MAPT Human (R)-lipoic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in increased phosphorylation of MAPT protein] CTD PMID:34133789 MAPT Human (S)-colchicine decreases expression EXP 6480464 Colchicine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human (Z)-ligustilide decreases phosphorylation ISO Mapt (Mus musculus) 6480464 ligustilide results in decreased phosphorylation of MAPT protein CTD PMID:23973442 MAPT Human 1,2-dimethylhydrazine increases expression ISO Mapt (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of MAPT mRNA CTD PMID:22206623 MAPT Human 1,4-benzoquinone multiple interactions EXP 6480464 quinone promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:16180106 MAPT Human 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea multiple interactions EXP 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1 and 3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:21715663 MAPT Human 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression ISO Mapt (Rattus norvegicus) 6480464 chlorcyclizine results in increased expression of MAPT mRNA CTD PMID:21058326 MAPT Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Mapt (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:15329391 MAPT Human 17alpha-ethynylestradiol affects expression ISO Mapt (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of MAPT mRNA CTD PMID:17555576 MAPT Human 17alpha-ethynylestradiol multiple interactions ISO Mapt (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAPT mRNA CTD PMID:17942748 MAPT Human 17alpha-ethynylestradiol increases expression ISO Mapt (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of MAPT mRNA CTD PMID:17942748 MAPT Human 17beta-estradiol multiple interactions EXP 6480464 Tamoxifen inhibits the reaction [Estradiol results in increased expression of MAPT protein] CTD PMID:20579400 MAPT Human 17beta-estradiol multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein] more ... CTD PMID:31715309 and PMID:32738378 MAPT Human 17beta-estradiol increases phosphorylation EXP 6480464 Estradiol results in increased phosphorylation of MAPT protein CTD PMID:27026707 MAPT Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of MAPT mRNA and Estradiol results in increased expression of MAPT protein CTD PMID:20579400 and PMID:31614463 MAPT Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Mapt (Mus musculus) 6480464 [Tetrachlorodibenzodioxin affects the methylation of MAPT intron] which results in decreased expression of MAPT mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MAPT mRNA CTD PMID:17942748 and PMID:33017471 MAPT Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Mapt (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAPT mRNA CTD PMID:32109520 and PMID:33387578 MAPT Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of MAPT mRNA CTD PMID:20106945 and PMID:26238291 MAPT Human 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Mapt (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPT protein CTD PMID:18996433 MAPT Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Mapt (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of MAPT mRNA CTD PMID:16922920 and PMID:17942748 MAPT Human 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Mapt (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 MAPT Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO Mapt (Mus musculus) 6480464 2 more ... CTD PMID:18550172 MAPT Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO Mapt (Mus musculus) 6480464 2 more ... CTD PMID:18550172 MAPT Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO Mapt (Rattus norvegicus) 6480464 2 more ... CTD PMID:19954255 MAPT Human 2,5-hexanedione decreases expression ISO Mapt (Rattus norvegicus) 6480464 2 and 5-hexanedione results in decreased expression of MAPT protein modified form CTD PMID:20554699 MAPT Human 2-hydroxypropanoic acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Lactic Acid CTD PMID:39172838 MAPT Human 2-hydroxypropanoic acid multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Lactic Acid and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Lactic Acid] CTD PMID:39172838 MAPT Human 2-hydroxypropanoic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Lactic Acid] CTD PMID:39172838 MAPT Human 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:24395787 MAPT Human 2-methylcholine affects expression EXP 6480464 beta-methylcholine affects the expression of MAPT mRNA CTD PMID:21179406 MAPT Human 3,3',5-triiodo-L-thyronine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Triiodothyronine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of and results in increased phosphorylation of MAPT protein] CTD PMID:36868496 MAPT Human 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO Mapt (Mus musculus) 6480464 3 more ... CTD PMID:10051481 MAPT Human 3-chloropropane-1,2-diol increases expression ISO Mapt (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of MAPT mRNA and alpha-Chlorohydrin results in increased expression of MAPT protein CTD PMID:28522335 and PMID:34915118 MAPT Human 3-nitropropanoic acid affects localization ISO Mapt (Rattus norvegicus) 6480464 3-nitropropionic acid affects the localization of MAPT protein CTD PMID:17634376 MAPT Human 3-phosphoglyceric acid multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate] CTD PMID:39172838 MAPT Human 3alpha-hydroxy-5beta-pregnan-20-one increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Pregnanolone results in increased phosphorylation of MAPT protein CTD PMID:17443805 MAPT Human 3alpha-hydroxy-5beta-pregnan-20-one decreases expression ISO Mapt (Rattus norvegicus) 6480464 Pregnanolone results in decreased expression of MAPT protein CTD PMID:17443805 MAPT Human 4-hydroxyphenyl retinamide increases expression ISO Mapt (Mus musculus) 6480464 Fenretinide results in increased expression of MAPT mRNA CTD PMID:28973697 MAPT Human 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of MAPT mRNA CTD PMID:16570282 MAPT Human 5-azacytidine decreases expression EXP 6480464 Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human 5-fluorouracil multiple interactions EXP 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 MAPT Human 5-methoxypsoralen multiple interactions ISO Mapt (Mus musculus) 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] CTD PMID:34428446 MAPT Human 5alpha-pregnane-3,20-dione decreases expression ISO Mapt (Rattus norvegicus) 6480464 5-alpha-Dihydroprogesterone results in decreased expression of MAPT protein CTD PMID:17443805 MAPT Human 5alpha-pregnane-3,20-dione increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 5-alpha-Dihydroprogesterone results in increased phosphorylation of MAPT protein CTD PMID:17443805 MAPT Human 6-propyl-2-thiouracil decreases expression ISO Mapt (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of MAPT mRNA CTD PMID:30047161 MAPT Human 7H-xanthine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Xanthine CTD PMID:39172838 MAPT Human 7H-xanthine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Xanthine] CTD PMID:39172838 MAPT Human 8-azaguanine decreases expression EXP 6480464 Azaguanine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human 8-Br-cAMP decreases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of MAPT mRNA CTD PMID:22079614 MAPT Human 9H-xanthine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Xanthine CTD PMID:39172838 MAPT Human 9H-xanthine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Xanthine] CTD PMID:39172838 MAPT Human acetamide increases expression ISO Mapt (Rattus norvegicus) 6480464 acetamide results in increased expression of MAPT mRNA CTD PMID:31881176 MAPT Human acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of MAPT protein CTD PMID:12605413 MAPT Human acrolein increases phosphorylation ISO Mapt (Mus musculus) 6480464 Acrolein results in increased phosphorylation of MAPT protein CTD PMID:12605413 MAPT Human acrolein multiple interactions ISO Mapt (Mus musculus) 6480464 Acrolein promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 MAPT Human acrolein multiple interactions EXP 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] and SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 MAPT Human acrylamide decreases expression ISO Mapt (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of MAPT mRNA CTD PMID:28959563 MAPT Human acrylamide increases phosphorylation EXP 6480464 Acrylamide results in increased phosphorylation of MAPT protein CTD PMID:32763439 MAPT Human acrylamide increases expression ISO Mapt (Rattus norvegicus) 6480464 Acrylamide results in increased expression of MAPT protein CTD PMID:30096436 MAPT Human acrylamide multiple interactions ISO Mapt (Rattus norvegicus) 6480464 calpeptin inhibits the reaction [Acrylamide results in increased expression of MAPT protein] CTD PMID:30096436 MAPT Human acrylamide decreases expression ISO Mapt (Mus musculus) 6480464 Acrylamide results in decreased expression of MAPT mRNA CTD PMID:29261810 MAPT Human acrylamide increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Acrylamide results in increased phosphorylation of MAPT protein CTD PMID:33421551 MAPT Human ADP multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Adenosine Diphosphate] CTD PMID:39172838 MAPT Human ADP increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Adenosine Diphosphate CTD PMID:39172838 MAPT Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of MAPT protein CTD PMID:20106945 MAPT Human aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of MAPT intron CTD PMID:30157460 MAPT Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of MAPT mRNA CTD PMID:21641981 and PMID:22100608 MAPT Human Aflatoxin B2 alpha decreases methylation EXP 6480464 aflatoxin B2 results in decreased methylation of MAPT intron CTD PMID:30157460 MAPT Human agmatine multiple interactions ISO Mapt (Mus musculus) 6480464 Agmatine inhibits the reaction [APP protein results in increased expression of MAPT protein] CTD PMID:32522471 MAPT Human albendazole decreases expression EXP 6480464 Albendazole results in decreased expression of MAPT mRNA and Albendazole results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human aldehydo-D-glucose increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Glucose CTD PMID:39172838 MAPT Human aldehydo-D-glucose multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human aldehydo-D-glucose multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human alexidine decreases expression EXP 6480464 alexidine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human all-trans-retinoic acid affects response to substance EXP 6480464 MAPT protein affects the susceptibility to Tretinoin CTD PMID:16417947 MAPT Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of MAPT mRNA CTD PMID:33167477 MAPT Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of MAPT mRNA more ... CTD PMID:23903816 more ... MAPT Human all-trans-retinoic acid increases expression ISO Mapt (Rattus norvegicus) 6480464 Tretinoin results in increased expression of MAPT protein CTD PMID:17130476 MAPT Human all-trans-retinoic acid multiple interactions EXP 6480464 [BDNF protein co-treated with Tretinoin co-treated with Aluminum Hydroxide] results in increased expression of MAPT protein more ... CTD PMID:16417947 more ... MAPT Human all-trans-retinoic acid multiple interactions ISO Mapt (Mus musculus) 6480464 MAPT protein promotes the reaction [Tretinoin results in increased activity of CASP3 protein] CTD PMID:16417947 MAPT Human alpha-D-galactose multiple interactions ISO Mapt (Mus musculus) 6480464 gentiopicroside analog inhibits the reaction [Galactose results in increased expression of MAPT protein] CTD PMID:36878094 MAPT Human alpha-D-galactose increases expression ISO Mapt (Mus musculus) 6480464 Galactose results in increased expression of MAPT protein CTD PMID:36878094 MAPT Human aluminium atom multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA and Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 MAPT Human aluminium atom increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Aluminum results in increased phosphorylation of MAPT protein CTD PMID:17662457 MAPT Human aluminium hydroxide increases expression EXP 6480464 Aluminum Hydroxide results in increased expression of MAPT protein CTD PMID:37409350 and PMID:37989595 MAPT Human aluminium hydroxide multiple interactions EXP 6480464 [BDNF protein co-treated with Tretinoin co-treated with Aluminum Hydroxide] results in increased expression of MAPT protein more ... CTD PMID:37409350 and PMID:37989595 MAPT Human aluminium sulfate (anhydrous) increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 aluminum sulfate results in increased phosphorylation of MAPT protein CTD PMID:11388372 MAPT Human aluminium(0) increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Aluminum results in increased phosphorylation of MAPT protein CTD PMID:17662457 MAPT Human aluminium(0) multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA and Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 MAPT Human ammonium chloride affects expression ISO Mapt (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of MAPT mRNA CTD PMID:16483693 MAPT Human ammonium chloride decreases expression ISO Mapt (Rattus norvegicus) 6480464 Ammonium Chloride results in decreased expression of MAPT protein modified form CTD PMID:16483693 MAPT Human antimycin A decreases expression EXP 6480464 Antimycin A results in decreased expression of MAPT mRNA CTD PMID:33512557 MAPT Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of MAPT mRNA CTD PMID:24449571 MAPT Human arachidonic acid increases phosphorylation EXP 6480464 Arachidonic Acid results in increased phosphorylation of MAPT protein CTD PMID:12605413 MAPT Human arachidonic acid multiple interactions EXP 6480464 Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] CTD PMID:12605413 MAPT Human aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of MAPT mRNA CTD PMID:33212167 MAPT Human arsane affects expression EXP 6480464 Arsenic metabolite affects the expression of MAPT mRNA CTD PMID:17553662 MAPT Human arsane multiple interactions ISO Mapt (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 MAPT Human arsane affects methylation EXP 6480464 Arsenic affects the methylation of MAPT gene CTD PMID:25304211 MAPT Human arsenic atom affects expression EXP 6480464 Arsenic metabolite affects the expression of MAPT mRNA CTD PMID:17553662 MAPT Human arsenic atom multiple interactions ISO Mapt (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 MAPT Human arsenic atom affects methylation EXP 6480464 Arsenic affects the methylation of MAPT gene CTD PMID:25304211 MAPT Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPT protein CTD PMID:35467087 MAPT Human ascomycin multiple interactions EXP 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein CTD PMID:7723735 MAPT Human ascomycin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein CTD PMID:7723735 MAPT Human astemizole affects binding EXP 6480464 Astemizole binds to MAPT protein alternative form CTD PMID:20110603 MAPT Human ATP multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [annonacin results in decreased abundance of Adenosine Triphosphate] which affects the localization of MAPT protein CTD PMID:17634376 MAPT Human ATP multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Adenosine Triphosphate] CTD PMID:39172838 MAPT Human ATP decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Adenosine Triphosphate CTD PMID:39172838 MAPT Human benfotiamine decreases phosphorylation EXP 6480464 benphothiamine results in decreased phosphorylation of MAPT protein CTD PMID:29860433 MAPT Human benfotiamine multiple interactions ISO Mapt (Mus musculus) 6480464 [benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein more ... CTD PMID:29860433 MAPT Human benzo[a]pyrene multiple interactions ISO Mapt (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of MAPT mRNA] CTD PMID:22228805 MAPT Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of MAPT 5' UTR CTD PMID:27901495 MAPT Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of MAPT mRNA CTD PMID:21871943 more ... MAPT Human benzo[a]pyrene decreases expression ISO Mapt (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of MAPT mRNA CTD PMID:23735875 MAPT Human benzo[a]pyrene increases expression ISO Mapt (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of MAPT mRNA CTD PMID:22228805 MAPT Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:26238291 MAPT Human berberine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA] CTD PMID:29170048 MAPT Human beta-D-fructofuranose 1,6-bisphosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate] CTD PMID:39172838 MAPT Human beta-D-fructofuranose 1,6-bisphosphate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of fructose-1 more ... CTD PMID:39172838 MAPT Human beta-D-fructofuranose 1,6-bisphosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate CTD PMID:39172838 MAPT Human beta-naphthoflavone multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA CTD PMID:18164116 MAPT Human bis(2-ethylhexyl) phthalate increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPT protein CTD PMID:22610992 MAPT Human bis(2-ethylhexyl) phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human bisphenol A increases expression ISO Mapt (Mus musculus) 6480464 bisphenol A results in increased expression of MAPT protein modified form CTD PMID:32278051 MAPT Human bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of MAPT gene CTD PMID:31601247 MAPT Human bisphenol A decreases expression ISO Mapt (Mus musculus) 6480464 bisphenol A results in decreased expression of MAPT mRNA and bisphenol A results in decreased expression of MAPT protein CTD PMID:32156529 and PMID:32512148 MAPT Human bisphenol A multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of MAPT gene CTD PMID:28505145 MAPT Human bisphenol A increases expression ISO Mapt (Rattus norvegicus) 6480464 bisphenol A results in increased expression of MAPT mRNA and bisphenol A results in increased expression of MAPT protein CTD PMID:30816183 more ... MAPT Human bisphenol A affects expression ISO Mapt (Rattus norvegicus) 6480464 bisphenol A affects the expression of MAPT mRNA CTD PMID:25181051 MAPT Human bisphenol A increases phosphorylation ISO Mapt (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of MAPT protein CTD PMID:26779933 and PMID:26923231 MAPT Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MAPT mRNA CTD PMID:22576693 MAPT Human bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of MAPT gene CTD PMID:22576693 MAPT Human bisphenol F decreases expression ISO Mapt (Mus musculus) 6480464 bisphenol F results in decreased expression of MAPT mRNA CTD PMID:38685157 MAPT Human butanal increases expression EXP 6480464 butyraldehyde results in increased expression of MAPT mRNA CTD PMID:26079696 MAPT Human Butylbenzyl phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human cadmium atom multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of and results in increased phosphorylation of MAPT protein more ... CTD PMID:29170048 more ... MAPT Human cadmium atom multiple interactions ISO Mapt (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MAPT mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MAPT protein CTD PMID:30614199 MAPT Human cadmium dichloride multiple interactions ISO Mapt (Mus musculus) 6480464 [[Cadmium Chloride results in decreased activity of CHRM1 protein] which affects the expression of ACHE mRNA alternative form] which results in increased expression of MAPT protein more ... CTD PMID:26026611 more ... MAPT Human cadmium dichloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of and results in increased phosphorylation of MAPT protein more ... CTD PMID:34558789 and PMID:36868496 MAPT Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of MAPT mRNA CTD PMID:38568856 MAPT Human cadmium dichloride increases expression ISO Mapt (Mus musculus) 6480464 Cadmium Chloride results in increased expression of MAPT protein and Cadmium Chloride results in increased expression of MAPT protein modified form CTD PMID:27377441 MAPT Human caffeine affects phosphorylation EXP 6480464 Caffeine affects the phosphorylation of MAPT protein CTD PMID:35688186 MAPT Human calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of MAPT mRNA CTD PMID:26485663 MAPT Human Calpeptin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 calpeptin inhibits the reaction [Acrylamide results in increased expression of MAPT protein] CTD PMID:30096436 MAPT Human calycosin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 7 more ... CTD PMID:36195188 MAPT Human camptothecin decreases expression EXP 6480464 Camptothecin results in decreased expression of MAPT mRNA and Camptothecin results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human cannabidiol affects methylation ISO Mapt (Rattus norvegicus) 6480464 Cannabidiol affects the methylation of MAPT gene CTD PMID:30521419 MAPT Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of MAPT mRNA CTD PMID:28025562 MAPT Human capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of MAPT mRNA CTD PMID:36044967 MAPT Human carbon nanotube decreases expression ISO Mapt (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 MAPT Human CCCP affects localization ISO Mapt (Rattus norvegicus) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein CTD PMID:17634376 MAPT Human CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to MAPT gene] CTD PMID:28238834 MAPT Human chelidonine decreases expression EXP 6480464 chelidonine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human chlordecone decreases expression ISO Mapt (Mus musculus) 6480464 Chlordecone results in decreased expression of MAPT mRNA CTD PMID:33711761 MAPT Human chloroquine affects expression ISO Mapt (Rattus norvegicus) 6480464 Chloroquine affects the expression of MAPT mRNA and Chloroquine affects the expression of MAPT protein CTD PMID:9690670 MAPT Human chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Sertraline results in decreased expression of and results in decreased cleavage of MAPT protein] CTD PMID:33124469 MAPT Human chloroquine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Chloroquine affects the localization of and affects the degradation of MAPT protein CTD PMID:9690670 MAPT Human chlorpyrifos multiple interactions ISO Mapt (Mus musculus) 6480464 BBC3 gene mutant form inhibits the reaction [Chlorpyrifos results in increased phosphorylation of and results in increased expression of MAPT protein] more ... CTD PMID:29665406 and PMID:34289071 MAPT Human chlorpyrifos increases expression ISO Mapt (Mus musculus) 6480464 Chlorpyrifos results in increased expression of MAPT mRNA CTD PMID:37019170 MAPT Human chlorpyrifos increases phosphorylation ISO Mapt (Mus musculus) 6480464 Chlorpyrifos results in increased phosphorylation of MAPT protein CTD PMID:29665406 MAPT Human cholesterol multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form and Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 MAPT Human chromium atom decreases expression EXP 6480464 Chromium results in decreased expression of MAPT mRNA CTD PMID:31953414 MAPT Human chromium atom multiple interactions EXP 6480464 Chromium results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:31953414 MAPT Human ciclopirox decreases expression EXP 6480464 ciclopirox results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human ciguatoxin CTX1B affects expression ISO Mapt (Mus musculus) 6480464 Ciguatoxins affects the expression of MAPT mRNA CTD PMID:18353800 MAPT Human cilostazol multiple interactions ISO Mapt (Mus musculus) 6480464 cilostazol affects the acetylation of and affects the phosphorylation of MAPT protein and SIRT1 protein affects the reaction [cilostazol affects the acetylation of and affects the phosphorylation of MAPT protein] CTD PMID:24254769 MAPT Human citric acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Citric Acid CTD PMID:39172838 MAPT Human citric acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Citric Acid] CTD PMID:39172838 MAPT Human clotrimazole decreases expression ISO Mapt (Rattus norvegicus) 6480464 Clotrimazole results in decreased expression of MAPT mRNA CTD PMID:30047161 MAPT Human copper atom decreases expression ISO Mapt (Rattus norvegicus) 6480464 Copper results in decreased expression of MAPT mRNA CTD PMID:22465980 MAPT Human copper atom increases phosphorylation EXP 6480464 Copper results in increased phosphorylation of MAPT protein CTD PMID:25671100 MAPT Human copper atom multiple interactions ISO Mapt (Mus musculus) 6480464 Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX1 protein] and Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX2 protein] CTD PMID:25352456 MAPT Human copper atom multiple interactions EXP 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased phosphorylation of MAPT protein more ... CTD PMID:19122148 and PMID:25671100 MAPT Human copper(0) decreases expression ISO Mapt (Rattus norvegicus) 6480464 Copper results in decreased expression of MAPT mRNA CTD PMID:22465980 MAPT Human copper(0) increases phosphorylation EXP 6480464 Copper results in increased phosphorylation of MAPT protein CTD PMID:25671100 MAPT Human copper(0) multiple interactions ISO Mapt (Mus musculus) 6480464 Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX1 protein] and Copper promotes the reaction [[PSEN1 gene mutant form co-treated with APP gene mutant form co-treated with MAPT gene mutant form] results in decreased expression of CPLX2 protein] CTD PMID:25352456 MAPT Human copper(0) multiple interactions EXP 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased phosphorylation of MAPT protein more ... CTD PMID:19122148 and PMID:25671100 MAPT Human cordycepin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 cordycepin inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:30031108 MAPT Human cordycepin increases phosphorylation EXP 6480464 cordycepin results in increased phosphorylation of MAPT protein CTD PMID:33184027 MAPT Human coumarin affects phosphorylation EXP 6480464 coumarin affects the phosphorylation of MAPT protein CTD PMID:35688186 MAPT Human curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA] CTD PMID:31521693 MAPT Human cyclophosphamide multiple interactions EXP 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 MAPT Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of MAPT mRNA CTD PMID:20106945 and PMID:27989131 MAPT Human cypermethrin decreases expression ISO Mapt (Rattus norvegicus) 6480464 cypermethrin results in decreased expression of MAPT mRNA CTD PMID:22528246 MAPT Human cypermethrin increases expression ISO Mapt (Mus musculus) 6480464 cypermethrin results in increased expression of MAPT protein CTD PMID:26143737 MAPT Human D-aspartic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein more ... CTD PMID:30822420 MAPT Human D-aspartic acid increases cleavage ISO Mapt (Rattus norvegicus) 6480464 D-Aspartic Acid results in increased cleavage of MAPT protein CTD PMID:30822420 MAPT Human D-fructofuranose 1,6-bisphosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate CTD PMID:39172838 MAPT Human D-fructofuranose 1,6-bisphosphate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of fructose-1 more ... CTD PMID:39172838 MAPT Human D-fructofuranose 1,6-bisphosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate] CTD PMID:39172838 MAPT Human D-glucopyranose 6-phosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Glucose-6-Phosphate CTD PMID:39172838 MAPT Human D-glucopyranose 6-phosphate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glucose-6-Phosphate and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glucose-6-Phosphate] CTD PMID:39172838 MAPT Human D-glucopyranose 6-phosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Glucose-6-Phosphate] CTD PMID:39172838 MAPT Human D-glucose increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Glucose CTD PMID:39172838 MAPT Human D-glucose multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human D-glucose multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human daunorubicin decreases expression EXP 6480464 Daunorubicin results in decreased expression of MAPT mRNA and Daunorubicin results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human decabromodiphenyl ether increases expression ISO Mapt (Mus musculus) 6480464 decabromobiphenyl ether results in increased expression of MAPT protein CTD PMID:25194327 MAPT Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPT protein CTD PMID:35467087 MAPT Human diaziquone decreases expression EXP 6480464 diaziquone results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:16269432 MAPT Human dibutyl phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of MAPT mRNA CTD PMID:28302478 MAPT Human diethyl phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human diethylstilbestrol decreases expression ISO Mapt (Rattus norvegicus) 6480464 Diethylstilbestrol results in decreased expression of MAPT mRNA CTD PMID:17005392 MAPT Human dihydrolipoic acid multiple interactions EXP 6480464 dihydrolipoic acid inhibits the reaction [[Tretinoin co-treated with BDNF protein] results in increased expression of MAPT protein] and dihydrolipoic acid promotes the reaction [Aluminum Hydroxide inhibits the reaction [[Tretinoin co-treated with BDNF protein] results in increased expression of MAPT protein]] CTD PMID:37409350 MAPT Human dihydrolipoic acid decreases expression EXP 6480464 dihydrolipoic acid results in decreased expression of MAPT protein CTD PMID:37409350 MAPT Human diisobutyl phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human diisononyl phthalate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA CTD PMID:31199487 MAPT Human dioxygen multiple interactions ISO Mapt (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MAPT mRNA CTD PMID:30529165 MAPT Human dipicolinic acid multiple interactions EXP 6480464 dipicolinic acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 MAPT Human dizocilpine maleate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPT protein] CTD PMID:21976409 MAPT Human dizocilpine maleate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein] more ... CTD PMID:30822420 MAPT Human donepezil hydrochloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Donepezil inhibits the reaction [amyloid beta-protein (1-42) results in increased phosphorylation of MAPT protein] CTD PMID:36474082 MAPT Human dopamine multiple interactions EXP 6480464 Dopamine metabolite promotes the reaction [MAPT protein binds to MAPT protein] and Dopamine promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:16180106 MAPT Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:33124469 MAPT Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human doxorubicin multiple interactions EXP 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 MAPT Human elemental selenium multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 MAPT Human emetine decreases expression EXP 6480464 Emetine results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human emodin decreases expression EXP 6480464 Emodin results in decreased expression of MAPT mRNA CTD PMID:16045814 MAPT Human endosulfan affects expression ISO Mapt (Mus musculus) 6480464 Endosulfan affects the expression of MAPT protein CTD PMID:26143737 MAPT Human endosulfan decreases expression ISO Mapt (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of MAPT mRNA CTD PMID:29391264 MAPT Human ethanol increases phosphorylation ISO Mapt (Mus musculus) 6480464 Ethanol results in increased phosphorylation of MAPT protein CTD PMID:30143782 MAPT Human ethanol multiple interactions ISO Mapt (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of MAPT mRNA and Roscovitine inhibits the reaction [Ethanol results in increased phosphorylation of MAPT protein] CTD PMID:30143782 and PMID:30319688 MAPT Human ethylparaben decreases expression EXP 6480464 ethyl-p-hydroxybenzoate results in decreased expression of MAPT mRNA CTD PMID:37690743 MAPT Human fasudil multiple interactions ISO Mapt (Rattus norvegicus) 6480464 fasudil inhibits the reaction [methylmercuric chloride results in decreased expression of MAPT protein] CTD PMID:20869980 MAPT Human fenbendazole decreases expression EXP 6480464 Fenbendazole results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human fisetin multiple interactions ISO Mapt (Mus musculus) 6480464 fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] CTD PMID:31539617 MAPT Human folic acid multiple interactions ISO Mapt (Mus musculus) 6480464 Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BAD protein modified form] more ... CTD PMID:28422052 and PMID:29068127 MAPT Human folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of MAPT mRNA CTD PMID:21867686 MAPT Human folic acid decreases expression ISO Mapt (Mus musculus) 6480464 Folic Acid results in decreased expression of MAPT mRNA CTD PMID:25629700 MAPT Human formaldehyde multiple interactions EXP 6480464 Formaldehyde affects the reaction [MAPT protein binds to MAPT protein] and Formaldehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17241479 and PMID:17637844 MAPT Human Formyl-N-acetyl-5-methoxykynurenamine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] CTD PMID:31833155 MAPT Human FR900359 decreases phosphorylation EXP 6480464 FR900359 results in decreased phosphorylation of MAPT protein CTD PMID:37730182 MAPT Human fructose decreases expression ISO Mapt (Rattus norvegicus) 6480464 Fructose results in decreased expression of MAPT protein CTD PMID:37121297 MAPT Human fulvestrant decreases expression EXP 6480464 fulvestrant results in decreased expression of MAPT protein CTD PMID:20579400 MAPT Human fumaric acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of fumaric acid] CTD PMID:39172838 MAPT Human fumaric acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of fumaric acid CTD PMID:39172838 MAPT Human galactose increases expression ISO Mapt (Mus musculus) 6480464 Galactose results in increased expression of MAPT protein CTD PMID:36878094 MAPT Human galactose multiple interactions ISO Mapt (Mus musculus) 6480464 gentiopicroside analog inhibits the reaction [Galactose results in increased expression of MAPT protein] CTD PMID:36878094 MAPT Human genistein multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of MAPT gene CTD PMID:28505145 MAPT Human gentamycin decreases expression ISO Mapt (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of MAPT mRNA CTD PMID:33387578 MAPT Human Gentiopicrin multiple interactions ISO Mapt (Mus musculus) 6480464 gentiopicroside analog inhibits the reaction [Galactose results in increased expression of MAPT protein] CTD PMID:36878094 MAPT Human glucose multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human glucose multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Glucose] CTD PMID:39172838 MAPT Human glucose increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Glucose CTD PMID:39172838 MAPT Human glyceraldehyde 3-phosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Glyceraldehyde 3-Phosphate CTD PMID:39172838 MAPT Human glyceraldehyde 3-phosphate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glyceraldehyde 3-Phosphate and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Glyceraldehyde 3-Phosphate] CTD PMID:39172838 MAPT Human glyceraldehyde 3-phosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Glyceraldehyde 3-Phosphate] CTD PMID:39172838 MAPT Human glycerol 1-phosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid] CTD PMID:39172838 MAPT Human glycerol 1-phosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of alpha-glycerophosphoric acid CTD PMID:39172838 MAPT Human glyoxal multiple interactions ISO Mapt (Mus musculus) 6480464 Glyoxal promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 MAPT Human griseofulvin increases expression ISO Mapt (Mus musculus) 6480464 Griseofulvin results in increased expression of MAPT mRNA more ... CTD PMID:10051481 MAPT Human harmine multiple interactions EXP 6480464 Harmine inhibits the reaction [DYRK1A protein results in increased phosphorylation of MAPT protein] CTD PMID:21573099 MAPT Human heparin multiple interactions EXP 6480464 Heparin promotes the reaction [MAPT protein binds to MAPT protein] and Mercuric Chloride promotes the reaction [Heparin promotes the reaction [MAPT protein binds to MAPT protein]] CTD PMID:20665688 and PMID:31678113 MAPT Human hydrogen peroxide multiple interactions EXP 6480464 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA] more ... CTD PMID:28526263 more ... MAPT Human hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of MAPT mRNA CTD PMID:31521693 MAPT Human hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPT protein CTD PMID:31173752 MAPT Human IMP affects abundance EXP 6480464 MAPT protein mutant form affects the abundance of Inosine Monophosphate CTD PMID:39172838 MAPT Human IMP multiple interactions EXP 6480464 PF-06840003 affects the reaction [MAPT protein mutant form affects the abundance of Inosine Monophosphate] CTD PMID:39172838 MAPT Human indole-3-methanol affects expression ISO Mapt (Rattus norvegicus) 6480464 indole-3-carbinol affects the expression of MAPT mRNA CTD PMID:21396975 MAPT Human ionomycin decreases phosphorylation ISO Mapt (Mus musculus) 6480464 Ionomycin results in decreased phosphorylation of MAPT protein CTD PMID:9200503 MAPT Human ionomycin decreases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Ionomycin results in decreased phosphorylation of MAPT protein CTD PMID:9200503 MAPT Human ionomycin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 MAPT Human ionomycin multiple interactions ISO Mapt (Mus musculus) 6480464 Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 MAPT Human iron(2+) sulfate (anhydrous) multiple interactions ISO Mapt (Rattus norvegicus) 6480464 (22R more ... CTD PMID:19850110 MAPT Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of MAPT protein CTD PMID:32959892 MAPT Human ketamine increases phosphorylation ISO Mapt (Mus musculus) 6480464 Ketamine results in increased phosphorylation of MAPT protein CTD PMID:20093173 and PMID:31470060 MAPT Human ketamine multiple interactions ISO Mapt (Mus musculus) 6480464 MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein] and MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein] CTD PMID:31470060 MAPT Human keto-D-fructose 1,6-bisphosphate multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate] CTD PMID:39172838 MAPT Human keto-D-fructose 1,6-bisphosphate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of fructose-1 more ... CTD PMID:39172838 MAPT Human keto-D-fructose 1,6-bisphosphate decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of fructose-1 and 6-diphosphate CTD PMID:39172838 MAPT Human kynurenine increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Kynurenine CTD PMID:39172838 MAPT Human kynurenine multiple interactions EXP 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Kynurenine more ... CTD PMID:39172838 MAPT Human kynurenine multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Kynurenine and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in increased abundance of Kynurenine] CTD PMID:39172838 MAPT Human L-arginine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Arginine] CTD PMID:39172838 MAPT Human L-arginine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Arginine CTD PMID:39172838 MAPT Human L-ascorbic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:24142891 MAPT Human L-aspartic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Aspartic Acid] CTD PMID:39172838 MAPT Human L-aspartic acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Aspartic Acid CTD PMID:39172838 MAPT Human L-cysteine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Cysteine] CTD PMID:39172838 MAPT Human L-cysteine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Cysteine CTD PMID:39172838 MAPT Human L-isoleucine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Isoleucine] CTD PMID:39172838 MAPT Human L-isoleucine increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Isoleucine CTD PMID:39172838 MAPT Human L-lysine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Lysine CTD PMID:39172838 MAPT Human L-lysine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Lysine] CTD PMID:39172838 MAPT Human L-phenylalanine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Phenylalanine CTD PMID:39172838 MAPT Human L-phenylalanine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Phenylalanine] CTD PMID:39172838 MAPT Human L-serine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] and Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased phosphorylation of MAPT protein] CTD PMID:30476904 MAPT Human L-tryptophan multiple interactions EXP 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Tryptophan and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Tryptophan] CTD PMID:39172838 MAPT Human L-tryptophan multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Tryptophan CTD PMID:39172838 MAPT Human lansoprazole affects binding EXP 6480464 Lansoprazole binds to MAPT protein alternative form CTD PMID:20110603 MAPT Human lasalocid decreases expression EXP 6480464 Lasalocid results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human lead diacetate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 lead acetate results in decreased expression of and results in increased phosphorylation of MAPT protein more ... CTD PMID:23134599 more ... MAPT Human lead diacetate multiple interactions EXP 6480464 lead acetate results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:27293183 MAPT Human lead diacetate increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 lead acetate results in increased phosphorylation of MAPT protein CTD PMID:22811615 and PMID:25088297 MAPT Human lead diacetate multiple interactions ISO Mapt (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein more ... CTD PMID:24954411 more ... MAPT Human lead diacetate increases expression ISO Mapt (Mus musculus) 6480464 lead acetate results in increased expression of MAPT mRNA CTD PMID:24954411 MAPT Human lead tetraacetate decreases expression ISO Mapt (Mus musculus) 6480464 lead tetraacetate results in decreased expression of MAPT mRNA CTD PMID:20865013 MAPT Human lead(0) affects phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Lead affects the phosphorylation of MAPT protein CTD PMID:22342405 MAPT Human lead(0) multiple interactions ISO Mapt (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein and fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] CTD PMID:31539617 more ... MAPT Human lead(0) increases phosphorylation ISO Mapt (Mus musculus) 6480464 Lead results in increased phosphorylation of MAPT protein CTD PMID:31539617 MAPT Human leflunomide increases expression EXP 6480464 leflunomide results in increased expression of MAPT mRNA CTD PMID:28988120 MAPT Human lipoic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in increased phosphorylation of MAPT protein] CTD PMID:34133789 MAPT Human liraglutide multiple interactions EXP 6480464 Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein] and Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]] CTD PMID:31173752 MAPT Human lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 MAPT Human lithium chloride multiple interactions ISO Mapt (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]] and Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein] CTD PMID:27050422 MAPT Human lithium chloride decreases expression EXP 6480464 Lithium Chloride results in decreased expression of MAPT mRNA CTD PMID:23527032 MAPT Human lithium chloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein] and Lithium Chloride inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPT protein] CTD PMID:20937724 and PMID:35993674 MAPT Human lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 MAPT Human losartan multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Losartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:22982863 MAPT Human LY294002 multiple interactions ISO Mapt (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]] CTD PMID:27050422 MAPT Human malic acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of malic acid CTD PMID:39172838 MAPT Human malic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of malic acid] CTD PMID:39172838 MAPT Human malonaldehyde multiple interactions ISO Mapt (Mus musculus) 6480464 Malondialdehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 MAPT Human maneb multiple interactions ISO Mapt (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA more ... CTD PMID:23963992 MAPT Human manganese(II) chloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein] more ... CTD PMID:20937724 MAPT Human manganese(II) chloride increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 manganese chloride results in increased phosphorylation of MAPT protein CTD PMID:20937724 MAPT Human mebendazole decreases expression EXP 6480464 Mebendazole results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human melatonin multiple interactions ISO Mapt (Mus musculus) 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA] and Melatonin inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 and PMID:23963992 MAPT Human melatonin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Aluminum Chloride results in increased expression of MAPT protein modified form] more ... CTD PMID:31833155 and PMID:35526705 MAPT Human melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPT protein] CTD PMID:10617124 MAPT Human mercury dichloride multiple interactions EXP 6480464 Melatonin inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPT protein] more ... CTD PMID:10617124 and PMID:20665688 MAPT Human mercury dichloride increases phosphorylation EXP 6480464 Mercuric Chloride results in increased phosphorylation of MAPT protein CTD PMID:10617124 MAPT Human methamphetamine multiple interactions ISO Mapt (Mus musculus) 6480464 (1R-(exo more ... CTD PMID:11756511 more ... MAPT Human methamphetamine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] CTD PMID:29705343 MAPT Human methamphetamine increases phosphorylation EXP 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29705343 and PMID:31270305 MAPT Human methamphetamine increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29705343 MAPT Human methamphetamine multiple interactions EXP 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] more ... CTD PMID:29705343 more ... MAPT Human methamphetamine increases phosphorylation ISO Mapt (Mus musculus) 6480464 Methamphetamine results in increased phosphorylation of MAPT protein CTD PMID:29981415 and PMID:38311184 MAPT Human methamphetamine increases expression ISO Mapt (Mus musculus) 6480464 Methamphetamine results in increased expression of MAPT mRNA and Methamphetamine results in increased expression of MAPT protein modified form CTD PMID:26307267 and PMID:32278788 MAPT Human methamphetamine decreases expression ISO Mapt (Mus musculus) 6480464 Methamphetamine results in decreased expression of MAPT mRNA CTD PMID:11756511 MAPT Human methimazole decreases expression ISO Mapt (Rattus norvegicus) 6480464 Methimazole results in decreased expression of MAPT mRNA CTD PMID:30047161 MAPT Human methylene blue decreases expression EXP 6480464 Methylene Blue results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human methylene blue multiple interactions ISO Mapt (Mus musculus) 6480464 [Methylene Blue co-treated with MAPT protein mutant form] affects the localization of NFE2L2 protein more ... CTD PMID:24556215 MAPT Human methylene blue decreases phosphorylation EXP 6480464 Methylene Blue results in decreased phosphorylation of MAPT protein modified form CTD PMID:24556215 MAPT Human methylene blue increases expression EXP 6480464 Methylene Blue results in increased expression of MAPT mRNA CTD PMID:16930453 MAPT Human methylglyoxal multiple interactions ISO Mapt (Mus musculus) 6480464 Pyruvaldehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 MAPT Human methylmercury chloride increases expression ISO Mapt (Mus musculus) 6480464 methylmercuric chloride results in increased expression of MAPT mRNA CTD PMID:20061341 MAPT Human methylmercury chloride increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 methylmercuric chloride results in increased phosphorylation of MAPT protein CTD PMID:28821999 MAPT Human methylmercury chloride decreases expression ISO Mapt (Rattus norvegicus) 6480464 methylmercuric chloride results in decreased expression of MAPT protein CTD PMID:20869980 MAPT Human methylmercury chloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 exoenzyme C3 more ... CTD PMID:20869980 MAPT Human methylseleninic acid decreases expression EXP 6480464 methylselenic acid results in decreased expression of MAPT mRNA CTD PMID:12517777 MAPT Human microcystin LF affects phosphorylation ISO Mapt (Mus musculus) 6480464 microcystin-LF affects the phosphorylation of MAPT protein CTD PMID:21934130 MAPT Human microcystin-LR affects phosphorylation ISO Mapt (Mus musculus) 6480464 cyanoginosin LR affects the phosphorylation of MAPT protein CTD PMID:21934130 MAPT Human microcystin-LR increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 cyanoginosin LR results in increased phosphorylation of MAPT protein CTD PMID:22000993 more ... MAPT Human microcystin-LR multiple interactions EXP 6480464 SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:23929704 MAPT Human microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of MAPT protein CTD PMID:23929704 and PMID:27393157 MAPT Human microcystin-LR multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] more ... CTD PMID:22000993 and PMID:24142891 MAPT Human microcystin-LR increases localization ISO Mapt (Rattus norvegicus) 6480464 cyanoginosin LR results in increased localization of MAPT protein CTD PMID:22000993 MAPT Human mono(2-ethylhexyl) phthalate increases expression ISO Mapt (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of MAPT mRNA CTD PMID:22401849 MAPT Human morphine increases expression ISO Mapt (Rattus norvegicus) 6480464 Morphine results in increased expression of MAPT mRNA CTD PMID:15183518 MAPT Human Morroniside multiple interactions EXP 6480464 morroniside inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:26836014 MAPT Human mycophenolic acid decreases expression EXP 6480464 Mycophenolic Acid results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human N-acetyl-L-cysteine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:24142891 MAPT Human N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [1 and 2-diacetylbenzene results in increased phosphorylation of MAPT protein] CTD PMID:28734998 MAPT Human N-methyl-4-phenylpyridinium increases expression ISO Mapt (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPT mRNA CTD PMID:26558463 MAPT Human N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPT protein alternative form CTD PMID:25402454 MAPT Human N-methyl-4-phenylpyridinium increases splicing EXP 6480464 1-Methyl-4-phenylpyridinium results in increased splicing of MAPT mRNA CTD PMID:25402454 MAPT Human N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 SRSF2 promotes the reaction [1-Methyl-4-phenylpyridinium results in increased splicing of MAPT mRNA] CTD PMID:25402454 MAPT Human N-methyl-4-phenylpyridinium affects localization ISO Mapt (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium affects the localization of MAPT protein CTD PMID:17634376 MAPT Human N-methyl-D-aspartic acid multiple interactions ISO Mapt (Mus musculus) 6480464 N-Methylaspartate inhibits the reaction [gelsenicine results in increased phosphorylation of MAPT protein] CTD PMID:34389372 MAPT Human N-nitrosodiethylamine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA and Diethylnitrosamine results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:18164116 more ... MAPT Human N-phosphocreatine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Phosphocreatine] CTD PMID:39172838 MAPT Human N-phosphocreatine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Phosphocreatine CTD PMID:39172838 MAPT Human nickel atom decreases expression ISO Mapt (Mus musculus) 6480464 Nickel results in decreased expression of MAPT mRNA CTD PMID:12540486 MAPT Human nickel atom multiple interactions EXP 6480464 Nickel results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:31953414 MAPT Human nickel atom increases response to substance EXP 6480464 MAPT protein mutant form results in increased susceptibility to Nickel CTD PMID:31953414 MAPT Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of MAPT mRNA CTD PMID:24768652 and PMID:25583101 MAPT Human nickel sulfate decreases expression ISO Mapt (Mus musculus) 6480464 nickel sulfate results in decreased expression of MAPT mRNA CTD PMID:16100012 MAPT Human niclosamide increases expression EXP 6480464 Niclosamide results in increased expression of MAPT mRNA CTD PMID:36318118 MAPT Human nocodazole decreases expression EXP 6480464 Nocodazole results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human norethisterone decreases expression EXP 6480464 Norethindrone results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human O-phosphoserine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Phosphoserine] CTD PMID:39172838 MAPT Human O-phosphoserine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Phosphoserine CTD PMID:39172838 MAPT Human O-propanoyl-L-carnitine decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of propionylcarnitine CTD PMID:39172838 MAPT Human O-propanoyl-L-carnitine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of propionylcarnitine] CTD PMID:39172838 MAPT Human okadaic acid affects phosphorylation ISO Mapt (Mus musculus) 6480464 Okadaic Acid affects the phosphorylation of MAPT protein CTD PMID:21934130 and PMID:27050422 MAPT Human okadaic acid increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Okadaic Acid results in increased phosphorylation of MAPT protein CTD PMID:26732598 and PMID:7723735 MAPT Human okadaic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein more ... CTD PMID:7723735 and PMID:9200503 MAPT Human okadaic acid increases phosphorylation EXP 6480464 Okadaic Acid results in increased phosphorylation of MAPT protein CTD PMID:21715663 more ... MAPT Human okadaic acid multiple interactions EXP 6480464 [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] more ... CTD PMID:21715663 more ... MAPT Human okadaic acid multiple interactions ISO Mapt (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]] more ... CTD PMID:27050422 and PMID:9200503 MAPT Human oxaliplatin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MAPT mRNA CTD PMID:25729387 MAPT Human oxaliplatin decreases expression ISO Mapt (Rattus norvegicus) 6480464 oxaliplatin results in decreased expression of MAPT mRNA CTD PMID:25729387 MAPT Human oxidopamine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Oxidopamine results in increased cleavage of and results in decreased phosphorylation of MAPT protein CTD PMID:12686375 MAPT Human ozone decreases expression ISO Mapt (Mus musculus) 6480464 Ozone results in decreased expression of MAPT mRNA CTD PMID:12763052 MAPT Human ozone multiple interactions ISO Mapt (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of MAPT mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MAPT mRNA CTD PMID:27106289 and PMID:34911549 MAPT Human paclitaxel multiple interactions EXP 6480464 MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 MAPT Human paclitaxel multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Paclitaxel inhibits the reaction [annonacin affects the localization of MAPT protein] CTD PMID:17634376 MAPT Human paclitaxel decreases expression EXP 6480464 Paclitaxel results in decreased expression of MAPT mRNA and Paclitaxel results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human paracetamol affects expression ISO Mapt (Mus musculus) 6480464 Acetaminophen affects the expression of MAPT mRNA CTD PMID:17562736 MAPT Human paraquat multiple interactions ISO Mapt (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA more ... CTD PMID:22292029 and PMID:23963992 MAPT Human paraquat increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Paraquat results in increased phosphorylation of MAPT protein CTD PMID:31715309 and PMID:32738378 MAPT Human paraquat multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased phosphorylation of MAPT protein] more ... CTD PMID:31715309 and PMID:32738378 MAPT Human paraquat decreases expression ISO Mapt (Rattus norvegicus) 6480464 Paraquat results in decreased expression of MAPT protein CTD PMID:24521700 MAPT Human pentachlorophenol increases expression ISO Mapt (Mus musculus) 6480464 Pentachlorophenol results in increased expression of MAPT mRNA CTD PMID:23892564 MAPT Human pentanal increases expression EXP 6480464 pentanal results in increased expression of MAPT mRNA CTD PMID:26079696 MAPT Human pentetrazol increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Pentylenetetrazole results in increased phosphorylation of MAPT protein CTD PMID:32653415 MAPT Human pentetrazol multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Sitagliptin Phosphate inhibits the reaction [Pentylenetetrazole results in increased phosphorylation of MAPT protein] CTD PMID:32653415 MAPT Human perfluorooctane-1-sulfonic acid increases expression ISO Mapt (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of MAPT protein CTD PMID:19211617 MAPT Human perfluorooctane-1-sulfonic acid increases expression ISO Mapt (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of MAPT mRNA CTD PMID:27018931 MAPT Human perfluorooctane-1-sulfonic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of and results in increased phosphorylation of MAPT protein CTD PMID:27018931 MAPT Human perfluorooctanoic acid increases expression ISO Mapt (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of MAPT protein CTD PMID:19211617 MAPT Human phenylarsine oxide multiple interactions EXP 6480464 [oxophenylarsine results in increased activity of MARK1 protein] which results in increased phosphorylation of MAPT protein and Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 MAPT Human phenylarsine oxide multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 MAPT Human phenylarsine oxide increases phosphorylation EXP 6480464 oxophenylarsine results in increased phosphorylation of MAPT protein CTD PMID:10737602 MAPT Human phenylarsine oxide increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 oxophenylarsine results in increased phosphorylation of MAPT protein CTD PMID:10737602 MAPT Human PhIP increases expression ISO Mapt (Mus musculus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of MAPT protein modified form CTD PMID:32169473 MAPT Human phosgene affects expression ISO Mapt (Mus musculus) 6480464 Phosgene affects the expression of MAPT mRNA CTD PMID:16300373 MAPT Human phosphoenolpyruvate multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate] CTD PMID:39172838 MAPT Human picoxystrobin decreases expression EXP 6480464 picoxystrobin results in decreased expression of MAPT mRNA CTD PMID:33512557 MAPT Human piericidin A increases response to substance ISO Mapt (Mus musculus) 6480464 MAPT protein polymorphism results in increased susceptibility to piericidin A CTD PMID:25437199 MAPT Human piericidin A increases phosphorylation ISO Mapt (Mus musculus) 6480464 piericidin A results in increased phosphorylation of MAPT protein polymorphism CTD PMID:25437199 MAPT Human pirinixic acid decreases expression ISO Mapt (Mus musculus) 6480464 pirinixic acid results in decreased expression of MAPT mRNA CTD PMID:23811191 MAPT Human PNU-282987 multiple interactions EXP 6480464 [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:21715663 MAPT Human podophyllotoxin decreases expression EXP 6480464 Podophyllotoxin results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human potassium chloride multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Okadaic Acid inhibits the reaction [Potassium Chloride results in decreased phosphorylation of MAPT protein] CTD PMID:9200503 MAPT Human potassium chloride decreases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Potassium Chloride results in decreased phosphorylation of MAPT protein CTD PMID:9200503 MAPT Human pravastatin decreases expression ISO Mapt (Rattus norvegicus) 6480464 Pravastatin results in decreased expression of MAPT mRNA CTD PMID:27225895 MAPT Human pravastatin decreases expression ISO Mapt (Mus musculus) 6480464 Pravastatin results in decreased expression of MAPT mRNA CTD PMID:27225895 MAPT Human pravastatin affects expression EXP 6480464 Pravastatin affects the expression of MAPT CTD PMID:19461118 MAPT Human proanthocyanidin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPT protein] CTD PMID:25088297 MAPT Human progesterone increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Progesterone results in increased phosphorylation of MAPT protein CTD PMID:17443805 MAPT Human progesterone decreases expression ISO Mapt (Rattus norvegicus) 6480464 Progesterone results in decreased expression of MAPT protein CTD PMID:17443805 MAPT Human propanal increases expression EXP 6480464 propionaldehyde results in increased expression of MAPT mRNA CTD PMID:26079696 MAPT Human pyrithione multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein and GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 MAPT Human pyrrolidine dithiocarbamate decreases phosphorylation ISO Mapt (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein CTD PMID:17409235 MAPT Human pyruvic acid multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Pyruvic Acid and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Pyruvic Acid] CTD PMID:39172838 MAPT Human quercetin multiple interactions ISO Mapt (Mus musculus) 6480464 Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein] CTD PMID:27050422 MAPT Human quercetin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [aluminum lactate results in increased phosphorylation of MAPT protein] CTD PMID:26493151 MAPT Human quinolinic acid multiple interactions EXP 6480464 Quinolinic Acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 MAPT Human rac-lactic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Lactic Acid] CTD PMID:39172838 MAPT Human rac-lactic acid multiple interactions ISO Mapt (Mus musculus) 6480464 [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Lactic Acid and PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Lactic Acid] CTD PMID:39172838 MAPT Human rac-lactic acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Lactic Acid CTD PMID:39172838 MAPT Human resveratrol multiple interactions ISO Mapt (Mus musculus) 6480464 resveratrol affects the acetylation of and affects the phosphorylation of MAPT protein CTD PMID:24254769 MAPT Human resveratrol multiple interactions ISO Mapt (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [APP protein modified form results in increased expression of MAPT protein modified form] and resveratrol inhibits the reaction [APP protein modified form results in increased expression of MAPT protein] CTD PMID:25654502 MAPT Human resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of MAPT mRNA CTD PMID:12569576 MAPT Human resveratrol decreases phosphorylation ISO Mapt (Mus musculus) 6480464 resveratrol results in decreased phosphorylation of MAPT protein CTD PMID:23129026 MAPT Human resveratrol increases expression ISO Mapt (Mus musculus) 6480464 resveratrol results in increased expression of MAPT mRNA CTD PMID:22610192 MAPT Human Ro 31-8220 multiple interactions EXP 6480464 Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] CTD PMID:12605413 MAPT Human rotenone increases expression ISO Mapt (Rattus norvegicus) 6480464 Rotenone results in increased expression of MAPT protein CTD PMID:16219024 MAPT Human rotenone increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Rotenone results in increased phosphorylation of MAPT protein CTD PMID:16219024 MAPT Human rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of MAPT protein CTD PMID:16930453 MAPT Human S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 (22R more ... CTD PMID:19850110 MAPT Human sarin decreases expression EXP 6480464 Sarin results in decreased expression of MAPT mRNA CTD PMID:19522546 MAPT Human SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] and SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:12605413 and PMID:23929704 MAPT Human SB 203580 multiple interactions ISO Mapt (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [cyanoginosin LR results in increased localization of MAPT protein] and SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:22000993 MAPT Human SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAPT mRNA CTD PMID:27188386 MAPT Human scopolamine decreases expression ISO Mapt (Rattus norvegicus) 6480464 Scopolamine results in decreased expression of MAPT mRNA CTD PMID:12818353 MAPT Human selenium atom multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form] CTD PMID:30695686 MAPT Human serpentine asbestos decreases expression ISO Mapt (Mus musculus) 6480464 Asbestos and Serpentine results in decreased expression of MAPT mRNA CTD PMID:16251409 MAPT Human sertraline multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Sertraline results in decreased expression of and results in decreased cleavage of MAPT protein] more ... CTD PMID:33124469 MAPT Human sevoflurane increases phosphorylation ISO Mapt (Mus musculus) 6480464 Sevoflurane results in increased phosphorylation of MAPT protein CTD PMID:35575159 MAPT Human sevoflurane multiple interactions ISO Mapt (Mus musculus) 6480464 APOE protein alternative form inhibits the reaction [Sevoflurane results in increased phosphorylation of MAPT protein] CTD PMID:35575159 MAPT Human silicon dioxide increases phosphorylation ISO Mapt (Mus musculus) 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPT protein CTD PMID:24831964 MAPT Human silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPT protein CTD PMID:24831964 MAPT Human silver atom increases expression EXP 6480464 Silver results in increased expression of MAPT protein modified form CTD PMID:27593553 MAPT Human silver atom decreases expression EXP 6480464 Silver results in decreased expression of MAPT protein CTD PMID:27593553 MAPT Human silver(0) increases expression EXP 6480464 Silver results in increased expression of MAPT protein modified form CTD PMID:27593553 MAPT Human silver(0) decreases expression EXP 6480464 Silver results in decreased expression of MAPT protein CTD PMID:27593553 MAPT Human simvastatin affects expression EXP 6480464 Simvastatin affects the expression of MAPT CTD PMID:19461118 MAPT Human sirolimus multiple interactions EXP 6480464 Sirolimus results in decreased expression of and results in decreased cleavage of MAPT protein CTD PMID:33124469 MAPT Human sodium arsenate decreases expression ISO Mapt (Mus musculus) 6480464 sodium arsenate results in decreased expression of MAPT mRNA CTD PMID:21795629 MAPT Human sodium arsenite decreases expression ISO Mapt (Mus musculus) 6480464 sodium arsenite results in decreased expression of MAPT mRNA CTD PMID:23022324 MAPT Human sodium arsenite multiple interactions ISO Mapt (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 MAPT Human sodium arsenite affects methylation EXP 6480464 sodium arsenite affects the methylation of MAPT gene CTD PMID:28589171 MAPT Human sodium arsenite increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 sodium arsenite results in increased phosphorylation of MAPT protein CTD PMID:18674524 MAPT Human Soman decreases expression ISO Mapt (Rattus norvegicus) 6480464 Soman results in decreased expression of MAPT mRNA CTD PMID:19281266 MAPT Human staurosporine multiple interactions EXP 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 MAPT Human staurosporine multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] CTD PMID:10737602 MAPT Human streptozocin increases phosphorylation ISO Mapt (Mus musculus) 6480464 Streptozocin results in increased phosphorylation of MAPT protein CTD PMID:20976160 and PMID:28422052 MAPT Human streptozocin increases expression ISO Mapt (Mus musculus) 6480464 Streptozocin results in increased expression of MAPT protein modified form CTD PMID:34428446 MAPT Human streptozocin multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] more ... CTD PMID:31833155 MAPT Human streptozocin increases phosphorylation ISO Mapt (Rattus norvegicus) 6480464 Streptozocin results in increased phosphorylation of MAPT protein CTD PMID:31833155 MAPT Human streptozocin multiple interactions ISO Mapt (Mus musculus) 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] more ... CTD PMID:20976160 more ... MAPT Human succinic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Succinic Acid] CTD PMID:39172838 MAPT Human succinic acid decreases abundance EXP 6480464 MAPT protein mutant form results in decreased abundance of Succinic Acid CTD PMID:39172838 MAPT Human sulfadimethoxine decreases expression ISO Mapt (Rattus norvegicus) 6480464 Sulfadimethoxine results in decreased expression of MAPT mRNA CTD PMID:30047161 MAPT Human sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of MAPT mRNA CTD PMID:31533062 MAPT Human tadalafil multiple interactions ISO Mapt (Mus musculus) 6480464 Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] CTD PMID:34428446 MAPT Human tamoxifen multiple interactions EXP 6480464 Tamoxifen inhibits the reaction [Estradiol results in increased expression of MAPT protein] CTD PMID:20579400 MAPT Human tamoxifen affects expression ISO Mapt (Mus musculus) 6480464 Tamoxifen affects the expression of MAPT mRNA CTD PMID:17555576 MAPT Human tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of MAPT protein CTD PMID:20579400 MAPT Human tauroursodeoxycholic acid multiple interactions ISO Mapt (Rattus norvegicus) 6480464 ursodoxicoltaurine inhibits the reaction [[APP protein modified form results in increased activity of CASP3 protein] which results in increased cleavage of MAPT protein] CTD PMID:18368144 MAPT Human tebufenpyrad decreases expression EXP 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of MAPT mRNA CTD PMID:33512557 MAPT Human testosterone enanthate affects expression EXP 6480464 testosterone enanthate affects the expression of MAPT mRNA CTD PMID:17440010 MAPT Human tetrachloromethane affects expression ISO Mapt (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of MAPT mRNA CTD PMID:17484886 MAPT Human tetrachloromethane decreases expression ISO Mapt (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of MAPT mRNA CTD PMID:16644059 MAPT Human tetrathiomolybdate(2-) multiple interactions EXP 6480464 tetrathiomolybdate inhibits the reaction [Copper results in increased phosphorylation of MAPT protein] CTD PMID:25671100 MAPT Human thapsigargin decreases expression ISO Mapt (Rattus norvegicus) 6480464 Thapsigargin results in decreased expression of MAPT protein CTD PMID:35544339 MAPT Human threonic acid multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of threonic acid] CTD PMID:39172838 MAPT Human threonic acid increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of threonic acid CTD PMID:39172838 MAPT Human titanium dioxide decreases expression ISO Mapt (Mus musculus) 6480464 titanium dioxide results in decreased expression of MAPT mRNA CTD PMID:23557971 more ... MAPT Human titanium dioxide increases methylation ISO Mapt (Mus musculus) 6480464 titanium dioxide results in increased methylation of MAPT gene CTD PMID:35295148 MAPT Human titanium dioxide decreases methylation ISO Mapt (Mus musculus) 6480464 titanium dioxide results in decreased methylation of MAPT gene and titanium dioxide results in decreased methylation of MAPT promoter CTD PMID:35295148 MAPT Human titanium dioxide decreases expression ISO Mapt (Rattus norvegicus) 6480464 titanium dioxide results in decreased expression of MAPT mRNA CTD PMID:30012374 MAPT Human tolonium chloride multiple interactions ISO Mapt (Mus musculus) 6480464 Tolonium Chloride results in decreased expression of and results in decreased phosphorylation of MAPT protein CTD PMID:36027949 MAPT Human topotecan multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MAPT mRNA CTD PMID:25729387 MAPT Human tributylstannane increases degradation ISO Mapt (Mus musculus) 6480464 tributyltin results in increased degradation of MAPT protein CTD PMID:33481012 MAPT Human tributylstannane increases cleavage ISO Mapt (Rattus norvegicus) 6480464 tributyltin results in increased cleavage of MAPT protein CTD PMID:23743147 MAPT Human tributylstannane multiple interactions ISO Mapt (Mus musculus) 6480464 CAST protein inhibits the reaction [tributyltin results in increased degradation of MAPT protein] CTD PMID:33481012 MAPT Human trichloroethene decreases expression ISO Mapt (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of MAPT mRNA CTD PMID:33387578 MAPT Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of MAPT mRNA CTD PMID:24935251 MAPT Human troglitazone decreases expression ISO Mapt (Mus musculus) 6480464 troglitazone results in decreased expression of MAPT mRNA CTD PMID:28973697 MAPT Human Tryptanthrine increases expression EXP 6480464 tryptanthrine results in increased expression of MAPT mRNA CTD PMID:23500671 MAPT Human valine multiple interactions EXP 6480464 PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Valine] CTD PMID:39172838 MAPT Human valine increases abundance EXP 6480464 MAPT protein mutant form results in increased abundance of Valine CTD PMID:39172838 MAPT Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of MAPT mRNA CTD PMID:25979313 MAPT Human valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAPT mRNA CTD PMID:27188386 MAPT Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of MAPT and Valproic Acid results in increased expression of MAPT mRNA CTD PMID:19101580 more ... MAPT Human valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of MAPT gene CTD PMID:29154799 MAPT Human vancomycin increases expression ISO Mapt (Mus musculus) 6480464 Vancomycin results in increased expression of MAPT mRNA CTD PMID:18930951 MAPT Human vinclozolin increases expression ISO Mapt (Rattus norvegicus) 6480464 vinclozolin results in increased expression of MAPT mRNA CTD PMID:23034163 MAPT Human vitamin E multiple interactions ISO Mapt (Mus musculus) 6480464 Vitamin E inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 MAPT Human WIN 55212-2 increases expression ISO Mapt (Mus musculus) 6480464 (3R)-((2 more ... CTD PMID:12237329 MAPT Human wortmannin increases phosphorylation ISO Mapt (Mus musculus) 6480464 wortmannin results in increased phosphorylation of MAPT protein CTD PMID:15842767 MAPT Human wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPT protein]] CTD PMID:31173752 MAPT Human wortmannin multiple interactions ISO Mapt (Mus musculus) 6480464 Melatonin inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] and Vitamin E inhibits the reaction [wortmannin results in increased phosphorylation of MAPT protein] CTD PMID:15842767 MAPT Human Y-27632 multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Y 27632 inhibits the reaction [methylmercuric chloride results in decreased expression of MAPT protein] CTD PMID:20869980 MAPT Human zaragozic acid A decreases expression ISO Mapt (Mus musculus) 6480464 squalestatin 1 results in decreased expression of MAPT mRNA CTD PMID:27225895 MAPT Human zaragozic acid A increases expression ISO Mapt (Rattus norvegicus) 6480464 squalestatin 1 results in increased expression of MAPT mRNA CTD PMID:27225895 MAPT Human zinc acetate multiple interactions EXP 6480464 [Zinc Acetate results in decreased abundance of Copper] which results in decreased phosphorylation of MAPT protein CTD PMID:25671100 MAPT Human zinc atom multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein and GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 MAPT Human zinc sulfate multiple interactions ISO Mapt (Rattus norvegicus) 6480464 Melatonin promotes the reaction [Zinc Sulfate inhibits the reaction [Aluminum Chloride results in increased expression of MAPT protein modified form]] more ... CTD PMID:35526705 MAPT Human zinc(0) multiple interactions ISO Mapt (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein and GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228
