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Gene: OSBP2 (oxysterol binding protein 2) Homo sapiens
Symbol: OSBP2
Name: oxysterol binding protein 2
Description: Exhibits cholesterol binding activity. Predicted to be involved in spermatid development and sterol transport. Predicted to localize to cytosol; perinuclear endoplasmic reticulum; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HLM; ORP-4; ORP4; OSBP-related protein 4; OSBPL1; OSBPL4; oxysterol binding protein-like 1; oxysterol binding protein-related protein 4; oxysterol-binding protein 2; oxysterol-binding protein-related protein 4
Mus musculus (house mouse) : Osbp2 (oxysterol binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Osbp2 (oxysterol binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Osbp2 (oxysterol binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : OSBP2 (oxysterol binding protein 2)
Canis lupus familiaris (dog) : OSBP2 (oxysterol binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Osbp2 (oxysterol binding protein 2)
Sus scrofa (pig) : OSBP2 (oxysterol binding protein 2)
Chlorocebus sabaeus (African green monkey) : OSBP2 (oxysterol binding protein 2)
Heterocephalus glaber (naked mole-rat) : Osbp2 (oxysterol binding protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2230,693,782 - 30,907,824 (+)EnsemblGRCh38hg38GRCh38
GRCh382230,693,782 - 30,907,824 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,089,769 - 31,303,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,420,793 - 29,633,811 (+)NCBINCBI36hg18NCBI36
Build 342229,415,418 - 29,628,361NCBI
Celera2214,890,919 - 15,103,949 (+)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2214,053,259 - 14,266,343 (+)NCBIHuRef
CHM1_12231,049,493 - 31,263,683 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on OSBP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321446
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.