Il21 (interleukin 21) - Rat Genome Database

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Gene: Il21 (interleukin 21) Mus musculus
Analyze
Symbol: Il21
Name: interleukin 21
RGD ID: 1316554
MGI Page MGI
Description: Enables cytokine receptor binding activity. Involved in cellular response to virus; lymphocyte activation involved in immune response; and positive regulation of immunoglobulin production. Acts upstream of or within positive regulation of cytokine production; positive regulation of natural killer cell differentiation; and positive regulation of natural killer cell mediated cytotoxicity. Predicted to be located in extracellular space. Is expressed in ductus deferens; epididymis; and testis. Human ortholog(s) of this gene implicated in asthma; common variable immunodeficiency; hepatocellular carcinoma; and systemic lupus erythematosus. Orthologous to human IL21 (interleukin 21); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; alpha-hexylcinnamaldehyde; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-21; interleukin-21
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39337,276,908 - 37,286,785 (-)NCBIGRCm39mm39
GRCm39 Ensembl337,276,908 - 37,286,785 (-)Ensembl
GRCm38337,222,759 - 37,232,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl337,222,759 - 37,232,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37337,121,681 - 37,131,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv36337,107,141 - 37,117,000 (-)NCBImm8
MGSCv36337,414,308 - 37,424,167 (-)NCBImm8
Celera337,106,874 - 37,116,609 (-)NCBICelera
Cytogenetic Map3BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Abe K, etal., Springerplus. 2016 Jun 18;5(1):777. doi: 10.1186/s40064-016-2512-y. eCollection 2016.
2. Abu El-Hamd M, etal., Dermatol Ther. 2019 Sep;32(5):e13063. doi: 10.1111/dth.13063. Epub 2019 Aug 29.
3. Andersson A, etal., PLoS One. 2008;3(11):e3682. Epub 2008 Nov 10.
4. Bobbala D, etal., Cytokine. 2016 Sep;85:83-91. doi: 10.1016/j.cyto.2016.06.011. Epub 2016 Jun 11.
5. Caruso R, etal., J Immunol. 2007 May 1;178(9):5957-65. doi: 10.4049/jimmunol.178.9.5957.
6. Chatterjee R, etal., Int Arch Allergy Immunol. 2009;148(2):137-46. Epub 2008 Sep 19.
7. Einarsdottir E, etal., Tissue Antigens. 2011 Dec;78(6):428-37. doi: 10.1111/j.1399-0039.2011.01791.x.
8. Eto D, etal., PLoS One. 2011 Mar 14;6(3):e17739. doi: 10.1371/journal.pone.0017739.
9. Feng G, etal., Mol Cells. 2013 Oct;36(4):362-7. doi: 10.1007/s10059-013-0181-z. Epub 2013 Oct 22.
10. Gibson-Corley KN, etal., Am J Pathol. 2012 May;180(5):2009-17. doi: 10.1016/j.ajpath.2012.01.012. Epub 2012 Mar 17.
11. Hanari N, etal., Anticancer Res. 2007 Jul-Aug;27(4B):2305-10.
12. He X, etal., Immunol Res. 2012 Jun;52(3):240-9. doi: 10.1007/s12026-012-8332-4.
13. Hejr S, etal., Viral Immunol. 2013 Jun;26(3):201-6. doi: 10.1089/vim.2013.0007. Epub 2013 May 8.
14. Hiromura Y, etal., J Immunol. 2007 Nov 15;179(10):7157-65.
15. Holm C, etal., Cytokine. 2006 Jan 7;33(1):41-5. doi: 10.1016/j.cyto.2005.11.014. Epub 2006 Jan 5.
16. Hu K, etal., Immunol Invest. 2011;40(3):265-78. doi: 10.3109/08820139.2010.534219. Epub 2011 Jan 4.
17. Hu X, etal., J Viral Hepat. 2011 Jul;18(7):458-67. doi: 10.1111/j.1365-2893.2011.01475.x. Epub 2011 Jun 1.
18. Kratholm SK, etal., PLoS One. 2013 Dec 16;8(12):e81790. doi: 10.1371/journal.pone.0081790. eCollection 2013.
19. Leng RX, etal., PLoS One. 2012;7(12):e51090. doi: 10.1371/journal.pone.0051090. Epub 2012 Dec 7.
20. Li J, etal., J Interferon Cytokine Res. 2015 Feb;35(2):134-42. doi: 10.1089/jir.2013.0119. Epub 2014 Sep 22.
21. Li N, etal., Hum Immunol. 2013 May;74(5):567-73. doi: 10.1016/j.humimm.2013.01.005. Epub 2013 Jan 24.
22. Li Y, etal., Mol Oral Microbiol. 2010 Aug;25(4):275-92.
23. Liu X, etal., J Interferon Cytokine Res. 2016 Jun;36(6):367-73. doi: 10.1089/jir.2015.0129. Epub 2016 Feb 3.
24. MGD data from the GO Consortium
25. MGD IEA
26. Moretto MM and Khan IA, J Immunol. 2016 Jan 1;196(1):375-84. doi: 10.4049/jimmunol.1501258. Epub 2015 Nov 23.
27. OMIM Disease Annotation Pipeline
28. Pan Q, etal., J Viral Hepat. 2014;21(9):e78-88. doi: 10.1111/jvh.12242. Epub 2014 Mar 10.
29. Pipeline to import KEGG annotations from KEGG into RGD
30. Pérez-Mazliah D, etal., PLoS Pathog. 2015 Mar 12;11(3):e1004715. doi: 10.1371/journal.ppat.1004715. eCollection 2015 Mar.
31. Rajaei T, etal., Med Microbiol Immunol. 2017 Jun;206(3):195-201. doi: 10.1007/s00430-017-0492-3. Epub 2017 Apr 4.
32. Ren G, etal., AIDS. 2012 Nov 13;26(17):2145-53. doi: 10.1097/QAD.0b013e328359b7ae.
33. RGD automated import pipeline
34. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. RGD automated import pipeline for gene-chemical interactions
36. Rodrigues L, etal., Mol Immunol. 2009 Apr;46(7):1494-504. doi: 10.1016/j.molimm.2008.12.033. Epub 2009 Feb 23.
37. Rydén AK, etal., J Autoimmun. 2017 Nov;84:65-74. doi: 10.1016/j.jaut.2017.07.006. Epub 2017 Jul 12.
38. Shen Z, etal., Theranostics. 2019 May 31;9(13):3798-3811. doi: 10.7150/thno.35331. eCollection 2019.
39. Shen Z, etal., Theranostics. 2020 Apr 25;10(12):5600-5612. doi: 10.7150/thno.44715. eCollection 2020.
40. Spolski R, etal., J Immunol. 2012 Feb 15;188(4):1924-32. Epub 2012 Jan 11.
41. Stumhofer JS, etal., PLoS One. 2013 May 7;8(5):e62889. doi: 10.1371/journal.pone.0062889. Print 2013.
42. Sun Z, etal., J Tradit Chin Med. 2020 Feb;40(1):38-48.
43. Tang L, etal., J Infect Dis. 2019 Feb 15;219(5):750-759. doi: 10.1093/infdis/jiy576.
44. Tang R, etal., Immunotherapy. 2018 Mar;10(3):189-200. doi: 10.2217/imt-2017-0060.
45. Vivanco-Cid H, etal., Immunol Lett. 2014 Sep;161(1):89-95. doi: 10.1016/j.imlet.2014.05.006. Epub 2014 May 22.
46. Vyas AK, etal., Liver Int. 2018 Jan;38(1):38-49. doi: 10.1111/liv.13475. Epub 2017 Jun 1.
47. Wang X, etal., Gastroenterology. 2018 Jun;154(8):2222-2236. doi: 10.1053/j.gastro.2018.03.021. Epub 2018 Mar 12.
48. Wang X, etal., Medicine (Baltimore). 2018 Jun;97(23):e10891. doi: 10.1097/MD.0000000000010891.
49. Wu A, etal., Can J Neurol Sci. 2012 Nov;39(6):813-20. doi: 10.1017/s0317167100015663.
50. Yang F, etal., Virol J. 2015 Feb 11;12:20. doi: 10.1186/s12985-015-0257-9.
51. Yao JY, etal., World J Gastroenterol. 2015 Apr 14;21(14):4232-9. doi: 10.3748/wjg.v21.i14.4232.
52. Yasmin S, etal., Infect Immun. 2019 Oct 18;87(11). pii: IAI.00237-19. doi: 10.1128/IAI.00237-19. Print 2019 Nov.
53. Ye X, etal., Cancer Prev Res (Phila). 2017 Jul;10(7):398-409. doi: 10.1158/1940-6207.CAPR-16-0178. Epub 2017 May 8.
54. Yoo JK and Braciale TJ, PLoS One. 2014 Sep 24;9(9):e105872. doi: 10.1371/journal.pone.0105872. eCollection 2014.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11081504   PMID:11217851   PMID:11970879   PMID:12370258   PMID:12393685   PMID:12446913   PMID:12466851   PMID:12477932   PMID:12682241  
PMID:12847225   PMID:12893770   PMID:14502230   PMID:14675186   PMID:14679059   PMID:14734732   PMID:14764669   PMID:15100251   PMID:15240677   PMID:15494482   PMID:15585879   PMID:15684054  
PMID:15728477   PMID:15879595   PMID:16141072   PMID:16141073   PMID:16600195   PMID:16778988   PMID:16785504   PMID:16785506   PMID:16943384   PMID:16951332   PMID:16979605   PMID:17178921  
PMID:17312126   PMID:17339481   PMID:17509926   PMID:17532053   PMID:17548600   PMID:17554014   PMID:17581588   PMID:17581589   PMID:17673207   PMID:17884812   PMID:17918200   PMID:17918202  
PMID:17938255   PMID:18052963   PMID:18056403   PMID:18276844   PMID:18390721   PMID:18395085   PMID:18413772   PMID:18474630   PMID:18490706   PMID:18515660   PMID:18546146   PMID:18585065  
PMID:18599325   PMID:18602282   PMID:18656702   PMID:18773086   PMID:18981236   PMID:19020307   PMID:19050256   PMID:19062315   PMID:19073938   PMID:19088203   PMID:19098919   PMID:19139170  
PMID:19168593   PMID:19208913   PMID:19221396   PMID:19234181   PMID:19265120   PMID:19342640   PMID:19443735   PMID:19570826   PMID:19592651   PMID:19718060   PMID:19797314   PMID:19841075  
PMID:19843883   PMID:19880748   PMID:19915059   PMID:20042469   PMID:20057909   PMID:20061408   PMID:20064451   PMID:20101507   PMID:20131264   PMID:20142429   PMID:20142430   PMID:20303179  
PMID:20368279   PMID:20465570   PMID:20519643   PMID:20574002   PMID:20639489   PMID:20660710   PMID:20826721   PMID:20844201   PMID:20926797   PMID:20974986   PMID:21061439   PMID:21098093  
PMID:21257966   PMID:21258423   PMID:21267068   PMID:21270405   PMID:21357471   PMID:21393863   PMID:21430227   PMID:21441456   PMID:21505191   PMID:21511186   PMID:21593413   PMID:21873635  
PMID:21911600   PMID:21949017   PMID:21987656   PMID:22013017   PMID:22019586   PMID:22118527   PMID:22120117   PMID:22120118   PMID:22205023   PMID:22231702   PMID:22365664   PMID:22370718  
PMID:22442347   PMID:22466669   PMID:22552227   PMID:22643047   PMID:22665806   PMID:22723520   PMID:22781775   PMID:22829452   PMID:23045607   PMID:23064231   PMID:23098768   PMID:23168836  
PMID:23169140   PMID:23200827   PMID:23281399   PMID:23312859   PMID:23437182   PMID:23447690   PMID:23453633   PMID:23516660   PMID:23557800   PMID:23607664   PMID:23637417   PMID:23696736  
PMID:23825648   PMID:23858031   PMID:23960240   PMID:23992866   PMID:24078696   PMID:24194600   PMID:24350772   PMID:24357415   PMID:24416451   PMID:24430438   PMID:24446516   PMID:24470500  
PMID:24508410   PMID:24550509   PMID:24572790   PMID:24616379   PMID:24820310   PMID:24973819   PMID:25053783   PMID:25073789   PMID:25092334   PMID:25170154   PMID:25246268   PMID:25339665  
PMID:25351608   PMID:25545680   PMID:25586558   PMID:26170288   PMID:26194763   PMID:26287681   PMID:26363366   PMID:26410627   PMID:26413871   PMID:26491200   PMID:26499265   PMID:26519529  
PMID:26527008   PMID:26792801   PMID:26826252   PMID:27062692   PMID:27067007   PMID:27118610   PMID:27487330   PMID:27554052   PMID:27571893   PMID:27573866   PMID:27670591   PMID:27798619  
PMID:27819295   PMID:27924822   PMID:28057742   PMID:28294304   PMID:28303891   PMID:28351982   PMID:28405614   PMID:28583714   PMID:28798332   PMID:28875978   PMID:28978474   PMID:29192177  
PMID:29220875   PMID:29242561   PMID:29483597   PMID:29549115   PMID:29563177   PMID:29844233   PMID:29925696   PMID:30144035   PMID:30446568   PMID:30478091   PMID:30654048   PMID:31019062  
PMID:31132747   PMID:31276232   PMID:31356165   PMID:31356706   PMID:31412245   PMID:31467912   PMID:31491724   PMID:31756235   PMID:31940277   PMID:32122993   PMID:32130409   PMID:32271164  
PMID:32493841   PMID:32680956   PMID:32855360   PMID:32859726   PMID:33916486   PMID:34158852  


Genomics

Comparative Map Data
Il21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39337,276,908 - 37,286,785 (-)NCBIGRCm39mm39
GRCm39 Ensembl337,276,908 - 37,286,785 (-)Ensembl
GRCm38337,222,759 - 37,232,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl337,222,759 - 37,232,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37337,121,681 - 37,131,540 (-)NCBIGRCm37mm9NCBIm37
MGSCv36337,107,141 - 37,117,000 (-)NCBImm8
MGSCv36337,414,308 - 37,424,167 (-)NCBImm8
Celera337,106,874 - 37,116,609 (-)NCBICelera
Cytogenetic Map3BNCBI
IL21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4122,610,108 - 122,621,066 (-)EnsemblGRCh38hg38GRCh38
GRCh384122,610,108 - 122,621,066 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374123,531,263 - 123,542,221 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364123,739,272 - 123,761,662 (-)NCBINCBI36hg18NCBI36
Build 344123,891,388 - 123,899,817NCBI
Celera4120,916,832 - 120,925,261 (-)NCBI
Cytogenetic Map4q27NCBI
HuRef4119,260,228 - 119,268,550 (-)NCBIHuRef
CHM1_14123,510,250 - 123,518,679 (-)NCBICHM1_1
Il21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22120,119,598 - 120,126,941 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2120,119,444 - 120,126,996 (-)Ensembl
Rnor_6.02123,965,021 - 123,972,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2123,965,021 - 123,972,356 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02143,573,215 - 143,580,530 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42123,774,331 - 123,781,697 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12123,697,822 - 123,750,231 (-)NCBI
Celera2115,067,969 - 115,075,326 (-)NCBICelera
Cytogenetic Map2q25NCBI
Il21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542818,057,096 - 18,065,492 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542818,057,096 - 18,065,492 (+)NCBIChiLan1.0ChiLan1.0
IL21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14125,940,979 - 125,951,915 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4125,943,495 - 125,951,915 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04114,795,979 - 114,806,936 (-)NCBIMhudiblu_PPA_v0panPan3
IL21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11917,641,833 - 17,651,275 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1917,641,833 - 17,651,266 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1917,860,011 - 17,869,452 (+)NCBI
ROS_Cfam_1.01917,760,158 - 17,769,609 (+)NCBI
UMICH_Zoey_3.11917,712,780 - 17,722,226 (+)NCBI
UNSW_CanFamBas_1.01917,993,018 - 18,002,469 (+)NCBI
UU_Cfam_GSD_1.01918,463,313 - 18,472,753 (+)NCBI
Il21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530165,422,896 - 65,429,900 (+)NCBI
SpeTri2.0NW_0049366621,689,879 - 1,696,883 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8101,530,949 - 101,540,738 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18101,532,742 - 101,540,712 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28108,688,772 - 108,696,742 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1769,859,793 - 69,872,237 (-)NCBI
ChlSab1.1 Ensembl769,863,535 - 69,872,025 (-)Ensembl
Vero_WHO_p1.0NW_02366603748,822,863 - 48,834,392 (-)NCBI
Il21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247773,054,368 - 3,061,304 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3447125538471355Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31157630445576442Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1823401952234019Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32012071354125954Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33188340565883548Mouse
12910778Pwgrq13_mpost-weaning growth rate QTL 13 (mouse)33258161158109942Mouse
12910781Pwgrq12_mpost-weaning growth rate QTL 12 (mouse)33258161158109942Mouse
1357689Mdmsc1_mmodifier of muscularity 1 (mouse)Not determined33327305245962044Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33358101667581166Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33384462467844807Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33384462467844807Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33426332068263320Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33466868268668682Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33550000069500000Mouse
14746977Manh53_mmandible shape 53 (mouse)33601785970017859Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337120713143647422Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33712559368809613Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:868
Count of miRNA genes:529
Interacting mature miRNAs:628
Transcripts:ENSMUST00000029273, ENSMUST00000161015
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000029273   ⟹   ENSMUSP00000029273
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl337,276,908 - 37,286,767 (-)Ensembl
GRCm38.p6 Ensembl337,222,759 - 37,232,618 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161015   ⟹   ENSMUSP00000124668
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl337,279,486 - 37,286,714 (-)Ensembl
GRCm38.p6 Ensembl337,225,337 - 37,232,565 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196943
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl337,284,451 - 37,286,785 (-)Ensembl
GRCm38.p6 Ensembl337,230,302 - 37,232,636 (-)Ensembl
RefSeq Acc Id: NM_001291041   ⟹   NP_001277970
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39337,276,908 - 37,286,785 (-)NCBI
GRCm38337,222,759 - 37,232,636 (-)NCBI
Celera337,106,874 - 37,116,627 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021782   ⟹   NP_068554
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39337,276,908 - 37,286,785 (-)NCBI
GRCm38337,222,759 - 37,232,636 (-)NCBI
MGSCv37337,121,681 - 37,131,540 (-)RGD
Celera337,106,874 - 37,116,627 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_068554   ⟸   NM_021782
- Peptide Label: isoform 2 precursor
- UniProtKB: Q9ES17 (UniProtKB/Swiss-Prot),   Q5SUE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277970   ⟸   NM_001291041
- Peptide Label: isoform 1 precursor
- UniProtKB: E9PX58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029273   ⟸   ENSMUST00000029273
RefSeq Acc Id: ENSMUSP00000124668   ⟸   ENSMUST00000161015

Promoters
RGD ID:6880512
Promoter ID:EPDNEW_M3707
Type:single initiation site
Name:Il21_1
Description:Mus musculus interleukin 21 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38337,232,636 - 37,232,696EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1890474 AgrOrtholog
Ensembl Genes ENSMUSG00000027718 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000029273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124668 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000161015 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-15/IL-21_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-15/IL-21_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:60505 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1890474 ENTREZGENE
NCBI Gene 60505 ENTREZGENE
PANTHER PTHR14356 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il21 PhenoGen
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A5J0L5_MOUSE UniProtKB/TrEMBL
  E9PX58 ENTREZGENE, UniProtKB/TrEMBL
  IL21_MOUSE UniProtKB/Swiss-Prot
  Q5SUE2 ENTREZGENE, UniProtKB/TrEMBL
  Q9ES17 ENTREZGENE