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Gene: CDC42BPA (CDC42 binding protein kinase alpha) Homo sapiens
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Symbol: CDC42BPA
Name: CDC42 binding protein kinase alpha
RGD ID: 1351605
Description: Exhibits several functions, including ATP binding activity; identical protein binding activity; and magnesium ion binding activity. Involved in actin cytoskeleton organization; cell migration; and protein phosphorylation. Localizes to actomyosin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC42 binding protein kinase alpha (DMPK-like); CDC42 binding protein kinase beta; CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha; CDC42-binding protein kinase alpha (DMPK-like); DKFZp686L1738; DKFZp686P1738; DMPK-like alpha; FLJ23347; KIAA0451; MRCK; MRCK alpha; MRCKA; myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; PK428; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase; serine/threonine-protein kinase MRCK alpha
Orthologs:
Mus musculus (house mouse) : Cdc42bpa (CDC42 binding protein kinase alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc42bpa (CDC42 binding protein kinase alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc42bpa (CDC42 binding protein kinase alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC42BPA (CDC42 binding protein kinase alpha)
Canis lupus familiaris (dog) : CDC42BPA (CDC42 binding protein kinase alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc42bpa (CDC42 binding protein kinase alpha)
Sus scrofa (pig) : CDC42BPA (CDC42 binding protein kinase alpha)
Chlorocebus sabaeus (African green monkey) : CDC42BPA (CDC42 binding protein kinase alpha)
Heterocephalus glaber (naked mole-rat) : Cdc42bpa (CDC42 binding protein kinase alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1226,989,865 - 227,318,474 (-)EnsemblGRCh38hg38GRCh38
GRCh381226,989,858 - 227,318,502 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371227,177,566 - 227,506,193 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,244,189 - 225,572,449 (-)NCBINCBI36hg18NCBI36
Build 341223,486,787 - 223,812,561NCBI
Celera1200,368,385 - 200,714,137 (-)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1197,694,156 - 198,022,367 (-)NCBIHuRef
CHM1_11228,450,048 - 228,778,008 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC42BPA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351605
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.