Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DIO1 (iodothyronine deiodinase 1) Homo sapiens
Analyze
Symbol: DIO1
Name: iodothyronine deiodinase 1
Description: Predicted to have thyroxine 5'-deiodinase activity. Predicted to be involved in thyroid hormone metabolic process. Predicted to localize to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5DI; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; DIOI; iodothyronine deiodinase type 1; MGC130050; MGC130051; thyroxine 5'-deiodinase; thyroxine deiodinase type I (selenoprotein); TXDI1; type 1 DI; type I iodothyronine deiodinase; type-I 5'-deiodinase; type-I 5'deiodinase
Orthologs:
Mus musculus (house mouse) : Dio1 (deiodinase, iodothyronine, type I)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dio1 (iodothyronine deiodinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dio1 (iodothyronine deiodinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DIO1 (iodothyronine deiodinase 1)
Canis lupus familiaris (dog) : DIO1 (iodothyronine deiodinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dio1 (iodothyronine deiodinase 1)
Sus scrofa (pig) : DIO1 (iodothyronine deiodinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38153,894,187 - 53,911,086 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37154,359,860 - 54,376,763 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36154,132,449 - 54,149,347 (+)NCBINCBI36hg18NCBI36
Build 34154,071,881 - 54,088,779NCBI
Celera152,647,532 - 52,664,449 (+)NCBI
Cytogenetic Map1p32.3NCBI
HuRef152,475,576 - 52,492,483 (+)NCBIHuRef
CHM1_1154,476,232 - 54,493,132 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DIO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735269
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.