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Gene: MMP13 (matrix metallopeptidase 13) Homo sapiens
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Symbol: MMP13
Name: matrix metallopeptidase 13
RGD ID: 1343267
Description: Exhibits collagen binding activity; metal ion binding activity; and metalloendopeptidase activity. Involved in bone morphogenesis; collagen catabolic process; and extracellular matrix disassembly. Predicted to localize to extracellular space. Implicated in anodontia; artery disease (multiple); bone disease (multiple); and ovarian carcinoma. Biomarker of invasive ductal carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLG3; collagenase 3; MANDP1; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); MDST; MMP-13
Orthologs:
Mus musculus (house mouse) : Mmp13 (matrix metallopeptidase 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mmp13 (matrix metallopeptidase 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp13 (matrix metallopeptidase 13)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP13 (matrix metallopeptidase 13)
Canis lupus familiaris (dog) : MMP13 (matrix metallopeptidase 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp13 (matrix metallopeptidase 13)
Sus scrofa (pig) : MMP13 (matrix metallopeptidase 13)
Chlorocebus sabaeus (African green monkey) : MMP13 (matrix metallopeptidase 13)
Heterocephalus glaber (naked mole-rat) : Mmp13 (matrix metallopeptidase 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11102,942,995 - 102,955,732 (-)EnsemblGRCh38hg38GRCh38
GRCh3811102,942,995 - 102,955,732 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,813,721 - 102,826,463 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,318,934 - 102,331,672 (-)NCBINCBI36hg18NCBI36
Build 3411102,318,933 - 102,331,672NCBI
Celera1199,975,301 - 99,988,043 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,741,671 - 98,754,423 (-)NCBIHuRef
CHM1_111102,696,655 - 102,709,340 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MMP13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343267
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.