Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MAPT (microtubule associated protein tau) Homo sapiens
Analyze
Symbol: MAPT
Name: microtubule associated protein tau
Description: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPTL; MGC138549; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; MTBT1; MTBT2; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; PPND; PPP1R103; TAU
Orthologs:
Mus musculus (house mouse) : Mapt (microtubule-associated protein tau)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapt (microtubule-associated protein tau)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapt (microtubule associated protein tau)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPT (microtubule associated protein tau)
Canis lupus familiaris (dog) : MAPT (microtubule associated protein tau)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapt (microtubule associated protein tau)
Sus scrofa (pig) : MAPT (microtubule associated protein tau)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: Strains:   SHR-Tg(Thy1-MAPT)318   SHR-Tg(Thy1-MAPT)72  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381745,894,382 - 46,028,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371743,971,702 - 44,105,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361741,327,624 - 41,461,547 (+)NCBINCBI36hg18NCBI36
Build 341741,327,623 - 41,458,611NCBI
Celera1740,619,037 - 40,753,014 (+)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1739,635,406 - 39,768,427 (+)NCBIHuRef
CHM1_11744,218,591 - 44,352,524 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences