Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NF2 (neurofibromin 2) Homo sapiens
Symbol: NF2
Name: neurofibromin 2
Description: Predicted to have actin binding activity. Involved in several processes, including Schwann cell proliferation; positive regulation of stress fiber assembly; and regulation of signal transduction. Localizes to several cellular components, including the early endosome; nucleolus; and perinuclear region of cytoplasm. Implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Biomarker of acoustic neuroma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACN; BANF; merlin; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin-2; SCH; schwannomerlin; schwannomin
Mus musculus (house mouse) : Nf2 (neurofibromin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nf2 (neurofibromin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nf2 (neurofibromin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NF2 (neurofibromin 2)
Canis lupus familiaris (dog) : NF2 (neurofibromin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nf2 (neurofibromin 2)
Sus scrofa (pig) : NF2 (neurofibromin 2)
Chlorocebus sabaeus (green monkey) : NF2 (neurofibromin 2)
Heterocephalus glaber (naked mole-rat) : Nf2 (neurofibromin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2229,603,556 - 29,698,598 (+)Ensembl
GRCh382229,603,556 - 29,698,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372229,999,545 - 30,094,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,329,565 - 28,424,587 (+)NCBINCBI36hg18NCBI36
Build 342228,324,118 - 28,419,137NCBI
Celera2213,799,281 - 13,894,313 (+)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2212,962,966 - 13,057,866 (+)NCBIHuRef
CHM1_12229,958,840 - 30,053,867 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants