KRT8 (keratin 8) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: KRT8 (keratin 8) Homo sapiens
Analyze
Symbol: KRT8
Name: keratin 8
RGD ID: 735536
HGNC Page HGNC
Description: Exhibits scaffold protein binding activity. Predicted to be involved in cornification. Localizes to cytoplasm and intermediate filament. Implicated in liver cirrhosis. Biomarker of liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CARD2; CK-8; CK8; CYK8; cytokeratin 8; cytokeratin-8; K2C8; K8; keratin 8, type II; keratin, type II cytoskeletal 8; keratin-8; KO; type-II keratin Kb8
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: KRT8P1   KRT8P10   KRT8P11   KRT8P12   KRT8P13   KRT8P14   KRT8P15   KRT8P16   KRT8P17   KRT8P18   KRT8P19   KRT8P2   KRT8P20   KRT8P21   KRT8P22   KRT8P23   KRT8P24   KRT8P25   KRT8P26   KRT8P27   KRT8P28   KRT8P29   KRT8P3   KRT8P30   KRT8P31   KRT8P32   KRT8P33   KRT8P34   KRT8P35   KRT8P36   KRT8P37   KRT8P38   KRT8P39   KRT8P4   KRT8P40   KRT8P41   KRT8P42   KRT8P43   KRT8P44   KRT8P45   KRT8P46   KRT8P47   KRT8P48   KRT8P49   KRT8P5   KRT8P50   KRT8P51   KRT8P52   KRT8P6   KRT8P7   KRT8P8   KRT8P9   KRT90P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,897,187 - 52,949,954 (-)EnsemblGRCh38hg38GRCh38
GRCh381252,897,191 - 52,949,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371253,290,975 - 53,343,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,577,238 - 51,585,127 (-)NCBINCBI36hg18NCBI36
Build 341251,577,241 - 51,585,089NCBI
Celera1252,937,521 - 52,945,403 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBIHuRef
CHM1_11253,257,746 - 53,310,407 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (ISO)
acrolein  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
all-trans-4-oxoretinoic acid  (EXP)
all-trans-4-oxoretinol  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
amiodarone  (ISO)
arachidonic acid  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-carotene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (EXP)
Butylparaben  (EXP)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
calciol  (ISO)
captan  (ISO)
carbon nanotube  (EXP,ISO)
carmustine  (EXP)
chlordecone  (ISO)
chloroform  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciprofibrate  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
cumene  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
cytarabine  (EXP)
daunorubicin  (ISO)
DDT  (EXP)
dexamethasone  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
elemental selenium  (EXP)
entinostat  (EXP)
ethanol  (EXP)
fenofibrate  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
flavone  (EXP)
flutamide  (ISO)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (EXP)
fumonisin B1  (ISO)
furan  (ISO)
gemcitabine  (EXP)
genistein  (EXP,ISO)
griseofulvin  (ISO)
hexadecanoic acid  (EXP)
hydrazine  (ISO)
iron(III) nitrilotriacetate  (EXP)
isoflavones  (ISO)
L-ethionine  (ISO)
L-methionine  (ISO)
medroxyprogesterone acetate  (EXP)
megestrol acetate  (EXP)
menadione  (EXP)
mercury dibromide  (EXP)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methylmercury chloride  (EXP)
methylparaben  (EXP)
microcystin-LR  (EXP,ISO)
Monobutylphthalate  (ISO)
morphine  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-acetyl-L-cysteine  (EXP)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
nystatin  (ISO)
omeprazole  (ISO)
orphenadrine  (ISO)
p-chloromercuribenzoic acid  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorododecanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosgene  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
quercetin  (EXP,ISO)
rac-1,2-dichloropropane  (ISO)
rotenone  (ISO)
SB 203580  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
SU6656  (EXP)
sulforaphane  (EXP)
sunitinib  (EXP)
T-2 toxin  (ISO)
tamoxifen  (ISO)
temozolomide  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thapsigargin  (EXP)
theophylline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (EXP)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1371500   PMID:1374067   PMID:1690513   PMID:1691124   PMID:1692965   PMID:1705144   PMID:1711732   PMID:2434381   PMID:2456993   PMID:2459839   PMID:2467436   PMID:2471065  
PMID:2482017   PMID:6186379   PMID:8037842   PMID:8125298   PMID:8895530   PMID:9054461   PMID:9150948   PMID:9211903   PMID:9409741   PMID:9459484   PMID:9560222   PMID:9630597  
PMID:9988531   PMID:10809736   PMID:10852826   PMID:10954706   PMID:11076863   PMID:11581269   PMID:11684708   PMID:11781324   PMID:11788583   PMID:11790298   PMID:11923318   PMID:12168793  
PMID:12218095   PMID:12235123   PMID:12366696   PMID:12367790   PMID:12388748   PMID:12429849   PMID:12474161   PMID:12477932   PMID:12577067   PMID:12724528   PMID:12868678   PMID:14556659  
PMID:14568682   PMID:14744259   PMID:14756564   PMID:15090596   PMID:15194421   PMID:15235035   PMID:15248378   PMID:15252834   PMID:15314064   PMID:15319370   PMID:15489334   PMID:15489336  
PMID:15529338   PMID:15671067   PMID:15731013   PMID:15737616   PMID:15822942   PMID:15838910   PMID:15846844   PMID:15952740   PMID:15972820   PMID:16000376   PMID:16083285   PMID:16143128  
PMID:16169070   PMID:16212417   PMID:16327287   PMID:16341674   PMID:16344560   PMID:16381901   PMID:16565220   PMID:16608857   PMID:16831889   PMID:16892178   PMID:16911694   PMID:16944923  
PMID:16964243   PMID:17034788   PMID:17039343   PMID:17081983   PMID:17126832   PMID:17213200   PMID:17353931   PMID:17373842   PMID:17509943   PMID:17954264   PMID:18236071   PMID:18343496  
PMID:18353540   PMID:18432282   PMID:18497550   PMID:18577580   PMID:18725232   PMID:18941637   PMID:18953437   PMID:19032382   PMID:19115206   PMID:19188445   PMID:19190970   PMID:19199708  
PMID:19204726   PMID:19246484   PMID:19282868   PMID:19380743   PMID:19419944   PMID:19585610   PMID:19615732   PMID:19738201   PMID:19755983   PMID:19845941   PMID:20098747   PMID:20109457  
PMID:20348541   PMID:20398190   PMID:20508642   PMID:20530580   PMID:20538000   PMID:20587546   PMID:20618440   PMID:20659422   PMID:20729549   PMID:20808760   PMID:20817646   PMID:20926822  
PMID:20936779   PMID:21149639   PMID:21548936   PMID:21565611   PMID:21630459   PMID:21654808   PMID:21705376   PMID:21743057   PMID:21900206   PMID:21988832   PMID:22038833   PMID:22114688  
PMID:22119785   PMID:22270320   PMID:22304920   PMID:22344252   PMID:22354665   PMID:22379894   PMID:22412904   PMID:22419260   PMID:22458338   PMID:22623428   PMID:22677743   PMID:22853896  
PMID:22915798   PMID:22939629   PMID:23078008   PMID:23164509   PMID:23327593   PMID:23341946   PMID:23358244   PMID:23398456   PMID:23438482   PMID:23449973   PMID:23533145   PMID:23801880  
PMID:23940030   PMID:23990477   PMID:24003221   PMID:24115814   PMID:24166186   PMID:24183726   PMID:24327340   PMID:24337577   PMID:24338534   PMID:24457600   PMID:24915158   PMID:24930437  
PMID:25113562   PMID:25120060   PMID:25416956   PMID:25724181   PMID:25963979   PMID:26167880   PMID:26209609   PMID:26277397   PMID:26280121   PMID:26286715   PMID:26462837   PMID:26485645  
PMID:26496610   PMID:26522727   PMID:26732321   PMID:26769854   PMID:26823019   PMID:26847082   PMID:26876307   PMID:26910849   PMID:26911253   PMID:27248496   PMID:27304995   PMID:27545878  
PMID:27578003   PMID:27586056   PMID:27591049   PMID:27609421   PMID:27870250   PMID:27880917   PMID:28045574   PMID:28117675   PMID:28378594   PMID:28443643   PMID:28468590   PMID:28515276  
PMID:28652657   PMID:28718761   PMID:28977666   PMID:29401296   PMID:29443941   PMID:29507755   PMID:29802200   PMID:29845934   PMID:29859926   PMID:29884220   PMID:29892012   PMID:29911972  
PMID:30021884   PMID:30575818   PMID:30634629   PMID:30725116   PMID:30809309   PMID:30811493   PMID:31199680   PMID:31253590   PMID:31343991   PMID:31391242   PMID:31462707   PMID:31515488  
PMID:31515557   PMID:31741433   PMID:32296183   PMID:32678092   PMID:32780723   PMID:32786267  


Genomics

Comparative Map Data
KRT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,897,187 - 52,949,954 (-)EnsemblGRCh38hg38GRCh38
GRCh381252,897,191 - 52,949,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371253,290,975 - 53,343,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,577,238 - 51,585,127 (-)NCBINCBI36hg18NCBI36
Build 341251,577,241 - 51,585,089NCBI
Celera1252,937,521 - 52,945,403 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBIHuRef
CHM1_11253,257,746 - 53,310,407 (-)NCBICHM1_1
Krt8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,905,146 - 101,912,777 (-)NCBIGRCm39mm39
GRCm39 Ensembl15101,905,133 - 101,912,917 (-)Ensembl
GRCm3815101,996,711 - 102,004,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,996,698 - 102,004,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715101,827,142 - 101,834,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615101,824,745 - 101,832,317 (-)NCBImm8
Celera15104,151,508 - 104,159,109 (-)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.2NCBI
Krt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27133,124,203 - 133,131,656 (-)NCBI
Rnor_6.0 Ensembl7143,596,511 - 143,603,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07143,596,511 - 143,603,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07141,393,004 - 141,400,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,713,902 - 140,721,199 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,790,339 - 140,797,636 (-)NCBI
Celera7129,561,335 - 129,568,866 (-)NCBICelera
Cytogenetic Map7q36NCBI
Krt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955458178,954 - 190,310 (-)NCBIChiLan1.0ChiLan1.0
KRT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11236,634,582 - 36,642,564 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,634,582 - 36,642,564 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01235,855,367 - 35,863,248 (+)NCBIMhudiblu_PPA_v0panPan3
KRT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,221,608 - 2,229,343 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,022,937 - 44,030,605 (-)NCBI
ROS_Cfam_1.0272,222,635 - 2,230,328 (+)NCBI
UMICH_Zoey_3.1272,239,283 - 2,246,949 (+)NCBI
UNSW_CanFamBas_1.0272,225,535 - 2,233,175 (+)NCBI
UU_Cfam_GSD_1.02744,422,008 - 44,429,675 (-)NCBI
Krt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,910,080 - 62,917,785 (+)NCBI
SpeTri2.0NW_00493651210,247,049 - 10,254,748 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,170,354 - 18,180,404 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,172,423 - 18,180,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,663,339 - 18,671,193 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,027,879 - 49,051,753 (-)NCBI
Krt8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624904970,136 - 978,211 (-)NCBI

Position Markers
D12S765  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371253,291,129 - 53,291,563UniSTSGRCh37
Build 361251,577,396 - 51,577,830RGDNCBI36
Celera1252,937,679 - 52,938,113RGD
Cytogenetic Map12q13UniSTS
HuRef1250,334,827 - 50,335,261UniSTS
GDB:376877  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371253,295,118 - 53,295,467UniSTSGRCh37
Build 361251,581,385 - 51,581,734RGDNCBI36
Celera1252,941,668 - 52,942,017RGD
Cytogenetic Map12q13UniSTS
HuRef1250,338,816 - 50,339,165UniSTS
D17S1697  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q13UniSTS
RH79790  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q13UniSTS
RH47175  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q13UniSTS
GeneMap99-GB4 RH Map12227.97UniSTS
NCBI RH Map12442.2UniSTS
GDB:277179  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q13UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5281
Count of miRNA genes:1061
Interacting mature miRNAs:1343
Transcripts:ENST00000293308, ENST00000546542, ENST00000546583, ENST00000546826, ENST00000546897, ENST00000546900, ENST00000546921, ENST00000547031, ENST00000547176, ENST00000547413, ENST00000548998, ENST00000549176, ENST00000549198, ENST00000550170, ENST00000551318, ENST00000552150, ENST00000552551, ENST00000552877
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 229 33 24 9 28 1 4 26 143 116 1 2
Medium 2119 1463 1636 590 346 433 1305 1222 324 388 692 1474 166 455 660 2
Low 88 982 49 9 547 3 2342 260 1508 3 612 16 5 748 1429 1 2
Below cutoff 2 540 7 1 901 1 707 704 1876 2 8 5 699

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_008402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001256282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001256293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_045962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI150751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC075839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE300986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM854215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX417476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX166336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA051933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA825311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M34225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M34482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U76549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X12882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X98614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z36777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000293308   ⟹   ENSP00000293308
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,194 - 52,906,618 (-)Ensembl
RefSeq Acc Id: ENST00000546542   ⟹   ENSP00000450228
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,904,676 - 52,907,060 (-)Ensembl
RefSeq Acc Id: ENST00000546583
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,208 - 52,905,052 (-)Ensembl
RefSeq Acc Id: ENST00000546826   ⟹   ENSP00000447881
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,899,935 - 52,949,882 (-)Ensembl
RefSeq Acc Id: ENST00000546897   ⟹   ENSP00000447402
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,281 - 52,949,824 (-)Ensembl
RefSeq Acc Id: ENST00000546900   ⟹   ENSP00000450340
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,900,588 - 52,903,648 (-)Ensembl
RefSeq Acc Id: ENST00000546921
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,949,216 - 52,949,954 (-)Ensembl
RefSeq Acc Id: ENST00000547031
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,898,469 - 52,901,867 (-)Ensembl
RefSeq Acc Id: ENST00000547176   ⟹   ENSP00000449010
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,899,996 - 52,901,947 (-)Ensembl
RefSeq Acc Id: ENST00000548998   ⟹   ENSP00000447040
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,900,008 - 52,949,776 (-)Ensembl
RefSeq Acc Id: ENST00000549176
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,899,794 - 52,902,204 (-)Ensembl
RefSeq Acc Id: ENST00000549198
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,948,484 - 52,949,831 (-)Ensembl
RefSeq Acc Id: ENST00000550170
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,216 - 52,905,044 (-)Ensembl
RefSeq Acc Id: ENST00000551318
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,948,651 - 52,949,920 (-)Ensembl
RefSeq Acc Id: ENST00000552150   ⟹   ENSP00000449404
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,297 - 52,926,469 (-)Ensembl
RefSeq Acc Id: ENST00000552551   ⟹   ENSP00000447566
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,897,187 - 52,949,842 (-)Ensembl
RefSeq Acc Id: ENST00000619952   ⟹   ENSP00000489174
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1252,946,614 - 52,949,874 (-)Ensembl
RefSeq Acc Id: NM_001256282   ⟹   NP_001243211
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,897,191 - 52,926,469 (-)NCBI
GRCh371253,290,971 - 53,343,650 (-)NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBI
CHM1_11253,257,746 - 53,287,034 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001256293   ⟹   NP_001243222
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,897,191 - 52,949,860 (-)NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBI
CHM1_11253,257,746 - 53,310,407 (-)NCBI
Sequence:
RefSeq Acc Id: NM_002273   ⟹   NP_002264
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,897,191 - 52,905,076 (-)NCBI
GRCh371253,290,971 - 53,343,650 (-)NCBI
Build 361251,577,238 - 51,585,127 (-)NCBI Archive
HuRef1250,334,669 - 50,387,466 (-)NCBI
CHM1_11253,257,746 - 53,265,652 (-)NCBI
Sequence:
RefSeq Acc Id: NR_045962
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,897,191 - 52,949,860 (-)NCBI
GRCh371253,290,971 - 53,343,650 (-)NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBI
CHM1_11253,257,746 - 53,310,407 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002264   ⟸   NM_002273
- Peptide Label: isoform 2
- UniProtKB: P05787 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001243222   ⟸   NM_001256293
- Peptide Label: isoform 2
- UniProtKB: P05787 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001243211   ⟸   NM_001256282
- Peptide Label: isoform 1
- UniProtKB: Q7L4M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000293308   ⟸   ENST00000293308
RefSeq Acc Id: ENSP00000450228   ⟸   ENST00000546542
RefSeq Acc Id: ENSP00000450340   ⟸   ENST00000546900
RefSeq Acc Id: ENSP00000447881   ⟸   ENST00000546826
RefSeq Acc Id: ENSP00000447402   ⟸   ENST00000546897
RefSeq Acc Id: ENSP00000449010   ⟸   ENST00000547176
RefSeq Acc Id: ENSP00000447040   ⟸   ENST00000548998
RefSeq Acc Id: ENSP00000489174   ⟸   ENST00000619952
RefSeq Acc Id: ENSP00000447566   ⟸   ENST00000552551
RefSeq Acc Id: ENSP00000449404   ⟸   ENST00000552150
Protein Domains
IF rod   Keratin_2_head

Promoters
RGD ID:6810327
Promoter ID:HG_ACW:17071
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid,   NB4
Transcripts:KRT8.NAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361251,583,639 - 51,584,139 (-)MPROMDB
RGD ID:6790185
Promoter ID:HG_KWN:15718
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562
Transcripts:NM_002273,   UC009ZMJ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361251,584,766 - 51,585,266 (-)MPROMDB
RGD ID:7224049
Promoter ID:EPDNEW_H17770
Type:initiation region
Name:KRT8_1
Description:keratin 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,926,469 - 52,926,529EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002273.4(KRT8):c.184G>T (p.Gly62Cys) single nucleotide variant Cirrhosis, cryptogenic [RCV000015735]|Cirrhosis, noncryptogenic, susceptibility to [RCV000015736]|not provided [RCV000056938] Chr12:52904798 [GRCh38]
Chr12:53298582 [GRCh37]
Chr12:12q13.13
pathogenic|risk factor|not provided
NM_002273.4(KRT8):c.160T>C (p.Tyr54His) single nucleotide variant Cirrhosis, cryptogenic [RCV000015737]|Susceptibility to hepatitis C virus [RCV000988859]|not provided [RCV000056936] Chr12:52904822 [GRCh38]
Chr12:53298606 [GRCh37]
Chr12:12q13.13
pathogenic|risk factor|uncertain significance|not provided
NM_002273.4(KRT8):c.1033G>T (p.Ala345Ser) single nucleotide variant Susceptibility to hepatitis C virus [RCV000049579] Chr12:52898848 [GRCh38]
Chr12:53292632 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1340C>T (p.Ala447Val) single nucleotide variant Susceptibility to hepatitis C virus [RCV000049580] Chr12:52897540 [GRCh38]
Chr12:53291324 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1412G>A (p.Gly471Glu) single nucleotide variant Susceptibility to hepatitis C virus [RCV000049581] Chr12:52897468 [GRCh38]
Chr12:53291252 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.*31C>T single nucleotide variant not provided [RCV000056922] Chr12:52897397 [GRCh38]
Chr12:53291181 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.*38G>A single nucleotide variant not provided [RCV000056923] Chr12:52897390 [GRCh38]
Chr12:53291174 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.*8C>T single nucleotide variant not provided [RCV000056924] Chr12:52897420 [GRCh38]
Chr12:53291204 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1021C>T (p.Arg341Cys) single nucleotide variant not provided [RCV000056925] Chr12:52898860 [GRCh38]
Chr12:53292644 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1022G>A (p.Arg341His) single nucleotide variant not provided [RCV000056926] Chr12:52898859 [GRCh38]
Chr12:53292643 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1128G>A (p.Glu376=) single nucleotide variant not provided [RCV000056927] Chr12:52898753 [GRCh38]
Chr12:53292537 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1138G>A (p.Val380Ile) single nucleotide variant not provided [RCV000056928] Chr12:52898743 [GRCh38]
Chr12:53292527 [GRCh37]
Chr12:12q13.13
likely benign|not provided
NM_002273.4(KRT8):c.1202+46A>T single nucleotide variant not provided [RCV000056929] Chr12:52898633 [GRCh38]
Chr12:53292417 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1261+11del deletion not provided [RCV000056930] Chr12:52898450 [GRCh38]
Chr12:53292234 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1261+20G>A single nucleotide variant not provided [RCV000056931] Chr12:52898441 [GRCh38]
Chr12:53292225 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1300G>A (p.Gly434Ser) single nucleotide variant not provided [RCV000056932] Chr12:52897580 [GRCh38]
Chr12:53291364 [GRCh37]
Chr12:12q13.13
benign|not provided
NM_002273.4(KRT8):c.1360C>T (p.Arg454Cys) single nucleotide variant not provided [RCV000056933] Chr12:52897520 [GRCh38]
Chr12:53291304 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.1392G>T (p.Lys464Asn) single nucleotide variant not provided [RCV000056934] Chr12:52897488 [GRCh38]
Chr12:53291272 [GRCh37]
Chr12:12q13.13
uncertain significance|not provided
NM_002273.4(KRT8):c.158G>T (p.Gly53Val) single nucleotide variant not provided [RCV000056935] Chr12:52904824 [GRCh38]
Chr12:53298608 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.164G>C (p.Gly55Ala) single nucleotide variant not provided [RCV000056937] Chr12:52904818 [GRCh38]
Chr12:53298602 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.187A>G (p.Ile63Val) single nucleotide variant Inflammatory bowel disease [RCV001258260]|Susceptibility to hepatitis C virus [RCV000988858]|not provided [RCV000056939]|not specified [RCV000612895] Chr12:52904795 [GRCh38]
Chr12:53298579 [GRCh37]
Chr12:12q13.13
benign|likely benign|not provided
NM_002273.4(KRT8):c.216G>A (p.Leu72=) single nucleotide variant not provided [RCV000056940] Chr12:52904766 [GRCh38]
Chr12:53298550 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.681A>G (p.Leu227=) single nucleotide variant not provided [RCV000056941] Chr12:52900597 [GRCh38]
Chr12:53294381 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.77C>G (p.Thr26Arg) single nucleotide variant not provided [RCV000056942] Chr12:52904905 [GRCh38]
Chr12:53298689 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.4(KRT8):c.955G>T (p.Ala319Ser) single nucleotide variant not provided [RCV000056943] Chr12:52899801 [GRCh38]
Chr12:53293585 [GRCh37]
Chr12:12q13.13
not provided
NM_002273.3(KRT8):c.574G>A (p.Glu192Lys) single nucleotide variant Malignant melanoma [RCV000062538] Chr12:52901179 [GRCh38]
Chr12:53294963 [GRCh37]
Chr12:51581230 [NCBI36]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.282C>T (p.Tyr94=) single nucleotide variant Susceptibility to hepatitis C virus [RCV000049577] Chr12:52949455 [GRCh38]
Chr12:53343239 [GRCh37]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.134G>C (p.Arg45Pro) single nucleotide variant Susceptibility to hepatitis C virus [RCV000049578] Chr12:52949307 [GRCh38]
Chr12:53343091 [GRCh37]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.-15C>T single nucleotide variant not provided [RCV000056430] Chr12:52949159 [GRCh38]
Chr12:53342943 [GRCh37]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.193_216del (p.Thr65_Ala72del) deletion not provided [RCV000056433] Chr12:52949366..52949389 [GRCh38]
Chr12:53343150..53343173 [GRCh37]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.307A>G (p.Thr103Ala) single nucleotide variant not provided [RCV000056434] Chr12:52949480 [GRCh38]
Chr12:53343264 [GRCh37]
Chr12:12q13.13
not provided
NM_000224.3(KRT18):c.383A>T (p.His128Leu) single nucleotide variant Cirrhosis, cryptogenic [RCV000015686]|Cirrhosis, noncryptogenic, susceptibility to [RCV000015687]|not provided [RCV000056435] Chr12:52949556 [GRCh38]
Chr12:53343340 [GRCh37]
Chr12:12q13.13
pathogenic|risk factor|not provided
GRCh38/hg38 12q13.13(chr12:52851850-53558824)x3 copy number gain See cases [RCV000138030] Chr12:52851850..53558824 [GRCh38]
Chr12:53245634..53952608 [GRCh37]
Chr12:51531901..52238875 [NCBI36]
Chr12:12q13.13
likely pathogenic
GRCh38/hg38 12q13.13(chr12:52748391-52950618)x3 copy number gain See cases [RCV000138642] Chr12:52748391..52950618 [GRCh38]
Chr12:53142175..53344402 [GRCh37]
Chr12:51428442..51630669 [NCBI36]
Chr12:12q13.13
likely benign
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q13.12-13.13(chr12:50122359-53248460)x1 copy number loss See cases [RCV000142033] Chr12:50122359..53248460 [GRCh38]
Chr12:50516142..53642244 [GRCh37]
Chr12:48802409..51928511 [NCBI36]
Chr12:12q13.12-13.13
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_002273.4(KRT8):c.1438G>A (p.Val480Ile) single nucleotide variant not provided [RCV000885225] Chr12:52897442 [GRCh38]
Chr12:53291226 [GRCh37]
Chr12:12q13.13
benign
NM_002273.4(KRT8):c.87C>T (p.Pro29=) single nucleotide variant not provided [RCV000884588] Chr12:52904895 [GRCh38]
Chr12:53298679 [GRCh37]
Chr12:12q13.13
likely benign
NM_002273.4(KRT8):c.1261+9C>T single nucleotide variant not provided [RCV000969626] Chr12:52898452 [GRCh38]
Chr12:53292236 [GRCh37]
Chr12:12q13.13
benign
NM_002273.4(KRT8):c.999C>T (p.Ala333=) single nucleotide variant not provided [RCV000947459] Chr12:52898882 [GRCh38]
Chr12:53292666 [GRCh37]
Chr12:12q13.13
benign
NM_002273.4(KRT8):c.1305C>T (p.Leu435=) single nucleotide variant not provided [RCV000944050] Chr12:52897575 [GRCh38]
Chr12:53291359 [GRCh37]
Chr12:12q13.13
likely benign
NM_000224.3(KRT18):c.206G>C (p.Gly69Ala) single nucleotide variant Familial cirrhosis [RCV001331079] Chr12:52949379 [GRCh38]
Chr12:53343163 [GRCh37]
Chr12:12q13.13
uncertain significance
NM_002273.4(KRT8):c.1202+1G>A single nucleotide variant Familial cirrhosis [RCV001334028] Chr12:52898678 [GRCh38]
Chr12:53292462 [GRCh37]
Chr12:12q13.13
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6446 AgrOrtholog
COSMIC KRT8 COSMIC
Ensembl Genes ENSG00000170421 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000293308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000447040 UniProtKB/TrEMBL
  ENSP00000447402 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000447566 UniProtKB/Swiss-Prot
  ENSP00000447881 UniProtKB/TrEMBL
  ENSP00000449010 UniProtKB/TrEMBL
  ENSP00000449404 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000450228 UniProtKB/TrEMBL
  ENSP00000450340 UniProtKB/TrEMBL
  ENSP00000489174 UniProtKB/TrEMBL
Ensembl Transcript ENST00000293308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000546542 UniProtKB/TrEMBL
  ENST00000546826 UniProtKB/TrEMBL
  ENST00000546897 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000546900 UniProtKB/TrEMBL
  ENST00000547176 UniProtKB/TrEMBL
  ENST00000548998 UniProtKB/TrEMBL
  ENST00000552150 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000552551 UniProtKB/Swiss-Prot
  ENST00000619952 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000170421 GTEx
HGNC ID HGNC:6446 ENTREZGENE
Human Proteome Map KRT8 Human Proteome Map
InterPro IF_conserved UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom_coil1B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3856 UniProtKB/Swiss-Prot
NCBI Gene 3856 ENTREZGENE
OMIM 148060 OMIM
  215600 OMIM
Pfam Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30234 PharmGKB
PRINTS TYPE2KERATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RQU6_HUMAN UniProtKB/TrEMBL
  F8VP67_HUMAN UniProtKB/TrEMBL
  F8VQY3_HUMAN UniProtKB/TrEMBL
  F8VUG2_HUMAN UniProtKB/TrEMBL
  F8W1U3_HUMAN UniProtKB/TrEMBL
  H0YIB2_HUMAN UniProtKB/TrEMBL
  K2C8_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q7L4M3 ENTREZGENE, UniProtKB/TrEMBL
  Q969I0_HUMAN UniProtKB/TrEMBL
UniProt Secondary A8K4H3 UniProtKB/Swiss-Prot
  B0AZN5 UniProtKB/Swiss-Prot
  F8VXB4 UniProtKB/Swiss-Prot
  Q14099 UniProtKB/Swiss-Prot
  Q14716 UniProtKB/Swiss-Prot
  Q14717 UniProtKB/Swiss-Prot
  Q53GJ0 UniProtKB/Swiss-Prot
  Q6DHW5 UniProtKB/Swiss-Prot
  Q6GMY0 UniProtKB/Swiss-Prot
  Q6P4C7 UniProtKB/Swiss-Prot
  Q96J60 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 KRT8  keratin 8    keratin 8, type II  Symbol and/or name change 5135510 APPROVED
2015-01-27 KRT8  keratin 8, type II    keratin 8  Symbol and/or name change 5135510 APPROVED