Kyat1 (kynurenine aminotransferase 1)

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Gene: Kyat1 (kynurenine aminotransferase 1) Rattus norvegicus

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Symbol:

Kyat1

Name:

kynurenine aminotransferase 1

RGD ID:

1306912

Description:

Enables cysteine-S-conjugate beta-lyase activity and glutamine-phenylpyruvate transaminase activity. Involved in L-kynurenine metabolic process and pyruvate metabolic process. Predicted to be located in cytosol and mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human KYAT1 (kynurenine aminotransferase 1); PARTICIPATES IN kynurenine metabolic pathway; selenoamino acid metabolic pathway; tryptophan metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 3,3',5-triiodo-L-thyronine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Ccbl1; cysteine conjugate-beta lyase; cysteine conjugate-beta lyase 1; cysteine conjugate-beta lyase, cytoplasmic; cysteine-S-conjugate beta-lyase; glutamine transaminase K; glutamine--phenylpyruvate transaminase; Gtk; Kat1; KatI; kynurenine aminotransferase I; kynurenine aminotransferase/glutamine transaminase K; kynurenine--oxoglutarate transaminase 1; kynurenine--oxoglutarate transaminase 1, mitochondrial; kynurenine--oxoglutarate transaminase I; LOC311844

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KYAT1 (kynurenine aminotransferase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Kyat1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kyat1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KYAT1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KYAT1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kyat1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KYAT1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KYAT1 (kynurenine aminotransferase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	KYAT1 (kynurenine aminotransferase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Kyat1 (kynurenine aminotransferase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	BNA3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6950	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	kyat1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nkat-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nkat-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	kyat1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	33,857,407 - 33,891,153 (-)	NCBI		GRCr8
mRatBN7.2	3	13,459,598 - 13,493,308 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	13,459,591 - 13,493,355 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	16,532,146 - 16,545,943 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	25,117,112 - 25,130,909 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	23,370,136 - 23,383,952 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	8,752,289 - 8,785,617 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	8,752,625 - 8,766,433 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	14,104,785 - 14,138,554 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	9,195,737 - 9,209,545 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	9,196,036 - 9,209,845 (-)	NCBI
Celera	3	8,233,964 - 8,247,766 (-)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

carcinoma (ISO)

developmental and epileptic encephalopathy (ISO)

dystonia (ISO)

early infantile epileptic encephalopathy (ISO)

Experimental Arthritis (IMP)

Kidney Neoplasms (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

3,3',5-triiodo-L-thyronine (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3H-1,2-dithiole-3-thione (EXP)

4-hydroxyphenyl retinamide (ISO)

4-methylthio-2-oxobutanoic acid (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

Aroclor 1254 (EXP)

avobenzone (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

buspirone (EXP)

cannabidiol (ISO)

carbaryl (EXP)

carbon nanotube (ISO)

cisplatin (EXP,ISO)

cobalt dichloride (ISO)

colforsin daropate hydrochloride (ISO)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (ISO)

cypermethrin (ISO)

Dibutyl phosphate (ISO)

dimethoate (EXP)

epoxiconazole (ISO)

ethanol (EXP)

felbamate (EXP)

fenvalerate (ISO)

flutamide (EXP)

gabapentin (EXP)

gentamycin (EXP)

glafenine (EXP)

Hexachloro-1,3-butadiene (EXP)

indometacin (EXP)

inulin (ISO)

L-cystathionine (ISO)

L-cysteine (EXP,ISO)

L-cystine (ISO)

L-methionine (ISO)

lamotrigine (EXP)

lanthionine (ISO)

leflunomide (EXP)

mercury dichloride (EXP,ISO)

methomyl (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

N-methyl-4-phenylpyridinium (ISO)

nefazodone (EXP)

nimesulide (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (EXP,ISO)

phenytoin (EXP)

pirinixic acid (ISO)

potassium dichromate (EXP)

pregnenolone 16alpha-carbonitrile (EXP)

quinolin-8-ol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thioacetamide (EXP)

thyroxine (EXP)

tiagabine (EXP)

titanium dioxide (ISO)

triphenyl phosphate (EXP)

Triptolide (ISO)

triptonide (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vigabatrin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biosynthetic process (IEA)

kynurenine metabolic process (IEA,ISO,ISS)

L-kynurenine catabolic process (IEA)

L-kynurenine metabolic process (IDA)

pyruvate metabolic process (IDA)

response to bacterium (IEA,ISO)

Cellular Component

cytoplasm (IBA)

cytosol (IEA)

mitochondrial matrix (IEA)

mitochondrion (IBA,ISO)

Molecular Function

cysteine-S-conjugate beta-lyase activity (IDA,IEA,ISO)

glutamine-phenylpyruvate transaminase activity (IDA)

kynurenine-oxoglutarate transaminase activity (IBA,IEA,ISO,ISS)

protein binding (ISO)

protein homodimerization activity (IEA,ISO)

pyridoxal phosphate binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

kynurenine metabolic pathway (ISO)

selenoamino acid metabolic pathway (IEA)

tryptophan metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.	Abraham DG and Cooper AJ, Anal Biochem. 1991 Sep 2;197(2):421-7.
2.	Intraarticular interferon-beta gene therapy ameliorates adjuvant arthritis in rats.	Adriaansen J, etal., Hum Gene Ther. 2006 Oct;17(10):985-96.
3.	Normalization and subtraction: two approaches to facilitate gene discovery.	Bonaldo MF, etal., Genome Res 1996 Sep;6(9):791-806.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Structure, expression, and function of kynurenine aminotransferases in human and rodent brains.	Han Q, etal., Cell Mol Life Sci. 2010 Feb;67(3):353-68. doi: 10.1007/s00018-009-0166-4. Epub 2009 Oct 15.
7.	Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain.	Malherbe P, etal., FEBS Lett. 1995 Jun 26;367(2):141-4.
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7883047	PMID:7926014	PMID:8294935	PMID:8502223	PMID:8914928	PMID:12850267	PMID:15364907	PMID:15880762	PMID:16258845	PMID:19338303	PMID:23012479	PMID:34800366

Genomics

Comparative Map Data

Kyat1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	33,857,407 - 33,891,153 (-)	NCBI		GRCr8
mRatBN7.2	3	13,459,598 - 13,493,308 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	13,459,591 - 13,493,355 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	16,532,146 - 16,545,943 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	25,117,112 - 25,130,909 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	23,370,136 - 23,383,952 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	8,752,289 - 8,785,617 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	8,752,625 - 8,766,433 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	14,104,785 - 14,138,554 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	9,195,737 - 9,209,545 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	9,196,036 - 9,209,845 (-)	NCBI
Celera	3	8,233,964 - 8,247,766 (-)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

KYAT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	128,832,942 - 128,882,523 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	128,832,942 - 128,882,494 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	9	128,819,663 - 128,881,931 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	131,595,221 - 131,644,802 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	130,635,213 - 130,684,175 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	128,674,776 - 128,723,886	NCBI
Celera	9	102,246,153 - 102,296,248 (-)	NCBI		Celera
Cytogenetic Map	9	q34.11	NCBI
HuRef	9	101,204,381 - 101,252,461 (-)	NCBI		HuRef
CHM1_1	9	131,746,397 - 131,795,334 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	141,037,719 - 141,087,270 (-)	NCBI		T2T-CHM13v2.0

Kyat1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	30,075,136 - 30,096,307 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	30,075,136 - 30,095,859 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	30,185,124 - 30,206,295 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	30,185,124 - 30,205,847 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	30,040,651 - 30,061,219 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	30,007,140 - 30,027,708 (-)	NCBI		MGSCv36	mm8
Celera	2	29,889,003 - 29,909,565 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	21.31	NCBI

Kyat1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955570	1,211,160 - 1,254,303 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955570	1,211,950 - 1,260,561 (-)	NCBI	ChiLan1.0	ChiLan1.0

KYAT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	10,470,023 - 10,518,141 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	10,472,372 - 10,520,490 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	99,956,240 - 100,004,366 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	128,623,475 - 128,670,061 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	128,623,946 - 128,637,844 (-)	Ensembl	panpan1.1		panPan2

KYAT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	54,760,212 - 54,796,996 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	54,760,276 - 54,796,848 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	53,955,737 - 53,992,502 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	55,681,245 - 55,718,029 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	55,681,260 - 55,718,026 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	54,442,358 - 54,478,686 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	54,754,709 - 54,791,457 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	54,848,260 - 54,884,843 (+)	NCBI		UU_Cfam_GSD_1.0

Kyat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	196,530,527 - 196,575,811 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	16,297,991 - 16,344,745 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	16,299,054 - 16,344,587 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KYAT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	269,172,628 - 269,209,478 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	269,172,628 - 269,209,553 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	303,188,686 - 303,225,635 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KYAT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	9,271,016 - 9,311,984 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666096	165,054 - 207,022 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Kyat1
237 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	290
Count of miRNA genes:	184
Interacting mature miRNAs:	204
Transcripts:	ENSRNOT00000021865
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat

Markers in Region

D3Wox39

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	13,482,810 - 13,482,958 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	8,775,139 - 8,775,286	NCBI	Rnor6.0
Rnor_5.0	3	14,128,089 - 14,128,236	UniSTS	Rnor5.0
RGSC_v3.4	3	9,218,045 - 9,218,192	UniSTS	RGSC3.4
Celera	3	8,249,443 - 8,249,590	UniSTS
Cytogenetic Map	3	p12	UniSTS

BM386769

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	13,491,261 - 13,491,481 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	8,783,594 - 8,783,813	NCBI	Rnor6.0
Rnor_5.0	3	14,136,544 - 14,136,763	UniSTS	Rnor5.0
RGSC_v3.4	3	9,261,367 - 9,261,586	UniSTS	RGSC3.4
Celera	3	8,257,899 - 8,258,118	UniSTS
RH 3.4 Map	3	51.61	UniSTS
Cytogenetic Map	3	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF100154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF267749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF267752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S61960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021865 ⟹ ENSRNOP00000021865

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	13,459,591 - 13,492,741 (-)	Ensembl
Rnor_6.0 Ensembl	3	8,752,625 - 8,766,433 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095192 ⟹ ENSRNOP00000091831

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	13,459,591 - 13,493,355 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100797 ⟹ ENSRNOP00000081492

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	13,459,591 - 13,492,741 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102626 ⟹ ENSRNOP00000085700

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	13,459,701 - 13,492,951 (-)	Ensembl

RefSeq Acc Id:

NM_001013164 ⟹ NP_001013182

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,743 - 33,871,551 (-)	NCBI
mRatBN7.2	3	13,459,927 - 13,473,735 (-)	NCBI
Rnor_6.0	3	8,752,625 - 8,766,433 (-)	NCBI
Rnor_5.0	3	14,104,785 - 14,138,554 (-)	NCBI
RGSC_v3.4	3	9,195,737 - 9,209,545 (-)	RGD
Celera	3	8,233,964 - 8,247,766 (-)	RGD

Sequence:

show sequence

ATGTTCAGGAGTGCAGCAGCCCTCTCGGTGCACCTGATGTGGCCACTCTGGGGAAGGAAAGCTG
GAGCCTCACTCACCCGGTGCTTGCACCAGTCTCTCACCATGACCAAACGGCTGCAGGCTCGGAG
GCTGGACGGGATTGATCAAAACCTCTGGGTGGAGTTTGGCAAACTGACCAAGGAGTATGACGTC
GTGAACTTGGGTCAGGGCTTCCCTGACTTCTCGCCTCCGGACTTTGCAACGCAAGCTTTTCAGC
AGGCTACCAGTGGGAACTTCATGCTCAACCAGTACACCAGGGCATTTGGTTACCCACCACTGAC
AAACGTCCTGGCAAGTTTCTTTGGCAAGCTGCTGGGACAGGAGATGGACCCACTCACGAATGTG
CTGGTGACAGTGGGTGCCTATGGGGCCTTGTTCACAGCCTTTCAGGCCCTGGTGGATGAAGGAG
ATGAGGTCATCATCATGGAACCTGCTTTTGACTGTTATGAACCCATGACAATGATGGCTGGAGG
TTGCCCTGTGTTCGTGACTCTGAAGCCGAGCCCTGCTCCTAAGGGGAAACTGGGAGCCAGCAAT
GATTGGCAACTGGATCCTGCAGAACTGGCCAGCAAGTTCACACCTCGCACCAAGATCCTGGTCC
TCAACACACCCAACAACCCTTTAGGAAAGGTATTCTCTAGGATGGAGCTGGAGCTGGTGGCTAA
TCTGTGCCAGCAGCACGATGTCGTGTGCATCTCTGATGAGGTCTACCAGTGGCTGGTCTATGAC
GGGCACCAGCACGTCAGCATCGCCAGCCTCCCTGGCATGTGGGATCGGACCCTGACCATCGGCA
GTGCAGGCAAAAGCTTCAGTGCCACTGGCTGGAAGGTGGGCTGGGTCATGGGTCCAGATAACAT
CATGAAGCACCTGAGGACAGTGCACCAGAATTCTATCTTCCACTGCCCCACCCAGGCCCAGGCT
GCAGTAGCCCAGTGCTTTGAGCGGGAGCAGCAACACTTTGGACAACCCAGCAGCTACTTTTTGC
AGCTGCCACAGGCCATGGAGCTGAACCGAGACCACATGATCCGTAGCCTGCAGTCAGTGGGCCT
CAAGCTCTGGATCTCCCAGGGGAGCTACTTCCTCATTGCAGACATCTCAGACTTCAAGAGCAAG
ATGCCTGACCTGCCCGGAGCTGAGGATGAGCCTTATGACAGACGCTTTGCCAAGTGGATGATCA
AAAACATGGGCTTGGTGGGCATCCCTGTCTCCACATTCTTCAGTCGGCCCCATCAGAAGGACTT
TGACCACTACATCCGATTCTGTTTTGTCAAGGACAAGGCCACACTCCAGGCCATGGATGAGAGA
CTGCGCAAGTGGAAAGAGCTCCAACCCTGAGGAGGCTGCCCTCAGCCCCACCTCGAACACAGGC
CTCAGCTAT

hide sequence

RefSeq Acc Id:

XM_006233811 ⟹ XP_006233873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,891,108 (-)	NCBI
mRatBN7.2	3	13,459,598 - 13,493,302 (-)	NCBI
Rnor_6.0	3	8,752,289 - 8,785,607 (-)	NCBI
Rnor_5.0	3	14,104,785 - 14,138,554 (-)	NCBI

Sequence:

show sequence

GAGCTGTCCAGAGAACGCCAGGGTGGAACCTCTGGGTAGGGGGCGAGTGCGCGGAGGAGCGCGG
ATCTGCCAGGACAAGTGCAGCCTGGGGACCGTGGCGGAAACTCAAGTGAAAGGCACGCACGGAA
GCCGGGCGCGCGTGATTGGGTTCAGTGAGGTGACAGCGCGCGTCCCTTTTTATACTCGACCCAC
TCAACAAGGCCCGCCGCTCTCGGCCGCCACGCAGGCAGCCCTAGTCCTGTTTCTGGCTACCCAC
AGCCAGTCGCGCCGTGGGTCTTTGGCGCCTTGTTTTGTCTGTCACGGTACCGCTTCTTAGGTCT
CCGCCCCGGAAGTGATATCACCGAGCGCAAACCCGGGGGTCCCTAAGGCTGCCCCCCCCCCCCC
CCGGCGTCTTTAAAGGGAACTCGCAGCTTTGCACTGACAGTGCTCTTGAGCCAAGTTGCTTCTG
GGCGGAAGTAGTCCATCTAGGGCTCGGCCTCTTTAAAGAAACAGACTTCTGCAACCTTGGGACT
ACGTTTGGGGTCGCCGGCTATTGGACGGAGCAGCGCAATTGTTAGCTGAAGCAGCTCACCATGA
CCAAACGGCTGCAGGCTCGGAGGCTGGACGGGATTGATCAAAACCTCTGGGTGGAGTTTGGCAA
ACTGACCAAGGAGTATGACGTCGTGAACTTGGGTCAGGGCTTCCCTGACTTCTCGCCTCCGGAC
TTTGCAACGCAAGCTTTTCAGCAGGCTACCAGTGGGAACTTCATGCTCAACCAGTACACCAGGG
CATTTGGTTACCCACCACTGACAAACGTCCTGGCAAGTTTCTTTGGCAAGCTGCTGGGACAGGA
GATGGACCCACTCACGAATGTGCTGGTGACAGTGGGTGCCTATGGGGCCTTGTTCACAGCCTTT
CAGGCCCTGGTGGATGAAGGAGATGAGGTCATCATCATGGAACCTGCTTTTGACTGTTATGAAC
CCATGACAATGATGGCTGGAGGTTGCCCTGTGTTCGTGACTCTGAAGCCGAGCCCTGCTCCTAA
GGGGAAACTGGGAGCCAGCAATGATTGGCAACTGGATCCTGCAGAACTGGCCAGCAAGTTCACA
CCTCGCACCAAGATCCTGGTCCTCAACACACCCAACAACCCTTTAGGAAAGGTATTCTCTAGGA
TGGAGCTGGAGCTGGTGGCTAATCTGTGCCAGCAGCACGATGTCTTGTGCATCTCTGATGAGGT
CTACCAGTGGCTGGTCTATGACGGGCACCAGCACGTCAGCATCGCCAGCCTCCCTGGCATGTGG
GATCGGACCCTGACCATCGGCAGTGCAGGCAAAAGCTTCAGTGCCACTGGCTGGAAGGTGGGCT
GGGTCATGGGTCCAGATAACATCATGAAGCACCTGAGGACAGTGCACCAGAATTCTATCTTCCA
CTGCCCCACCCAGGCCCAGGCTGCAGTAGCCCAGTGCTTTGAGCGGGAGCAGCAACACTTTGGA
CAACCCAGCAGCTACTTTTTGCAGCTGCCACAGGCCATGGAGCTGAACCGAGACCACATGATCC
GTAGCCTGCAGTCAGTGGGCCTCAAGCTCTGGATCTCCCAGGGGAGCTACTTCCTCATTGCAGA
CATCTCAGACTTCAAGAGCAAGATGCCTGACCTGCCCGGAGCTGAGGATGAGCCTTATGACAGA
CGCTTTGCCAAGTGGATGATCAAAAACATGGGCTTGGTGGGCATCCCTGTCTCCACATTCTTCA
GTCGGCCCCATCAGAAGGACTTTGACCACTACATCCGATTCTGTTTTGTCAAGGACAAGGCCAC
ACTCCAGGCCATGGATGAGAGACTGCGCAAGTGGAAAGAGCTCCAACCCTGAGGAGGCTGCCCT
CAGCCCCACCTCGAACACAGGCCTCAGCTATGCCTTAGCACAGGGATGGCACTGGAGGGCCCAG
CTGTGTGACTGCGCATGTTTCCAGAAAAGAGGCCATGTCTTGGGGGTTGAAGCCATCCTTTCCC
AGTGTCCATCTGGACTATTGGGTTGGGGGCCAGTTCTGGGTCTCAGCCTACTCCTCTGTAGGTT
GCCTGTAGGGTTTTGATTGTTTCTGGCCTCTCTGCCTGGGGCAGGAAAGGGTGGAATATCAGGC
CCGGTACCACCTTAGCCCTGCCGAGGCTCTGTGGCTTCTCTACATCTTCTCCTGTGACCTCAGG
ATGTTGCTACTGTTCCTAATAAAGTTTTAAGTTATTAGGACCCTCAA

hide sequence

RefSeq Acc Id:

XM_008761658 ⟹ XP_008759880

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,891,153 (-)	NCBI
mRatBN7.2	3	13,459,598 - 13,493,305 (-)	NCBI
Rnor_6.0	3	8,752,289 - 8,785,611 (-)	NCBI

Sequence:

show sequence

CGGGGAGCTGTCCAGAGAACGCCAGGGTGGAACCTCTGGGTAGGGGGCGAGTGCGCGGAGGAGC
GCGGATCTGCCAGGACAAGTGCAGCCTGGGGACCGTGGCGGAAACTCAAGTGAAAGGCACGCAC
GGAAGCCGGGCGCGCGTGATTGGGTTCAGTGAGGTGACAGCGCGCGTCCCTTTTTATACTCGAC
CCACTCAACAAGGCCCGCCGCTCTCGGCCGCCACGCAGGCAGCCCTAGTCCTGTTTCTGGCTAC
CCACAGCCAGTCGCGCCGTGGGTCTTTGGCGCCTTGTTTTGTCTGTCACGGTACCGCTTCTTAG
GTCTCCGCCCCGGAAGTGATATCACCGAGCGCAAACCCGGGGGTCCCTAAGGCTGCCCCCCCCC
CCCCCCGGCGTCTTTAAAGGGAACTCGCAGCTTTGCACTGACAGTGCTCTTGAGCCAAGTTGCT
TCTGGGCGGAAGTAGTCCATCTAGGGCTCGGCCTCTTTAAAGAAACAGACTTCTGCAACCTTGG
GACTACGTTTGGGGTCGCCGGCTATTGGACGGAGCAGCGCAATTGTTAGCTGAAGCAGAACTGT
GTGTGGGACTCAGGCCCTGGCTTGGAGCCATTTTCTGGGCTAGGCTGTCTGCCCTTCTGTCCCT
CTGGAGGGGAAGCCTGCAGTGCCTGTGGACCTACCTCAGAGGCATGTTCAGGAGTGCAGCAGCC
CTCTCGGTGCACCTGATGTGGCCACTCTGGGGAAGGAAAGCTGGAGCCTCACTCACCCGGTGCT
TGCACCAGTCTCTCACCATGACCAAACGGCTGCAGGCTCGGAGGCTGGACGGGATTGATCAAAA
CCTCTGGGTGGAGTTTGGCAAACTGACCAAGGAGTATGACGTCGTGAACTTGGGTCAGGGCTTC
CCTGACTTCTCGCCTCCGGACTTTGCAACGCAAGCTTTTCAGCAGGCTACCAGTGGGAACTTCA
TGCTCAACCAGTACACCAGGGCATTTGGTTACCCACCACTGACAAACGTCCTGGCAAGTTTCTT
TGGCAAGCTGCTGGGACAGGAGATGGACCCACTCACGAATGTGCTGGTGACAGTGGGTGCCTAT
GGGGCCTTGTTCACAGCCTTTCAGGCCCTGGTGGATGAAGGAGATGAGGTCATCATCATGGAAC
CTGCTTTTGACTGTTATGAACCCATGACAATGATGGCTGGAGGTTGCCCTGTGTTCGTGACTCT
GAAGCCGAGCCCTGCTCCTAAGGGGAAACTGGGAGCCAGCAATGATTGGCAACTGGATCCTGCA
GAACTGGCCAGCAAGTTCACACCTCGCACCAAGATCCTGGTCCTCAACACACCCAACAACCCTT
TAGGAAAGGTATTCTCTAGGATGGAGCTGGAGCTGGTGGCTAATCTGTGCCAGCAGCACGATGT
CTTGTGCATCTCTGATGAGGTCTACCAGTGGCTGGTCTATGACGGGCACCAGCACGTCAGCATC
GCCAGCCTCCCTGGCATGTGGGATCGGACCCTGACCATCGGCAGTGCAGGCAAAAGCTTCAGTG
CCACTGGCTGGAAGGTGGGCTGGGTCATGGGTCCAGATAACATCATGAAGCACCTGAGGACAGT
GCACCAGAATTCTATCTTCCACTGCCCCACCCAGGCCCAGGCTGCAGTAGCCCAGTGCTTTGAG
CGGGAGCAGCAACACTTTGGACAACCCAGCAGCTACTTTTTGCAGCTGCCACAGGCCATGGAGC
TGAACCGAGACCACATGATCCGTAGCCTGCAGTCAGTGGGCCTCAAGCTCTGGATCTCCCAGGG
GAGCTACTTCCTCATTGCAGACATCTCAGACTTCAAGAGCAAGATGCCTGACCTGCCCGGAGCT
GAGGATGAGCCTTATGACAGACGCTTTGCCAAGTGGATGATCAAAAACATGGGCTTGGTGGGCA
TCCCTGTCTCCACATTCTTCAGTCGGCCCCATCAGAAGGACTTTGACCACTACATCCGATTCTG
TTTTGTCAAGGACAAGGCCACACTCCAGGCCATGGATGAGAGACTGCGCAAGTGGAAAGAGCTC
CAACCCTGAGGAGGCTGCCCTCAGCCCCACCTCGAACACAGGCCTCAGCTATGCCTTAGCACAG
GGATGGCACTGGAGGGCCCAGCTGTGTGACTGCGCATGTTTCCAGAAAAGAGGCCATGTCTTGG
GGGTTGAAGCCATCCTTTCCCAGTGTCCATCTGGACTATTGGGTTGGGGGCCAGTTCTGGGTCT
CAGCCTACTCCTCTGTAGGTTGCCTGTAGGGTTTTGATTGTTTCTGGCCTCTCTGCCTGGGGCA
GGAAAGGGTGGAATATCAGGCCCGGTACCACCTTAGCCCTGCCGAGGCTCTGTGGCTTCTCTAC
ATCTTCTCCTGTGACCTCAGGATGTTGCTACTGTTCCTAATAAAGTTTTAAGTTATTAGGACCC
TCAA

hide sequence

RefSeq Acc Id:

XM_008761659 ⟹ XP_008759881

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,891,124 (-)	NCBI
mRatBN7.2	3	13,459,701 - 13,492,951 (-)	NCBI
Rnor_6.0	3	8,752,723 - 8,785,617 (-)	NCBI

Sequence:

show sequence

GCGCGCCGGGGAGCTGTCCAGAGAACGCCAGGGTGGAACCTCTGGGTAGGGGGCGAGTGCGCGG
AGGAGCGCGGATCTGCCAGGACAAGTGCAGCCTGGGGACCGTGGCGGAAACTCAAGTGAAAGGC
ACGCACGGAAGCCGGGCGCGCGTGATTGGGTTCAGTGAGGTGACAGCGCGCGTCCCTTTTTATA
CTCGACCCACTCAACAAGGCCCGCCGCTCTCGGCCGCCACGCAGGCAGCCCTAGTCCTGTTTCT
GGCTACCCACAGCCAGTCGCGCCGTGGGTCTTTGGCGCCTTGTTTTGTCTGTCACGGTACCGCT
TCTTAGGTCTCCGCCCCGGAAGTGATATCACCGAGCGCAAACCCGGGGGTCCCTAAGGCTGCCC
CCCCCCCCCCCCGGCGTCTTTAAAGGGAACTCGCAGCTTTGCACTGACAGTGCTCTTGAGCCAA
GTTGCTTCTGGGCGGAAGTAGTCCATCTAGGGCTCGGCCTCTTTAAAGAAACAGACTTCTGCAA
CCTTGGGACTACGTTTGGGGTCGCCGGCTATTGGACGGAGCAGCGCAATTGTTAGCTGAAGCAG
AACTGTGTGTGGGACTCAGGCCCTGGCTTGGAGCCATTTTCTGGGCTAGGCTGTCTGCCCTTCT
GTCCCTCTGGAGGGGAAGCCTGCAGTGCCTGTGGACCTACCTCAGAGGCATGTTCAGGAGTGCA
GCAGCCCTCTCGGTGCACCTGATGTGGCCACTCTGGGGAAGGAAAGCTGGAGCCTCACTCACCC
GGTGCTTGCACCAGTCTCTCACCATGACCAAACGGCTGCAGGCTCGGAGGCTGGACGGGATTGA
TCAAAACCTCTGGGTGGAGTTTGGCAAACTGACCAAGGAGTATGACGTCGTGAACTTGGGTCAG
GGCTTCCCTGACTTCTCGCCTCCGGACTTTGCAACGCAAGCTTTTCAGCAGGCTACCAGTGGGA
ACTTCATGCTCAACCAGTACACCAGGGCATTTGGTTACCCACCACTGACAAACGTCCTGGCAAG
TTTCTTTGGCAAGCTGCTGGGACAGGAGATGGACCCACTCACGAATGTGCTGGTGACAGTGGGT
GCCTATGGGGCCTTGTTCACAGCCTTTCAGGCCCTGGTGGATGAAGGAGATGAGGTCATCATCA
TGGAACCTGCTTTTGACTGTTATGAACCCATGACAATGATGGCTGGAGGTTGCCCTGTGTTCGT
GACTCTGAAGCCGAGCCCTGCTCCTAAGGGGAAACTGGGAGCCAGCAATGATTGGCAACTGGAT
CCTGCAGAACTGGCCAGCAAGTTCACACCTCGCACCAAGATCCTGGTCCTCAACACACCCAACA
ACCCTTTAGGAAAGGTATTCTCTAGGATGGAGCTGGAGCTGGTGGCTAATCTGTGCCAGCAGCA
CGATGTCTTGTGCATCTCTGATGAGGTCTACCAGTGGCTGGTCTATGACGGGCACCAGCACGTC
AGCATCGCCAGCCTCCCTGGCATGTGGGATCGGACCCTGACCATCGGCAGTGCAGGCAAAAGCT
TCAGTGCCACTGGCTGGAAGGTGGGCTGGGTCATGGGTCCAGATAACATCATGAAGCACCTGAG
GACAGTGCACCAGAATTCTATCTTCCACTGCCCCACCCAGGCCCAGGCTGCAGTAGCCCAGTGC
TTTGAGCGGGAGCAGCAACACTTTGGACAACCCAGCAGCTACTTTTTGCAGCTGCCACAGGCCA
TGGAGCTGAACCGAGACCACATGATCCGTAGCCTGCAGTCAGTGGGCCTCAAGCTCTGGATCTC
CCAGGGGAGCTACTTCCTCATTGCAGACATCTCAGACTTCAAGAGCAAGATGCCTGACCTGCCC
GGAGCTGAGGATGAGCCTTATGACAGACGCTTTGCCAAGTGGATGATCAAAAACATGGTGAGAG
AAAGCTGGGAGAAGGCCGCTGGGCCTGGATAGCCACTGGTTGGGGCAAGAGAAGACTCGGTGTA
TATCTTGCAGGACAAGGC

hide sequence

RefSeq Acc Id:

XM_039105230 ⟹ XP_038961158

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,888,420 (-)	NCBI
mRatBN7.2	3	13,459,598 - 13,490,473 (-)	NCBI

RefSeq Acc Id:

XM_039105231 ⟹ XP_038961159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,891,108 (-)	NCBI
mRatBN7.2	3	13,459,598 - 13,493,305 (-)	NCBI

RefSeq Acc Id:

XM_039105232 ⟹ XP_038961160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	33,857,407 - 33,891,108 (-)	NCBI
mRatBN7.2	3	13,459,598 - 13,493,308 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013182	(Get FASTA)	NCBI Sequence Viewer
	XP_006233873	(Get FASTA)	NCBI Sequence Viewer
	XP_008759880	(Get FASTA)	NCBI Sequence Viewer
	XP_008759881	(Get FASTA)	NCBI Sequence Viewer
	XP_038961158	(Get FASTA)	NCBI Sequence Viewer
	XP_038961159	(Get FASTA)	NCBI Sequence Viewer
	XP_038961160	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB26845	(Get FASTA)	NCBI Sequence Viewer
	AAF06837	(Get FASTA)	NCBI Sequence Viewer
	EDL93335	(Get FASTA)	NCBI Sequence Viewer
	EDL93336	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021865.4
	ENSRNOP00000081492.1
	ENSRNOP00000085700.1
	ENSRNOP00000091831.1
GenBank Protein	Q08415	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013182 ⟸ NM_001013164

- UniProtKB:

Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MFRSAAALSVHLMWPLWGRKAGASLTRCLHQSLTMTKRLQARRLDGIDQNLWVEFGKLTKEYDV
VNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFFGKLLGQEMDPLTNV
LVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPVFVTLKPSPAPKGKLGASN
DWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVANLCQQHDVVCISDEVYQWLVYD
GHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQA
AVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHMIRSLQSVGLKLWISQGSYFLIADISDFKSK
MPDLPGAEDEPYDRRFAKWMIKNMGLVGIPVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDER
LRKWKELQP

hide sequence

RefSeq Acc Id:	XP_006233873 ⟸ XM_006233811
- Peptide Label:	isoform X3
- UniProtKB:	Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MTKRLQARRLDGIDQNLWVEFGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYT RAFGYPPLTNVLASFFGKLLGQEMDPLTNVLVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCY EPMTMMAGGCPVFVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKILVLNTPNNPLGKVFS RMELELVANLCQQHDVLCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKV GWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHM IRSLQSVGLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGIPVSTF FSRPHQKDFDHYIRFCFVKDKATLQAMDERLRKWKELQP hide sequence

RefSeq Acc Id:	XP_008759880 ⟸ XM_008761658
- Peptide Label:	isoform X1
- UniProtKB:	Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot), A6JTW0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFRSAAALSVHLMWPLWGRKAGASLTRCLHQSLTMTKRLQARRLDGIDQNLWVEFGKLTKEYDV VNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFFGKLLGQEMDPLTNV LVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPVFVTLKPSPAPKGKLGASN DWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVANLCQQHDVLCISDEVYQWLVYD GHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQA AVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHMIRSLQSVGLKLWISQGSYFLIADISDFKSK MPDLPGAEDEPYDRRFAKWMIKNMGLVGIPVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDER LRKWKELQP hide sequence

RefSeq Acc Id:	XP_008759881 ⟸ XM_008761659
- Peptide Label:	isoform X4
- UniProtKB:	Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot), A0A8I5ZZT5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFRSAAALSVHLMWPLWGRKAGASLTRCLHQSLTMTKRLQARRLDGIDQNLWVEFGKLTKEYDV VNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFFGKLLGQEMDPLTNV LVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPVFVTLKPSPAPKGKLGASN DWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVANLCQQHDVLCISDEVYQWLVYD GHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQA AVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHMIRSLQSVGLKLWISQGSYFLIADISDFKSK MPDLPGAEDEPYDRRFAKWMIKNMVRESWEKAAGPG hide sequence

Ensembl Acc Id:

ENSRNOP00000021865 ⟸ ENSRNOT00000021865

RefSeq Acc Id:	XP_038961160 ⟸ XM_039105232
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I5ZSP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961159 ⟸ XM_039105231
- Peptide Label:	isoform X2
- UniProtKB:	Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot), A0A8I6AEE2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961158 ⟸ XM_039105230
- Peptide Label:	isoform X1
- UniProtKB:	Q9R096 (UniProtKB/Swiss-Prot), Q08415 (UniProtKB/Swiss-Prot), A6JTW0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085700 ⟸ ENSRNOT00000102626

Ensembl Acc Id:

ENSRNOP00000091831 ⟸ ENSRNOT00000095192

Ensembl Acc Id:

ENSRNOP00000081492 ⟸ ENSRNOT00000100797

Protein Domains

Aminotransferase class I/classII

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q08415-F1-model_v2	AlphaFold	Q08415	1-423	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306912	AgrOrtholog
BioCyc Gene	G2FUF-50229	BioCyc
Ensembl Genes	ENSRNOG00000016097	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021865.7	UniProtKB/TrEMBL
	ENSRNOT00000095192.1	UniProtKB/TrEMBL
	ENSRNOT00000100797.1	UniProtKB/TrEMBL
	ENSRNOT00000102626.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.640.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.90.1150.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Aminotransferase_I/II	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kynurenine-oxoglutarate_AT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_dom1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_major	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:311844	UniProtKB/Swiss-Prot
NCBI Gene	311844	ENTREZGENE
PANTHER	FI04487P	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR43807:SF14	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Aminotran_1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Kyat1	PhenoGen
RatGTEx	ENSRNOG00000016097	RatGTEx
Superfamily-SCOP	SSF53383	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZSP9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZZT5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AEE2	ENTREZGENE, UniProtKB/TrEMBL
	A6JTW0	ENTREZGENE, UniProtKB/TrEMBL
	G3V827_RAT	UniProtKB/TrEMBL
	KAT1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9R096	ENTREZGENE
UniProt Secondary	Q9R096	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-04	Kyat1	kynurenine aminotransferase 1	Ccbl1	cysteine conjugate-beta lyase, cytoplasmic	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-18	Ccbl1	cysteine conjugate-beta lyase, cytoplasmic	Ccbl1	cysteine conjugate-beta lyase 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Ccbl1	cysteine conjugate-beta lyase	Ccbl1_predicted	cysteine conjugate-beta lyase (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ccbl1_predicted	cysteine conjugate-beta lyase (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)