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Gene: IL10RB (interleukin 10 receptor subunit beta) Homo sapiens
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Symbol: IL10RB
Name: interleukin 10 receptor subunit beta
RGD ID: 1345772
Description: Predicted to have interleukin-10 receptor activity. Involved in positive regulation of receptor signaling pathway via JAK-STAT. Predicted to localize to integral component of membrane and plasma membrane. Implicated in hepatitis B and inflammatory bowel disease 25.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDW210B; CRF2-4; CRFB4; cytokine receptor class-II CRF2-4; cytokine receptor class-II member 4; cytokine receptor family 2 member 4; cytokine receptor family II, member 4; D21S58; D21S66; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; interleukin 10 receptor, beta; interleukin-10 receptor subunit 2; interleukin-10 receptor subunit beta
Orthologs:
Mus musculus (house mouse) : Il10rb (interleukin 10 receptor, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il10rb (interleukin 10 receptor subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il10rb (interleukin 10 receptor subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : IL10RB (interleukin 10 receptor subunit beta)
Canis lupus familiaris (dog) : IL10RB (interleukin 10 receptor subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il10rb (interleukin 10 receptor subunit beta)
Sus scrofa (pig) : IL10RB (interleukin 10 receptor subunit beta)
Chlorocebus sabaeus (African green monkey) : IL10RB (interleukin 10 receptor subunit beta)
Heterocephalus glaber (naked mole-rat) : Il10rb (interleukin 10 receptor subunit beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2133,266,367 - 33,310,187 (+)EnsemblGRCh38hg38GRCh38
GRCh382133,266,367 - 33,297,221 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372134,638,665 - 34,669,539 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,560,542 - 33,591,390 (+)NCBINCBI36hg18NCBI36
Build 342133,560,541 - 33,591,390NCBI
Celera2119,824,681 - 19,855,530 (+)NCBI
Cytogenetic Map21q22.11ENTREZGENE
HuRef2120,104,027 - 20,135,023 (+)NCBIHuRef
CHM1_12134,201,309 - 34,232,176 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL10RB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345772
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.