Nrk (Nik related kinase) - Rat Genome Database
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Gene: Nrk (Nik related kinase) Rattus norvegicus
Analyze
Symbol: Nrk
Name: Nik related kinase
RGD ID: 1566163
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including actin cytoskeleton reorganization; activation of JNKK activity; and regulation of spongiotrophoblast cell proliferation. Predicted to localize to cytoplasm. Orthologous to human NRK (Nik related kinase); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC315907; nik-related protein kinase; RGD1566163; similar to Nck-interacting kinase-like embryo specific kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X102,365,747 - 102,462,957 (+)NCBI
Rnor_6.0 EnsemblX109,940,350 - 110,033,085 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X109,940,439 - 110,036,361 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0X110,065,199 - 110,089,124 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X109,798,013 - 109,890,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X109,913,500 - 109,944,079 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X126,448,334 - 126,541,575 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX103,155,670 - 103,249,235 (+)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10801798   PMID:21715335  


Genomics

Comparative Map Data
Nrk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X102,365,747 - 102,462,957 (+)NCBI
Rnor_6.0 EnsemblX109,940,350 - 110,033,085 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X109,940,439 - 110,036,361 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0X110,065,199 - 110,089,124 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X109,798,013 - 109,890,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X109,913,500 - 109,944,079 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X126,448,334 - 126,541,575 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX103,155,670 - 103,249,235 (+)NCBICelera
Cytogenetic MapXq32NCBI
NRK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX105,822,539 - 105,958,610 (+)EnsemblGRCh38hg38GRCh38
GRCh38X105,821,942 - 105,958,610 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X105,066,532 - 105,202,602 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X104,953,192 - 105,089,258 (+)NCBINCBI36hg18NCBI36
Build 34X104,872,680 - 105,008,744NCBI
CeleraX105,541,018 - 105,677,081 (+)NCBI
Cytogenetic MapXq22.3NCBI
HuRefX94,691,867 - 94,829,421 (+)NCBIHuRef
CHM1_1X104,977,838 - 105,113,888 (+)NCBICHM1_1
Nrk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X137,814,980 - 137,911,281 (+)NCBIGRCm39mm39
GRCm39 EnsemblX137,815,179 - 137,911,281 (+)Ensembl
GRCm38X138,914,231 - 139,010,532 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX138,914,430 - 139,010,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X135,448,969 - 135,543,631 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X134,260,869 - 134,354,417 (+)NCBImm8
CeleraX122,184,305 - 122,278,072 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.15NCBI
Nrk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555482,675,645 - 2,797,548 (+)NCBIChiLan1.0ChiLan1.0
NRK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X105,337,040 - 105,473,338 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX105,337,327 - 105,470,331 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X94,957,923 - 95,094,749 (+)NCBIMhudiblu_PPA_v0panPan3
NRK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X79,341,449 - 79,488,046 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX79,341,412 - 79,485,661 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX65,486,392 - 65,633,192 (+)NCBI
ROS_Cfam_1.0X80,973,839 - 81,118,252 (+)NCBI
UMICH_Zoey_3.1X78,456,281 - 78,603,092 (+)NCBI
UNSW_CanFamBas_1.0X80,152,102 - 80,292,152 (+)NCBI
UU_Cfam_GSD_1.0X79,935,837 - 80,082,696 (+)NCBI
Nrk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2X78,909,811 - 79,031,463 (+)NCBI
SpeTri2.0NW_0049364998,629,563 - 8,747,858 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX86,534,483 - 86,663,340 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X86,534,467 - 86,663,340 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X100,896,640 - 101,021,685 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRK
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X93,688,895 - 93,822,776 (+)NCBI
ChlSab1.1 EnsemblX93,689,023 - 93,825,346 (+)Ensembl
Nrk
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480310,719,694 - 10,861,120 (-)NCBI

Position Markers
AV168563  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X110,034,738 - 110,034,817NCBIRnor6.0
Rnor_6.0X110,087,501 - 110,087,580NCBIRnor6.0
Rnor_5.0X109,942,456 - 109,942,535UniSTSRnor5.0
Rnor_5.0X109,892,312 - 109,892,391UniSTSRnor5.0
RGSC_v3.4X126,543,252 - 126,543,331UniSTSRGSC3.4
CeleraX103,250,912 - 103,250,991UniSTS
Cytogenetic MapXq35UniSTS
RH139627  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X110,009,349 - 110,009,550NCBIRnor6.0
Rnor_6.0X110,009,497 - 110,009,550NCBIRnor6.0
Rnor_5.0X109,866,923 - 109,867,124UniSTSRnor5.0
Rnor_5.0X109,867,071 - 109,867,124UniSTSRnor5.0
RGSC_v3.4X126,518,009 - 126,518,062UniSTSRGSC3.4
RGSC_v3.4X126,517,861 - 126,518,062UniSTSRGSC3.4
CeleraX103,225,668 - 103,225,721UniSTS
CeleraX103,225,520 - 103,225,721UniSTS
RH 3.4 Map71128.32UniSTS
Cytogenetic MapXq35UniSTS
px-41g5  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X110,033,253 - 110,033,354NCBIRnor6.0
Rnor_6.0X110,086,016 - 110,086,117NCBIRnor6.0
Rnor_5.0X109,940,971 - 109,941,072UniSTSRnor5.0
Rnor_5.0X109,890,827 - 109,890,928UniSTSRnor5.0
RGSC_v3.4X126,541,767 - 126,541,868UniSTSRGSC3.4
CeleraX103,249,427 - 103,249,528UniSTS
Cytogenetic MapXq35UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X82930791127930791Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X101333032146333032Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX107886746152409805Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:13
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000057049
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 19 6 6 6 2 2 12 26 2
Low 19 24 16 5 16 4 4 49 12 10 5 4
Below cutoff 5 20 12 13 12 2 4 20 8 4 4 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000057049   ⟹   ENSRNOP00000053882
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX109,940,439 - 110,033,061 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093349   ⟹   ENSRNOP00000076290
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX109,996,163 - 110,005,708 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093539   ⟹   ENSRNOP00000076224
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX110,007,214 - 110,012,918 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093542   ⟹   ENSRNOP00000076095
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX110,016,995 - 110,033,085 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093543   ⟹   ENSRNOP00000076291
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX109,940,350 - 109,992,862 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093611   ⟹   ENSRNOP00000076116
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX110,014,252 - 110,016,409 (+)Ensembl
RefSeq Acc Id: NM_001191797   ⟹   NP_001178726
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X102,366,085 - 102,459,657 (+)NCBI
Rnor_6.0X109,940,439 - 110,033,061 (+)NCBI
Rnor_5.0X109,798,013 - 109,890,635 (+)NCBI
CeleraX103,155,670 - 103,249,235 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773418   ⟹   XP_008771640
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X109,995,994 - 110,036,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773463   ⟹   XP_008771685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X110,065,199 - 110,089,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773464   ⟹   XP_008771686
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X110,065,201 - 110,089,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099713   ⟹   XP_038955641
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X102,365,747 - 102,462,957 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178726 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955641 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL88010 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001178726   ⟸   NM_001191797
- UniProtKB: F1LZB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771640   ⟸   XM_008773418
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771685   ⟸   XM_008773463
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008771686   ⟸   XM_008773464
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000053882   ⟸   ENSRNOT00000057049
RefSeq Acc Id: ENSRNOP00000076116   ⟸   ENSRNOT00000093611
RefSeq Acc Id: ENSRNOP00000076095   ⟸   ENSRNOT00000093542
RefSeq Acc Id: ENSRNOP00000076291   ⟸   ENSRNOT00000093543
RefSeq Acc Id: ENSRNOP00000076224   ⟸   ENSRNOT00000093539
RefSeq Acc Id: ENSRNOP00000076290   ⟸   ENSRNOT00000093349
RefSeq Acc Id: XP_038955641   ⟸   XM_039099713
- Peptide Label: isoform X1
Protein Domains
CNH   Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701950
Promoter ID:EPDNEW_R12472
Type:single initiation site
Name:Nrk_1
Description:Nik related kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X109,940,360 - 109,940,420EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566163 AgrOrtholog
Ensembl Genes ENSRNOG00000008880 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000053882 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000076095 UniProtKB/TrEMBL
  ENSRNOP00000076116 UniProtKB/TrEMBL
  ENSRNOP00000076224 UniProtKB/TrEMBL
  ENSRNOP00000076290 UniProtKB/TrEMBL
  ENSRNOP00000076291 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057049 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000093349 UniProtKB/TrEMBL
  ENSRNOT00000093539 UniProtKB/TrEMBL
  ENSRNOT00000093542 UniProtKB/TrEMBL
  ENSRNOT00000093543 UniProtKB/TrEMBL
  ENSRNOT00000093611 UniProtKB/TrEMBL
InterPro Citron UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:315907 UniProtKB/TrEMBL
NCBI Gene 315907 ENTREZGENE
Pfam CNH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Nrk PhenoGen
PROSITE CNH UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART CNH UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A1W2Q617_RAT UniProtKB/TrEMBL
  A0A1W2Q634_RAT UniProtKB/TrEMBL
  A0A1W2Q6E3_RAT UniProtKB/TrEMBL
  A0A1W2Q6I7_RAT UniProtKB/TrEMBL
  A0A1W2Q6J2_RAT UniProtKB/TrEMBL
  F1LZB6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Nrk  Nik related kinase   Nrk_predicted  Nik related kinase (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Nrk_predicted  Nik related kinase (predicted)  RGD1566163_predicted  similar to Nck-interacting kinase-like embryo specific kinase (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1566163_predicted  similar to Nck-interacting kinase-like embryo specific kinase (predicted)  LOC315907  similar to Nck-interacting kinase-like embryo specific kinase  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC315907  similar to Nck-interacting kinase-like embryo specific kinase      Symbol and Name status set to provisional 70820 PROVISIONAL