LDLR (low density lipoprotein receptor) - Rat Genome Database

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Gene: LDLR (low density lipoprotein receptor) Homo sapiens
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Symbol: LDLR
Name: low density lipoprotein receptor
RGD ID: 735594
HGNC Page HGNC:6547
Description: Enables several functions, including low-density lipoprotein particle binding activity; low-density lipoprotein particle receptor activity; and very-low-density lipoprotein particle receptor activity. Involved in several processes, including cholesterol homeostasis; cholesterol transport; and long-term memory. Located in several cellular components, including clathrin-coated pit; endosome; and external side of plasma membrane. Part of PCSK9-LDLR complex and receptor complex. Implicated in Alzheimer's disease; arteriosclerosis; familial hypercholesterolemia; hepatitis C; and migraine without aura. Biomarker of systemic lupus erythematosus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FH; FHC; FHCL1; LDL receptor; LDLCQ2; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   BP50_H  
Candidate Gene For: BW138_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,089,463 - 11,133,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1911,089,462 - 11,133,820 (+)EnsemblGRCh38hg38GRCh38
GRCh371911,200,139 - 11,244,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,061,132 - 11,105,490 (+)NCBINCBI36Build 36hg18NCBI36
Build 341911,061,131 - 11,105,490NCBI
Celera1911,094,887 - 11,139,322 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,777,128 - 10,820,847 (+)NCBIHuRef
CHM1_11911,201,264 - 11,245,760 (+)NCBICHM1_1
T2T-CHM13v2.01911,216,460 - 11,260,830 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model