RT1-Ha (RT1 class II, locus Ha) - Rat Genome Database

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Gene: RT1-Ha (RT1 class II, locus Ha) Rattus norvegicus
Analyze
Symbol: RT1-Ha (Ensembl: AABR07044416.1)
Name: RT1 class II, locus Ha
RGD ID: 1595921
Description: Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of type II interferon production. Predicted to be located in cell surface and intracellular membrane-bounded organelle. Predicted to be part of MHC class II protein complex. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; asthma (multiple); hepatitis B; liver disease (multiple); and onchocerciasis. Orthologous to human HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HLA class II histocompatibility antigen, DP alpha 1 chain-like; LOC100911800; major histocompatibility complex class II H-alpha; MGC116352; RLA class II histocompatibility antigen, DP alpha-1 chain-like; RT1 class II, locus Ha (mapped); RT1-Ha_mapped; RT1.Ha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,760,631 - 4,770,662 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,760,118 - 4,770,244 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,516,851 - 5,522,293 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0204,878,601 - 4,884,043 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0205,359,983 - 5,365,396 (-)NCBIRnor_WKY
Rnor_6.0203,875,478 - 3,885,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,875,706 - 3,881,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,955,076 - 5,964,545 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,902,458 - 4,907,767 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,365,531 - 6,370,840 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma. Archer KJ, etal., Mol Genet Genomics. 2010 Apr;283(4):341-9. doi: 10.1007/s00438-010-0522-y. Epub 2010 Feb 18.
2. HLA-DP and susceptibility to insulin-dependent diabetes mellitus in an ethnically mixed population. Associations with other HLA-alleles. Balducci-Silano PL and Layrisse ZE, J Autoimmun. 1995 Jun;8(3):425-37.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. HLA-DR-DQ alleles and HLA-DP alleles are independently associated with susceptibility to different stages of post-schistosomal hepatic fibrosis in the Chinese population. Hirayama K, etal., Tissue Antigens. 1999 Mar;53(3):269-74.
5. Effect of HLA-DPA1 alleles on chronic hepatitis B prognosis and treatment response. Katrinli S, etal., North Clin Istanb. 2017 Jan 25;3(3):168-174. doi: 10.14744/nci.2016.27870. eCollection 2016.
6. Investigation of HLA-DPA1 genotypes as predictors of inflammatory bowel disease in the German, South African, and South Korean populations. Lantermann A, etal., Int J Colorectal Dis. 2002 Jul;17(4):238-44. Epub 2001 Dec 21.
7. Met-11 of HLA class II DP alpha 1 first domain associated with onchocerciasis. Meyer CG, etal., Exp Clin Immunogenet. 1996;13(1):12-9.
8. Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. Noguchi E, etal., PLoS Genet. 2011 Jul;7(7):e1002170. doi: 10.1371/journal.pgen.1002170. Epub 2011 Jul 21.
9. Relationship between HLA-DPA1 mRNA expression and susceptibility to hepatitis B. Ou G, etal., J Viral Hepat. 2019 Jan;26(1):155-161. doi: 10.1111/jvh.13012. Epub 2018 Oct 25.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Distinct Relapse Rates and Risk Predictors After Discontinuing Tenofovir and Entecavir Therapy. Su TH, etal., J Infect Dis. 2018 Mar 28;217(8):1193-1201. doi: 10.1093/infdis/jix690.
15. Allergic and Nonallergic Asthma Have Distinct Phenotypic and Genotypic Features. Takejima P, etal., Int Arch Allergy Immunol. 2017;172(3):150-160. doi: 10.1159/000458151. Epub 2017 Apr 6.
16. Protective effects of HLA-DPA1/DPB1 variants against Hepatitis B virus infection in an Indonesian population. Wasityastuti W, etal., Infect Genet Evol. 2016 Jul;41:177-184. doi: 10.1016/j.meegid.2016.03.034. Epub 2016 Apr 2.
17. Genetic variants in human leukocyte antigen-DP influence both hepatitis C virus persistence and hepatitis C virus F protein generation in the Chinese Han population. Xu X, etal., Int J Mol Sci. 2014 Jun 3;15(6):9826-43. doi: 10.3390/ijms15069826.
Additional References at PubMed
PMID:7721355   PMID:8568247   PMID:11685465   PMID:12477932   PMID:20356827  


Genomics

Comparative Map Data
RT1-Ha
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,760,631 - 4,770,662 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,760,118 - 4,770,244 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,516,851 - 5,522,293 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0204,878,601 - 4,884,043 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0205,359,983 - 5,365,396 (-)NCBIRnor_WKY
Rnor_6.0203,875,478 - 3,885,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,875,706 - 3,881,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,955,076 - 5,964,545 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,902,458 - 4,907,767 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera206,365,531 - 6,370,840 (-)NCBICelera
Cytogenetic Map20p12NCBI
HLA-DPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,064,569 - 33,080,748 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl633,064,569 - 33,080,775 (-)EnsemblGRCh38hg38GRCh38
GRCh37633,032,346 - 33,048,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,140,772 - 33,149,356 (-)NCBINCBI36Build 36hg18NCBI36
Celera634,581,565 - 34,590,149 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,774,786 - 32,790,995 (-)NCBIHuRef
CHM1_1633,034,023 - 33,050,238 (-)NCBICHM1_1
T2T-CHM13v2.0632,885,920 - 32,902,099 (-)NCBIT2T-CHM13v2.0
H2-Pa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,303,587 - 34,304,826 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,303,575 - 34,304,797 (+)EnsemblGRCm39 Ensembl
GRCm381734,084,613 - 34,085,852 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,084,601 - 34,085,823 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,221,558 - 34,222,797 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,695,067 - 33,696,306 (+)NCBIMGSCv36mm8
Celera1736,830,794 - 36,832,033 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
LOC102025724
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,643,238 - 1,651,071 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,644,037 - 1,657,094 (-)NCBIChiLan1.0ChiLan1.0
LOC100995577
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1633,752,638 - 33,768,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,752,638 - 33,761,417 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0632,637,826 - 32,646,501 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC101958908
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,209,458 - 38,216,760 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,743,456 - 25,750,907 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647625,743,512 - 25,750,809 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MHC-DPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,009,361 - 39,017,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,881,227 - 32,886,122 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101698463
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,674,448 - 23,683,662 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,674,935 - 23,683,044 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RT1-Ha
219 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:55
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000036900
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
7175096Tcs1T cell selection QTL 1T cell selectionexpression2047270785024580Rat

Markers in Region
D20Yum78  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,767,852 - 4,768,004 (-)MAPPERmRatBN7.2
mRatBN7.2204,767,852 - 4,768,004 (+)MAPPERmRatBN7.2
Rnor_6.0203,877,946 - 3,878,097NCBIRnor6.0
Rnor_6.0205,285,840 - 5,285,991NCBIRnor6.0
Rnor_5.0207,346,901 - 7,347,052UniSTSRnor5.0
Rnor_5.0205,957,339 - 5,957,490UniSTSRnor5.0
RGSC_v3.4204,905,376 - 4,905,527UniSTSRGSC3.4
Celera206,368,449 - 6,368,600UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 2 8 18 4
Below cutoff 1 3 8 7 7 1 8 10 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000036900   ⟹   ENSRNOP00000033818
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,875,706 - 3,880,876 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086964
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl203,879,582 - 3,881,461 (+)Ensembl
RefSeq Acc Id: NM_001008848   ⟹   NP_001008848
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,764,935 - 4,770,244 (-)NCBI
Rnor_6.0203,875,706 - 3,881,015 (+)NCBI
Rnor_5.0205,955,076 - 5,964,545 (+)NCBI
RGSC_v3.4204,902,458 - 4,907,767 (-)RGD
Celera206,365,531 - 6,370,840 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255916   ⟹   XP_006255978
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2204,760,631 - 4,770,662 (-)NCBI
Rnor_6.0203,875,478 - 3,885,140 (+)NCBI
Rnor_5.0205,955,076 - 5,964,545 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001008848 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255978 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99182 (Get FASTA)   NCBI Sequence Viewer  
  BAA07637 (Get FASTA)   NCBI Sequence Viewer  
  CAE83935 (Get FASTA)   NCBI Sequence Viewer  
  EDL96820 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001008848   ⟸   NM_001008848
- Peptide Label: precursor
- UniProtKB: Q6MGB1 (UniProtKB/TrEMBL),   F7FN89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255978   ⟸   XM_006255916
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000033818   ⟸   ENSRNOT00000036900
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7FN89-F1-model_v2 AlphaFold F7FN89 1-216 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595921 AgrOrtholog
BioCyc Gene G2FUF-4546 BioCyc
Ensembl Genes ENSRNOG00000026669 Ensembl
  ENSRNOG00000045908 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000033818 ENTREZGENE
  ENSRNOP00000033818.5 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036900 ENTREZGENE
  ENSRNOT00000036900.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.10.320.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7383188 IMAGE-MGC_LOAD
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/TrEMBL
  MHC_II_a_N UniProtKB/TrEMBL
KEGG Report rno:24986 UniProtKB/TrEMBL
MGC_CLONE MGC:116352 IMAGE-MGC_LOAD
NCBI Gene 24986 ENTREZGENE
Pfam C1-set UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
PhenoGen RT1-Ha PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt F7FN89 ENTREZGENE
  Q4KLI8_RAT UniProtKB/TrEMBL
  Q6MGB1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7FN89 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 RT1-Ha  RT1 class II, locus Ha  LOC100911800  HLA class II histocompatibility antigen, DP alpha 1 chain-like  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100911800  HLA class II histocompatibility antigen, DP alpha 1 chain-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2007-04-12 RT1-Ha  RT1 class II, locus Ha  RT1-Ha_mapped  RT1 class II, locus Ha (mapped)  Data Merged 737654 APPROVED
2006-11-20 RT1-Ha_mapped  RT1 class II, locus Ha(mapped)  RT1-Ha  RT1 class II, locus Ha  Symbol set to symbol_mapped, name set to name (mapped) 1582166 APPROVED
2006-11-20 RT1-Ha  RT1 class II, locus Ha      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-11 RT1-Ha  RT1 class II, locus Ha      Symbol and Name status set to approved 625702 APPROVED
2002-06-10 RT1-Ha  RT1 class II, locus Ha      Symbol and Name status set to approved 70586 APPROVED