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Gene: FTL (ferritin light chain) Homo sapiens
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Symbol: FTL
Name: ferritin light chain
RGD ID: 1346340
Description: Exhibits identical protein binding activity and iron ion binding activity. Predicted to be involved in intracellular sequestering of iron ion. Localizes to autolysosome and intracellular ferritin complex. Implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Biomarker of COVID-19.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ferritin L subunit; ferritin L-chain; ferritin light polypeptide-like 3; ferritin, light polypeptide; LFTD; MGC71996; NBIA3; neurodegeneration with brain iron accumulation 3
Orthologs:
Mus musculus (house mouse) : Ftl1 (ferritin light polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ftl1 (ferritin light chain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ftl (ferritin light chain)
Pan paniscus (bonobo/pygmy chimpanzee) : FTL (ferritin light chain)
Canis lupus familiaris (dog) : FTL (ferritin light chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ftl (ferritin light chain)
Sus scrofa (pig) : FTL (ferritin light chain)
Chlorocebus sabaeus (African green monkey) : FTL (ferritin light chain)
Heterocephalus glaber (naked mole-rat) : Ftl (ferritin light chain)
more info ...
Related Pseudogenes: AC106028.1   FTLP1   FTLP10   FTLP11   FTLP12   FTLP13   FTLP14   FTLP15   FTLP16   FTLP17   FTLP18   FTLP19   FTLP2   FTLP3   FTLP4   FTLP5   FTLP6   FTLP7   FTLP8   FTLP9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1948,965,309 - 48,966,879 (+)EnsemblGRCh38hg38GRCh38
GRCh381948,963,941 - 48,966,879 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,467,659 - 49,470,136 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,160,378 - 54,161,948 (+)NCBINCBI36hg18NCBI36
Build 341954,160,377 - 54,161,947NCBI
Celera1946,335,916 - 46,337,486 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1945,845,481 - 45,847,051 (+)NCBIHuRef
CHM1_11949,470,772 - 49,472,342 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

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RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
 
More on FTL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346340
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.