KRT8 (keratin 8) - Rat Genome Database
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Gene: KRT8 (keratin 8) Sus scrofa
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Symbol: KRT8
Name: keratin 8
RGD ID: 14073293
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN cell differentiation involved in embryonic placenta development (ortholog); extrinsic apoptotic signaling pathway (ortholog); hepatocyte apoptotic process (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); adenocarcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN apicolateral plasma membrane (ortholog); cell periphery (ortholog); cell-cell junction (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: keratin, type II cytoskeletal 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,170,354 - 18,180,404 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,172,423 - 18,180,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,663,339 - 18,671,193 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:18432282   PMID:23196707  


Genomics

Comparative Map Data
KRT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,170,354 - 18,180,404 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,172,423 - 18,180,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,663,339 - 18,671,193 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,897,187 - 52,949,954 (-)EnsemblGRCh38hg38GRCh38
GRCh381252,897,191 - 52,949,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371253,290,975 - 53,343,644 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371253,290,971 - 53,343,650 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,577,238 - 51,585,127 (-)NCBINCBI36hg18NCBI36
Build 341251,577,241 - 51,585,089NCBI
Celera1252,937,521 - 52,945,403 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,334,669 - 50,387,466 (-)NCBIHuRef
CHM1_11253,257,746 - 53,310,407 (-)NCBICHM1_1
Krt8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,905,146 - 101,912,777 (-)NCBIGRCm39mm39
GRCm3815101,996,711 - 102,004,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,996,698 - 102,004,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715101,827,142 - 101,834,773 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615101,824,745 - 101,832,317 (-)NCBImm8
Celera15104,151,508 - 104,159,109 (-)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.2NCBI
Krt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27133,124,203 - 133,131,656 (-)NCBI
Rnor_6.0 Ensembl7143,596,511 - 143,603,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07143,596,511 - 143,603,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07141,393,004 - 141,400,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,713,902 - 140,721,199 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,790,339 - 140,797,636 (-)NCBI
Celera7129,561,335 - 129,568,866 (-)NCBICelera
Cytogenetic Map7q36NCBI
Krt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955458178,954 - 190,310 (-)NCBIChiLan1.0ChiLan1.0
KRT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11236,634,582 - 36,642,564 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,634,582 - 36,642,564 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01235,855,367 - 35,863,248 (+)NCBIMhudiblu_PPA_v0panPan3
KRT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,221,608 - 2,229,343 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Krt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493651210,247,049 - 10,254,748 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,027,879 - 49,051,753 (-)NCBI
Krt8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624904970,136 - 978,211 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 3 3 2 2
Low 2 2 3 1 1 1 1
Below cutoff 2 1 5 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000042524   ⟹   ENSSSCP00000040087
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl518,172,430 - 18,180,404 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000048358   ⟹   ENSSSCP00000046493
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl518,170,354 - 18,180,283 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000054375   ⟹   ENSSSCP00000049177
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl518,172,600 - 18,180,215 (-)Ensembl
RefSeq Acc Id: NM_001159615   ⟹   NP_001153087
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1518,172,423 - 18,180,277 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001153087 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001153087   ⟸   NM_001159615
- UniProtKB: A0A287A784 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000049177   ⟸   ENSSSCT00000054375
RefSeq Acc Id: ENSSSCP00000040087   ⟸   ENSSSCT00000042524
RefSeq Acc Id: ENSSSCP00000046493   ⟸   ENSSSCT00000048358
Protein Domains
IF rod


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000252 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070030246 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000040087 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000046493 UniProtKB/TrEMBL
  ENSSSCP00000049177 UniProtKB/TrEMBL
  ENSSSCP00070051872 UniProtKB/TrEMBL
  ENSSSCP00070051873 UniProtKB/TrEMBL
  ENSSSCP00070051875 UniProtKB/TrEMBL
  ENSSSCP00070051878 UniProtKB/TrEMBL
  ENSSSCP00070051881 UniProtKB/TrEMBL
  ENSSSCP00070051883 UniProtKB/TrEMBL
  ENSSSCP00070051885 UniProtKB/TrEMBL
  ENSSSCP00070051886 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042524 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000048358 UniProtKB/TrEMBL
  ENSSSCT00000054375 UniProtKB/TrEMBL
  ENSSSCT00070060865 UniProtKB/TrEMBL
  ENSSSCT00070060866 UniProtKB/TrEMBL
  ENSSSCT00070060868 UniProtKB/TrEMBL
  ENSSSCT00070060871 UniProtKB/TrEMBL
  ENSSSCT00070060874 UniProtKB/TrEMBL
  ENSSSCT00070060876 UniProtKB/TrEMBL
  ENSSSCT00070060878 UniProtKB/TrEMBL
  ENSSSCT00070060879 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1160 UniProtKB/TrEMBL
InterPro IF_conserved UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
  IF_rod_dom_coil1B UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/TrEMBL
  Keratin_II UniProtKB/TrEMBL
KEGG Report ssc:100152077 UniProtKB/TrEMBL
NCBI Gene KRT8 ENTREZGENE
Pfam Filament UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/TrEMBL
PRINTS TYPE2KERATIN UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
UniProt A0A287A784 ENTREZGENE
  A0A287A8E9_PIG UniProtKB/TrEMBL
  A0A287ARG4_PIG UniProtKB/TrEMBL
  A0A287AZ82_PIG UniProtKB/TrEMBL
  A0A4X1WBI1_PIG UniProtKB/TrEMBL
  A0A4X1WBI8_PIG UniProtKB/TrEMBL
  A0A4X1WBJ1_PIG UniProtKB/TrEMBL
  A0A4X1WBM0_PIG UniProtKB/TrEMBL
  A0A4X1WBM7_PIG UniProtKB/TrEMBL
  A0A4X1WBU0_PIG UniProtKB/TrEMBL
  A0A4X1WBU9_PIG UniProtKB/TrEMBL
  A0A4X1WD04_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89596 ENTREZGENE