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Gene: CBX7 (chromobox 7) Homo sapiens
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Symbol: CBX7
Name: chromobox 7
Description: Predicted to have chromatin binding activity; methylated histone binding activity; and single-stranded RNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleus. Implicated in breast cancer; multiple myeloma; and myeloid leukemia. Biomarker of breast carcinoma; carcinoma (multiple); glioblastoma multiforme; stomach cancer (multiple); and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chromobox homolog 7; chromobox protein homolog 7
Orthologs:
Mus musculus (house mouse) : Cbx7 (chromobox 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cbx7 (chromobox 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cbx7 (chromobox 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CBX7 (chromobox 7)
Canis lupus familiaris (dog) : CBX7 (chromobox 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cbx7 (chromobox 7)
Sus scrofa (pig) : CBX7 (chromobox 7)
Chlorocebus sabaeus (African green monkey) : CBX7 (chromobox 7)
Heterocephalus glaber (naked mole-rat) : Cbx7 (chromobox 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2239,120,167 - 39,152,680 (-)EnsemblGRCh38hg38GRCh38
GRCh382239,130,772 - 39,152,680 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,526,777 - 39,548,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,856,723 - 37,878,484 (-)NCBINCBI36hg18NCBI36
Build 342237,851,280 - 37,873,038NCBI
Celera2223,328,820 - 23,350,581 (-)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2222,493,890 - 22,515,575 (-)NCBIHuRef
CHM1_12239,485,611 - 39,507,403 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CBX7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353483
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.