TNFRSF1A (TNF receptor superfamily member 1A) - Rat Genome Database

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Gene: TNFRSF1A (TNF receptor superfamily member 1A) Homo sapiens
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Symbol: TNFRSF1A
Name: TNF receptor superfamily member 1A
RGD ID: 737288
HGNC Page HGNC:11916
Description: Enables tumor necrosis factor binding activity. Involved in several processes, including cellular response to mechanical stimulus; positive regulation of nitrogen compound metabolic process; and tumor necrosis factor-mediated signaling pathway. Located in Golgi membrane; extracellular space; and membrane raft. Part of receptor complex. Implicated in several diseases, including IgA glomerulonephritis; acne; allergic bronchopulmonary aspergillosis; autoimmune disease (multiple); and autosomal dominant familial periodic fever. Biomarker of several diseases, including acquired immunodeficiency syndrome; autoimmune disease (multiple); female reproductive organ cancer (multiple); kidney disease (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD120a; FPF; MGC19588; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R1; TNF-R55; TNF-RI; TNFAR; TNFR-I; TNFR1; TNFR1-d2; TNFR55; TNFR60; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,328,771 - 6,342,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl126,328,757 - 6,342,114 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,437,937 - 6,451,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,308,184 - 6,321,522 (-)NCBINCBI36Build 36hg18NCBI36
Build 34126,308,184 - 6,321,522NCBI
Celera128,054,567 - 8,067,927 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,291,179 - 6,304,533 (-)NCBIHuRef
CHM1_1126,437,153 - 6,450,509 (-)NCBICHM1_1
T2T-CHM13v2.0126,338,163 - 6,351,461 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acne  (IAGP)
acquired immunodeficiency syndrome  (IEP)
Acute Experimental Pancreatitis  (ISO)
acute kidney failure  (IEP,ISO)
adult respiratory distress syndrome  (IEP,ISO)
allergic bronchopulmonary aspergillosis  (IAGP)
allergic disease  (EXP)
Alzheimer's disease  (IEP,ISO)
amyloidosis  (IEP)
anemia  (IEP)
Anorexia  (EXP)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (IEP)
arteriosclerosis  (ISO)
asthma  (ISO)
autoimmune disease  (EXP)
autosomal dominant familial periodic fever  (IAGP)
autosomal recessive pseudohypoaldosteronism type 1  (IAGP)
bacterial pneumonia  (ISO)
Behcet's disease  (IAGP,IEP)
Brain Injuries  (EXP,ISO)
brain ischemia  (EXP,ISO)
bronchiectasis  (IAGP)
bronchiectasis 1  (IAGP)
Cachexia  (EXP,ISO)
CHARGE syndrome  (IAGP)
Chronic Hepatitis C  (IEP)
chronic obstructive pulmonary disease  (IEP)
colon carcinoma  (IEP)
colorectal adenoma  (IEP)
congestive heart failure  (EXP)
coronary artery disease  (IEP)
COVID-19  (IAGP)
Crohn's disease  (ISO)
cryptogenic organizing pneumonia  (IEP)
cystic fibrosis  (EXP)
cytomegalovirus retinitis  (ISO)
Diabetic Nephropathies  (IEP)
End Stage Liver Disease  (ISO)
end stage renal disease  (IEP)
endometrial cancer  (IEP)
Enterovirus Infections  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (EXP,ISO)
extrinsic allergic alveolitis  (IEP)
familial Mediterranean fever  (IAGP)
Febrile Seizures  (IAGP)
Fever  (EXP,IAGP)
fibrosarcoma  (IMP)
focal segmental glomerulosclerosis  (ISO)
genetic disease  (IAGP)
glomerulonephritis  (IEP)
Human Influenza  (IEP,ISO)
Hyperalgesia  (ISO)
Hyperoxia  (EXP)
Hyperphosphatemic Familial Tumoral Calcinosis 1  (IAGP)
IgA glomerulonephritis  (IDA,IEP)
Insulin Resistance  (IEP)
ischemia  (ISO)
kidney disease  (IEP)
Kidney Reperfusion Injury  (ISO)
Legionnaires' disease  (ISO)
Liver Reperfusion Injury  (ISO)
Lung Injury  (EXP)
lung non-small cell carcinoma  (IAGP,IEP)
lupus nephritis  (IEP,ISO)
Metabolic Syndrome  (IAGP)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (EXP,IAGP)
Muscle Weakness  (ISO)
myocardial infarction  (ISO)
Nasal Polyps  (IEP)
Nematode Infections  (ISO)
Neurogenic Inflammation  (ISO)
obesity  (IEP)
obstructive sleep apnea  (IEP)
Optic Nerve Injuries  (ISO)
ovarian cancer  (IEP)
Pain  (ISO)
peroxisome biogenesis disorder 2B  (IAGP)
pneumonia  (EXP)
polymyositis  (IEP)
primary biliary cholangitis  (EXP)
Pseudomonas Infections  (ISO)
psoriasis  (IEP)
Radiation Pneumonitis  (ISO)
renal cell carcinoma  (IEP)
renal fibrosis  (ISO)
Reperfusion Injury  (ISO)
retinal detachment  (ISO)
rheumatoid arthritis  (IAGP)
root resorption  (ISO)
sciatic neuropathy  (ISO)
silicosis  (ISO)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
systemic lupus erythematosus  (IEP)
Temtamy syndrome  (IAGP)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (EXP,ISO)
ureteral obstruction  (ISO)
uveitis  (IDA,IEP,ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(-)-citrinin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1'-acetoxychavicol acetate  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-methylcholine  (EXP)
2-naphthylamine  (EXP)
3,3'-diindolylmethane  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-tert-butylphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (EXP)
[des-Arg(9)]-bradykinin  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
acrolein  (EXP)
AH23848  (EXP)
AICA ribonucleotide  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (EXP,ISO)
Aloe emodin  (EXP)
alpha-naphthoflavone  (EXP)
alpha-pinene  (EXP)
aminoguanidine  (ISO)
amphetamine  (ISO)
amphibole asbestos  (EXP)
antirheumatic drug  (EXP)
arachidonic acid  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
asbestos  (EXP)
asperentin  (ISO)
atorvastatin calcium  (EXP)
azathioprine  (EXP)
Bandrowski's base  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (ISO)
Beta-Solamarine  (EXP)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
boric acid  (ISO)
butylated hydroxyanisole  (ISO)
Butylparaben  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
cannabidiol  (EXP)
capsaicin  (EXP,ISO)
capsazepine  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carbonyl sulfide  (ISO)
cefaloridine  (ISO)
CGP 52608  (EXP)
chloroform  (ISO)
chloroquine  (ISO)
cholesterol  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
curcumin  (EXP)
cyclosporin A  (EXP)
DDT  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP)
diazinon  (EXP)
dibutyl phthalate  (ISO)
diclofenac  (EXP,ISO)
dieldrin  (ISO)
dihydroxyacetone  (EXP)
dimethyl sulfoxide  (EXP)
dimethylarsinic acid  (ISO)
dioscin  (EXP)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP)
epoxiconazole  (ISO)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (EXP)
etoposide  (ISO)
fenamidone  (ISO)
fenthion  (ISO)
flutamide  (ISO)
folic acid  (ISO)
fumonisin B1  (ISO)
furosemide  (ISO)
gadolinium trichloride  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (ISO)
glyphosate  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
hexachlorobenzene  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP)
indometacin  (EXP,ISO)
irinotecan  (ISO)
isoflurane  (ISO)
isoprenaline  (EXP,ISO)
ketoconazole  (ISO)
L-mimosine  (EXP)
lead nitrate  (ISO)
leflunomide  (EXP)
lenalidomide  (EXP)
lignan  (EXP)
lipopolysaccharide  (EXP,ISO)
magnesium atom  (ISO)
magnesium oxide  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (EXP)
methacholine chloride  (ISO)
methidathion  (ISO)
methotrexate  (EXP)
methyl methanesulfonate  (EXP)
methylarsonic acid  (ISO)
methylmercury chloride  (EXP)
methylmercury(1+)  (ISO)
mifepristone  (EXP)
Mitotane  (ISO)
monodansylcadaverine  (ISO)
motexafin gadolinium  (EXP)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-acetyl-L-cysteine  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naloxone  (ISO)
nefazodone  (ISO)
neoechinulin A  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (EXP)
nicotine  (EXP,ISO)
nimesulide  (ISO)
nitrates  (ISO)
Nonidet P-40  (EXP)
notoginsenoside R1  (ISO)
o-anisidine  (EXP)
ochratoxin A  (EXP,ISO)
octreotide  (ISO)
osthole  (EXP)
ozone  (EXP,ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentobarbital  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosphoramide mustard  (ISO)
prochloraz  (ISO)
progesterone  (ISO)
propylparaben  (EXP)
prostaglandin E2  (EXP)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quercitrin  (EXP)
quinidine  (ISO)
resiniferatoxin  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 203580  (ISO)
selenium atom  (EXP)
serpentine asbestos  (ISO)
sesquiterpene  (EXP)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium stibogluconate  (EXP)
Soman  (ISO)
sterigmatocystin  (ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
tolcapone  (ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
trimethyltin  (ISO)
triptonide  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
vorinostat  (EXP)
WR-1065  (ISO)
zerumbone  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP,ISO)
zinc molecular entity  (EXP)
zinc protoporphyrin  (EXP)
zinc(0)  (EXP,ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve development  (IEA,ISS)
apoptotic process  (IEA)
cell surface receptor signaling pathway  (IEA,ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to mechanical stimulus  (IEP)
cytokine-mediated signaling pathway  (IEA,ISO,ISS)
defense response  (IEA,ISO)
defense response to bacterium  (IEA,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (TAS)
inflammatory response  (IBA,IEA,ISO,ISS)
intrinsic apoptotic signaling pathway in response to DNA damage  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cardiac muscle hypertrophy  (IEA)
negative regulation of extracellular matrix constituent secretion  (IEA,ISS)
negative regulation of gene expression  (ISO)
negative regulation of inflammatory response  (IMP)
negative regulation of interleukin-6 production  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of apoptotic process involved in morphogenesis  (IEA,ISS)
positive regulation of gene expression  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IEP)
positive regulation of inflammatory response  (IEA,ISO,ISS)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,IMP,ISO,ISS)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IMP)
prostaglandin metabolic process  (IEA)
protein localization to plasma membrane  (IMP)
pulmonary valve development  (IEA,ISS)
regulation of apoptotic process  (ISO)
regulation of establishment of endothelial barrier  (IMP)
regulation of tumor necrosis factor-mediated signaling pathway  (IEA,ISO)
response to alkaloid  (ISO)
response to amino acid  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to wounding  (ISO)
signal transduction  (IEA)
transcription by RNA polymerase II  (IEA,ISO)
tumor necrosis factor-mediated signaling pathway  (IEA,IMP,ISO,TAS)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
AA amyloidosis  (IAGP)
Abdominal pain  (IAGP)
Abnormal myocardium morphology  (IAGP)
Abnormal sacroiliac joint morphology  (IAGP)
Arthralgia  (IAGP)
Arthritis  (IAGP)
Autosomal dominant inheritance  (IAGP)
Behavioral abnormality  (IAGP)
Bone pain  (IAGP)
Bruising susceptibility  (IAGP)
Cellulitis  (IAGP)
Cervical lymphadenopathy  (IAGP)
Chest pain  (IAGP)
Chondrocalcinosis  (IAGP)
Chronic constipation  (IAGP)
Chronic diarrhea  (IAGP)
Conjunctival hyperemia  (IAGP)
Conjunctivitis  (IAGP)
Constipation  (IAGP)
Cranial nerve paralysis  (IAGP)
Diarrhea  (IAGP)
Elevated circulating C-reactive protein concentration  (IAGP)
Elevated erythrocyte sedimentation rate  (IAGP)
Erysipelas  (IAGP)
Erythema  (IAGP)
Fasciitis  (IAGP)
Febrile seizure (within the age range of 3 months to 6 years)  (IAGP)
Gastrointestinal hemorrhage  (IAGP)
Headache  (IAGP)
Hepatic amyloidosis  (IAGP)
Hepatomegaly  (IAGP)
Hepatosplenomegaly  (IAGP)
Hypermelanotic macule  (IAGP)
Intestinal obstruction  (IAGP)
Joint swelling  (IAGP)
Knee joint hypermobility  (IAGP)
Leukocytosis  (IAGP)
Lymphadenopathy  (IAGP)
Maculopapular exanthema  (IAGP)
Migraine  (IAGP)
Muscle stiffness  (IAGP)
Myalgia  (IAGP)
Myositis  (IAGP)
Oligoarthritis  (IAGP)
Orchitis  (IAGP)
Paresthesia  (IAGP)
Pericarditis  (IAGP)
Periorbital edema  (IAGP)
Peritonitis  (IAGP)
Pleuritis  (IAGP)
Polyarticular arthritis  (IAGP)
Recurrent fever  (IAGP)
Recurrent pharyngitis  (IAGP)
Skin rash  (IAGP)
Splenomegaly  (IAGP)
Uveitis  (IAGP)
Vasculitis  (IAGP)
Vertigo  (IAGP)
Vomiting  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus. Aderka D, etal., Arthritis Rheum. 1993 Aug;36(8):1111-20.
2. Increased serum levels of soluble receptors for tumor necrosis factor in cancer patients. Aderka D, etal., Cancer Res. 1991 Oct 15;51(20):5602-7.
3. Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush. Agudo M, etal., Mol Vis. 2008 Jun 3;14:1050-63.
4. A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis. Arntz OJ, etal., Arthritis Res Ther. 2010;12(2):R61. doi: 10.1186/ar2974. Epub 2010 Apr 6.
5. Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis. Aten J, etal., J Am Soc Nephrol. 2000 Aug;11(8):1426-38.
6. Enhancement of the survival of engrafted mesenchymal stem cells in the ischemic heart by TNFR gene transfection. Bao C, etal., Biochem Cell Biol. 2010 Aug;88(4):629-34.
7. Moxibustion inhibits apoptosis and tumor necrosis factor-alpha/tumor necrosis factor receptor 1 in the colonic epithelium of Crohn's disease model rats. Bao CH, etal., Dig Dis Sci. 2012 Sep;57(9):2286-95. doi: 10.1007/s10620-012-2161-0. Epub 2012 Apr 25.
8. TNFR2 interposes the proliferative and NF-kappaB-mediated inflammatory response by podocytes to TNF-alpha. Bruggeman LA, etal., Lab Invest. 2011 Mar;91(3):413-25. doi: 10.1038/labinvest.2010.199. Epub 2011 Jan 10.
9. Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Calfee CS, etal., Crit Care Med. 2011 Jan 28.
10. Expression of tumour necrosis factor receptors by bronchoalveolar cells in hypersensitivity pneumonitis. Chen B, etal., Eur Respir J. 2005 Jun;25(6):1039-43.
11. The effect of intra-articular injection of different concentrations of ozone on the level of TNF-alpha, TNF-R1, and TNF-R2 in rats with rheumatoid arthritis. Chen H, etal., Rheumatol Int. 2013 May;33(5):1223-7. doi: 10.1007/s00296-012-2529-7. Epub 2012 Oct 2.
12. Tumor Necrosis Factor-Alpha Antagonist Reduces Apoptosis of Neurons and Oligodendroglia in Rat Spinal Cord Injury. Chen KB, etal., Spine (Phila Pa 1976). 2011 Jan 8.
13. TNF-alpha enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury. Chen X, etal., Exp Neurol. 2011 Feb;227(2):279-86. Epub 2010 Dec 9.
14. Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients. Cheng X, etal., J Alzheimers Dis. 2010;19(2):621-30. doi: 10.3233/JAD-2010-1253.
15. TNF-alpha is a key regulator of MUC1, an anti-inflammatory molecule, during airway Pseudomonas aeruginosa infection. Choi S, etal., Am J Respir Cell Mol Biol. 2011 Feb;44(2):255-60. Epub 2010 May 6.
16. Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. Constantin CE, etal., J Neurosci. 2008 May 7;28(19):5072-81.
17. Tumor necrosis factor receptor 1 expression is upregulated in dendritic cells in patients with chronic HCV who respond to therapy. Cubillas R, etal., Hepat Res Treat. 2010;2010:429243. doi: 10.1155/2010/429243. Epub 2010 Aug 3.
18. Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease. Culpan D, etal., Exp Gerontol. 2007 Jun;42(6):538-44. doi: 10.1016/j.exger.2006.12.001. Epub 2007 Jan 30.
19. Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. Cunningham PN, etal., J Immunol. 2002 Jun 1;168(11):5817-23.
20. The presence of TNF-alpha and TNFR1 in aseptic root resorption. A preliminary study. Curl L and Sampson W, Aust Orthod J. 2011 Nov;27(2):102-9.
21. Exercise preconditioning reduces brain damage and inhibits TNF-alpha receptor expression after hypoxia/reoxygenation: an in vivo and in vitro study. Ding YH, etal., Curr Neurovasc Res. 2006 Nov;3(4):263-71.
22. Circulating levels of TNF-alpha and its soluble receptors in the plasma of patients with epithelial ovarian cancer. Dobrzycka B, etal., Eur Cytokine Netw. 2009 Sep;20(3):131-4.
23. A novel missense mutation (C30S) in the gene encoding tumor necrosis factor receptor 1 linked to autosomal-dominant recurrent fever with localized myositis in a French family. Dode C, etal., Arthritis Rheum. 2000 Jul;43(7):1535-42.
24. Sources of alveolar soluble TNF receptors during acute lung injury of different etiologies. Dorr AD, etal., J Appl Physiol. 2011 Apr 21.
25. Cytokine inhibitors: soluble tumor necrosis factor receptor 1 and interleukin-1 receptor antagonist in Behcet's disease. Duzgun N, etal., Rheumatol Int. 2005 Jan;25(1):1-5. Epub 2003 Nov 5.
26. Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study. Eagan TM, etal., Eur Respir J. 2010 Mar;35(3):540-8. Epub 2009 Jul 30.
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PMID:19948975   PMID:20045350   PMID:20062090   PMID:20066156   PMID:20074459   PMID:20074469   PMID:20080539   PMID:20098615   PMID:20100586   PMID:20103630   PMID:20237496   PMID:20331378  
PMID:20333651   PMID:20371430   PMID:20400394   PMID:20421368   PMID:20430450   PMID:20430728   PMID:20446090   PMID:20448643   PMID:20452482   PMID:20453000   PMID:20457915   PMID:20458742  
PMID:20483718   PMID:20497634   PMID:20503287   PMID:20506103   PMID:20511226   PMID:20516030   PMID:20532935   PMID:20564232   PMID:20566746   PMID:20568250   PMID:20602615   PMID:20628086  
PMID:20635912   PMID:20654748   PMID:20673868   PMID:20695192   PMID:20811626   PMID:20825417   PMID:20930310   PMID:20955203   PMID:20980627   PMID:21029567   PMID:21037509   PMID:21048031  
PMID:21068102   PMID:21113135   PMID:21113948   PMID:21124859   PMID:21132303   PMID:21153350   PMID:21153367   PMID:21153368   PMID:21225694   PMID:21256825   PMID:21284530   PMID:21288590  
PMID:21315128   PMID:21316985   PMID:21321109   PMID:21331078   PMID:21350240   PMID:21385537   PMID:21393509   PMID:21399635   PMID:21410936   PMID:21418516   PMID:21420073   PMID:21523796  
PMID:21552549   PMID:21555518   PMID:21565411   PMID:21567205   PMID:21602493   PMID:21724995   PMID:21737329   PMID:21789618   PMID:21813053   PMID:21819445   PMID:21833088   PMID:21850048  
PMID:21873635   PMID:21880774   PMID:21920667   PMID:21930713   PMID:21976655   PMID:21988832   PMID:22028622   PMID:22036455   PMID:22059991   PMID:22099304   PMID:22115362   PMID:22179575  
PMID:22209080   PMID:22215119   PMID:22228740   PMID:22235167   PMID:22272576   PMID:22281876   PMID:22288185   PMID:22297296   PMID:22311714   PMID:22343913   PMID:22396498   PMID:22535754  
PMID:22547679   PMID:22568977   PMID:22609894   PMID:22617158   PMID:22675546   PMID:22733818   PMID:22749881   PMID:22817896   PMID:22848449   PMID:22860894   PMID:22945416   PMID:22994200  
PMID:23019260   PMID:23032187   PMID:23081800   PMID:23086255   PMID:23117241   PMID:23160117   PMID:23182003   PMID:23205868   PMID:23207486   PMID:23269568   PMID:23316846   PMID:23321203  
PMID:23322460   PMID:23322903   PMID:23360651   PMID:23382219   PMID:23405158   PMID:23429285   PMID:23461592   PMID:23490134   PMID:23493346   PMID:23494522   PMID:23505244   PMID:23526964  
PMID:23532748   PMID:23619127   PMID:23620528   PMID:23624563   PMID:23648065   PMID:23745996   PMID:23746843   PMID:23894535   PMID:23908318   PMID:23955153   PMID:23965844   PMID:23975421  
PMID:24024893   PMID:24070898   PMID:24098568   PMID:24130170   PMID:24130709   PMID:24130718   PMID:24165468   PMID:24174586   PMID:24301904   PMID:24361886   PMID:24386183   PMID:24393624  
PMID:24440909   PMID:24497084   PMID:24511129   PMID:24557113   PMID:24576746   PMID:24578190   PMID:24587316   PMID:24623026   PMID:24658140   PMID:24668260   PMID:24681099   PMID:24708999  
PMID:24726327   PMID:24735611   PMID:24736233   PMID:24746195   PMID:24748490   PMID:24758719   PMID:24782596   PMID:24783218   PMID:24803721   PMID:24805855   PMID:24836286   PMID:24844917  
PMID:24851923   PMID:24896334   PMID:24896343   PMID:24965843   PMID:24966471   PMID:24980434   PMID:25008247   PMID:25010932   PMID:25034210   PMID:25039986   PMID:25098821   PMID:25229256  
PMID:25230327   PMID:25241761   PMID:25255422   PMID:25263964   PMID:25271196   PMID:25275127   PMID:25288570   PMID:25292131   PMID:25318944   PMID:25351965   PMID:25388546   PMID:25402006  
PMID:25416967   PMID:25443631   PMID:25461388   PMID:25466434   PMID:25531320   PMID:25681446   PMID:25684197   PMID:25735143   PMID:25744939   PMID:25749018   PMID:25770168   PMID:25783484  
PMID:25816133   PMID:25817730   PMID:25828588   PMID:25840914   PMID:25860248   PMID:25888769   PMID:25889297   PMID:25909160   PMID:25911380   PMID:26055088   PMID:26083468   PMID:26122654  
PMID:26177311   PMID:26178412   PMID:26183779   PMID:26186194   PMID:26202849   PMID:26208457   PMID:26212014   PMID:26224639   PMID:26270730   PMID:26289850   PMID:26439863   PMID:26475675  
PMID:26496610   PMID:26499922   PMID:26574625   PMID:26598380   PMID:26616867   PMID:26670046   PMID:26755728   PMID:26777482   PMID:26802121   PMID:26813918   PMID:26845019   PMID:26854079  
PMID:26888535   PMID:26928194   PMID:26963895   PMID:26964514   PMID:26993379   PMID:27003829   PMID:27040725   PMID:27062399   PMID:27068267   PMID:27175635   PMID:27211553   PMID:27288458  
PMID:27307491   PMID:27321185   PMID:27323176   PMID:27332769   PMID:27362805   PMID:27475257   PMID:27528091   PMID:27544753   PMID:27545878   PMID:27552911   PMID:27560715   PMID:27591049  
PMID:27684048   PMID:27791020   PMID:27793577   PMID:27834853   PMID:27990755   PMID:28096440   PMID:28115640   PMID:28116820   PMID:28126963   PMID:28134085   PMID:28150360   PMID:28159803  
PMID:28199753   PMID:28205554   PMID:28222663   PMID:28238825   PMID:28256549   PMID:28363009   PMID:28367848   PMID:28384542   PMID:28388439   PMID:28389814   PMID:28401452   PMID:28427379  
PMID:28478120   PMID:28489742   PMID:28494239   PMID:28503569   PMID:28514442   PMID:28601698   PMID:28659487   PMID:28667032   PMID:28688764   PMID:28765050   PMID:28815559   PMID:28817177  
PMID:28830973   PMID:28927886   PMID:29108854   PMID:29117863   PMID:29128118   PMID:29148404   PMID:29212072   PMID:29233887   PMID:29243062   PMID:29317797   PMID:29401539   PMID:29404828  
PMID:29416926   PMID:29431638   PMID:29470995   PMID:29535371   PMID:29547707   PMID:29579081   PMID:29621649   PMID:29625336   PMID:29686027   PMID:29734462   PMID:29740434   PMID:29879997  
PMID:30030263   PMID:30059939   PMID:30075559   PMID:30156861   PMID:30242998   PMID:30287518   PMID:30289218   PMID:30374604   PMID:30414969   PMID:30418111   PMID:30420664   PMID:30504227  
PMID:30561431   PMID:30762338   PMID:30793619   PMID:30989829   PMID:31135083   PMID:31207020   PMID:31363067   PMID:31363069   PMID:31382980   PMID:31406107   PMID:31429073   PMID:31494339  
PMID:31559449   PMID:31586650   PMID:31638426   PMID:31710744   PMID:31871319   PMID:31898971   PMID:31906244   PMID:31928491   PMID:31960514   PMID:32030920   PMID:32083339   PMID:32155316  
PMID:32159413   PMID:32272224   PMID:32281000   PMID:32389622   PMID:32561252   PMID:32563262   PMID:32643269   PMID:32680471   PMID:32690868   PMID:32831641   PMID:32929358   PMID:32968279  
PMID:33029495   PMID:33131906   PMID:33162992   PMID:33242241   PMID:33311474   PMID:33459100   PMID:33469115   PMID:33495441   PMID:33495445   PMID:33603056   PMID:33637726   PMID:33713325  
PMID:33751344   PMID:33815386   PMID:33845483   PMID:33918875   PMID:33949291   PMID:33961781   PMID:34062547   PMID:34305946   PMID:34315543   PMID:34359880   PMID:34363702   PMID:34415356  
PMID:34503962   PMID:34610306   PMID:34614352   PMID:34739338   PMID:34831323   PMID:34839354   PMID:34995801   PMID:35163403   PMID:35170849   PMID:35296554   PMID:35462541   PMID:35681430  
PMID:35726234   PMID:35946512   PMID:36012347   PMID:36012570  


Genomics

Comparative Map Data
TNFRSF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,328,771 - 6,342,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl126,328,757 - 6,342,114 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,437,937 - 6,451,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,308,184 - 6,321,522 (-)NCBINCBI36Build 36hg18NCBI36
Build 34126,308,184 - 6,321,522NCBI
Celera128,054,567 - 8,067,927 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,291,179 - 6,304,533 (-)NCBIHuRef
CHM1_1126,437,153 - 6,450,509 (-)NCBICHM1_1
T2T-CHM13v2.0126,338,163 - 6,351,461 (-)NCBIT2T-CHM13v2.0
Tnfrsf1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,326,686 - 125,339,446 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6125,326,325 - 125,339,447 (+)EnsemblGRCm39 Ensembl
GRCm386125,349,723 - 125,362,483 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,349,362 - 125,362,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,299,741 - 125,312,501 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366125,315,374 - 125,328,104 (+)NCBIMGSCv36mm8
Celera6127,020,792 - 127,033,747 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map659.32NCBI
Tnfrsf1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24158,150,815 - 158,163,592 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4158,150,820 - 158,163,591 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4164,380,489 - 164,393,199 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04160,163,415 - 160,176,125 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04158,802,250 - 158,814,961 (+)NCBIRnor_WKY
Rnor_6.04157,864,905 - 157,877,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,864,969 - 157,877,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,881,368 - 224,894,089 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44162,172,563 - 162,185,252 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14162,417,498 - 162,430,188 (+)NCBI
Celera4146,886,949 - 146,899,646 (+)NCBICelera
RH 3.4 Map41000.9RGD
Cytogenetic Map4q42NCBI
Tnfrsf1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554133,981,400 - 3,996,021 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554133,982,670 - 3,996,320 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,374,256 - 6,387,613 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,374,257 - 6,387,613 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,457,617 - 6,470,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TNFRSF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,641,837 - 38,654,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,638,753 - 38,700,282 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,959,778 - 7,972,628 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,997,951 - 39,010,819 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12738,870,492 - 38,883,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,911,954 - 38,924,837 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,438,485 - 7,451,382 (-)NCBIUU_Cfam_GSD_1.0
Tnfrsf1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,735,979 - 102,753,899 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367091,407,327 - 1,421,448 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl564,319,051 - 64,331,909 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1564,319,349 - 64,331,876 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,780,726 - 66,793,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,364,544 - 6,378,880 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,364,330 - 6,378,902 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,856,767 - 1,871,090 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfrsf1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,111,630 - 3,122,711 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,111,244 - 3,123,041 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D12S356  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p13.2UniSTS
Marshfield Genetic Map1214.23RGD
Marshfield Genetic Map1214.23UniSTS
Genethon Genetic Map1215.5UniSTS
deCODE Assembly Map1215.99UniSTS
Whitehead-YAC Contig Map12 UniSTS
RH75052  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,437,956 - 6,438,204UniSTSGRCh37
Build 36126,308,217 - 6,308,465RGDNCBI36
Celera128,054,600 - 8,054,848RGD
Cytogenetic Map12p13.2UniSTS
HuRef126,291,212 - 6,291,460UniSTS
D12S889  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,448,885 - 6,449,068UniSTSGRCh37
Build 36126,319,146 - 6,319,329RGDNCBI36
Celera128,065,529 - 8,065,712RGD
Cytogenetic Map12p13.2UniSTS
HuRef126,302,141 - 6,302,318UniSTS
GDB:214852  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,439,308 - 6,439,901UniSTSGRCh37
Build 36126,309,569 - 6,310,162RGDNCBI36
Celera128,055,952 - 8,056,545RGD
Cytogenetic Map12p13.2UniSTS
HuRef126,292,564 - 6,293,157UniSTS
GDB:384764  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,443,088 - 6,443,268UniSTSGRCh37
Build 36126,313,349 - 6,313,529RGDNCBI36
Celera128,059,732 - 8,059,912RGD
Cytogenetic Map12p13.2UniSTS
HuRef126,296,344 - 6,296,524UniSTS
STS-M58286  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,438,225 - 6,438,464UniSTSGRCh37
Build 36126,308,486 - 6,308,725RGDNCBI36
Celera128,054,869 - 8,055,108RGD
Cytogenetic Map12p13.2UniSTS
HuRef126,291,481 - 6,291,720UniSTS
GeneMap99-GB4 RH Map1241.1UniSTS
NCBI RH Map1294.1UniSTS
G15949  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,437,963 - 6,438,161UniSTSGRCh37
Build 36126,308,224 - 6,308,422RGDNCBI36
Celera128,054,607 - 8,054,805RGD
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map12p13.2UniSTS
HuRef126,291,219 - 6,291,417UniSTS
WI-18755  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,438,030 - 6,438,167UniSTSGRCh37
Build 36126,308,291 - 6,308,428RGDNCBI36
Celera128,054,674 - 8,054,811RGD
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map12p13.2UniSTS
HuRef126,291,286 - 6,291,423UniSTS
GeneMap99-GB4 RH Map1234.19UniSTS
Whitehead-RH Map1265.7UniSTS
NCBI RH Map1288.6UniSTS
D8S2279  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map17q24.2UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map12q24.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map6p21.1-p12UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map8p23UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map13q14.1-q14.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map17p13.1-p12UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map17p12-p11.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map3q27UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map17q12UniSTS
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Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map7q31.1-q31.2UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map3p26.1-p25.1UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map6q16.3UniSTS
Cytogenetic Map17q24-q25UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic MapXq27.1UniSTS
Cytogenetic Map8q12.3UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map4q35.2UniSTS
Cytogenetic Map3p26.1UniSTS
Cytogenetic Map3p11.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map2q21.2UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map18q12.3UniSTS
Cytogenetic Map18p11.3UniSTS
Cytogenetic Map17q11.1UniSTS
Cytogenetic Map15q25.1UniSTS
Cytogenetic Map13q12.3UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map12q12-q13UniSTS
Cytogenetic Map12q14UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map2q32-q34UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map2p15-p13UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map19q13.33-q13.41UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map6q23-q24UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map13q11-q12UniSTS
Cytogenetic Map6p12.3-p11.2UniSTS
Cytogenetic Map6q16.1-q16.3UniSTS
Cytogenetic Map22q11UniSTS
Cytogenetic Map7q31.2UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map3q25.2UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map3q23-q24UniSTS
Cytogenetic Map3q12UniSTS
Cytogenetic Map7q11.1UniSTS
Cytogenetic Map3q22.3UniSTS
Cytogenetic Map7q21.3UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map22q12-q13UniSTS
Cytogenetic Map4q23UniSTS
Cytogenetic MapXp22.12UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map18q21.3UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map6p23UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map1q24.3UniSTS
Cytogenetic Map9q33.1UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map2p16.2UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map16p12UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map13q22.1UniSTS
Cytogenetic Map2q12.2UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map4q21UniSTS
Cytogenetic Map13q12.2UniSTS
Cytogenetic Map9q31-q33UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map1q23UniSTS
Cytogenetic Map11q12-q13UniSTS
Cytogenetic Map11q13.3UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map11q12.1UniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map8p21UniSTS
Cytogenetic Map19q13.1-q13.2UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map7q36.2UniSTS
Cytogenetic Map4q32.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map9q32-q33.3UniSTS
Cytogenetic Map9q22.1-q22.2UniSTS
Cytogenetic Map3q26.1-q26.2UniSTS
Cytogenetic Map5q31-q34UniSTS
Cytogenetic Map9q33-q34UniSTS
Cytogenetic Map5q11.2-q13.2UniSTS
Cytogenetic Map13q32UniSTS
Cytogenetic Map9q22.32UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map4q28.1UniSTS
Cytogenetic Map5q22UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic MapXq13.3UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map3p26.3UniSTS
Cytogenetic Map2q11.1UniSTS
Cytogenetic Map21q11.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map2q31.1-q31.2UniSTS
Cytogenetic MapXp22.31UniSTS
Cytogenetic MapXp21.3UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map4q28.2UniSTS
Cytogenetic Map3p14.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map20q13.2UniSTS
Cytogenetic Map14q11.2-q12UniSTS
Cytogenetic Map3p24UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map11q24.3UniSTS
Cytogenetic Map11q14.3UniSTS
Cytogenetic Map10q25.2UniSTS
Cytogenetic Map3q25.1UniSTS
Cytogenetic Map8q13UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map3p22.3UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map8q23.3UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic Map11cen-q12UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map12q21UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map7q22-q31UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map20q13.3-qterUniSTS
Cytogenetic Map1p35-p34UniSTS
Cytogenetic Map4p13-p12UniSTS
Cytogenetic Map10q21-q22UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map7p13-p11.1UniSTS
Cytogenetic Map9q31-q34UniSTS
Cytogenetic Map7q21.1-q22UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic MapXp22.13UniSTS
Cytogenetic Map13q12.12UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1pUniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map2qUniSTS
Cytogenetic Map5q13.1UniSTS
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map2p22UniSTS
Cytogenetic Map5q14.3UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map5q23.2UniSTS
Cytogenetic Map2p24.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map9p21.1UniSTS
Cytogenetic Map9q34.2-q34.3UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5208
Count of miRNA genes:1177
Interacting mature miRNAs:1475
Transcripts:ENST00000162749, ENST00000366159, ENST00000437813, ENST00000440083, ENST00000534885, ENST00000535038, ENST00000535958, ENST00000536194, ENST00000536717, ENST00000537842, ENST00000538363, ENST00000539372, ENST00000540022, ENST00000543048, ENST00000543359, ENST00000543995
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1
Medium 2439 2938 1724 623 1756 464 4354 2154 2259 417 1452 1575 174 1 1204 2785 6 2
Low 52 2 1 158 1 3 43 1471 2 4 29 1 3
Below cutoff 1 31 4 3 9

Sequence

Nucleotide Sequences
RefSeq Transcripts