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Gene: ADRA2C (adrenoceptor alpha 2C) Homo sapiens
Symbol: ADRA2C
Name: adrenoceptor alpha 2C
Description: Exhibits several functions, including alpha-2A adrenergic receptor binding activity; alpha2-adrenergic receptor activity; and protein dimerization activity. Involved in several processes, including positive regulation of neuron differentiation; positive regulation of protein phosphorylation; and receptor transactivation. Localizes to cytoplasm and integral component of plasma membrane. Implicated in congestive heart failure.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADRA2L2; ADRA2RL2; ADRARL2; adrenergic receptor, alpha 2c; adrenergic, alpha-2C-, receptor; alpha-2 adrenergic receptor subtype C4; alpha-2C adrenergic receptor; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; alpha-2C-adrenergic receptor; alpha-2CAR; alpha2-AR-C4; ALPHA2CAR
Mus musculus (house mouse) : Adra2c (adrenergic receptor, alpha 2c)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adra2c (adrenoceptor alpha 2C)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2C (adrenoceptor alpha 2C)
Canis lupus familiaris (dog) : ADRA2C (adrenoceptor alpha 2C)
Sus scrofa (pig) : ADRA2C (adrenoceptor alpha 2C)
Chlorocebus sabaeus (African green monkey) : ADRA2C (adrenoceptor alpha 2C)
Heterocephalus glaber (naked mole-rat) : Adra2c (adrenoceptor alpha 2C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl43,766,348 - 3,768,526 (+)EnsemblGRCh38hg38GRCh38
GRCh3843,766,385 - 3,768,526 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3743,768,296 - 3,770,253 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,738,094 - 3,740,051 (+)NCBINCBI36hg18NCBI36
Build 3443,804,398 - 3,807,217NCBI
Celera43,671,112 - 3,673,097 (+)NCBI
Cytogenetic Map4p16.3NCBI
HuRef43,705,412 - 3,707,390 (+)NCBIHuRef
CHM1_143,766,238 - 3,768,183 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADRA2C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737142
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.