RAD23A (RAD23 homolog A, nucleotide excision repair protein) - Rat Genome Database
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Gene: RAD23A (RAD23 homolog A, nucleotide excision repair protein) Homo sapiens
Analyze
Symbol: RAD23A
Name: RAD23 homolog A, nucleotide excision repair protein
RGD ID: 1320493
HGNC Page HGNC
Description: Exhibits kinase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-specific protease binding activity. Involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of viral genome replication; and protein destabilization. Localizes to several cellular components, including centriolar satellite; cytosol; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HHR23A; HR23A; MGC111083; RAD23 homolog A; RAD23, yeast homolog, A; UV excision repair protein RAD23 homolog A
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1912,945,855 - 12,953,642 (+)EnsemblGRCh38hg38GRCh38
GRCh381912,945,846 - 12,953,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,056,628 - 13,064,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,917,654 - 12,925,455 (+)NCBINCBI36hg18NCBI36
Build 341912,917,653 - 12,925,455NCBI
Celera1912,946,385 - 12,954,184 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,628,527 - 12,636,354 (+)NCBIHuRef
CHM1_11913,057,148 - 13,064,977 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (ISO)
amphibole asbestos  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
carmustine  (EXP)
chlorogenic acid  (EXP)
cisplatin  (EXP)
clofibrate  (ISO)
copper(II) sulfate  (EXP)
CU-O LINKAGE  (EXP)
cyclosporin A  (EXP)
cytarabine  (EXP)
diarsenic trioxide  (EXP)
dicrotophos  (EXP)
elemental selenium  (EXP)
endosulfan  (ISO)
finasteride  (ISO)
flutamide  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
hydroxyurea  (ISO)
indirubin-3'-monoxime  (EXP)
kainic acid  (ISO)
kojic acid  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
Osajin  (EXP)
oxaliplatin  (ISO)
paclitaxel  (ISO)
pentachlorophenol  (EXP)
pirinixic acid  (ISO)
Pomiferin  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (EXP)
Rosavin  (EXP)
rotenone  (ISO)
selenium atom  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP)
sunitinib  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (EXP)
titanium dioxide  (ISO)
toluene  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
troglitazone  (EXP)
tunicamycin  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)
zinc pyrithione  (EXP)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7851894   PMID:8037842   PMID:8168482   PMID:8692695   PMID:8808275   PMID:9153201   PMID:9164480   PMID:9371639   PMID:9372924   PMID:9490418   PMID:9636371   PMID:9846873  
PMID:10373495   PMID:10488153   PMID:10854423   PMID:10915768   PMID:11087358   PMID:11196199   PMID:11259200   PMID:11426943   PMID:11571271   PMID:11788722   PMID:11827521   PMID:12079361  
PMID:12200120   PMID:12477932   PMID:12643283   PMID:12970176   PMID:14557549   PMID:14621999   PMID:14645509   PMID:14706819   PMID:15004330   PMID:15057824   PMID:15064742   PMID:15263005  
PMID:15321727   PMID:15342556   PMID:15489334   PMID:15949443   PMID:16007098   PMID:16105547   PMID:16120388   PMID:16189514   PMID:16405905   PMID:16430867   PMID:16712842   PMID:16713569  
PMID:16924240   PMID:16990800   PMID:17098253   PMID:17408689   PMID:17426036   PMID:17935801   PMID:18054791   PMID:18234089   PMID:18485873   PMID:18514189   PMID:18654987   PMID:18976975  
PMID:19013454   PMID:19161404   PMID:19285159   PMID:19292762   PMID:19458171   PMID:19615732   PMID:19620964   PMID:19724136   PMID:19913121   PMID:20012529   PMID:20059542   PMID:20496165  
PMID:20522537   PMID:20614012   PMID:20628086   PMID:20804422   PMID:21047872   PMID:21163940   PMID:21318276   PMID:21516116   PMID:21676658   PMID:21742020   PMID:21784850   PMID:21873635  
PMID:21900206   PMID:22315970   PMID:22428841   PMID:22542781   PMID:22575648   PMID:22863883   PMID:22939629   PMID:22970133   PMID:23105008   PMID:23260144   PMID:23314748   PMID:23357418  
PMID:23443559   PMID:23503661   PMID:23562397   PMID:23671107   PMID:23823328   PMID:24130170   PMID:24140708   PMID:24258024   PMID:24318982   PMID:24811749   PMID:25187353   PMID:25260751  
PMID:25277244   PMID:25281560   PMID:25311859   PMID:25416956   PMID:25752573   PMID:26216987   PMID:26296656   PMID:26344197   PMID:27432908   PMID:27534557   PMID:27613096   PMID:27771451  
PMID:28190767   PMID:28846114   PMID:29117863   PMID:29263404   PMID:29426014   PMID:29568061   PMID:29997244   PMID:30455355   PMID:30659753   PMID:31467278   PMID:31487504   PMID:31515488  
PMID:31536960   PMID:31699778   PMID:32296183   PMID:32814053  


Genomics

Comparative Map Data
RAD23A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1912,945,855 - 12,953,642 (+)EnsemblGRCh38hg38GRCh38
GRCh381912,945,846 - 12,953,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,056,628 - 13,064,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,917,654 - 12,925,455 (+)NCBINCBI36hg18NCBI36
Build 341912,917,653 - 12,925,455NCBI
Celera1912,946,385 - 12,954,184 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,628,527 - 12,636,354 (+)NCBIHuRef
CHM1_11913,057,148 - 13,064,977 (+)NCBICHM1_1
Rad23a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,561,540 - 85,567,361 (-)NCBIGRCm39mm39
GRCm38884,834,927 - 84,840,652 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,834,019 - 84,840,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv37887,358,551 - 87,364,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv36887,724,757 - 87,730,746 (-)NCBImm8
Celera889,133,785 - 89,139,795 (-)NCBICelera
Cytogenetic Map8C3NCBI
Rad23a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01925,949,488 - 25,956,677 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,949,490 - 25,955,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,925,111 - 36,931,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,971,070 - 24,976,901 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,975,895 - 24,981,725 (+)NCBI
Celera1922,871,740 - 22,877,567 (+)NCBICelera
Cytogenetic Map19q11NCBI
Rad23a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,991,479 - 32,000,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,991,478 - 31,997,277 (+)NCBIChiLan1.0ChiLan1.0
RAD23A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11913,250,718 - 13,258,482 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1913,250,718 - 13,258,482 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01912,508,232 - 12,516,068 (+)NCBIMhudiblu_PPA_v0panPan3
RAD23A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2049,241,358 - 49,250,039 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12049,244,330 - 49,250,058 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rad23a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366592,001,356 - 2,007,520 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD23A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,084,856 - 66,096,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,090,089 - 66,096,477 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,289,387 - 66,295,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD23A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl611,625,458 - 11,637,419 (+)Ensembl
ChlSab1.1611,625,464 - 11,633,922 (+)NCBI
Rad23a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624901515,761 - 522,845 (+)NCBI

Position Markers
D19S631E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371913,064,294 - 13,064,412UniSTSGRCh37
Build 361912,925,294 - 12,925,412RGDNCBI36
Celera1912,954,023 - 12,954,141RGD
Cytogenetic Map19p13.2UniSTS
HuRef1912,636,191 - 12,636,309UniSTS
SHGC-31478  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371913,063,890 - 13,064,099UniSTSGRCh37
Build 361912,924,890 - 12,925,099RGDNCBI36
Celera1912,953,619 - 12,953,828RGD
Cytogenetic Map19p13.2UniSTS
HuRef1912,635,787 - 12,635,996UniSTS
Stanford-G3 RH Map19354.0UniSTS
GeneMap99-G3 RH Map19354.0UniSTS
STS-M84739  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X27,769,716 - 27,770,249UniSTSGRCh37
GRCh371913,054,738 - 13,054,982UniSTSGRCh37
Build 36X27,679,637 - 27,680,170RGDNCBI36
CeleraX31,898,190 - 31,898,723RGD
Celera1912,944,469 - 12,944,713UniSTS
Cytogenetic Map19p13.3-p13.2UniSTS
Cytogenetic Map19p13.2UniSTS
HuRef1912,626,638 - 12,626,881UniSTS
GeneMap99-GB4 RH Map1971.27UniSTS
STS-D21235  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371913,064,246 - 13,064,427UniSTSGRCh37
Build 361912,925,246 - 12,925,427RGDNCBI36
Celera1912,953,975 - 12,954,156RGD
Cytogenetic Map19p13.2UniSTS
HuRef1912,636,143 - 12,636,324UniSTS
GeneMap99-GB4 RH Map1971.17UniSTS
NCBI RH Map1987.9UniSTS
RH41793  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371913,064,237 - 13,064,427UniSTSGRCh37
Build 361912,925,237 - 12,925,427RGDNCBI36
Celera1912,953,966 - 12,954,156RGD
Cytogenetic Map19p13.2UniSTS
HuRef1912,636,134 - 12,636,324UniSTS
GeneMap99-GB4 RH Map1974.32UniSTS
RAD23A  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371913,058,688 - 13,058,787UniSTSGRCh37
Build 361912,919,688 - 12,919,787RGDNCBI36
Celera1912,948,417 - 12,948,516RGD
HuRef1912,630,585 - 12,630,684UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4173
Count of miRNA genes:737
Interacting mature miRNAs:851
Transcripts:ENST00000316856, ENST00000541222, ENST00000586375, ENST00000586534, ENST00000588329, ENST00000588826, ENST00000590881, ENST00000591467, ENST00000591499, ENST00000592268, ENST00000593114
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 57 57 5 57
Medium 2432 2961 1722 621 1947 463 4298 2112 3696 418 1443 1608 171 1204 2731 4
Low 23 1 1 1 1 24 12
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_072976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AD000092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF549209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI057203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI081136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI832600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP213821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX448989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB456593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000316856   ⟹   ENSP00000321365
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,876 - 12,953,623 (+)Ensembl
RefSeq Acc Id: ENST00000586375   ⟹   ENSP00000466226
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,948,689 - 12,953,405 (+)Ensembl
RefSeq Acc Id: ENST00000586534   ⟹   ENSP00000467024
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,862 - 12,953,642 (+)Ensembl
RefSeq Acc Id: ENST00000588329
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,866 - 12,949,282 (+)Ensembl
RefSeq Acc Id: ENST00000588826
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,946,005 - 12,949,576 (+)Ensembl
RefSeq Acc Id: ENST00000590881   ⟹   ENSP00000467628
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,949,084 - 12,953,595 (+)Ensembl
RefSeq Acc Id: ENST00000591467
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,952,364 - 12,952,990 (+)Ensembl
RefSeq Acc Id: ENST00000591499   ⟹   ENSP00000466243
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,855 - 12,953,269 (+)Ensembl
RefSeq Acc Id: ENST00000592268   ⟹   ENSP00000468674
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,892 - 12,953,591 (+)Ensembl
RefSeq Acc Id: ENST00000593114   ⟹   ENSP00000466968
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,894 - 12,953,613 (+)Ensembl
RefSeq Acc Id: ENST00000651137   ⟹   ENSP00000498473
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1912,945,859 - 12,953,640 (+)Ensembl
RefSeq Acc Id: NM_001270362   ⟹   NP_001257291
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,862 - 12,953,642 (+)NCBI
GRCh371913,056,628 - 13,064,457 (+)NCBI
HuRef1912,628,527 - 12,636,354 (+)NCBI
CHM1_11913,057,148 - 13,064,977 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270363   ⟹   NP_001257292
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,862 - 12,953,642 (+)NCBI
GRCh371913,056,628 - 13,064,457 (+)NCBI
HuRef1912,628,527 - 12,636,354 (+)NCBI
CHM1_11913,057,148 - 13,064,977 (+)NCBI
Sequence:
RefSeq Acc Id: NM_005053   ⟹   NP_005044
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,862 - 12,953,642 (+)NCBI
GRCh371913,056,628 - 13,064,457 (+)NCBI
Build 361912,917,654 - 12,925,455 (+)NCBI Archive
HuRef1912,628,527 - 12,636,354 (+)NCBI
CHM1_11913,057,148 - 13,064,977 (+)NCBI
Sequence:
RefSeq Acc Id: NR_072976
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,862 - 12,953,642 (+)NCBI
GRCh371913,056,628 - 13,064,457 (+)NCBI
HuRef1912,628,527 - 12,636,354 (+)NCBI
CHM1_11913,057,148 - 13,064,977 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024451631   ⟹   XP_024307399
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,846 - 12,953,642 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_005044   ⟸   NM_005053
- Peptide Label: isoform 1
- UniProtKB: P54725 (UniProtKB/Swiss-Prot),   A0A024R7G8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257292   ⟸   NM_001270363
- Peptide Label: isoform 3
- UniProtKB: P54725 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257291   ⟸   NM_001270362
- Peptide Label: isoform 2
- UniProtKB: P54725 (UniProtKB/Swiss-Prot),   A8K1J3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024307399   ⟸   XM_024451631
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000467024   ⟸   ENST00000586534
RefSeq Acc Id: ENSP00000466226   ⟸   ENST00000586375
RefSeq Acc Id: ENSP00000498473   ⟸   ENST00000651137
RefSeq Acc Id: ENSP00000467628   ⟸   ENST00000590881
RefSeq Acc Id: ENSP00000466243   ⟸   ENST00000591499
RefSeq Acc Id: ENSP00000321365   ⟸   ENST00000316856
RefSeq Acc Id: ENSP00000468674   ⟸   ENST00000592268
RefSeq Acc Id: ENSP00000466968   ⟸   ENST00000593114
Protein Domains
UBA   Ubiquitin-like

Promoters
RGD ID:6795972
Promoter ID:HG_KWN:29044
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_005053,   UC002MVX.1,   UC002MVY.1,   UC002MVZ.1,   UC002MWA.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361912,916,676 - 12,917,697 (+)MPROMDB
RGD ID:6851420
Promoter ID:EP73510
Type:initiation region
Name:HS_RAD23A
Description:RAD23 homolog A (S. cerevisiae).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361912,917,691 - 12,917,751EPD
RGD ID:7238755
Promoter ID:EPDNEW_H25123
Type:initiation region
Name:RAD23A_2
Description:RAD23 homolog A, nucleotide excision repair protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25124  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,943,538 - 12,943,598EPDNEW
RGD ID:7238757
Promoter ID:EPDNEW_H25124
Type:initiation region
Name:RAD23A_1
Description:RAD23 homolog A, nucleotide excision repair protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25123  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381912,945,862 - 12,945,922EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19p13.2-13.13(chr19:8831147-13331227)x3 copy number gain See cases [RCV000052908] Chr19:8831147..13331227 [GRCh38]
Chr19:8941823..13442041 [GRCh37]
Chr19:8802823..13303041 [NCBI36]
Chr19:19p13.2-13.13
likely pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:10315258-14048994)x3 copy number gain See cases [RCV000052909] Chr19:10315258..14048994 [GRCh38]
Chr19:10425934..14159806 [GRCh37]
Chr19:10286934..14020806 [NCBI36]
Chr19:19p13.2-13.12
pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:12132052-14751798)x3 copy number gain See cases [RCV000052910] Chr19:12132052..14751798 [GRCh38]
Chr19:12242867..14862610 [GRCh37]
Chr19:12103867..14723610 [NCBI36]
Chr19:19p13.2-13.12
pathogenic
GRCh38/hg38 19p13.13(chr19:12850595-13290954)x3 copy number gain See cases [RCV000052911] Chr19:12850595..13290954 [GRCh38]
Chr19:12961409..13401768 [GRCh37]
Chr19:12822409..13262768 [NCBI36]
Chr19:19p13.13
pathogenic
GRCh38/hg38 19p13.13(chr19:12813597-13119698)x3 copy number gain See cases [RCV000054144] Chr19:12813597..13119698 [GRCh38]
Chr19:12924411..13230512 [GRCh37]
Chr19:12785411..13091512 [NCBI36]
Chr19:19p13.13
uncertain significance
GRCh38/hg38 19p13.2-13.12(chr19:11227942-14532135)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053944]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053944]|See cases [RCV000053944] Chr19:11227942..14532135 [GRCh38]
Chr19:11338618..14642947 [GRCh37]
Chr19:11199618..14503947 [NCBI36]
Chr19:19p13.2-13.12
pathogenic
GRCh38/hg38 19p13.2-13.13(chr19:11517825-13225287)x1 copy number loss See cases [RCV000053945] Chr19:11517825..13225287 [GRCh38]
Chr19:11628640..13336101 [GRCh37]
Chr19:11489640..13197101 [NCBI36]
Chr19:19p13.2-13.13
pathogenic
NM_005053.3(RAD23A):c.754C>T (p.Pro252Ser) single nucleotide variant Malignant melanoma [RCV000071939] Chr19:12949349 [GRCh38]
Chr19:13060163 [GRCh37]
Chr19:12921163 [NCBI36]
Chr19:19p13.13
not provided
NM_052850.3(GADD45GIP1):c.183C>T (p.Phe61=) single nucleotide variant Malignant melanoma [RCV000063435] Chr19:12957030 [GRCh38]
Chr19:13067844 [GRCh37]
Chr19:12928844 [NCBI36]
Chr19:19p13.13
not provided
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:12580427-14742673)x1 copy number loss See cases [RCV000135937] Chr19:12580427..14742673 [GRCh38]
Chr19:12691241..14853485 [GRCh37]
Chr19:12552241..14714485 [NCBI36]
Chr19:19p13.2-13.12
pathogenic|likely pathogenic
GRCh38/hg38 19p13.2-13.12(chr19:11525163-14155021)x1 copy number loss See cases [RCV000136909] Chr19:11525163..14155021 [GRCh38]
Chr19:11635978..14265833 [GRCh37]
Chr19:11496978..14126833 [NCBI36]
Chr19:19p13.2-13.12
pathogenic
GRCh38/hg38 19p13.2-13.13(chr19:10319474-13777860)x1 copy number loss See cases [RCV000141568] Chr19:10319474..13777860 [GRCh38]
Chr19:10430150..13888674 [GRCh37]
Chr19:10291150..13749674 [NCBI36]
Chr19:19p13.2-13.13
pathogenic
GRCh37/hg19 19p13.2(chr19:12204632-13497073)x1 copy number loss See cases [RCV000449161] Chr19:12204632..13497073 [GRCh37]
Chr19:19p13.2
pathogenic
GRCh37/hg19 19p13.2-13.12(chr19:9678768-14853426) copy number gain See cases [RCV000446985] Chr19:9678768..14853426 [GRCh37]
Chr19:19p13.2-13.12
pathogenic
GRCh37/hg19 19p13.2-13.12(chr19:12574343-14726197)x1 copy number loss See cases [RCV000511130] Chr19:12574343..14726197 [GRCh37]
Chr19:19p13.2-13.12
pathogenic
GRCh37/hg19 19p13.2-13.12(chr19:11608072-14543046)x3 copy number gain See cases [RCV000511013] Chr19:11608072..14543046 [GRCh37]
Chr19:19p13.2-13.12
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.2(chr19:12354642-13424014)x1 copy number loss not provided [RCV000846538] Chr19:12354642..13424014 [GRCh37]
Chr19:19p13.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9812 AgrOrtholog
COSMIC RAD23A COSMIC
Ensembl Genes ENSG00000179262 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000321365 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000466226 UniProtKB/TrEMBL
  ENSP00000466243 UniProtKB/TrEMBL
  ENSP00000466968 UniProtKB/TrEMBL
  ENSP00000467024 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000467628 UniProtKB/TrEMBL
  ENSP00000468674 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000498473 UniProtKB/TrEMBL
Ensembl Transcript ENST00000316856 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000586375 UniProtKB/TrEMBL
  ENST00000586534 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000590881 UniProtKB/TrEMBL
  ENST00000591499 UniProtKB/TrEMBL
  ENST00000592268 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000593114 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000651137 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000179262 GTEx
HGNC ID HGNC:9812 ENTREZGENE
Human Proteome Map RAD23A Human Proteome Map
InterPro Rad23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAD23A/B_UBA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STI1_HS-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  XPC-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XPC-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5886 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5886 ENTREZGENE
OMIM 600061 OMIM
Pfam UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ubiquitin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XPC-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA34172 PharmGKB
PRINTS RAD23PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART STI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF101238 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs rad23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Hs.643267 ENTREZGENE
UniProt A0A024R7G8 ENTREZGENE, UniProtKB/TrEMBL
  A0A494C0B4_HUMAN UniProtKB/TrEMBL
  A8K1J3 ENTREZGENE, UniProtKB/TrEMBL
  K7ELU6_HUMAN UniProtKB/TrEMBL
  K7ELW1_HUMAN UniProtKB/TrEMBL
  K7ENJ0_HUMAN UniProtKB/TrEMBL
  K7EQ16_HUMAN UniProtKB/TrEMBL
  P54725 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary K7ESE3 UniProtKB/Swiss-Prot
  Q59EU8 UniProtKB/Swiss-Prot
  Q5M7Z1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-14 RAD23A  RAD23 homolog A, nucleotide excision repair protein  RAD23A  RAD23 homolog A (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED