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Gene: RANGAP1 (Ran GTPase activating protein 1) Homo sapiens
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Symbol: RANGAP1
Name: Ran GTPase activating protein 1
Description: Exhibits GTPase activator activity; RNA binding activity; and Ran GTPase binding activity. Involved in activation of GTPase activity and negative regulation of protein export from nucleus. Localizes to several cellular components, including aggresome; nuclear membrane; and perinuclear region of cytoplasm. Colocalizes with kinetochore.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Fug1; KIAA1835; MGC20266; ran GTPase-activating protein 1; RANGAP; SD; segregation distorter homolog; segregation distortion; segregation distortion (Drosophila)
Orthologs:
Mus musculus (house mouse) : Rangap1 (RAN GTPase activating protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rangap1 (RAN GTPase activating protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rangap1 (Ran GTPase activating protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RANGAP1 (Ran GTPase activating protein 1)
Canis lupus familiaris (dog) : RANGAP1 (Ran GTPase activating protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rangap1 (Ran GTPase activating protein 1)
Sus scrofa (pig) : RANGAP1 (Ran GTPase activating protein 1)
Chlorocebus sabaeus (African green monkey) : RANGAP1 (Ran GTPase activating protein 1)
Heterocephalus glaber (naked mole-rat) : Rangap1 (Ran GTPase activating protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,245,611 - 41,286,251 (-)EnsemblGRCh38hg38GRCh38
GRCh382241,244,779 - 41,302,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,640,781 - 41,682,255 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,971,561 - 40,012,162 (-)NCBINCBI36hg18NCBI36
Build 342239,966,115 - 40,006,716NCBI
Celera2225,447,987 - 25,488,613 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,605,244 - 24,646,120 (-)NCBIHuRef
CHM1_12241,600,469 - 41,658,135 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RANGAP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321254
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.