IGFBP3 (insulin like growth factor binding protein 3) - Rat Genome Database

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Gene: IGFBP3 (insulin like growth factor binding protein 3) Homo sapiens
Analyze
Symbol: IGFBP3
Name: insulin like growth factor binding protein 3
RGD ID: 736042
HGNC Page HGNC
Description: Enables insulin-like growth factor I binding activity and protein tyrosine phosphatase activator activity. Involved in several processes, including negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; and positive regulation of myoblast differentiation. Acts upstream of or within negative regulation of cell population proliferation; negative regulation of protein phosphorylation; and protein phosphorylation. Located in extracellular space and nucleus. Part of insulin-like growth factor ternary complex. Implicated in several diseases, including Alzheimer's disease; Turner syndrome; diabetes mellitus (multiple); prostate cancer; and transitional cell carcinoma. Biomarker of several diseases, including Barrett's esophagus; Down syndrome; autoimmune disease (multiple); bone disease (multiple); and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; IBP-3; IBP3; IGF-binding protein 3; IGFBP-3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl745,912,245 - 45,921,874 (-)EnsemblGRCh38hg38GRCh38
GRCh38745,912,245 - 45,921,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37745,951,844 - 45,960,871 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,918,369 - 45,927,396 (-)NCBINCBI36hg18NCBI36
Build 34745,725,189 - 45,734,057NCBI
Celera746,050,761 - 46,059,785 (-)NCBI
Cytogenetic Map7p12.3NCBI
HuRef745,836,799 - 45,845,824 (-)NCBIHuRef
CHM1_1745,956,047 - 45,965,072 (-)NCBICHM1_1
CRA_TCAGchr7v2745,991,173 - 46,000,198 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (IEP)
Acute-Phase Reaction  (IDA)
Alzheimer's disease  (IDA,IEP,ISO)
ankylosing spondylitis  (IEP)
arteriosclerosis  (IEP)
autistic disorder  (EXP)
Barrett's esophagus  (IEP)
beta thalassemia  (IEP)
breast cancer  (IAGP,IEP)
Burns  (ISO)
cervix uteri carcinoma in situ  (IEP)
Colorectal Neoplasms  (EXP)
Congenital Adrenal Hyperplasia due to 21 Hydroxylase Deficiency  (IEP)
congenital diaphragmatic hernia  (ISO)
congenital disorder of glycosylation Ia  (IEP)
Coronary Disease  (IDA)
COVID-19  (HEP)
cystic fibrosis  (IEP)
Down syndrome  (IEP)
Dwarfism  (IEP)
Endometrial Neoplasms  (IEP)
Endometrioid Carcinomas  (IEP)
Endotoxemia  (ISO)
epidermolysis bullosa dystrophica  (IEP)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP)
Fetal Growth Retardation  (IDA,IEP,ISO)
Fetal Macrosomia  (IEP)
Head Injuries, Closed  (IEP)
high grade glioma  (IEP)
Hypoxia-Ischemia, Brain  (ISO)
ichthyosis  (IEP)
impotence  (ISO)
inflammatory bowel disease  (IAGP)
Insulin Resistance  (IDA)
Malocclusion  (ISO)
McCune Albright syndrome  (IEP)
Metabolic Bone Diseases  (IDA)
myeloid leukemia  (IEP)
Myocardial Ischemia  (EXP)
obesity  (ISO)
ornithine carbamoyltransferase deficiency  (IEP)
osteoarthritis  (IEP)
osteoporosis  (IEP)
Ovarian Neoplasms  (IDA,IEP)
pleomorphic xanthoastrocytoma  (IAGP)
primary progressive multiple sclerosis  (IEP)
prostate cancer  (IAGP)
Prostatic Neoplasms  (EXP)
pulmonary fibrosis  (IEP)
renal cell carcinoma  (IEP)
retinopathy of prematurity  (IEP)
rheumatoid arthritis  (EXP)
Spinal Fractures  (IEP)
Spontaneous Abortions  (EXP)
Stomach Neoplasms  (EXP)
systemic scleroderma  (IEP)
tonsillitis  (IEP)
transitional cell carcinoma  (EXP,IDA)
Turner syndrome  (IDA)
type 1 diabetes mellitus  (IDA,IEP)
type 2 diabetes mellitus  (IDA)
urinary bladder cancer  (EXP,IEP)
Uterine Cervical Neoplasms  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(R)-lipoic acid  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,5-hexanedione  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (EXP)
2-methoxyethanol  (ISO)
2-methylcholine  (EXP)
2-nitrofluorene  (ISO)
2-nitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,4-dichloroaniline  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-4-oxoretinoic acid  (EXP)
all-trans-retinoic acid  (EXP,ISO)
aluminium sulfate (anhydrous)  (EXP)
ammonium chloride  (ISO)
ampicillin  (EXP)
aristolochic acid  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
azathioprine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (EXP)
bexarotene  (ISO)
bicalutamide  (EXP,ISO)
bilirubin IXalpha  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromochloroacetic acid  (ISO)
bucladesine  (EXP)
buta-1,3-diene  (ISO)
butanal  (EXP)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (EXP)
captan  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
cholesterol  (ISO)
cisplatin  (EXP)
clobetasol  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
CU-O LINKAGE  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP)
cytarabine  (EXP)
decabromodiphenyl ether  (EXP)
dehydroepiandrosterone  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dichlorine  (ISO)
diclofenac  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
diuron  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP)
entinostat  (EXP)
ethanol  (EXP)
fenamidone  (ISO)
flavonoids  (ISO)
flutamide  (EXP,ISO)
folic acid  (ISO)
folpet  (ISO)
fonofos  (EXP)
fructose  (ISO)
gadolinium trichloride  (ISO)
gemcitabine  (EXP)
genistein  (EXP)
glafenine  (ISO)
glutathione  (ISO)
glycidol  (ISO)
hexachlorobenzene  (EXP)
hydroquinone  (EXP)
indometacin  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
isoflavones  (EXP)
isoprenaline  (ISO)
isotretinoin  (EXP)
ivermectin  (ISO)
ketamine  (ISO)
leflunomide  (EXP)
levonorgestrel  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (ISO)
LY294002  (EXP)
medroxyprogesterone acetate  (EXP)
mercury dibromide  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methoxyacetic acid  (ISO)
methylmercury chloride  (EXP)
methylmercury(1+)  (ISO)
mifepristone  (EXP)
mitoxantrone  (EXP)
Monobutylphthalate  (ISO)
monosodium L-glutamate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
naphthalene  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
nickel subsulfide  (EXP)
nimesulide  (ISO)
nitrofen  (ISO)
nonanedioic acid  (ISO)
oxaliplatin  (EXP,ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (EXP)
p-toluidine  (ISO)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
parathion  (EXP)
PD 0325901  (EXP)
pentanal  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (ISO)
potassium dichromate  (ISO)
progesterone  (EXP,ISO)
propanal  (EXP)
propiconazole  (ISO)
quercetin  (EXP,ISO)
quinolin-8-ol  (EXP)
rac-lactic acid  (EXP)
raloxifene  (EXP)
resveratrol  (EXP)
rifampicin  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (EXP)
sirtinol  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
streptozocin  (ISO)
succimer  (EXP)
sulfasalazine  (ISO)
sunitinib  (EXP)
tamibarotene  (EXP)
tamoxifen  (EXP,ISO)
taurine  (EXP)
temozolomide  (EXP)
terbufos  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP,ISO)
testosterone undecanoate  (EXP)
Tetrachlorobisphenol A  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thalidomide  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
tioguanine  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP,ISO)
tremolite asbestos  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
troglitazone  (EXP)
tunicamycin  (EXP)
urethane  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vandetanib  (EXP)
vinclozolin  (ISO)
zearalenone  (EXP)
zebularine  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. Akintoye SO, etal., J Clin Endocrinol Metab. 2006 Aug;91(8):2960-6. Epub 2006 May 23.
2. Asthana S, etal., Psychoneuroendocrinology. 1999 Aug;24(6):657-77.
3. Baker Méio MD, etal., J Perinat Med. 2009;37(6):689-93. doi: 10.1515/JPM.2009.122.
4. Beeton CA, etal., J Bone Joint Surg Br. 2002 Apr;84(3):434-9.
5. Braz AF, etal., J Clin Endocrinol Metab. 2012 Apr;97(4):E671-7. doi: 10.1210/jc.2011-2521. Epub 2012 Jan 25.
6. Börzsönyi B, etal., J Perinat Med. 2011 Nov;39(6):701-7. doi: 10.1515/JPM.2011.090. Epub 2011 Aug 8.
7. Capoluongo E, etal., Cytokine. 2006 Jun;34(5-6):303-11. Epub 2006 Aug 2.
8. Chu DC, etal., Obstet Gynecol. 1998 Feb;91(2):192-5.
9. Chuang ST, etal., J Urol. 2008 Feb;179(2):445-9.
10. Clemmons DR, etal., Growth Horm IGF Res. 2005 Aug;15(4):265-74.
11. Collett-Solberg PF, etal., J Pediatr Endocrinol Metab. 2007 Feb;20(2):211-8.
12. Duan C and Xu Q, Gen Comp Endocrinol. 2005 May 15;142(1-2):44-52. Epub 2005 Feb 5.
13. Farmarzi M, etal., Iran J Otorhinolaryngol. 2016 Sep;28(88):329-335.
14. Fischer F, etal., Clin Endocrinol (Oxf). 2004 Nov;61(5):595-602.
15. Geyer M, etal., Osteoarthritis Cartilage. 2009 Mar;17(3):328-35. doi: 10.1016/j.joca.2008.07.010. Epub 2008 Sep 4.
16. Gharehbaghi MM, etal., Indian J Ophthalmol. 2012 Nov-Dec;60(6):527-30. doi: 10.4103/0301-4738.103782.
17. GOA_HUMAN data from the GO Consortium
18. Gravholt CH, etal., Am J Physiol Endocrinol Metab. 2001 Feb;280(2):E308-14.
19. Gravholt CH, etal., Growth Horm IGF Res. 2006 Oct-Dec;16(5-6):332-9. Epub 2006 Oct 25.
20. Grzelkowska-Kowalczyk K and Wieteska W, Pol J Vet Sci. 2005;8(3):231-40.
21. Hamaguchi Y, etal., J Rheumatol. 2008 Dec;35(12):2363-71. doi: 10.3899/jrheum.080340. Epub 2008 Nov 1.
22. Hernandez W, etal., Carcinogenesis. 2007 Oct;28(10):2154-9. Epub 2007 Aug 27.
23. Hinz S, etal., Tumour Biol. 2007;28(3):151-7. Epub 2007 Jun 1.
24. Hoyo C, etal., J Natl Med Assoc. 2007 Jul;99(7):718-22.
25. Ibanez de Caceres I, etal., Eur J Pharmacol. 2003 Nov 28;481(2-3):293-9.
26. Jeschke MG, etal., Ann Surg. 2000 Mar;231(3):408-16.
27. Johansson AG, etal., J Clin Endocrinol Metab. 1997 Sep;82(9):2795-8.
28. Johansson P, etal., Psychoneuroendocrinology. 2013 Sep;38(9):1729-37. doi: 10.1016/j.psyneuen.2013.02.006. Epub 2013 Mar 6.
29. Kaulsay KK, etal., Eur J Endocrinol. 1999 Feb;140(2):164-8.
30. Kawachi S, etal., Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):617-21. Epub 2004 Dec 29.
31. Kim HS, etal., Pediatr Res. 2007 Feb;61(2):159-64.
32. Kirman I, etal., Dig Dis Sci. 2005 Apr;50(4):780-4.
33. Koklu E, etal., Growth Horm IGF Res. 2007 Feb;17(1):26-32. Epub 2006 Nov 20.
34. Kurtoglu S, etal., J Pediatr Endocrinol Metab. 2008 Jul;21(7):689-94.
35. Lang CH, etal., Am J Physiol Endocrinol Metab. 2000 Jun;278(6):E1087-96.
36. Lee WH, etal., Endocrine. 1999 Oct;11(2):181-8.
37. Li L, etal., Cancer Epidemiol Biomarkers Prev. 2004 Mar;13(3):497-8.
38. Low LC, etal., Clin Endocrinol (Oxf). 1998 May;48(5):641-6.
39. Lu Y, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2006 Aug;8(4):319-22.
40. Mallipeddi R, etal., J Invest Dermatol. 2004 May;122(5):1302-9.
41. Martin AI, etal., J Endocrinol. 2008 Aug;198(2):385-94. doi: 10.1677/JOE-08-0205. Epub 2008 May 20.
42. Mathur SP, etal., Gynecol Oncol. 2003 Dec;91(3):486-93.
43. Miller BS, etal., Clin Endocrinol (Oxf). 2009 Jun;70(6):892-7. doi: 10.1111/j.1365-2265.2009.03531.x. Epub 2009 Jan 22.
44. Murisier-Petetin G, etal., Eur J Obstet Gynecol Reprod Biol. 2009 May;144(1):15-20. doi: 10.1016/j.ejogrb.2009.01.004. Epub 2009 Feb 13.
45. Nagasaka H, etal., Eur J Pediatr. 2006 Sep;165(9):618-24. Epub 2006 May 16.
46. Narusawa K, etal., J Bone Miner Res. 1995 Dec;10(12):1853-64.
47. Oh JC, etal., Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):748-52.
48. Ozen M, etal., Pediatr Int. 2004 Aug;46(4):429-35.
49. Palau N, etal., Endocrinology. 2012 Jan;153(1):177-87. doi: 10.1210/en.2011-0181. Epub 2011 Nov 8.
50. Pazaitou-Panayiotou K, etal., Eur J Endocrinol. 2007 Feb;156(2):187-94.
51. Pilewski JM, etal., Am J Pathol. 2005 Feb;166(2):399-407.
52. Pipeline to import KEGG annotations from KEGG into RGD
53. Pu XY, etal., J Sex Med. 2011 Aug;8(8):2181-90. doi: 10.1111/j.1743-6109.2011.02318.x. Epub 2011 May 19.
54. Pu XY, etal., J Urol. 2014 Sep;192(3):990-6. doi: 10.1016/j.juro.2014.02.042. Epub 2014 Feb 24.
55. Qiu XS, etal., Chin Med Sci J. 2004 Sep;19(3):189-92.
56. Ren Z, etal., Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1290-5.
57. RGD automated import pipeline for gene-chemical interactions
58. Rohrmann S, etal., Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2174-82. doi: 10.1158/1055-9965.EPI-11-0179. Epub 2011 Jul 25.
59. Ruttenstock E, etal., Pediatr Surg Int. 2010 Jan;26(1):59-63. doi: 10.1007/s00383-009-2509-5.
60. Saukkonen T, etal., J Clin Endocrinol Metab. 2004 Sep;89(9):4634-41.
61. Schernhammer ES, etal., Int J Cancer. 2003 Oct 20;107(1):60-4.
62. Serrano ML, etal., Growth Horm IGF Res. 2007 Dec;17(6):492-9. Epub 2007 Aug 20.
63. Siahpush SH, etal., Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2387-95.
64. Soh J, etal., Urology. 2007 Nov;70(5):1019-23.
65. Su AL, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2011 Sep;13(9):700-3.
66. Sugimoto T, etal., J Bone Miner Res. 1997 Aug;12(8):1272-9.
67. Sung HY, etal., PLoS One. 2014 Jun 25;9(6):e99047. doi: 10.1371/journal.pone.0099047. eCollection 2014.
68. Torng PL, etal., Oncogene. 2008 Apr 3;27(15):2137-47. Epub 2007 Oct 22.
69. Toussirot E, etal., Br J Rheumatol. 1998 Nov;37(11):1172-6.
70. Ulmer A, etal., Klin Padiatr. 2013 May;225(3):120-6. doi: 10.1055/s-0033-1343483. Epub 2013 May 28.
71. Völkl TM, etal., Growth Horm IGF Res. 2011 Aug;21(4):191-8. doi: 10.1016/j.ghir.2011.05.001. Epub 2011 Jun 1.
72. Wagner K, etal., Breast Cancer Res Treat. 2007 Sep;104(3):233-48. Epub 2006 Nov 2.
73. Walker G, etal., Clin Cancer Res. 2007 Mar 1;13(5):1438-44.
74. Wilczak N, etal., Mult Scler. 2005 Feb;11(1):13-5.
75. Wiley A, etal., Int J Gynecol Cancer. 2006 Jan-Feb;16(1):210-8.
76. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
77. Yu S, etal., J Oral Rehabil. 2012 Oct;39(10):727-36. doi: 10.1111/j.1365-2842.2012.02332.x. Epub 2012 Jul 3.
78. Zhao H, etal., J Urol. 2003 Feb;169(2):714-7.
79. Zhou ZY, etal., Med Sci Monit. 2015 Jan 8;21:94-9. doi: 10.12659/MSM.891382.
Additional References at PubMed
PMID:1280211   PMID:1293182   PMID:1373120   PMID:1383255   PMID:1695633   PMID:1697583   PMID:2464130   PMID:7508771   PMID:7523391   PMID:7538844   PMID:7566179   PMID:8550744  
PMID:8675597   PMID:8708531   PMID:8843739   PMID:8964576   PMID:9252371   PMID:9275067   PMID:9337997   PMID:9388210   PMID:9389554   PMID:9408744   PMID:9446566   PMID:9497324  
PMID:9688635   PMID:10076184   PMID:10218588   PMID:10226805   PMID:10352394   PMID:10407151   PMID:10511594   PMID:10512690   PMID:10650937   PMID:10766744   PMID:10770214   PMID:10811646  
PMID:10823924   PMID:10849447   PMID:10874028   PMID:11095942   PMID:11238520   PMID:11264294   PMID:11297622   PMID:11319179   PMID:11344214   PMID:11375929   PMID:11600567   PMID:11749962  
PMID:11751851   PMID:11762714   PMID:11784719   PMID:11801256   PMID:11804742   PMID:11886859   PMID:11914023   PMID:11914026   PMID:11940579   PMID:11948969   PMID:11953210   PMID:11959812  
PMID:11971816   PMID:11997031   PMID:12006706   PMID:12011225   PMID:12051736   PMID:12054563   PMID:12068000   PMID:12111701   PMID:12122101   PMID:12127836   PMID:12135130   PMID:12150454  
PMID:12163384   PMID:12200149   PMID:12210764   PMID:12213898   PMID:12219010   PMID:12220677   PMID:12242693   PMID:12473575   PMID:12477932   PMID:12506097   PMID:12508918   PMID:12519841  
PMID:12571183   PMID:12571851   PMID:12575534   PMID:12590636   PMID:12599210   PMID:12690205   PMID:12725526   PMID:12730416   PMID:12735930   PMID:12810533   PMID:12810534   PMID:12853948  
PMID:12865482   PMID:12870155   PMID:12907612   PMID:12926118   PMID:12937269   PMID:12962157   PMID:14561895   PMID:14576163   PMID:14576164   PMID:14597676   PMID:14598881   PMID:14644829  
PMID:14674122   PMID:14693733   PMID:14702039   PMID:14710345   PMID:14718574   PMID:14744783   PMID:14751238   PMID:14760718   PMID:15014034   PMID:15047131   PMID:15059907   PMID:15066922  
PMID:15067329   PMID:15069073   PMID:15070968   PMID:15086466   PMID:15126567   PMID:15178549   PMID:15198293   PMID:15221971   PMID:15247132   PMID:15247904   PMID:15282325   PMID:15302288  
PMID:15340161   PMID:15379965   PMID:15448002   PMID:15485880   PMID:15489334   PMID:15517912   PMID:15641262   PMID:15641264   PMID:15642160   PMID:15642732   PMID:15651061   PMID:15661050  
PMID:15668470   PMID:15703779   PMID:15734965   PMID:15769996   PMID:15781645   PMID:15800934   PMID:15802501   PMID:15809062   PMID:15817480   PMID:15894673   PMID:15894694   PMID:15927849  
PMID:15941947   PMID:15959422   PMID:15986122   PMID:15987847   PMID:16015705   PMID:16030120   PMID:16049980   PMID:16169070   PMID:16181731   PMID:16189247   PMID:16189260   PMID:16210470  
PMID:16211216   PMID:16215864   PMID:16275148   PMID:16303743   PMID:16306136   PMID:16322329   PMID:16335952   PMID:16394092   PMID:16404426   PMID:16448675   PMID:16455777   PMID:16489075  
PMID:16489531   PMID:16540651   PMID:16541420   PMID:16543235   PMID:16552541   PMID:16614079   PMID:16617154   PMID:16645643   PMID:16723126   PMID:16763062   PMID:16775172   PMID:16776662  
PMID:16793770   PMID:16825320   PMID:16915540   PMID:16935391   PMID:16965600   PMID:16969385   PMID:17018785   PMID:17035411   PMID:17044098   PMID:17047053   PMID:17051426   PMID:17056474  
PMID:17063263   PMID:17070193   PMID:17085968   PMID:17096329   PMID:17113753   PMID:17119061   PMID:17172410   PMID:17187018   PMID:17210081   PMID:17264182   PMID:17289909   PMID:17293864  
PMID:17297462   PMID:17300730   PMID:17350302   PMID:17388800   PMID:17434446   PMID:17434920   PMID:17446556   PMID:17447118   PMID:17453001   PMID:17457048   PMID:17546465   PMID:17555512  
PMID:17560154   PMID:17566087   PMID:17567756   PMID:17577982   PMID:17591901   PMID:17593323   PMID:17597108   PMID:17624927   PMID:17627014   PMID:17635417   PMID:17655506   PMID:17689128  
PMID:17719815   PMID:17761791   PMID:17763192   PMID:17803702   PMID:17823260   PMID:17827406   PMID:17879951   PMID:17912004   PMID:17957164   PMID:17959403   PMID:17972510   PMID:17997337  
PMID:18031946   PMID:18059035   PMID:18084616   PMID:18162523   PMID:18163429   PMID:18171112   PMID:18177247   PMID:18178497   PMID:18259111   PMID:18287864   PMID:18329388   PMID:18335323  
PMID:18375957   PMID:18398029   PMID:18410545   PMID:18450319   PMID:18459102   PMID:18471292   PMID:18481170   PMID:18498652   PMID:18534134   PMID:18562769   PMID:18596909   PMID:18602100  
PMID:18615538   PMID:18618736   PMID:18624627   PMID:18636124   PMID:18676680   PMID:18812263   PMID:18818748   PMID:18929499   PMID:18984657   PMID:18992148   PMID:18992263   PMID:19019335  
PMID:19020726   PMID:19036873   PMID:19064126   PMID:19064572   PMID:19077426   PMID:19121847   PMID:19124506   PMID:19124510   PMID:19127217   PMID:19129715   PMID:19138871   PMID:19158946  
PMID:19170196   PMID:19190540   PMID:19194113   PMID:19223521   PMID:19240240   PMID:19257984   PMID:19258508   PMID:19332270   PMID:19414355   PMID:19449212   PMID:19453261   PMID:19455605  
PMID:19477944   PMID:19491931   PMID:19492232   PMID:19509068   PMID:19527514   PMID:19540231   PMID:19551141   PMID:19551864   PMID:19556345   PMID:19568604   PMID:19588500   PMID:19596932  
PMID:19625176   PMID:19633297   PMID:19634593   PMID:19672706   PMID:19692168   PMID:19734278   PMID:19764562   PMID:19784788   PMID:19786462   PMID:19786971   PMID:19789190   PMID:19800385  
PMID:19833751   PMID:19845745   PMID:19846909   PMID:19858071   PMID:19863750   PMID:19913121   PMID:19917654   PMID:19919528   PMID:19938081   PMID:19941883   PMID:19944347   PMID:19948975  
PMID:19960406   PMID:20003326   PMID:20023704   PMID:20039319   PMID:20051649   PMID:20084546   PMID:20099974   PMID:20102313   PMID:20119675   PMID:20121533   PMID:20144192   PMID:20145156  
PMID:20155489   PMID:20204283   PMID:20215856   PMID:20219400   PMID:20228135   PMID:20302654   PMID:20307522   PMID:20350746   PMID:20353938   PMID:20357812   PMID:20378848   PMID:20403354  
PMID:20416304   PMID:20423985   PMID:20427254   PMID:20453000   PMID:20468064   PMID:20484221   PMID:20501753   PMID:20513670   PMID:20540360   PMID:20580999   PMID:20587610   PMID:20599318  
PMID:20613589   PMID:20628086   PMID:20628624   PMID:20634197   PMID:20677014   PMID:20731527   PMID:20734064   PMID:20801067   PMID:20810604   PMID:20848532   PMID:20851879   PMID:20860465  
PMID:20884247   PMID:20889360   PMID:20920870   PMID:20921904   PMID:20945273   PMID:21068693   PMID:21076409   PMID:21078522   PMID:21140206   PMID:21195059   PMID:21216879   PMID:21254935  
PMID:21347663   PMID:21378090   PMID:21383009   PMID:21388950   PMID:21392749   PMID:21435441   PMID:21447628   PMID:21447640   PMID:21455575   PMID:21471542   PMID:21474793   PMID:21478207  
PMID:21520041   PMID:21520165   PMID:21521316   PMID:21525788   PMID:21529443   PMID:21536375   PMID:21536469   PMID:21551235   PMID:21562710   PMID:21585623   PMID:21648284   PMID:21697095  
PMID:21698457   PMID:21701930   PMID:21737444   PMID:21761353   PMID:21852217   PMID:21873635   PMID:21892705   PMID:21898383   PMID:21930730   PMID:21944866   PMID:22001433   PMID:22004906  
PMID:22026507   PMID:22032863   PMID:22085490   PMID:22113073   PMID:22128038   PMID:22167391   PMID:22246875   PMID:22253890   PMID:22318747   PMID:22328165   PMID:22332214   PMID:22347413  
PMID:22363400   PMID:22381038   PMID:22389159   PMID:22415309   PMID:22415807   PMID:22441125   PMID:22442270   PMID:22475139   PMID:22494072   PMID:22500655   PMID:22527168   PMID:22543588  
PMID:22554827   PMID:22565227   PMID:22643116   PMID:22739332   PMID:22745191   PMID:22751133   PMID:22778398   PMID:22801219   PMID:22847383   PMID:22879989   PMID:22882716   PMID:22884472  
PMID:22892437   PMID:22894543   PMID:22898364   PMID:22936258   PMID:22951368   PMID:23011725   PMID:23036517   PMID:23041555   PMID:23158139   PMID:23174226   PMID:23178489   PMID:23185474  
PMID:23341348   PMID:23348700   PMID:23376485   PMID:23377640   PMID:23383064   PMID:23464449   PMID:23498137   PMID:23527244   PMID:23527725   PMID:23592916   PMID:23611528   PMID:23619263  
PMID:23720424   PMID:23748063   PMID:23770368   PMID:23784592   PMID:23789983   PMID:23792502   PMID:23831640   PMID:23864804   PMID:23878061   PMID:23962053   PMID:24022308   PMID:24051179  
PMID:24094144   PMID:24175768   PMID:24310658   PMID:24337110   PMID:24339922   PMID:24351920   PMID:24368776   PMID:24379526   PMID:24386080   PMID:24412244   PMID:24451943   PMID:24457161  
PMID:24464126   PMID:24586243   PMID:24587638   PMID:24785566   PMID:24809065   PMID:24811788   PMID:24825082   PMID:24878287   PMID:24905466   PMID:24915949   PMID:24926947   PMID:24928840  
PMID:24938707   PMID:24942865   PMID:24943688   PMID:24953254   PMID:25028991   PMID:25059666   PMID:25081695   PMID:25086184   PMID:25108383   PMID:25120154   PMID:25127039   PMID:25179796  
PMID:25277046   PMID:25285521   PMID:25295265   PMID:25385317   PMID:25385818   PMID:25449421   PMID:25482372   PMID:25525174   PMID:25548030   PMID:25552351   PMID:25553725   PMID:25556430  
PMID:25619494   PMID:25662950   PMID:25739014   PMID:25742716   PMID:25822686   PMID:25945837   PMID:25947142   PMID:25960224   PMID:25966104   PMID:25987030   PMID:26063735   PMID:26068014  
PMID:26069074   PMID:26074086   PMID:26121987   PMID:26216267   PMID:26323436   PMID:26349977   PMID:26378048   PMID:26388613   PMID:26540630   PMID:26637371   PMID:26662570   PMID:26670461  
PMID:26731648   PMID:26887040   PMID:26893016   PMID:26902691   PMID:26975989   PMID:27035126   PMID:27070751   PMID:27071409   PMID:27089405   PMID:27094973   PMID:27111220   PMID:27144338  
PMID:27223680   PMID:27329260   PMID:27455178   PMID:27521890   PMID:27563882   PMID:27579675   PMID:27631779   PMID:27658775   PMID:27704894   PMID:27755861   PMID:27775453   PMID:27978831  
PMID:28073843   PMID:28246273   PMID:28300542   PMID:28330997   PMID:28378642   PMID:28393842   PMID:28484923   PMID:28551677   PMID:28596684   PMID:28609827   PMID:28653360   PMID:28681154  
PMID:28724170   PMID:28778177   PMID:28859160   PMID:29040592   PMID:29044573   PMID:29112142   PMID:29112184   PMID:29219174   PMID:29453428   PMID:29473153   PMID:29547749   PMID:29579543  
PMID:29739044   PMID:29772705   PMID:29855605   PMID:29926665   PMID:29947889   PMID:30078228   PMID:30084561   PMID:30106114   PMID:30184438   PMID:30290787   PMID:30328477   PMID:30334445  
PMID:30335898   PMID:30429106   PMID:30641835   PMID:30643822   PMID:30725116   PMID:30761980   PMID:30815935   PMID:30898176   PMID:31045453   PMID:31085806   PMID:31165486   PMID:31218761  
PMID:31366504   PMID:31513316   PMID:31713889   PMID:31884074   PMID:31961798   PMID:31978779   PMID:31996369   PMID:32065979   PMID:32066763   PMID:32129151   PMID:32193421   PMID:32383868  
PMID:32492897   PMID:32567791   PMID:32656927   PMID:32703944   PMID:32782147   PMID:32799208   PMID:32814053   PMID:33149205   PMID:33188835   PMID:33256984   PMID:33401705   PMID:33436560  
PMID:33845483   PMID:34001234  


Genomics

Comparative Map Data
IGFBP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl745,912,245 - 45,921,874 (-)EnsemblGRCh38hg38GRCh38
GRCh38745,912,245 - 45,921,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37745,951,844 - 45,960,871 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,918,369 - 45,927,396 (-)NCBINCBI36hg18NCBI36
Build 34745,725,189 - 45,734,057NCBI
Celera746,050,761 - 46,059,785 (-)NCBI
Cytogenetic Map7p12.3NCBI
HuRef745,836,799 - 45,845,824 (-)NCBIHuRef
CHM1_1745,956,047 - 45,965,072 (-)NCBICHM1_1
CRA_TCAGchr7v2745,991,173 - 46,000,198 (-)NCBI
Igfbp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,156,086 - 7,165,498 (-)NCBIGRCm39mm39
GRCm39 Ensembl117,156,086 - 7,163,923 (-)Ensembl
GRCm38117,206,086 - 7,215,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,206,086 - 7,213,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv37117,106,089 - 7,113,926 (-)NCBIGRCm37mm9NCBIm37
MGSCv36117,108,384 - 7,113,834 (-)NCBImm8
Celera117,681,286 - 7,689,161 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
Igfbp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21482,056,347 - 82,064,083 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1487,457,647 - 87,465,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01487,457,647 - 87,465,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01481,091,987 - 81,099,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,959,153 - 87,967,085 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11487,978,297 - 87,986,223 (-)NCBI
Celera1481,130,767 - 81,138,473 (-)NCBICelera
RH 3.4 Map14598.5RGD
Cytogenetic Map14q21NCBI
Igfbp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,795,604 - 6,800,845 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,795,560 - 6,802,147 (+)NCBIChiLan1.0ChiLan1.0
IGFBP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1746,681,856 - 46,690,240 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0746,564,234 - 46,573,145 (-)NCBIMhudiblu_PPA_v0panPan3
IGFBP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,021,855 - 1,027,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,021,972 - 1,026,392 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha161,797,939 - 1,804,689 (+)NCBI
ROS_Cfam_1.0161,008,571 - 1,015,327 (+)NCBI
UMICH_Zoey_3.116999,220 - 1,005,969 (+)NCBI
UNSW_CanFamBas_1.016934,846 - 941,592 (+)NCBI
UU_Cfam_GSD_1.016233,123 - 239,875 (-)NCBI
Igfbp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,299,235 - 101,306,540 (-)NCBI
SpeTri2.0NW_00493647820,511,490 - 20,518,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11850,002,921 - 50,009,425 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,851,168 - 54,855,699 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap18q24NCBI
IGFBP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,905,309 - 12,914,199 (+)NCBI
ChlSab1.1 Ensembl2112,905,280 - 12,914,205 (+)Ensembl
Vero_WHO_p1.0NW_0236660629,622,694 - 9,631,602 (-)NCBI
Igfbp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247406,878,818 - 6,886,512 (+)NCBI

Position Markers
STS-M35878  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,951,909 - 45,952,121UniSTSGRCh37
Build 36745,918,434 - 45,918,646RGDNCBI36
Celera746,050,826 - 46,051,038RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,836,864 - 45,837,076UniSTS
CRA_TCAGchr7v2745,991,238 - 45,991,450UniSTS
GeneMap99-GB4 RH Map7216.65UniSTS
NCBI RH Map7670.1UniSTS
D7S2379  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,952,067 - 45,952,242UniSTSGRCh37
Build 36745,918,592 - 45,918,767RGDNCBI36
Celera746,050,984 - 46,051,159RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,837,022 - 45,837,197UniSTS
CRA_TCAGchr7v2745,991,396 - 45,991,571UniSTS
Whitehead-YAC Contig Map7 UniSTS
D7S2146E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,956,164 - 45,956,896UniSTSGRCh37
Build 36745,922,689 - 45,923,421RGDNCBI36
Celera746,055,080 - 46,055,812RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,841,118 - 45,841,850UniSTS
CRA_TCAGchr7v2745,995,491 - 45,996,223UniSTS
D7S2833  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,953,043 - 45,953,387UniSTSGRCh37
Build 36745,919,568 - 45,919,912RGDNCBI36
Celera746,051,960 - 46,052,304RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,837,998 - 45,838,342UniSTS
CRA_TCAGchr7v2745,992,372 - 45,992,716UniSTS
Whitehead-YAC Contig Map7 UniSTS
IGFBP3-5'1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,961,361 - 45,962,020UniSTSGRCh37
Build 36745,927,886 - 45,928,545RGDNCBI36
Celera746,060,275 - 46,060,934RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,846,314 - 45,846,973UniSTS
CRA_TCAGchr7v2746,000,688 - 46,001,347UniSTS
IGFBP3-X2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,956,719 - 45,957,110UniSTSGRCh37
Build 36745,923,244 - 45,923,635RGDNCBI36
Celera746,055,635 - 46,056,026RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,841,673 - 45,842,064UniSTS
CRA_TCAGchr7v2745,996,046 - 45,996,437UniSTS
IGFBP3-X3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,956,001 - 45,956,470UniSTSGRCh37
Build 36745,922,526 - 45,922,995RGDNCBI36
Celera746,054,917 - 46,055,386RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,840,955 - 45,841,424UniSTS
CRA_TCAGchr7v2745,995,328 - 45,995,797UniSTS
IGFBP3-X4.2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,953,463 - 45,954,122UniSTSGRCh37
Build 36745,919,988 - 45,920,647RGDNCBI36
Celera746,052,380 - 46,053,039RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,838,418 - 45,839,077UniSTS
CRA_TCAGchr7v2745,992,792 - 45,993,451UniSTS
IGFBP3-X4.3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,952,939 - 45,953,583UniSTSGRCh37
Build 36745,919,464 - 45,920,108RGDNCBI36
Celera746,051,856 - 46,052,500RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,837,894 - 45,838,538UniSTS
CRA_TCAGchr7v2745,992,268 - 45,992,912UniSTS
IGFBP3-X4.4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,952,393 - 45,953,038UniSTSGRCh37
Build 36745,918,918 - 45,919,563RGDNCBI36
Celera746,051,310 - 46,051,955RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,837,348 - 45,837,993UniSTS
CRA_TCAGchr7v2745,991,722 - 45,992,367UniSTS
IGFBP3-X4.5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,951,904 - 45,952,509UniSTSGRCh37
Build 36745,918,429 - 45,919,034RGDNCBI36
Celera746,050,821 - 46,051,426RGD
Cytogenetic Map7p13-p12UniSTS
HuRef745,836,859 - 45,837,464UniSTS
CRA_TCAGchr7v2745,991,233 - 45,991,838UniSTS
IGFBP3_1859  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37745,952,467 - 45,953,282UniSTSGRCh37
Build 36745,918,992 - 45,919,807RGDNCBI36
Celera746,051,384 - 46,052,199RGD
HuRef745,837,422 - 45,838,237UniSTS
CRA_TCAGchr7v2745,991,796 - 45,992,611UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2033
Count of miRNA genes:826
Interacting mature miRNAs:941
Transcripts:ENST00000275521, ENST00000381083, ENST00000381086, ENST00000417621, ENST00000428530, ENST00000448817, ENST00000460209, ENST00000460477, ENST00000465642
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 6 12 3 2 2 35 4 6 84 65 22 1 20 1 1
Medium 2293 2206 1490 603 558 450 3970 1880 1459 311 1156 1466 164 1184 2534 1
Low 95 500 221 15 675 9 346 292 2153 22 217 82 5 253 2
Below cutoff 23 264 3 1 524 1 3 10 88 2 14 23 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001013398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF370418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI142967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK056274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK091706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK091745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK092447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK125224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK127537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK130884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL540642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU102436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ301819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ884396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ884397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ884398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S56205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000275521   ⟹   ENSP00000275521
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,912,598 - 45,921,274 (-)Ensembl
RefSeq Acc Id: ENST00000381083   ⟹   ENSP00000370473
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,912,245 - 45,921,272 (-)Ensembl
RefSeq Acc Id: ENST00000381086   ⟹   ENSP00000370476
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,912,245 - 45,921,272 (-)Ensembl
RefSeq Acc Id: ENST00000417621   ⟹   ENSP00000399116
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,914,470 - 45,917,426 (-)Ensembl
RefSeq Acc Id: ENST00000428530   ⟹   ENSP00000390298
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,914,101 - 45,917,397 (-)Ensembl
RefSeq Acc Id: ENST00000448817   ⟹   ENSP00000389668
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,916,572 - 45,921,874 (-)Ensembl
RefSeq Acc Id: ENST00000460209
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,913,773 - 45,915,325 (-)Ensembl
RefSeq Acc Id: ENST00000460477
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,916,996 - 45,920,867 (-)Ensembl
RefSeq Acc Id: ENST00000465642
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,916,621 - 45,920,415 (-)Ensembl
RefSeq Acc Id: ENST00000613132   ⟹   ENSP00000477772
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,912,251 - 45,921,140 (-)Ensembl
RefSeq Acc Id: ENST00000615754   ⟹   ENSP00000480717
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl745,914,820 - 45,921,140 (-)Ensembl
RefSeq Acc Id: NM_000598   ⟹   NP_000589
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38745,912,245 - 45,921,272 (-)NCBI
GRCh37745,951,844 - 45,960,871 (-)ENTREZGENE
Build 36745,918,369 - 45,927,396 (-)NCBI Archive
HuRef745,836,799 - 45,845,824 (-)ENTREZGENE
CHM1_1745,956,047 - 45,965,072 (-)NCBI
CRA_TCAGchr7v2745,991,173 - 46,000,198 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001013398   ⟹   NP_001013416
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38745,912,245 - 45,921,272 (-)NCBI
GRCh37745,951,844 - 45,960,871 (-)ENTREZGENE
Build 36745,918,369 - 45,927,396 (-)NCBI Archive
HuRef745,836,799 - 45,845,824 (-)ENTREZGENE
CHM1_1745,956,047 - 45,965,072 (-)NCBI
CRA_TCAGchr7v2745,991,173 - 46,000,198 (-)ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_000589 (Get FASTA)   NCBI Sequence Viewer  
  NP_001013416 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA52541 (Get FASTA)   NCBI Sequence Viewer  
  AAA52706 (Get FASTA)   NCBI Sequence Viewer  
  AAH00013 (Get FASTA)   NCBI Sequence Viewer  
  AAH18962 (Get FASTA)   NCBI Sequence Viewer  
  AAH64987 (Get FASTA)   NCBI Sequence Viewer  
  AAQ15254 (Get FASTA)   NCBI Sequence Viewer  
  AAS07554 (Get FASTA)   NCBI Sequence Viewer  
  ABB96247 (Get FASTA)   NCBI Sequence Viewer  
  ABI63363 (Get FASTA)   NCBI Sequence Viewer  
  ABI63364 (Get FASTA)   NCBI Sequence Viewer  
  ABI63365 (Get FASTA)   NCBI Sequence Viewer  
  BAC87023 (Get FASTA)   NCBI Sequence Viewer  
  BAG38033 (Get FASTA)   NCBI Sequence Viewer  
  BAG51662 (Get FASTA)   NCBI Sequence Viewer  
  BAG52153 (Get FASTA)   NCBI Sequence Viewer  
  BAG52402 (Get FASTA)   NCBI Sequence Viewer  
  BAG52410 (Get FASTA)   NCBI Sequence Viewer  
  BAG52553 (Get FASTA)   NCBI Sequence Viewer  
  BAG53151 (Get FASTA)   NCBI Sequence Viewer  
  BAG53162 (Get FASTA)   NCBI Sequence Viewer  
  BAG53182 (Get FASTA)   NCBI Sequence Viewer  
  BAG53189 (Get FASTA)   NCBI Sequence Viewer  
  BAG53771 (Get FASTA)   NCBI Sequence Viewer  
  BAG53948 (Get FASTA)   NCBI Sequence Viewer  
  BAG54169 (Get FASTA)   NCBI Sequence Viewer  
  BAG60115 (Get FASTA)   NCBI Sequence Viewer  
  BAG60419 (Get FASTA)   NCBI Sequence Viewer  
  CAA46087 (Get FASTA)   NCBI Sequence Viewer  
  EAL23801 (Get FASTA)   NCBI Sequence Viewer  
  EAW61025 (Get FASTA)   NCBI Sequence Viewer  
  EAW61026 (Get FASTA)   NCBI Sequence Viewer  
  EAW61027 (Get FASTA)   NCBI Sequence Viewer  
  EAW61028 (Get FASTA)   NCBI Sequence Viewer  
  EAW61029 (Get FASTA)   NCBI Sequence Viewer  
  P17936 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_000589   ⟸   NM_000598
- Peptide Label: isoform b precursor
- UniProtKB: P17936 (UniProtKB/Swiss-Prot),   B3KPF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001013416   ⟸   NM_001013398
- Peptide Label: isoform a precursor
- UniProtKB: P17936 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000390298   ⟸   ENST00000428530
RefSeq Acc Id: ENSP00000477772   ⟸   ENST00000613132
RefSeq Acc Id: ENSP00000399116   ⟸   ENST00000417621
RefSeq Acc Id: ENSP00000480717   ⟸   ENST00000615754
RefSeq Acc Id: ENSP00000275521   ⟸   ENST00000275521
RefSeq Acc Id: ENSP00000389668   ⟸   ENST00000448817
RefSeq Acc Id: ENSP00000370476   ⟸   ENST00000381086
RefSeq Acc Id: ENSP00000370473   ⟸   ENST00000381083
Promoters
RGD ID:6805798
Promoter ID:HG_KWN:57313
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:OTTHUMT00000340051
Position:
Human AssemblyChrPosition (strand)Source
Build 36745,921,046 - 45,921,546 (-)MPROMDB
RGD ID:7210547
Promoter ID:EPDNEW_H11019
Type:initiation region
Name:IGFBP3_1
Description:insulin like growth factor binding protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38745,921,272 - 45,921,332EPDNEW
RGD ID:6805801
Promoter ID:HG_KWN:57314
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3
Transcripts:OTTHUMT00000340052,   OTTHUMT00000340053
Position:
Human AssemblyChrPosition (strand)Source
Build 36745,923,196 - 45,924,097 (-)MPROMDB
RGD ID:6805549
Promoter ID:HG_KWN:57315
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   HeLa_S3
Transcripts:ENST00000381086,   NM_001013398,   OTTHUMT00000251356,   OTTHUMT00000340036,   OTTHUMT00000340048,   OTTHUMT00000340049,   OTTHUMT00000340050,   UC003TNQ.1,   UC003TNT.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36745,926,974 - 45,927,474 (-)MPROMDB
RGD ID:6850626
Promoter ID:EP73107
Type:single initiation site
Name:HS_IGFBP3
Description:Insulin-like growth factor binding protein 3.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 36745,927,396 - 45,927,456EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7p13-12.3(chr7:44193369-46558381)x1 copy number loss See cases [RCV000052316] Chr7:44193369..46558381 [GRCh38]
Chr7:44232968..46597979 [GRCh37]
Chr7:44199493..46564504 [NCBI36]
Chr7:7p13-12.3
pathogenic
GRCh38/hg38 7p14.3-q11.21(chr7:33328312-62377476)x3 copy number gain See cases [RCV000053532] Chr7:33328312..62377476 [GRCh38]
Chr7:33367924..61831899 [GRCh37]
Chr7:33334449..61469334 [NCBI36]
Chr7:7p14.3-q11.21
pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7p13-12.1(chr7:44571949-53699760)x1 copy number loss See cases [RCV000134973] Chr7:44571949..53699760 [GRCh38]
Chr7:44611548..53767453 [GRCh37]
Chr7:44578073..53734947 [NCBI36]
Chr7:7p13-12.1
pathogenic
GRCh38/hg38 7p14.1-11.2(chr7:40534157-56107122)x1 copy number loss See cases [RCV000136092] Chr7:40534157..56107122 [GRCh38]
Chr7:40573756..56174815 [GRCh37]
Chr7:40540281..56142309 [NCBI36]
Chr7:7p14.1-11.2
pathogenic
GRCh38/hg38 7p14.1-12.1(chr7:40020598-50543500)x1 copy number loss See cases [RCV000136904] Chr7:40020598..50543500 [GRCh38]
Chr7:40060197..50611198 [GRCh37]
Chr7:40026722..50578692 [NCBI36]
Chr7:7p14.1-12.1
pathogenic
GRCh38/hg38 7p14.1-12.3(chr7:37303478-48660738)x1 copy number loss See cases [RCV000137139] Chr7:37303478..48660738 [GRCh38]
Chr7:37343082..48700334 [GRCh37]
Chr7:37309607..48670880 [NCBI36]
Chr7:7p14.1-12.3
pathogenic
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p14.1-12.3(chr7:40350383-47034422)x1 copy number loss See cases [RCV000446941] Chr7:40350383..47034422 [GRCh37]
Chr7:7p14.1-12.3
pathogenic
GRCh37/hg19 7p21.3-12.1(chr7:11048840-52863626)x3 copy number gain See cases [RCV000512091] Chr7:11048840..52863626 [GRCh37]
Chr7:7p21.3-12.1
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Speech-language disorder 1 [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_000598.5(IGFBP3):c.404-8G>A single nucleotide variant not provided [RCV000975150] Chr7:45917447 [GRCh38]
Chr7:45957046 [GRCh37]
Chr7:7p12.3
benign
NM_000598.5(IGFBP3):c.700G>A (p.Gly234Ser) single nucleotide variant not provided [RCV000888729] Chr7:45916598 [GRCh38]
Chr7:45956197 [GRCh37]
Chr7:7p12.3
benign
NM_000598.5(IGFBP3):c.582C>T (p.Ser194=) single nucleotide variant not provided [RCV000911914] Chr7:45917261 [GRCh38]
Chr7:45956860 [GRCh37]
Chr7:7p12.3
benign
GRCh37/hg19 7p12.3(chr7:45895448-46380286)x3 copy number gain not provided [RCV001005947] Chr7:45895448..46380286 [GRCh37]
Chr7:7p12.3
uncertain significance
GRCh37/hg19 7p14.1-12.3(chr7:41124364-47945566) copy number loss Non-syndromic syndactyly [RCV001352654] Chr7:41124364..47945566 [GRCh37]
Chr7:7p14.1-12.3
pathogenic
GRCh37/hg19 7p13-12.2(chr7:43341583-50171623) copy number loss Intracranial hemorrhage [RCV001352658] Chr7:43341583..50171623 [GRCh37]
Chr7:7p13-12.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5472 AgrOrtholog
COSMIC IGFBP3 COSMIC
Ensembl Genes ENSG00000146674 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000275521 UniProtKB/Swiss-Prot
  ENSP00000370473 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000370476 UniProtKB/TrEMBL
  ENSP00000389668 UniProtKB/TrEMBL
  ENSP00000390298 UniProtKB/TrEMBL
  ENSP00000399116 UniProtKB/TrEMBL
  ENSP00000477772 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000480717 UniProtKB/TrEMBL
Ensembl Transcript ENST00000275521 UniProtKB/Swiss-Prot
  ENST00000381083 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000381086 UniProtKB/TrEMBL
  ENST00000417621 UniProtKB/TrEMBL
  ENST00000428530 UniProtKB/TrEMBL
  ENST00000448817 UniProtKB/TrEMBL
  ENST00000613132 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000615754 UniProtKB/TrEMBL
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000146674 GTEx
HGNC ID HGNC:5472 ENTREZGENE
Human Proteome Map IGFBP3 Human Proteome Map
InterPro Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_1-6_chordata UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin_GF-bd_Cys-rich_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 3486 ENTREZGENE
OMIM 146732 OMIM
PANTHER PTHR11551:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IGFBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IGFBP3 RGD, PharmGKB
PRINTS IGFBPFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBPFAMILY3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IGFBP_N_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00121 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57610 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6XND0_HUMAN UniProtKB/TrEMBL
  A6XND1_HUMAN UniProtKB/TrEMBL
  B3KPF0 ENTREZGENE, UniProtKB/TrEMBL
  B3KWK7_HUMAN UniProtKB/TrEMBL
  C9JMX4_HUMAN UniProtKB/TrEMBL
  H0Y485_HUMAN UniProtKB/TrEMBL
  H0Y5K2_HUMAN UniProtKB/TrEMBL
  IBP3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A4D2F5 UniProtKB/Swiss-Prot
  D3DVM0 UniProtKB/Swiss-Prot
  Q2V509 UniProtKB/Swiss-Prot
  Q6P1M6 UniProtKB/Swiss-Prot
  Q9UCL4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-08 IGFBP3  insulin like growth factor binding protein 3    insulin-like growth factor binding protein 3  Symbol and/or name change 5135510 APPROVED
2011-08-16 IGFBP3  insulin-like growth factor binding protein 3  IGFBP3  insulin-like growth factor binding protein 3  Symbol and/or name change 5135510 APPROVED