Cxcl8 (C-X-C motif chemokine ligand 8) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cxcl8 (C-X-C motif chemokine ligand 8) Chinchilla lanigera
Analyze
Symbol: Cxcl8
Name: C-X-C motif chemokine ligand 8
RGD ID: 8772136
Description: ENCODES a protein that exhibits chemokine activity (ortholog); interleukin-8 receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cellular response to fibroblast growth factor stimulus (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN chemokine (C-X-C motif) ligand 8 signaling pathway; mTOR signaling pathway; syndecan signaling pathway; ASSOCIATED WITH otitis media; acute asthma (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: chemokine (C-X-C motif) ligand 8; Il8; interleukin 8; interleukin-8
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955474241,501 - 250,643 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955474247,326 - 250,355 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute asthma  (ISO)
Acute Lung Injury  (ISO)
Acute-On-Chronic Liver Failure  (ISO)
adenocarcinoma  (ISO)
alcoholic hepatitis  (ISO)
allergic disease  (ISO)
Bacterial Eye Infections  (ISO)
bacterial gastritis  (ISO)
Bacterial Lung Diseases  (ISO)
Barrett's esophagus  (ISO)
Behcet's disease  (ISO)
biliary atresia  (ISO)
Breast Neoplasms  (ISO)
bullous pemphigoid  (ISO)
Cachexia  (ISO)
Cardiotoxicity  (ISO)
chikungunya  (ISO)
cholestasis  (ISO)
Chronic Hepatitis B  (ISO)
chronic obstructive pulmonary disease  (ISO)
colitis  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
COVID-19  (ISO)
cryptococcosis  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
Down syndrome  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Edema  (ISO)
Endometrial Neoplasms  (ISO)
Experimental Colitis  (ISO)
extrapulmonary tuberculosis  (ISO)
fatty liver disease  (ISO)
Fever  (ISO)
gastroesophageal reflux disease  (ISO)
glioblastoma  (ISO)
glomerulonephritis  (ISO)
Helicobacter Infections  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hyperalgesia  (ISO)
Inflammation  (ISO)
Inflammatory Breast Neoplasms  (ISO)
intermediate coronary syndrome  (ISO)
Intractable Pain  (ISO)
intrahepatic cholestasis  (ISO)
keratitis  (ISO)
Klebsiella pneumonia  (ISO)
lichen disease  (ISO)
liver cirrhosis  (ISO)
Liver Failure  (ISO)
Liver Metastasis  (ISO)
lung non-small cell carcinoma  (ISO)
Lyme Neuroborreliosis  (ISO)
malignant mesothelioma  (ISO)
multiple sclerosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplastic Cell Transformation  (ISO)
Neurosyphilis  (ISO)
oral submucous fibrosis  (ISO)
otitis media  (IEP)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
peptic esophagitis  (ISO)
Pneumococcal Pneumonia  (ISO)
pneumonia  (ISO)
Postherpetic Neuralgia  (ISO)
primary biliary cholangitis  (ISO)
Prostatic Neoplasms  (ISO)
Pseudomonas Infections  (ISO)
psoriatic arthritis  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
Reperfusion Injury  (ISO)
rheumatoid arthritis  (ISO)
Salmonella Infections, Animal  (ISO)
severe acute respiratory syndrome  (ISO)
squamous cell carcinoma  (ISO)
Staphylococcal Infections  (ISO)
stomach carcinoma  (ISO)
Stomach Neoplasms  (ISO)
Thyroid Neoplasms  (ISO)
Tobacco Use Disorder  (ISO)
Toxoplasma Chorioretinitis  (ISO)
Triple Negative Breast Neoplasms  (ISO)
tropical spastic paraparesis  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
viral encephalitis  (ISO)
viral pneumonia  (ISO)
visceral leishmaniasis  (ISO)
Wilson disease  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Cxcl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955474241,501 - 250,643 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955474247,326 - 250,355 (+)NCBIChiLan1.0ChiLan1.0
CXCL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl473,740,541 - 73,743,716 (+)EnsemblGRCh38hg38GRCh38
GRCh38473,740,569 - 73,743,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37474,606,286 - 74,609,433 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,825,139 - 74,828,297 (+)NCBINCBI36hg18NCBI36
Build 34474,971,309 - 74,974,466NCBI
Celera471,966,137 - 71,969,295 (+)NCBI
Cytogenetic Map4q13.3NCBI
HuRef470,417,707 - 70,420,917 (+)NCBIHuRef
CHM1_1474,642,243 - 74,645,454 (+)NCBICHM1_1
Cxcl15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39590,942,393 - 90,950,926 (+)NCBIGRCm39mm39
GRCm39 Ensembl590,942,393 - 90,950,926 (+)Ensembl
GRCm38590,794,534 - 90,803,067 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,794,534 - 90,803,067 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,223,560 - 91,232,093 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,869,771 - 91,877,088 (+)NCBImm8
Celera588,946,158 - 88,954,669 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
CXCL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1456,285,026 - 56,288,308 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,286,708 - 56,288,083 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0450,452,857 - 50,456,015 (-)NCBIMhudiblu_PPA_v0panPan3
CXCL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11362,435,035 - 62,438,354 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1362,434,422 - 62,438,354 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1362,104,414 - 62,107,728 (+)NCBI
ROS_Cfam_1.01363,245,400 - 63,248,688 (+)NCBI
UMICH_Zoey_3.11362,855,624 - 62,858,940 (+)NCBI
UNSW_CanFamBas_1.01362,345,249 - 62,348,566 (+)NCBI
UU_Cfam_GSD_1.01363,485,538 - 63,488,849 (+)NCBI
LOC101964975
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528513,326,322 - 13,329,490 (-)NCBI
SpeTri2.0NW_0049365981,779,471 - 1,781,353 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl869,932,643 - 69,935,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1869,932,646 - 69,935,861 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2874,083,530 - 74,086,749 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXCL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1722,202,497 - 22,205,730 (+)NCBI
ChlSab1.1 Ensembl722,202,527 - 22,204,068 (+)Ensembl
Vero_WHO_p1.0NW_023666084587,605 - 589,481 (-)NCBI
Cxcl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247301,744,097 - 1,747,206 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006629   ⟹   ENSCLAP00000006522
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955474241,501 - 250,643 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000006630   ⟹   ENSCLAP00000006523
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955474243,948 - 250,643 (+)Ensembl
RefSeq Acc Id: XM_013502794   ⟹   XP_013358248
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955474247,326 - 250,355 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358248 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013358248   ⟸   XM_013502794
- Sequence:
RefSeq Acc Id: ENSCLAP00000006523   ⟸   ENSCLAT00000006630
RefSeq Acc Id: ENSCLAP00000006522   ⟸   ENSCLAT00000006629


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004594 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000006522 ENTREZGENE
Ensembl Transcript ENSCLAT00000006629 ENTREZGENE
NCBI Gene Il8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cxcl8  C-X-C motif chemokine ligand 8    chemokine (C-X-C motif) ligand 8  Symbol and/or name change 5135510 APPROVED
2015-08-25 Cxcl8  chemokine (C-X-C motif) ligand 8  Il8  interleukin 8  Symbol and/or name change 5135510 APPROVED