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Gene: IL6 (interleukin 6) Sus scrofa
Symbol: IL6
Name: interleukin 6
Description: ENCODES a protein that exhibits interleukin-6 receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN positive regulation of estradiol secretion; acute inflammatory response (ortholog); aging (ortholog); PARTICIPATES IN interleukin-23 signaling pathway; interleukin-27 signaling pathway; interleukin-6 signaling pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN cytoplasm (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 1,3-thiazolidine-2,4-dione; acrylamide; ambrisentan
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-6; interleukin 6 (interferon, beta 2); interleukin-6; interleukin-6 protein
Homo sapiens (human) : IL6 (interleukin 6)  HGNC  Alliance
Mus musculus (house mouse) : Il6 (interleukin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il6 (interleukin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il6 (interleukin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : IL6 (interleukin 6)
Canis lupus familiaris (dog) : IL6 (interleukin 6)
Chlorocebus sabaeus (African green monkey) : IL6 (interleukin 6)
Heterocephalus glaber (naked mole-rat) : Il6 (interleukin 6)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Note: LOC100628202 and IL6 (GeneID 399500) are annotated as independent loci in Sus scrofa build 10.2. It is unclear at this time if this is from an error in the assembly or if the two are very similar but independent loci in pig. [17 Jun 2014]
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl991,506,340 - 91,511,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1991,506,421 - 91,510,830 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29101,081,042 - 101,085,451 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9q14-q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on IL6
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14098222
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.