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Gene: FBLN1 (fibulin 1) Homo sapiens
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Symbol: FBLN1
Name: fibulin 1
Description: Exhibits several functions, including fibrinogen binding activity; fibronectin binding activity; and protein C-terminus binding activity. Involved in several processes, including negative regulation of cell communication; negative regulation of transformation of host cell by virus; and regulation of cell-substrate adhesion. Localizes to elastic fiber and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FBLN; FIBL1; fibulin-1
Orthologs:
Mus musculus (house mouse) : Fbln1 (fibulin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbln1 (fibulin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbln1 (fibulin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBLN1 (fibulin 1)
Canis lupus familiaris (dog) : FBLN1 (fibulin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbln1 (fibulin 1)
Sus scrofa (pig) : FBLN1 (fibulin 1)
Chlorocebus sabaeus (African green monkey) : FBLN1 (fibulin 1)
Heterocephalus glaber (naked mole-rat) : Fbln1 (fibulin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2245,502,238 - 45,601,135 (+)EnsemblGRCh38hg38GRCh38
GRCh382245,502,883 - 45,601,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372245,898,719 - 45,997,014 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362244,277,383 - 44,375,678 (+)NCBINCBI36hg18NCBI36
Build 342244,219,255 - 44,275,128NCBI
Celera2229,809,689 - 29,909,644 (+)NCBI
Cytogenetic Map22q13.31NCBI
HuRef2228,859,953 - 28,942,412 (+)NCBIHuRef
CHM1_12245,857,451 - 45,955,744 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FBLN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318572
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.