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Gene: QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1) Homo sapiens
Symbol: QTRT1
Name: queuine tRNA-ribosyltransferase catalytic subunit 1
Description: This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FP3235; guanine insertion enzyme; queuine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 1; queuine tRNA-ribosyltransferase catalytic subunit; TGT; TGT, 43-KD subunit; TGT, catalytic subunit; TGUT; tRNA-guanine transglycosylase
Related Pseudogenes: QTRT1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381910,701,439 - 10,713,365 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,812,112 - 10,824,043 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,673,131 - 10,685,040 (+)NCBINCBI36hg18NCBI36
Build 341910,673,130 - 10,685,040NCBI
Celera1910,706,867 - 10,718,794 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,389,232 - 10,401,116 (+)NCBIHuRef
CHM1_11910,813,359 - 10,825,254 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on QTRT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732681
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.