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Gene: TPM2 (tropomyosin 2) Homo sapiens
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Symbol: TPM2
Name: tropomyosin 2
Description: Exhibits actin binding activity. Involved in regulation of ATPase activity. Predicted to localize to the actin filament. Implicated in distal arthrogryposis and nemaline myopathy 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AMCD1; beta-tropomyosin; DA1; DA2B; DA2B4; epididymis secretory protein Li 273; HEL-S-273; NEM4; nemaline myopathy type 4; TMSB; tropomyosin 2 (beta); tropomyosin beta chain; tropomyosin-2
Orthologs:
Mus musculus (house mouse) : Tpm2 (tropomyosin 2, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tpm2 (tropomyosin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpm2 (tropomyosin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TPM2 (tropomyosin 2)
Canis lupus familiaris (dog) : TPM2 (tropomyosin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpm2 (tropomyosin 2)
Sus scrofa (pig) : TPM2 (tropomyosin 2)
more info ...
Related Pseudogenes: TPM4P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,681,993 - 35,690,056 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,681,990 - 35,690,583 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,671,990 - 35,680,053 (-)NCBINCBI36hg18NCBI36
Celera935,615,536 - 35,623,601 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,637,598 - 35,645,663 (-)NCBIHuRef
CHM1_1935,681,818 - 35,689,882 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TPM2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605428
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.