hepatitis B - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

RGD DISEASE ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	hepatitis B	go back to main search page
Accession:	DOID:2043	browse the term
Definition:	A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice. (DO)
Synonyms:	exact_synonym:	hepatitis B infection; hepatitis B virus infection
	related_synonym:	HBV, resistance to; HBV, susceptibility to; hepatitis B virus, resistance to; hepatitis B virus, susceptibility to; serum hepatitis
	primary_id:	MESH:D006509
	alt_id:	OMIM:610424
	xref:	EFO:0004197; NCI:C3097
For additional species annotation, visit the Alliance of Genome Resources.

Please select species to view GViewer data.

show annotations for term's descendants Sort by:
Rat (126) Mouse (128) Human (150) Chinchilla (91) Bonobo (105) Dog (122) Squirrel (91) Pig (119) Green Monkey (100) Naked Mole-rat (92) All
Genes (1114) Variants (10)

hepatitis B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

N

activation induced cytidine deaminase

treatment

NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634

G

G

activation induced cytidine deaminase

treatment

NCBI chr11:8,426,920...8,438,331
Ensembl chr11:8,428,922...8,431,641

G

P

activation induced cytidine deaminase

treatment

NCBI chr 5:62,777,236...62,787,342
Ensembl chr 5:62,777,352...62,787,369

G

S

activation induced cytidine deaminase

treatment

NCBI chrNW_004936870:25,039...34,601
Ensembl chrNW_004936870:25,039...34,601

G

D

activation induced cytidine deaminase

treatment

NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789

G

B

activation induced cytidine deaminase

treatment

NCBI chr12:8,688,392...8,699,008
Ensembl chr12:8,904,273...8,913,917

G

R

activation-induced cytidine deaminase

treatment

RGD

NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972

G

M

activation-induced cytidine deaminase

treatment

RGD

NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139

G

H

activation induced cytidine deaminase

treatment

RGD

NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242

G

N

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chrNW_004624868:5,110,602...5,131,167
Ensembl chrNW_004624868:5,109,846...5,116,949

G

G

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chr12:44,921,530...44,929,504
Ensembl chr12:44,921,665...44,928,831

G

P

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chr 1:236,393,727...236,400,994
Ensembl chr 1:236,394,306...236,400,822

G

S

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chrNW_004936524:3,672,393...3,678,630
Ensembl chrNW_004936524:3,672,541...3,678,433

G

D

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chr11:52,205,619...52,211,281
Ensembl chr11:52,205,668...52,211,267

G

B

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chr 9:35,525,877...35,533,159
Ensembl chr 9:36,328,303...36,335,340

G

C

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

NCBI chrNW_004955472:619,084...625,570
Ensembl chrNW_004955472:619,245...625,051

G

H

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

RGD

NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159

G

R

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

RGD

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

M

carbonic anhydrase 9

disease_progression

DNA:SNP::rs2071676(human)

RGD

NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729

G

P

C-C motif chemokine ligand 4

NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,882...39,481,082

G

D

chemokine (C-C motif) ligand 4

NCBI chr 9:37,681,342...37,682,691
Ensembl chr 9:37,676,966...37,710,209

G

R

C-C motif chemokine ligand 4

RGD

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

M

C-C motif chemokine ligand 4

RGD

NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509

G

H

C-C motif chemokine ligand 4

RGD

NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621

G

N

C-C motif chemokine ligand 5

susceptibility
disease_progression

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614

G

G

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms:promoter:-403G>A,-28C>G (human)

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chr16:29,351,214...29,361,317

G

P

C-C motif chemokine ligand 5

susceptibility
disease_progression

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118

G

S

C-C motif chemokine ligand 5

susceptibility
disease_progression

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965

G

D

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms:promoter:-403G>A,-28C>G (human)

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

G

B

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms:promoter:-403G>A,-28C>G (human)

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172

G

C

C-C motif chemokine ligand 5

susceptibility
disease_progression

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

PMID:19017985 PMID:22576913 PMID:23336202 PMID:30536991

RGD:14401739 RGD:14995327 RGD:14995330 RGD:14995331

NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143

G

R

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

RGD

PMID:30536991 PMID:23336202 PMID:22576913 PMID:19017985

RGD:14401739, RGD:14995331, RGD:14995330, RGD:14995327

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

M

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

RGD

PMID:30536991 PMID:23336202 PMID:22576913 PMID:19017985

RGD:14401739, RGD:14995331, RGD:14995330, RGD:14995327

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

G

H

C-C motif chemokine ligand 5

disease_progression
susceptibility

DNA:polymorphisms:promoter:-403G>A,-28C>G (human)
DNA:polymorphisms: :

RGD

PMID:30536991 PMID:23336202 PMID:22576913 PMID:19017985

RGD:14401739, RGD:14995331, RGD:14995330, RGD:14995327

NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793

G

N

cyclin D2

disease_progression

DNA:SNP, haplotype:exon :rs1049606(human)
mRNA:decreased expression:Peripheral Blood Mononuclear Cell

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chrNW_004624860:1,383,015...1,405,107
Ensembl chrNW_004624860:1,382,948...1,405,107

G

G

cyclin D2

disease_progression

DNA:SNP, haplotype:exon :rs1049606(human)
mRNA:decreased expression:Peripheral Blood Mononuclear Cell

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

G

P

cyclin D2

disease_progression

DNA:SNP, haplotype:exon :rs1049606(human)
mRNA:decreased expression:Peripheral Blood Mononuclear Cell

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571

G

S

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chrNW_004936606:4,474,801...4,496,158
Ensembl chrNW_004936606:4,474,749...4,496,810

G

D

cyclin D2

disease_progression

DNA:SNP, haplotype:exon :rs1049606(human)
mRNA:decreased expression:Peripheral Blood Mononuclear Cell

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255

G

B

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chr12:4,385,957...4,417,602
Ensembl chr12:4,309,272...4,335,551

G

C

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

PMID:20414251 PMID:33320844

RGD:151664743 RGD:151664744

NCBI chrNW_004955413:2,083,351...2,108,450
Ensembl chrNW_004955413:2,083,351...2,103,430

G

R

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

RGD

PMID:33320844 PMID:20414251

RGD:151664743, RGD:151664744

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

M

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

RGD

PMID:33320844 PMID:20414251

RGD:151664743, RGD:151664744

NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156

G

H

cyclin D2

disease_progression

mRNA:decreased expression:Peripheral Blood Mononuclear Cell
DNA:SNP, haplotype:exon :rs1049606(human)

RGD

PMID:33320844 PMID:20414251

RGD:151664743, RGD:151664744

NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353

G

P

C-C motif chemokine receptor 2

NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,285,012...29,376,343

G

N

C-C motif chemokine receptor 3

NCBI chrNW_004624730:74,768,668...74,769,749
Ensembl chrNW_004624730:74,768,668...74,769,798

G

G

C-C motif chemokine receptor 3

NCBI chr22:7,648,410...7,698,523
Ensembl chr22:7,697,068...7,698,135

G

S

C-C motif chemokine receptor 3

NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739

G

D

C-C motif chemokine receptor 3

NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217

G

B

C-C motif chemokine receptor 3

NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630

G

C

C-C motif chemokine receptor 3

NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353

G

R

C-C motif chemokine receptor 3

RGD

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

M

C-C motif chemokine receptor 3

RGD

NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726

G

H

C-C motif chemokine receptor 3

RGD

NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706

G

G

C-C motif chemokine receptor 5

disease_progression
susceptibility

DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:SNP: : rs1799987(human)
DNA:polymorphism: :DNA:deletion:Cds:

PMID:17063508 PMID:27892677 PMID:29239247

RGD:14401574 RGD:14401575 RGD:14401727

NCBI chr22:7,803,794...7,818,112

G

P

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:polymorphism: :DNA:deletion:Cds:
DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T

PMID:17063508 PMID:27892677 PMID:29239247

RGD:14401574 RGD:14401575 RGD:14401727

NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895

G

D

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:polymorphism: :DNA:deletion:Cds:

PMID:17063508 PMID:27892677 PMID:29239247

RGD:14401574 RGD:14401575 RGD:14401727

NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952

G

B

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:polymorphism: :DNA:deletion:Cds:

PMID:17063508 PMID:27892677 PMID:29239247

RGD:14401574 RGD:14401575 RGD:14401727

NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379

G

R

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:polymorphism: :DNA:deletion:Cds:

RGD

PMID:29239247 PMID:17063508 PMID:27892677

RGD:14401574, RGD:14401727, RGD:14401575

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

G

M

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:polymorphism: :DNA:deletion:Cds:

RGD

PMID:29239247 PMID:17063508 PMID:27892677

RGD:14401574, RGD:14401727, RGD:14401575

NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736

G

H

C-C motif chemokine receptor 5

susceptibility
disease_progression

DNA:SNP: : rs1799987(human)
DNA:polymorphism:promoter:59029A>G,59353C>T
DNA:polymorphism: :DNA:deletion:Cds:

RGD

PMID:29239247 PMID:17063508 PMID:27892677

RGD:14401574, RGD:14401727, RGD:14401575

NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206

G

N

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chrNW_004624786:10,195,337...10,197,963

G

G

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chr16:6,956,633...6,959,645
Ensembl chr16:6,957,212...6,959,042

G

P

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chr12:52,874,754...52,877,256
Ensembl chr12:52,874,785...52,877,695

G

S

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chrNW_004936595:858,289...861,131

G

D

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chr 5:32,500,899...32,503,355
Ensembl chr 5:32,501,380...32,503,183

G

B

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chr17:7,610,725...7,613,696
Ensembl chr17:7,596,947...7,599,981

G

C

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

NCBI chrNW_004955467:9,340,490...9,343,912
Ensembl chrNW_004955467:9,341,364...9,343,836

G

R

Cd68 molecule

associated with inflammation;protein:increased expression:liver (human)

RGD

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

M

CD68 antigen

associated with inflammation;protein:increased expression:liver (human)

RGD

NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979

G

H

CD68 molecule

associated with inflammation;protein:increased expression:liver (human)

RGD

NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111

G

N

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324

G

G

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344

G

P

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103

G

S

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643

G

D

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874

G

B

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498

G

C

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460

G

R

cytotoxic T-lymphocyte-associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

RGD

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

M

cytotoxic T-lymphocyte-associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

RGD

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

G

H

cytotoxic T-lymphocyte associated protein 4

disease_progression

DNA:SNPs: :-1722T>C(rs733618), 49A>G(rs231775)6230G>A(rs3087243)(human)

RGD

NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965

G

N

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004624730:77,876,361...77,887,228
Ensembl chrNW_004624730:77,875,257...77,887,234

G

G

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

P

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311

G

S

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293

G

D

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927

G

B

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

G

C

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449

G

R

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

RGD

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

M

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

RGD

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

H

catenin beta 1

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

RGD

NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096

G

N

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910

G

G

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130

G

P

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948

G

S

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106

G

D

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979

G

B

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606

G

C

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927

G

R

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

RGD

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

M

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

RGD

NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748

G

H

C-X-C motif chemokine ligand 10

disease_progression

DNA:SNP:promoter:-201G>A(human)

RGD

NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497

G

G

cytochrome P450 family 27 subfamily B member 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443

G

P

cytochrome P450 family 27 subfamily B member 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,053,892...23,058,470

G

D

cytochrome P450 family 27 subfamily B member 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911

G

B

cytochrome P450 family 27 subfamily B member 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822

G

R

cytochrome P450, family 27, subfamily b, polypeptide 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

RGD

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

M

cytochrome P450, family 27, subfamily b, polypeptide 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

RGD

NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875

G

H

cytochrome P450 family 27 subfamily B member 1

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

RGD

NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986

G

M

cytochrome P450, family 2, subfamily a, polypeptide 5

CTD Direct Evidence: marker/mechanism

NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973

G

H

cytochrome P450 family 2 subfamily A member 6

CTD Direct Evidence: marker/mechanism

NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447

G

D

cytochrome P450, family 2, subfamily A, polypeptide 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:112,900,508...112,906,745
Ensembl chr 1:112,900,403...112,907,076

G

D

major histocompatibility complex, class II, DQ beta 1

treatment

PMID:29042702 PMID:29979894

RGD:14865006 RGD:14865007

NCBI chr12:2,305,307...2,307,711

G

N

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chrNW_004624736:4,959,482...5,195,182
Ensembl chrNW_004624736:4,959,634...5,193,928

G

G

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chr12:79,060,579...79,298,145
Ensembl chr12:79,060,425...79,298,164

G

P

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chr 1:221,257,771...221,491,889
Ensembl chr 1:221,256,009...221,491,953

G

S

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chrNW_004936503:4,362,573...4,575,307
Ensembl chrNW_004936503:4,363,926...4,574,932

G

D

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chr 1:89,152,456...89,379,203
Ensembl chr 1:89,150,856...89,378,013

G

B

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chr 9:6,791...256,837
Ensembl chr 9:201,156...446,910

G

C

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

NCBI chrNW_004955434:4,849,147...5,050,545
Ensembl chrNW_004955434:4,867,016...5,049,118

G

R

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

RGD

NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474

G

M

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

RGD

NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796

G

H

dedicator of cytokinesis 8

disease_progression

DNA:SNP::rs506121(human)

RGD

NCBI chr 9:211,257...465,255
Ensembl chr 9:214,854...465,259

G

N

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chrNW_004624795:407,228...435,578
Ensembl chrNW_004624795:407,598...438,734

G

G

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chr16:61,505,796...61,549,720
Ensembl chr16:61,505,825...61,551,890

G

P

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chr12:18,474,367...18,514,993
Ensembl chr12:18,474,097...18,517,479

G

S

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chrNW_004936541:1,216,584...1,259,355
Ensembl chrNW_004936541:1,217,138...1,257,935

G

D

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chr 9:18,585,918...18,631,743
Ensembl chr 9:18,585,971...18,635,570

G

B

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chr17:12,423,198...12,472,462
Ensembl chr17:12,595,715...12,644,147

G

C

elongation factor Tu GTP binding domain containing 2

susceptibility

NCBI chrNW_004955451:17,655,659...17,690,117
Ensembl chrNW_004955451:17,653,125...17,690,117

G

R

elongation factor Tu GTP binding domain containing 2

susceptibility

RGD

NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079

G

M

elongation factor Tu GTP binding domain containing 2

susceptibility

RGD

NCBI chr11:102,729,298...102,771,999
Ensembl chr11:102,729,299...102,771,811

G

H

elongation factor Tu GTP binding domain containing 2

susceptibility

RGD

NCBI chr17:44,849,948...44,899,445
Ensembl chr17:44,849,948...44,899,445

G

N

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chrNW_004624738:18,716,623...18,764,243
Ensembl chrNW_004624738:18,717,092...18,758,457

G

G

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chr14:70,246,081...70,290,851
Ensembl chr14:70,247,168...70,296,463

G

P

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chr 3:103,041,029...103,096,741
Ensembl chr 3:103,041,221...103,096,738

G

S

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chrNW_004936663:1,127,047...1,157,263
Ensembl chrNW_004936663:1,126,977...1,157,137

G

D

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chr17:29,494,641...29,537,933
Ensembl chr17:29,496,128...29,537,933

G

B

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chr2A:37,130,386...37,184,587
Ensembl chr2A:37,895,814...37,941,686

G

C

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

NCBI chrNW_004955441:4,908,318...4,944,343

G

R

eukaryotic translation initiation factor 2-alpha kinase 2

disease_progression

RGD

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

M

eukaryotic translation initiation factor 2-alpha kinase 2

disease_progression

RGD

NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002

G

H

eukaryotic translation initiation factor 2 alpha kinase 2

disease_progression

RGD

NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522

G

N

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848

G

P

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716

G

S

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chrNW_004936735:209,369...234,582

G

D

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321

G

B

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612

G

C

Fas cell surface death receptor

protein:increased expression:liver:

NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455

G

R

Fas cell surface death receptor

protein:increased expression:liver:

RGD

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

M

Fas cell surface death receptor

protein:increased expression:liver:

RGD

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

H

Fas cell surface death receptor

protein:increased expression:liver:

RGD

NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605

G

M

Fas ligand

protein:increased expression:liver:

RGD

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

N

Fas ligand

protein:increased expression:liver:

NCBI chrNW_004624771:9,031,978...9,038,760
Ensembl chrNW_004624771:9,032,016...9,038,825

G

G

Fas ligand

protein:increased expression:liver:

NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251

G

P

Fas ligand

protein:increased expression:liver:

NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464

G

S

Fas ligand

protein:increased expression:liver:

NCBI chrNW_004936481:14,789,547...14,795,780

G

D

Fas ligand

protein:increased expression:liver:

NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224

G

B

Fas ligand

protein:increased expression:liver:

NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281

G

C

Fas ligand

protein:increased expression:liver:

NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389

G

R

Fas ligand

protein:increased expression:liver:

RGD

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

H

Fas ligand

protein:increased expression:liver:

RGD

NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876

G

N

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004624738:29,108,759...29,190,725
Ensembl chrNW_004624738:29,108,809...29,191,368

G

G

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr14:59,276,380...59,375,635
Ensembl chr14:59,276,447...59,374,442

G

P

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr 3:92,696,402...92,792,623
Ensembl chr 3:92,696,441...92,792,616

G

S

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004936508:4,622,695...4,708,694
Ensembl chrNW_004936508:4,685,595...4,708,694

G

D

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr10:49,838,003...49,864,211
Ensembl chr10:49,838,776...49,925,064

G

B

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr2A:47,926,629...48,026,245
Ensembl chr2A:48,830,780...48,886,300

G

C

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chrNW_004955441:14,471,283...14,495,508
Ensembl chrNW_004955441:14,471,283...14,553,916

G

R

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662

G

M

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr17:88,298,287...88,373,473
Ensembl chr17:88,298,287...88,372,719

G

H

F-box protein 11

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

RGD

NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498

G

N

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679

G

G

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chr X:46,349,890...46,365,133

G

P

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chr X:43,303,777...43,328,164
Ensembl chr X:43,303,785...43,322,968

G

S

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308

G

D

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

G

B

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

G

C

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606

G

R

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

RGD

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

G

M

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

RGD

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

G

H

forkhead box P3

associated with hepatocellular carcinoma; protein:increased expression:liver

RGD

NCBI chr X:49,250,438...49,264,710
Ensembl chr X:49,250,438...49,264,800

G

M

histocompatibility 2, class II antigen A, alpha

disease_progression
susceptibility
no_association

DNA:polymorphisms: :
DNA:polymorphism: :HLA-DQA1*0102 (human)
DNA:polymorphism: :rs9272346(human)

RGD

PMID:20718347 PMID:17845309 PMID:24510573 PMID:30168489

RGD:14398754, RGD:126925986, RGD:14398837, RGD:14398755

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

G

M

histocompatibility 2, class II antigen A, beta 1

treatment

RGD

PMID:29979894 PMID:29042702

RGD:14865006, RGD:14865007

NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393

G

M

histocompatibility 2, P region alpha locus

disease_progression

DNA:SNP: :rs3077(human)

RGD

NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797

G

H

major histocompatibility complex, class II, DP alpha 1

disease_progression

DNA:SNP: :rs3077(human)

RGD

NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775

G

H

major histocompatibility complex, class II, DP beta 1

susceptibility
severity
disease_progression
treatment

DNA:SNP: :rs9277535(human)
DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:polymorphisms:3-UTR:rs9277534(human)
DNA:SNP: :rs7770370(human)

RGD

PMID:27051043 PMID:26197724 PMID:22496224 PMID:27083422

RGD:14694816, RGD:11553629, RGD:14694821, RGD:14694820

NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696

G

H

major histocompatibility complex, class II, DQ alpha 1

disease_progression
susceptibility
no_association

DNA:polymorphisms: :
DNA:polymorphism: :HLA-DQA1*0102 (human)
DNA:polymorphism: :rs9272346(human)

RGD

PMID:20718347 PMID:17845309 PMID:24510573 PMID:30168489

RGD:14398754, RGD:126925986, RGD:14398837, RGD:14398755

NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062

G

H

major histocompatibility complex, class II, DQ beta 1

treatment

RGD

PMID:29979894 PMID:29042702

RGD:14865006, RGD:14865007

NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383

G

P

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr 6:14,980,382...14,985,245

G

R

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

M

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804

G

H

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055

G

P

interferon, alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 1:201,515,835...201,516,477
Ensembl chr 1:201,515,809...201,516,488

G

R

interferon, alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

G

M

interferon alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893

G

H

interferon alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316

G

G

interferon alpha 2

treatment

CTD Direct Evidence: therapeutic

PMID:8509638 PMID:9339942 PMID:10836394 PMID:11112032

NCBI chr12:58,468,018...58,469,825

G

R

interferon alpha 2

treatment

RGD

NCBI chr 5:103,258,617...103,259,195

G

M

interferon alpha 2

treatment

RGD

NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149

G

H

interferon alpha 2

treatment

CTD Direct Evidence: therapeutic

CTD
RGD

PMID:9339942 PMID:10836394 PMID:11112032 PMID:8509638

NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398

G

N

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chrNW_004624745:21,434,234...21,470,099
Ensembl chrNW_004624745:21,433,758...21,468,889

G

G

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr 2:58,920,237...58,954,809
Ensembl chr 2:58,918,433...58,954,790

G

P

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr13:196,765,915...196,852,640
Ensembl chr13:196,766,087...196,852,635

G

S

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chrNW_004936500:9,060,975...9,091,618
Ensembl chrNW_004936500:9,060,182...9,091,661

G

D

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr31:27,860,094...27,891,361

G

B

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr21:19,593,032...19,628,651
Ensembl chr21:32,981,428...33,004,062

G

C

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chrNW_004955407:32,601,862...32,637,852
Ensembl chrNW_004955407:32,601,826...32,638,564

G

R

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

M

interferon (alpha and beta) receptor 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr16:91,166,517...91,202,477
Ensembl chr16:91,169,671...91,202,477

G

H

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

ClinVar
OMIM
CTD

PMID:16757563 PMID:25741868 PMID:28492532

NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,205,282...33,265,675

G

H

IFNAR2-IL10RB readthrough

ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr21:33,229,938...33,297,221
Ensembl chr21:33,229,892...33,297,160

G

N

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004624736:25,099,061...25,099,746

G

P

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495

G

S

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004936652:2,736,270...2,736,833

G

D

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855

G

B

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 9:20,884,742...20,886,317

G

C

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chrNW_004955434:23,301,623...23,302,304

G

R

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

M

interferon beta 1, fibroblast

CTD Direct Evidence: therapeutic

NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011

G

H

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942

G

N

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534

G

G

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473

G

P

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670

G

S

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452

G

D

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

G

B

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

G

C

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045

G

R

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

M

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

H

interferon gamma

CTD Direct Evidence: therapeutic

PMID:15994231 PMID:20610715

NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740

G

N

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chrNW_004624886:618,372...640,954
Ensembl chrNW_004624886:618,289...642,928

G

G

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr13:36,203,038...36,224,039
Ensembl chr13:36,203,004...36,222,542

G

P

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr 1:27,037,151...27,061,095
Ensembl chr 1:27,037,165...27,061,093

G

S

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chrNW_004936560:4,519,858...4,545,763
Ensembl chrNW_004936560:4,519,474...4,545,796

G

D

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578

G

B

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr 6:134,958,270...134,980,560
Ensembl chr 6:139,045,821...139,068,053

G

C

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chrNW_004955436:22,183,318...22,199,013

G

R

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

M

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977

G

H

interferon gamma receptor 1

susceptibility

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO
ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:10192386 PMID:11583830 PMID:12516030 PMID:16690980 PMID:18171304 More...

NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449

G

N

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732

G

G

interleukin 10

no_association
treatment

DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)
DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)

NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836

G

P

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378

G

S

interleukin 10

no_association
treatment

DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)
DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)

NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502

G

D

interleukin 10

no_association
treatment

DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)
DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)

NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057

G

B

interleukin 10

no_association
treatment

DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)
DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)

NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371

G

C

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779

G

R

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

RGD

PMID:27644568 PMID:27644568

RGD:14975150, RGD:14975150

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

M

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

RGD

PMID:27644568 PMID:27644568

RGD:14975150, RGD:14975150

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

H

interleukin 10

treatment
no_association

DNA:SNP, haplotypes:promoter:-1082G>A (rs1800896) (human)
DNA:SNPs:promoter:-592C>A (rs1800872), -819C>A (rs1800871) (human)

RGD

PMID:27644568 PMID:27644568

RGD:14975150, RGD:14975150

NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541

G

N

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chrNW_004624745:21,470,651...21,492,899
Ensembl chrNW_004624745:21,470,729...21,492,286

G

G

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr 2:58,885,166...58,919,687

G

P

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr13:196,853,606...196,884,237
Ensembl chr13:196,853,467...196,884,928

G

S

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chrNW_004936500:9,033,077...9,057,465
Ensembl chrNW_004936500:9,030,809...9,057,519

G

D

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr31:28,791,541...28,815,163
Ensembl chr31:27,892,394...27,915,637

G

B

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr21:19,628,808...19,668,268
Ensembl chr21:33,005,505...33,032,738

G

C

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chrNW_004955407:32,641,097...32,659,360
Ensembl chrNW_004955407:32,640,622...32,663,259

G

R

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

M

interleukin 10 receptor, beta

ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722

G

H

interleukin 10 receptor subunit beta

ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
ClinVar Annotator: match by term: HBV, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Hepatitis B virus, susceptibility to
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:16757563 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29248579

NCBI chr21:33,266,367...33,310,182
Ensembl chr21:33,266,367...33,311,420

G

N

interleukin 18

disease_progression
susceptibility

DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)
associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687

G

G

interleukin 18

disease_progression
susceptibility

DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)
associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150

G

P

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219

G

S

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189

G

D

interleukin 18

disease_progression
susceptibility

DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)
associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

G

B

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371

G

C

interleukin 18

disease_progression
susceptibility

DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)
associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)

PMID:19466545 PMID:27429592

RGD:14695540 RGD:14696658

NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634

G

R

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

RGD

PMID:27429592 PMID:19466545

RGD:14695540, RGD:14696658

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

M

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

RGD

PMID:27429592 PMID:19466545

RGD:14695540, RGD:14696658

NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140

G

H

interleukin 18

susceptibility
disease_progression

associated with hepatocellular carcinoma; DNA:SNP:promoter:-137G>C(rs187238)(human)
DNA:SNPs:promoter,intron,exon:��148G>C, +8925C>G,+13925A>C(human)

RGD

PMID:27429592 PMID:19466545

RGD:14695540, RGD:14696658

NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096

G

N

interleukin 2

NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453

G

G

interleukin 2

NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969

G

P

interleukin 2

NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609

G

S

interleukin 2

NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625

G

D

interleukin 2

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

G

B

interleukin 2

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

G

C

interleukin 2

NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265

G

R

interleukin 2

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

M

interleukin 2

RGD

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

H

interleukin 2

RGD

NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725

G

N

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304

G

G

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025

G

P

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,532,531...101,541,713

G

S

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883

G

D

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266

G

B

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915

G

C

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492

G

R

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

RGD

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

G

M

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

RGD

NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785

G

H

interleukin 21

mRNA:increased expression:spleen (C57BL/6N mouse)

RGD

NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066

G

N

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chrNW_004624782:13,009,450...13,015,548
Ensembl chrNW_004624782:13,009,564...13,015,440

G

G

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chr 5:26,348,559...26,358,028
Ensembl chr 5:26,348,848...26,356,360

G

P

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chr 3:18,421,962...18,427,916
Ensembl chr 3:18,421,981...18,427,915

G

S

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chrNW_004936501:11,972,715...11,978,152
Ensembl chrNW_004936501:11,973,385...11,976,583

G

D

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635

G

B

interleukin 27

exacerbates

mRNA:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

G

C

interleukin 27

exacerbates

protein:increased expression:blood serum (human)
mRNA:increased expression:blood plasma (human)

PMID:19081304 PMID:22766719 PMID:26925776

RGD:126790497 RGD:126790543 RGD:39128258

NCBI chrNW_004955493:6,712,005...6,717,417
Ensembl chrNW_004955493:6,712,005...6,717,417

G

R

interleukin 27

exacerbates

mRNA:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)

RGD

PMID:26925776 PMID:22766719 PMID:19081304

RGD:126790497, RGD:126790543, RGD:39128258

NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582

G

M

interleukin 27

exacerbates

mRNA:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)

RGD

PMID:26925776 PMID:22766719 PMID:19081304

RGD:126790497, RGD:126790543, RGD:39128258

NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113

G

H

interleukin 27

exacerbates

mRNA:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)

RGD

PMID:26925776 PMID:22766719 PMID:19081304

RGD:126790497, RGD:126790543, RGD:39128258

NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051

G

N

interleukin 2 receptor subunit beta

disease_progression

NCBI chrNW_004624752:10,662,053...10,682,891
Ensembl chrNW_004624752:10,672,432...10,683,045

G

G

interleukin 2 receptor subunit beta

disease_progression

NCBI chr19:19,830,919...19,853,534
Ensembl chr19:19,828,898...19,852,988

G

P

interleukin 2 receptor subunit beta

disease_progression

NCBI chr 5:10,610,094...10,650,315
Ensembl chr 5:10,628,962...10,650,314

G

S

interleukin 2 receptor subunit beta

disease_progression

NCBI chrNW_004936492:3,795,940...3,805,822
Ensembl chrNW_004936492:3,795,940...3,805,774

G

D

interleukin 2 receptor subunit beta

disease_progression

NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775

G

B

interleukin 2 receptor subunit beta

disease_progression

NCBI chr22:18,039,469...18,069,952
Ensembl chr22:35,874,898...35,899,038

G

C

interleukin 2 receptor subunit beta

disease_progression

NCBI chrNW_004955413:23,623,567...23,640,245
Ensembl chrNW_004955413:23,623,154...23,640,259

G

R

interleukin 2 receptor subunit beta

disease_progression

RGD

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

M

interleukin 2 receptor, beta chain

disease_progression

RGD

NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471

G

H

interleukin 2 receptor subunit beta

disease_progression

RGD

NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118

G

D

interleukin 32

treatment

human gene variant in a mouse model

NCBI chr 6:38,119,287...38,122,979

G

B

interleukin 32

treatment

human gene variant in a mouse model

NCBI chr16:2,007,018...2,023,757
Ensembl chr16:3,179,637...3,203,929

G

H

interleukin 32

treatment

human gene variant in a mouse model

RGD

NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192

G

N

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chrNW_004624733:39,412,800...39,420,079

G

G

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258

G

P

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365

G

D

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

G

B

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

G

C

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

NCBI chrNW_004955408:4,058,052...4,065,999

G

R

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

RGD

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

M

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

RGD

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

G

H

interleukin 4

treatment

DNA:SNPs: :rs2243250,rs2227284(human)

RGD

NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678

G

N

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318

G

G

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

G

P

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263

G

S

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chrNW_004936549:7,015,595...7,016,246

G

D

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

G

B

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chr 7:23,415,922...23,420,767

G

C

interleukin 6

DNA:SNP:promoter:-174C>G (human)

NCBI chrNW_004955410:25,079,835...25,084,390

G

R

interleukin 6

DNA:SNP:promoter:-174C>G (human)

RGD

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

M

interleukin 6

DNA:SNP:promoter:-174C>G (human)

RGD

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

H

interleukin 6

DNA:SNP:promoter:-174C>G (human)

RGD

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

N

interferon regulatory factor 1

disease_progression

NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526

G

G

interferon regulatory factor 1

disease_progression

NCBI chr23:35,309,058...35,317,765
Ensembl chr23:35,307,772...35,316,763

G

P

interferon regulatory factor 1

disease_progression

NCBI chr 2:134,776,122...134,783,646
Ensembl chr 2:134,776,129...134,783,801

G

S

interferon regulatory factor 1

disease_progression

NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636

G

D

interferon regulatory factor 1

disease_progression

NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608

G

B

interferon regulatory factor 1

disease_progression

NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035

G

C

interferon regulatory factor 1

disease_progression

NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973

G

R

interferon regulatory factor 1

disease_progression

RGD

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

M

interferon regulatory factor 1

disease_progression

RGD

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

G

H

interferon regulatory factor 1

disease_progression

RGD

NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719

G

N

lysine acetyltransferase 2A

treatment

NCBI chrNW_004624795:1,782,367...1,787,408
Ensembl chrNW_004624795:1,782,366...1,788,951

G

G

lysine acetyltransferase 2A

treatment

NCBI chr16:64,146,146...64,154,726
Ensembl chr16:64,146,207...64,154,252

G

P

lysine acetyltransferase 2A

treatment

NCBI chr12:20,638,493...20,647,464
Ensembl chr12:20,638,497...20,647,461

G

S

lysine acetyltransferase 2A

treatment

NCBI chrNW_004936490:16,952,698...16,960,424
Ensembl chrNW_004936490:16,952,363...16,960,489

G

D

lysine acetyltransferase 2A

treatment

NCBI chr 9:20,778,434...20,787,057
Ensembl chr 9:20,779,042...20,787,067

G

B

lysine acetyltransferase 2A

treatment

NCBI chr17:15,194,414...15,202,818
Ensembl chr17:15,416,075...15,424,197

G

C

lysine acetyltransferase 2A

treatment

NCBI chrNW_004955451:16,192,228...16,197,103
Ensembl chrNW_004955451:16,191,186...16,197,574

G

R

lysine acetyltransferase 2A

treatment

RGD

NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166

G

M

K(lysine) acetyltransferase 2A

treatment

RGD

NCBI chr11:100,595,572...100,603,293
Ensembl chr11:100,595,572...100,603,291

G

H

lysine acetyltransferase 2A

treatment

RGD

NCBI chr17:42,113,111...42,121,367
Ensembl chr17:42,113,111...42,121,367

G

H

killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1

susceptibility

DNA:deletion: (human)

RGD

PMID:31977279 PMID:29149205 PMID:24407110

RGD:150340579, RGD:150340588, RGD:150340587

G

P

killer cell lectin like receptor K1

treatment

PMID:17991774 PMID:28318408

RGD:38676490 RGD:39128174

NCBI chr 5:61,646,691...61,655,386
Ensembl chr 5:61,647,043...61,656,192

G

D

killer cell lectin like receptor K1

treatment

PMID:17991774 PMID:28318408

RGD:38676490 RGD:39128174

NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882

G

R

killer cell lectin like receptor K1

treatment

RGD

PMID:17991774 PMID:28318408

RGD:38676490, RGD:39128174

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

G

M

killer cell lectin-like receptor subfamily K, member 1

treatment

RGD

PMID:17991774 PMID:28318408

RGD:38676490, RGD:39128174

NCBI chr 6:129,587,286...129,600,863
Ensembl chr 6:129,587,286...129,600,827

G

H

killer cell lectin like receptor K1

treatment

RGD

NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874

G

B

interferon alpha-2

treatment

CTD Direct Evidence: therapeutic

PMID:8509638 PMID:9339942 PMID:10836394 PMID:11112032

NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736

G

B

HLA class II histocompatibility antigen, DQ beta 1 chain

treatment

PMID:29042702 PMID:29979894

RGD:14865006 RGD:14865007

NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272

G

B

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
severity
treatment
disease_progression

DNA:SNP: :rs9277535(human)
DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:SNP: :rs7770370(human)
DNA:polymorphisms:3-UTR:rs9277534(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387

G

B

HLA class II histocompatibility antigen, DP alpha 1 chain

disease_progression

DNA:SNP: :rs3077(human)

NCBI chr 6:32,637,826...32,646,501
Ensembl chr 6:33,752,638...33,761,417

G

N

HLA class II histocompatibility antigen, DP beta 1 chain

severity
susceptibility
disease_progression
treatment

DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:SNP: :rs9277535(human)
DNA:polymorphisms:3-UTR:rs9277534(human)
DNA:SNP: :rs7770370(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663

G

N

HLA class II histocompatibility antigen, DP alpha 1 chain

disease_progression

DNA:SNP: :rs3077(human)

NCBI chrNW_004624754:23,674,935...23,683,044
Ensembl chrNW_004624754:23,674,448...23,683,662

G

N

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chrNW_004624802:10,176,865...10,181,725
Ensembl chrNW_004624802:10,176,919...10,181,657

G

N

HLA class II histocompatibility antigen, DQ beta 1 chain

treatment

PMID:29042702 PMID:29979894

RGD:14865006 RGD:14865007

NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713

G

S

HLA class II histocompatibility antigen, DP alpha 1 chain

disease_progression

DNA:SNP: :rs3077(human)

NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907

G

S

HLA class II histocompatibility antigen, DP beta 1 chain

disease_progression
severity
treatment
susceptibility

DNA:polymorphisms:3-UTR:rs9277534(human)
DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:SNP: :rs7770370(human)
DNA:SNP: :rs9277535(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145

G

S

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:21,841,054...21,845,821

G

S

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chrNW_004936646:1,899,686...1,904,104
Ensembl chrNW_004936646:1,900,259...1,904,104

G

C

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

severity

DNA:SNP:promoter: -1260C>A (rs10877012) (human)

NCBI chrNW_004955458:5,472,404...5,477,001
Ensembl chrNW_004955458:5,472,404...5,477,001

G

C

HLA class II histocompatibility antigen, DP alpha 1 chain

disease_progression

DNA:SNP: :rs3077(human)

NCBI chrNW_004955437:1,644,037...1,657,094
Ensembl chrNW_004955437:1,643,238...1,651,071

G

C

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
severity
treatment
disease_progression

DNA:SNP: :rs9277535(human)
DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:SNP: :rs7770370(human)
DNA:polymorphisms:3-UTR:rs9277534(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042

G

N

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004624774:20,116,625...20,137,767
Ensembl chrNW_004624774:20,116,970...20,134,355

G

G

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr23:25,158,458...25,172,763
Ensembl chr23:25,157,269...25,172,757

G

P

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:125,595,115...125,607,026
Ensembl chr 2:125,591,789...125,607,594

G

S

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936575:2,526,067...2,533,996
Ensembl chrNW_004936575:2,524,342...2,533,559

G

D

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819

G

B

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:117,450,833...117,464,957
Ensembl chr 5:123,234,662...123,248,717

G

C

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004955521:178,290...193,926
Ensembl chrNW_004955521:185,792...193,926

G

R

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

M

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939

G

H

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413

G

N

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004624758:18,567,367...18,644,528
Ensembl chrNW_004624758:18,568,607...18,621,785

G

G

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:21,416,821...21,516,923
Ensembl chr 8:21,416,787...21,516,854

G

P

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704

G

S

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936555:6,781,563...6,865,662
Ensembl chrNW_004936555:6,781,321...6,865,768

G

D

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr25:34,095,858...34,186,775
Ensembl chr25:34,126,335...34,185,969

G

B

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:22,547,303...22,653,676
Ensembl chr 8:19,483,335...19,589,522

G

C

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004955403:46,503,226...46,583,807
Ensembl chrNW_004955403:46,504,440...46,584,016

G

R

lysyl oxidase-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067

G

M

lysyl oxidase-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283

G

H

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:23,296,897...23,404,120
Ensembl chr 8:23,296,897...23,425,328

G

N

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chrNW_004624749:6,332,686...6,495,942
Ensembl chrNW_004624749:6,332,534...6,495,942

G

G

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chr14:5,391,416...5,579,163
Ensembl chr14:5,391,449...5,583,916

G

P

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chr 3:52,483,028...52,649,480
Ensembl chr 3:52,484,274...52,649,410

G

S

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chrNW_004936713:515,388...616,024
Ensembl chrNW_004936713:435,238...612,835

G

D

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chr10:41,088,020...41,276,801
Ensembl chr10:41,089,371...41,276,891

G

B

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

Ensembl chr2A:102,750,221...102,945,263

G

C

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

NCBI chrNW_004955470:7,334,050...7,470,751
Ensembl chrNW_004955470:7,333,351...7,470,751

G

R

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

RGD

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

G

M

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

RGD

NCBI chr 1:39,939,806...40,065,470
Ensembl chr 1:39,940,073...40,065,470

G

H

mitogen-activated protein kinase kinase kinase kinase 4

associated with hepatocellular carcinoma;mRNA:increased expression:liver, blood serum (human)

RGD

NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690

G

D

mannose binding lectin 1

disease_progression

DNA:haplotype:promoter,exon:

NCBI chr 4:29,419,886...29,424,377

G

N

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297

G

G

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079

G

P

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083

G

B

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432

G

C

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006

G

R

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

RGD

NCBI chr 1:228,016,439...228,024,736

G

M

mannose-binding lectin (protein C) 2

disease_progression

DNA:haplotype:promoter,exon:

RGD

NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087

G

H

mannose binding lectin 2

disease_progression

DNA:haplotype:promoter,exon:

RGD

NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784

G

G

major histocompatibility complex, class II, DP alpha 1

disease_progression

DNA:SNP: :rs3077(human)

NCBI chr17:39,009,361...39,017,978

G

G

major histocompatibility complex, class II, DP beta 1

susceptibility
severity
disease_progression
treatment

DNA:SNP: :rs9277535(human)
DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:polymorphisms:3-UTR:rs9277534(human)
DNA:SNP: :rs7770370(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chr17:38,996,329...39,007,097

G

G

major histocompatibility complex, class II, DQ alpha 1

no_association
susceptibility
disease_progression

DNA:polymorphism: :rs9272346(human)
DNA:polymorphism: :HLA-DQA1*0102 (human)
DNA:polymorphisms: :

PMID:17845309 PMID:20718347 PMID:24510573 PMID:30168489

RGD:126925986 RGD:14398754 RGD:14398755 RGD:14398837

NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871

G

P

microRNA mir-100

CTD Direct Evidence: marker/mechanism

NCBI chr 9:49,157,909...49,157,988
Ensembl chr 9:49,157,909...49,157,988

G

R

microRNA 100

CTD Direct Evidence: marker/mechanism

NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304

G

M

microRNA 100

CTD Direct Evidence: marker/mechanism

NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800

G

H

microRNA 100

CTD Direct Evidence: marker/mechanism

NCBI chr11:122,152,229...122,152,308
Ensembl chr11:122,152,229...122,152,308

G

P

microRNA mir-122

severity

miRNA:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:22105316 PMID:28545106

NCBI chr 1:162,329,776...162,329,860
Ensembl chr 1:162,329,767...162,329,860

G

D

microRNA mir-122

severity

CTD Direct Evidence: marker/mechanism
miRNA:decreased expression:liver

PMID:22105316 PMID:28545106

NCBI chr 1:17,593,858...17,593,915
Ensembl chr 1:17,593,837...17,593,929

G

R

microRNA 122

severity

CTD Direct Evidence: marker/mechanism
miRNA:decreased expression:liver

CTD
RGD

PMID:28545106 PMID:22105316

NCBI chr18:58,758,703...58,758,787

G

M

microRNA 122

severity

CTD Direct Evidence: marker/mechanism
miRNA:decreased expression:liver

CTD
RGD

PMID:28545106 PMID:22105316

NCBI chr18:65,381,932...65,381,997
Ensembl chr18:65,381,932...65,381,997

G

H

microRNA 122

severity

CTD Direct Evidence: marker/mechanism
miRNA:decreased expression:liver

CTD
RGD

PMID:28545106 PMID:22105316

NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158

G

D

microRNA mir-125b-2

CTD Direct Evidence: marker/mechanism

NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052

G

M

microRNA 125b-2

CTD Direct Evidence: marker/mechanism

NCBI chr16:77,443,161...77,443,231
Ensembl chr16:77,443,161...77,443,231

G

R

microRNA 125b-2

CTD Direct Evidence: marker/mechanism

NCBI chr11:16,245,620...16,245,707

G

H

microRNA 125b-2

CTD Direct Evidence: marker/mechanism

NCBI chr21:16,590,237...16,590,325
Ensembl chr21:16,590,237...16,590,325

G

M

microRNA 146

ameliorates

RGD

NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288

G

H

microRNA 1468

CTD Direct Evidence: marker/mechanism

NCBI chr X:63,786,002...63,786,087
Ensembl chr X:63,786,002...63,786,087

G

R

microRNA 146a

ameliorates

RGD

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

G

H

microRNA 146a

ameliorates

RGD

NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450

G

P

microRNA mir-148a

CTD Direct Evidence: marker/mechanism

NCBI chr18:46,415,213...46,415,280
Ensembl chr18:46,415,202...46,415,281

G

D

microRNA mir-148a

CTD Direct Evidence: marker/mechanism

NCBI chr14:39,301,847...39,301,906
Ensembl chr14:39,301,843...39,301,920

G

R

microRNA 148a

CTD Direct Evidence: marker/mechanism

NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858

G

M

microRNA 148a

CTD Direct Evidence: marker/mechanism

NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890

G

H

microRNA 148a

CTD Direct Evidence: marker/mechanism

NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986

G

P

microRNA mir-155

NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902

G

D

microRNA mir-155

NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833

G

R

microRNA 155

RGD

NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718

G

M

microRNA 155

RGD

NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092

G

H

microRNA 155

RGD

NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044

G

R

microRNA 190

CTD Direct Evidence: marker/mechanism

NCBI chr 8:67,850,987...67,851,071
Ensembl chr 8:67,850,987...67,851,071

G

P

microRNA mir-190a

CTD Direct Evidence: marker/mechanism

NCBI chr 1:109,225,385...109,225,466
Ensembl chr 1:109,225,386...109,225,470

G

D

microRNA mir-190a

CTD Direct Evidence: marker/mechanism

NCBI chr30:27,433,122...27,433,206
Ensembl chr30:27,433,122...27,433,206

G

M

microRNA 190a

CTD Direct Evidence: marker/mechanism

NCBI chr 9:67,143,942...67,144,008
Ensembl chr 9:67,143,942...67,144,008

G

H

microRNA 190a

CTD Direct Evidence: marker/mechanism

NCBI chr15:62,823,957...62,824,041
Ensembl chr15:62,823,957...62,824,041

G

P

microRNA mir-192

CTD Direct Evidence: marker/mechanism

NCBI chr 2:7,285,667...7,285,746
Ensembl chr 2:7,285,667...7,285,746

G

D

microRNA mir-192

CTD Direct Evidence: marker/mechanism

NCBI chr18:52,281,129...52,281,193
Ensembl chr18:52,281,129...52,281,193

G

R

microRNA 192

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055

G

M

microRNA 192

CTD Direct Evidence: marker/mechanism

NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962

G

H

microRNA 192

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246

G

D

microRNA mir-193b

CTD Direct Evidence: marker/mechanism

NCBI chr 6:28,878,050...28,878,108
Ensembl chr 6:28,878,050...28,878,108

G

R

microRNA 193b

CTD Direct Evidence: marker/mechanism

NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824

G

M

microRNA 193b

CTD Direct Evidence: marker/mechanism

NCBI chr16:13,267,387...13,267,465
Ensembl chr16:13,267,387...13,267,465

G

H

microRNA 193b

CTD Direct Evidence: marker/mechanism

NCBI chr16:14,303,967...14,304,049
Ensembl chr16:14,303,967...14,304,049

G

R

microRNA 194-2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,564,761...203,564,845
Ensembl chr 1:203,564,761...203,564,845

G

M

microRNA 194-2

CTD Direct Evidence: marker/mechanism

NCBI chr19:6,314,673...6,314,758
Ensembl chr19:6,314,673...6,314,758

G

H

microRNA 194-2

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,891,355...64,891,439
Ensembl chr11:64,891,355...64,891,439

G

P

microRNA mir-204

CTD Direct Evidence: marker/mechanism

NCBI chr 1:224,065,494...224,065,602
Ensembl chr 1:224,065,494...224,065,602

G

D

microRNA mir-204

CTD Direct Evidence: marker/mechanism

NCBI chr 1:86,818,494...86,818,553
Ensembl chr 1:86,818,489...86,818,556

G

R

microRNA 204

CTD Direct Evidence: marker/mechanism

NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040

G

M

microRNA 204

CTD Direct Evidence: marker/mechanism

NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036

G

H

microRNA 204

CTD Direct Evidence: marker/mechanism

NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084

G

P

microRNA mir-28

CTD Direct Evidence: marker/mechanism

NCBI chr13:126,282,167...126,282,252
Ensembl chr13:126,282,167...126,282,252

G

D

microRNA mir-28

CTD Direct Evidence: marker/mechanism

NCBI chr34:20,971,517...20,971,578
Ensembl chr34:20,971,504...20,971,589

G

R

microRNA 28

CTD Direct Evidence: marker/mechanism

NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608

G

H

microRNA 28

CTD Direct Evidence: marker/mechanism

NCBI chr 3:188,688,781...188,688,866
Ensembl chr 3:188,688,781...188,688,866

G

M

microRNA 28a

CTD Direct Evidence: marker/mechanism

NCBI chr16:24,646,605...24,646,690
Ensembl chr16:24,646,605...24,646,690

G

P

microRNA mir-365-1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:28,908,137...28,908,216
Ensembl chr 3:28,908,129...28,908,219

G

D

microRNA mir-365-1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:28,873,135...28,873,221
Ensembl chr 6:28,873,126...28,873,235

G

M

microRNA 365-1

CTD Direct Evidence: marker/mechanism

NCBI chr16:13,271,704...13,271,790
Ensembl chr16:13,271,704...13,271,790

G

P

microRNA mir-365-2

CTD Direct Evidence: marker/mechanism

NCBI chr12:43,324,725...43,324,804
Ensembl chr12:43,324,728...43,324,809

G

D

microRNA mir-365-2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:41,303,092...41,303,202
Ensembl chr 9:41,303,092...41,303,202

G

M

microRNA 365-2

CTD Direct Evidence: marker/mechanism

NCBI chr11:79,617,226...79,617,337
Ensembl chr11:79,617,226...79,617,337

G

H

microRNA 365a

CTD Direct Evidence: marker/mechanism

NCBI chr16:14,309,285...14,309,371
Ensembl chr16:14,309,285...14,309,371

G

R

microRNA 365b

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,686,255...64,686,340
Ensembl chr10:64,686,252...64,686,351

G

H

microRNA 365b

CTD Direct Evidence: marker/mechanism

NCBI chr17:31,575,411...31,575,521
Ensembl chr17:31,575,411...31,575,521

G

D

microRNA mir-378

CTD Direct Evidence: marker/mechanism

NCBI chr 4:59,276,347...59,276,406
Ensembl chr 4:59,276,336...59,276,417

G

P

microRNA mir-378-1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:150,825,865...150,825,944
Ensembl chr 2:150,825,865...150,825,944

G

M

microRNA 378a

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,530,906...61,530,971
Ensembl chr18:61,530,906...61,530,971

G

H

microRNA 378a

CTD Direct Evidence: marker/mechanism

NCBI chr 5:149,732,825...149,732,890
Ensembl chr 5:149,732,825...149,732,890

G

H

microRNA 378i

CTD Direct Evidence: marker/mechanism

NCBI chr22:41,923,222...41,923,297
Ensembl chr22:41,923,222...41,923,297

G

P

microRNA mir-455

CTD Direct Evidence: marker/mechanism

NCBI chr 1:254,824,200...254,824,279
Ensembl chr 1:254,824,196...254,824,291

G

D

microRNA mir-455

CTD Direct Evidence: marker/mechanism

NCBI chr11:68,461,911...68,461,968
Ensembl chr11:68,461,896...68,461,983

G

R

microRNA 455

CTD Direct Evidence: marker/mechanism

NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390

G

M

microRNA 455

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,175,088...63,175,169
Ensembl chr 4:63,175,088...63,175,169

G

H

microRNA 455

CTD Direct Evidence: marker/mechanism

NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529

G

H

microRNA 6881

CTD Direct Evidence: marker/mechanism

NCBI chr15:74,411,357...74,411,432
Ensembl chr15:74,411,357...74,411,432

G

P

microRNA mir-885

CTD Direct Evidence: marker/mechanism

NCBI chr13:66,597,531...66,597,610
Ensembl chr13:66,597,531...66,597,610

G

D

microRNA mir-885

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602

G

H

microRNA 885

CTD Direct Evidence: marker/mechanism

NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562

G

P

microRNA mir-99a

CTD Direct Evidence: marker/mechanism

NCBI chr13:181,302,483...181,302,562
Ensembl chr13:181,302,478...181,302,567

G

R

microRNA 99a

CTD Direct Evidence: marker/mechanism

NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523

G

M

microRNA 99a

CTD Direct Evidence: marker/mechanism

NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888

G

H

microRNA 99a

CTD Direct Evidence: marker/mechanism

NCBI chr21:16,539,089...16,539,169
Ensembl chr21:16,539,089...16,539,169

G

D

microRNA mir-99a-1

CTD Direct Evidence: marker/mechanism

NCBI chr31:13,258,782...13,258,840
Ensembl chr31:13,258,782...13,258,840

G

D

microRNA mir-99a-2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:12,047,369...12,047,425
Ensembl chr 5:12,047,369...12,047,425

G

P

microRNA let-7c

CTD Direct Evidence: marker/mechanism

NCBI chr13:181,303,209...181,303,302
Ensembl chr13:181,303,209...181,303,302

G

D

microRNA let-7c

CTD Direct Evidence: marker/mechanism

NCBI chr31:13,259,522...13,259,588
Ensembl chr31:13,259,502...13,259,609

G

H

microRNA let-7c

CTD Direct Evidence: marker/mechanism

NCBI chr21:16,539,828...16,539,911
Ensembl chr21:16,539,828...16,539,911

G

M

microRNA let7c-1

CTD Direct Evidence: marker/mechanism

NCBI chr16:77,396,545...77,396,638
Ensembl chr16:77,396,545...77,396,638

G

R

microRNA let-7c-1

CTD Direct Evidence: marker/mechanism

NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265

G

N

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chrNW_004624892:2,656,260...2,671,455
Ensembl chrNW_004624892:2,656,260...2,669,946

G

G

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chr20:89,457,549...89,474,756
Ensembl chr20:89,459,493...89,474,352

G

P

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chr 6:167,896,191...167,908,988
Ensembl chr 6:167,896,287...167,908,625

G

S

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chrNW_004936474:24,744,673...24,757,189
Ensembl chrNW_004936474:24,744,673...24,757,085

G

D

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350

G

B

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chr 1:42,639,191...42,654,738
Ensembl chr 1:44,018,395...44,034,492

G

C

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

NCBI chrNW_004955537:2,922,156...2,937,223
Ensembl chrNW_004955537:2,922,156...2,937,223

G

R

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

RGD

NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797

G

M

myeloproliferative leukemia virus oncogene

mRNA:decreased expression:liver (human)

RGD

NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710

G

H

MPL proto-oncogene, thrombopoietin receptor

mRNA:decreased expression:liver (human)

RGD

NCBI chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466

G

N

methylenetetrahydrofolate reductase

no_association
susceptibility

DNA:missense mutations:cds:g.1298A>C, g.2756A>G
DNA:transition:cds:g.677C>T (human)

NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168

G

G

methylenetetrahydrofolate reductase

no_association
susceptibility

DNA:missense mutations:cds:g.1298A>C, g.2756A>G
DNA:transition:cds:g.677C>T (human)

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

G

P

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820

G

S

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

NCBI chrNW_004936474:623,438...637,849
Ensembl chrNW_004936474:623,291...638,193

G

D

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818

G

B

methylenetetrahydrofolate reductase

no_association
susceptibility

DNA:missense mutations:cds:g.1298A>C, g.2756A>G
DNA:transition:cds:g.677C>T (human)

NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419

G

C

methylenetetrahydrofolate reductase

no_association
susceptibility

DNA:missense mutations:cds:g.1298A>C, g.2756A>G
DNA:transition:cds:g.677C>T (human)

NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240

G

R

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

RGD

PMID:18222012 PMID:18222012

RGD:38508898, RGD:38508898

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

M

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

RGD

PMID:18222012 PMID:18222012

RGD:38508898, RGD:38508898

NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008

G

H

methylenetetrahydrofolate reductase

susceptibility
no_association

DNA:transition:cds:g.677C>T (human)
DNA:missense mutations:cds:g.1298A>C, g.2756A>G

RGD

PMID:18222012 PMID:18222012

RGD:38508898, RGD:38508898

NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455

G

N

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489

G

G

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166

G

P

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109

G

S

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372

G

D

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534

G

B

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chr 3:38,036,565...38,041,014
Ensembl chr 3:38,319,024...38,323,572

G

C

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138

G

R

MYD88, innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

RGD

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

M

myeloid differentiation primary response gene 88

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

RGD

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

G

H

MYD88 innate immune signal transduction adaptor

associated with hepatocellular carcinoma;protein:decreased expression:liver (human)

RGD

NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024

G

N

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205

G

G

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

P

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277

G

S

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612

G

D

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433

G

B

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chr14:16,155,331...16,158,588

G

C

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520

G

R

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

RGD

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

M

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

RGD

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

H

NFKB inhibitor alpha

susceptibility

DNA:SNPs:promoter:-826C>T, -881A>G (rs2233406, rs3138053) (human)

RGD

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

N

programmed cell death 1

disease_progression
susceptibility

DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)
DNA:SNP: :rs2227981(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chrNW_004624847:5,732,922...5,741,908
Ensembl chrNW_004624847:5,732,767...5,742,269

G

G

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chr10:127,877,383...127,886,234
Ensembl chr10:127,878,554...127,886,088

G

P

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chr15:140,337,353...140,347,493
Ensembl chr15:140,336,258...140,347,478

G

S

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587

G

D

programmed cell death 1

disease_progression
susceptibility

DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)
DNA:SNP: :rs2227981(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723

G

B

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chr12:130,849,353...130,858,776

G

C

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

PMID:28667037 PMID:29786123 PMID:31770816

RGD:40818272 RGD:40818414 RGD:40818423

NCBI chrNW_004955542:49,290...57,747
Ensembl chrNW_004955542:49,259...58,823

G

R

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

RGD

PMID:31770816 PMID:29786123 PMID:28667037

RGD:40818272, RGD:40818423, RGD:40818414

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

M

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

RGD

PMID:31770816 PMID:29786123 PMID:28667037

RGD:40818272, RGD:40818423, RGD:40818414

NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278

G

H

programmed cell death 1

disease_progression
susceptibility

DNA:SNP: :rs2227981(human)
DNA:SNPs,halptype: :rs36084323, rs2227981,rs2227982(human)

RGD

PMID:31770816 PMID:29786123 PMID:28667037 PMID:31770816

RGD:40818272, RGD:40818423, RGD:40818414, RGD:40818272

NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894

G

N

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559

G

G

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

G

P

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172

G

S

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877

G

D

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851

G

B

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136

G

C

plasminogen activator, urokinase

severity

protein:increased expression:plasma

NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209

G

R

plasminogen activator, urokinase

severity

protein:increased expression:plasma

RGD

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

M

plasminogen activator, urokinase

severity

protein:increased expression:plasma

RGD

NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453

G

H

plasminogen activator, urokinase

severity

protein:increased expression:plasma

RGD

NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496

G

N

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chrNW_004624907:1,174,648...1,188,919
Ensembl chrNW_004624907:1,174,448...1,189,377

G

G

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chr 6:37,161,957...37,191,867

G

P

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418

G

S

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chrNW_004936706:840,968...855,552

G

D

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880

G

B

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561

G

C

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324

G

R

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

RGD

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

G

M

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

RGD

NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393

G

H

plasminogen activator, urokinase receptor

severity

protein:increased expression:plasma

RGD

NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547

G

N

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chrNW_004624744:22,941,194...23,208,987
Ensembl chrNW_004624744:22,946,979...23,172,122

G

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr 8:63,781,892...64,061,222
Ensembl chr 8:63,781,948...64,060,864

G

P

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr 4:66,712,412...66,996,258
Ensembl chr 4:66,715,237...66,996,044

G

S

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chrNW_004936496:6,005,410...6,284,332
Ensembl chrNW_004936496:6,008,277...6,284,346

G

D

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr29:17,458,098...17,738,069
Ensembl chr29:17,458,281...17,735,170

G

B

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr 8:64,489,817...64,769,602
Ensembl chr 8:66,215,974...66,430,138

G

C

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chrNW_004955444:11,154,318...11,414,680
Ensembl chrNW_004955444:11,154,318...11,414,075

G

R

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068

G

M

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 1:11,063,496...11,373,907
Ensembl chr 1:11,063,689...11,373,905

G

H

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032

G

N

PRKCSH beta subunit of glucosidase II

treatment

NCBI chrNW_004624828:3,219,105...3,227,369
Ensembl chrNW_004624828:3,219,216...3,227,369

G

G

PRKCSH beta subunit of glucosidase II

treatment

NCBI chr 6:10,360,392...10,375,785
Ensembl chr 6:10,360,751...10,374,208

G

P

PRKCSH beta subunit of glucosidase II

treatment

NCBI chr 2:70,097,424...70,114,460
Ensembl chr 2:70,097,444...70,114,446

G

S

PRKCSH beta subunit of glucosidase II

treatment

NCBI chrNW_004936659:1,501,425...1,511,634
Ensembl chrNW_004936659:1,501,419...1,511,625

G

D

PRKCSH beta subunit of glucosidase II

treatment

NCBI chr20:49,905,246...49,916,551
Ensembl chr20:49,905,248...49,916,463

G

B

PRKCSH beta subunit of glucosidase II

treatment

NCBI chr19:10,981,398...10,997,062
Ensembl chr19:11,693,620...11,707,728

G

C

PRKCSH beta subunit of glucosidase II

treatment

NCBI chrNW_004955495:2,331,075...2,338,479
Ensembl chrNW_004955495:2,331,569...2,337,946

G

R

PRKCSH beta subunit of glucosidase II

treatment

RGD

NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492

G

M

protein kinase C substrate 80K-H

treatment

RGD

NCBI chr 9:21,914,314...21,925,521
Ensembl chr 9:21,914,102...21,925,518

G

H

PRKCSH beta subunit of glucosidase II

treatment

RGD

NCBI chr19:11,435,635...11,450,968
Ensembl chr19:11,435,284...11,450,968

G

N

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chrNW_004624791:13,975,235...14,056,900

G

G

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

P

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chr14:99,929,590...100,021,619

G

S

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323

G

D

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176

G

B

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

C

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829

G

R

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

RGD

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

M

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

RGD

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

G

H

phosphatase and tensin homolog

exacerbates

mRNA:decreased expression:liver (mouse)

RGD

NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930

G

N

ribonuclease L

NCBI chrNW_004624814:11,268,725...11,319,023
Ensembl chrNW_004624814:11,268,698...11,305,221

G

G

ribonuclease L

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

P

ribonuclease L

NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398

G

S

ribonuclease L

NCBI chrNW_004936481:7,165,400...7,177,342
Ensembl chrNW_004936481:7,165,353...7,177,538

G

D

ribonuclease L

NCBI chr 7:15,978,055...16,001,604
Ensembl chr 7:15,856,151...16,001,569

G

B

ribonuclease L

NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045

G

C

ribonuclease L

NCBI chrNW_004955406:21,413,950...21,424,860
Ensembl chrNW_004955406:21,411,980...21,425,052

G

R

ribonuclease L

RGD

NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704

G

M

ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)

RGD

NCBI chr 1:153,625,089...153,644,441
Ensembl chr 1:153,625,172...153,639,967

G

H

ribonuclease L

RGD

NCBI chr 1:182,573,634...182,589,256
Ensembl chr 1:182,573,634...182,589,256

G

R

RT1 class II, locus Ba

disease_progression
susceptibility
no_association

DNA:polymorphisms: :
DNA:polymorphism: :HLA-DQA1*0102 (human)
DNA:polymorphism: :rs9272346(human)

RGD

PMID:20718347 PMID:17845309 PMID:24510573 PMID:30168489

RGD:14398754, RGD:126925986, RGD:14398837, RGD:14398755

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

R

RT1 class II, locus Bb

treatment

RGD

PMID:29979894 PMID:29042702

RGD:14865006, RGD:14865007

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

G

R

RT1 class II, locus Ha

disease_progression

DNA:SNP: :rs3077(human)

RGD

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

G

R

RT1 class II, locus Hb, pseudogene 1

severity
susceptibility
treatment
disease_progression

DNA:SNPs, haplotype:3' utr:multiple (human)
DNA:SNP: :rs9277535(human)
DNA:SNP: :rs7770370(human)
DNA:polymorphisms:3-UTR:rs9277534(human)

PMID:22496224 PMID:26197724 PMID:27051043 PMID:27083422

RGD:11553629 RGD:14694816 RGD:14694820 RGD:14694821

NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618

G

N

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chrNW_004624842:2,591,016...2,649,746
Ensembl chrNW_004624842:2,591,148...2,647,742

G

G

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chr 2:57,641,634...57,699,685
Ensembl chr 2:57,639,046...57,699,525

G

P

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chr17:40,117,348...40,171,935
Ensembl chr17:40,107,462...40,171,878

G

S

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chrNW_004936561:4,180,607...4,238,623
Ensembl chrNW_004936561:4,180,546...4,229,036

G

D

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902

G

B

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chr20:33,224,200...33,282,018
Ensembl chr20:34,341,367...34,398,314

G

C

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

NCBI chrNW_004955422:24,714,103...24,780,672
Ensembl chrNW_004955422:24,735,161...24,778,830

G

R

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

RGD

NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386

G

M

SAM domain and HD domain, 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

RGD

NCBI chr 2:156,939,454...156,977,016
Ensembl chr 2:156,939,453...156,977,185

G

H

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

associated with hepatocellular carcinoma;DNA:insertion:exon 4: (human)

RGD

NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893

G

N

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chrNW_004624734:31,287,539...31,307,339
Ensembl chrNW_004624734:31,287,394...31,311,357

G

G

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chr24:47,018,237...47,034,360
Ensembl chr24:47,017,414...47,033,940

G

P

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chr 7:93,400,037...93,421,989
Ensembl chr 7:93,397,608...93,421,985

G

S

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chrNW_004936495:12,958,983...12,975,755
Ensembl chrNW_004936495:12,959,077...12,975,755

G

D

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chr 8:43,521,291...43,546,426
Ensembl chr 8:43,521,747...43,546,274

G

B

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chr14:50,369,663...50,390,984
Ensembl chr14:69,240,602...69,261,904

G

C

solute carrier family 10 member 1

ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:27882152 PMID:28835676 PMID:29658451

NCBI chrNW_004955466:597,081...609,254
Ensembl chrNW_004955466:597,204...608,756

G

R

solute carrier family 10 member 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:25550158 PMID:27882152 PMID:28835676 More...

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

M

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:25550158 PMID:27882152 PMID:28835676 More...

NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479

G

H

solute carrier family 10 member 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatitis B virus, resistance to

PMID:14660639 PMID:25418280 PMID:25550158 PMID:27882152 PMID:28835676 More...

NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241

G

N

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391

G

G

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928

G

P

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,656,077...95,763,472

G

S

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689

G

D

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894

G

B

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr2B:78,331,402...78,549,231
Ensembl chr2B:196,247,881...196,366,011

G

C

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276

G

R

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

G

M

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348

G

H

signal transducer and activator of transcription 4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,151,596

G

N

stimulator of interferon response cGAMP interactor 1

NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235

G

G

stimulator of interferon response cGAMP interactor 1

NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907

G

P

stimulator of interferon response cGAMP interactor 1

NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198

G

S

stimulator of interferon response cGAMP interactor 1

NCBI chrNW_004936531:8,555,966...8,562,829
Ensembl chrNW_004936531:8,555,637...8,562,885

G

D

stimulator of interferon response cGAMP interactor 1

NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072

G

B

stimulator of interferon response cGAMP interactor 1

NCBI chr 5:134,845,689...134,852,938
Ensembl chr 5:140,967,399...140,973,846

G

C

stimulator of interferon response cGAMP interactor 1

NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448

G

R

stimulator of interferon response cGAMP interactor 1

RGD

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

G

M

stimulator of interferon response cGAMP interactor 1

RGD

NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607

G

H

stimulator of interferon response cGAMP interactor 1

RGD

NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935

G

N

toll like receptor 2

treatment

NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833

G

G

toll like receptor 2

treatment

NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795

G

P

toll like receptor 2

treatment

NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330

G

S

toll like receptor 2

treatment

NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788

G

D

toll like receptor 2

treatment

NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241

G

B

toll like receptor 2

treatment

NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331

G

C

toll like receptor 2

treatment

NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258

G

R

toll-like receptor 2

treatment

RGD

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

M

toll-like receptor 2

treatment

RGD

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

G

H

toll like receptor 2

treatment

RGD

NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260

G

N

toll like receptor 3

disease_progression
susceptibility

DNA:SNPs, haplotype: rs3775291,rs5743305 (human)
DNA:SNP, haplotype: rs1879026(human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196

G

G

toll like receptor 3

disease_progression
susceptibility

DNA:SNPs, haplotype: rs3775291,rs5743305 (human)
DNA:SNP, haplotype: rs1879026(human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232

G

P

toll like receptor 3

susceptibility
disease_progression

DNA:SNP, haplotype: rs1879026(human)
DNA:SNPs, haplotype: rs3775291,rs5743305 (human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291

G

S

toll like receptor 3

susceptibility
disease_progression

DNA:SNP, haplotype: rs1879026(human)
DNA:SNPs, haplotype: rs3775291,rs5743305 (human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907

G

D

toll like receptor 3

susceptibility
disease_progression

DNA:SNP, haplotype: rs1879026(human)
DNA:SNPs, haplotype: rs3775291,rs5743305 (human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247

G

B

toll like receptor 3

susceptibility
disease_progression

DNA:SNP, haplotype: rs1879026(human)
DNA:SNPs, haplotype: rs3775291,rs5743305 (human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728

G

C

toll like receptor 3

susceptibility
disease_progression

DNA:SNP, haplotype: rs1879026(human)
DNA:SNPs, haplotype: rs3775291,rs5743305 (human)

PMID:22825813 PMID:30143709

RGD:21079424 RGD:21079431

NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467

G

R

toll-like receptor 3

disease_progression
susceptibility

DNA:SNPs, haplotype: rs3775291,rs5743305 (human)
DNA:SNP, haplotype: rs1879026(human)

RGD

PMID:30143709 PMID:22825813

RGD:21079424, RGD:21079431

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

G

M

toll-like receptor 3

disease_progression
susceptibility

DNA:SNPs, haplotype: rs3775291,rs5743305 (human)
DNA:SNP, haplotype: rs1879026(human)

RGD

PMID:30143709 PMID:22825813

RGD:21079424, RGD:21079431

NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117

G

H

toll like receptor 3

disease_progression
susceptibility

DNA:SNPs, haplotype: rs3775291,rs5743305 (human)
DNA:SNP, haplotype: rs1879026(human)

RGD

PMID:30143709 PMID:22825813

RGD:21079424, RGD:21079431

NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073

G

P

toll like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673

G

D

toll like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114

G

C

toll like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582

G

R

toll-like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

RGD

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

G

M

toll-like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

RGD

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

G

H

toll like receptor 9

susceptibility

DNA:SNP:exon:2848G>A (rs352140) (human)

RGD

NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645

G

N

tumor necrosis factor

no_association
severity
treatment

DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-857C>T (rs1799724) (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531

G

G

tumor necrosis factor

treatment
no_association
severity

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

G

P

tumor necrosis factor

severity
no_association
treatment

DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNP:promoter:-857C>T (rs1799724) (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416

G

S

tumor necrosis factor

severity
treatment
no_association

DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766

G

D

tumor necrosis factor

no_association
treatment
severity

DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

G

B

tumor necrosis factor

treatment
no_association
severity

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

G

C

tumor necrosis factor

treatment
no_association
severity

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)

PMID:12915457 PMID:27644568

RGD:14975150 RGD:14995438

NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700

G

R

tumor necrosis factor

treatment
severity
no_association

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)

RGD

PMID:27644568 PMID:12915457 PMID:27644568

RGD:14975150, RGD:14995438, RGD:14975150

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

M

tumor necrosis factor

treatment
severity
no_association

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)

RGD

PMID:27644568 PMID:12915457 PMID:27644568

RGD:14975150, RGD:14995438, RGD:14975150

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

H

tumor necrosis factor

treatment
severity
no_association

DNA:SNP:promoter:-857C>T (rs1799724) (human)
DNA:SNPs:promoter:-863C>A, -308A>G (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)

RGD

PMID:27644568 PMID:12915457 PMID:27644568

RGD:14975150, RGD:14995438, RGD:14975150

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

G

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

NCBI chr17:30,873,647...30,885,292
Ensembl chr17:30,873,666...30,886,967

G

P

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

NCBI chr 7:36,510,253...36,531,796
Ensembl chr 7:36,510,253...36,531,796

G

S

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647

G

D

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

NCBI chr12:9,990,678...10,000,195
Ensembl chr12:9,990,679...10,000,236

G

B

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

NCBI chr 6:40,861,283...40,874,446
Ensembl chr 6:42,163,337...42,183,091

G

R

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

RGD

NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203

G

M

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

RGD

NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952

G

H

triggering receptor expressed on myeloid cells 1

protein:increased expression:plasma

RGD

NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682

G

R

UDP glucuronosyltransferase family 1 member A1

susceptibility

DNA:SNP: : rs8175347(human)

RGD

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

M

UDP glucuronosyltransferase 1 family, polypeptide A1

susceptibility

DNA:SNP: : rs8175347(human)

RGD

NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719

G

H

UDP glucuronosyltransferase family 1 member A1

susceptibility

DNA:SNP: : rs8175347(human)

RGD

NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300

G

D

UDP glucuronosyltransferase 1 family, polypeptide A6

susceptibility

DNA:SNP: : rs2070959(human)

NCBI chr25:45,081,655...45,161,584
Ensembl chr25:45,032,130...45,160,941

G

R

UDP glucuronosyltransferase family 1 member A6

susceptibility

DNA:SNP: : rs2070959(human)

RGD

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

H

UDP glucuronosyltransferase family 1 member A6

susceptibility

DNA:SNP: : rs2070959(human)

RGD

NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300

G

M

UDP glucuronosyltransferase 1 family, polypeptide A6B

susceptibility

DNA:SNP: : rs2070959(human)

RGD

NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725

G

N

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chrNW_004624816:4,314,146...4,423,946
Ensembl chrNW_004624816:4,365,961...4,424,514

G

G

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

G

P

vitamin D receptor

susceptibility
disease_progression

DNA:polymorphisms, hapoltype: :
DNA:polymorphisms: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475

G

S

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109

G

D

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470

G

B

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192

G

C

vitamin D receptor

disease_progression
susceptibility

DNA:polymorphisms: :
DNA:polymorphisms, hapoltype: :

PMID:16733893 PMID:19693091

RGD:14401748 RGD:14402030

NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048

G

R

vitamin D receptor

susceptibility
disease_progression

DNA:polymorphisms, hapoltype: :
DNA:polymorphisms: :

RGD

PMID:16733893 PMID:19693091

RGD:14401748, RGD:14402030

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

G

M

vitamin D (1,25-dihydroxyvitamin D3) receptor

susceptibility
disease_progression

DNA:polymorphisms, hapoltype: :
DNA:polymorphisms: :

RGD

PMID:16733893 PMID:19693091

RGD:14401748, RGD:14402030

NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511

G

H

vitamin D receptor

susceptibility
disease_progression

DNA:polymorphisms, hapoltype: :
DNA:polymorphisms: :

RGD

PMID:16733893 PMID:19693091

RGD:14401748, RGD:14402030

NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048

G

N

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chrNW_004624907:1,087,611...1,113,275
Ensembl chrNW_004624907:1,087,611...1,113,266

G

G

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094

G

P

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729

G

S

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777

G

D

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816

G

B

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520

G

C

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

NCBI chrNW_004955555:1,293,416...1,315,839
Ensembl chrNW_004955555:1,293,416...1,315,839

G

R

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

RGD

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

M

X-ray repair complementing defective repair in Chinese hamster cells 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

RGD

NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865

G

H

X-ray repair cross complementing 1

susceptibility

DNA:missense mutation, haplotype:cds:p.R399Q (human)

RGD

NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473

G

N

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629

G

G

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960

G

P

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,193

G

S

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chrNW_004936474:19,714,145...19,722,512
Ensembl chrNW_004936474:19,714,153...19,722,528

G

D

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371

G

B

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556

G

C

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959

G

R

zinc finger CCCH type containing 12A

treatment

human gene in a mouse model

RGD

NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351

G

M

zinc finger CCCH type containing 12A

treatment

human gene in a mouse model

RGD

NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633

G

H

zinc finger CCCH-type containing 12A

treatment

human gene in a mouse model

RGD

NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377

Chronic Hepatitis B

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

N

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chrNW_004624885:2,783,058...2,839,688
Ensembl chrNW_004624885:2,812,448...2,839,693

G

G

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chr20:9,194,611...9,241,102
Ensembl chr20:9,219,937...9,241,329

G

P

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chr 4:95,154,230...95,197,308
Ensembl chr 4:95,154,358...95,197,304

G

S

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chrNW_004936580:4,183,016...4,208,341
Ensembl chrNW_004936580:4,183,079...4,203,435

G

D

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chr 7:42,762,021...42,785,192
Ensembl chr 7:42,748,136...42,782,999

G

B

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chr 1:129,937,993...129,983,747

G

C

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

NCBI chrNW_004955545:1,078,319...1,106,938
Ensembl chrNW_004955545:1,078,319...1,106,938

G

R

adenosine deaminase, RNA-specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

RGD

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

G

M

adenosine deaminase, RNA-specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

RGD

NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753

G

H

adenosine deaminase RNA specific

treatment

DNA:SNP:enhancer: (rs4845384) (human)

RGD

NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013

G

N

apolipoprotein A1

protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136

G

G

apolipoprotein A1

protein:decreased expression
mRNA, protein:decreased expression:liver, serum (human)
protein:decreased expression:plasma (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609

G

P

apolipoprotein A1

mRNA, protein:decreased expression:liver, serum (human)
protein:decreased expression:plasma (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713

G

S

apolipoprotein A1

protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chrNW_004936542:2,111,055...2,112,626
Ensembl chrNW_004936542:2,111,052...2,112,854

G

D

apolipoprotein A1

protein:decreased expression
protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943

G

B

apolipoprotein A1

protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122

G

C

apolipoprotein A1

protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

PMID:21726101 PMID:25115832 PMID:27015844

RGD:25671432 RGD:25671433 RGD:5508214

NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298

G

R

apolipoprotein A1

protein:decreased expression
protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

RGD

PMID:21726101 PMID:25115832 PMID:27015844

RGD:5508214, RGD:25671433, RGD:25671432

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

M

apolipoprotein A-I

protein:decreased expression
protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

RGD

PMID:21726101 PMID:25115832 PMID:27015844

RGD:5508214, RGD:25671433, RGD:25671432

NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764

G

H

apolipoprotein A1

protein:decreased expression
protein:decreased expression:plasma (human)
mRNA, protein:decreased expression:liver, serum (human)

RGD

PMID:21726101 PMID:25115832 PMID:27015844

RGD:5508214, RGD:25671433, RGD:25671432

NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622

G

N

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chrNW_004624907:1,752,322...1,755,308

G

G

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438

G

P

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330

G

S

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chrNW_004936706:1,512,438...1,516,805

G

D

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440

G

B

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490

G

C

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888

G

R

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

RGD

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

M

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

RGD

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

H

apolipoprotein E

susceptibility

DNA:missense mutations:cds:p.C112R, p.R158C (human)

RGD

NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393

G

D

B9 domain containing 2

no_association

DNA:SNPs:promoter:-509C>T (rs1800469) (human)
DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

G

N

baculoviral IAP repeat containing 3

ameliorates

NCBI chrNW_004624878:516,750...541,475
Ensembl chrNW_004624878:523,300...536,062

G

G

baculoviral IAP repeat containing 3

ameliorates

NCBI chr 1:93,692,239...93,711,905

G

P

baculoviral IAP repeat containing 3

ameliorates

NCBI chr 9:33,003,570...33,020,252
Ensembl chr 9:33,003,276...33,020,242

G

S

baculoviral IAP repeat containing 3

ameliorates

NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555

G

D

baculoviral IAP repeat containing 3

ameliorates

NCBI chr 5:29,324,893...29,343,322
Ensembl chr 5:29,325,331...29,337,240

G

B

baculoviral IAP repeat containing 3

ameliorates

NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194

G

C

baculoviral IAP repeat containing 3

ameliorates

NCBI chrNW_004955412:5,624,865...5,643,520
Ensembl chrNW_004955412:5,628,973...5,643,410

G

R

baculoviral IAP repeat-containing 3

ameliorates

RGD

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

M

baculoviral IAP repeat-containing 3

ameliorates

RGD

NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187

G

H

baculoviral IAP repeat containing 3

ameliorates

RGD

NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403

G

N

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chrNW_004624754:24,316,778...24,327,065
Ensembl chrNW_004624754:24,317,058...24,322,656

G

G

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chr17:40,069,852...40,094,478
Ensembl chr17:40,069,909...40,094,207

G

P

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chr 7:24,020,590...24,034,042
Ensembl chr 7:23,995,982...24,033,930

G

S

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chrNW_004936727:1,602,400...1,615,974
Ensembl chrNW_004936727:1,602,398...1,616,060

G

D

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chr12:1,363,656...1,399,732
Ensembl chr12:1,363,803...1,399,728

G

B

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chr 6:31,590,135...31,606,368

G

C

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

NCBI chrNW_004955437:449,171...460,898
Ensembl chrNW_004955437:448,672...460,519

G

R

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

RGD

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

G

M

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

RGD

NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241

G

H

complement C2

susceptibility

DNA:SNP:exon: p.Glu318Asp (human)

RGD

NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,673

G

G

C-C motif chemokine ligand 2

protein:decreased expression:serum:

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

G

P

chemokine (C-C motif) ligand 2

protein:decreased expression:serum:

NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026

G

D

C-C motif chemokine ligand 2

protein:decreased expression:serum:

NCBI chr 9:39,008,187...39,009,932

G

B

C-C motif chemokine ligand 2

protein:decreased expression:serum:

NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384

G

R

C-C motif chemokine ligand 2

protein:decreased expression:serum:

RGD

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

M

C-C motif chemokine ligand 2

protein:decreased expression:serum:

RGD

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

H

C-C motif chemokine ligand 2

protein:decreased expression:serum:

RGD

NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208

G

G

C-C motif chemokine ligand 4 like 2

protein:increased expression:blood serum (human)

NCBI chr16:29,565,468...29,567,911

G

H

C-C motif chemokine ligand 4 like 2

protein:increased expression:blood serum (human)

RGD

NCBI chr17:36,211,063...36,212,873
Ensembl chr17:36,210,924...36,212,878

G

N

C-C motif chemokine ligand 5

severity

NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614

G

G

C-C motif chemokine ligand 5

severity

NCBI chr16:29,351,214...29,361,317

G

P

C-C motif chemokine ligand 5

severity

NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118

G

S

C-C motif chemokine ligand 5

severity

NCBI chrNW_004936490:253,279...259,947
Ensembl chrNW_004936490:253,034...259,965

G

D

C-C motif chemokine ligand 5

severity

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

G

B

C-C motif chemokine ligand 5

severity

NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172

G

C

C-C motif chemokine ligand 5

severity

NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143

G

R

C-C motif chemokine ligand 5

severity

RGD

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

M

C-C motif chemokine ligand 5

severity

RGD

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

G

H

C-C motif chemokine ligand 5

severity

RGD

NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793

G

N

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833

G

G

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651

G

P

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691

G

S

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936560:42,561...45,748
Ensembl chrNW_004936560:42,537...45,807

G

D

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145

G

B

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077

G

C

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004955436:12,523,602...12,526,986
Ensembl chrNW_004955436:12,522,944...12,526,480

G

R

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

M

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

H

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372

G

N

CD163 molecule

protein:increased expression:blood serum (human)

NCBI chrNW_004624860:3,976,746...4,000,349
Ensembl chrNW_004624860:3,975,747...4,000,349

G

G

CD163 molecule

protein:increased expression:blood serum (human)

NCBI chr11:7,501,562...7,536,332
Ensembl chr11:7,501,150...7,536,295

G

P

CD163 molecule

protein:increased expression:blood serum (human)

NCBI chr 5:63,300,200...63,334,497
Ensembl chr 5:63,300,231...63,334,498

G

D

CD163 molecule

protein:increased expression:blood serum (human)

NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106

G

B

CD163 molecule

protein:increased expression:blood serum (human)

NCBI chr12:7,616,714...7,649,768
Ensembl chr12:7,775,343...7,810,023

G

R

CD163 molecule

protein:increased expression:blood serum (human)

RGD

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

M

CD163 antigen

protein:increased expression:blood serum (human)

RGD

NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486

G

H

CD163 molecule

protein:increased expression:blood serum (human)

RGD

NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893

G

G

CD1d molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061

G

P

CD1d molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr 4:92,096,670...92,101,177
Ensembl chr 4:92,094,700...92,101,095

G

D

CD1d molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr38:23,489,169...23,491,712

G

B

CD1d molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

NCBI chr 1:133,549,258...133,557,752
Ensembl chr 1:137,341,690...137,348,173

G

H

CD1d molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427

G

R

CD1d1 molecule

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089

G

M

CD1d1 antigen

associated with hepatocellular carcinoma;mRNA:increased expression:liver (human)

RGD

NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748

G

N

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814

G

G

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chr12:74,038,844...74,060,662
Ensembl chr12:74,041,767...74,056,806

G

P

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,041...216,792,724

G

S

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chrNW_004936539:132,870...145,288
Ensembl chrNW_004936539:132,868...143,602

G

D

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

G

B

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chr 9:5,269,270...5,289,629
Ensembl chr 9:5,454,391...5,474,402

G

C

CD274 molecule

treatment

protein:increased expression:regulatory T cell

PMID:20460044 PMID:26266813

RGD:11344683 RGD:41412166

NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904

G

R

CD274 molecule

treatment

protein:increased expression:regulatory T cell

RGD

PMID:26266813 PMID:20460044

RGD:11344683, RGD:41412166

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

M

CD274 antigen

treatment

protein:increased expression:regulatory T cell

RGD

PMID:26266813 PMID:20460044

RGD:11344683, RGD:41412166

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

G

H

CD274 molecule

treatment

protein:increased expression:regulatory T cell

RGD

PMID:26266813 PMID:20460044

RGD:11344683, RGD:41412166

NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566

G

N

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chrNW_004624736:1,296,589...1,367,259
Ensembl chrNW_004624736:1,297,420...1,369,200

G

G

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chr12:82,751,445...82,837,050
Ensembl chr12:82,752,995...82,837,042

G

P

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chr 1:224,960,875...225,042,378
Ensembl chr 1:224,960,875...225,042,308

G

S

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chrNW_004936503:7,750,353...7,826,408
Ensembl chrNW_004936503:7,750,352...7,825,554

G

D

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chr 1:85,944,255...86,020,955
Ensembl chr 1:85,945,557...86,019,195

G

B

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chr 9:53,044,517...53,129,875
Ensembl chr 9:70,428,899...70,493,952

G

C

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

NCBI chrNW_004955434:1,400,949...1,477,278
Ensembl chrNW_004955434:1,400,949...1,478,440

G

R

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

RGD

NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760

G

M

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

RGD

NCBI chr19:21,755,704...21,835,724
Ensembl chr19:21,755,706...21,835,724

G

H

cell migration inducing hyaluronidase 2

susceptibility

DNA:SNP:exon: p.Ser1254Asn (human)

RGD

NCBI chr 9:71,683,366...71,769,466
Ensembl chr 9:71,683,366...71,816,690

G

N

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324

G

G

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344

G

P

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103

G

S

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chrNW_004936631:484,356...489,643
Ensembl chrNW_004936631:484,356...489,643

G

D

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874

G

B

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498

G

C

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460

G

R

cytotoxic T-lymphocyte-associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

RGD

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

M

cytotoxic T-lymphocyte-associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

RGD

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

G

H

cytotoxic T-lymphocyte associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

RGD

NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965

G

N

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910

G

G

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130

G

P

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948

G

S

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106

G

D

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979

G

B

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606

G

C

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

PMID:18234638 PMID:30660173

RGD:27095888 RGD:27095951

NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927

G

R

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

RGD

PMID:30660173 PMID:18234638

RGD:27095888, RGD:27095951

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

M

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

RGD

PMID:30660173 PMID:18234638

RGD:27095888, RGD:27095951

NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748

G

H

C-X-C motif chemokine ligand 10

treatment

mRNA,protein:increased expression: peripheral blood mononuclear cell,serum, sinusoidal endothelium

RGD

PMID:30660173 PMID:18234638

RGD:27095888, RGD:27095951

NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497

G

M

C-X-C motif chemokine ligand 15

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

RGD

PMID:26265888 PMID:23890815

RGD:11075958, RGD:150520196

NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926

G

N

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293

G

G

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068

G

P

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861

G

D

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354

G

B

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083

G

C

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643

G

H

C-X-C motif chemokine ligand 8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

RGD

PMID:26265888 PMID:23890815

RGD:11075958, RGD:150520196

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716

G

D

major histocompatibility complex, class II, DQ beta 1

treatment
no_association

DNA:polymorphism: :HLA-DQB1*07(human)
DNA:SNP: :rs2856718 (human)
DNA:polymorphisms: :multiple
DNA:polymorphisms (human)

PMID:16237774 PMID:16893387 PMID:28267888 PMID:29287219

RGD:14865012 RGD:14974232 RGD:36049762 RGD:5147637

NCBI chr12:2,305,307...2,307,711

G

N

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chrNW_004624749:15,867,444...15,950,757
Ensembl chrNW_004624749:15,869,569...15,950,757

G

G

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chr14:18,135,973...18,209,471
Ensembl chr14:18,136,291...18,209,457

G

P

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245

G

S

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chrNW_004936712:413,602...454,443
Ensembl chrNW_004936712:414,446...454,449

G

D

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812

G

B

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468

G

C

eukaryotic translation initiation factor 2 alpha kinase 3

NCBI chrNW_004955424:210,867...279,267
Ensembl chrNW_004955424:226,038...280,593

G

R

eukaryotic translation initiation factor 2 alpha kinase 3

RGD

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

M

eukaryotic translation initiation factor 2 alpha kinase 3

RGD

NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229

G

H

eukaryotic translation initiation factor 2 alpha kinase 3

RGD

NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518

G

N

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679

G

G

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chr X:46,349,890...46,365,133

G

P

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chr X:43,303,777...43,328,164
Ensembl chr X:43,303,785...43,322,968

G

S

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308

G

D

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

G

B

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chr X:41,550,462...41,567,492
Ensembl chr X:49,402,652...49,417,029

G

C

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

PMID:18673437 PMID:21489307

RGD:38548921 RGD:38549358

NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606

G

R

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

RGD

PMID:18673437 PMID:21489307

RGD:38548921, RGD:38549358

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

G

M

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

RGD

PMID:18673437 PMID:21489307

RGD:38548921, RGD:38549358

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

G

H

forkhead box P3

mRNA,protein:increased expression:peripheral blood mononuclear cell, liver:

RGD

PMID:18673437 PMID:21489307

RGD:38548921, RGD:38549358

NCBI chr X:49,250,438...49,264,710
Ensembl chr X:49,250,438...49,264,800

G

N

glutamic--pyruvic transaminase

treatment
disease_progression

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chrNW_004624735:12,355,476...12,359,910
Ensembl chrNW_004624735:12,355,476...12,360,028

G

G

glutamic--pyruvic transaminase

treatment
disease_progression

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chr 8:138,716,802...138,721,421
Ensembl chr 8:138,718,767...138,721,251

G

S

glutamic--pyruvic transaminase

disease_progression
treatment

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chrNW_004936470:7,765,810...7,770,837
Ensembl chrNW_004936470:7,765,703...7,768,465

G

D

glutamic--pyruvic transaminase

treatment
disease_progression

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chr13:37,923,757...37,927,843
Ensembl chr13:37,924,422...37,926,156

G

B

glutamic--pyruvic transaminase

treatment
disease_progression

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

Ensembl chr 8:144,259,991...144,263,737

G

C

glutamic--pyruvic transaminase

disease_progression
treatment

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chrNW_004955454:3,127,997...3,132,459
Ensembl chrNW_004955454:3,127,997...3,132,459

G

R

glutamic--pyruvic transaminase

treatment
disease_progression

RGD

PMID:29279233 PMID:28007350

RGD:14975159, RGD:14975240

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

M

glutamic pyruvic transaminase, soluble

treatment
disease_progression

RGD

PMID:29279233 PMID:28007350

RGD:14975159, RGD:14975240

NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886

G

H

glutamic--pyruvic transaminase

treatment
disease_progression

RGD

PMID:29279233 PMID:28007350

RGD:14975159, RGD:14975240

NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174

G

M

histocompatibility 2, class II antigen A, alpha

treatment
susceptibility
disease_progression

DNA:polymorphisms: :
DNA:polymorphisms: :HLA-DQA1*0101/2/4, HLA-DQA1*0103 (human)
DNA:haplotype::
DNA:polymorphisms: :HLA-DQA1*0303, HLA-DQA1*0505(human)
DNA:polymorphism: :

RGD

PMID:27386643 PMID:30168489 PMID:22807686 PMID:16883532 PMID:15237447 More...

RGD:14398752, RGD:14398755, RGD:14398843, RGD:14398840, RGD:14398838, RGD:14398759

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

G

M

histocompatibility 2, class II antigen A, beta 1

treatment
no_association

DNA:polymorphisms (human)
DNA:polymorphism: :HLA-DQB1*07(human)
DNA:SNP: :rs2856718 (human)
DNA:polymorphisms: :multiple

RGD

PMID:16893387 PMID:16237774 PMID:28267888 PMID:29287219

RGD:5147637, RGD:36049762, RGD:14974232, RGD:14865012

NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393

G

M

histocompatibility 2, class II antigen E beta

disease_progression
susceptibility

DNA:haplotype::
DNA:polymorphisms: :

RGD

PMID:16883532 PMID:16237774

RGD:14398840, RGD:36049762

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

G

M

histocompatibility 2, P region alpha locus

treatment
disease_progression
susceptibility

CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)
mRNA:decreased expression:peripheral blood mononuclear cell:

CTD
RGD

PMID:19349983 PMID:29300980 PMID:28275747 PMID:30267609 PMID:30267609

RGD:14694973, RGD:14694818, RGD:14694817, RGD:14694817

NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797

G

H

major histocompatibility complex, class I, C

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130

G

H

major histocompatibility complex, class II, DP alpha 1

treatment
disease_progression
susceptibility

CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)
mRNA:decreased expression:peripheral blood mononuclear cell:

CTD
RGD

PMID:19349983 PMID:29300980 PMID:28275747 PMID:30267609 PMID:30267609

RGD:14694973, RGD:14694818, RGD:14694817, RGD:14694817

NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775

G

H

major histocompatibility complex, class II, DP beta 1

susceptibility
treatment
severity

CTD Direct Evidence: marker/mechanism
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:polymorphisms:multiple (human)
DNA:polymorphism: :(human)
DNA:SNPs:multiple (human)
DNA:SNP: :rs33054861(human)

CTD
RGD

PMID:19349983 PMID:28267888 PMID:19349983 PMID:22737229 PMID:21310144 More...

RGD:14974232, RGD:150429808, RGD:150429807, RGD:150429802, RGD:150429799, RGD:11536957, RGD:150429794, RGD:150429660, RGD:14694816

NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696

G

H

major histocompatibility complex, class II, DQ alpha 1

treatment
susceptibility
disease_progression

DNA:polymorphisms: :
DNA:polymorphisms: :HLA-DQA1*0101/2/4, HLA-DQA1*0103 (human)
DNA:haplotype::
DNA:polymorphisms: :HLA-DQA1*0303, HLA-DQA1*0505(human)
DNA:polymorphism: :

RGD

PMID:27386643 PMID:30168489 PMID:22807686 PMID:16883532 PMID:15237447 More...

RGD:14398752, RGD:14398755, RGD:14398843, RGD:14398840, RGD:14398838, RGD:14398759

NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062

G

H

major histocompatibility complex, class II, DQ beta 1

treatment
no_association

DNA:polymorphisms (human)
DNA:polymorphism: :HLA-DQB1*07(human)
DNA:SNP: :rs2856718 (human)
DNA:polymorphisms: :multiple

RGD

PMID:16893387 PMID:16237774 PMID:28267888 PMID:29287219

RGD:5147637, RGD:36049762, RGD:14974232, RGD:14865012

NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383

G

D

MHC class II DLA DRB1 beta chain

disease_progression
susceptibility

DNA:haplotype::
DNA:polymorphism:cds:HLA-DRB1*07 (human)
DNA:polymorphisms: :

PMID:16094724 PMID:16237774 PMID:16883532

RGD:14398840 RGD:36049762 RGD:40818403

NCBI chr12:2,151,409...2,164,564

G

H

major histocompatibility complex, class II, DR beta 1

disease_progression
susceptibility

DNA:haplotype::
DNA:polymorphism:cds:HLA-DRB1*07 (human)
DNA:polymorphisms: :

RGD

PMID:16883532 PMID:16094724 PMID:16237774

RGD:14398840, RGD:40818403, RGD:36049762

NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848

G

P

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr 6:14,980,382...14,985,245

G

R

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

M

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804

G

H

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055

G

N

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chrNW_004624780:3,684,941...3,697,506
Ensembl chrNW_004624780:3,685,069...3,697,474

G

G

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chr 8:37,930,910...37,950,790
Ensembl chr 8:37,930,562...37,946,505

G

P

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chr17:9,245,283...9,260,140
Ensembl chr17:9,245,196...9,260,473

G

S

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chrNW_004936843:658,058...672,662
Ensembl chrNW_004936843:657,979...672,700

G

D

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048

G

B

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chr 8:39,108,310...39,123,611
Ensembl chr 8:36,617,312...36,632,352

G

C

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

NCBI chrNW_004955536:2,944,770...2,955,829
Ensembl chrNW_004955536:2,943,611...2,955,829

G

R

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

RGD

NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730

G

M

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

RGD

NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025

G

H

indoleamine 2,3-dioxygenase 1

protein:increased expression:serum (human)

RGD

NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790

G

G

interferon alpha 2

susceptibility

CTD Direct Evidence: therapeutic
DNA:SNP:exon: p.Ala120Thr (human)

PMID:12802750 PMID:15340535 PMID:15751770 PMID:16246192 PMID:16476009 More...

NCBI chr12:58,468,018...58,469,825

G

R

interferon alpha 2

susceptibility

DNA:SNP:exon: p.Ala120Thr (human)

RGD

NCBI chr 5:103,258,617...103,259,195

G

M

interferon alpha 2

susceptibility

DNA:SNP:exon: p.Ala120Thr (human)

RGD

NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149

G

H

interferon alpha 2

susceptibility

CTD Direct Evidence: therapeutic
DNA:SNP:exon: p.Ala120Thr (human)

CTD
RGD

PMID:12802750 PMID:15340535 PMID:15751770 PMID:16246192 PMID:16476009 More...

NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398

G

N

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534

G

G

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473

G

P

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670

G

S

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452

G

D

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

G

B

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

G

C

interferon gamma

protein:decreased expression:serum (human)

PMID:26684441 PMID:28465467

RGD:14974255 RGD:39939037

NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045

G

R

interferon gamma

protein:decreased expression:serum (human)

RGD

PMID:26684441 PMID:28465467

RGD:14974255, RGD:39939037

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

M

interferon gamma

protein:decreased expression:serum (human)

RGD

PMID:26684441 PMID:28465467

RGD:14974255, RGD:39939037

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

H

interferon gamma

protein:decreased expression:serum (human)

RGD

PMID:26684441 PMID:28465467

RGD:14974255, RGD:39939037

NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740

G

R

interferon, lambda 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

RGD

NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235

G

H

interferon lambda 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

RGD

NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673

G

H

interferon lambda 4 (gene/pseudogene)

severity
disease_progression

DNA:SNP:5'utr: (rs12979860) (human)
DNA:frameshift mutation,substitution:5'utr: p.P70S (rs368234815, rs117648444)

RGD

PMID:25740255 PMID:28732143

RGD:40400752, RGD:40886279

NCBI chr19:39,246,314...39,248,856
Ensembl chr19:39,246,314...39,248,856

G

N

interleukin 12A

mRNA:increased expression:liver

NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940

G

G

interleukin 12A

mRNA:increased expression:liver

NCBI chr15:30,887,048...30,896,577
Ensembl chr15:30,887,897...30,894,550

G

P

interleukin 12A

mRNA:increased expression:liver

NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078

G

S

interleukin 12A

mRNA:increased expression:liver

NCBI chrNW_004936519:6,166,060...6,180,652
Ensembl chrNW_004936519:6,175,261...6,180,396

G

D

interleukin 12A

mRNA:increased expression:liver

NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550

G

B

interleukin 12A

mRNA:increased expression:liver

NCBI chr 3:157,011,675...157,019,897
Ensembl chr 3:165,061,505...165,068,666

G

C

interleukin 12A

mRNA:increased expression:liver

NCBI chrNW_004955448:10,611,131...10,617,911

G

R

interleukin 12A

mRNA:increased expression:liver

RGD

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

M

interleukin 12a

mRNA:increased expression:liver

RGD

NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880

G

H

interleukin 12A

mRNA:increased expression:liver

RGD

NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019

G

N

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589

G

G

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chr23:61,714,293...61,731,835

G

P

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,143,268...64,158,929

G

S

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chrNW_004936515:4,056,214...4,066,121
Ensembl chrNW_004936515:4,056,214...4,065,076

G

D

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

G

B

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chr 5:154,706,467...154,722,231
Ensembl chr 5:161,325,303...161,335,381

G

C

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620

G

R

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

RGD

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

M

interleukin 12b

susceptibility

DNA:SNP:3'utr: (rs3212227)

RGD

NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860

G

H

interleukin 12B

susceptibility

DNA:SNP:3'utr: (rs3212227)

RGD

NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863

G

N

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687

G

G

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150

G

P

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219

G

S

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189

G

D

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

G

B

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371

G

C

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634

G

R

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

RGD

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

M

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

RGD

NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140

G

H

interleukin 18

disease_progression

DNA:SNP:promoter:-607C>A(human)

RGD

NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096

G

N

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chrNW_004624749:6,795,822...6,873,068
Ensembl chrNW_004624749:6,795,748...6,873,701

G

G

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chr14:5,966,551...6,020,391
Ensembl chr14:6,005,061...6,020,265

G

P

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chr 3:51,868,549...51,902,454
Ensembl chr 3:51,846,792...51,951,383

G

S

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chrNW_004936713:1,020,969...1,035,012
Ensembl chrNW_004936713:1,021,044...1,035,039

G

D

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357

G

B

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

G

C

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

PMID:27180842 PMID:28381383

RGD:39457933 RGD:39938857

NCBI chrNW_004955470:7,779,828...7,849,157

G

R

interleukin 1 receptor-like 1

severity

protein:increased expression:serum:

RGD

PMID:27180842 PMID:28381383

RGD:39457933, RGD:39938857

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

M

interleukin 1 receptor-like 1

severity

protein:increased expression:serum:

RGD

PMID:27180842 PMID:28381383

RGD:39457933, RGD:39938857

NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575

G

H

interleukin 1 receptor like 1

severity

protein:increased expression:serum:

RGD

PMID:27180842 PMID:28381383

RGD:39457933, RGD:39938857

NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037

G

N

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453

G

G

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969

G

P

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609

G

S

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625

G

D

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

G

B

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

G

C

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265

G

R

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

M

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

RGD

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

H

interleukin 2

susceptibility

DNA:polymorphism:promoter:-385T>G(human)

RGD

NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725

G

N

interleukin 21

exacerbates
treatment
susceptibility

protein:decreased expression:blood serum (human)
DNA:SNPs:introns: (rs2221903, rs907715) (human)
associated with non-alcoholic fatty liver disease
protein:increased expression:blood serum (human)
DNA:SNP:intron: (rs2221903) (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304

G

G

interleukin 21

susceptibility
exacerbates
treatment

DNA:SNP:intron: (rs2221903) (human)
protein:decreased expression:blood serum (human)
associated with non-alcoholic fatty liver disease
protein:increased expression:blood serum (human)
DNA:SNPs:introns: (rs2221903, rs907715) (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025

G

P

interleukin 21

treatment
susceptibility
exacerbates

DNA:SNP:intron: (rs2221903) (human)
DNA:SNPs:introns: (rs2221903, rs907715) (human)
associated with non-alcoholic fatty liver disease
protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,532,531...101,541,713

G

S

interleukin 21

treatment
susceptibility
exacerbates

DNA:SNPs:introns: (rs2221903, rs907715) (human)
DNA:SNP:intron: (rs2221903) (human)
associated with non-alcoholic fatty liver disease
protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883

G

D

interleukin 21

treatment
exacerbates
susceptibility

protein:increased expression:blood serum (human)
associated with non-alcoholic fatty liver disease
protein:decreased expression:blood serum (human)
DNA:SNP:intron: (rs2221903) (human)
DNA:SNPs:introns: (rs2221903, rs907715) (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266

G

B

interleukin 21

exacerbates
treatment
susceptibility

protein:decreased expression:blood serum (human)
DNA:SNPs:introns: (rs2221903, rs907715) (human)
protein:increased expression:blood serum (human)
associated with non-alcoholic fatty liver disease
DNA:SNP:intron: (rs2221903) (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915

G

C

interleukin 21

exacerbates
treatment
susceptibility

protein:increased expression:blood serum (human)
associated with non-alcoholic fatty liver disease
DNA:SNPs:introns: (rs2221903, rs907715) (human)
protein:decreased expression:blood serum (human)
DNA:SNP:intron: (rs2221903) (human)

PMID:23354321 PMID:25243706 PMID:26840345 PMID:28500636 PMID:29879024 More...

RGD:127285353 RGD:127285361 RGD:127285364 RGD:127285369 RGD:127285378 RGD:127285539 RGD:127285549 RGD:127285551

NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492

G

R

interleukin 21

susceptibility
treatment
exacerbates

DNA:SNP:intron: (rs2221903) (human)
associated with non-alcoholic fatty liver disease
DNA:SNPs:introns: (rs2221903, rs907715) (human)
protein:increased expression:blood serum (human)
protein:decreased expression:blood serum (human)

RGD

PMID:23354321 PMID:31281514 PMID:26840345 PMID:29879024 PMID:25243706 More...

RGD:127285353, RGD:127285551, RGD:127285549, RGD:127285539, RGD:127285378, RGD:127285369, RGD:127285364, RGD:127285361

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

G

M

interleukin 21

susceptibility
treatment
exacerbates

DNA:SNP:intron: (rs2221903) (human)
associated with non-alcoholic fatty liver disease
DNA:SNPs:introns: (rs2221903, rs907715) (human)
protein:increased expression:blood serum (human)
protein:decreased expression:blood serum (human)

RGD

PMID:23354321 PMID:31281514 PMID:26840345 PMID:29879024 PMID:25243706 More...

RGD:127285353, RGD:127285551, RGD:127285549, RGD:127285539, RGD:127285378, RGD:127285369, RGD:127285364, RGD:127285361

NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785

G

H

interleukin 21

susceptibility
treatment
exacerbates

DNA:SNP:intron: (rs2221903) (human)
associated with non-alcoholic fatty liver disease
DNA:SNPs:introns: (rs2221903, rs907715) (human)
protein:increased expression:blood serum (human)
protein:decreased expression:blood serum (human)

RGD

PMID:23354321 PMID:31281514 PMID:26840345 PMID:29879024 PMID:25243706 More...

RGD:127285353, RGD:127285551, RGD:127285549, RGD:127285539, RGD:127285378, RGD:127285369, RGD:127285364, RGD:127285361

NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066

G

P

interleukin 29 (interferon, lambda 1)

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:51,484,658...51,485,233
Ensembl chr17:51,484,658...51,485,233

G

D

interleukin 29-like

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017

G

D

interleukin 32

exacerbates

mRNA, protein:increased expression:liver (human)

NCBI chr 6:38,119,287...38,122,979

G

B

interleukin 32

exacerbates

mRNA, protein:increased expression:liver (human)

NCBI chr16:2,007,018...2,023,757
Ensembl chr16:3,179,637...3,203,929

G

H

interleukin 32

exacerbates

mRNA, protein:increased expression:liver (human)

RGD

NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192

G

N

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864

G

G

interleukin 33

treatment
severity

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436

G

P

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840

G

S

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chrNW_004936539:763,755...791,461
Ensembl chrNW_004936539:623,248...791,470

G

D

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721

G

B

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624

G

C

interleukin 33

severity
treatment

PMID:25714983 PMID:27180842

RGD:39457933 RGD:39938954

NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948

G

R

interleukin 33

severity
treatment

RGD

PMID:27180842 PMID:25714983

RGD:39457933, RGD:39938954

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

M

interleukin 33

severity
treatment

RGD

PMID:27180842 PMID:25714983

RGD:39457933, RGD:39938954

NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118

G

H

interleukin 33

severity
treatment

RGD

PMID:27180842 PMID:25714983

RGD:39457933, RGD:39938954

NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983

G

N

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chrNW_004624733:39,412,800...39,420,079

G

G

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258

G

P

interleukin 4

treatment
disease_progression

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365

G

D

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

G

B

interleukin 4

treatment
disease_progression

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

G

C

interleukin 4

treatment
disease_progression

DNA:SNP:promoter:-590C>T (human)

PMID:21331994 PMID:26281177

RGD:14696675 RGD:14696697

NCBI chrNW_004955408:4,058,052...4,065,999

G

R

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

RGD

PMID:26281177 PMID:21331994

RGD:14696675, RGD:14696697

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

M

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

RGD

PMID:26281177 PMID:21331994

RGD:14696675, RGD:14696697

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

G

H

interleukin 4

disease_progression
treatment

DNA:SNP:promoter:-590C>T (human)

RGD

PMID:26281177 PMID:21331994

RGD:14696675, RGD:14696697

NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678

G

N

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chrNW_004624822:4,397,704...4,411,562
Ensembl chrNW_004624822:4,397,744...4,411,406

G

G

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chr22:14,194,979...14,216,180
Ensembl chr22:14,195,701...14,213,603

G

P

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chr13:34,928,455...34,948,250
Ensembl chr13:34,928,439...34,948,229

G

S

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chrNW_004936473:3,573,282...3,589,345
Ensembl chrNW_004936473:3,573,384...3,589,345

G

D

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

G

B

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chr 3:52,754,664...52,774,867
Ensembl chr 3:53,980,668...53,998,038

G

C

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

NCBI chrNW_004955430:2,772,064...2,787,912
Ensembl chrNW_004955430:2,770,373...2,789,131

G

R

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

RGD

NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708

G

M

inter alpha-trypsin inhibitor, heavy chain 4

protein:increased expression:serum

RGD

NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310

G

H

inter-alpha-trypsin inhibitor heavy chain 4

protein:increased expression:serum

RGD

NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688

G

N

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chrNW_004624742:29,631,391...29,723,981
Ensembl chrNW_004624742:29,689,965...29,723,981

G

G

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chr20:68,122,134...68,253,361
Ensembl chr20:68,122,173...68,252,042

G

P

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chr 6:147,320,288...147,567,188
Ensembl chr 6:147,429,056...147,567,182

G

S

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chrNW_004936692:2,298,149...2,354,084
Ensembl chrNW_004936692:2,299,504...2,354,132

G

D

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571

G

B

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chr 1:64,083,562...64,315,909
Ensembl chr 1:65,973,904...66,024,991

G

C

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

NCBI chrNW_004955423:25,501,989...25,581,826
Ensembl chrNW_004955423:25,524,075...25,580,604

G

R

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

RGD

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

M

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

RGD

NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479

G

H

Janus kinase 1

disease_progression

DNA:SNPs: :rs4244165, rs17127024 (human)

RGD

NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754

G

N

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chrNW_004624828:2,580,812...2,595,023
Ensembl chrNW_004624828:2,580,861...2,595,275

G

G

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chr 6:9,515,789...9,526,699
Ensembl chr 6:9,515,416...9,522,797

G

P

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382

G

S

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chrNW_004936659:785,059...793,775
Ensembl chrNW_004936659:782,340...793,688

G

D

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chr20:50,651,070...50,661,178
Ensembl chr20:50,650,711...50,658,496

G

B

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chr19:10,037,544...10,055,091
Ensembl chr19:10,701,303...10,717,604

G

C

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

NCBI chrNW_004955495:1,704,695...1,711,339
Ensembl chrNW_004955495:1,704,695...1,711,290

G

R

Kelch-like ECH-associated protein 1

mRNA:decreased expression:liver (human)

RGD

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

M

kelch-like ECH-associated protein 1

mRNA:decreased expression:liver (human)

RGD

NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657

G

H

kelch like ECH associated protein 1

mRNA:decreased expression:liver (human)

RGD

NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558

G

H

killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1

treatment
disease_progression
severity
ameliorates

DNA:deletion: (human)
associated with human immunodeficiency virus infectious disease;DNA:deletion: (human)

RGD

PMID:29075265 PMID:18074414 PMID:29947340 PMID:29032460 PMID:29330418

RGD:150340562, RGD:150340573, RGD:150340571, RGD:150340569, RGD:150340568

G

G

killer cell lectin like receptor C1

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

NCBI chr11:10,286,280...10,294,853
Ensembl chr11:10,286,787...10,293,585

G

R

killer cell lectin like receptor C1

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425

G

M

killer cell lectin-like receptor subfamily C, member 1

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

RGD

NCBI chr 6:129,642,978...129,659,815
Ensembl chr 6:129,642,978...129,655,936

G

H

killer cell lectin like receptor C1

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

RGD

NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685

G

P

killer cell lectin like receptor K1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

NCBI chr 5:61,646,691...61,655,386
Ensembl chr 5:61,647,043...61,656,192

G

D

killer cell lectin like receptor K1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

NCBI chr27:35,634,938...35,658,978
Ensembl chr27:35,639,280...35,658,882

G

B

killer cell lectin like receptor K1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

NCBI chr12:10,411,932...10,429,256
Ensembl chr12:10,662,424...10,699,078

G

R

killer cell lectin like receptor K1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

RGD

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

G

M

killer cell lectin-like receptor subfamily K, member 1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

RGD

NCBI chr 6:129,587,286...129,600,863
Ensembl chr 6:129,587,286...129,600,827

G

H

killer cell lectin like receptor K1

susceptibility

DNA:SNP:intron 1:(rs2617160) (human)

RGD

NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874

G

N

keratin 18

severity
disease_progression

protein:increased degradation:serum (human)
protein:increased phosphorylation:liver (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416

G

G

keratin 18

severity
disease_progression

protein:increased degradation:serum (human)
protein:increased phosphorylation:liver (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chr11:49,073,733...49,081,706

G

P

keratin 18

severity
disease_progression

protein:increased degradation:serum (human)
protein:increased phosphorylation:liver (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chr 5:18,217,686...18,221,432
Ensembl chr 5:18,217,691...18,221,429

G

S

keratin 18

disease_progression
severity

protein:increased phosphorylation:liver (human)
protein:increased degradation:serum (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chrNW_004936512:10,290,706...10,294,647
Ensembl chrNW_004936512:10,290,690...10,294,651

G

D

keratin 18

severity
disease_progression

protein:increased degradation:serum (human)
protein:increased phosphorylation:liver (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chr27:2,189,269...2,193,368
Ensembl chr27:2,189,269...2,193,368

G

B

keratin 18

disease_progression
severity

protein:increased phosphorylation:liver (human)
protein:increased degradation:serum (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196

G

C

keratin 18

severity
disease_progression

protein:increased degradation:serum (human)
protein:increased phosphorylation:liver (human)

PMID:20334631 PMID:28579343

RGD:18337487 RGD:18337494

NCBI chrNW_004955458:227,017...230,752
Ensembl chrNW_004955458:226,805...232,728

G

R

keratin 18

disease_progression
severity

protein:increased phosphorylation:liver (human)
protein:increased degradation:serum (human)

RGD

PMID:20334631 PMID:28579343

RGD:18337487, RGD:18337494

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

M

keratin 18

disease_progression
severity

protein:increased phosphorylation:liver (human)
protein:increased degradation:serum (human)

RGD

PMID:20334631 PMID:28579343

RGD:18337487, RGD:18337494

NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462

G

H

keratin 18

disease_progression
severity

protein:increased phosphorylation:liver (human)
protein:increased degradation:serum (human)

RGD

PMID:20334631 PMID:28579343

RGD:18337487, RGD:18337494

NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906

G

N

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chrNW_004624742:29,221,742...29,313,273
Ensembl chrNW_004624742:29,223,392...29,337,049

G

G

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229

G

P

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995

G

S

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444

G

D

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636

G

B

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768

G

C

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407

G

R

leptin receptor

mRNA:altered exression:PBMC,liver

RGD

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

M

leptin receptor

mRNA:altered exression:PBMC,liver

RGD

NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549

G

H

leptin receptor

mRNA:altered expression:liver, peripheral blood mononuclear cell

RGD

NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559

G

P

NKG2-A/NKG2-B type II integral membrane protein

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

NCBI chr 5:61,621,869...61,633,693

G

B

interferon alpha-2

susceptibility

CTD Direct Evidence: therapeutic
DNA:SNP:exon: p.Ala120Thr (human)

PMID:12802750 PMID:15340535 PMID:15751770 PMID:16246192 PMID:16476009 More...

NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736

G

B

HLA class II histocompatibility antigen, DQ beta 1 chain

no_association
treatment

DNA:SNP: :rs2856718 (human)
DNA:polymorphism: :HLA-DQB1*07(human)
DNA:polymorphisms (human)
DNA:polymorphisms: :multiple

PMID:16237774 PMID:16893387 PMID:28267888 PMID:29287219

RGD:14865012 RGD:14974232 RGD:36049762 RGD:5147637

NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272

G

B

interferon lambda-1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:36,394,462...36,397,363
Ensembl chr19:44,942,186...44,944,519

G

B

class I histocompatibility antigen, Gogo-C*0202 alpha chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,020,373...31,024,959
Ensembl chr 6:31,910,788...31,914,286

G

B

NKG2-A/NKG2-B type II integral membrane protein

severity

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

NCBI chr12:10,469,351...10,576,060
Ensembl chr12:10,720,723...10,744,046

G

B

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
treatment
severity

CTD Direct Evidence: marker/mechanism
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphism: :(human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)
DNA:polymorphisms:multiple (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:SNPs:multiple (human)
DNA:SNP: :rs33054861(human)

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387

G

B

HLA class II histocompatibility antigen, DP alpha 1 chain

susceptibility
treatment
disease_progression

DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)
mRNA:decreased expression:peripheral blood mononuclear cell:
CTD Direct Evidence: marker/mechanism

PMID:19349983 PMID:28275747 PMID:29300980 PMID:30267609

RGD:14694817 RGD:14694818 RGD:14694973

NCBI chr 6:32,637,826...32,646,501
Ensembl chr 6:33,752,638...33,761,417

G

N

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
severity
treatment

DNA:SNP: :rs33054861(human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:SNPs:multiple (human)
DNA:polymorphisms:multiple (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:polymorphism: :(human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663

G

N

HLA class II histocompatibility antigen, DP alpha 1 chain

susceptibility
treatment
disease_progression

DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:peripheral blood mononuclear cell:

PMID:19349983 PMID:28275747 PMID:29300980 PMID:30267609

RGD:14694817 RGD:14694818 RGD:14694973

NCBI chrNW_004624754:23,674,935...23,683,044
Ensembl chrNW_004624754:23,674,448...23,683,662

G

N

HLA class II histocompatibility antigen, DQ beta 1 chain

no_association
treatment

DNA:polymorphisms: :multiple
DNA:SNP: :rs2856718 (human)
DNA:polymorphisms (human)
DNA:polymorphism: :HLA-DQB1*07(human)

PMID:16237774 PMID:16893387 PMID:28267888 PMID:29287219

RGD:14865012 RGD:14974232 RGD:36049762 RGD:5147637

NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713

G

S

HLA class II histocompatibility antigen, DP alpha 1 chain

susceptibility
treatment
disease_progression

DNA:SNP: :rs3077(human)
mRNA:decreased expression:peripheral blood mononuclear cell:
CTD Direct Evidence: marker/mechanism
DNA:polymorphism::HLA-DPA1*04:01(human)

PMID:19349983 PMID:28275747 PMID:29300980 PMID:30267609

RGD:14694817 RGD:14694818 RGD:14694973

NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907

G

S

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
treatment
severity

CTD Direct Evidence: marker/mechanism
DNA:polymorphisms, haplotypes:multiple (human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:polymorphisms:multiple (human)
DNA:polymorphism: :(human)
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:SNPs:multiple (human)
DNA:SNP: :rs33054861(human)

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145

G

S

interleukin-8

severity

mRNA, protein:increased expression:serum, peripheral blood mononuclear cell (human)
associated with liver disease;mRNA, protein:increased expression:liver, blood serum (human)

PMID:23890815 PMID:26265888

RGD:11075958 RGD:150520196

NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353

G

S

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936475:21,841,054...21,845,821

G

C

HLA class II histocompatibility antigen, DP alpha 1 chain

susceptibility
treatment
disease_progression

DNA:SNP: :rs3077(human)
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:peripheral blood mononuclear cell:
DNA:polymorphism::HLA-DPA1*04:01(human)

PMID:19349983 PMID:28275747 PMID:29300980 PMID:30267609

RGD:14694817 RGD:14694818 RGD:14694973

NCBI chrNW_004955437:1,644,037...1,657,094
Ensembl chrNW_004955437:1,643,238...1,651,071

G

C

HLA class II histocompatibility antigen, DP beta 1 chain

susceptibility
treatment
severity

DNA:SNP: :rs33054861(human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphism: :(human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)
DNA:polymorphisms:multiple (human)
DNA:SNPs:multiple (human)
CTD Direct Evidence: marker/mechanism

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chrNW_004955437:1,655,092...1,666,552
Ensembl chrNW_004955437:1,635,538...1,669,042

G

P

interferon lambda-4

severity
disease_progression

DNA:SNP:5'utr: (rs12979860) (human)
DNA:frameshift mutation,substitution:5'utr: p.P70S (rs368234815, rs117648444)

PMID:25740255 PMID:28732143

RGD:40400752 RGD:40886279

NCBI chr 6:47,946,679...47,948,710

G

G

interferon lambda-1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:33,901,382...33,904,356
Ensembl chr 6:33,901,801...33,903,894

G

B

C-C motif chemokine 4

protein:increased expression:blood serum (human)

NCBI chr17:20,689,341...20,691,921

G

D

mannose binding lectin 1

severity

DNA:haplotype: :

NCBI chr 4:29,419,886...29,424,377

G

N

mannose binding lectin 2

severity

DNA:haplotype: :

NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297

G

G

mannose binding lectin 2

severity

DNA:haplotype: :

NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079

G

P

mannose binding lectin 2

severity

DNA:haplotype: :

NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083

G

B

mannose binding lectin 2

severity

DNA:haplotype: :

NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432

G

C

mannose binding lectin 2

severity

DNA:haplotype: :

NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006

G

R

mannose binding lectin 2

severity

DNA:haplotype: :

RGD

NCBI chr 1:228,016,439...228,024,736

G

M

mannose-binding lectin (protein C) 2

severity

DNA:haplotype: :

RGD

NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087

G

H

mannose binding lectin 2

severity

DNA:haplotype: :

RGD

NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784

G

G

major histocompatibility complex, class II, DP alpha 1

susceptibility
treatment
disease_progression

CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:peripheral blood mononuclear cell:
DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)

PMID:19349983 PMID:28275747 PMID:29300980 PMID:30267609

RGD:14694817 RGD:14694818 RGD:14694973

NCBI chr17:39,009,361...39,017,978

G

G

major histocompatibility complex, class II, DP beta 1

treatment
susceptibility
severity

DNA:polymorphism: :(human)
DNA:polymorphisms:multiple (human)
DNA:SNP: :rs33054861(human)
DNA:SNPs:multiple (human)
DNA:SNP:exon 6: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:SNP:exon, 3' utr: (rs9277542) (human)
CTD Direct Evidence: marker/mechanism

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chr17:38,996,329...39,007,097

G

G

major histocompatibility complex, class II, DQ alpha 1

treatment
susceptibility
disease_progression

DNA:polymorphisms: :
DNA:polymorphisms: :HLA-DQA1*0101/2/4, HLA-DQA1*0103 (human)
DNA:polymorphisms: :HLA-DQA1*0303, HLA-DQA1*0505(human)
DNA:haplotype::
DNA:polymorphism: :

PMID:14562382 PMID:15237447 PMID:16883532 PMID:22807686 PMID:27386643 More...

RGD:14398752 RGD:14398755 RGD:14398759 RGD:14398838 RGD:14398840 RGD:14398843

NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871

G

D

microRNA mir-106b

severity

associated with hepatocellular carcinoma;miRNA:increased expression:liver (human)

NCBI chr 6:9,498,558...9,498,616
Ensembl chr 6:9,498,558...9,498,616

G

R

microRNA 106b

severity

associated with hepatocellular carcinoma;miRNA:increased expression:liver (human)

RGD

NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425

G

M

microRNA 106b

severity

associated with hepatocellular carcinoma;miRNA:increased expression:liver (human)

RGD

NCBI chr 5:138,163,999...138,164,080
Ensembl chr 5:138,163,999...138,164,080

G

H

microRNA 106b

severity

associated with hepatocellular carcinoma;miRNA:increased expression:liver (human)

RGD

NCBI chr 7:100,093,993...100,094,074
Ensembl chr 7:100,093,993...100,094,074

G

M

microRNA 146

mRNA:increased expression:T cell (human)

RGD

NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288

G

R

microRNA 146a

mRNA:increased expression:T cell (human)

RGD

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

G

H

microRNA 146a

mRNA:increased expression:T cell (human)

RGD

NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450

G

P

microRNA mir-155

NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902

G

D

microRNA mir-155

NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833

G

R

microRNA 155

RGD

NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718

G

M

microRNA 155

RGD

NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092

G

H

microRNA 155

RGD

NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044

G

P

microRNA mir-885

CTD Direct Evidence: marker/mechanism

NCBI chr13:66,597,531...66,597,610
Ensembl chr13:66,597,531...66,597,610

G

D

microRNA mir-885

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602

G

H

microRNA 885

CTD Direct Evidence: marker/mechanism

NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562

G

N

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chrNW_004624892:2,656,260...2,671,455
Ensembl chrNW_004624892:2,656,260...2,669,946

G

G

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chr20:89,457,549...89,474,756
Ensembl chr20:89,459,493...89,474,352

G

P

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chr 6:167,896,191...167,908,988
Ensembl chr 6:167,896,287...167,908,625

G

S

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chrNW_004936474:24,744,673...24,757,189
Ensembl chrNW_004936474:24,744,673...24,757,085

G

D

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350

G

B

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chr 1:42,639,191...42,654,738
Ensembl chr 1:44,018,395...44,034,492

G

C

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chrNW_004955537:2,922,156...2,937,223
Ensembl chrNW_004955537:2,922,156...2,937,223

G

R

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797

G

M

myeloproliferative leukemia virus oncogene

protein:decreased expression:blood serum (human)

NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710

G

H

MPL proto-oncogene, thrombopoietin receptor

protein:decreased expression:blood serum (human)

RGD

NCBI chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466

G

G

natural cytotoxicity triggering receptor 1

disease_progression
severity

protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)

PMID:26291078 PMID:28328926 PMID:29625837

RGD:39128177 RGD:40400737 RGD:40818237

NCBI chr 6:47,521,488...47,527,713
Ensembl chr 6:47,521,956...47,530,961

G

P

natural cytotoxicity triggering receptor 1

disease_progression
severity

protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

PMID:26291078 PMID:28328926 PMID:29625837

RGD:39128177 RGD:40400737 RGD:40818237

NCBI chr 6:59,092,258...59,099,992
Ensembl chr 6:59,092,911...59,099,990

G

D

natural cytotoxicity triggering receptor 1

severity
disease_progression

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)

PMID:26291078 PMID:28328926 PMID:29625837

RGD:39128177 RGD:40400737 RGD:40818237

NCBI chr 1:102,686,058...102,690,350
Ensembl chr 1:102,686,058...102,690,620

G

B

natural cytotoxicity triggering receptor 1

disease_progression
severity

protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)

PMID:26291078 PMID:28328926 PMID:29625837

RGD:39128177 RGD:40400737 RGD:40818237

NCBI chr19:51,951,496...51,957,433
Ensembl chr19:60,645,677...60,652,274

G

R

natural cytotoxicity triggering receptor 1

severity
disease_progression

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)

RGD

PMID:28328926 PMID:26291078 PMID:29625837

RGD:40400737, RGD:40818237, RGD:39128177

NCBI chr 1:69,614,744...69,622,594
Ensembl chr 1:69,616,601...69,660,558

G

M

natural cytotoxicity triggering receptor 1

severity
disease_progression

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)

RGD

PMID:28328926 PMID:26291078 PMID:29625837

RGD:40400737, RGD:40818237, RGD:39128177

NCBI chr 7:4,340,714...4,348,183
Ensembl chr 7:4,340,723...4,348,163

G

H

natural cytotoxicity triggering receptor 1

severity
disease_progression

protein:increased expression:Peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:peripheral blood mononuclear cell, natural killer cell (human)
protein:decreased expression:Peripheral blood mononuclear cell, natural killer cell (human)

RGD

PMID:28328926 PMID:26291078 PMID:29625837

RGD:40400737, RGD:40818237, RGD:39128177

NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140

G

N

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205

G

G

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

P

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277

G

S

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chrNW_004936494:9,537,793...9,541,187
Ensembl chrNW_004936494:9,537,008...9,541,612

G

D

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433

G

B

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chr14:16,155,331...16,158,588

G

C

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520

G

R

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

RGD

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

M

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

RGD

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

H

NFKB inhibitor alpha

disease_progression

DNA:enhancers: :(rs2233406, rs2233409) (human)

RGD

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

N

programmed cell death 1

disease_progression
no_association

DNA:SNP:exon:
protein:altered expression:serum:
mRNA:increased expression:liver parenchyma (human)
DNA:SNP:3' UTR:rs10204525(human)
DNA:SNPs::+7146 G>A,+7209 C>T(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chrNW_004624847:5,732,922...5,741,908
Ensembl chrNW_004624847:5,732,767...5,742,269

G

G

programmed cell death 1

no_association
disease_progression

DNA:SNPs::+7146 G>A,+7209 C>T(human)
mRNA:increased expression:liver parenchyma (human)
DNA:SNP:exon:
protein:altered expression:serum:
DNA:SNP:3' UTR:rs10204525(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chr10:127,877,383...127,886,234
Ensembl chr10:127,878,554...127,886,088

G

P

programmed cell death 1

disease_progression
no_association

mRNA:increased expression:liver parenchyma (human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNP:3' UTR:rs10204525(human)
DNA:SNPs::+7146 G>A,+7209 C>T(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chr15:140,337,353...140,347,493
Ensembl chr15:140,336,258...140,347,478

G

S

programmed cell death 1

no_association
disease_progression

mRNA:increased expression:liver parenchyma (human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)
DNA:SNP:3' UTR:rs10204525(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chrNW_004936745:152,571...163,712
Ensembl chrNW_004936745:152,612...161,587

G

D

programmed cell death 1

no_association
disease_progression

mRNA:increased expression:liver parenchyma (human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)
DNA:SNP:3' UTR:rs10204525(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723

G

B

programmed cell death 1

disease_progression
no_association

DNA:SNP:3' UTR:rs10204525(human)
protein:altered expression:serum:
mRNA:increased expression:liver parenchyma (human)
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chr12:130,849,353...130,858,776

G

C

programmed cell death 1

no_association
disease_progression

mRNA:increased expression:liver parenchyma (human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)
DNA:SNP:3' UTR:rs10204525(human)

PMID:20700634 PMID:22634051 PMID:25736598 PMID:28983583 PMID:30016557

RGD:36947881 RGD:40818231 RGD:40818233 RGD:40818262 RGD:40818415

NCBI chrNW_004955542:49,290...57,747
Ensembl chrNW_004955542:49,259...58,823

G

R

programmed cell death 1

disease_progression
no_association

DNA:SNP:3' UTR:rs10204525(human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)

RGD

PMID:30016557 PMID:28983583 PMID:20700634 PMID:25736598

RGD:40818231, RGD:40818415, RGD:40818262, RGD:40818233

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

M

programmed cell death 1

disease_progression
no_association

DNA:SNP:3' UTR:rs10204525(human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)

RGD

PMID:30016557 PMID:28983583 PMID:20700634 PMID:25736598

RGD:40818231, RGD:40818415, RGD:40818262, RGD:40818233

NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278

G

H

programmed cell death 1

no_association
disease_progression

mRNA:increased expression:liver parenchyma (human)
protein:altered expression:serum:
DNA:SNP:exon:
DNA:SNPs::+7146 G>A,+7209 C>T(human)
DNA:SNP:3' UTR:rs10204525(human)

RGD

PMID:22634051 PMID:28983583 PMID:20700634 PMID:25736598 PMID:30016557

RGD:36947881, RGD:40818415, RGD:40818262, RGD:40818233, RGD:40818231

NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894

G

N

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chrNW_004624832:5,103,251...5,107,751
Ensembl chrNW_004624832:5,103,072...5,107,801

G

G

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

G

P

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,463

G

S

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chrNW_004936664:2,910,609...2,914,205

G

D

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222

G

B

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003

G

C

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

NCBI chrNW_004955559:1,750,227...1,753,607
Ensembl chrNW_004955559:1,750,168...1,753,629

G

R

protein phosphatase 1, regulatory subunit 15A

mRNA,protein:increased expression:liver

RGD

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

M

protein phosphatase 1, regulatory subunit 15A

mRNA,protein:increased expression:liver

RGD

NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692

G

H

protein phosphatase 1 regulatory subunit 15A

mRNA,protein:increased expression:liver

RGD

NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059

G

P

protein phosphatase 1 regulatory subunit 16A

disease_progression
treatment

PMID:28007350 PMID:29279233

RGD:14975159 RGD:14975240

NCBI chr 4:302,621...320,048
Ensembl chr 4:297,748...320,056

G

N

PR/SET domain 1

disease_progression

NCBI chrNW_004624780:16,205,056...16,227,382
Ensembl chrNW_004624780:16,204,838...16,227,390

G

G

PR/SET domain 1

disease_progression

NCBI chr13:67,695,436...67,719,487
Ensembl chr13:67,695,309...67,718,931

G

P

PR/SET domain 1

disease_progression

NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466

G

S

PR/SET domain 1

disease_progression

NCBI chrNW_004936564:2,594,362...2,690,680
Ensembl chrNW_004936564:2,667,660...2,690,683

G

D

PR/SET domain 1

disease_progression

NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579

G

B

PR/SET domain 1

disease_progression

NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815

G

C

PR/SET domain 1

disease_progression

NCBI chrNW_004955411:31,434,503...31,455,995
Ensembl chrNW_004955411:31,434,503...31,456,056

G

R

PR/SET domain 1

disease_progression

RGD

NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488

G

M

PR domain containing 1, with ZNF domain

disease_progression

RGD

NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497

G

H

PR/SET domain 1

disease_progression

RGD

NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939

G

R

RT1 class II, locus Ba

treatment
susceptibility
disease_progression

DNA:polymorphisms: :
DNA:polymorphisms: :HLA-DQA1*0101/2/4, HLA-DQA1*0103 (human)
DNA:haplotype::
DNA:polymorphisms: :HLA-DQA1*0303, HLA-DQA1*0505(human)
DNA:polymorphism: :

RGD

PMID:27386643 PMID:30168489 PMID:22807686 PMID:16883532 PMID:15237447 More...

RGD:14398752, RGD:14398755, RGD:14398843, RGD:14398840, RGD:14398838, RGD:14398759

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

R

RT1 class II, locus Bb

treatment
no_association

DNA:polymorphisms (human)
DNA:polymorphism: :HLA-DQB1*07(human)
DNA:SNP: :rs2856718 (human)
DNA:polymorphisms: :multiple

RGD

PMID:16893387 PMID:16237774 PMID:28267888 PMID:29287219

RGD:5147637, RGD:36049762, RGD:14974232, RGD:14865012

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

G

R

RT1 class II, locus Db1

disease_progression
susceptibility

DNA:haplotype::
DNA:polymorphisms: :

RGD

PMID:16883532 PMID:16237774

RGD:14398840, RGD:36049762

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

R

RT1 class II, locus Ha

treatment
disease_progression
susceptibility

CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3077(human)
DNA:polymorphism::HLA-DPA1*04:01(human)
mRNA:decreased expression:peripheral blood mononuclear cell:

CTD
RGD

PMID:19349983 PMID:29300980 PMID:28275747 PMID:30267609 PMID:30267609

RGD:14694973, RGD:14694818, RGD:14694817, RGD:14694817

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

G

R

RT1 class II, locus Hb, pseudogene 1

susceptibility
severity
treatment

CTD Direct Evidence: marker/mechanism
DNA:SNP:exon 6: (rs9277542) (human)
DNA:SNPs:multiple (human)
DNA:SNP:exon, 3' utr: (rs9277542) (human)
DNA:polymorphisms, haplotypes:multiple (human)
DNA:polymorphisms:multiple (human)
DNA:polymorphism:exon, 3' utr: (rs9277535) (human)
DNA:SNP: :rs33054861(human)
DNA:polymorphism: :(human)

PMID:19349983 PMID:21274863 PMID:21310144 PMID:22737229 PMID:24520320 More...

RGD:11536957 RGD:14694816 RGD:14974232 RGD:150429660 RGD:150429794 RGD:150429799 RGD:150429802 RGD:150429807 RGD:150429808

NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618

G

P

MHC class I antigen 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:22,938,211...22,942,735

G

N

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chrNW_004624802:11,645,851...11,662,812
Ensembl chrNW_004624802:11,648,020...11,660,216

G

G

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chr11:52,297,890...52,316,089
Ensembl chr11:52,297,543...52,316,105

G

P

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chr 5:21,733,030...21,748,960
Ensembl chr 5:21,733,035...21,751,354

G

S

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chrNW_004936646:747,178...763,449
Ensembl chrNW_004936646:748,727...761,287

G

D

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chr10:641,543...660,882
Ensembl chr10:642,718...658,546

G

B

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chr12:32,555,523...32,574,137
Ensembl chr12:32,808,586...32,827,732

G

C

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

NCBI chrNW_004955458:3,953,019...3,973,151
Ensembl chrNW_004955458:3,952,738...3,970,668

G

R

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

RGD

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

G

M

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

RGD

NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718

G

H

signal transducer and activator of transcription 2

mRNA:decreased expression:monocyte (human)

RGD

NCBI chr12:56,341,597...56,360,107
Ensembl chr12:56,341,597...56,360,203

G

N

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391

G

G

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928

G

P

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chr15:95,656,206...95,764,099
Ensembl chr15:95,656,077...95,763,472

G

S

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chrNW_004936506:7,091,982...7,185,938
Ensembl chrNW_004936506:7,095,009...7,184,689

G

D

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894

G

B

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chr2B:78,331,402...78,549,231
Ensembl chr2B:196,247,881...196,366,011

G

C

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

NCBI chrNW_004955403:8,061,471...8,144,252
Ensembl chrNW_004955403:8,061,471...8,144,276

G

R

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

RGD

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

G

M

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

RGD

NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348

G

H

signal transducer and activator of transcription 4

susceptibility

DNA:SNPs, haplotypes:multiple

RGD

NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,151,596

G

N

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235

G

G

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907

G

P

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198

G

S

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chrNW_004936531:8,555,966...8,562,829
Ensembl chrNW_004936531:8,555,637...8,562,885

G

D

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072

G

B

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chr 5:134,845,689...134,852,938
Ensembl chr 5:140,967,399...140,973,846

G

C

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448

G

R

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

RGD

NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335

G

M

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

RGD

NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607

G

H

stimulator of interferon response cGAMP interactor 1

susceptibility

DNA:hypermethylation:promoter

RGD

NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935

G

N

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chrNW_004624754:23,815,464...23,822,480
Ensembl chrNW_004624754:23,815,915...23,822,827

G

G

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chr17:39,252,000...39,260,195

G

P

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chr 7:25,062,772...25,071,989
Ensembl chr 7:25,062,771...25,074,843

G

S

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chrNW_004936476:25,899,514...25,907,690
Ensembl chrNW_004936476:25,899,339...25,907,695

G

D

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chr12:2,424,049...2,432,165
Ensembl chr12:2,378,126...2,432,303

G

B

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chr 6:32,414,665...32,423,488
Ensembl chr 6:33,530,171...33,538,978

G

C

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

NCBI chrNW_004955437:1,504,549...1,511,110
Ensembl chrNW_004955437:1,504,947...1,511,097

G

R

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

RGD

NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901

G

M

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

mRNA:decreased expression:blood

RGD

NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199

G

H

transporter 1, ATP binding cassette subfamily B member

mRNA:decreased expression:blood

RGD

NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816

G

N

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chrNW_004624751:624,569...647,198

G

G

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

P

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421

G

S

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697

G

D

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951

G

B

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

Ensembl chr 5:1,300,960...1,338,872

G

C

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

NCBI chrNW_004955504:649,248...669,796
Ensembl chrNW_004955504:651,779...670,589

G

R

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

RGD

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

M

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

RGD

NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962

G

H

telomerase reverse transcriptase

susceptibility

DNA:SNP, haplotype: :rs10069690,rs2242652(human)

RGD

NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068

G

N

transforming growth factor beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605

G

G

transforming growth factor beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

G

P

transforming growth factor beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046

G

S

transforming growth factor beta 1

no_association

DNA:SNPs:promoter:-509C>T (rs1800469) (human)
DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)

NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272

G

B

transforming growth factor beta 1

no_association

DNA:SNPs:promoter:-509C>T (rs1800469) (human)
DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

G

C

transforming growth factor beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441

G

R

transforming growth factor, beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

RGD

PMID:28700046 PMID:28700046

RGD:14995436, RGD:14995436

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

M

transforming growth factor, beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

RGD

PMID:28700046 PMID:28700046

RGD:14995436, RGD:14995436

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

G

H

transforming growth factor beta 1

no_association

DNA:SNPs, haplotypes: :869C>T (rs1800470), 11929C>T (rs1800472) (human)
DNA:SNPs:promoter:-509C>T (rs1800469) (human)

RGD

PMID:28700046 PMID:28700046

RGD:14995436, RGD:14995436

NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922

G

N

toll like receptor 2

treatment
disease_progression

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833

G

G

toll like receptor 2

disease_progression
treatment

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795

G

P

toll like receptor 2

treatment
disease_progression

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330

G

S

toll like receptor 2

treatment
disease_progression

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788

G

D

toll like receptor 2

disease_progression
treatment

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241

G

B

toll like receptor 2

disease_progression
treatment

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331

G

C

toll like receptor 2

disease_progression
treatment

protein:increased expression:serum:

PMID:25337250 PMID:25771704 PMID:28414577

RGD:15090812 RGD:15090826 RGD:15090828

NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258

G

R

toll-like receptor 2

treatment
disease_progression

protein:increased expression:serum:

RGD

PMID:28414577 PMID:25771704 PMID:25337250

RGD:15090812, RGD:15090828, RGD:15090826

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

M

toll-like receptor 2

treatment
disease_progression

protein:increased expression:serum:

RGD

PMID:28414577 PMID:25771704 PMID:25337250

RGD:15090812, RGD:15090828, RGD:15090826

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

G

H

toll like receptor 2

treatment
disease_progression

protein:increased expression:serum:

RGD

PMID:28414577 PMID:25771704 PMID:25337250

RGD:15090812, RGD:15090828, RGD:15090826

NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260

G

N

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196

G

G

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232

G

P

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291

G

S

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907

G

D

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247

G

B

toll like receptor 3

susceptibility

DNA:snp: :rs3775290(human)
DNA:SNP, haplotype: :1234C>T (human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728

G

C

toll like receptor 3

susceptibility

DNA:SNP, haplotype: :1234C>T (human)
DNA:snp: :rs3775290(human)

PMID:23076446 PMID:26024592

RGD:21079416 RGD:21079425

NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467

G

R

toll-like receptor 3

susceptibility

DNA:snp: :rs3775290(human)
DNA:SNP, haplotype: :1234C>T (human)

RGD

PMID:26024592 PMID:23076446

RGD:21079416, RGD:21079425

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

G

M

toll-like receptor 3

susceptibility

DNA:snp: :rs3775290(human)
DNA:SNP, haplotype: :1234C>T (human)

RGD

PMID:26024592 PMID:23076446

RGD:21079416, RGD:21079425

NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117

G

H

toll like receptor 3

susceptibility

DNA:snp: :rs3775290(human)
DNA:SNP, haplotype: :1234C>T (human)

RGD

PMID:26024592 PMID:23076446

RGD:21079416, RGD:21079425

NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073

G

N

toll like receptor 4

protein:increased expression:serum:

NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120

G

G

toll like receptor 4

protein:increased expression:serum:

NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515

G

P

toll like receptor 4

protein:increased expression:serum:

NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970

G

S

toll like receptor 4

protein:increased expression:serum:

NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095

G

D

toll like receptor 4

protein:increased expression:serum:

NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165

G

B

toll like receptor 4

protein:increased expression:serum:

NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711

G

C

toll like receptor 4

protein:increased expression:serum:

NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135

G

R

toll-like receptor 4

protein:increased expression:serum:

RGD

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

M

toll-like receptor 4

protein:increased expression:serum:

RGD

NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521

G

H

toll like receptor 4

protein:increased expression:serum:

RGD

NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735

G

P

toll like receptor 9

severity

DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)
mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
protein:increased expression:peripheral blood mononuclear cell (human)
mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
protein: increased expression:peripheral blood mononuclear cell (human)

PMID:18215354 PMID:19513613 PMID:24622882 PMID:27126946 PMID:30453064

RGD:18337464 RGD:18337467 RGD:18337470 RGD:18337472 RGD:18337474

NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673

G

D

toll like receptor 9

severity

mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
protein: increased expression:peripheral blood mononuclear cell (human)
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)

PMID:18215354 PMID:19513613 PMID:24622882 PMID:27126946 PMID:30453064

RGD:18337464 RGD:18337467 RGD:18337470 RGD:18337472 RGD:18337474

NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114

G

C

toll like receptor 9

severity

mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
protein:increased expression:peripheral blood mononuclear cell (human)
protein: increased expression:peripheral blood mononuclear cell (human)
DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)

PMID:18215354 PMID:19513613 PMID:24622882 PMID:27126946 PMID:30453064

RGD:18337464 RGD:18337467 RGD:18337470 RGD:18337472 RGD:18337474

NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582

G

R

toll-like receptor 9

severity

mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
protein:increased expression:peripheral blood mononuclear cell (human)
protein: increased expression:peripheral blood mononuclear cell (human)
mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)

RGD

PMID:24622882 PMID:27126946 PMID:18215354 PMID:19513613 PMID:30453064

RGD:18337464, RGD:18337474, RGD:18337472, RGD:18337470, RGD:18337467

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

G

M

toll-like receptor 9

severity

mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
protein:increased expression:peripheral blood mononuclear cell (human)
protein: increased expression:peripheral blood mononuclear cell (human)
mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)

RGD

PMID:24622882 PMID:27126946 PMID:18215354 PMID:19513613 PMID:30453064

RGD:18337464, RGD:18337474, RGD:18337472, RGD:18337470, RGD:18337467

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

G

H

toll like receptor 9

severity

mRNA, protein: decreased expression:liver, CD14-positive monocyte (human)
protein:increased expression:peripheral blood mononuclear cell (human)
protein: increased expression:peripheral blood mononuclear cell (human)
mRNA, protein:decreased expression:peripheral blood mononuclear cell (human)
DNA:SNPs: 5'UTR: (rs5743836, rs187084) (human)

RGD

PMID:24622882 PMID:27126946 PMID:18215354 PMID:19513613 PMID:30453064

RGD:18337464, RGD:18337474, RGD:18337472, RGD:18337470, RGD:18337467

NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645

G

G

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197

G

P

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822

G

S

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345

G

D

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001

G

B

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819

G

C

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469

G

R

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

RGD

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

G

M

tumor necrosis factor, alpha-induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

RGD

NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405

G

H

TNF alpha induced protein 3

susceptibility

DNA:SNP,haplotypes: (rs148314165, rs200820567) (human)

RGD

NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314

G

N

TNF superfamily member 13b

treatment

NCBI chrNW_004624793:3,629,425...3,664,258

G

G

TNF superfamily member 13b

treatment

NCBI chr 3:86,637,988...86,675,774
Ensembl chr 3:86,638,302...86,675,772

G

P

TNF superfamily member 13b

treatment

NCBI chr11:75,599,296...75,633,044
Ensembl chr11:75,599,598...75,633,041

G

S

TNF superfamily member 13b

treatment

NCBI chrNW_004936472:3,789,111...3,834,163
Ensembl chrNW_004936472:3,788,095...3,822,148

G

D

TNF superfamily member 13b

treatment

NCBI chr22:57,036,307...57,069,053
Ensembl chr22:57,036,292...57,068,320

G

B

TNF superfamily member 13b

treatment

NCBI chr13:89,399,044...89,438,837
Ensembl chr13:108,536,617...108,574,296

G

C

TNF superfamily member 13b

treatment

NCBI chrNW_004955404:3,536,041...3,573,242
Ensembl chrNW_004955404:3,536,868...3,569,750

G

R

TNF superfamily member 13b

treatment

RGD

NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693

G

M

tumor necrosis factor (ligand) superfamily, member 13b

treatment

RGD

NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072

G

H

TNF superfamily member 13b

treatment

RGD

NCBI chr13:108,269,629...108,308,484
Ensembl chr13:108,251,240...108,308,484

G

N

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004624747:1,125,009...1,178,595
Ensembl chrNW_004624747:1,125,022...1,177,524

G

G

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chr19:4,485,960...4,538,838

G

P

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chr14:50,265,102...50,315,409

G

S

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004936619:2,070,836...2,137,314
Ensembl chrNW_004936619:2,070,731...2,137,369

G

D

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chr26:30,835,222...30,899,842
Ensembl chr26:30,823,209...30,898,324

G

B

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chr22:3,690,100...3,746,665
Ensembl chr22:20,174,546...20,229,928

G

C

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chrNW_004955442:17,487,815...17,581,675
Ensembl chrNW_004955442:17,487,815...17,581,675

G

R

ubiquitin-conjugating enzyme E2L 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862

G

M

ubiquitin-conjugating enzyme E2L 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:16,969,879...17,019,363
Ensembl chr16:16,969,877...17,020,513

G

H

ubiquitin conjugating enzyme E2 L3

CTD Direct Evidence: marker/mechanism

NCBI chr22:21,549,447...21,624,034
Ensembl chr22:21,549,447...21,624,034

G

N

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chrNW_004624746:15,094,890...15,330,653
Ensembl chrNW_004624746:15,098,960...15,254,127

G

G

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

G

P

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chr 6:15,693,987...15,941,301
Ensembl chr 6:15,698,199...15,863,270

G

S

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chrNW_004936475:21,005,242...21,235,992
Ensembl chrNW_004936475:21,080,302...21,231,544

G

D

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chr 5:78,450,963...78,635,615
Ensembl chr 5:78,455,005...78,610,033

G

B

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chr16:51,936,471...52,209,695
Ensembl chr16:72,635,666...72,808,360

G

C

zinc finger homeobox 3

protein:increased expression:blood serum (human)

NCBI chrNW_004955484:5,470,203...5,746,325
Ensembl chrNW_004955484:5,474,769...5,789,707

G

R

zinc finger homeobox 3

protein:increased expression:blood serum (human)

RGD

NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771

G

M

zinc finger homeobox 3

protein:increased expression:blood serum (human)

RGD

NCBI chr 8:109,005,975...109,688,272
Ensembl chr 8:108,669,276...109,688,262

G

H

zinc finger homeobox 3

protein:increased expression:blood serum (human)

RGD

NCBI chr16:72,782,885...73,891,930
Ensembl chr16:72,782,885...73,891,871

Term paths to the root

Path 1
Term	Annotations
disease	199766
disease by infectious agent	21384
viral infectious disease	16237
DNA Virus Infections	2727
Hepadnaviridae Infections	1114
hepatitis B	1114
Chronic Hepatitis B	605
Path 2
Term	Annotations
disease	199766
disease of anatomical entity	168031
gastrointestinal system disease	65643
hepatobiliary disease	28572
liver disease	27505
hepatitis	2601
viral hepatitis	1799
Human Viral Hepatitis	1778
hepatitis B	1114
Chronic Hepatitis B	605

paths to the root