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Gene: DCXR (dicarbonyl and L-xylulose reductase) Homo sapiens
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Symbol: DCXR
Name: dicarbonyl and L-xylulose reductase
Description: Exhibits L-xylulose reductase (NADP+) activity; identical protein binding activity; and oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Involved in several processes, including glucose metabolic process; protein homotetramerization; and xylulose metabolic process. Localizes to the cytoplasmic microtubule. Implicated in pentosuria.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: carbonyl reductase 2; carbonyl reductase II; DCR; diacetyl/l-xylulose reductase; dicarbonyl/L-xylulose reductase; HCR2; HCRII; human carbonyl reductase 2; KIDCR; kidney dicarbonyl reductase; L-xylulose reductase; P34H; PNTSU; SDR20C1; short chain dehydrogenase/reductase family 20C member 1; short chain dehydrogenase/reductase family 20C, member 1; sperm surface protein P34H; XR
Orthologs:
Mus musculus (house mouse) : Dcxr (dicarbonyl L-xylulose reductase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dcxr (dicarbonyl and L-xylulose reductase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DCXR (dicarbonyl and L-xylulose reductase)
Canis lupus familiaris (dog) : DCXR (dicarbonyl and L-xylulose reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967786 (L-xylulose reductase)
Sus scrofa (pig) : LOC110255927 (L-xylulose reductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381782,035,858 - 82,037,697 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,993,757 - 79,995,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,587,046 - 77,588,862 (-)NCBINCBI36hg18NCBI36
Build 341777,587,045 - 77,588,862NCBI
Celera1776,587,448 - 76,589,264 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1775,393,877 - 75,395,693 (-)NCBIHuRef
CHM1_11780,079,960 - 80,081,776 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on DCXR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733826
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.