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Gene: TFB2M (transcription factor B2, mitochondrial) Homo sapiens
Symbol: TFB2M
Name: transcription factor B2, mitochondrial
RGD ID: 1316077
Description: Exhibits mitochondrial sequence-specific DNA-binding transcription factor activity. Involved in transcription initiation from mitochondrial promoter. Localizes to mitochondrial nucleoid; INTERACTS WITH 2,6-di-tert-butyl-4-methylphenol; all-trans-retinoic acid; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; h-mtTFB; h-mtTFB2; HCV NS5A-transactivated protein 5; hepatitis C virus NS5A-transactivated protein 5; Hkp1; hTFB2M; mitochondrial 12S rRNA dimethylase 2; mitochondrial transcription factor B2; mtTFB2; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2
Mus musculus (house mouse) : Tfb2m (transcription factor B2, mitochondrial)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tfb2m (transcription factor B2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfb2m (transcription factor B2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : TFB2M (transcription factor B2, mitochondrial)
Canis lupus familiaris (dog) : TFB2M (transcription factor B2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfb2m (transcription factor B2, mitochondrial)
Sus scrofa (pig) : TFB2M (transcription factor B2, mitochondrial)
Chlorocebus sabaeus (African green monkey) : TFB2M (transcription factor B2, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Tfb2m (transcription factor B2, mitochondrial)
more info ...
Related Pseudogenes: AL139094.1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1246,540,561 - 246,566,261 (-)EnsemblGRCh38hg38GRCh38
GRCh381246,540,561 - 246,566,261 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371246,703,863 - 246,729,565 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361244,770,489 - 244,796,186 (-)NCBINCBI36hg18NCBI36
Build 341243,029,908 - 243,055,604NCBI
Celera1219,991,213 - 220,016,913 (-)NCBI
Cytogenetic Map1q44NCBI
HuRef1217,089,659 - 217,115,356 (-)NCBIHuRef
CHM1_11247,976,165 - 248,001,862 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TFB2M
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316077
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.