![]() Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | RGD:3836 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PHLDA1 mRNA] | CTD | PMID:31150632 | (-)-demecolcine | increases expression | EXP | | 6480464 | Demecolcine results in increased expression of PHLDA1 mRNA | CTD | PMID:23649840 | 1,1-dichloroethene | increases expression | ISO | RGD:1332326 | 6480464 | vinylidene chloride results in increased expression of PHLDA1 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:3836 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of PHLDA1 mRNA | CTD | PMID:27840820 | 1-chloro-2,4-dinitrobenzene | increases expression | EXP | | 6480464 | Dinitrochlorobenzene results in increased expression of PHLDA1 mRNA | CTD | PMID:17374397 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of PHLDA1 mRNA | CTD | PMID:26865667 | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of PHLDA1 mRNA | CTD | PMID:25321415 | 17beta-estradiol | multiple interactions | ISO | RGD:1332326 | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of PHLDA1 mRNA | CTD | PMID:18556351 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of PHLDA1 mRNA | CTD | PMID:18556351, PMID:20106945 | 17beta-estradiol | increases expression | ISO | RGD:1332326 | 6480464 | Estradiol results in increased expression of PHLDA1 mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of PHLDA1 mRNA, [Estradiol co-treated with TGFB1 protein] results in increased expression of PHLDA1 mRNA | CTD | PMID:20660070, PMID:30165855 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RGD:1332326 | 6480464 | Dihydrotestosterone results in increased expression of PHLDA1 mRNA | CTD | PMID:17023530 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23146750 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PHLDA1 mRNA | CTD | PMID:16704738 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1332326 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHLDA1 mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1332326 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PHLDA1 mRNA | CTD | PMID:15034205 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:3836 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHLDA1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHLDA1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PHLDA1 mRNA | CTD | PMID:21296121 | 2-hydroxypropanoic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PHLDA1 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | EXP | | 6480464 | beta-methylcholine affects the expression of PHLDA1 mRNA | CTD | PMID:21179406 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:19692669 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | RGD:3836 | 6480464 | 3 more ... | CTD | PMID:23196670 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | RGD:1332326 | 6480464 | tetrabromobisphenol A results in increased expression of PHLDA1 mRNA | CTD | PMID:25172293 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:1332326 | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of PHLDA1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1332326 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of PHLDA1 mRNA | CTD | PMID:30951980 | 4-(ethoxymethylene)-2-phenyloxazol-5-one | increases expression | EXP | | 6480464 | Oxazolone results in increased expression of PHLDA1 mRNA | CTD | PMID:17374397 | 4-hydroxynon-2-enal | decreases expression | ISO | RGD:1332326 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of PHLDA1 mRNA | CTD | PMID:19191707 | 5-aza-2'-deoxycytidine | affects expression | EXP | | 6480464 | Decitabine affects the expression of PHLDA1 mRNA | CTD | PMID:17194187, PMID:23300844 | 6-propyl-2-thiouracil | increases expression | ISO | RGD:3836 | 6480464 | Propylthiouracil results in increased expression of PHLDA1 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | RGD:1332326 | 6480464 | Acrylamide results in increased expression of PHLDA1 mRNA | CTD | PMID:30807115 | aflatoxin B1 | affects expression | EXP | | 6480464 | Aflatoxin B1 affects the expression of PHLDA1 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | RGD:3836 | 6480464 | Aflatoxin B1 results in increased expression of PHLDA1 mRNA | CTD | PMID:25378103 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PHLDA1 mRNA | CTD | PMID:22100608, PMID:27153756 | aflatoxin B1 | increases expression | ISO | RGD:1332326 | 6480464 | Aflatoxin B1 results in increased expression of PHLDA1 mRNA | CTD | PMID:19770486 | aldehydo-D-glucose | increases expression | ISO | RGD:1332326 | 6480464 | Glucose results in increased expression of PHLDA1 mRNA | CTD | PMID:17178593 | all-trans-retinoic acid | increases expression | ISO | RGD:1332326 | 6480464 | Tretinoin results in increased expression of PHLDA1 mRNA | CTD | PMID:16604517 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of PHLDA1 mRNA | CTD | PMID:21934132, PMID:23830798 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of PHLDA1 mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | ISO | RGD:3836 | 6480464 | Ammonium Chloride affects the expression of PHLDA1 mRNA | CTD | PMID:16483693 | amphibole asbestos | increases expression | EXP | | 6480464 | Asbestos, Amphibole results in increased expression of PHLDA1 mRNA | CTD | PMID:20831825 | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of PHLDA1 mRNA | CTD | PMID:24449571 | arachidonic acid | increases expression | EXP | | 6480464 | Arachidonic Acid results in increased expression of PHLDA1 mRNA | CTD | PMID:16704987 | arsenous acid | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of PHLDA1 mRNA | CTD | PMID:20458559 | belinostat | increases expression | EXP | | 6480464 | belinostat results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | benzene-1,2,4-triol | increases expression | EXP | | 6480464 | hydroxyhydroquinone results in increased expression of PHLDA1 mRNA | CTD | PMID:17572062 | benzo[a]pyrene | decreases expression | ISO | RGD:1332326 | 6480464 | Benzo(a)pyrene results in decreased expression of PHLDA1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PHLDA1 mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene | increases expression | ISO | RGD:1332326 | 6480464 | Benzo(a)pyrene results in increased expression of PHLDA1 mRNA | CTD | PMID:15034205 more ... | benzo[a]pyrene | multiple interactions | ISO | RGD:1332326 | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of PHLDA1 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene diol epoxide I | increases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[b]fluoranthene | increases expression | ISO | RGD:1332326 | 6480464 | benzo(b)fluoranthene results in increased expression of PHLDA1 mRNA | CTD | PMID:26377693 | benzoates | decreases expression | EXP | | 6480464 | Benzoates analog results in decreased expression of PHLDA1 mRNA | CTD | PMID:29472718 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1332326 | 6480464 | Mustard Gas results in increased expression of PHLDA1 mRNA | CTD | PMID:15674843 | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of PHLDA1 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | ISO | RGD:3836 | 6480464 | bisphenol A affects the expression of PHLDA1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PHLDA1 mRNA | CTD | PMID:29275510 | bortezomib | increases expression | EXP | | 6480464 | Bortezomib results in increased expression of PHLDA1 mRNA | CTD | PMID:20977926 | bromobenzene | increases expression | ISO | RGD:3836 | 6480464 | bromobenzene results in increased expression of PHLDA1 mRNA | CTD | PMID:15976192 | buta-1,3-diene | decreases expression | ISO | RGD:1332326 | 6480464 | 1, 3-butadiene results in decreased expression of PHLDA1 mRNA | CTD | PMID:29038090 | butan-1-ol | multiple interactions | EXP | | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of PHLDA1 mRNA | CTD | PMID:29432896 | cadmium dichloride | decreases expression | ISO | RGD:1332326 | 6480464 | Cadmium Chloride results in decreased expression of PHLDA1 mRNA | CTD | PMID:15501611 | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of PHLDA1 mRNA | CTD | PMID:25979313 | carbon nanotube | affects expression | ISO | RGD:1332326 | 6480464 | Nanotubes, Carbon analog affects the expression of PHLDA1 mRNA | CTD | PMID:25620056 | carbon nanotube | decreases expression | ISO | RGD:1332326 | 6480464 | Nanotubes, Carbon results in decreased expression of PHLDA1 mRNA | CTD | PMID:25620056 | carbon nanotube | increases expression | ISO | RGD:1332326 | 6480464 | Nanotubes, Carbon analog results in increased expression of PHLDA1 mRNA, Nanotubes, Carbon results in increased expression of PHLDA1 mRNA | CTD | PMID:25554681 | carmustine | affects response to substance | EXP | | 6480464 | PHLDA1 mRNA affects the susceptibility to Carmustine | CTD | PMID:16365179 | chloropicrin | decreases expression | EXP | | 6480464 | chloropicrin results in decreased expression of PHLDA1 mRNA | CTD | PMID:26352163 | chromium(6+) | affects expression | ISO | RGD:1332326 | 6480464 | chromium hexavalent ion affects the expression of PHLDA1 mRNA | CTD | PMID:28472532 | ciguatoxin CTX1B | affects expression | ISO | RGD:1332326 | 6480464 | Ciguatoxins affects the expression of PHLDA1 mRNA | CTD | PMID:18353800 | ciprofibrate | decreases expression | ISO | RGD:1332326 | 6480464 | ciprofibrate results in decreased expression of PHLDA1 mRNA | CTD | PMID:12771043 | cisplatin | affects response to substance | EXP | | 6480464 | PHLDA1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | cisplatin | multiple interactions | EXP | | 6480464 | Cisplatin promotes the reaction [jinfukang results in decreased expression of PHLDA1 mRNA], jinfukang promotes the reaction [Cisplatin results in decreased expression of PHLDA1 mRNA] | CTD | PMID:27392435 | cisplatin | affects expression | EXP | | 6480464 | Cisplatin affects the expression of PHLDA1 mRNA | CTD | PMID:23300844 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of PHLDA1 mRNA | CTD | PMID:19561079, PMID:27392435 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of PHLDA1 mRNA | CTD | PMID:21603599 | cisplatin | increases expression | ISO | RGD:1332326 | 6480464 | Cisplatin results in increased expression of PHLDA1 mRNA | CTD | PMID:21151649 | clofibrate | increases expression | ISO | RGD:1332326 | 6480464 | Clofibrate results in increased expression of PHLDA1 mRNA | CTD | PMID:17585979 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of PHLDA1 mRNA | CTD | PMID:19320972 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PHLDA1 mRNA | CTD | PMID:22941251 | copper atom | decreases expression | ISO | RGD:1332326 | 6480464 | Copper results in decreased expression of PHLDA1 mRNA | CTD | PMID:17205981 | copper(0) | decreases expression | ISO | RGD:1332326 | 6480464 | Copper results in decreased expression of PHLDA1 mRNA | CTD | PMID:17205981 | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of PHLDA1 mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos, Crocidolite results in increased expression of PHLDA1 mRNA | CTD | PMID:18687144, PMID:20831825 | crocidolite asbestos | affects expression | EXP | | 6480464 | Asbestos, Crocidolite affects the expression of PHLDA1 mRNA | CTD | PMID:25757056 | cyclosporin A | increases expression | ISO | RGD:1332326 | 6480464 | Cyclosporine results in increased expression of PHLDA1 mRNA | CTD | PMID:23958496 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PHLDA1 mRNA | CTD | PMID:27989131 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of PHLDA1 mRNA | CTD | PMID:20106945, PMID:25562108 | cylindrospermopsin | increases expression | EXP | | 6480464 | cylindrospermopsin results in increased expression of PHLDA1 mRNA | CTD | PMID:24921660 | D-glucose | increases expression | ISO | RGD:1332326 | 6480464 | Glucose results in increased expression of PHLDA1 mRNA | CTD | PMID:17178593 | decabromodiphenyl ether | increases expression | ISO | RGD:3836 | 6480464 | decabromobiphenyl ether results in increased expression of PHLDA1 mRNA | CTD | PMID:23914054 | diarsenic trioxide | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of PHLDA1 mRNA | CTD | PMID:20458559 | diazinon | increases methylation | EXP | | 6480464 | Diazinon results in increased methylation of PHLDA1 gene | CTD | PMID:22964155 | dibutyl phthalate | increases expression | ISO | RGD:1332326 | 6480464 | Dibutyl Phthalate results in increased expression of PHLDA1 mRNA | CTD | PMID:17361019, PMID:21266533 | dichloroacetic acid | decreases expression | ISO | RGD:1332326 | 6480464 | Dichloroacetic Acid results in decreased expression of PHLDA1 mRNA | CTD | PMID:28962523 | diclofenac | decreases expression | ISO | RGD:1332326 | 6480464 | Diclofenac results in decreased expression of PHLDA1 mRNA | CTD | PMID:26934552 | dieldrin | affects expression | ISO | RGD:3836 | 6480464 | Dieldrin affects the expression of PHLDA1 mRNA | CTD | PMID:22546817 | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of PHLDA1 mRNA | CTD | PMID:24236059 | dioxygen | multiple interactions | ISO | RGD:1332326 | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PHLDA1 mRNA | CTD | PMID:30529165 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of PHLDA1 mRNA | CTD | PMID:24383545 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PHLDA1 mRNA | CTD | PMID:29803840 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of PHLDA1 mRNA | CTD | PMID:30031762 | elemental selenium | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PHLDA1 mRNA | CTD | PMID:19244175 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PHLDA1 mRNA | CTD | PMID:26615145 | endosulfan | increases expression | ISO | RGD:3836 | 6480464 | Endosulfan results in increased expression of PHLDA1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | RGD:1332326 | 6480464 | Ethanol affects the splicing of PHLDA1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of PHLDA1 mRNA | CTD | PMID:23649840 | fenofibrate | decreases expression | ISO | RGD:1332326 | 6480464 | Fenofibrate results in decreased expression of PHLDA1 mRNA | CTD | PMID:11798191 | ferric oxide | increases expression | ISO | RGD:1332326 | 6480464 | ferric oxide analog results in increased expression of PHLDA1 mRNA | CTD | PMID:25086211 | ferroheme b | decreases expression | ISO | RGD:1332326 | 6480464 | Heme metabolite results in decreased expression of PHLDA1 mRNA | CTD | PMID:19191707 | fluoranthene | multiple interactions | ISO | RGD:1332326 | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of PHLDA1 mRNA, SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of PHLDA1 mRNA] | CTD | PMID:28329830 | fluoranthene | increases expression | ISO | RGD:1332326 | 6480464 | fluoranthene results in increased expression of PHLDA1 mRNA | CTD | PMID:28329830 | flutamide | increases expression | ISO | RGD:3836 | 6480464 | Flutamide results in increased expression of PHLDA1 mRNA | CTD | PMID:24793618 | fonofos | decreases methylation | EXP | | 6480464 | Fonofos results in decreased methylation of PHLDA1 promoter | CTD | PMID:22847954 | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of PHLDA1 mRNA | CTD | PMID:23416264, PMID:27664576 | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of PHLDA1 mRNA | CTD | PMID:28937961 | fumonisin B1 | decreases expression | ISO | RGD:1332326 | 6480464 | fumonisin B1 results in decreased expression of PHLDA1 mRNA | CTD | PMID:16221962 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of PHLDA1 mRNA | CTD | PMID:22228119, PMID:26865667 | glucose | increases expression | ISO | RGD:1332326 | 6480464 | Glucose results in increased expression of PHLDA1 mRNA | CTD | PMID:17178593 | heme b | decreases expression | ISO | RGD:1332326 | 6480464 | Heme metabolite results in decreased expression of PHLDA1 mRNA | CTD | PMID:19191707 | hexane | decreases methylation | ISO | RGD:3836 | 6480464 | n-hexane results in decreased methylation of PHLDA1 promoter | CTD | PMID:23740543 | hydrogen peroxide | affects expression | EXP | | 6480464 | Hydrogen Peroxide affects the expression of PHLDA1 mRNA | CTD | PMID:20044591 | hydroquinone | increases expression | EXP | | 6480464 | hydroquinone results in increased expression of PHLDA1 mRNA | CTD | PMID:31256213 | irinotecan | decreases expression | EXP | | 6480464 | Irinotecan analog results in decreased expression of PHLDA1 mRNA | CTD | PMID:18927307 | isoflavones | affects expression | EXP | | 6480464 | Isoflavones affects the expression of PHLDA1 mRNA | CTD | PMID:16365062 | isoprenaline | decreases expression | ISO | RGD:1332326 | 6480464 | Isoproterenol results in decreased expression of PHLDA1 mRNA | CTD | PMID:20003209 | isotretinoin | multiple interactions | EXP | | 6480464 | [vorinostat co-treated with Isotretinoin] results in increased expression of PHLDA1 mRNA | CTD | PMID:18769122 | L-ascorbic acid | multiple interactions | EXP | | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA1 mRNA | CTD | PMID:17639512 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of PHLDA1 mRNA | CTD | PMID:28988120 | lipopolysaccharide | increases expression | ISO | RGD:1332326 | 6480464 | Lipopolysaccharides results in increased expression of PHLDA1 mRNA | CTD | PMID:27339419 | manganese(II) chloride | increases expression | ISO | RGD:3836 | 6480464 | manganese chloride results in increased expression of PHLDA1 mRNA | CTD | PMID:28801915 | melphalan | increases expression | EXP | | 6480464 | Melphalan results in increased expression of PHLDA1 mRNA | CTD | PMID:22363485 | menadione | affects expression | EXP | | 6480464 | Vitamin K 3 affects the expression of PHLDA1 mRNA | CTD | PMID:20044591 | mercury dibromide | increases expression | EXP | | 6480464 | mercuric bromide results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of PHLDA1 mRNA | CTD | PMID:23179753 more ... | methylmercury chloride | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | N-nitrosodiethylamine | decreases expression | ISO | RGD:1332326 | 6480464 | Diethylnitrosamine results in decreased expression of PHLDA1 mRNA | CTD | PMID:12771043 | N-nitrosodimethylamine | increases expression | ISO | RGD:3836 | 6480464 | Dimethylnitrosamine results in increased expression of PHLDA1 mRNA | CTD | PMID:15976192 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of PHLDA1 mRNA | CTD | PMID:23195993 | nickel sulfate | increases expression | EXP | | 6480464 | nickel sulfate results in increased expression of PHLDA1 mRNA | CTD | PMID:16780908, PMID:17374397 | Niclosamide | increases expression | EXP | | 6480464 | Niclosamide results in increased expression of PHLDA1 mRNA | CTD | PMID:28284560 | ozone | increases expression | ISO | RGD:1332326 | 6480464 | Ozone results in increased expression of PHLDA1 mRNA | CTD | PMID:17095637 | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | EXP | | 6480464 | panobinostat results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | paracetamol | decreases expression | ISO | RGD:1332326 | 6480464 | Acetaminophen results in decreased expression of PHLDA1 mRNA | CTD | PMID:17585979 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PHLDA1 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PHLDA1 mRNA | CTD | PMID:26690555 | paracetamol | increases expression | ISO | RGD:3836 | 6480464 | Acetaminophen results in increased expression of PHLDA1 mRNA | CTD | PMID:15976192 | paracetamol | affects expression | ISO | RGD:1332326 | 6480464 | Acetaminophen affects the expression of PHLDA1 mRNA | CTD | PMID:17562736 | parathion | decreases methylation | EXP | | 6480464 | Parathion results in decreased methylation of PHLDA1 promoter | CTD | PMID:22847954 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of PHLDA1 mRNA | CTD | PMID:25868421 | phenobarbital | increases expression | ISO | RGD:1332326 | 6480464 | Phenobarbital results in increased expression of PHLDA1 mRNA | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | RGD:1332326 | 6480464 | Phenobarbital affects the expression of PHLDA1 mRNA | CTD | PMID:23091169 | phenobarbital | multiple interactions | ISO | RGD:1332326 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PHLDA1 mRNA] | CTD | PMID:19482888 | phenylephrine | increases expression | ISO | RGD:3836 | 6480464 | Phenylephrine results in increased expression of PHLDA1 mRNA | CTD | PMID:18158353 | phenylmercury acetate | increases expression | EXP | | 6480464 | Phenylmercuric Acetate results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | RGD:1332326 | 6480464 | pirinixic acid results in decreased expression of PHLDA1 mRNA | CTD | PMID:11798191 more ... | progesterone | increases expression | EXP | | 6480464 | Progesterone results in increased expression of PHLDA1 mRNA | CTD | PMID:21795739 | progesterone | multiple interactions | ISO | RGD:1332326 | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of PHLDA1 mRNA | CTD | PMID:18556351 | progesterone | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of PHLDA1 mRNA | CTD | PMID:20660070 | propanal | increases expression | EXP | | 6480464 | propionaldehyde results in increased expression of PHLDA1 mRNA | CTD | PMID:26079696 | quercetin | multiple interactions | EXP | | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA1 mRNA | CTD | PMID:17639512 | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of PHLDA1 mRNA | CTD | PMID:21632981 | rac-lactic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PHLDA1 mRNA | CTD | PMID:30851411 | SB 203580 | multiple interactions | ISO | RGD:1332326 | 6480464 | SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of PHLDA1 mRNA] | CTD | PMID:28329830 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | selenium atom | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PHLDA1 mRNA | CTD | PMID:19244175 | silicon dioxide | increases expression | ISO | RGD:1332326 | 6480464 | Silicon Dioxide results in increased expression of PHLDA1 mRNA | CTD | PMID:19073995 | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of PHLDA1 mRNA | CTD | PMID:26014281 | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of PHLDA1 mRNA | CTD | PMID:26014281 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of PHLDA1 mRNA | CTD | PMID:21281968 | sodium arsenite | affects methylation | EXP | | 6480464 | sodium arsenite affects the methylation of PHLDA1 gene | CTD | PMID:28589171 | sodium dichromate | affects expression | ISO | RGD:3836 | 6480464 | sodium bichromate affects the expression of PHLDA1 mRNA | CTD | PMID:22110744 | sodium dichromate | increases expression | ISO | RGD:1332326 | 6480464 | sodium bichromate results in increased expression of PHLDA1 mRNA | CTD | PMID:27859739 | sodium dichromate | increases expression | ISO | RGD:3836 | 6480464 | sodium bichromate results in increased expression of PHLDA1 mRNA | CTD | PMID:22561333 | succimer | multiple interactions | ISO | RGD:1332326 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of PHLDA1 mRNA | CTD | PMID:21641980 | tacrolimus hydrate | increases expression | ISO | RGD:1332326 | 6480464 | Tacrolimus results in increased expression of PHLDA1 mRNA | CTD | PMID:23958496 | temozolomide | affects response to substance | EXP | | 6480464 | PHLDA1 mRNA affects the susceptibility to temozolomide | CTD | PMID:16365179 | terbufos | decreases methylation | EXP | | 6480464 | terbufos results in decreased methylation of PHLDA1 promoter | CTD | PMID:22847954 | tert-butyl hydroperoxide | increases expression | EXP | | 6480464 | tert-Butylhydroperoxide results in increased expression of PHLDA1 mRNA | CTD | PMID:15336504 | Tesaglitazar | decreases expression | ISO | RGD:3836 | 6480464 | tesaglitazar results in decreased expression of PHLDA1 mRNA | CTD | PMID:21515302 | testosterone | increases expression | ISO | RGD:1332326 | 6480464 | Testosterone results in increased expression of PHLDA1 mRNA | CTD | PMID:21669218 | testosterone enanthate | affects expression | EXP | | 6480464 | testosterone enanthate affects the expression of PHLDA1 mRNA | CTD | PMID:17440010 | tetrachloromethane | increases expression | ISO | RGD:3836 | 6480464 | Carbon Tetrachloride results in increased expression of PHLDA1 mRNA | CTD | PMID:15976192, PMID:31150632 | tetrachloromethane | multiple interactions | ISO | RGD:3836 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PHLDA1 mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | RGD:3836 | 6480464 | Thioacetamide results in increased expression of PHLDA1 mRNA | CTD | PMID:15976192 more ... | titanium dioxide | increases expression | ISO | RGD:1332326 | 6480464 | titanium dioxide results in increased expression of PHLDA1 mRNA | CTD | PMID:27760801 | triacsin C | increases expression | EXP | | 6480464 | triacsin C results in increased expression of PHLDA1 mRNA | CTD | PMID:16704987 | trichloroethene | decreases expression | ISO | RGD:1332326 | 6480464 | Trichloroethylene results in decreased expression of PHLDA1 mRNA | CTD | PMID:25549359 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of PHLDA1 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | trovafloxacin | multiple interactions | ISO | RGD:1332326 | 6480464 | [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PHLDA1 mRNA | CTD | PMID:18930950 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of PHLDA1 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | RGD:1332326 | 6480464 | Valproic Acid results in decreased expression of PHLDA1 mRNA | CTD | PMID:20546886 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of PHLDA1 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of PHLDA1 mRNA | CTD | PMID:25979313 | vinclozolin | affects expression | ISO | RGD:3836 | 6480464 | vinclozolin affects the expression of PHLDA1 mRNA | CTD | PMID:23034163 | vitamin E | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PHLDA1 mRNA | CTD | PMID:19244175 | vorinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:18769122, PMID:27188386 | vorinostat | increases expression | EXP | | 6480464 | vorinostat results in increased expression of PHLDA1 mRNA | CTD | PMID:26272509 | zinc atom | multiple interactions | EXP | | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PHLDA1 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | EXP | | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of PHLDA1 mRNA | CTD | PMID:18593933 | |

Biological Process
Cellular Component
Molecular Function