464 cyanoginosin LR results in increased expression of ABCC2 mRNA CTD PMID:17654400 microcystin-LR increases export EXP 6480464 ABCC2 protein results in increased export of cyanoginosin LR CTD PMID:31348918 microcystin-LR multiple interactions EXP 6480464 cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 56-carboxy-2', 7'-dichlorofluorescein] CTD PMID:31348918 Midecamycin decreases activity EXP 6480464 midecamycin results in decreased activity of ABCC2 protein CTD PMID:15618715 Midecamycin decreases activity ISO RGD:2366 6480464 midecamycin results in decreased activity of ABCC2 protein CTD PMID:15618715 mifepristone increases expression ISO RGD:10368 6480464 Mifepristone results in increased expression of ABCC2 mRNA CTD PMID:15456840 MK 571 multiple interactions ISO RGD:2366 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite, ABCC2 protein affects the reaction [verlukast results in decreased secretion of Chenodeoxycholic Acid] CTD PMID:20089784 , PMID:21262925 MK 571 multiple interactions EXP 6480464 [verlukast results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan more ... CTD PMID:19647055 more ... MK 571 decreases activity ISO RGD:2366 6480464 verlukast results in decreased activity of ABCC2 protein, verlukast results in decreased activity of ABCC2 protein modified form CTD PMID:15904671 MK 571 decreases activity EXP 6480464 verlukast results in decreased activity of ABCC2 protein CTD PMID:15451006 more ... mono(2-ethylhexyl) phthalate affects expression ISO RGD:10368 6480464 mono-2-ethylhexylphthalate affects the expression of ABCC2 mRNA CTD PMID:22401849 mono(glucosyluronic acid)bilirubin increases expression ISO RGD:2366 6480464 bilirubin glucuronate results in increased expression of ABCC2 mRNA CTD PMID:11897625 mono(glucosyluronic acid)bilirubin affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of bilirubin glucuronate CTD PMID:16611851 monosodium L-glutamate multiple interactions ISO RGD:10368 6480464 [Sodium Glutamate co-treated with Bezafibrate] results in increased expression of ABCC2 mRNA CTD PMID:21549692 montelukast multiple interactions EXP 6480464 montelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM] more ... CTD PMID:19952419 myricetin multiple interactions EXP 6480464 myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine] more ... CTD PMID:15896345 myricetin decreases activity EXP 6480464 myricetin results in decreased activity of ABCC2 protein CTD PMID:15670588 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-2-4-bromocinnamylaminoethyl-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein] CTD PMID:26049102 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:2366 6480464 N-2-4-bromocinnamylaminoethyl-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]] more ... CTD PMID:27743861 , PMID:31300867 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [3' more ... CTD PMID:22914566 , PMID:23867903 N-Acetyl-S-(1,2-dichlorovinyl)-cysteine increases transport ISO RGD:10368 6480464 ABCC2 protein results in increased transport of S-1, 2-dichlorovinyl-N-acetylcysteine CTD PMID:20060011 N-Acetyl-S-(1,2-dichlorovinyl)-cysteine multiple interactions ISO RGD:10368 6480464 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1, 2-dichlorovinyl-N-acetylcysteine] CTD PMID:20060011 N-hydroxy-PhIP multiple interactions ISO RGD:10368 6480464 [ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo4 more ... CTD PMID:30701287 N-nitrosodiethylamine multiple interactions ISO RGD:2366 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA more ... CTD PMID:18544905 , PMID:23665939 N-Vinyl-2-pyrrolidone multiple interactions ISO RGD:2366 6480464 [N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which results in increased expression of ABCC2 mRNA CTD PMID:22037397 nelfinavir affects transport EXP 6480464 ABCC2 protein affects the transport of Nelfinavir CTD PMID:16041239 neomycin multiple interactions ISO RGD:10368 6480464 [Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA CTD PMID:24657338 nifedipine increases expression ISO RGD:2366 6480464 Nifedipine results in increased expression of ABCC2 mRNA CTD PMID:12206135 nimesulide increases expression ISO RGD:2366 6480464 nimesulide results in increased expression of ABCC2 mRNA CTD PMID:24136188 nitric oxide multiple interactions ISO RGD:2366 6480464 ABCC2 affects the reaction [Ursodeoxycholic Acid results in increased secretion of Nitric Oxide] CTD PMID:20683964 nitric oxide multiple interactions EXP 6480464 ABCC2 gene SNP affects the susceptibility to [Air Pollutants results in increased abundance of Nitric Oxide] CTD PMID:29681089 nitrogen dioxide multiple interactions EXP 6480464 ABCC2 gene SNP affects the susceptibility to [Air Pollutants results in increased abundance of Nitrogen Dioxide] CTD PMID:29681089 nocodazole decreases expression EXP 6480464 Nocodazole results in decreased expression of ABCC2 mRNA, Nocodazole results in decreased expression of ABCC2 protein CTD PMID:10691972 norgestimate decreases activity EXP 6480464 norgestimate results in decreased activity of ABCC2 protein CTD PMID:16049127 notoginsenoside R1 increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 notoginsenoside R1 increases transport EXP 6480464 ABCC2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 obeticholic acid multiple interactions ISO RGD:2366 6480464 obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA] CTD PMID:27255380 obeticholic acid multiple interactions ISO RGD:10368 6480464 NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]] more ... CTD PMID:29660435 obeticholic acid increases expression ISO RGD:2366 6480464 obeticholic acid results in increased expression of ABCC2 mRNA CTD PMID:15644430 ochratoxin A multiple interactions EXP 6480464 biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] more ... CTD PMID:15955639 ochratoxin A increases expression ISO RGD:2366 6480464 ochratoxin A results in increased expression of ABCC2 mRNA CTD PMID:29126803 ochratoxin A affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of ochratoxin A CTD PMID:28532671 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of ABCC2 mRNA CTD PMID:26505656 ochratoxin A decreases expression ISO RGD:2366 6480464 ochratoxin A results in decreased expression of ABCC2 mRNA CTD PMID:16251485 , PMID:23358140 ochratoxin A affects transport EXP 6480464 ABCC2 protein affects the transport of ochratoxin A CTD PMID:19505989 , PMID:28532671 ochratoxin A affects export EXP 6480464 ABCC2 protein affects the export of ochratoxin A CTD PMID:15955639 olmesartan affects transport EXP 6480464 ABCC2 protein affects the transport of olmesartan CTD PMID:19505989 oltipraz multiple interactions ISO RGD:10368 6480464 [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein, [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA CTD PMID:15833929 , PMID:18032408 oltipraz increases expression ISO RGD:2366 6480464 oltipraz results in increased expression of ABCC2 mRNA, oltipraz results in increased expression of ABCC2 protein CTD PMID:12920174 oltipraz increases expression EXP 6480464 oltipraz results in increased expression of ABCC2 mRNA, oltipraz results in increased expression of ABCC2 protein CTD PMID:16837569 , PMID:25752797 oltipraz increases expression ISO RGD:10368 6480464 oltipraz results in increased expression of ABCC2 mRNA CTD PMID:15833929 organoselenium compound multiple interactions EXP 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA CTD PMID:25167922 orphenadrine multiple interactions ISO RGD:2366 6480464 [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA CTD PMID:23665939 ortho-Aminoazotoluene increases expression ISO RGD:10368 6480464 o-Aminoazotoluene results in increased expression of ABCC2 mRNA CTD PMID:21672546 ortho-Aminoazotoluene multiple interactions ISO RGD:10368 6480464 NR1I3 gene mutant form inhibits the reaction [o-Aminoazotoluene results in increased expression of ABCC2 mRNA] CTD PMID:21672546 p-menthan-3-ol increases expression ISO RGD:10368 6480464 Menthol results in increased expression of ABCC2 mRNA CTD PMID:24594507 paclitaxel decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Paclitaxel CTD PMID:15849751 paclitaxel increases expression ISO RGD:10368 6480464 Paclitaxel results in increased expression of ABCC2 mRNA, Paclitaxel results in increased expression of ABCC2 protein CTD PMID:28242239 paclitaxel affects expression EXP 6480464 Paclitaxel affects the expression of ABCC2 mRNA CTD PMID:20737486 paclitaxel increases export EXP 6480464 ABCC2 protein results in increased export of Paclitaxel CTD PMID:19952419 paclitaxel affects transport EXP 6480464 ABCC2 protein affects the transport of Paclitaxel CTD PMID:15849751 paclitaxel multiple interactions EXP 6480464 montelukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel] more ... CTD PMID:15849751 , PMID:19952419 paclitaxel affects response to substance EXP 6480464 ABCC2 protein affects the susceptibility to Paclitaxel CTD PMID:15645438 pantoprazole multiple interactions EXP 6480464 pantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12702717 paracetamol affects expression ISO RGD:10368 6480464 Acetaminophen affects the expression of ABCC2 mRNA CTD PMID:17562736 paracetamol multiple interactions EXP 6480464 [Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite CTD PMID:32472168 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ABCC2 mRNA CTD PMID:21420995 more ... paracetamol increases expression ISO RGD:2366 6480464 Acetaminophen results in increased expression of ABCC2 mRNA, Acetaminophen results in increased expression of ABCC2 protein CTD PMID:15276087 , PMID:17126469 paracetamol increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of Acetaminophen CTD PMID:16271353 paracetamol affects response to substance ISO RGD:2366 6480464 ABCC2 protein affects the susceptibility to Acetaminophen CTD PMID:16271353 paracetamol multiple interactions ISO RGD:2366 6480464 [Acetaminophen co-treated with Uranium analog] results in increased expression of ABCC2 mRNA more ... CTD PMID:15276087 more ... paracetamol affects export ISO RGD:2366 6480464 ABCC2 protein affects the export of Acetaminophen analog CTD PMID:15860656 paracetamol increases expression ISO RGD:10368 6480464 Acetaminophen results in increased expression of ABCC2 mRNA, Acetaminophen results in increased expression of ABCC2 protein CTD PMID:15496496 , PMID:16177239 paracetamol multiple interactions ISO RGD:10368 6480464 [Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC2 mRNA, [Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC2 mRNA CTD PMID:17934960 paroxetine increases expression EXP 6480464 Paroxetine results in increased expression of ABCC2 protein CTD PMID:12524417 PCB138 multiple interactions ISO RGD:10368 6480464 [2 more ... CTD PMID:25510870 pentachlorophenol increases expression ISO RGD:10368 6480464 Pentachlorophenol results in increased expression of ABCC2 mRNA CTD PMID:23892564 perfluorodecanoic acid increases expression ISO RGD:10368 6480464 perfluorodecanoic acid results in increased expression of ABCC2 mRNA CTD PMID:27344344 perfluorodecanoic acid multiple interactions ISO RGD:10368 6480464 PPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC2 mRNA] CTD PMID:27344344 perfluorononanoic acid increases expression ISO RGD:10368 6480464 perfluorononanoic acid results in increased expression of ABCC2 mRNA CTD PMID:29112762 perfluorooctane-1-sulfonic acid increases expression ISO RGD:2366 6480464 perfluorooctane sulfonic acid results in increased expression of ABCC2 mRNA CTD PMID:18692542 more ... perfluorooctanoic acid increases expression ISO RGD:10368 6480464 perfluorooctanoic acid results in increased expression of ABCC2 mRNA CTD PMID:17681415 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ABCC2 mRNA CTD PMID:32253466 perhexiline increases expression ISO RGD:2366 6480464 Perhexiline results in increased expression of ABCC2 mRNA CTD PMID:27765674 phalloidin decreases localization ISO RGD:2366 6480464 Phalloidine results in decreased localization of ABCC2 protein CTD PMID:12169763 phenethyl isothiocyanate affects export EXP 6480464 ABCC2 protein affects the export of phenethyl isothiocyanate CTD PMID:16002050 phenethyl isothiocyanate multiple interactions EXP 6480464 Glutathione promotes the reaction [ABCC2 protein affects the export of phenethyl isothiocyanate] CTD PMID:16002050 phenobarbital increases expression ISO RGD:10368 6480464 Phenobarbital results in increased expression of ABCC2 mRNA, Phenobarbital results in increased expression of ABCC2 protein CTD PMID:15986414 more ... phenobarbital affects expression ISO RGD:10368 6480464 Phenobarbital affects the expression of ABCC2 mRNA CTD PMID:23091169 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of ABCC2 mRNA CTD PMID:19159669 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of ABCC2 mRNA, Phenobarbital results in increased expression of ABCC2 protein CTD PMID:16837569 , PMID:19084549 phenobarbital increases expression ISO RGD:2366 6480464 Phenobarbital results in increased expression of ABCC2 mRNA, Phenobarbital results in increased expression of ABCC2 protein CTD PMID:11328961 more ... phenobarbital multiple interactions ISO RGD:2366 6480464 KN 62 inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein], Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein] CTD PMID:18473823 phenol red affects export ISO RGD:2366 6480464 ABCC2 protein affects the export of Phenolsulfonphthalein CTD PMID:15618741 phenytoin affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of Phenytoin CTD PMID:12663688 , PMID:14636316 phenytoin multiple interactions ISO RGD:2366 6480464 KN 62 inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein], Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] CTD PMID:18473823 phenytoin increases expression ISO RGD:2366 6480464 Phenytoin results in increased expression of ABCC2 protein CTD PMID:18473823 phenytoin affects response to substance EXP 6480464 ABCC2 protein affects the susceptibility to Phenytoin CTD PMID:17376120 PhIP multiple interactions EXP 6480464 [Cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:16356829 PhIP multiple interactions ISO RGD:10368 6480464 [ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo4 more ... CTD PMID:30701287 PhIP affects metabolic processing ISO RGD:10368 6480464 ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:30701287 PhIP affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:16611851 PhIP increases transport EXP 6480464 ABCC2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:11306678 PhIP increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:11306678 PhIP affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine CTD PMID:15057744 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine results in increased expression of ABCC2 mRNA CTD PMID:18680760 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:2366 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein] more ... CTD PMID:18473823 physcion decreases expression ISO RGD:2366 6480464 physcione results in decreased expression of ABCC2 mRNA, physcione results in decreased expression of ABCC2 protein CTD PMID:28161596 piperonyl butoxide increases expression ISO RGD:10368 6480464 Piperonyl Butoxide results in increased expression of ABCC2 mRNA CTD PMID:19690152 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCC2 mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO RGD:2366 6480464 pirinixic acid results in decreased expression of ABCC2 mRNA CTD PMID:19162173 , PMID:21318169 pitavastatin affects transport EXP 6480464 ABCC2 protein affects the transport of pitavastatin CTD PMID:15955871 pitavastatin multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of pitavastatin analog more ... CTD PMID:23562342 pitavastatin multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of pitavastatin analog more ... CTD PMID:23562342 pitavastatin(1-) affects transport EXP 6480464 ABCC2 protein affects the transport of pitavastatin CTD PMID:15955871 pitavastatin(1-) multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of pitavastatin analog more ... CTD PMID:23562342 pitavastatin(1-) multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of pitavastatin analog more ... CTD PMID:23562342 platinum decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Platinum CTD PMID:15688364 platinum(0) decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Platinum CTD PMID:15688364 pravastatin affects export EXP 6480464 ABCC2 protein affects the export of Pravastatin CTD PMID:15901800 pravastatin increases expression ISO RGD:2366 6480464 Pravastatin results in increased expression of ABCC2 protein CTD PMID:24909372 pravastatin multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of Pravastatin analog more ... CTD PMID:23562342 , PMID:24909372 pravastatin multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of Pravastatin analog more ... CTD PMID:23562342 pravastatin affects transport ISO RGD:10368 6480464 ABCC2 protein affects the transport of Pravastatin CTD PMID:15955871 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:10368 6480464 [Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of ABCC2 mRNA, Endotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA] CTD PMID:15456840 , PMID:22496397 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:10368 6480464 Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA CTD PMID:15456840 , PMID:22496397 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:2366 6480464 Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA, Pregnenolone Carbonitrile results in increased expression of ABCC2 protein CTD PMID:15917434 more ... probenecid multiple interactions ISO RGD:2366 6480464 [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite, [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium CTD PMID:19853032 , PMID:20089784 probenecid multiple interactions EXP 6480464 Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein] more ... CTD PMID:11477083 more ... probenecid increases activity ISO RGD:2366 6480464 Probenecid results in increased activity of ABCC2 protein CTD PMID:15904671 probenecid increases activity EXP 6480464 Probenecid results in increased activity of ABCC2 protein CTD PMID:15849751 , PMID:17478601 probenecid increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of Probenecid CTD PMID:12608533 prochloraz multiple interactions ISO RGD:2366 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA CTD PMID:29038839 prochloraz increases expression ISO RGD:2366 6480464 prochloraz results in increased expression of ABCC2 mRNA CTD PMID:29038839 progesterone decreases activity EXP 6480464 Progesterone results in decreased activity of ABCC2 protein CTD PMID:16049127 propane-1,2-diol multiple interactions ISO RGD:10368 6480464 [Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC2 mRNA CTD PMID:17934960 protein kinase inhibitor multiple interactions ISO RGD:2366 6480464 Protein Kinase Inhibitors inhibits the reaction [[EGF protein co-treated with 1-4-6-bromobenzo1 more ... CTD PMID:25813982 Prulifloxacin affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of prulifloxacin metabolite CTD PMID:15618759 psoralen decreases expression ISO RGD:2366 6480464 Ficusin results in decreased expression of ABCC2 mRNA, Ficusin results in decreased expression of ABCC2 protein CTD PMID:30597224 pyrazinecarboxamide multiple interactions ISO RGD:2366 6480464 obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA] CTD PMID:27255380 pyrazinecarboxamide decreases expression ISO RGD:2366 6480464 Pyrazinamide results in decreased expression of ABCC2 mRNA, Pyrazinamide results in decreased expression of ABCC2 protein CTD PMID:27255380 pyrrolidines decreases expression ISO RGD:2366 6480464 Pyrrolidines analog results in decreased expression of ABCC2 mRNA CTD PMID:26365562 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] CTD PMID:15955639 quercetin multiple interactions ISO RGD:2366 6480464 Quercetin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA] CTD PMID:11408547 reactive oxygen species increases expression ISO RGD:2366 6480464 Reactive Oxygen Species results in increased expression of ABCC2 CTD PMID:11264000 resveratrol multiple interactions ISO RGD:2366 6480464 [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite more ... CTD PMID:20089784 , PMID:25418378 resveratrol decreases expression ISO RGD:2366 6480464 resveratrol results in decreased expression of ABCC2 mRNA, resveratrol results in decreased expression of ABCC2 protein CTD PMID:26394120 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of ABCC2 mRNA, resveratrol results in decreased expression of ABCC2 protein CTD PMID:26394120 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] more ... CTD PMID:15955639 more ... resveratrol affects export EXP 6480464 ABCC2 protein affects the export of resveratrol CTD PMID:15686436 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of ABCC2 more ... CTD PMID:11836020 more ... rifampicin multiple interactions EXP 6480464 [Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein CTD PMID:16952291 rifampicin affects export EXP 6480464 ABCC2 protein affects the export of Rifampin CTD PMID:15652233 robinetin decreases activity EXP 6480464 robinetin results in decreased activity of ABCC2 protein CTD PMID:15670588 robinetin multiple interactions EXP 6480464 robinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon] CTD PMID:15670588 rosuvastatin calcium affects secretion ISO RGD:2366 6480464 ABCC2 protein affects the secretion of Rosuvastatin Calcium CTD PMID:19853032 rosuvastatin calcium multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog more ... CTD PMID:23562342 rosuvastatin calcium increases expression ISO RGD:2366 6480464 Rosuvastatin Calcium results in increased expression of ABCC2 protein CTD PMID:24909372 rosuvastatin calcium multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium more ... CTD PMID:19853032 more ... rubitecan increases expression EXP 6480464 rubitecan results in increased expression of ABCC2 mRNA CTD PMID:15342794 S-(2,4-dinitrophenyl)glutathione multiple interactions ISO RGD:2366 6480464 [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-2 more ... CTD PMID:15276087 more ... S-(2,4-dinitrophenyl)glutathione affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of S-2, 4-dinitrophenylglutathione CTD PMID:15652244 more ... S-(2,4-dinitrophenyl)glutathione increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of S-2, 4-dinitrophenylglutathione CTD PMID:15276087 , PMID:9067317 S-(2,4-dinitrophenyl)glutathione increases export ISO RGD:2366 6480464 ABCC2 protein results in increased export of S-2, 4-dinitrophenylglutathione CTD PMID:19067394 S-(2,4-dinitrophenyl)glutathione affects transport EXP 6480464 ABCC2 protein affects the transport of S-2, 4-dinitrophenylglutathione CTD PMID:15846474 , PMID:9525973 S-nitrosoglutathione affects transport ISO RGD:2366 6480464 ABCC2 affects the transport of S-Nitrosoglutathione CTD PMID:20683964 saquinavir affects export EXP 6480464 ABCC2 protein affects the export of Saquinavir CTD PMID:15832500 saquinavir multiple interactions EXP 6480464 montelukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir], verlukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir] CTD PMID:19952419 saquinavir increases export EXP 6480464 ABCC2 protein results in increased export of Saquinavir CTD PMID:18535159 , PMID:19952419 selenium atom multiple interactions ISO RGD:2366 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 senecionine decreases expression EXP 6480464 senecionine results in decreased expression of ABCC2 mRNA CTD PMID:26100227 senecionine decreases expression ISO RGD:10368 6480464 senecionine results in decreased expression of ABCC2 mRNA CTD PMID:31606820 sevoflurane affects expression ISO RGD:2366 6480464 sevoflurane affects the expression of ABCC2 mRNA CTD PMID:15967596 simvastatin multiple interactions ISO RGD:2366 6480464 ABCC2 protein binds to and results in increased uptake of Simvastatin analog more ... CTD PMID:15616150 , PMID:23562342 simvastatin decreases expression ISO RGD:2366 6480464 Simvastatin results in decreased expression of ABCC2 mRNA CTD PMID:27765674 simvastatin affects response to substance EXP 6480464 ABCC2 polymorphism affects the susceptibility to Simvastatin CTD PMID:22186618 simvastatin decreases activity ISO RGD:2366 6480464 Simvastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 simvastatin decreases activity EXP 6480464 Simvastatin analog results in decreased activity of ABCC2 protein CTD PMID:15616150 simvastatin multiple interactions EXP 6480464 ABCC2 protein binds to and results in increased uptake of Simvastatin analog more ... CTD PMID:15616150 , PMID:23562342 sincalide affects export EXP 6480464 ABCC2 protein affects the export of Sincalide CTD PMID:15665139 , PMID:16046661 sirolimus decreases expression ISO RGD:2366 6480464 Sirolimus results in decreased expression of ABCC2 mRNA CTD PMID:11589784 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of ABCC2 mRNA CTD PMID:12727804 sodium arsenate increases expression ISO RGD:2366 6480464 sodium arsenate results in increased expression of ABCC2 mRNA, sodium arsenate results in increased expression of ABCC2 protein CTD PMID:11408547 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ABCC2 mRNA, sodium arsenite results in increased expression of ABCC2 protein CTD PMID:11408547 more ... sodium arsenite decreases expression ISO RGD:10368 6480464 sodium arsenite results in decreased expression of ABCC2 mRNA CTD PMID:29108910 sodium arsenite increases expression ISO RGD:2366 6480464 sodium arsenite results in increased expression of ABCC2 mRNA, sodium arsenite results in increased expression of ABCC2 protein CTD PMID:11408547 more ... sodium arsenite increases expression ISO RGD:10368 6480464 sodium arsenite results in increased expression of ABCC2 mRNA CTD PMID:20008137 more ... sodium arsenite multiple interactions ISO RGD:2366 6480464 Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA], Quercetin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA] CTD PMID:11408547 sodium arsenite decreases response to substance ISO RGD:2366 6480464 ABCC2 protein results in decreased susceptibility to sodium arsenite CTD PMID:11455017 sodium arsenite multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with sodium arsenite] results in increased expression of ABCC2 mRNA more ... CTD PMID:25485709 , PMID:26890134 sodium arsenite decreases response to substance EXP 6480464 ABCC2 results in decreased susceptibility to sodium arsenite CTD PMID:16672223 sodium arsenite multiple interactions EXP 6480464 SPDL1 protein promotes the reaction [sodium arsenite results in increased expression of ABCC2 protein] CTD PMID:24391030 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of ABCC2 protein CTD PMID:24391030 sodium chloride multiple interactions ISO RGD:10368 6480464 [Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC2 mRNA CTD PMID:17934960 sodium dichromate affects expression ISO RGD:2366 6480464 sodium bichromate affects the expression of ABCC2 mRNA CTD PMID:22110744 sodium dichromate increases expression ISO RGD:10368 6480464 sodium bichromate results in increased expression of ABCC2 mRNA CTD PMID:22155349 sodium dichromate decreases expression ISO RGD:10368 6480464 sodium bichromate results in decreased expression of ABCC2 mRNA CTD PMID:22155349 sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of ABCC2 mRNA CTD PMID:31734321 sodium hydrogencarbonate increases expression ISO RGD:2366 6480464 Sodium Bicarbonate results in increased expression of ABCC2 mRNA CTD PMID:29126803 sorafenib affects response to substance EXP 6480464 ABCC2 affects the susceptibility to sorafenib CTD PMID:24244338 soybean oil affects expression ISO RGD:2366 6480464 Soybean Oil affects the expression of ABCC2 mRNA CTD PMID:15770074 spironolactone multiple interactions ISO RGD:2366 6480464 [Ethinyl Estradiol co-treated with Spironolactone] results in increased expression of ABCC2 protein more ... CTD PMID:17686906 , PMID:19766108 spironolactone increases expression ISO RGD:2366 6480464 Spironolactone results in increased expression of ABCC2 mRNA, Spironolactone results in increased expression of ABCC2 protein CTD PMID:15652244 more ... stilbene oxide increases expression ISO RGD:2366 6480464 stilbene oxide results in increased expression of ABCC2 mRNA, stilbene oxide results in increased expression of ABCC2 protein CTD PMID:12920174 streptozocin increases expression ISO RGD:2366 6480464 Streptozocin results in increased expression of ABCC2 mRNA CTD PMID:11752103 streptozocin increases expression ISO RGD:10368 6480464 Streptozocin results in increased expression of ABCC2 mRNA, Streptozocin results in increased expression of ABCC2 protein CTD PMID:22531820 , PMID:23319174 succimer increases transport EXP 6480464 ABCC2 results in increased transport of Succimer metabolite CTD PMID:19063911 succimer multiple interactions ISO RGD:2366 6480464 ABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]], ABCC2 protein binds to and results in increased secretion of [Succimer binds to [Mercuric Chloride binds to Cysteine]] CTD PMID:18511429 succimer increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of Succimer metabolite CTD PMID:17940195 sulfasalazine multiple interactions ISO RGD:2366 6480464 [Sulfasalazine results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium CTD PMID:19853032 sulfinpyrazone decreases activity EXP 6480464 Sulfinpyrazone results in decreased activity of ABCC2 protein CTD PMID:14569069 sulforaphane increases expression ISO RGD:2366 6480464 sulforafan results in increased expression of ABCC2 mRNA, sulforafan results in increased expression of ABCC2 protein CTD PMID:11264000 sulforaphane increases expression EXP 6480464 sulforafan results in increased expression of ABCC2 mRNA, sulforafan results in increased expression of ABCC2 protein CTD PMID:11264000 more ... sunitinib increases expression ISO RGD:2366 6480464 sunitinib results in increased expression of ABCC2 mRNA, sunitinib results in increased expression of ABCC2 protein CTD PMID:26797788 tamoxifen affects response to substance EXP 6480464 ABCC2 gene affects the susceptibility to Tamoxifen CTD PMID:20124171 tamoxifen increases expression ISO RGD:2366 6480464 Tamoxifen results in increased expression of ABCC2 mRNA CTD PMID:27765674 taurine increases expression ISO RGD:2366 6480464 Taurine results in increased expression of ABCC2 protein CTD PMID:12706339 tauro-beta-muricholic acid multiple interactions ISO RGD:2366 6480464 tauromuricholic acid results in increased expression of and results in increased activity of ABCC2 protein CTD PMID:12644037 tauro-beta-muricholic acid increases expression ISO RGD:2366 6480464 tauromuricholic acid results in increased expression of ABCC2 protein CTD PMID:11672435 taurochenodeoxycholic acid increases expression ISO RGD:2366 6480464 Taurochenodeoxycholic Acid results in increased expression of ABCC2 protein CTD PMID:11672435 taurocholic acid increases activity ISO RGD:2366 6480464 Taurocholic Acid results in increased activity of ABCC2 protein, Taurocholic Acid results in increased activity of ABCC2 protein modified form CTD PMID:15904671 taurocholic acid increases expression ISO RGD:10368 6480464 Taurocholic Acid results in increased expression of ABCC2 mRNA CTD PMID:27160211 taurocholic acid multiple interactions ISO RGD:2366 6480464 Taurocholic Acid results in increased expression of and results in increased activity of ABCC2 protein CTD PMID:12644037 taurolithocholic acid multiple interactions ISO RGD:2366 6480464 3-chloroacetylindole inhibits the reaction [Taurolithocholic Acid results in decreased activity of ABCC2 protein] more ... CTD PMID:31300867 taurolithocholic acid affects localization ISO RGD:2366 6480464 Taurolithocholic Acid affects the localization of ABCC2 protein CTD PMID:31300867 tauroursodeoxycholic acid increases expression ISO RGD:2366 6480464 ursodoxicoltaurine results in increased expression of ABCC2 protein CTD PMID:11672435 tauroursodeoxycholic acid multiple interactions ISO RGD:2366 6480464 ursodoxicoltaurine results in increased expression of and results in increased activity of ABCC2 protein CTD PMID:12644037 Temocaprilat affects transport ISO RGD:2366 6480464 ABCC2 protein affects the transport of temocaprilat CTD PMID:11348856 , PMID:15507541 Temocaprilat multiple interactions ISO RGD:2366 6480464 Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat] more ... CTD PMID:9067317 Temocaprilat increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of temocaprilat CTD PMID:9067317 temozolomide affects response to substance EXP 6480464 ABCC2 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 tert-butyl hydroperoxide multiple interactions ISO RGD:2366 6480464 Bilirubin analog inhibits the reaction [tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein], tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein CTD PMID:24306262 tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of ABCC2 mRNA CTD PMID:22956110 testosterone multiple interactions ISO RGD:2366 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ABCC2 mRNA] CTD PMID:20032058 testosterone multiple interactions ISO RGD:10368 6480464 [ABCC1 gene mutant form results in increased susceptibility to Testosterone deficiency] which results in increased expression of ABCC2 mRNA, ABCC1 gene mutant form inhibits the reaction [Testosterone deficiency results in increased expression of ABCC2 mRNA] CTD PMID:22522787 testosterone increases expression ISO RGD:10368 6480464 Testosterone deficiency results in increased expression of ABCC2 mRNA CTD PMID:22522787 tetrachloromethane increases expression ISO RGD:10368 6480464 Carbon Tetrachloride results in increased expression of ABCC2 mRNA, Carbon Tetrachloride results in increased expression of ABCC2 protein CTD PMID:15496496 more ... tetrachloromethane multiple interactions ISO RGD:10368 6480464 ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein] more ... CTD PMID:29964319 tetrachloromethane decreases expression ISO RGD:2366 6480464 Carbon Tetrachloride results in decreased expression of ABCC2 protein CTD PMID:12642476 more ... tetrachloromethane decreases activity ISO RGD:2366 6480464 Carbon Tetrachloride results in decreased activity of ABCC2 protein CTD PMID:16899240 tetrachloromethane multiple interactions ISO RGD:2366 6480464 [Carbon Tetrachloride co-treated with Valproic Acid] affects the expression of ABCC2 mRNA CTD PMID:17617793 tetracycline decreases expression ISO RGD:2366 6480464 Tetracycline results in decreased expression of ABCC2 mRNA CTD PMID:27765674 texas red increases transport ISO RGD:2366 6480464 ABCC2 protein results in increased transport of Texas red CTD PMID:32212926 thiacloprid multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with 2-chloro-N-4-chlorobiphenyl-2-ylnicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 thioacetamide increases expression ISO RGD:2366 6480464 Thioacetamide results in increased expression of ABCC2 mRNA CTD PMID:23411599 , PMID:26222700 thiophanate-methyl multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with 2-chloro-N-4-chlorobiphenyl-2-ylnicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 thyroxine decreases abundance ISO RGD:2366 6480464 ABCC2 results in decreased abundance of Thyroxine CTD PMID:19211616 tiagabine increases expression ISO RGD:2366 6480464 tiagabine results in increased expression of ABCC2 protein CTD PMID:18473823 ticlopidine decreases activity EXP 6480464 Ticlopidine results in decreased activity of ABCC2 protein CTD PMID:22646477 ticlopidine increases expression ISO RGD:2366 6480464 Ticlopidine results in increased expression of ABCC2 mRNA CTD PMID:27765674 Tolvaptan decreases activity EXP 6480464 tolvaptan metabolite results in decreased activity of ABCC2 protein CTD PMID:26507107 topiramate increases expression ISO RGD:2366 6480464 topiramate results in increased expression of ABCC2 protein CTD PMID:18473823 topotecan increases expression EXP 6480464 Topotecan results in increased expression of ABCC2 protein CTD PMID:20457140 topotecan multiple interactions EXP 6480464 [chrysin results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan, [verlukast results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan CTD PMID:20457140 trans-piceid affects export EXP 6480464 ABCC2 protein affects the export of polydatin CTD PMID:15686436 trichostatin A decreases expression EXP 6480464 trichostatin A results in decreased expression of ABCC2 mRNA, trichostatin A results in decreased expression of ABCC2 protein CTD PMID:10691972 triclosan increases expression EXP 6480464 Triclosan results in increased expression of ABCC2 mRNA CTD PMID:29849464 trimethylarsine oxide increases expression ISO RGD:2366 6480464 trimethylarsine oxide results in increased expression of ABCC2 mRNA, trimethylarsine oxide results in increased expression of ABCC2 protein CTD PMID:16436460 triphenyl phosphate increases expression ISO RGD:2366 6480464 triphenyl phosphate results in increased expression of ABCC2 mRNA CTD PMID:30589522 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of ABCC2 mRNA CTD PMID:19022234 troglitazone decreases activity EXP 6480464 troglitazone results in decreased activity of ABCC2 protein CTD PMID:22646477 troglitazone multiple interactions EXP 6480464 [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of troglitazone analog CTD PMID:19628752 tyrphostin AG 1478 multiple interactions ISO RGD:2366 6480464 RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein] CTD PMID:25813982 uranium atom multiple interactions ISO RGD:2366 6480464 [Acetaminophen co-treated with Uranium analog] results in increased expression of ABCC2 mRNA, Uranium analog promotes the reaction [Acetaminophen results in increased expression of ABCC2 mRNA] CTD PMID:17126469 urethane decreases expression EXP 6480464 Urethane results in decreased expression of ABCC2 mRNA CTD PMID:28818685 ursodeoxycholic acid increases expression EXP 6480464 Ursodeoxycholic Acid results in increased expression of ABCC2, Ursodeoxycholic Acid results in increased expression of ABCC2 protein CTD PMID:15956029 , PMID:16952291 ursodeoxycholic acid increases expression ISO RGD:10368 6480464 Ursodeoxycholic Acid results in increased expression of ABCC2 mRNA, Ursodeoxycholic Acid results in increased expression of ABCC2 protein CTD PMID:11438506 more ... ursodeoxycholic acid increases expression ISO RGD:2366 6480464 Ursodeoxycholic Acid results in increased expression of ABCC2 mRNA, Ursodeoxycholic Acid results in increased expression of ABCC2 protein CTD PMID:19067394 ursodeoxycholic acid multiple interactions ISO RGD:10368 6480464 NFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC2 mRNA], NFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC2 protein] CTD PMID:18687751 ursodeoxycholic acid increases activity ISO RGD:2366 6480464 Ursodeoxycholic Acid results in increased activity of ABCC2 protein CTD PMID:15843489 ursodeoxycholic acid multiple interactions ISO RGD:2366 6480464 ABCC2 affects the reaction [Ursodeoxycholic Acid results in increased secretion of Nitric Oxide] more ... CTD PMID:15843489 more ... ursodeoxycholic acid affects expression ISO RGD:2366 6480464 Ursodeoxycholic Acid affects the expression of ABCC2 mRNA, Ursodeoxycholic Acid affects the expression of ABCC2 protein CTD PMID:12606635 vadimezan affects transport EXP 6480464 ABCC2 protein affects the transport of vadimezan analog CTD PMID:15282097 vadimezan affects export EXP 6480464 ABCC2 protein affects the export of vadimezan metabolite CTD PMID:15784341 valdecoxib increases expression ISO RGD:2366 6480464 valdecoxib results in increased expression of ABCC2 mRNA CTD PMID:24136188 valproic acid multiple interactions ISO RGD:2366 6480464 [Carbon Tetrachloride co-treated with Valproic Acid] affects the expression of ABCC2 mRNA CTD PMID:17617793 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of ABCC2 mRNA CTD PMID:29501571 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of ABCC2 gene CTD PMID:29501571 valproic acid increases expression ISO RGD:10368 6480464 Valproic Acid results in increased expression of ABCC2 mRNA CTD PMID:27160211 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of ABCC2 mRNA, Valproic Acid results in increased expression of ABCC2 protein CTD PMID:23527032 , PMID:29501571 valproic acid decreases expression ISO RGD:2366 6480464 Valproic Acid results in decreased expression of ABCC2 mRNA CTD PMID:21318169 , PMID:27765674 vancomycin multiple interactions ISO RGD:10368 6480464 [Vancomycin co-treated with Imipenem] affects the expression of ABCC2 mRNA CTD PMID:24657338 vancomycin decreases expression ISO RGD:2366 6480464 Vancomycin results in decreased expression of ABCC2 mRNA, Vancomycin results in decreased expression of ABCC2 protein CTD PMID:29964132 vancomycin multiple interactions ISO RGD:2366 6480464 JBP 485 inhibits the reaction [Vancomycin results in decreased expression of ABCC2 mRNA], JBP 485 inhibits the reaction [Vancomycin results in decreased expression of ABCC2 protein] CTD PMID:29964132 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate] CTD PMID:16636798 vincaleukoblastine affects transport EXP 6480464 ABCC2 protein affects the transport of Vinblastine CTD PMID:15849751 , PMID:9525973 vincaleukoblastine decreases response to substance ISO RGD:2366 6480464 ABCC2 protein results in decreased susceptibility to Vinblastine CTD PMID:11455017 vincaleukoblastine multiple interactions EXP 6480464 [isopropyl 5 more ... CTD PMID:15849751 , PMID:25844889 vincristine multiple interactions EXP 6480464 [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA more ... CTD PMID:15896345 , PMID:19944135 vincristine decreases response to substance EXP 6480464 ABCC2 protein results in decreased susceptibility to Vincristine CTD PMID:15896345 , PMID:22095822 vincristine affects export EXP 6480464 ABCC2 protein affects the export of Vincristine CTD PMID:15896345 vitamin E multiple interactions ISO RGD:2366 6480464 [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 wortmannin affects localization ISO RGD:2366 6480464 wortmannin affects the localization of ABCC2 protein CTD PMID:12702492 wortmannin multiple interactions ISO RGD:2366 6480464 Wortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein], Wortmannin inhibits the reaction [Taurolithocholic Acid results in decreased activity of and affects the localization of ABCC2 protein] CTD PMID:20815017 , PMID:31300867 Y-27632 increases expression EXP 6480464 Y 27632 results in increased expression of ABCC2 mRNA CTD PMID:20878077 Yangonin multiple interactions ISO RGD:10368 6480464 yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA], yangonin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein] CTD PMID:29660435 yohimbine multiple interactions ISO RGD:10368 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of ABCC2 mRNA CTD PMID:19580841 zearalenone multiple interactions EXP 6480464 verlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone], Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] CTD PMID:19647055 zearalenone increases transport EXP 6480464 ABCC2 protein results in increased transport of Zearalenone CTD PMID:19647055 ziram multiple interactions ISO RGD:10368 6480464 [Dietary Fats co-treated with 2-chloro-N-4-chlorobiphenyl-2-ylnicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781
