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Gene: RT1-Ha (RT1 class II, locus Ha) Rattus norvegicus
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Symbol: RT1-Ha
Name: RT1 class II, locus Ha
Description: Predicted to have peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; cellular response to interferon-gamma; and positive regulation of interferon-gamma production. Predicted to localize to the MHC class II protein complex; cell surface; and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; asthma (multiple); hepatitis B; liver disease (multiple); and onchocerciasis. Orthologous to human HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: major histocompatibility complex class II H-alpha; MGC116352; RT1 class II, locus Ha (mapped); RT1-Ha_mapped; RT1.Ha
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,875,478 - 3,885,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,875,706 - 3,881,461 (+)Ensembl
Rnor_5.0205,955,076 - 5,964,545 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,902,458 - 4,907,767 (-)NCBIRGSC3.4rn4RGSC3.4
Celera206,365,531 - 6,370,840 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on RT1-Ha
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595921
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.