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Gene: KRT8 (keratin 8) Homo sapiens
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Symbol: KRT8
Name: keratin 8
Description: Exhibits scaffold protein binding activity. Predicted to be involved in cornification. Localizes to the cytoplasm and intermediate filament. Implicated in liver cirrhosis. Biomarker of liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CARD2; CK-8; CK8; CYK8; cytokeratin 8; cytokeratin-8; K2C8; K8; keratin 8, type II; keratin, type II cytoskeletal 8; keratin-8; KO; type-II keratin Kb8
Orthologs:
Mus musculus (house mouse) : Krt8 (keratin 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Krt8 (keratin 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Krt8 (keratin 8)
Pan paniscus (bonobo/pygmy chimpanzee) : KRT8 (keratin 8)
Canis lupus familiaris (dog) : KRT8 (keratin 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Krt8 (keratin 8)
Sus scrofa (pig) : KRT8 (keratin 8)
more info ...
Related Pseudogenes: KRT8P1   KRT8P10   KRT8P11   KRT8P12   KRT8P13   KRT8P14   KRT8P15   KRT8P16   KRT8P17   KRT8P18   KRT8P19   KRT8P2   KRT8P20   KRT8P21   KRT8P22   KRT8P23   KRT8P24   KRT8P25   KRT8P26   KRT8P27   KRT8P28   KRT8P29   KRT8P3   KRT8P30   KRT8P31   KRT8P32   KRT8P33   KRT8P34   KRT8P35   KRT8P36   KRT8P37   KRT8P38   KRT8P39   KRT8P4   KRT8P40   KRT8P41   KRT8P42   KRT8P43   KRT8P44   KRT8P45   KRT8P46   KRT8P47   KRT8P48   KRT8P49   KRT8P5   KRT8P50   KRT8P51   KRT8P6   KRT8P7   KRT8P8   KRT8P9   KRT90P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,897,191 - 52,949,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371253,290,971 - 53,343,650 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,577,238 - 51,585,127 (-)NCBINCBI36hg18NCBI36
Build 341251,577,241 - 51,585,089NCBI
Celera1252,937,521 - 52,945,403 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBIHuRef
CHM1_11253,257,746 - 53,310,407 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KRT8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735536
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.