COPG1 (COPI coat complex subunit gamma 1) - Rat Genome Database

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Gene: COPG1 (COPI coat complex subunit gamma 1) Homo sapiens
Analyze
Symbol: COPG1
Name: COPI coat complex subunit gamma 1
RGD ID: 1345265
HGNC Page HGNC:2236
Description: Predicted to enable structural molecule activity. Predicted to be involved in several processes, including Golgi vesicle transport; establishment of Golgi localization; and organelle transport along microtubule. Located in Golgi apparatus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: coat protein gamma-cop; coatomer protein complex subunit gamma 1; coatomer protein complex, subunit gamma; coatomer protein complex, subunit gamma 1; coatomer subunit gamma; coatomer subunit gamma-1; COPG; FLJ21068; gamma-1-coat protein; gamma-1-COP; gamma-coat protein; gamma-COP
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383129,249,606 - 129,277,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3129,249,606 - 129,277,773 (+)EnsemblGRCh38hg38GRCh38
GRCh373128,968,449 - 128,996,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,451,143 - 130,479,306 (+)NCBINCBI36Build 36hg18NCBI36
Build 343130,451,150 - 130,479,312NCBI
Celera3127,399,234 - 127,427,322 (+)NCBICelera
Cytogenetic Map3q21.3NCBI
HuRef3126,353,590 - 126,381,662 (+)NCBIHuRef
CHM1_13128,931,675 - 128,959,852 (+)NCBICHM1_1
T2T-CHM13v2.03131,994,406 - 132,022,572 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8533093   PMID:8599108   PMID:8858162   PMID:8940050   PMID:9482852   PMID:9751720   PMID:10720466   PMID:10921873   PMID:10931946   PMID:10982407   PMID:11018518   PMID:11031247  
PMID:11056392   PMID:11884415   PMID:11893085   PMID:12134073   PMID:12388752   PMID:12477932   PMID:14527956   PMID:14690497   PMID:14702039   PMID:14729954   PMID:15489334   PMID:16956762  
PMID:17148452   PMID:17314511   PMID:17353931   PMID:18029348   PMID:19039328   PMID:19615732   PMID:19738201   PMID:20360068   PMID:20467437   PMID:20468064   PMID:20562859   PMID:21873635  
PMID:21900206   PMID:21988832   PMID:22586326   PMID:22863883   PMID:22939629   PMID:23402259   PMID:23403292   PMID:23427261   PMID:24457600   PMID:25036637   PMID:25147182   PMID:25476789  
PMID:25609649   PMID:25921289   PMID:25963833   PMID:26186194   PMID:26344197   PMID:26472760   PMID:26496610   PMID:26508657   PMID:26511642   PMID:26618866   PMID:26638075   PMID:26673895  
PMID:26687479   PMID:26831064   PMID:26972000   PMID:27342126   PMID:27377895   PMID:27578003   PMID:27621311   PMID:27926873   PMID:28378594   PMID:28514442   PMID:28515276   PMID:28581483  
PMID:28646128   PMID:28675297   PMID:28685749   PMID:28712289   PMID:28973437   PMID:29128334   PMID:29467282   PMID:29507755   PMID:29509190   PMID:29568061   PMID:29676528   PMID:29955894  
PMID:30258100   PMID:30352685   PMID:30462309   PMID:30463901   PMID:30567983   PMID:30575818   PMID:30631079   PMID:30711629   PMID:30833792   PMID:30948266   PMID:31067453   PMID:31073040  
PMID:31091453   PMID:31240132   PMID:31332168   PMID:31478661   PMID:31586073   PMID:31594818   PMID:31620119   PMID:31678930   PMID:31732153   PMID:31871319   PMID:32149426   PMID:32176628  
PMID:32203420   PMID:32322062   PMID:32521226   PMID:32571874   PMID:32687490   PMID:32786267   PMID:32807901   PMID:32929329   PMID:32941674   PMID:32989298   PMID:33022573   PMID:33060197  
PMID:33239621   PMID:33529166   PMID:33545068   PMID:33644029   PMID:33658012   PMID:33742100   PMID:33766124   PMID:33961781   PMID:34079125   PMID:34473204   PMID:34591877   PMID:34917906  
PMID:35241646   PMID:35256949   PMID:35271311   PMID:35384245   PMID:35446349   PMID:35509820   PMID:35559673   PMID:35562734   PMID:35563538   PMID:35676659   PMID:35687106   PMID:35831314  
PMID:35844135   PMID:35944360   PMID:36168627   PMID:36168628   PMID:36180891   PMID:36215168   PMID:36232890   PMID:36244648   PMID:36282215  


Genomics

Comparative Map Data
COPG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383129,249,606 - 129,277,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3129,249,606 - 129,277,773 (+)EnsemblGRCh38hg38GRCh38
GRCh373128,968,449 - 128,996,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,451,143 - 130,479,306 (+)NCBINCBI36Build 36hg18NCBI36
Build 343130,451,150 - 130,479,312NCBI
Celera3127,399,234 - 127,427,322 (+)NCBICelera
Cytogenetic Map3q21.3NCBI
HuRef3126,353,590 - 126,381,662 (+)NCBIHuRef
CHM1_13128,931,675 - 128,959,852 (+)NCBICHM1_1
T2T-CHM13v2.03131,994,406 - 132,022,572 (+)NCBIT2T-CHM13v2.0
Copg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,864,801 - 87,890,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl687,864,796 - 87,890,577 (+)EnsemblGRCm39 Ensembl
GRCm38687,887,819 - 87,913,595 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,887,814 - 87,913,595 (+)EnsemblGRCm38mm10GRCm38
MGSCv37687,837,934 - 87,863,589 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36687,853,581 - 87,879,236 (+)NCBIMGSCv36mm8
Celera689,824,999 - 89,850,681 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map639.13NCBI
Copg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24120,366,540 - 120,392,502 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4120,366,542 - 120,415,616 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4125,839,212 - 125,863,727 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04121,613,989 - 121,638,505 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04120,238,238 - 120,262,752 (+)NCBIRnor_WKY
Rnor_6.04119,815,041 - 119,840,997 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4119,815,139 - 119,864,114 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04185,062,623 - 185,088,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,109,613 - 122,134,049 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4109,326,188 - 109,350,625 (+)NCBICelera
Cytogenetic Map4q34NCBI
Copg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542913,578,494 - 13,616,463 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542913,582,676 - 13,615,801 (+)NCBIChiLan1.0ChiLan1.0
COPG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan13127,190,069 - 127,218,271 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03126,310,558 - 126,338,726 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13133,664,856 - 133,693,633 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3133,664,856 - 133,694,849 (+)Ensemblpanpan1.1panPan2
COPG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1202,832,150 - 2,860,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl202,832,198 - 2,860,320 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha202,869,065 - 2,897,262 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0202,852,770 - 2,880,977 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl202,844,919 - 2,880,996 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1202,572,649 - 2,600,856 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0202,895,653 - 2,923,949 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0202,860,084 - 2,888,263 (-)NCBIUU_Cfam_GSD_1.0
Copg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494220,196,871 - 20,218,086 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936798238,571 - 260,083 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936798238,741 - 259,962 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1371,672,733 - 71,730,399 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11371,707,097 - 71,730,402 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21379,410,094 - 79,420,841 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COPG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12251,787,002 - 51,812,031 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2251,787,340 - 51,812,026 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041114,585,201 - 114,613,333 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Copg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624872299,625 - 320,974 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in COPG1
31 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29		 pathogenic
GRCh38/hg38 3q21.3-23(chr3:126106779-140918089)x3 copy number gain See cases [RCV000142010] Chr3:126106779..140918089 [GRCh38]
Chr3:125825622..140636931 [GRCh37]
Chr3:127308312..142119621 [NCBI36]
Chr3:3q21.3-23		 uncertain significance
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24		 pathogenic
GRCh38/hg38 3q21.3-22.1(chr3:127607945-133566661)x1 copy number loss See cases [RCV000142787] Chr3:127607945..133566661 [GRCh38]
Chr3:127326788..133285505 [GRCh37]
Chr3:128809478..134768195 [NCBI36]
Chr3:3q21.3-22.1		 likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q21.3-22.1(chr3:128660985-129811200)x1 copy number loss not provided [RCV000682304] Chr3:128660985..129811200 [GRCh37]
Chr3:3q21.3-22.1		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_016128.4(COPG1):c.861G>A (p.Pro287=) single nucleotide variant not provided [RCV000972391] Chr3:129257850 [GRCh38]
Chr3:128976693 [GRCh37]
Chr3:3q21.3		 benign
NM_016128.4(COPG1):c.276C>T (p.Ile92=) single nucleotide variant not provided [RCV000881002] Chr3:129252908 [GRCh38]
Chr3:128971751 [GRCh37]
Chr3:3q21.3		 benign
NC_000003.12:g.(?_129170453)_(129551340_?)dup duplication not provided [RCV001031235] Chr3:128889296..129270183 [GRCh37]
Chr3:3q21.3-22.1		 uncertain significance
NM_016128.4(COPG1):c.1774+7C>T single nucleotide variant not provided [RCV001093175] Chr3:129268627 [GRCh38]
Chr3:128987470 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2526G>T (p.Val842=) single nucleotide variant not provided [RCV001093176] Chr3:129277325 [GRCh38]
Chr3:128996168 [GRCh37]
Chr3:3q21.3		 uncertain significance
NC_000003.11:g.(?_126707437)_(130720194_?)dup duplication Deafness-lymphedema-leukemia syndrome [RCV003113323]|not provided [RCV003107782] Chr3:126707437..130720194 [GRCh37]
Chr3:3q21.3-22.1		 uncertain significance
Single allele deletion Deafness-lymphedema-leukemia syndrome [RCV001541925] Chr3:127966423..136853218 [GRCh37]
Chr3:3q21.3-22.3		 pathogenic
Single allele deletion Deafness-lymphedema-leukemia syndrome [RCV001541926] Chr3:123000000..129700000 [GRCh37]
Chr3:3q21.1-22.1		 pathogenic
NC_000003.11:g.(?_120365818)_(133465047_?)del deletion Alkaptonuria [RCV002035459] Chr3:120365818..133465047 [GRCh37]
Chr3:3q13.33-22.1		 pathogenic
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3 copy number gain not provided [RCV002472621] Chr3:116620308..172042292 [GRCh37]
Chr3:3q13.31-26.31		 pathogenic
NM_016128.4(COPG1):c.1751C>T (p.Ala584Val) single nucleotide variant Inborn genetic diseases [RCV002945886] Chr3:129268597 [GRCh38]
Chr3:128987440 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.1870C>T (p.Arg624Cys) single nucleotide variant Inborn genetic diseases [RCV002754489] Chr3:129271793 [GRCh38]
Chr3:128990636 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.191C>T (p.Thr64Met) single nucleotide variant Inborn genetic diseases [RCV002968262] Chr3:129252642 [GRCh38]
Chr3:128971485 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2255T>C (p.Val752Ala) single nucleotide variant Inborn genetic diseases [RCV002728421] Chr3:129272903 [GRCh38]
Chr3:128991746 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.1553T>C (p.Met518Thr) single nucleotide variant Inborn genetic diseases [RCV002691336] Chr3:129267945 [GRCh38]
Chr3:128986788 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2317G>A (p.Glu773Lys) single nucleotide variant Inborn genetic diseases [RCV002868928] Chr3:129274898 [GRCh38]
Chr3:128993741 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.112C>T (p.Pro38Ser) single nucleotide variant Inborn genetic diseases [RCV002823556] Chr3:129252302 [GRCh38]
Chr3:128971145 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.1759G>A (p.Ala587Thr) single nucleotide variant Inborn genetic diseases [RCV002949879] Chr3:129268605 [GRCh38]
Chr3:128987448 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.922G>A (p.Val308Ile) single nucleotide variant Inborn genetic diseases [RCV002929389] Chr3:129260383 [GRCh38]
Chr3:128979226 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2434C>G (p.Pro812Ala) single nucleotide variant Inborn genetic diseases [RCV002826123] Chr3:129275232 [GRCh38]
Chr3:128994075 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2459C>T (p.Pro820Leu) single nucleotide variant Inborn genetic diseases [RCV003004406] Chr3:129275257 [GRCh38]
Chr3:128994100 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2355G>T (p.Lys785Asn) single nucleotide variant Inborn genetic diseases [RCV002645345] Chr3:129274936 [GRCh38]
Chr3:128993779 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.272C>T (p.Thr91Ile) single nucleotide variant Inborn genetic diseases [RCV002931660] Chr3:129252904 [GRCh38]
Chr3:128971747 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2263G>C (p.Asp755His) single nucleotide variant Inborn genetic diseases [RCV002804651] Chr3:129274844 [GRCh38]
Chr3:128993687 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.901G>T (p.Ala301Ser) single nucleotide variant Inborn genetic diseases [RCV002964150] Chr3:129260362 [GRCh38]
Chr3:128979205 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2527C>T (p.Arg843Cys) single nucleotide variant Inborn genetic diseases [RCV002936533] Chr3:129277326 [GRCh38]
Chr3:128996169 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2402T>C (p.Val801Ala) single nucleotide variant Inborn genetic diseases [RCV002854995] Chr3:129275200 [GRCh38]
Chr3:128994043 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.1931C>T (p.Thr644Met) single nucleotide variant Inborn genetic diseases [RCV002965321] Chr3:129271854 [GRCh38]
Chr3:128990697 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2087G>A (p.Arg696Gln) single nucleotide variant Inborn genetic diseases [RCV003215014] Chr3:129272344 [GRCh38]
Chr3:128991187 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.401G>T (p.Ser134Ile) single nucleotide variant Inborn genetic diseases [RCV003220353] Chr3:129254986 [GRCh38]
Chr3:128973829 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.1885C>T (p.Leu629Phe) single nucleotide variant Inborn genetic diseases [RCV003193376] Chr3:129271808 [GRCh38]
Chr3:128990651 [GRCh37]
Chr3:3q21.3		 uncertain significance
NM_016128.4(COPG1):c.2584G>A (p.Glu862Lys) single nucleotide variant Inborn genetic diseases [RCV003191964] Chr3:129277383 [GRCh38]
Chr3:128996226 [GRCh37]
Chr3:3q21.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2139
Count of miRNA genes:966
Interacting mature miRNAs:1143
Transcripts:ENST00000314797, ENST00000504350, ENST00000504547, ENST00000509208, ENST00000509889, ENST00000512034, ENST00000513410, ENST00000513965, ENST00000514478, ENST00000515725
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH98834  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373128,996,304 - 128,996,434UniSTSGRCh37
Build 363130,478,994 - 130,479,124RGDNCBI36
Celera3127,427,009 - 127,427,139RGD
Cytogenetic Map3q21.3UniSTS
HuRef3126,381,350 - 126,381,480UniSTS
GeneMap99-GB4 RH Map3458.7UniSTS
HSC2JD062  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373128,996,418 - 128,996,594UniSTSGRCh37
Build 363130,479,108 - 130,479,284RGDNCBI36
Celera3127,427,123 - 127,427,300RGD
Cytogenetic Map3q21.3UniSTS
HuRef3126,381,464 - 126,381,640UniSTS
GeneMap99-GB4 RH Map3458.7UniSTS
Whitehead-RH Map3552.0UniSTS
DBEST27818  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373128,996,469 - 128,996,581UniSTSGRCh37
Build 363130,479,159 - 130,479,271RGDNCBI36
Celera3127,427,175 - 127,427,287RGD
Cytogenetic Map3q21.3UniSTS
HuRef3126,381,515 - 126,381,627UniSTS
Stanford-G3 RH Map35787.0UniSTS
NCBI RH Map31140.6UniSTS
GeneMap99-G3 RH Map36257.0UniSTS
D3S3816  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373128,996,352 - 128,996,588UniSTSGRCh37
Build 363130,479,042 - 130,479,278RGDNCBI36
Celera3127,427,057 - 127,427,294RGD
Cytogenetic Map3q21.3UniSTS
HuRef3126,381,398 - 126,381,634UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 3
Medium 2439 2903 1724 622 1923 463 4357 2138 3620 419 1457 1613 175 1 1204 2788 6 2
Low 88 2 2 28 2 59 114
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000314797   ⟹   ENSP00000325002
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,249,606 - 129,277,773 (+)Ensembl
RefSeq Acc Id: ENST00000504350   ⟹   ENSP00000426457
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,249,653 - 129,255,040 (+)Ensembl
RefSeq Acc Id: ENST00000504547
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,260,227 - 129,265,675 (+)Ensembl
RefSeq Acc Id: ENST00000509208
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,254,327 - 129,255,039 (+)Ensembl
RefSeq Acc Id: ENST00000509889   ⟹   ENSP00000422478
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,265,752 - 129,277,457 (+)Ensembl
RefSeq Acc Id: ENST00000512034
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,272,853 - 129,275,183 (+)Ensembl
RefSeq Acc Id: ENST00000513410
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,263,911 - 129,267,235 (+)Ensembl
RefSeq Acc Id: ENST00000513965
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,249,627 - 129,253,098 (+)Ensembl
RefSeq Acc Id: ENST00000514478   ⟹   ENSP00000420916
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,272,296 - 129,277,498 (+)Ensembl
RefSeq Acc Id: ENST00000515725
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3129,249,632 - 129,277,771 (+)Ensembl
RefSeq Acc Id: NM_016128   ⟹   NP_057212
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383129,249,606 - 129,277,773 (+)NCBI
GRCh373128,968,453 - 128,996,616 (+)ENTREZGENE
Build 363130,451,143 - 130,479,306 (+)NCBI Archive
HuRef3126,353,590 - 126,381,662 (+)ENTREZGENE
CHM1_13128,931,675 - 128,959,852 (+)NCBI
T2T-CHM13v2.03131,994,406 - 132,022,572 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_057212   ⟸   NM_016128
- UniProtKB: Q54AC4 (UniProtKB/Swiss-Prot),   Q9Y678 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000426457   ⟸   ENST00000504350
RefSeq Acc Id: ENSP00000422478   ⟸   ENST00000509889
RefSeq Acc Id: ENSP00000325002   ⟸   ENST00000314797
RefSeq Acc Id: ENSP00000420916   ⟸   ENST00000514478
Protein Domains
Coatomer gamma subunit appendage Ig-like subdomain   Coatomer subunit gamma C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y678-F1-model_v2 AlphaFold Q9Y678 1-874 view protein structure

Promoters
RGD ID:6865632
Promoter ID:EPDNEW_H5981
Type:initiation region
Name:COPG1_1
Description:coatomer protein complex subunit gamma 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383129,249,606 - 129,249,666EPDNEW
RGD ID:6800806
Promoter ID:HG_KWN:46166
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_016128,   UC010HTB.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363130,450,889 - 130,451,389 (+)MPROMDB
RGD ID:6812282
Promoter ID:HG_ACW:55904
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:COPG.GAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 363130,474,106 - 130,474,606 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:2236 AgrOrtholog
COSMIC COPG1 COSMIC
Ensembl Genes ENSG00000181789 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000325002 ENTREZGENE
  ENSP00000325002.6 UniProtKB/Swiss-Prot
  ENSP00000420916.1 UniProtKB/TrEMBL
  ENSP00000422478.1 UniProtKB/TrEMBL
  ENSP00000426457.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000314797 ENTREZGENE
  ENST00000314797.10 UniProtKB/Swiss-Prot
  ENST00000504350.1 UniProtKB/TrEMBL
  ENST00000509889.5 UniProtKB/TrEMBL
  ENST00000514478.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot
  2.60.40.1480 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.310.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000181789 GTEx
HGNC ID HGNC:2236 ENTREZGENE
Human Proteome Map COPG1 Human Proteome Map
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  Clathrin/coatomer_adapt-like_N UniProtKB/Swiss-Prot
  Clathrin_app_Ig-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer/calthrin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer_g_Cpla UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer_gsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer_gsu_app_Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer_gsu_app_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:22820 UniProtKB/Swiss-Prot
NCBI Gene 22820 ENTREZGENE
OMIM 615525 OMIM
PANTHER COATOMER SUBUNIT GAMMA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10261 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/Swiss-Prot
  Coatomer_g_Cpla UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COP-gamma_platf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26752 PharmGKB
PIRSF Coatomer_gamma_subunit UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
  SSF49348 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55711 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt COPG1_HUMAN UniProtKB/Swiss-Prot
  D6RG17_HUMAN UniProtKB/TrEMBL
  H0Y8G2_HUMAN UniProtKB/TrEMBL
  H0Y8X7_HUMAN UniProtKB/TrEMBL
  Q54AC4 ENTREZGENE
  Q9Y678 ENTREZGENE
UniProt Secondary A8K6M8 UniProtKB/Swiss-Prot
  B3KMF6 UniProtKB/Swiss-Prot
  Q54AC4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-08 COPG1  COPI coat complex subunit gamma 1  COPG1  coatomer protein complex subunit gamma 1  Symbol and/or name change 5135510 APPROVED
2015-11-17 COPG1  coatomer protein complex subunit gamma 1    coatomer protein complex, subunit gamma 1  Symbol and/or name change 5135510 APPROVED
2012-03-01 COPG1  coatomer protein complex, subunit gamma 1  COPG  coatomer protein complex, subunit gamma  Symbol and/or name change 5135510 APPROVED