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Gene: DAPK3 (death associated protein kinase 3) Homo sapiens
Symbol: DAPK3
Name: death associated protein kinase 3
Description: Exhibits several functions, including ATP binding activity; leucine zipper domain binding activity; and protein homodimerization activity. Involved in several processes, including cellular response to interferon-gamma; regulation of actin cytoskeleton reorganization; and regulation of focal adhesion assembly. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DAP kinase 3; DAP-like kinase; death-associated like kinase; death-associated protein kinase 3; dlk; FLJ36473; MYPT1 kinase; ZIP; ZIP kinase isoform; ZIP-kinase; ZIPK; zipper-interacting protein kinase
Mus musculus (house mouse) : Dapk3 (death-associated protein kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dapk3 (death-associated protein kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dapk3 (death associated protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DAPK3 (death associated protein kinase 3)
Canis lupus familiaris (dog) : DAPK3 (death associated protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dapk3 (death associated protein kinase 3)
Sus scrofa (pig) : DAPK3 (death associated protein kinase 3)
Chlorocebus sabaeus (African green monkey) : DAPK3 (death associated protein kinase 3)
Heterocephalus glaber (naked mole-rat) : Dapk3 (death associated protein kinase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl193,958,453 - 3,971,123 (-)Ensembl
GRCh38193,958,453 - 3,971,099 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37193,958,451 - 3,971,097 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,909,452 - 3,920,826 (-)NCBINCBI36hg18NCBI36
Build 34193,909,451 - 3,920,826NCBI
Celera193,895,592 - 3,906,968 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,721,681 - 3,733,014 (-)NCBIHuRef
CHM1_1193,958,112 - 3,970,797 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DAPK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731385
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.