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Gene: HPGDS (hematopoietic prostaglandin D synthase) Homo sapiens
Symbol: HPGDS
Name: hematopoietic prostaglandin D synthase
Description: Exhibits metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Involved in prostaglandin metabolic process. Localizes to cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-transferase sigma; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; GST class-sigma; GSTS; GSTS1; GSTS1-1; hematopoietic prostaglandin D2 synthase; PGD2; PGDS; prostaglandin-H2 D-isomerase
Mus musculus (house mouse) : Hpgds (hematopoietic prostaglandin D synthase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hpgds (hematopoietic prostaglandin D synthase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HPGDS (hematopoietic prostaglandin D synthase)
Canis lupus familiaris (dog) : HPGDS (hematopoietic prostaglandin D synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgds (hematopoietic prostaglandin D synthase)
Sus scrofa (pig) : HPGDS (hematopoietic prostaglandin D synthase)
Chlorocebus sabaeus (African green monkey) : HPGDS (hematopoietic prostaglandin D synthase)
Heterocephalus glaber (naked mole-rat) : Hpgds (hematopoietic prostaglandin D synthase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl494,298,535 - 94,342,876 (-)EnsemblGRCh38hg38GRCh38
GRCh38494,298,535 - 94,342,876 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37495,219,707 - 95,264,027 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36495,438,730 - 95,483,050 (-)NCBINCBI36hg18NCBI36
Build 34495,577,633 - 95,612,968NCBI
Celera492,516,831 - 92,561,280 (-)NCBI
Cytogenetic Map4q22.3NCBI
HuRef490,957,458 - 91,001,835 (-)NCBIHuRef
CHM1_1495,196,420 - 95,241,397 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HPGDS
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732845
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.