FBXO11 (F-box protein 11) - Rat Genome Database

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Gene: FBXO11 (F-box protein 11) Canis lupus familiaris
Analyze
Symbol: FBXO11
Name: F-box protein 11
RGD ID: 12125499
Description: ENCODES a protein that exhibits metal ion binding (inferred); protein-arginine N-methyltransferase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); positive regulation of protein catabolic process (ortholog); sensory perception of sound (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH breast carcinoma (ortholog); Developmental Disease (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11049,838,003 - 49,864,211 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1049,838,776 - 49,925,064 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1049,693,555 - 49,780,653 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01050,711,840 - 50,799,252 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1050,711,894 - 50,799,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11050,419,057 - 50,506,412 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01050,705,887 - 50,793,282 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01050,893,652 - 50,980,961 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FBXO11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11049,838,003 - 49,864,211 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1049,838,776 - 49,925,064 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1049,693,555 - 49,780,653 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01050,711,840 - 50,799,252 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1050,711,894 - 50,799,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11050,419,057 - 50,506,412 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01050,705,887 - 50,793,282 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01050,893,652 - 50,980,961 (-)NCBIUU_Cfam_GSD_1.0
FBXO11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38247,806,920 - 47,906,498 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl247,789,316 - 47,906,498 (-)EnsemblGRCh38hg38GRCh38
GRCh37248,034,059 - 48,133,637 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36247,887,563 - 47,986,318 (-)NCBINCBI36Build 36hg18NCBI36
Build 34247,957,375 - 48,044,465NCBI
Celera247,873,581 - 47,972,357 (-)NCBICelera
Cytogenetic Map2p16.3NCBI
HuRef247,770,542 - 47,869,544 (-)NCBIHuRef
CHM1_1247,964,454 - 48,063,258 (-)NCBICHM1_1
T2T-CHM13v2.0247,812,869 - 47,912,466 (-)NCBIT2T-CHM13v2.0
Fbxo11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391788,298,287 - 88,373,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1788,298,287 - 88,372,719 (-)EnsemblGRCm39 Ensembl
GRCm381787,990,859 - 88,066,045 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,990,859 - 88,065,291 (-)EnsemblGRCm38mm10GRCm38
MGSCv371788,390,199 - 88,464,625 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361787,899,185 - 87,973,611 (-)NCBIMGSCv36mm8
Celera1792,401,160 - 92,425,975 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1757.87NCBI
Fbxo11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8612,240,348 - 12,316,223 (+)NCBIGRCr8
mRatBN7.266,486,761 - 6,562,664 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl66,486,015 - 6,562,662 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx66,820,525 - 6,844,805 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.067,129,930 - 7,154,210 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.066,657,075 - 6,681,355 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0611,662,356 - 11,737,427 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl611,662,356 - 11,686,682 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0621,634,305 - 21,709,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0621,398,929 - 21,414,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4611,542,561 - 11,566,829 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1611,542,560 - 11,566,829 (-)NCBI
Celera66,301,914 - 6,326,193 (+)NCBICelera
Cytogenetic Map6q12NCBI
Fbxo11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544114,471,283 - 14,553,916 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544114,471,283 - 14,495,508 (-)NCBIChiLan1.0ChiLan1.0
FBXO11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21278,478,591 - 78,577,716 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A78,482,579 - 78,582,236 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A47,926,629 - 48,026,245 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A48,849,746 - 48,948,007 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A48,830,780 - 48,886,300 (-)Ensemblpanpan1.1panPan2
Fbxo11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629233,194,074 - 33,280,085 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365084,685,595 - 4,708,694 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365084,622,695 - 4,708,694 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl392,696,441 - 92,792,616 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1392,696,402 - 92,792,623 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2398,680,348 - 98,710,235 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11459,276,380 - 59,375,635 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1459,276,447 - 59,374,442 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604552,468,631 - 52,568,736 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473829,108,809 - 29,191,368 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473829,108,759 - 29,190,725 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FBXO11
202 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 4 22 6 6 6 6 1 12 8 10 6
Low 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000004211   ⟹   ENSCAFP00000003895
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1049,838,776 - 49,920,924 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074063   ⟹   ENSCAFP00000055077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1049,838,776 - 49,925,064 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845009882   ⟹   ENSCAFP00845007713
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1050,711,894 - 50,799,655 (-)Ensembl
RefSeq Acc Id: XM_038489233   ⟹   XP_038345161
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11050,419,057 - 50,506,412 (-)NCBI
RefSeq Acc Id: XM_038551237   ⟹   XP_038407165
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01050,893,652 - 50,980,961 (-)NCBI
RefSeq Acc Id: XM_038615133   ⟹   XP_038471061
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01050,705,887 - 50,793,282 (-)NCBI
RefSeq Acc Id: XM_038646912   ⟹   XP_038502840
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1049,693,555 - 49,780,653 (-)NCBI
RefSeq Acc Id: XM_038680516   ⟹   XP_038536444
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01050,711,840 - 50,799,252 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000055077   ⟸   ENSCAFT00000074063
RefSeq Acc Id: ENSCAFP00000003895   ⟸   ENSCAFT00000004211
RefSeq Acc Id: XP_038345161   ⟸   XM_038489233
RefSeq Acc Id: XP_038471061   ⟸   XM_038615133
RefSeq Acc Id: XP_038536444   ⟸   XM_038680516
- UniProtKB: A0A8C0R8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038502840   ⟸   XM_038646912
- UniProtKB: A0A8C0R8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407165   ⟸   XM_038551237
- UniProtKB: A0A8C0R8G1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845007713   ⟸   ENSCAFT00845009882
Protein Domains
F-box   UBR-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002669 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845005550 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004211.5 UniProtKB/TrEMBL
  ENSCAFT00845009882 ENTREZGENE
  ENSCAFT00845009882.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.160.20.10 UniProtKB/TrEMBL
InterPro Beta_helix UniProtKB/TrEMBL
  Carb-bd_sugar_hydrolysis-dom UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_FBXO11 UniProtKB/TrEMBL
  FBXO11_UBR-box UniProtKB/TrEMBL
  NosD_dom UniProtKB/TrEMBL
  Para_beta_helix_rpt-2 UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
  Pectin_lyas_fold UniProtKB/TrEMBL
  Pectin_lyase_fold/virulence UniProtKB/TrEMBL
  Znf_UBR UniProtKB/TrEMBL
NCBI Gene FBXO11 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN UniProtKB/TrEMBL
  PTHR22990:SF20 UniProtKB/TrEMBL
Pfam Beta_helix UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  NosD UniProtKB/TrEMBL
  zf-UBR UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  ZF_UBR UniProtKB/TrEMBL
SMART CASH UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
  ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP SSF51126 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A8C0R8G1 ENTREZGENE
  A0A8I3RSR1_CANLF UniProtKB/TrEMBL
  A0A8P0S8J1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40762 ENTREZGENE