COX7A1 (cytochrome c oxidase subunit 7A1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: COX7A1 (cytochrome c oxidase subunit 7A1) Homo sapiens
Analyze
Symbol: COX7A1
Name: cytochrome c oxidase subunit 7A1
RGD ID: 1348243
HGNC Page HGNC:2287
Description: Predicted to enable oxidoreductase activity. Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial respirasome assembly and regulation of oxidative phosphorylation. Located in mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: COX7A; COX7AH; COX7AM; cytochrome c oxidase subunit 7A1, mitochondrial; cytochrome c oxidase subunit VIIa heart/muscle isoform; cytochrome c oxidase subunit VIIa polypeptide 1 (muscle); cytochrome c oxidase subunit VIIa-H; cytochrome c oxidase subunit VIIa-heart; cytochrome c oxidase subunit VIIa-M; cytochrome c oxidase subunit VIIa-muscle
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381936,150,922 - 36,152,447 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1936,150,922 - 36,152,449 (-)EnsemblGRCh38hg38GRCh38
GRCh371936,641,824 - 36,643,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361941,333,664 - 41,335,611 (-)NCBINCBI36Build 36hg18NCBI36
Build 341941,333,663 - 41,335,611NCBI
Celera1933,355,996 - 33,357,943 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1933,147,296 - 33,149,244 (-)NCBIHuRef
CHM1_11936,643,830 - 36,645,777 (-)NCBICHM1_1
T2T-CHM13v2.01938,696,740 - 38,698,266 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
aspartame  (ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
corn oil  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (EXP)
elemental selenium  (EXP)
fenthion  (ISO)
furan  (ISO)
gentamycin  (ISO)
graphite  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
Licarin A  (ISO)
lipopolysaccharide  (EXP)
maneb  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (EXP)
rac-lactic acid  (EXP)
resveratrol  (ISO)
selenium atom  (EXP)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triclosan  (EXP)
valproic acid  (EXP)
vancomycin  (ISO)
XL147  (ISO)
zidovudine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1309697   PMID:1327965   PMID:2550906   PMID:9344674   PMID:9752724   PMID:10335655   PMID:11997101   PMID:12477932   PMID:15057824   PMID:15489334   PMID:18488190   PMID:19779253  
PMID:19843159   PMID:19913121   PMID:20413852   PMID:20628086   PMID:20877624   PMID:21873635   PMID:22142811   PMID:22419111   PMID:22592081   PMID:22968485   PMID:25666558   PMID:27866983  
PMID:32814053   PMID:33961781   PMID:34800366   PMID:36418320   PMID:38830579  


Genomics

Comparative Map Data
COX7A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381936,150,922 - 36,152,447 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1936,150,922 - 36,152,449 (-)EnsemblGRCh38hg38GRCh38
GRCh371936,641,824 - 36,643,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361941,333,664 - 41,335,611 (-)NCBINCBI36Build 36hg18NCBI36
Build 341941,333,663 - 41,335,611NCBI
Celera1933,355,996 - 33,357,943 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1933,147,296 - 33,149,244 (-)NCBIHuRef
CHM1_11936,643,830 - 36,645,777 (-)NCBICHM1_1
T2T-CHM13v2.01938,696,740 - 38,698,266 (-)NCBIT2T-CHM13v2.0
Cox7a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,883,596 - 29,885,455 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,883,569 - 29,885,503 (+)EnsemblGRCm39 Ensembl
GRCm38730,184,171 - 30,186,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,184,144 - 30,186,078 (+)EnsemblGRCm38mm10GRCm38
MGSCv37730,969,190 - 30,971,049 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,892,931 - 29,894,790 (+)NCBIMGSCv36mm8
Celera724,780,999 - 24,782,841 (+)NCBICelera
Cytogenetic Map7B1NCBI
cM Map717.31NCBI
Cox7a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,549,663 - 94,572,330 (+)NCBIGRCr8
mRatBN7.2185,422,162 - 85,447,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,441,871 - 85,445,151 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx190,858,721 - 90,860,394 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,322,395 - 99,324,068 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0192,616,985 - 92,618,658 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0191,070,593 - 91,096,190 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,071,493 - 91,074,294 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,620,317 - 88,621,868 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,779,961 - 89,783,053 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera179,797,950 - 79,819,656 (+)NCBICelera
Cytogenetic Map1q21NCBI
LOC102008614
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554682,442,819 - 2,445,169 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554682,442,819 - 2,445,169 (+)NCBIChiLan1.0ChiLan1.0
LOC100973061
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22042,152,614 - 42,155,935 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11944,136,168 - 44,137,822 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01933,069,878 - 33,071,835 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,817,074 - 41,819,025 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,817,074 - 41,819,025 (-)Ensemblpanpan1.1panPan2
COX7A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,547,179 - 116,548,917 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,547,282 - 116,548,917 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1115,953,199 - 115,954,926 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,148,601 - 117,150,329 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,148,693 - 117,150,328 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11116,717,978 - 116,719,704 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,338,225 - 116,339,952 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,391,271 - 117,392,998 (+)NCBIUU_Cfam_GSD_1.0
LOC101965810
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,392,153 - 11,393,754 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936922162,286 - 163,839 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936922162,282 - 163,864 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COX7A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,517,229 - 45,520,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,519,225 - 45,520,721 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,921,420 - 40,922,916 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234561
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1631,061,789 - 31,063,722 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660738,862,064 - 8,864,153 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101715151
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,392,028 - 10,393,670 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479410,392,028 - 10,393,728 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COX7A1
9 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
GRCh38/hg38 19q12-13.13(chr19:29661858-38114723)x1 copy number loss See cases [RCV000135879] Chr19:29661858..38114723 [GRCh38]
Chr19:30152765..38605363 [GRCh37]
Chr19:34844605..43297203 [NCBI36]
Chr19:19q12-13.13
pathogenic
GRCh38/hg38 19q12-13.13(chr19:29671324-37902990)x1 copy number loss See cases [RCV000136794] Chr19:29671324..37902990 [GRCh38]
Chr19:30162231..38393630 [GRCh37]
Chr19:34854071..43085470 [NCBI36]
Chr19:19q12-13.13
pathogenic
GRCh37/hg19 19q13.12-13.13(chr19:36475577-38399402)x3 copy number gain See cases [RCV000240597] Chr19:36475577..38399402 [GRCh37]
Chr19:19q13.12-13.13
uncertain significance
GRCh37/hg19 19q13.12(chr19:36606538-36643669)x3 copy number gain See cases [RCV000448457] Chr19:36606538..36643669 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q13.12(chr19:36147111-37249653)x1 copy number loss See cases [RCV000511504] Chr19:36147111..37249653 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19q13.12(chr19:36628463-36758139)x3 copy number gain not provided [RCV000740146] Chr19:36628463..36758139 [GRCh37]
Chr19:19q13.12
benign
GRCh37/hg19 19q13.11-13.12(chr19:35111811-37744992) copy number loss Generalized epilepsy with febrile seizures plus, type 1 [RCV000767768] Chr19:35111811..37744992 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33
pathogenic
GRCh37/hg19 19q13.12(chr19:36570287-36655341)x3 copy number gain not provided [RCV000846132] Chr19:36570287..36655341 [GRCh37]
Chr19:19q13.12
uncertain significance
NC_000019.9:g.(?_33167170)_(36643309_?)dup duplication Hereditary spastic paraplegia 75 [RCV003107659] Chr19:33167170..36643309 [GRCh37]
Chr19:19q13.11-13.12
uncertain significance
GRCh37/hg19 19p13.11-q13.2(chr19:19546923-41313229)x3 copy number gain Specific learning disability [RCV001801194] Chr19:19546923..41313229 [GRCh37]
Chr19:19p13.11-q13.2
pathogenic
NC_000019.9:g.(?_35521725)_(36643309_?)del deletion Brugada syndrome 5 [RCV001910265] Chr19:35521725..36643309 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.52G>T (p.Ala18Ser) single nucleotide variant not specified [RCV004166493] Chr19:36151719 [GRCh38]
Chr19:36642621 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.132G>T (p.Lys44Asn) single nucleotide variant not specified [RCV004223932] Chr19:36151517 [GRCh38]
Chr19:36642419 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.14G>T (p.Arg5Leu) single nucleotide variant not specified [RCV004179941] Chr19:36152394 [GRCh38]
Chr19:36643296 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.161G>A (p.Arg54Gln) single nucleotide variant not specified [RCV004189193] Chr19:36151488 [GRCh38]
Chr19:36642390 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.82G>A (p.Glu28Lys) single nucleotide variant not specified [RCV004154501] Chr19:36151689 [GRCh38]
Chr19:36642591 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q13.12(chr19:36312941-36751702)x3 copy number gain not provided [RCV003485199] Chr19:36312941..36751702 [GRCh37]
Chr19:19q13.12
uncertain significance
Single allele deletion not provided [RCV003448708] Chr19:35225414..37357598 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
GRCh37/hg19 19q11-13.2(chr19:28271146-41508851)x3 copy number gain not specified [RCV003986115] Chr19:28271146..41508851 [GRCh37]
Chr19:19q11-13.2
pathogenic
GRCh37/hg19 19q13.12(chr19:36451071-36752221)x3 copy number gain not specified [RCV003986106] Chr19:36451071..36752221 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.229C>T (p.Pro77Ser) single nucleotide variant not specified [RCV004372282] Chr19:36150993 [GRCh38]
Chr19:36641895 [GRCh37]
Chr19:19q13.12
uncertain significance
NM_001864.4(COX7A1):c.103G>A (p.Glu35Lys) single nucleotide variant not specified [RCV004372281] Chr19:36151546 [GRCh38]
Chr19:36642448 [GRCh37]
Chr19:19q13.12
uncertain significance
GRCh37/hg19 19q13.11-13.12(chr19:35223021-36895699)x1 copy number loss not provided [RCV004577477] Chr19:35223021..36895699 [GRCh37]
Chr19:19q13.11-13.12
pathogenic
NM_001864.4(COX7A1):c.99C>A (p.Phe33Leu) single nucleotide variant not specified [RCV004610888] Chr19:36151672 [GRCh38]
Chr19:36642574 [GRCh37]
Chr19:19q13.12
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1418
Count of miRNA genes:567
Interacting mature miRNAs:640
Transcripts:ENST00000292907, ENST00000437291, ENST00000481297, ENST00000589154
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300034BP50_HBlood pressure QTL 50 (human)2.10.00094Blood pressuresystolic191108946337089463Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
597402970GWAS1499044_Hneuritic plaque measurement QTL GWAS1499044 (human)0.0000006neuritic plaque measurement193615198236151983Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human

Markers in Region
RH93348  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371936,641,827 - 36,642,386UniSTSGRCh37
Celera1933,355,999 - 33,356,558UniSTS
Cytogenetic Map19q13.1UniSTS
HuRef1933,147,299 - 33,147,858UniSTS
GeneMap99-GB4 RH Map19216.04UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2391 2788 2239 4920 1714 2277 4 621 1598 461 2239 6899 6123 28 3700 1 827 1717 1549 174 1

Sequence


Ensembl Acc Id: ENST00000292907   ⟹   ENSP00000292907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1936,150,922 - 36,152,447 (-)Ensembl
Ensembl Acc Id: ENST00000437291   ⟹   ENSP00000475885
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1936,150,922 - 36,152,025 (-)Ensembl
Ensembl Acc Id: ENST00000481297
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1936,150,922 - 36,152,449 (-)Ensembl
Ensembl Acc Id: ENST00000589154   ⟹   ENSP00000468063
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1936,151,013 - 36,152,436 (-)Ensembl
RefSeq Acc Id: NM_001864   ⟹   NP_001855
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381936,150,922 - 36,152,447 (-)NCBI
GRCh371936,641,824 - 36,643,771 (-)ENTREZGENE
Build 361941,333,664 - 41,335,611 (-)NCBI Archive
HuRef1933,147,296 - 33,149,244 (-)ENTREZGENE
CHM1_11936,643,830 - 36,645,777 (-)NCBI
T2T-CHM13v2.01938,696,740 - 38,698,266 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001855   ⟸   NM_001864
- Peptide Label: precursor
- UniProtKB: P24310 (UniProtKB/Swiss-Prot),   H6SG12 (UniProtKB/TrEMBL),   Q6FGI7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000292907   ⟸   ENST00000292907
Ensembl Acc Id: ENSP00000468063   ⟸   ENST00000589154
Ensembl Acc Id: ENSP00000475885   ⟸   ENST00000437291

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P24310-F1-model_v2 AlphaFold P24310 1-79 view protein structure

Promoters
RGD ID:7239651
Promoter ID:EPDNEW_H25572
Type:initiation region
Name:COX7A1_1
Description:cytochrome c oxidase subunit 7A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381936,152,447 - 36,152,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:2287 AgrOrtholog
COSMIC COX7A1 COSMIC
Ensembl Genes ENSG00000161281 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000292907 ENTREZGENE
  ENST00000292907.8 UniProtKB/Swiss-Prot
  ENST00000437291.6 UniProtKB/TrEMBL
  ENST00000589154.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.91.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000161281 GTEx
HGNC ID HGNC:2287 ENTREZGENE
Human Proteome Map COX7A1 Human Proteome Map
InterPro COX7a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxidase_su7a_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cytc_oxidase_su7a_met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:1346 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 1346 ENTREZGENE
OMIM 123995 OMIM
PANTHER CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10510 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COX7a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26805 PharmGKB
Superfamily-SCOP SSF81419 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CX7A1_HUMAN UniProtKB/Swiss-Prot
  H6SG12 ENTREZGENE, UniProtKB/TrEMBL
  K7ER11_HUMAN UniProtKB/TrEMBL
  P24310 ENTREZGENE
  Q6FGI7 ENTREZGENE, UniProtKB/TrEMBL
  U3KQH8_HUMAN UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-16 COX7A1  cytochrome c oxidase subunit 7A1  COX7A1  cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)  Symbol and/or name change 5135510 APPROVED