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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phenolic donor
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Accession:CHEBI:139520 term browser browse the term
Definition:Any phenol that acts as an electron donor.
Synonyms:related_synonym: Formula=C6H5OR;   SMILES=OC1=CC=C([*])C=C1;   a phenolic donor;   phenolic donors
 xref: MetaCyc:Phenolic-Donors;   PMID:16098794


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1-naphthol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO [1-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor multiple interactions EXP 1-naphthol inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases abundance ISO CYP1A1 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases abundance
affects binding
decreases activity		 ISO CYP1A2 protein results in increased abundance of 1-naphthol
1-naphthol binds to CYP1A2 protein
1-naphthol results in decreased activity of CYP1A2 protein		 CTD PMID:15916432 PMID:16243959 PMID:32278787 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases abundance
multiple interactions		 ISO CYP1B1 protein results in increased abundance of 1-naphthol
[1-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA		 CTD PMID:16243959 PMID:27837168 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases abundance
multiple interactions		 ISO CYP2A13 protein results in increased abundance of 1-naphthol
[CYP2A13 protein results in increased oxidation of naphthalene] which results in increased abundance of 1-naphthol		 CTD PMID:27137136 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases abundance ISO CYP2B6 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases abundance ISO CYP2C19 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases abundance ISO CYP2C8 protein results in increased abundance of 1-naphthol CTD PMID:16243959
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases abundance ISO CYP2D6 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases abundance ISO CYP2E1 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases abundance ISO CYP3A4 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases abundance ISO CYP3A5 protein results in increased abundance of 1-naphthol CTD PMID:16243959 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions		 ISO ESR2 protein binds to 1-naphthol
1-naphthol inhibits the reaction [ESR2 protein binds to Estradiol]		 CTD PMID:22989670 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO 1-naphthol results in decreased expression of JAG1 mRNA CTD PMID:22989670 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity EXP 1-naphthol results in increased activity of NR1I2 protein CTD PMID:27665777 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity EXP 1-naphthol results in increased activity of NR1I3 protein CTD PMID:27665777 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO 1-naphthol results in increased expression of NRIP1 mRNA CTD PMID:22989670 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity EXP 1-naphthol results in increased activity of PPARA protein CTD PMID:27665777 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of 1-naphthol CTD PMID:15684482 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 1-naphthol binds to and results in decreased activity of THRB protein CTD PMID:18584933 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 1-naphthol analog results in increased activity of TRPA1 protein CTD PMID:29658714 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO 1-naphthol analog results in increased activity of TRPV3 protein CTD PMID:29658714 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases metabolic processing
multiple interactions
increases glucuronidation
affects metabolic processing		 EXP
ISO		 UGT1A6 protein results in increased metabolism of 1-naphthol
beta-Naphthoflavone promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]; Diclofenac inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]; Indomethacin inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]
Methylcholanthrene promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]; Paraquat promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]
UGT1A6 gene polymorphism affects the metabolism of 1-naphthol; UGT1A6 protein affects the metabolism of 1-naphthol		 CTD PMID:7646562 PMID:9429234 PMID:12153725 PMID:12756209 PMID:15336321 More... NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases glucuronidation EXP UGT1A7 protein results in increased glucuronidation of 1-naphthol; UGT1A8 protein results in increased glucuronidation of 1-naphthol CTD PMID:15502008 PMID:22846377 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 1-naphthol CTD PMID:15044611 PMID:18816295 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases glucuronidation ISO UGT2A1 protein results in increased glucuronidation of 1-naphthol CTD PMID:21164388 NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of 1-naphthol CTD PMID:8302279 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of 1-naphthol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589 		JBrowse link
2-naphthol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects sulfation ISO ABCC1 protein affects the sulfation of 2-naphthol CTD PMID:14742140 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [2-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor multiple interactions EXP 2-naphthol inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ces1d carboxylesterase 1D affects metabolic processing ISO CES1 protein affects the metabolism of 2-naphthol CTD PMID:12837533 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases abundance ISO CYP1A1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases abundance
affects binding
decreases activity		 ISO CYP1A2 protein results in increased abundance of 2-naphthol
2-naphthol binds to CYP1A2 protein
2-naphthol results in decreased activity of CYP1A2 protein		 CTD PMID:15916432 PMID:16243959 PMID:32278787 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [2-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases abundance ISO CYP2B6 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases abundance ISO CYP2E1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases abundance ISO CYP3A4 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Sult4a1 sulfotransferase family 4A, member 1 increases metabolic processing ISO SULT4A1 protein results in increased metabolism of 2-naphthol CTD PMID:12039030 NCBI chr 7:115,216,066...115,240,156
Ensembl chr 7:115,216,066...115,240,085 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2-naphthol binds to and results in decreased activity of THRB protein CTD PMID:18584933 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of 2-naphthol CTD PMID:8302279 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of 2-naphthol CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589 		JBrowse link
3-methoxycatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3-methoxycatechol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO 3-methoxycatechol results in increased expression of NFE2L2 mRNA CTD PMID:26862668 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
Aspidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO aspidin BB results in increased expression of BAX protein CTD PMID:23628508 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO aspidin BB results in decreased expression of BCL2 protein CTD PMID:23628508 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression		 ISO aspidin BB results in increased activity of CASP3 protein
aspidin BB results in increased expression of CASP3 protein modified form		 CTD PMID:23628508 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO aspidin BB results in increased expression of CCNA2 protein CTD PMID:23628508 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO aspidin BB results in increased expression of CCNE1 protein CTD PMID:23628508 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression ISO aspidin BB results in increased expression of CDK2 protein CTD PMID:23628508 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cycs cytochrome c, somatic affects localization ISO aspidin BB affects the localization of CYCS protein CTD PMID:23628508 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO aspidin BB results in increased expression of E2F1 protein CTD PMID:23628508 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO aspidin BB results in increased expression of PARP1 protein modified form CTD PMID:23628508 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression ISO aspidin BB results in increased expression of RB1 protein CTD PMID:23628508 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
carbaryl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity		 ISO
EXP		 [Carbaryl co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride promotes the reaction [Carbaryl results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Carbaryl results in decreased activity of ACHE protein]
[Carbaryl co-treated with Chlorpyrifos] results in decreased activity of ACHE protein		 CTD PMID:4859365 PMID:7713347 PMID:14644616 PMID:16256972 PMID:19934164 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase decreases activity EXP Carbaryl results in decreased activity of AGXT protein CTD PMID:2119399 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO
EXP		 AHR protein affects the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; Carbaryl binds to and results in increased activity of AHR protein; Carbaryl inhibits the reaction [beta-Naphthoflavone binds to and results in increased activity of AHR protein] CTD PMID:9169082 PMID:9853009 PMID:17553063 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alb albumin increases hydrolysis
multiple interactions		 EXP
ISO		 ALB protein results in increased hydrolysis of Carbaryl
bis(4-nitrophenyl)phosphate inhibits the reaction [ALB protein results in increased hydrolysis of Carbaryl]		 CTD PMID:27665777 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Ar androgen receptor affects binding EXP Carbaryl binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions		 EXP Carbaryl results in decreased activity of BCHE protein
[Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein		 CTD PMID:20708061 PMID:22649187 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2l11 Bcl2-like 11 decreases expression ISO Carbaryl results in decreased expression of BCL2L11 mRNA CTD PMID:27829164 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases secretion ISO Carbaryl results in decreased secretion of BDNF protein CTD PMID:35292247 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp3 caspase 3 increases expression EXP Carbaryl results in increased expression of CASP3 CTD PMID:27296064 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Carbaryl results in decreased expression of CEBPA mRNA CTD PMID:27829164 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Carbaryl results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; Carbaryl results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Carbaryl results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Carbaryl results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP Carbaryl results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; Carbaryl results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14644616 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Carbaryl results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]; Carbaryl results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions		 ISO
EXP		 Carbaryl results in increased activity of CYP1A1 protein
Carbaryl results in increased expression of CYP1A1 mRNA; Carbaryl results in increased expression of CYP1A1 protein
AHR protein affects the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; Methoxsalen inhibits the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]		 CTD PMID:9169082 PMID:9858662 PMID:11226373 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity		 ISO
EXP		 Carbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]; Carbaryl inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]
Carbaryl results in increased expression of CYP1A2 protein
Carbaryl results in decreased activity of CYP1A2 protein		 CTD PMID:9858662 PMID:16790556 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
increases expression		 ISO Carbaryl results in increased activity of CYP2B6 protein
Carbaryl results in increased expression of CYP2B6 mRNA		 CTD PMID:22310298 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity		 ISO Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
Carbaryl results in decreased activity of CYP2E1 protein		 CTD PMID:22634058 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Carbaryl results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Carbaryl results in increased expression of DDIT3 mRNA CTD PMID:11226373 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Carbaryl results in increased expression of DNAJB4 mRNA CTD PMID:27829164 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Carbaryl results in increased expression of DNAJB9 mRNA CTD PMID:27829164 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Carbaryl results in increased expression of DNAJC3 mRNA CTD PMID:27829164 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Carbaryl results in decreased expression of E2F5 mRNA CTD PMID:27829164 NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990 		JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO Carbaryl results in decreased expression of ENC1 mRNA CTD PMID:27829164 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Carbaryl binds to and results in decreased activity of ESR1 protein; Carbaryl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 PMID:16626760 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression		 ISO Carbaryl binds to and results in decreased activity of ESR2 protein
Carbaryl results in decreased expression of ESR2 mRNA		 CTD PMID:16626760 PMID:27829164 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression		 ISO Carbaryl results in increased expression of FOS mRNA
Carbaryl results in decreased expression of FOS mRNA		 CTD PMID:11226373 PMID:27829164 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO Carbaryl results in decreased expression of FOXO1 mRNA CTD PMID:27829164 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Carbaryl inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; Carbaryl inhibits the reaction [FSHB protein results in increased secretion of Progesterone] CTD PMID:16413094 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions		 EXP Carbaryl results in increased activity of G6PD protein
[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]		 CTD PMID:27214522 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO Carbaryl results in decreased expression of GADD45B mRNA CTD PMID:27829164 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Carbaryl results in increased expression of GCLM mRNA CTD PMID:27829164 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpx5 glutathione peroxidase 5 increases expression ISO Carbaryl results in increased expression of GPX5 mRNA CTD PMID:27829164 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression EXP Carbaryl results in increased expression of GRIN2B protein CTD PMID:28975519 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Carbaryl results in increased expression of HERPUD1 mRNA CTD PMID:27829164 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Carbaryl results in increased expression of HMOX1 mRNA CTD PMID:27829164 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Carbaryl results in increased expression of HSPA5 mRNA CTD PMID:11226373 PMID:27829164 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 decreases expression ISO Carbaryl results in decreased expression of HSPA6 mRNA CTD PMID:27829164 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:15907790 PMID:18177342 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Carbaryl analog results in decreased susceptibility to IL2 protein; Carbaryl results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity EXP Carbaryl results in decreased activity of KYAT1 protein CTD PMID:2119399 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO Carbaryl promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of MAP2 mRNA] CTD PMID:32949729 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Carbaryl results in decreased expression of MITF mRNA CTD PMID:27829164 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mtnr1a melatonin receptor 1A affects binding
multiple interactions		 ISO Carbaryl binds to MTNR1A protein
Carbaryl inhibits the reaction [Melatonin binds to MTNR1A protein]		 CTD PMID:28027439 NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919 		JBrowse link
G Mtnr1b melatonin receptor 1B affects binding
multiple interactions		 ISO Carbaryl binds to MTNR1B protein
Carbaryl inhibits the reaction [Melatonin binds to MTNR1B protein]; Guanosine Triphosphate inhibits the reaction [Carbaryl inhibits the reaction [Melatonin binds to MTNR1B protein]]		 CTD PMID:28027439 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737 		JBrowse link
G Nefh neurofilament heavy chain increases phosphorylation ISO Carbaryl results in increased phosphorylation of NEFH protein CTD PMID:16256972 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Carbaryl inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Carbaryl inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:15907790 PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Dithiothreitol inhibits the reaction [Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Mercaptoethanol inhibits the reaction [Carbaryl inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] CTD PMID:15907790 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
increases activity		 ISO
EXP		 Carbaryl results in increased expression of NR1I2 mRNA
Carbaryl results in increased activity of NR1I2 protein		 CTD PMID:22310298 PMID:27665777 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity EXP Carbaryl results in increased activity of NR1I3 protein CTD PMID:27665777 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions ISO Carbaryl inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of OTX2 mRNA] CTD PMID:32949729 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Pax6 paired box 6 multiple interactions ISO Carbaryl inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of PAX6 mRNA] CTD PMID:32949729 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdxk pyridoxal kinase decreases activity ISO Carbaryl results in decreased activity of PDXK protein CTD PMID:2547861 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Carbaryl inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity EXP Carbaryl results in decreased activity of PNPLA6 protein CTD PMID:7713347 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO Carbaryl promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of POU5F1 mRNA] CTD PMID:32949729 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity EXP Carbaryl results in increased activity of PPARA protein CTD PMID:27665777 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Carbaryl inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:15907790 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression		 ISO Carbaryl inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]
Carbaryl results in decreased expression of STAR mRNA		 CTD PMID:16413094 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity ISO
EXP		 Carbaryl results in decreased activity of TDO2 protein CTD PMID:2119399 PMID:2547861 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO Carbaryl results in increased expression of TGFB2 mRNA CTD PMID:27829164 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions
affects binding		 ISO Carbaryl binds to and results in decreased activity of THRB protein
Carbaryl binds to THRB protein		 CTD PMID:18584933 PMID:28973306 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tpo thyroid peroxidase increases activity ISO Carbaryl results in increased activity of TPO protein CTD PMID:21809831 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Wnt6 Wnt family member 6 decreases expression ISO Carbaryl results in decreased expression of WNT6 mRNA CTD PMID:27829164 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Carbaryl results in increased expression of XBP1 mRNA CTD PMID:27829164 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
dieckol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO dieckol results in decreased expression of and results in decreased phosphorylation of AKT1 protein
dieckol results in decreased phosphorylation of AKT1 protein		 CTD PMID:31291034 PMID:36683349 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]
dieckol results in increased expression of BAX protein		 CTD PMID:33051972 PMID:33347706 PMID:36683349 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
dieckol results in decreased expression of BCL2 protein		 CTD PMID:33051972 PMID:33347706 PMID:36683349 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO dieckol results in increased activity of CASP3 protein
dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]		 CTD PMID:31291034 PMID:33347706 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO dieckol results in increased activity of CASP8 protein CTD PMID:31291034 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
increases expression
multiple interactions		 ISO dieckol results in increased activity of CASP9 protein
dieckol results in increased expression of CASP9 protein
dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]		 CTD PMID:31291034 PMID:33347706 PMID:36683349 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]
dieckol results in decreased activity of CAT protein		 CTD PMID:33051972 PMID:33347706 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO dieckol results in decreased expression of CCND1 protein CTD PMID:33051972 PMID:36683349 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO dieckol results in increased expression of CDH1 protein CTD PMID:31291034 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 decreases expression ISO dieckol results in decreased expression of CDH2 protein CTD PMID:31291034 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO dieckol results in decreased expression of CDK4 protein CTD PMID:36683349 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO dieckol results in decreased expression of CDK6 protein CTD PMID:36683349 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased phosphorylation of FOS protein] CTD PMID:33164846 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein] CTD PMID:33347706 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL18 mRNA] CTD PMID:33347706 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL1B mRNA]; dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL1B protein]
dieckol inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]
dieckol results in decreased expression of IL1B protein		 CTD PMID:33051972 PMID:33164846 PMID:33347706 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL6 mRNA]; dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL6 protein]
dieckol inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]		 CTD PMID:33164846 PMID:33347706 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased phosphorylation of JUN protein] CTD PMID:33164846 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein] CTD PMID:33164846 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein] CTD PMID:33164846 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression
multiple interactions		 ISO dieckol results in decreased expression of MMP1 mRNA; dieckol results in decreased expression of MMP1 protein
dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP1 protein]		 CTD PMID:19330880 PMID:33164846 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression
multiple interactions		 ISO dieckol results in decreased expression of MMP13 mRNA; dieckol results in decreased expression of MMP13 protein
dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP13 protein]		 CTD PMID:19330880 PMID:33164846 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP2 protein] CTD PMID:33164846 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO dieckol results in decreased expression of MMP3 mRNA; dieckol results in decreased expression of MMP3 protein CTD PMID:19330880 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp8 matrix metallopeptidase 8 multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP8 protein] CTD PMID:33164846 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO dieckol results in decreased expression of MMP9 protein
dieckol inhibits the reaction [Particulate Matter results in increased expression of MMP9 protein]		 CTD PMID:31291034 PMID:33164846 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO dieckol results in decreased phosphorylation of MTOR protein CTD PMID:31291034 PMID:36683349 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased expression of NFKB1 protein] CTD PMID:33164846 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO dieckol affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NFKBIA protein]; dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of NFKBIA protein] CTD PMID:33347706 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO dieckol results in decreased expression of NOS2 mRNA; dieckol results in decreased expression of NOS2 protein CTD PMID:19330880 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO dieckol results in decreased expression of PCNA protein CTD PMID:33051972 PMID:36683349 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO dieckol results in decreased expression of PLAU protein CTD PMID:31291034 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO dieckol results in decreased expression of PTGS2 mRNA; dieckol results in decreased expression of PTGS2 protein
dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PTGS2 mRNA]		 CTD PMID:19330880 PMID:33347706 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO dieckol inhibits the reaction [Particulate Matter results in increased expression of RELA protein] CTD PMID:33164846 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression ISO dieckol results in decreased expression of RPS6KB1 protein CTD PMID:31291034 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TGFB1 mRNA] CTD PMID:33347706 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF mRNA]; dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TNF protein]
dieckol inhibits the reaction [Particulate Matter results in increased expression of TNF protein]
dieckol results in decreased expression of TNF protein		 CTD PMID:33051972 PMID:33164846 PMID:33347706 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA] CTD PMID:33347706 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression ISO dieckol results in decreased expression of TWIST1 protein CTD PMID:31291034 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Vim vimentin decreases expression ISO dieckol results in decreased expression of VIM protein CTD PMID:31291034 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
eckol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO eckol results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:21514314 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [eckol co-treated with temozolomide] results in increased cleavage of CASP8 protein CTD PMID:21514314 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO eckol results in decreased expression of CTNNB1 protein CTD PMID:21514314 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression ISO eckol results in decreased expression of CYBB protein CTD PMID:21514314 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
multiple interactions		 ISO eckol results in increased phosphorylation of FOXO3 protein
FOXO3 mutant form inhibits the reaction [eckol results in increased expression of SOD2 protein]		 CTD PMID:24700636 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO eckol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:21514314 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO eckol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein CTD PMID:21514314 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Msi1 musashi RNA-binding protein 1 decreases expression ISO eckol results in decreased expression of MSI1 protein CTD PMID:21514314 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076 		JBrowse link
G Nes nestin decreases expression ISO eckol results in decreased expression of NES protein CTD PMID:21514314 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Prom1 prominin 1 decreases expression ISO eckol results in decreased expression of PROM1 protein CTD PMID:21514314 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases activity ISO eckol results in decreased activity of RAF1 protein CTD PMID:21514314 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO eckol inhibits the reaction [Hydrogen Peroxide results in decreased expression of and results in decreased activity of SOD2 protein]; FOXO3 mutant form inhibits the reaction [eckol results in increased expression of SOD2 protein]
eckol results in increased expression of SOD2 mRNA; eckol results in increased expression of SOD2 protein		 CTD PMID:24700636 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO eckol results in decreased expression of SOX2 protein CTD PMID:21514314 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
orcinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO orcinol results in decreased activity of CYP1A1 protein CTD PMID:24667653 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
phloroglucinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Phloroglucinol analog results in decreased phosphorylation of AKT1 protein CTD PMID:23178381 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Phloroglucinol metabolite results in increased expression of BAX protein CTD PMID:22796323 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Phloroglucinol metabolite results in decreased expression of BCL2 protein CTD PMID:22796323 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO Phloroglucinol analog results in increased cleavage of CASP3 protein; Phloroglucinol metabolite results in increased cleavage of CASP3 protein CTD PMID:22796323 PMID:23178381 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO Phloroglucinol metabolite results in increased cleavage of CASP9 protein CTD PMID:22796323 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:26054450 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Phloroglucinol results in increased expression of GCLC protein CTD PMID:20188716 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Phloroglucinol analog results in increased expression of GDF15 protein CTD PMID:23178381 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO Phloroglucinol analog results in decreased phosphorylation of GSK3B protein CTD PMID:23178381 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Phloroglucinol analog results in increased cleavage of PARP1 protein; Phloroglucinol metabolite results in increased cleavage of PARP1 protein CTD PMID:22796323 PMID:23178381 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein] CTD PMID:26054450 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:26054450 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein]; Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:26054450 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
propranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP Propranolol inhibits the reaction [Parathion results in increased expression of AANAT protein] CTD PMID:10685507 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions		 ISO Propranolol results in increased expression of ABCB1 mRNA
Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]		 CTD PMID:15276086 PMID:16671962 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ada adenosine deaminase multiple interactions EXP Propranolol promotes the reaction [ADA protein results in decreased susceptibility to Norepinephrine] CTD PMID:7949234 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adm adrenomedullin decreases response to substance EXP Propranolol results in decreased susceptibility to ADM protein CTD PMID:9845272 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects response to substance
affects binding
increases activity
increases expression		 EXP
ISO		 Propranolol binds to and results in decreased activity of ADRB1 protein; Propranolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Propranolol inhibits the reaction [Dihydroalprenolol binds to ADRB1 protein]
ADRB1 protein polymorphism affects the susceptibility to Propranolol
Propranolol binds to ADRB1 protein
[Propranolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; Propranolol binds to and results in decreased activity of ADRB1 protein; Propranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [CGP 12177 results in increased activity of ADRB1 protein]; Propranolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Propranolol inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRB1 protein]
Propranolol results in increased activity of ADRB1 protein
Propranolol results in increased expression of ADRB1 mRNA		 CTD PMID:2462161 PMID:6141285 PMID:9593075 PMID:10372227 PMID:10952688 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression
multiple interactions
affects binding
increases expression		 ISO
EXP		 Propranolol results in decreased expression of ADRB2 mRNA
Propranolol binds to and results in decreased activity of ADRB2 protein; Propranolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Propranolol inhibits the reaction [Dihydroalprenolol binds to ADRB2 protein]
Propranolol binds to ADRB2 protein
Propranolol results in increased expression of ADRB2 mRNA
[Propranolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS protein; [Propranolol co-treated with ADRB2 protein] results in increased expression of GRK2 protein; Propranolol binds to and results in decreased activity of ADRB2 protein; Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol results in increased phosphorylation of ADRB2 protein]; Propranolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Propranolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [Norepinephrine binds to ADRB2 protein]; Propranolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein]		 CTD PMID:2169833 PMID:2462161 PMID:2897299 PMID:6141285 PMID:9593075 More... NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
affects response to substance		 ISO Propranolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]
ADRB3 affects the susceptibility to Propranolol		 CTD PMID:11159692 PMID:14730417 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Agt angiotensinogen multiple interactions
decreases expression		 ISO Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Propranolol inhibits the reaction [REN protein results in increased cleavage of AGT protein]
Propranolol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Propranolol results in decreased expression of AGT protein		 CTD PMID:14627 PMID:1653766 PMID:7104148 PMID:7843740 PMID:12606818 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 ISO Propranolol results in decreased phosphorylation of AKT1 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased phosphorylation of AKT1 protein]		 CTD PMID:30130526 PMID:31838054 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein]]; Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] CTD PMID:18218859 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Amy2a3 amylase 2a3 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:201,317,916...201,326,487
Ensembl chr 2:201,317,920...201,326,532 		JBrowse link
G Angpt2 angiopoietin 2 decreases expression
multiple interactions		 ISO Propranolol results in decreased expression of ANGPT2 mRNA; Propranolol results in decreased expression of ANGPT2 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of BCL2 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of MKI67 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in decreased phosphorylation of AKT1 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in increased expression of BAX protein]		 CTD PMID:31838054 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Arf6 ADP-ribosylation factor 6 affects localization ISO Propranolol affects the localization of ARF6 protein CTD PMID:16280360 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]] CTD PMID:17925438 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP Propranolol inhibits the reaction [Terbutaline results in increased expression of ATP1A1 mRNA] CTD PMID:9700104 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
increases expression		 EXP
ISO		 Propranolol results in decreased expression of BAX mRNA
Propranolol inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]
Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased expression of BAX protein]
ANGPT2 protein inhibits the reaction [Propranolol results in increased expression of BAX protein]		 CTD PMID:11218852 PMID:31838054 PMID:35738838 PMID:36707890 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases expression		 EXP
ISO		 Propranolol results in increased expression of BCL2 mRNA
Propranolol inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
Propranolol results in decreased expression of BCL2 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of BCL2 protein]		 CTD PMID:11218852 PMID:31838054 PMID:36707890 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
affects activity		 EXP Propranolol promotes the reaction [CALCA protein affects the susceptibility to Norepinephrine]
Propranolol affects the activity of CALCA protein		 CTD PMID:7906887 PMID:8058111 PMID:10075105 PMID:18055875 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
decreases expression		 ISO
EXP		 Propranolol results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]; Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]
Propranolol results in increased activity of CASP3 protein
Palmitic Acid promotes the reaction [Propranolol results in increased activity of CASP3 protein]
Propranolol results in decreased expression of CASP3 mRNA		 CTD PMID:11218852 PMID:19106745 PMID:22700542 PMID:35738838 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO Propranolol results in increased activity of CASP7 protein CTD PMID:22700542 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions		 ISO
EXP		 Propranolol results in increased cleavage of CASP9 protein
Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased cleavage of CASP9 protein]		 CTD PMID:19106745 PMID:35738838 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Propranolol inhibits the reaction [Epinephrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]]
Propranolol inhibits the reaction [Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]]; Propranolol promotes the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]		 CTD PMID:9863660 PMID:12538206 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein] CTD PMID:21177286 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Propranolol inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein] CTD PMID:15522277 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Propranolol affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein]; Propranolol inhibits the reaction [acephate results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [acephate results in increased secretion of CRH protein]; Propranolol inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [methamidophos results in increased secretion of CRH protein] CTD PMID:3497798 PMID:12039681 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO
EXP		 Propranolol results in increased expression of CYP1A1 protein
Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]
Propranolol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]		 CTD PMID:15618653 PMID:15627480 PMID:15710352 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
multiple interactions		 ISO
EXP		 CYP1A2 protein affects the metabolism of Propranolol
Propranolol results in increased expression of CYP1A2 protein
Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]		 CTD PMID:15286053 PMID:15618653 PMID:15710352 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Propranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] CTD PMID:22167199 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases oxidation
affects metabolic processing		 ISO CYP2C19 protein results in increased oxidation of Propranolol
CYP2C19 protein affects the metabolism of Propranolol		 CTD PMID:15286053 PMID:19853591 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Propranolol inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
increases oxidation
affects metabolic processing		 ISO CYP2D6 protein results in increased metabolism of Propranolol
CYP2D6 protein results in increased oxidation of Propranolol
CYP2D6 protein affects the metabolism of Propranolol		 CTD PMID:12464242 PMID:15286053 PMID:19853591 PMID:21184751 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases oxidation ISO CYP3A4 protein results in increased oxidation of Propranolol CTD PMID:19853591 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 decreases expression
multiple interactions		 ISO Propranolol results in decreased expression of DLL4 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP2 protein]; DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP9 protein]		 CTD PMID:30130526 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]] CTD PMID:18787115 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein] CTD PMID:15621046 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein] CTD PMID:11880281 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Propranolol results in decreased expression of FAS mRNA CTD PMID:11218852 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP Propranolol results in increased expression of FGF1 mRNA CTD PMID:15264218 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Propranolol CTD PMID:26062974 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Norepinephrine co-treated with Propranolol] results in increased expression of FN1 protein CTD PMID:11821714 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP Propranolol inhibits the reaction [3-(N-phenylamino)-1,2-propanediol 1,2-dioleoyl ester analog results in increased expression of FOS mRNA]; Propranolol inhibits the reaction [Ethanol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS]
Propranolol results in increased expression of FOS protein		 CTD PMID:7905536 PMID:9748542 PMID:15501433 PMID:22236039 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]]; Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gja1 gap junction protein, alpha 1 affects localization EXP Propranolol affects the localization of GJA1 protein CTD PMID:17445419 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gk glycerol kinase decreases activity EXP Propranolol results in decreased activity of GK protein CTD PMID:12736183 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gnas GNAS complex locus increases expression
multiple interactions		 EXP
ISO		 Propranolol results in increased expression of GNAS mRNA
[Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS protein		 CTD PMID:10455254 PMID:20668454 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions
increases expression
decreases expression		 ISO [Propranolol co-treated with ADRB2 protein] results in increased expression of GRK2 protein
Propranolol results in increased expression of GRK2 protein
Propranolol results in decreased expression of GRK2 protein		 CTD PMID:9788834 PMID:10455254 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation EXP Propranolol results in decreased phosphorylation of GSK3B protein CTD PMID:22982863 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA] CTD PMID:19483313 PMID:24929186 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpca hippocalcin affects localization EXP Propranolol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP Propranolol binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Il10 interleukin 10 increases expression EXP Propranolol results in increased expression of IL10 mRNA CTD PMID:16908771 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion		 ISO
EXP		 Propranolol promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Propranolol results in decreased secretion of IL1B protein		 CTD PMID:11854442 PMID:16386803 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Propranolol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of IL6 protein] CTD PMID:12619890 PMID:29247675 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression		 ISO Propranolol inhibits the reaction [Epinephrine results in decreased expression of INS protein]
Propranolol results in decreased expression of INS protein		 CTD PMID:3019152 PMID:6018752 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 multiple interactions ISO Propranolol results in decreased activity of [KCNH2 protein binds to KCNE2 protein] CTD PMID:15679475 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Propranolol results in decreased activity of [KCNH2 protein binds to KCNE2 protein]; Propranolol results in decreased activity of [KCNH2 protein binds to KCNH2 protein]
Propranolol results in decreased activity of KCNH2 protein		 CTD PMID:15679475 PMID:16314852 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 affects response to substance ISO KCNJ2 gene affects the susceptibility to Propranolol CTD PMID:15028050 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO Propranolol results in increased expression of KCNJ3 mRNA CTD PMID:15603589 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 affects response to substance ISO KCNQ1 gene affects the susceptibility to Propranolol CTD PMID:15028050 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Lep leptin multiple interactions
increases expression		 ISO
EXP		 Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]
Propranolol results in increased expression of LEP protein		 CTD PMID:11022189 PMID:24250662 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor increases expression EXP Propranolol results in increased expression of LEPR mRNA CTD PMID:24250662 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Propranolol inhibits the reaction [Norepinephrine results in increased expression of LPL mRNA] CTD PMID:9032464 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP		 [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; Propranolol inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]		 CTD PMID:11093795 PMID:11880281 PMID:17925438 PMID:18448488 PMID:19903766 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP		 [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; Propranolol inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]		 CTD PMID:11093795 PMID:11880281 PMID:17925438 PMID:18448488 PMID:19903766 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MCL1 protein] CTD PMID:19903766 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mir34a microRNA 34a multiple interactions ISO Propranolol inhibits the reaction [Arsenic Trioxide results in increased expression of MIR34A mRNA] CTD PMID:36707890 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
multiple interactions		 ISO Propranolol results in decreased expression of MKI67 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of MKI67 protein]		 CTD PMID:31838054 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
decreases secretion		 ISO Propranolol results in decreased expression of MMP2; Propranolol results in decreased expression of MMP2 mRNA; Propranolol results in decreased expression of MMP2 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP2 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]
Propranolol results in decreased secretion of MMP2 protein		 CTD PMID:20424515 PMID:21042766 PMID:24929186 PMID:30130526 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
decreases secretion		 ISO Propranolol results in decreased expression of MMP9; Propranolol results in decreased expression of MMP9 mRNA; Propranolol results in decreased expression of MMP9 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP9 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; Propranolol inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]
Propranolol results in decreased secretion of MMP9 protein		 CTD PMID:16574429 PMID:20424515 PMID:21042766 PMID:24929186 PMID:30130526 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression		 EXP Propranolol promotes the reaction [Norepinephrine results in increased expression of MYH7 mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]
Propranolol results in increased expression of MYH7 mRNA		 CTD PMID:17592507 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Propranolol affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA] CTD PMID:2174743 PMID:2853697 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Propranolol affects the expression of NOS3 CTD PMID:10889169 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Propranolol results in decreased expression of NOTCH1 protein CTD PMID:30130526 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nppa natriuretic peptide A multiple interactions
affects activity
increases expression		 EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Norepinephrine results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Propranolol affects the activity of NPPA protein modified form
Propranolol results in increased expression of NPPA mRNA		 CTD PMID:1363893 PMID:10997724 PMID:17592507 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B affects activity EXP Propranolol affects the activity of NPPB protein modified form CTD PMID:1363893 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Propranolol results in increased activity of NR1I2 protein CTD PMID:28259787 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity
multiple interactions		 ISO Propranolol results in increased activity of ODC1 protein
Propranolol inhibits the reaction [Clenbuterol results in increased activity of ODC1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ODC1 protein]		 CTD PMID:2286747 PMID:6284819 PMID:10353628 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Orm1 orosomucoid 1 affects binding EXP propranolol affects binding to Orm1 protein in rat serum RGD PMID:3252025 RGD:2316648 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Penk proenkephalin multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA] CTD PMID:1363325 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pln phospholamban multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein] CTD PMID:10997724 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pomc proopiomelanocortin increases secretion EXP Propranolol results in increased secretion of POMC protein CTD PMID:22236039 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression		 ISO [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]; Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA]
Propranolol results in decreased expression of PPARGC1A mRNA		 CTD PMID:16513826 PMID:17446185 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkca protein kinase C, alpha decreases expression EXP Propranolol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta decreases expression EXP Propranolol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO Propranolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; Propranolol inhibits the reaction [Nicotine results in increased activity of PTGS2 protein]; Propranolol promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; Propranolol promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Propranolol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Propranolol results in decreased expression of PTGS2; Propranolol results in decreased expression of PTGS2 mRNA; Propranolol results in decreased expression of PTGS2 protein		 CTD PMID:11854442 PMID:12872987 PMID:15210717 PMID:18805435 PMID:20424515 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Ren renin multiple interactions
decreases activity
decreases expression		 ISO
EXP		 Propranolol affects the reaction [Anesthetics, Combined results in increased activity of REN protein]; Propranolol affects the reaction [Nitroprusside promotes the reaction [Anesthetics, Combined results in increased activity of REN protein]]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of REN protein]; Propranolol inhibits the reaction [Nitroprusside results in increased activity of REN protein]; Propranolol inhibits the reaction [REN protein results in increased cleavage of AGT protein]
Propranolol results in decreased activity of REN protein
Propranolol inhibits the reaction [ioxitalamic acid results in increased expression of REN protein]; Propranolol inhibits the reaction [Prazosin results in increased transport of REN protein]; Propranolol inhibits the reaction [Yohimbine results in increased expression of REN protein]
Propranolol results in decreased expression of REN protein		 CTD PMID:145319 PMID:200433 PMID:637424 PMID:653302 PMID:791319 More... NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
multiple interactions		 ISO Propranolol results in increased phosphorylation of RPS6KB1 protein
Sirolimus inhibits the reaction [Propranolol results in increased phosphorylation of RPS6KB1 protein]		 CTD PMID:16537399 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions EXP Propranolol inhibits the reaction [Terbutaline results in increased expression of SCNN1A mRNA] CTD PMID:9700104 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Serpinf1 serpin family F member 1 increases expression ISO propranolol increases expression of Serpinf1 protein in mononuclear phagocytes RGD PMID:31682714 RGD:27226692 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Propranolol inhibits the reaction [Arsenic Trioxide results in decreased expression of SIRT1 mRNA]; Propranolol inhibits the reaction [Arsenic Trioxide results in decreased expression of SIRT1 protein] CTD PMID:36707890 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Propranolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Propranolol inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Propranolol inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Propranolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:21641380 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Propranolol inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Propranolol inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions ISO Propranolol inhibits the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein] CTD PMID:15621046 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 PMID:20106947 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO Propranolol inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO Propranolol results in decreased expression of TEK mRNA; Propranolol results in decreased expression of TEK protein CTD PMID:31838054 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO Propranolol inhibits the reaction [Epinephrine results in decreased expression of THY1]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of THY1]; Propranolol inhibits the reaction [Norepinephrine results in decreased expression of THY1] CTD PMID:7558147 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP Propranolol inhibits the reaction [Dopamine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; Propranolol inhibits the reaction [Ozone results in increased expression of TNF mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of TNF protein]; Propranolol promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Propranolol results in increased expression of TNF protein		 CTD PMID:11752888 PMID:15081246 PMID:29247675 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B increases glucuronidation EXP UGT2B protein results in increased glucuronidation of Propranolol CTD PMID:15801678 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions		 ISO Propranolol results in decreased expression of VEGFA mRNA; Propranolol results in decreased expression of VEGFA protein
Propranolol inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA]		 CTD PMID:10788502 PMID:20424515 PMID:30130526 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
propranolol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 decreases binding EXP propranolol hydrochloride decreases binding to the beta2-adrenergic receptor RGD PMID:12875885 RGD:1598755 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
pyrogallol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of A2M mRNA] CTD PMID:20362636 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO Pyrogallol results in decreased expression of ADARB1 mRNA CTD PMID:20362636 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Add1 adducin 1 increases expression ISO Pyrogallol results in increased expression of ADD1 mRNA CTD PMID:20362636 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Ak4 adenylate kinase 4 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of AK4 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of AK4 mRNA]		 CTD PMID:20362636 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO Pyrogallol results in increased expression of AKR1A1 mRNA CTD PMID:20362636 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of ALDH1A1 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of ALDH1A1 mRNA]		 CTD PMID:20362636 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Pyrogallol results in increased expression of ALPL mRNA CTD PMID:20362636 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 increases expression ISO Pyrogallol results in increased expression of AMPD2 mRNA CTD PMID:20362636 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271 		JBrowse link
G Anapc1 anaphase promoting complex subunit 1 increases expression ISO Pyrogallol results in increased expression of ANAPC1 mRNA CTD PMID:20362636 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273 		JBrowse link
G Ankrd6 ankyrin repeat domain 6 increases expression ISO Pyrogallol results in increased expression of ANKRD6 mRNA CTD PMID:20362636 NCBI chr 5:47,197,981...47,343,183
Ensembl chr 5:47,202,873...47,343,090 		JBrowse link
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 increases expression ISO Pyrogallol results in increased expression of AP1G1 mRNA CTD PMID:20362636 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Pyrogallol results in increased expression of APOA1 mRNA CTD PMID:20362636 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallol; Hydrogen Peroxide promotes the reaction [[Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallol] CTD PMID:15699049 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arf1 ADP-ribosylation factor 1 increases expression ISO Pyrogallol results in increased expression of ARF1 mRNA CTD PMID:20362636 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Pyrogallol results in increased expression of ARHGDIA mRNA CTD PMID:20362636 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of ASNS mRNA] CTD PMID:20362636 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression ISO Pyrogallol results in increased expression of ATP1B1 mRNA CTD PMID:20362636 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Bag4 BAG cochaperone 4 decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of BAG4 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of BAG4 mRNA]		 CTD PMID:20362636 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger increases expression ISO Pyrogallol results in increased expression of BMI1 mRNA CTD PMID:20362636 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression ISO Pyrogallol results in increased expression of BMPR1A mRNA CTD PMID:20362636 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Btg4 BTG anti-proliferation factor 4 increases expression ISO Pyrogallol results in increased expression of BTG4 mRNA CTD PMID:20362636 NCBI chr 8:51,410,774...51,425,802
Ensembl chr 8:51,422,061...51,425,796 		JBrowse link
G C1s complement C1s increases expression ISO Pyrogallol results in increased expression of C1S mRNA CTD PMID:20362636 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G Calml4 calmodulin-like 4 increases expression ISO Pyrogallol results in increased expression of CALML4 mRNA CTD PMID:20362636 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234 		JBrowse link
G Car8 carbonic anhydrase 8 increases expression ISO Pyrogallol results in increased expression of CAR8 mRNA CTD PMID:20362636 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Pyrogallol results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Pyrogallol results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Pyrogallol results in increased activity of CASP3 protein] CTD PMID:19000662 PMID:20191265 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO Pyrogallol results in increased activity of CASP8 protein CTD PMID:19000662 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression ISO Pyrogallol results in increased expression of CASP9 mRNA CTD PMID:20362636 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
increases activity
decreases expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Pyrogallol results in decreased expression of CAT protein]; pyrazolanthrone promotes the reaction [Pyrogallol results in decreased expression of CAT protein]; SB 203580 promotes the reaction [Pyrogallol results in decreased expression of CAT protein]
Pyrogallol results in increased activity of CAT protein
acetovanillone inhibits the reaction [Pyrogallol results in increased activity of CAT protein]		 CTD PMID:20191265 PMID:35944648 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Pyrogallol results in increased expression of CCND2 mRNA CTD PMID:20362636 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression ISO Pyrogallol results in increased expression of CCT3 mRNA CTD PMID:20362636 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cdh11 cadherin 11 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of CDH11 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of CDH11 mRNA]		 CTD PMID:20362636 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of CDK4 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of CDK4 mRNA]		 CTD PMID:20362636 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of CDKN1C mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of CDKN1C mRNA]		 CTD PMID:20362636 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cltc clathrin heavy chain increases expression ISO Pyrogallol results in increased expression of CLTC mRNA CTD PMID:20362636 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Pyrogallol results in increased expression of COL1A1 mRNA CTD PMID:20362636 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Pyrogallol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO Pyrogallol results in increased expression of COX4I1 mRNA CTD PMID:20362636 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 decreases expression ISO Pyrogallol results in decreased expression of COX6B1 mRNA CTD PMID:20362636 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001 		JBrowse link
G Cox7c cytochrome c oxidase subunit 7C increases expression ISO Pyrogallol results in increased expression of COX7C mRNA CTD PMID:20362636 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760 		JBrowse link
G Csnk2b casein kinase 2 beta increases expression ISO Pyrogallol results in increased expression of CSNK2B mRNA CTD PMID:20362636 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO Pyrogallol results in decreased expression of CTNNAL1 mRNA CTD PMID:20362636 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Cul3 cullin 3 increases expression ISO Pyrogallol results in increased expression of CUL3 mRNA CTD PMID:20362636 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression		 ISO Pyrogallol affects the localization of CYCS protein
Pyrogallol results in increased expression of CYCS mRNA		 CTD PMID:19000662 PMID:20362636 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
increases activity		 ISO Pyrogallol results in increased expression of CYP1A2 mRNA
resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP1A2 protein]; resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP1A2 mRNA]		 CTD PMID:18789925 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
multiple interactions
increases expression		 ISO Pyrogallol results in increased activity of CYP2E1 protein
resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein]; resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA]		 CTD PMID:18789925 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dcbld2 discoidin, CUB and LCCL domain containing 2 decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of DCBLD2 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of DCBLD2 mRNA]		 CTD PMID:20362636 NCBI chr11:42,125,525...42,179,927
Ensembl chr11:42,125,787...42,179,697 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of DDX3X mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of DDX3X mRNA]		 CTD PMID:20362636 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Pyrogallol results in increased expression of DLGAP5 mRNA CTD PMID:20362636 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dnal4 dynein, axonemal, light chain 4 increases expression ISO Pyrogallol results in increased expression of DNAL4 mRNA CTD PMID:20362636 NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283 		JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal increases expression ISO Pyrogallol results in increased expression of DNASE2A mRNA CTD PMID:20362636 NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO Pyrogallol results in increased expression of EEF1B2 mRNA CTD PMID:20362636 NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of EEF2 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of EEF2 mRNA]		 CTD PMID:20362636 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of EIF1A mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of EIF1A mRNA]		 CTD PMID:20362636 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of EIF4E2 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of EIF4E2 mRNA]		 CTD PMID:20362636 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 decreases expression ISO Pyrogallol results in decreased expression of EIF4ENIF1 mRNA CTD PMID:20362636 NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 increases expression ISO Pyrogallol results in increased expression of EIF4G1 mRNA CTD PMID:20362636 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941 		JBrowse link
G Eno1 enolase 1 increases expression ISO Pyrogallol results in increased expression of ENO1 mRNA CTD PMID:20362636 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Epo erythropoietin decreases expression EXP Pyrogallol results in decreased expression of EPO protein CTD PMID:9927288 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) increases expression ISO Pyrogallol results in increased expression of ERMAP mRNA CTD PMID:20362636 NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847 		JBrowse link
G Esd esterase D increases expression ISO Pyrogallol results in increased expression of ESD mRNA CTD PMID:20362636 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Fah fumarylacetoacetate hydrolase decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of FAH mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of FAH mRNA]		 CTD PMID:20362636 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO Pyrogallol results in increased expression of FKBP4 mRNA CTD PMID:20362636 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression ISO Pyrogallol results in increased expression of GART mRNA CTD PMID:20362636 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gata4 GATA binding protein 4 decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of GATA4 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of GATA4 mRNA]		 CTD PMID:20362636 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gnb1 G protein subunit beta 1 increases expression ISO Pyrogallol results in increased expression of GNB1 mRNA CTD PMID:20362636 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity
multiple interactions		 EXP Pyrogallol results in decreased activity of GPX1 protein
acetovanillone inhibits the reaction [Pyrogallol results in increased activity of GPX1 protein]		 CTD PMID:35944648 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions		 ISO Pyrogallol results in decreased activity of GSR protein
resveratrol inhibits the reaction [Pyrogallol results in decreased activity of GSR protein]		 CTD PMID:18789925 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 decreases expression ISO Pyrogallol results in decreased expression of HARS1 mRNA CTD PMID:20362636 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases expression ISO Pyrogallol results in increased expression of HBA1 mRNA CTD PMID:20362636 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hdgfl2 HDGF like 2 increases expression ISO Pyrogallol results in increased expression of HDGFL2 mRNA CTD PMID:20362636 NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 increases expression ISO Pyrogallol results in increased expression of HINT1 mRNA CTD PMID:20362636 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like increases expression ISO Pyrogallol results in increased expression of HNRNPDL mRNA CTD PMID:20362636 NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Pyrogallol results in increased expression of HPRT1 mRNA CTD PMID:20362636 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Pyrogallol results in increased expression of HSP90AA1 mRNA CTD PMID:20362636 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of HSPA8 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of HSPA8 mRNA]		 CTD PMID:20362636 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Pyrogallol results in increased expression of IL6 protein] CTD PMID:35944648 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO Pyrogallol results in increased expression of IQGAP1 mRNA CTD PMID:20362636 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO Pyrogallol results in increased expression of ISG20 mRNA CTD PMID:20362636 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Itfg1 integrin alpha FG-GAP repeat containing 1 increases expression ISO Pyrogallol results in increased expression of ITFG1 mRNA CTD PMID:20362636 NCBI chr19:21,210,697...21,331,285
Ensembl chr19:21,210,733...21,331,279 		JBrowse link
G Itm2b integral membrane protein 2B increases expression ISO Pyrogallol results in increased expression of ITM2B mRNA CTD PMID:20362636 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917 		JBrowse link
G Kcmf1 potassium channel modulatory factor 1 increases expression ISO Pyrogallol results in increased expression of KCMF1 mRNA CTD PMID:20362636 NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234 		JBrowse link
G Kif5b kinesin family member 5B multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of KIF5B mRNA] CTD PMID:20362636 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508 		JBrowse link
G Kifap3 kinesin-associated protein 3 increases expression ISO Pyrogallol results in increased expression of KIFAP3 mRNA CTD PMID:20362636 NCBI chr13:76,127,702...76,264,654
Ensembl chr13:76,127,696...76,264,650 		JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO Pyrogallol results in increased expression of KLF4 mRNA CTD PMID:20362636 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Krt18 keratin 18 increases expression ISO Pyrogallol results in increased expression of KRT18 mRNA CTD PMID:20362636 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 increases expression ISO Pyrogallol results in increased expression of LAMP2 mRNA CTD PMID:20362636 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Lpo lactoperoxidase multiple interactions EXP acetovanillone inhibits the reaction [Pyrogallol results in increased activity of LPO protein] CTD PMID:35944648 NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535 		JBrowse link
G Map4 microtubule-associated protein 4 increases expression ISO Pyrogallol results in increased expression of MAP4 mRNA CTD PMID:20362636 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 increases expression ISO Pyrogallol results in increased expression of MAPK13 mRNA CTD PMID:20362636 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 increases expression ISO Pyrogallol results in increased expression of MBTPS1 mRNA CTD PMID:20362636 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Mif macrophage migration inhibitory factor decreases expression ISO Pyrogallol results in decreased expression of MIF mRNA CTD PMID:20362636 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Pyrogallol results in increased expression of MMP23 mRNA CTD PMID:20362636 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433 		JBrowse link
G Mrps25 mitochondrial ribosomal protein S25 increases expression ISO Pyrogallol results in increased expression of MRPS25 mRNA CTD PMID:20362636 NCBI chr 4:124,668,320...124,680,086
Ensembl chr 4:124,668,094...124,680,057 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO Pyrogallol results in increased expression of MSRB1 mRNA CTD PMID:20362636 NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression ISO Pyrogallol results in increased expression of NAP1L1 mRNA CTD PMID:20362636 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593 		JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 increases expression ISO Pyrogallol results in increased expression of NDUFB10 mRNA CTD PMID:20362636 NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO Pyrogallol results in decreased expression of NFE2L2 mRNA CTD PMID:31967339 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nrk Nik related kinase decreases expression ISO Pyrogallol results in decreased expression of NRK mRNA CTD PMID:20362636 NCBI chr  X:102,365,765...102,462,957
Ensembl chr  X:102,365,765...102,459,657 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 increases expression ISO Pyrogallol results in increased expression of NUBP1 mRNA CTD PMID:20362636 NCBI chr10:5,259,328...5,270,848 JBrowse link
G Nup58 nucleoporin 58 increases expression ISO Pyrogallol results in increased expression of NUP58 mRNA CTD PMID:20362636 NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO Pyrogallol results in increased expression of PCNA mRNA CTD PMID:20362636 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdcd10 programmed cell death 10 increases expression ISO Pyrogallol results in increased expression of PDCD10 mRNA CTD PMID:20362636 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO Pyrogallol results in increased expression of PDIA3 mRNA CTD PMID:20362636 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of PELI1 mRNA] CTD PMID:20362636 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pex14 peroxisomal biogenesis factor 14 decreases expression ISO Pyrogallol results in decreased expression of PEX14 mRNA CTD PMID:20362636 NCBI chr 5:159,399,776...159,536,260
Ensembl chr 5:159,399,776...159,536,272 		JBrowse link
G Pfdn1 prefoldin subunit 1 increases expression ISO Pyrogallol results in increased expression of PFDN1 mRNA CTD PMID:20362636 NCBI chr18:28,014,145...28,067,148
Ensembl chr18:28,014,145...28,067,064 		JBrowse link
G Phb1 prohibitin 1 increases expression ISO Pyrogallol results in increased expression of PHB1 mRNA CTD PMID:20362636 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of PHGDH mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of PHGDH mRNA]		 CTD PMID:20362636 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 decreases expression ISO Pyrogallol results in decreased expression of PHKA2 mRNA CTD PMID:20362636 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466 		JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO Pyrogallol results in increased expression of PIDD1 mRNA CTD PMID:20362636 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of PKIG mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of PKIG mRNA]		 CTD PMID:20362636 NCBI chr 3:152,330,477...152,398,085
Ensembl chr 3:152,366,041...152,398,082 		JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO Pyrogallol results in increased expression of PLP2 mRNA CTD PMID:20362636 NCBI chr  X:14,834,249...14,837,648
Ensembl chr  X:14,834,231...14,838,514 		JBrowse link
G Plxdc2 plexin domain containing 2 increases expression ISO Pyrogallol results in increased expression of PLXDC2 mRNA CTD PMID:20362636 NCBI chr17:79,169,238...79,594,279
Ensembl chr17:79,196,369...79,585,282 		JBrowse link
G Polr1f RNA polymerase I subunit F increases expression ISO Pyrogallol results in increased expression of POLR1F mRNA CTD PMID:20362636 NCBI chr 6:50,053,289...50,070,514
Ensembl chr 6:50,053,289...50,070,514 		JBrowse link
G Ppil4 peptidylprolyl isomerase like 4 increases expression ISO Pyrogallol results in increased expression of PPIL4 mRNA CTD PMID:20362636 NCBI chr 1:2,273,582...2,305,639
Ensembl chr 1:2,273,609...2,305,632 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO Pyrogallol results in increased expression of PRDX1 mRNA CTD PMID:20362636 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Pyrogallol results in increased expression of PRDX3 mRNA CTD PMID:20362636 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO Pyrogallol results in increased expression of PRDX6 mRNA CTD PMID:20362636 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of PSMC1 mRNA] CTD PMID:20362636 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Pyrogallol results in increased expression of PTGS2 protein] CTD PMID:35944648 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptov1 PTOV1, extended AT-hook containing adaptor protein increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of PTOV1 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of PTOV1 mRNA]		 CTD PMID:20362636 NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613 		JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4A2 increases expression ISO Pyrogallol results in increased expression of PTP4A2 mRNA CTD PMID:20362636 NCBI chr 5:142,165,405...142,192,412
Ensembl chr 5:142,165,700...142,191,899 		JBrowse link
G Pygl glycogen phosphorylase L increases expression ISO Pyrogallol results in increased expression of PYGL mRNA CTD PMID:20362636 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases expression ISO Pyrogallol results in increased expression of RAF1 mRNA CTD PMID:20362636 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 increases expression ISO Pyrogallol results in increased expression of RB1CC1 mRNA CTD PMID:20362636 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor increases expression ISO Pyrogallol results in increased expression of RBBP4 mRNA CTD PMID:20362636 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase increases expression ISO Pyrogallol results in increased expression of RBBP9 mRNA CTD PMID:20362636 NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156 		JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 increases expression ISO Pyrogallol results in increased expression of REPS1 mRNA CTD PMID:20362636 NCBI chr 1:12,697,742...12,775,562
Ensembl chr 1:12,697,747...12,775,561 		JBrowse link
G Rnf11 ring finger protein 11 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of RNF11 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of RNF11 mRNA]		 CTD PMID:20362636 NCBI chr 5:124,212,433...124,243,125
Ensembl chr 5:124,212,445...124,234,750 		JBrowse link
G Rnf4 ring finger protein 4 increases expression ISO Pyrogallol results in increased expression of RNF4 mRNA CTD PMID:20362636 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566 		JBrowse link
G Rogdi rogdi atypical leucine zipper multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of ROGDI mRNA] CTD PMID:20362636 NCBI chr10:10,567,834...10,572,453
Ensembl chr10:10,567,834...10,572,452 		JBrowse link
G Rpl10a ribosomal protein L10A increases expression ISO Pyrogallol results in increased expression of RPL10A mRNA CTD PMID:20362636 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357 		JBrowse link
G Rpl12 ribosomal protein L12 increases expression ISO Pyrogallol results in increased expression of RPL12 mRNA CTD PMID:20362636 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642 		JBrowse link
G Rpl23 ribosomal protein L23 increases expression ISO Pyrogallol results in increased expression of RPL23 mRNA CTD PMID:20362636 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl26 ribosomal protein L26 increases expression
decreases expression		 ISO Pyrogallol results in increased expression of RPL26 mRNA
Pyrogallol results in decreased expression of RPL26 mRNA		 CTD PMID:20362636 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Rpl31 ribosomal protein L31 increases expression
multiple interactions		 ISO Pyrogallol results in increased expression of RPL31 mRNA
Silymarin inhibits the reaction [Pyrogallol results in increased expression of RPL31 mRNA]		 CTD PMID:20362636 NCBI chr 9:41,647,397...41,651,441
Ensembl chr 9:41,647,426...41,662,129 		JBrowse link
G Rpl5 ribosomal protein L5 decreases expression
increases expression		 ISO Pyrogallol results in decreased expression of RPL5 mRNA
Pyrogallol results in increased expression of RPL5 mRNA		 CTD PMID:20362636 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rpl8 ribosomal protein L8 increases expression ISO Pyrogallol results in increased expression of RPL8 mRNA CTD PMID:20362636 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482 		JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO Pyrogallol results in decreased expression of RPS12 mRNA CTD PMID:20362636 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps20 ribosomal protein S20 increases expression ISO Pyrogallol results in increased expression of RPS20 mRNA CTD PMID:20362636 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475 		JBrowse link
G Rpsa ribosomal protein SA increases expression ISO Pyrogallol results in increased expression of RPSA mRNA CTD PMID:20362636 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Rras2 RAS related 2 increases expression ISO Pyrogallol results in increased expression of RRAS2 mRNA CTD PMID:20362636 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111 		JBrowse link
G Rtn4 reticulon 4 increases expression ISO Pyrogallol results in increased expression of RTN4 mRNA CTD PMID:20362636 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Pyrogallol results in increased expression of SARS1 mRNA CTD PMID:20362636 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Scamp2 secretory carrier membrane protein 2 increases expression ISO Pyrogallol results in increased expression of SCAMP2 mRNA CTD PMID:20362636 NCBI chr 8:57,965,612...57,992,248
Ensembl chr 8:57,965,631...57,992,646 		JBrowse link
G Scp2 sterol carrier protein 2 multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of SCP2 mRNA] CTD PMID:20362636 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A increases expression ISO Pyrogallol results in increased expression of SDHA mRNA CTD PMID:20362636 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Selenow selenoprotein W increases expression ISO Pyrogallol results in increased expression of SELENOW mRNA CTD PMID:20362636 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Senp6 SUMO specific peptidase 6 increases expression ISO Pyrogallol results in increased expression of SENP6 mRNA CTD PMID:20362636 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170 		JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression ISO Pyrogallol results in increased expression of SFPQ mRNA CTD PMID:20362636 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Slbp stem-loop histone mRNA binding protein increases expression ISO Pyrogallol results in increased expression of SLBP mRNA CTD PMID:20362636 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO Pyrogallol results in decreased expression of SLC12A2 mRNA CTD PMID:20362636 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Snca synuclein alpha multiple interactions ISO Pyrogallol inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Snta1 syntrophin, alpha 1 increases expression ISO Pyrogallol results in increased expression of SNTA1 mRNA CTD PMID:20362636 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709 		JBrowse link
G Snx9 sorting nexin 9 increases expression ISO Pyrogallol results in increased expression of SNX9 mRNA CTD PMID:20362636 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Socs6 suppressor of cytokine signaling 6 increases expression ISO Pyrogallol results in increased expression of SOCS6 mRNA CTD PMID:20362636 NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP Pyrogallol results in decreased activity of SOD1 protein CTD PMID:35944648 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Spr sepiapterin reductase increases expression ISO Pyrogallol results in increased expression of SPR mRNA CTD PMID:20362636 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of SPTLC1 mRNA] CTD PMID:20362636 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Ssbp3 single stranded DNA binding protein 3 increases expression ISO Pyrogallol results in increased expression of SSBP3 mRNA CTD PMID:20362636 NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of ST8SIA2 mRNA] CTD PMID:20362636 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G Stmn3 stathmin 3 increases expression ISO Pyrogallol results in increased expression of STMN3 mRNA CTD PMID:20362636 NCBI chr 3:168,416,810...168,424,946
Ensembl chr 3:168,416,810...168,425,056 		JBrowse link
G Strn4 striatin 4 increases expression ISO Pyrogallol results in increased expression of STRN4 mRNA CTD PMID:20362636 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858 		JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of SV2A mRNA] CTD PMID:20362636 NCBI chr 2:183,741,489...183,757,290
Ensembl chr 2:183,741,547...183,756,927 		JBrowse link
G Syt4 synaptotagmin 4 increases expression ISO Pyrogallol results in increased expression of SYT4 mRNA CTD PMID:20362636 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 increases expression ISO Pyrogallol results in increased expression of TDP2 mRNA CTD PMID:20362636 NCBI chr17:40,228,943...40,240,337
Ensembl chr17:40,228,947...40,240,313 		JBrowse link
G Tgoln2 trans-golgi network protein 2 increases expression ISO Pyrogallol results in increased expression of TGOLN1 mRNA CTD PMID:20362636 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164 		JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b increases expression ISO Pyrogallol results in increased expression of TIMM17B mRNA CTD PMID:20362636 NCBI chr  X:14,596,330...14,603,491
Ensembl chr  X:14,594,577...14,603,416 		JBrowse link
G Tirap TIR domain containing adaptor protein increases expression ISO Pyrogallol results in increased expression of TIRAP mRNA CTD PMID:20362636 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tnk2 tyrosine kinase, non-receptor, 2 increases expression ISO Pyrogallol results in increased expression of TNK2 mRNA CTD PMID:20362636 NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of TNNT1 mRNA] CTD PMID:20362636 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO pyrazolanthrone inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]; SB 203580 inhibits the reaction [Pyrogallol results in increased expression of TP53 protein] CTD PMID:20191265 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ubap2 ubiquitin-associated protein 2 increases expression ISO Pyrogallol results in increased expression of UBAP2 mRNA CTD PMID:20362636 NCBI chr 5:56,348,243...56,437,403
Ensembl chr 5:56,348,246...56,437,049 		JBrowse link
G Ubb ubiquitin B increases expression ISO Pyrogallol results in increased expression of UBB mRNA CTD PMID:20362636 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
G Ubc ubiquitin C increases expression ISO Pyrogallol results in increased expression of UBC mRNA CTD PMID:20362636 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ube4b ubiquitination factor E4B increases expression ISO Pyrogallol results in increased expression of UBE4B mRNA CTD PMID:20362636 NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression ISO Pyrogallol results in increased expression of UCHL1 mRNA CTD PMID:20362636 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO Pyrogallol results in increased expression of UGDH mRNA CTD PMID:20362636 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 increases expression ISO Pyrogallol results in increased expression of USP10 mRNA CTD PMID:20362636 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression ISO Pyrogallol results in increased expression of VDAC1 mRNA CTD PMID:20362636 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vim vimentin multiple interactions
increases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in increased expression of VIM mRNA] CTD PMID:20362636 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vps26c VPS26 endosomal protein sorting factor C multiple interactions
decreases expression		 ISO Silymarin inhibits the reaction [Pyrogallol results in decreased expression of VPS26C mRNA] CTD PMID:20362636 NCBI chr11:33,813,467...33,841,883
Ensembl chr11:33,792,389...33,841,447 		JBrowse link
G Vps72 vacuolar protein sorting 72 homolog decreases expression
multiple interactions		 ISO Pyrogallol results in decreased expression of VPS72 mRNA
Silymarin inhibits the reaction [Pyrogallol results in decreased expression of VPS72 mRNA]		 CTD PMID:20362636 NCBI chr 2:182,678,594...182,690,185
Ensembl chr 2:182,678,609...182,690,182 		JBrowse link
G Zfp91 zinc finger protein 91 increases expression ISO Pyrogallol results in increased expression of ZFP91 mRNA CTD PMID:20362636 NCBI chr 1:209,891,344...209,928,890
Ensembl chr 1:209,891,344...209,927,762 		JBrowse link
resorcinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acyp1 acylphosphatase 1 increases expression ISO resorcinol results in increased expression of ACYP1 mRNA CTD PMID:22623647 NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387 		JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO resorcinol affects the activity of AHR protein CTD PMID:18294747 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO resorcinol results in increased expression of AKAP12 mRNA CTD PMID:22623647 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO resorcinol results in increased expression of AKR1B10 mRNA CTD PMID:22623647 PMID:26198647 PMID:30806763 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO resorcinol results in increased expression of AKR1C1 mRNA CTD PMID:30806763 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]
resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein]		 CTD PMID:26262998 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 increases expression ISO resorcinol results in increased expression of ANKRD37 mRNA CTD PMID:22623647 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 decreases expression ISO resorcinol results in decreased expression of APBB2 mRNA CTD PMID:22623647 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495 		JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions ISO resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein] CTD PMID:26262998 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO resorcinol results in increased expression of AQP3 mRNA CTD PMID:22623647 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Ar androgen receptor affects activity ISO resorcinol affects the activity of AR protein CTD PMID:18294747 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO resorcinol results in decreased expression of ARRDC3 mRNA CTD PMID:22623647 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO resorcinol results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf7ip activating transcription factor 7 interacting protein decreases expression ISO resorcinol results in decreased expression of ATF7IP mRNA CTD PMID:22623647 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650 		JBrowse link
G Atxn7l3b ataxin 7-like 3B increases expression ISO resorcinol results in increased expression of ATXN7L3B mRNA CTD PMID:22623647 NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor decreases expression ISO resorcinol results in decreased expression of BAMBI mRNA CTD PMID:22623647 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO resorcinol results in increased expression of BHLHE40 mRNA CTD PMID:22623647 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Blcap BLCAP, apoptosis inducing factor increases expression ISO resorcinol results in increased expression of BLCAP mRNA CTD PMID:22623647 NCBI chr 3:146,222,699...146,232,859
Ensembl chr 3:146,222,240...146,232,909 		JBrowse link
G Brox BRO1 domain and CAAX motif containing decreases expression ISO resorcinol results in decreased expression of BROX mRNA CTD PMID:22623647 NCBI chr13:94,920,107...94,940,189
Ensembl chr13:94,920,112...94,940,227 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO resorcinol results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421 		JBrowse link
G C10h17orf100 similar to human chromosome 17 open reading frame 100 increases expression ISO resorcinol results in increased expression of C17ORF100 mRNA CTD PMID:22623647 NCBI chr10:56,840,451...56,843,674
Ensembl chr10:56,832,412...56,843,871 		JBrowse link
G C15h14orf119 similar to human chromosome 14 open reading frame 119 increases expression ISO resorcinol results in increased expression of C14ORF119 mRNA CTD PMID:22623647 NCBI chr15:28,146,368...28,151,422
Ensembl chr15:28,146,333...28,155,180 		JBrowse link
G C2h4orf3 similar to human chromosome 4 open reading frame 3 increases expression ISO resorcinol results in increased expression of C4ORF3 mRNA CTD PMID:22623647 NCBI chr 2:211,055,925...211,057,685
Ensembl chr 2:211,055,911...211,057,681 		JBrowse link
G C2h4orf46 similar to human chromosome 4 open reading frame 46 increases expression ISO resorcinol results in increased expression of C4ORF46 mRNA CTD PMID:22623647 NCBI chr 2:164,762,994...164,766,126
Ensembl chr 2:164,762,960...164,766,128 		JBrowse link
G C2h5orf34 similar to human chromosome 5 open reading frame 34 decreases expression ISO resorcinol results in decreased expression of C5ORF34 mRNA CTD PMID:22623647 NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085 		JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression ISO resorcinol results in decreased expression of C5AR1 mRNA CTD PMID:22623647 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Carf calcium responsive transcription factor decreases expression ISO resorcinol results in decreased expression of CARF mRNA CTD PMID:22623647 NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO resorcinol results in increased expression of CCR7 mRNA CTD PMID:21697260 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Cct6b chaperonin containing TCP1 subunit 6B decreases expression ISO resorcinol results in decreased expression of CCT6B mRNA CTD PMID:22623647 NCBI chr10:67,652,461...67,701,385
Ensembl chr10:67,652,546...67,701,284 		JBrowse link
G Cd83 CD83 molecule increases expression ISO resorcinol results in increased expression of CD83 protein CTD PMID:21697260 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO resorcinol results in decreased expression of CDC20 mRNA CTD PMID:22623647 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc40 cell division cycle 40 decreases expression ISO resorcinol results in decreased expression of CDC40 mRNA CTD PMID:22623647 NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO resorcinol results in increased expression of CITED2 mRNA CTD PMID:22623647 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cldn1 claudin 1 decreases expression ISO resorcinol results in decreased expression of CLDN1 mRNA CTD PMID:22623647 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Colec11 collectin sub-family member 11 decreases expression ISO resorcinol results in decreased expression of COLEC11 mRNA CTD PMID:22623647 NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO resorcinol results in decreased expression of CXCL2 mRNA CTD PMID:22623647 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO resorcinol results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxhxorf38 similar to human chromosome X open reading frame 38 decreases expression ISO resorcinol results in decreased expression of CXORF38 mRNA CTD PMID:22623647 NCBI chr  X:10,128,070...10,150,904
Ensembl chr  X:10,129,657...10,150,900 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO resorcinol results in increased expression of CYP1A1 mRNA CTD PMID:30806763 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dct dopachrome tautomerase decreases expression ISO resorcinol results in decreased expression of DCT mRNA; resorcinol results in decreased expression of DCT protein CTD PMID:29621941 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO resorcinol results in decreased expression of DDIT3 mRNA CTD PMID:22623647 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 increases expression ISO resorcinol results in increased expression of DEGS1 mRNA CTD PMID:22623647 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression ISO resorcinol results in decreased expression of DNAJB1 mRNA CTD PMID:22623647 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO resorcinol results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 decreases expression ISO resorcinol results in decreased expression of DNAJC27 mRNA CTD PMID:22623647 NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO resorcinol results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp15 dual specificity phosphatase 15 decreases expression ISO resorcinol results in decreased expression of DUSP15 mRNA CTD PMID:22623647 NCBI chr 3:141,408,495...141,419,137
Ensembl chr 3:141,408,498...141,418,999 		JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO resorcinol results in increased expression of DUSP5 mRNA CTD PMID:22623647 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dynll2 dynein light chain LC8-type 2 decreases expression ISO resorcinol results in decreased expression of DYNLL2 mRNA CTD PMID:22623647 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805 		JBrowse link
G Efcab8 EF-hand calcium binding domain 8 increases expression ISO resorcinol results in increased expression of EFCAB8 mRNA CTD PMID:22623647 NCBI chr 3:142,257,195...142,323,743
Ensembl chr 3:142,257,229...142,323,743 		JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 increases expression ISO resorcinol results in increased expression of EID2 mRNA CTD PMID:22623647 NCBI chr 1:83,538,274...83,539,599 JBrowse link
G Eno2 enolase 2 increases expression ISO resorcinol results in increased expression of ENO2 mRNA CTD PMID:22623647 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO resorcinol results in decreased expression of ERO1B mRNA CTD PMID:22623647 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398 		JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO resorcinol binds to ESR1 protein CTD PMID:12598185 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO resorcinol results in increased expression of FAM13A mRNA CTD PMID:22623647 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Fam241a family with sequence similarity 241 member A increases expression ISO resorcinol results in increased expression of FAM241A mRNA CTD PMID:22623647 NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242 		JBrowse link
G Fancl FA complementation group L increases expression ISO resorcinol results in increased expression of FANCL mRNA CTD PMID:22623647 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255 		JBrowse link
G Fastkd5 FAST kinase domains 5 increases expression ISO resorcinol results in increased expression of FASTKD5 mRNA CTD PMID:22623647 NCBI chr 3:117,830,219...117,847,707
Ensembl chr 3:117,830,083...117,847,820 		JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 decreases expression ISO resorcinol results in decreased expression of FBXL20 mRNA CTD PMID:22623647 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162 		JBrowse link
G Fbxo30 F-box protein 30 increases expression ISO resorcinol results in increased expression of FBXO30 mRNA CTD PMID:26198647 NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441 		JBrowse link
G Fbxo36 F-box protein 36 decreases expression ISO resorcinol results in decreased expression of FBXO36 mRNA CTD PMID:22623647 NCBI chr 9:86,042,522...86,107,220
Ensembl chr 9:86,040,862...86,107,229 		JBrowse link
G Frk fyn-related Src family tyrosine kinase decreases expression ISO resorcinol results in decreased expression of FRK mRNA CTD PMID:22623647 NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114 		JBrowse link
G Fzd7 frizzled class receptor 7 increases expression ISO resorcinol results in increased expression of FZD7 mRNA CTD PMID:22623647 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO resorcinol results in decreased expression of GADD45B mRNA CTD PMID:22623647 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gan gigaxonin decreases expression ISO resorcinol results in decreased expression of GAN mRNA CTD PMID:22623647 NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO resorcinol results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gin1 gypsy retrotransposon integrase 1 decreases expression ISO resorcinol results in decreased expression of GIN1 mRNA CTD PMID:22623647 NCBI chr 9:98,293,596...98,315,155
Ensembl chr 9:98,293,597...98,315,848 		JBrowse link
G Glce glucuronic acid epimerase increases expression ISO resorcinol results in increased expression of GLCE mRNA CTD PMID:22623647 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040 		JBrowse link
G Gpatch11 G patch domain containing 11 decreases expression ISO resorcinol results in decreased expression of GPATCH11 mRNA CTD PMID:22623647 NCBI chr 6:16,229,933...16,243,305
Ensembl chr 6:16,233,059...16,243,238 		JBrowse link
G Gpatch2 G patch domain containing 2 decreases expression ISO resorcinol results in decreased expression of GPATCH2 mRNA CTD PMID:22623647 NCBI chr13:98,784,993...98,925,696
Ensembl chr13:98,784,969...98,925,661 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO resorcinol results in decreased expression of GPCPD1 mRNA CTD PMID:22623647 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Gpnmb glycoprotein nmb increases expression
decreases expression		 ISO resorcinol results in increased expression of GPNMB mRNA
resorcinol results in decreased expression of GPNMB protein		 CTD PMID:22623647 PMID:29621941 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO resorcinol results in increased expression of H2AX mRNA CTD PMID:22623647 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO resorcinol results in increased expression of HILPDA mRNA CTD PMID:22623647 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 decreases expression ISO resorcinol results in decreased expression of HINT3 mRNA CTD PMID:22623647 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO resorcinol results in increased expression of HMOX1 mRNA CTD PMID:30806763 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 increases expression ISO resorcinol results in increased expression of HNRNPH2 mRNA CTD PMID:22623647 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041 		JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 increases expression ISO resorcinol results in increased expression of HNRNPH3 mRNA CTD PMID:22623647 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750 		JBrowse link
G Hoxd1 homeo box D1 increases expression ISO resorcinol results in increased expression of HOXD1 mRNA CTD PMID:22623647 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769 		JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 decreases expression ISO resorcinol results in decreased expression of HS3ST3B1 mRNA CTD PMID:22623647 NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO resorcinol results in decreased expression of HSPA1A mRNA CTD PMID:22623647 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO resorcinol results in decreased expression of HSPA1B mRNA CTD PMID:22623647 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like decreases expression ISO resorcinol results in decreased expression of HSPA4L mRNA CTD PMID:22623647 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO resorcinol results in increased expression of ICAM1 mRNA; resorcinol results in increased expression of ICAM1 protein CTD PMID:30806763 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression ISO resorcinol analog results in decreased expression of ID1 protein CTD PMID:24910342 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO resorcinol analog results in increased expression of ID2 protein CTD PMID:24910342 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO resorcinol results in decreased expression of ID3 mRNA CTD PMID:22623647 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO resorcinol results in increased expression of IDI1 mRNA CTD PMID:22623647 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ikzf5 IKAROS family zinc finger 5 decreases expression ISO resorcinol results in decreased expression of IKZF5 mRNA CTD PMID:22623647 NCBI chr 1:186,169,108...186,188,847
Ensembl chr 1:186,170,788...186,188,834 		JBrowse link
G Il18 interleukin 18 increases expression ISO resorcinol results in increased expression of IL18 mRNA; resorcinol results in increased expression of IL18 protein CTD PMID:23063874 PMID:30806763 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO resorcinol results in increased expression of IL1A mRNA CTD PMID:30806763 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO resorcinol results in increased expression of IL1B mRNA CTD PMID:21697260 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO resorcinol results in increased expression of IL1R2 mRNA CTD PMID:30806763 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Ing3 inhibitor of growth family, member 3 decreases expression ISO resorcinol results in decreased expression of ING3 mRNA CTD PMID:22623647 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715 		JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO resorcinol results in increased expression of INSIG2 mRNA CTD PMID:22623647 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 decreases expression ISO resorcinol results in decreased expression of IRAK1BP1 mRNA CTD PMID:22623647 NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289 		JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO resorcinol results in decreased expression of JDP2 mRNA CTD PMID:22623647 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485 		JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor decreases expression ISO resorcinol results in decreased expression of JMY mRNA CTD PMID:22623647 NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006 		JBrowse link
G Khdc4 KH domain containing 4, pre-mRNA splicing factor increases expression ISO resorcinol results in increased expression of KHDC4 mRNA CTD PMID:22623647 NCBI chr 2:174,149,059...174,177,816
Ensembl chr 2:174,149,141...174,177,504 		JBrowse link
G Klhl11 kelch-like family member 11 decreases expression ISO resorcinol results in decreased expression of KLHL11 mRNA CTD PMID:22623647 NCBI chr10:85,398,487...85,409,049
Ensembl chr10:85,398,487...85,409,049 		JBrowse link
G Leng8 leukocyte receptor cluster member 8 increases expression ISO resorcinol results in increased expression of LENG8 mRNA CTD PMID:22623647 NCBI chr 1:70,040,785...70,052,662
Ensembl chr 1:70,040,785...70,052,488 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO resorcinol results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lin54 lin-54 DREAM MuvB core complex component increases expression ISO resorcinol results in increased expression of LIN54 mRNA CTD PMID:22623647 NCBI chr14:9,129,775...9,188,244
Ensembl chr14:9,130,336...9,187,790 		JBrowse link
G Lipg lipase G, endothelial type increases expression ISO resorcinol results in increased expression of LIPG mRNA CTD PMID:22623647 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Llph LLP homolog, long-term synaptic facilitation factor increases expression ISO resorcinol results in increased expression of LLPH mRNA CTD PMID:22623647 NCBI chr 7:55,735,317...55,740,341
Ensembl chr 7:55,735,400...55,740,339 		JBrowse link
G LOC100909998 zinc finger protein 2-like decreases expression ISO resorcinol results in decreased expression of ZNF2 mRNA CTD PMID:22623647 NCBI chr 3:114,793,783...114,818,395
Ensembl chr 3:114,809,723...114,818,387
Ensembl chr 3:114,809,723...114,818,387 		JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 increases expression ISO resorcinol results in increased expression of LPAR6 mRNA CTD PMID:22623647 NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331 		JBrowse link
G Lpxn leupaxin decreases expression ISO resorcinol results in decreased expression of LPXN mRNA CTD PMID:22623647 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084 		JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO resorcinol results in decreased expression of LRIG3 mRNA CTD PMID:22623647 NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481 		JBrowse link
G Lrrc8d leucine rich repeat containing 8 VRAC subunit D decreases expression ISO resorcinol results in decreased expression of LRRC8D mRNA CTD PMID:22623647 NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877 		JBrowse link
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor increases expression ISO resorcinol results in increased expression of LUC7L3 mRNA CTD PMID:22623647 NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases lipidation ISO resorcinol analog results in increased lipidation of MAP1LC3A protein CTD PMID:24910342 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 decreases expression ISO resorcinol results in decreased expression of MAP3K13 mRNA CTD PMID:22623647 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Mfsd9 major facilitator superfamily domain containing 9 decreases expression ISO resorcinol results in decreased expression of MFSD9 mRNA CTD PMID:22623647 NCBI chr 9:43,019,611...43,039,100
Ensembl chr 9:43,019,618...43,039,176 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO resorcinol results in decreased expression of MITF mRNA; resorcinol results in decreased expression of MITF protein CTD PMID:25584612 PMID:29621941 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO resorcinol results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO resorcinol results in increased expression of MMP3 mRNA CTD PMID:30806763 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO resorcinol results in increased expression of MOAP1 mRNA CTD PMID:22623647 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein]
resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]		 CTD PMID:26262998 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 increases expression ISO resorcinol results in increased expression of MRPL50 mRNA CTD PMID:22623647 NCBI chr 5:63,867,437...63,872,591 JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 decreases expression ISO resorcinol results in decreased expression of N6AMT1 mRNA CTD PMID:22623647 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression ISO resorcinol results in increased expression of NANOS1 mRNA CTD PMID:22623647 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730 		JBrowse link
G Ncbp2as2 NCBP2 antisense 2 (head to head) increases expression ISO resorcinol results in increased expression of NCBP2AS2 mRNA CTD PMID:22623647 NCBI chr11:68,829,950...68,830,715
Ensembl chr11:68,829,983...68,830,708 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO resorcinol results in increased expression of NDRG1 mRNA CTD PMID:22623647 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nexn nexilin (F actin binding protein) decreases expression ISO resorcinol results in decreased expression of NEXN mRNA CTD PMID:22623647 NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342 		JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein increases expression ISO resorcinol results in increased expression of NFATC2IP mRNA CTD PMID:22623647 NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO resorcinol results in decreased expression of NFE2L2 mRNA CTD PMID:31967339 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO resorcinol results in increased expression of NQO1 mRNA CTD PMID:30806763 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO resorcinol results in increased expression of NR0B2 mRNA CTD PMID:22623647 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr6a1 nuclear receptor subfamily 6, group A, member 1 decreases expression ISO resorcinol results in decreased expression of NR6A1 mRNA CTD PMID:22623647 NCBI chr 3:22,495,109...22,683,132
Ensembl chr 3:22,496,943...22,683,131 		JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 decreases expression ISO resorcinol results in decreased expression of NSUN3 mRNA CTD PMID:22623647 NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression ISO resorcinol results in decreased expression of NUPR1 mRNA CTD PMID:22623647 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO resorcinol results in increased expression of PFKFB3 mRNA CTD PMID:22623647 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 increases expression ISO resorcinol results in increased expression of PGRMC2 mRNA CTD PMID:22623647 NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155 		JBrowse link
G Plpp6 phospholipid phosphatase 6 increases expression ISO resorcinol results in increased expression of PLPP6 mRNA CTD PMID:22623647 NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949 		JBrowse link
G Pnisr PNN interacting serine and arginine rich protein increases expression ISO resorcinol results in increased expression of PNISR mRNA CTD PMID:22623647 NCBI chr 5:35,395,965...35,422,852
Ensembl chr 5:35,395,965...35,422,844 		JBrowse link
G Pnma1 PNMA family member 1 increases expression ISO resorcinol results in increased expression of PNMA1 mRNA CTD PMID:22623647 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567 		JBrowse link
G Pnn pinin, desmosome associated protein increases expression ISO resorcinol results in increased expression of PNN mRNA CTD PMID:22623647 NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889 		JBrowse link
G Prrg1 proline rich and Gla domain 1 increases expression ISO resorcinol results in increased expression of PRRG1 mRNA CTD PMID:22623647 NCBI chr  X:42,494,256...42,606,612
Ensembl chr  X:42,494,256...42,606,588 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form] CTD PMID:26262998 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO resorcinol results in increased expression of PTGR1 mRNA CTD PMID:22623647 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgr3 prostaglandin reductase 3 increases expression ISO resorcinol results in increased expression of PTGR3 mRNA CTD PMID:22623647 NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression		 ISO resorcinol inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA]
resorcinol results in increased expression of PTGS2 mRNA
resorcinol results in decreased expression of PTGS2 mRNA		 CTD PMID:10783318 PMID:30806763 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rab42 RAB42, member RAS oncogene family increases expression ISO resorcinol results in increased expression of RAB42 mRNA CTD PMID:22623647 NCBI chr 5:144,497,159...144,498,829
Ensembl chr 5:144,496,215...144,498,848 		JBrowse link
G Rbm12 RNA binding motif protein 12 increases expression ISO resorcinol results in increased expression of RBM12 mRNA CTD PMID:22623647 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Rgcc regulator of cell cycle increases expression ISO resorcinol results in increased expression of RGCC mRNA CTD PMID:22623647 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Rlim ring finger protein, LIM domain interacting decreases expression ISO resorcinol results in decreased expression of RLIM mRNA CTD PMID:22623647 NCBI chr  X:68,983,259...69,004,368
Ensembl chr  X:68,988,375...69,004,271 		JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression ISO resorcinol results in decreased expression of RND1 mRNA CTD PMID:22623647 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399 		JBrowse link
G Rraga Ras-related GTP binding A increases expression ISO resorcinol results in increased expression of RRAGA mRNA CTD PMID:22623647 NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510 		JBrowse link
G Rsrp1 arginine and serine rich protein 1 increases expression ISO resorcinol results in increased expression of RSRP1 mRNA CTD PMID:22623647 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523 		JBrowse link
G Samd4a sterile alpha motif domain containing 4A decreases expression ISO resorcinol results in decreased expression of SAMD4A mRNA CTD PMID:22623647 NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380 		JBrowse link
G Sdsl serine dehydratase-like decreases expression ISO resorcinol results in decreased expression of SDSL mRNA CTD PMID:22623647 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906 		JBrowse link
G Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase decreases expression ISO resorcinol results in decreased expression of SEPSECS mRNA CTD PMID:22623647 NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740 		JBrowse link
G Serpinb3 serpin family B member 3 increases expression ISO resorcinol results in increased expression of SERPINB3 mRNA CTD PMID:30806763 NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682 		JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO resorcinol results in increased expression of SERPINB9 mRNA CTD PMID:22623647 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Sesn3 sestrin 3 decreases expression ISO resorcinol results in decreased expression of SESN3 mRNA CTD PMID:22623647 NCBI chr 8:11,133,822...11,189,436
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
G Skil SKI-like proto-oncogene decreases expression ISO resorcinol results in decreased expression of SKIL mRNA CTD PMID:22623647 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Slc17a2 solute carrier family 17, member 2 decreases expression ISO resorcinol results in decreased expression of SLC17A2 mRNA CTD PMID:22623647 NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO resorcinol results in increased expression of SLC2A3 mRNA CTD PMID:22623647 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc44a2 solute carrier family 44 member 2 decreases expression ISO resorcinol results in decreased expression of SLC44A2 mRNA CTD PMID:22623647 NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342 		JBrowse link
G Slc51b SLC51 subunit beta decreases expression ISO resorcinol results in decreased expression of SLC51B mRNA CTD PMID:22623647 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc6a8 solute carrier family 6 member 8 increases expression ISO resorcinol results in increased expression of SLC6A8 mRNA CTD PMID:22623647 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO resorcinol results in decreased expression of SLC7A11 mRNA CTD PMID:22623647 PMID:26198647 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Smad7 SMAD family member 7 decreases expression ISO resorcinol results in decreased expression of SMAD7 mRNA CTD PMID:22623647 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smim19 small integral membrane protein 19 decreases expression ISO resorcinol results in decreased expression of SMIM19 mRNA CTD PMID:22623647 NCBI chr16:69,551,507...69,564,323
Ensembl chr16:69,553,916...69,567,245 		JBrowse link
G Snora61 small nucleolar RNA, H/ACA box 61 increases expression ISO resorcinol results in increased expression of SNORA61 mRNA CTD PMID:22623647 NCBI chr 5:144,506,420...144,506,549
Ensembl chr 5:144,506,420...144,506,549 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 decreases expression ISO resorcinol results in decreased expression of SOCS7 mRNA CTD PMID:22623647 NCBI chr10:82,352,159...82,388,829
Ensembl chr10:82,351,680...82,388,830 		JBrowse link
G Spin4 spindlin family, member 4 increases expression ISO resorcinol results in increased expression of SPIN4 mRNA CTD PMID:22623647 NCBI chr  X:59,888,728...59,892,817
Ensembl chr  X:59,891,581...59,892,330 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A increases expression ISO resorcinol results in increased expression of SPTSSA mRNA CTD PMID:22623647 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO resorcinol results in increased expression of SRSF5 mRNA CTD PMID:22623647 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO resorcinol results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Stbd1 starch binding domain 1 increases expression ISO resorcinol results in increased expression of STBD1 mRNA CTD PMID:22623647 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443 		JBrowse link
G Stk17b serine/threonine kinase 17b decreases expression ISO resorcinol results in decreased expression of STK17B mRNA CTD PMID:22623647 NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:55,307,668...55,338,031 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO resorcinol results in increased expression of TAF7 mRNA CTD PMID:22623647 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 increases expression ISO resorcinol results in increased expression of TAFA5 mRNA CTD PMID:22623647 NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353 		JBrowse link
G Tagln transgelin decreases expression ISO resorcinol results in decreased expression of TAGLN mRNA CTD PMID:22623647 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tatdn3 TatD DNase domain containing 3 decreases expression ISO resorcinol results in decreased expression of TATDN3 mRNA CTD PMID:22623647 NCBI chr13:102,634,254...102,649,069
Ensembl chr13:102,634,258...102,649,063 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 increases expression ISO resorcinol results in increased expression of TET1 mRNA CTD PMID:22623647 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO resorcinol inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA] CTD PMID:10783318 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression ISO resorcinol results in increased expression of TIMM10B mRNA CTD PMID:22623647 NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642 		JBrowse link
G Tmcc1 transmembrane and coiled-coil domain family 1 increases expression ISO resorcinol results in increased expression of TMCC1 mRNA CTD PMID:22623647 NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620 		JBrowse link
G Tmem169 transmembrane protein 169 decreases expression ISO resorcinol results in decreased expression of TMEM169 mRNA CTD PMID:22623647 NCBI chr 9:73,926,553...73,950,679
Ensembl chr 9:73,926,568...73,950,576 		JBrowse link
G Tmem170a transmembrane protein 170A decreases expression ISO resorcinol results in decreased expression of TMEM170A mRNA CTD PMID:22623647 NCBI chr19:39,833,947...39,846,807
Ensembl chr19:39,833,980...39,846,783 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO resorcinol results in increased expression of TNF mRNA CTD PMID:30806763 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53inp2 tumor protein p53 inducible nuclear protein 2 increases expression ISO resorcinol results in increased expression of TP53INP2 mRNA CTD PMID:22623647 NCBI chr 3:143,881,427...143,890,104
Ensembl chr 3:143,882,021...143,890,097 		JBrowse link
G Tpo thyroid peroxidase multiple interactions
decreases activity		 ISO
EXP		 resorcinol binds to and results in decreased activity of TPO protein
resorcinol results in decreased activity of TPO protein		 CTD PMID:26865668 PMID:31629072 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Trim50 tripartite motif-containing 50 decreases expression ISO resorcinol results in decreased expression of TRIM50 mRNA CTD PMID:22623647 NCBI chr12:21,300,784...21,317,668
Ensembl chr12:21,300,785...21,317,668 		JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO resorcinol results in increased expression of TUBA4A mRNA CTD PMID:22623647 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918 		JBrowse link
G Tubb1 tubulin, beta 1 class VI increases expression ISO resorcinol results in increased expression of TUBB1 mRNA CTD PMID:22623647 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb increases expression ISO resorcinol results in increased expression of TUBB4B mRNA CTD PMID:22623647 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tuft1 tuftelin 1 decreases expression ISO resorcinol results in decreased expression of TUFT1 mRNA CTD PMID:22623647 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO resorcinol results in increased expression of TXNRD1 mRNA CTD PMID:30806763 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Tyr tyrosinase decreases activity
multiple interactions
decreases expression		 ISO resorcinol results in decreased activity of TYR protein
[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein; resorcinol results in decreased expression of and results in decreased activity of TYR protein; SB 203580 inhibits the reaction [[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein]; SB 203580 inhibits the reaction [resorcinol results in decreased activity of TYR protein]
resorcinol results in decreased expression of TYR mRNA; resorcinol results in decreased expression of TYR protein		 CTD PMID:25584612 PMID:29621941 PMID:30849679 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO resorcinol results in decreased expression of TYRP1 mRNA; resorcinol results in decreased expression of TYRP1 protein CTD PMID:29621941 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Ubqln2 ubiquilin 2 increases expression ISO resorcinol results in increased expression of UBQLN2 mRNA CTD PMID:22623647 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
G Wdcp WD repeat and coiled coil containing increases expression ISO resorcinol results in increased expression of WDCP mRNA CTD PMID:22623647 NCBI chr 6:27,850,684...27,865,540
Ensembl chr 6:27,850,698...27,865,536 		JBrowse link
G Yju2b YJU2 splicing factor homolog B decreases expression ISO resorcinol results in decreased expression of YJU2B mRNA CTD PMID:22623647 NCBI chr19:23,894,587...23,906,084
Ensembl chr19:23,894,649...23,906,077 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression ISO resorcinol results in decreased expression of ZBTB20 mRNA CTD PMID:22623647 NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210 		JBrowse link
G Zbtb37 zinc finger and BTB domain containing 37 decreases expression ISO resorcinol results in decreased expression of ZBTB37 mRNA CTD PMID:22623647 NCBI chr13:73,271,920...73,303,427
Ensembl chr13:73,280,544...73,337,124 		JBrowse link
G Zfp347 zinc finger protein 347 decreases expression ISO resorcinol results in decreased expression of ZNF14 mRNA CTD PMID:22623647 NCBI chr 7:7,460,543...7,479,378
Ensembl chr 7:7,459,701...7,484,430 		JBrowse link
G Zfp35 zinc finger protein 35 decreases expression ISO resorcinol results in decreased expression of ZNF79 mRNA CTD PMID:22623647 NCBI chr18:15,268,852...15,284,334
Ensembl chr18:15,268,814...15,285,088 		JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 increases expression ISO resorcinol results in increased expression of ZFYVE26 mRNA CTD PMID:22623647 NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480 		JBrowse link
G Zic2 Zic family member 2 increases expression ISO resorcinol results in increased expression of ZIC2 mRNA CTD PMID:22623647 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
G Znf8 zinc finger protein 8 decreases expression ISO resorcinol results in decreased expression of ZNF8 mRNA CTD PMID:22623647 NCBI chr 1:73,498,526...73,511,929
Ensembl chr 1:73,498,491...73,511,119 		JBrowse link
Sudan I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5a cytochrome b5 type A multiple interactions EXP
ISO		 CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]
CYB5A protein inhibits the reaction [CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein inhibits the reaction [CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein inhibits the reaction [CYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP2A6 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYB5A protein promotes the reaction [CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol]		 CTD PMID:17159775 PMID:19358889 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases oxidation		 ISO
EXP		 CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYP1A1 protein results in increased metabolism of and results in increased activity of 1-phenylazo-2-naphthol
1-phenylazo-2-naphthol results in increased expression of CYP1A1 mRNA; 1-phenylazo-2-naphthol results in increased expression of CYP1A1 protein
1-phenylazo-2-naphthol promotes the reaction [aristolochic acid I results in increased expression of and results in increased activity of CYP1A1 protein]; 1-phenylazo-2-naphthol results in increased expression of and results in increased activity of CYP1A1 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A1 mRNA; [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1-phenylazo-2-naphthol; CYB5A protein promotes the reaction [CYP1A1 protein results in increased oxidation of 1-phenylazo-2-naphthol]; CYP1A1 protein results in increased metabolism of and results in increased activity of 1-phenylazo-2-naphthol		 CTD PMID:12384524 PMID:15766589 PMID:17159775 PMID:18418879 PMID:23289503 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
increases oxidation		 ISO
EXP		 CYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol]
1-phenylazo-2-naphthol results in increased expression of CYP1A2 mRNA
1-phenylazo-2-naphthol affects the expression of and affects the activity of CYP1A2 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA; [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of CYP1A2 protein		 CTD PMID:17159775 PMID:26845733 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases oxidation ISO CYP1B1 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases oxidation
multiple interactions		 ISO CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol
CYB5A protein inhibits the reaction [CYP2B6 protein results in increased oxidation of 1-phenylazo-2-naphthol]		 CTD PMID:17159775 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity
multiple interactions		 EXP 1-phenylazo-2-naphthol results in decreased activity of CYP2C11 protein
[aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in decreased activity of CYP2C11 protein		 CTD PMID:26845733 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
increases oxidation		 ISO CYB5A protein inhibits the reaction [CYP2C19 protein results in increased oxidation of 1-phenylazo-2-naphthol] CTD PMID:17159775 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases oxidation ISO CYP2C8 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
increases oxidation		 ISO CYB5A protein inhibits the reaction [CYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphthol] CTD PMID:17159775 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases oxidation
multiple interactions		 ISO CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol
CYB5A protein promotes the reaction [CYP3A4 protein results in increased oxidation of 1-phenylazo-2-naphthol]		 CTD PMID:17159775 PMID:19358889 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO 1-phenylazo-2-naphthol results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 1-phenylazo-2-naphthol results in increased expression of GSTP1 mRNA CTD PMID:2563599 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression		 EXP 1-phenylazo-2-naphthol results in increased expression of and results in increased activity of NQO1 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of NQO1 mRNA; [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of NQO1 protein
1-phenylazo-2-naphthol results in increased expression of NQO1 mRNA		 CTD PMID:23289503 PMID:26845733 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1-phenylazo-2-naphthol CTD PMID:24530354 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
Sudan III term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions		 ISO
EXP		 sudan III affects the localization of AHR protein
[sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased activity of CYP2C11 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A23-3A1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 protein]; [sudan III binds to AHR protein] which results in decreased activity of CYP2C11 protein; sudan III binds to and results in increased activity of AHR protein
[sudan III affects the localization of AHR protein] promotes the reaction [AHR protein binds to ARNT protein]; [sudan III affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; sudan III binds to and results in increased activity of AHR protein		 CTD PMID:15585952 PMID:15788368 PMID:22287322 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO [sudan III affects the localization of AHR protein] promotes the reaction [AHR protein binds to ARNT protein] CTD PMID:22287322 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
increases activity
multiple interactions		 ISO
EXP		 sudan III results in increased expression of CYP1A1 mRNA
sudan III results in increased expression of CYP1A1 mRNA; sudan III results in increased expression of CYP1A1 protein
sudan III results in increased activity of CYP1A1 protein
[sudan III affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; NR1I3 protein promotes the reaction [sudan III results in increased expression of CYP1A1 mRNA]		 CTD PMID:18418879 PMID:20308224 PMID:22287322 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP sudan III results in increased expression of CYP1A2 protein CTD PMID:20308224 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression		 EXP [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 protein]; sudan III results in decreased expression of and results in decreased activity of CYP2B1 protein
sudan III results in decreased expression of CYP2B1 mRNA		 CTD PMID:15788368 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions
decreases expression		 EXP [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 protein]; sudan III results in decreased expression of and results in decreased activity of CYP2B2 protein
sudan III results in decreased expression of CYP2B2 mRNA		 CTD PMID:15788368 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
decreases expression		 EXP [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased activity of CYP2C11 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 protein]; [sudan III binds to AHR protein] which results in decreased activity of CYP2C11 protein; sudan III results in decreased expression of and results in decreased activity of CYP2C11 protein
sudan III results in decreased expression of CYP2C11 mRNA		 CTD PMID:15788368 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression		 EXP [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 protein]; sudan III results in decreased expression of and results in decreased activity of CYP3A2 protein
sudan III results in decreased expression of CYP3A2 mRNA		 CTD PMID:15788368 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
decreases expression		 EXP [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A23-3A1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 protein]; sudan III results in decreased expression of and results in decreased activity of CYP3A23-3A1 protein
sudan III results in decreased expression of CYP3A23-3A1 mRNA		 CTD PMID:15788368 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP sudan III results in decreased expression of CYP4A1 mRNA CTD PMID:15585952 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression EXP sudan III results in decreased expression of CYP4A2 mRNA CTD PMID:15585952 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP sudan III results in decreased expression of CYP4A3 mRNA CTD PMID:15585952 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP sudan III results in increased expression of NQO1 mRNA CTD PMID:20308224 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein promotes the reaction [sudan III results in increased expression of CYP1A1 mRNA] CTD PMID:22287322 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions		 ISO
EXP		 sudan III results in decreased expression of PPARA protein
sudan III results in decreased expression of PPARA mRNA
[sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased activity of CYP2C11 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased expression of CYP2C11 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP2B2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased activity of CYP3A23-3A1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B1 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP2B2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A2 protein]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 mRNA]; [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in increased expression of CYP3A23-3A1 protein]		 CTD PMID:15585952 PMID:15788368 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO sudan III results in decreased expression of RXRA protein CTD PMID:15585952 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
Sudan IV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Scarlet Red results in increased expression of CYP1A1 mRNA; Scarlet Red results in increased expression of CYP1A1 protein CTD PMID:18418879 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
tolnaftate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli1 GLI family zinc finger 1 multiple interactions ISO Tolnaftate inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA] CTD PMID:20434536 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Tolnaftate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases secretion
decreases expression		 ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein] CTD PMID:11886533 PMID:15284827 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions
decreases expression
decreases secretion		 ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein] CTD PMID:11886533 PMID:15284827 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions ISO Tolnaftate inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA] CTD PMID:20434536 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      chemical role 19420
        donor 18883
          electron donor 3036
            phenolic donor 595
              naphthol + 198
              phloroglucinol + 62
              pyrogallol + 184
              resorcinol + 204
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic aromatic compound 19336
                                  phenols 18605
                                    phenolic donor 595
                                      naphthol + 198
                                      phloroglucinol + 62
                                      pyrogallol + 184
                                      resorcinol + 204
paths to the root