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Gene: CYP2B6 (cytochrome P450 family 2 subfamily B member 6) Homo sapiens
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Symbol: CYP2B6
Name: cytochrome P450 family 2 subfamily B member 6
Description: Exhibits heme binding activity and monooxygenase activity. Involved in several processes, including exogenous drug catabolic process; steroid metabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Implicated in acute myeloid leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1,4-cineole 2-exo-monooxygenase; CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; cytochrome P450 2B6; cytochrome P450 IIB1; cytochrome P450, family 2, subfamily B; cytochrome P450, family 2, subfamily B, polypeptide 6; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6; EFVM; IIB1; P450
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1940,991,282 - 41,018,398 (+)EnsemblGRCh38hg38GRCh38
GRCh381940,991,282 - 41,018,398 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371941,497,138 - 41,524,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361946,189,044 - 46,216,141 (+)NCBINCBI36hg18NCBI36
Build 341946,189,043 - 46,216,141NCBI
Celera1938,297,361 - 38,324,463 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1937,929,211 - 37,956,335 (+)NCBIHuRef
CHM1_11941,496,934 - 41,524,020 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CYP2B6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346751
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.