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Gene: ABCC2 (ATP binding cassette subfamily C member 2) Homo sapiens
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Symbol: ABCC2
Name: ATP binding cassette subfamily C member 2
Description: Exhibits ATPase-coupled transmembrane transporter activity and xenobiotic transmembrane transporter activity. Involved in bile acid and bile salt transport. Localizes to the apical plasma membrane and cell surface. Implicated in bilirubin metabolic disorder (multiple); carcinoma (multiple); drug-induced hepatitis; leukemia (multiple); and non-alcoholic fatty liver disease. Biomarker of cholestasis and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABC30; ATP-binding cassette sub-family C member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; canalicular multidrug resistance protein; canalicular multispecific organic anion transporter 1; CMOAT; cMRP; DJS; KIAA1010; MRP2; multidrug resistance-associated protein 2
Orthologs:
Mus musculus (house mouse) : Abcc2 (ATP-binding cassette, sub-family C (CFTR/MRP), member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcc2 (ATP binding cassette subfamily C member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc2 (ATP binding cassette subfamily C member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC2 (ATP binding cassette subfamily C member 2)
Canis lupus familiaris (dog) : ABCC2 (ATP binding cassette subfamily C member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc2 (ATP binding cassette subfamily C member 2)
Sus scrofa (pig) : ABCC2 (ATP binding cassette subfamily C member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381099,782,602 - 99,853,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710101,542,457 - 101,611,662 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610101,532,493 - 101,601,571 (+)NCBINCBI36hg18NCBI36
Build 3410101,532,562 - 101,601,571NCBI
Celera1095,279,806 - 95,349,643 (+)NCBI
Cytogenetic Map10q24.2NCBI
HuRef1095,169,835 - 95,239,503 (+)NCBIHuRef
CHM1_110101,824,803 - 101,894,655 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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