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Gene: Mtnr1b (melatonin receptor 1B) Rattus norvegicus
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Symbol: Mtnr1b
Name: melatonin receptor 1B
Description: Predicted to have G protein-coupled receptor activity. Involved in several processes, including negative regulation of cGMP-mediated signaling; negative regulation of transport; and regulation of transmission of nerve impulse. Predicted to localize to plasma membrane. Used to study acute pancreatitis. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B); INTERACTS WITH ammonium chloride; flavonoids; graphite.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: mel-1B-R; mel1b melatonin receptor; mel1b receptor; Mel1b-r; melatonin receptor type 1B; Mt2
Orthologs:
Homo sapiens (human) : MTNR1B (melatonin receptor 1B)  HGNC  Alliance
Mus musculus (house mouse) : Mtnr1b (melatonin receptor 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtnr1b (melatonin receptor 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : MTNR1B (melatonin receptor 1B)
Canis lupus familiaris (dog) : MTNR1B (melatonin receptor 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtnr1b (melatonin receptor 1B)
Sus scrofa (pig) : MTNR1B (melatonin receptor 1B)
Chlorocebus sabaeus (African green monkey) : MTNR1B (melatonin receptor 1B)
Heterocephalus glaber (naked mole-rat) : Mtnr1b (melatonin receptor 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0814,359,270 - 14,373,894 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl814,359,270 - 14,373,894 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0814,446,990 - 14,461,614 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4812,625,154 - 12,639,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1812,628,288 - 12,628,810 (-)NCBI
Celera814,104,164 - 14,118,680 (-)NCBICelera
Cytogenetic Map8q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mtnr1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620798
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.