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Gene: LOXL2 (lysyl oxidase like 2) Canis lupus familiaris

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Symbol:

LOXL2

Name:

lysyl oxidase like 2

RGD ID:

12279957

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); copper ion binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of stem cell population maintenance (ortholog); peptidyl-lysine oxidation (ortholog); positive regulation of chondrocyte differentiation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Breast Neoplasms (ortholog); Conotruncal Cardiac Defects (ortholog); FOUND IN basement membrane (inferred); chromatin (inferred); chromosome (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lysyl oxidase homolog 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LOXL2 (lysyl oxidase like 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Loxl2 (lysyl oxidase-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Loxl2 (lysyl oxidase-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	34,095,858 - 34,186,775 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	34,126,335 - 34,185,969 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	34,684,511 - 34,775,173 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	34,303,470 - 34,394,384 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	34,303,481 - 34,394,388 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	34,249,922 - 34,341,273 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	34,104,318 - 34,195,732 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	34,259,681 - 34,351,266 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

Breast Neoplasms (ISO)

Conotruncal Cardiac Defects (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Liver Cirrhosis (ISO)

hepatitis B (ISO)

hepatitis C (ISO)

Neoplasm Invasiveness (ISO)

Neoplastic Cell Transformation (ISO)

primary biliary cholangitis (ISO)

Wilson disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

collagen fibril organization (IEA)

endothelial cell migration (IEA)

endothelial cell proliferation (IEA)

epithelial to mesenchymal transition (IEA)

heterochromatin organization (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of stem cell population maintenance (ISO)

negative regulation of transcription by RNA polymerase II (IEA)

peptidyl-lysine oxidation (ISO)

positive regulation of chondrocyte differentiation (ISO)

positive regulation of epithelial to mesenchymal transition (IEA)

protein modification process (IEA)

response to copper ion (IEA)

response to hypoxia (ISO)

sprouting angiogenesis (IEA)

Cellular Component

basement membrane (IEA)

chromatin (IEA)

chromosome (IEA)

endoplasmic reticulum (IEA)

extracellular region (IEA)

extracellular space (IEA)

membrane (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

calcium ion binding (IEA)

copper ion binding (IEA)

metal ion binding (IEA)

oligosaccharide binding (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (IEA)

protein binding (ISO)

protein-lysine 6-oxidase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOXL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	34,095,858 - 34,186,775 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	34,126,335 - 34,185,969 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	34,684,511 - 34,775,173 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	34,303,470 - 34,394,384 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	34,303,481 - 34,394,388 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	34,249,922 - 34,341,273 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	34,104,318 - 34,195,732 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	34,259,681 - 34,351,266 (+)	NCBI		UU_Cfam_GSD_1.0

LOXL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	23,296,897 - 23,404,120 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	23,296,897 - 23,425,328 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	23,154,410 - 23,261,633 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	23,210,355 - 23,317,667 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	23,210,640 - 23,317,575	NCBI
Celera	8	22,116,981 - 22,224,289 (-)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	21,700,441 - 21,807,111 (-)	NCBI		HuRef
CHM1_1	8	23,356,541 - 23,463,832 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	23,571,770 - 23,679,001 (-)	NCBI		T2T-CHM13v2.0

Loxl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	69,846,085 - 69,933,283 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	69,846,517 - 69,933,283 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	69,608,692 - 69,695,834 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	69,609,068 - 69,695,834 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,009,283 - 70,095,641 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	68,344,556 - 68,428,775 (+)	NCBI		MGSCv36	mm8
Celera	14	67,164,771 - 67,231,456 (+)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.06	NCBI

Loxl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,091,547 - 51,182,843 (+)	NCBI		GRCr8
mRatBN7.2	15	44,683,449 - 44,773,067 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	44,683,880 - 44,773,067 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	48,801,847 - 48,888,730 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	49,913,342 - 50,000,223 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	46,772,671 - 46,859,556 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	51,276,022 - 51,365,238 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	51,303,909 - 51,365,234 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,005,461 - 55,092,980 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	49,982,103 - 50,068,902 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,024,097 - 50,084,571 (+)	NCBI
Celera	15	44,366,507 - 44,453,187 (+)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

Loxl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	46,504,440 - 46,584,016 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	46,503,226 - 46,583,807 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOXL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	41,802,508 - 41,909,114 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	17,529,707 - 17,636,058 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	22,547,303 - 22,653,676 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	19,483,331 - 19,589,522 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	19,483,335 - 19,589,522 (-)	Ensembl	panpan1.1		panPan2

Loxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	11,704,822 - 11,789,837 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	6,781,321 - 6,865,768 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	6,781,563 - 6,865,662 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOXL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	7,435,867 - 7,540,704 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	7,435,861 - 7,540,699 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOXL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	21,416,821 - 21,516,923 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	21,416,787 - 21,516,854 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	20,707,763 - 20,805,731 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Loxl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	18,568,607 - 18,621,785 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	18,567,367 - 18,644,528 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LOXL2
1615 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038435408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038435409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038458319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038510347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038510348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038573799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038573800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038638114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038638115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_543244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000014616 ⟹ ENSCAFP00000013518

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	25	34,126,335 - 34,185,969 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845030167 ⟹ ENSCAFP00845023665

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	25	34,303,481 - 34,394,388 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845030336 ⟹ ENSCAFP00845023789

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	25	34,303,481 - 34,394,378 (+)	Ensembl

RefSeq Acc Id:

XM_038435408 ⟹ XP_038291336

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	25	34,303,470 - 34,394,384 (+)	NCBI

RefSeq Acc Id:

XM_038435409 ⟹ XP_038291337

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	25	34,303,470 - 34,394,384 (+)	NCBI

RefSeq Acc Id:

XM_038458319 ⟹ XP_038314247

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	25	34,684,511 - 34,775,173 (+)	NCBI

RefSeq Acc Id:

XM_038510347 ⟹ XP_038366275

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	25	34,249,922 - 34,341,273 (+)	NCBI

RefSeq Acc Id:

XM_038510348 ⟹ XP_038366276

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	25	34,249,922 - 34,341,273 (+)	NCBI

RefSeq Acc Id:

XM_038573799 ⟹ XP_038429727

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	25	34,259,681 - 34,351,266 (+)	NCBI

RefSeq Acc Id:

XM_038573800 ⟹ XP_038429728

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	25	34,259,681 - 34,351,266 (+)	NCBI

RefSeq Acc Id:

XM_038638114 ⟹ XP_038494042

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	25	34,104,318 - 34,195,732 (+)	NCBI

RefSeq Acc Id:

XM_038638115 ⟹ XP_038494043

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	25	34,104,318 - 34,195,732 (+)	NCBI

RefSeq Acc Id:

XM_543244 ⟹ XP_543244

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	25	34,095,858 - 34,186,775 (+)	NCBI
Dog10K_Boxer_Tasha	25	34,684,511 - 34,775,173 (+)	NCBI

Sequence:

show sequence

AAGCGTAAAGCGTCCACTCCAGCCGGTGGCGTCCTGGACTCGGAGCCTCCTTTCTCCAGCGGCC
TGAGACGGCGGCTCGGGCAAGGGGCTCAGCGGCGACGGGCGCGCAGAGAGGCCACCGTGGAGAG
CTGGCCCCAGCCTGGCCGCTGCGGGCCCCTGCTGCCAAGACGGTCCGGCCTGTCGCTGGATCAG
GCCCTCCGGCCCGAGGGTGAGGACGAAGACCGGGATGGCGAGGCGTGGAGGCCCGCGCCTGGGC
GGCTGCCTGGCCTTGCTCTCGCTGCTCCCATCCCTGAGCCTGGCGCAGTACGAGGCCTGGCCCT
ACTACCCTGAATACTTCCAGCAGCCGGCCCCCGAGTACCACCGGCCTCAGGTGCCCTCGGATGT
CGCCAAGATCCAGCTGCGCCTGGCGGGCCAGAAGAGGAAGCACAGCGAGGGGCGGGTGGAGGTG
TACTACGACGGCCAGTGGGGCACCGTGTGCGACGATGACTTCTCCATCCACGCGGCCCACGTCG
TCTGCCGGGAGCTGGGATACGTGGAGGCCAAGGCCTGGACCGCCAGCTCCTCCTACGGCAAAGG
GGAAGGACCCATCTGGTTGGACAATATCTACTGCACAGGCAGAGAGGCCACCCTCGCTGCCTGC
TCCTCCAATGGCTGGGGTGTCACCGACTGCAAGCACACAGAAGACGTGGGCGTGGTGTGCAGTG
ACAAAAGGATTCCTGGTTTCAAATTTGACAACTCATTGGTCAACCATATAGAGAACTTGAACAT
CCAGGTGGAGGACATCCGGATCCGAGCCATCCTATCCGCCTACCGCAAGCGCACTCCCGTGACA
GAGGGCTATGTAGAGGTGAAGGATGGCAAGACCTGGAAGCAGATCTGTGACAAGCATTGGACAG
CCAAGAATTCCCGCGTGGTCTGCGGCATGTTTGGCTTCCCCGGGGAGAAGACGTACAACGCCAA
AGTGTACAAGATGTTCGCCGCCCGGAAGAAACAGCGCTACTGGCCCTACTCCATGGACTGCACA
GGCACGGAGGCTCATATCTCCAGCTGCAAGCTTGGCACTCAGGTGTCGCTGGACCCCGTGAAGA
ATGTCACCTGTGAGAATGGGCTGCCGGCTGTGGTGAGTTGTGTGCCTGGCCAGGTCTTCAGCCC
CGACGGGCCCTCAAGATTCCGGAAAGCCTACAAGCCAGAGCAACCCCTGGTGCGGTTGAGAGGC
GGTGCCAACATCGGGGAGGGCCGAGTGGAGGTGCTCAAGAATGGAGAATGGGGGACCATCTGTG
ACGACAAGTGGGACCTGGTGTCTGCCAGTGTGGTCTGCAGAGAGCTGGGCTTTGGGAGTGCCAA
AGAGGCCATCACTGGCTCCCAGCTGGGGCAAGGGATAGGACCCATCCACCTCAATGAAATCGAG
TGCACTGGGAATGAGAAGTCCATTATAGACTGTAAATTCAATGCTGAGTCCCAGGGCTGCAACC
ACGAGGAAGATGCTGGTGTGAGATGTAACATCCCCGCCATGGGCTTCCAGAAGAAGCTGCGCCT
GAACGGGGGCCGGAACCCCTACGAGGGCCGGGTGGAGGTGCTGGTGGAGAGGAACGGGTCCCTC
GTATGGGGGACGGTGTGTGGCGAGAACTGGGGCATTGTGGAGGCCATGGTGGTCTGCCGGCAGC
TGGGCCTGGGGTTTGCCAGCAACGCCTTCCAGGAGACCTGGTACTGGCACGGAAATATGTACGC
CAACAAAGTGGTCATGAGTGGAGTGAAGTGCTCGGGAACGGAGCTGTCCCTGGCGCACTGCCGC
CACGACGGGGAGGATGTGGCCTGCCCCCAGGGCGCGGTGCAGTATGGGGCTGGAGTGGCCTGCT
CAGAAACGGCCCCTGACCTGGTCCTCAATGCGGAGATTGTCCAGCAGAGCACCTACCTGGAGGA
CCGTCCCATGTTCATGCTCCAGTGCGCCATGGAGGAGAACTGCCTCTCGGCCTCGGCTGCCCAG
ACCAACCCCACCACTGGCTACCGACGGCTCCTGCGCTTCTCCTCCCAGATCCACAACAATGGAC
AGTCTGACTTCCGACCCAAGAATGGCCGCCACGCGTGGATCTGGCATGATTGCCACAGGCACTA
CCACAGCATGGAAGTGTTCACCCACTATGACCTCTTGAACCTCAATGGTACCAAGGTGGCAGAG
GGCCACAAAGCCAGCTTCTGCTTGGAGGACACAGAATGTGAAGGAGACATCCAGAAGAGTTACG
AATGTGCCAACTTCGGTGAGCAGGGCATCACCATGGGCTGCTGGGACATGTATCGCCATGACAT
CGACTGCCAGTGGGTCGACATCACTGACGTACCCCCTGGAGACTACCTGTTCCAGGTCGTCATT
AACCCCAACTACGAGGTAGCAGAGTCGGACTACACCAACAACATCATGAAGTGCAGGACCCGCT
ACGACGGCCACCGCATCTGGATGTACAACTGCCACATAGGCGGTTCCTTCAGTGAAGAGACGGA
AAAAAAGTTTGAACACTTCAGTGGACTCATAAATAACCAGCTCTCTGCACGGTAAAGCACCAGG
TCACCACCGCCCGTCTCGGGGCCCCGGCGCACCTTCCCCAACAGCTGCAGTCCGAGGGCCACAA
TCTCTCCTCGTCCAGCCCTGTGCCTGCCGTCTCAACCCCCTGCAGCCTCGTCCGAGGCTCAGGA
GGAAGGCGTGTGCCTGTCACTTGCTGGGGGCTGCCGCCTGACCTCGGGAGCCTGGGACGACTAC
CAGGGTTGTGGCCACCAAGAGCCATCCAGCCTGGGACCCCAGGAGCACGGGTTAGCAGCGGCCG
GTCCCACCTACCCCGCAGTCTGCCCCTTGTAGGACACCCCCCCACCCAGCTCACGCCAGGTAAC
ACGGGGCCCCATCGGTGTTGTGAGCTGTCCACCCAAGGGGTTTGGGCTGAATTCCATCTTCCTC
CTCTTCAGTCATTTCCAGCCAACCTGAATATCTAGACCCTTCTTCCAATTAAAGACTGCCTCTC
CTCTGTTATATTCACATATACAAATAATGCTGCCACATGTTTTCTAATTAGGTGAGCGAGCTCA
GAGTTGGTGCTTCTTCCCCCACCCCCCACTCCGAAATTCTCTTACAAGATACCATTATTATATT
TTCACAGACTTTGAAACACAAAGTAACTTAGTGGCATTTAATATTGGGCATCTGGGCCTTTGAA
AGTATAGCTCAGAAGAAAAACCAACCCACCTGTGTAAGTGACTCATCTTTCTGTTGTTCCAATT
CTGTGGGTAACTGATGTAACGGTGCTATAAACCTGGGTCCTGGGTGATGAGGACACCCACTGAG
CGCCATGTGTCATCACAGACACTTACACATACTTGAAACTTTAAATAAAAGGTTTATGA

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Protein Sequences


Protein RefSeqs	XP_038291336	(Get FASTA)	NCBI Sequence Viewer
	XP_038291337	(Get FASTA)	NCBI Sequence Viewer
	XP_038314247	(Get FASTA)	NCBI Sequence Viewer
	XP_038366275	(Get FASTA)	NCBI Sequence Viewer
	XP_038366276	(Get FASTA)	NCBI Sequence Viewer
	XP_038429727	(Get FASTA)	NCBI Sequence Viewer
	XP_038429728	(Get FASTA)	NCBI Sequence Viewer
	XP_038494042	(Get FASTA)	NCBI Sequence Viewer
	XP_038494043	(Get FASTA)	NCBI Sequence Viewer
	XP_543244	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000013518.5
	ENSCAFP00000070159.1
	ENSCAFP00030033351.1
	ENSCAFP00845023665.1
	ENSCAFP00845023789
	ENSCAFP00845023789.1

RefSeq Acc Id:	XP_543244 ⟸ XM_543244
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0KFN8 (UniProtKB/TrEMBL), A0A8C0RPV7 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL), A0A8I3P9Y5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARRGGPRLGGCLALLSLLPSLSLAQYEAWPYYPEYFQQPAPEYHRPQVPSDVAKIQLRLAGQK RKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKAWTASSSYGKGEGPIWLDNIYC TGREATLAACSSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLVNHIENLNIQVEDIRIRAIL SAYRKRTPVTEGYVEVKDGKTWKQICDKHWTAKNSRVVCGMFGFPGEKTYNAKVYKMFAARKKQ RYWPYSMDCTGTEAHISSCKLGTQVSLDPVKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYK PEQPLVRLRGGANIGEGRVEVLKNGEWGTICDDKWDLVSASVVCRELGFGSAKEAITGSQLGQG IGPIHLNEIECTGNEKSIIDCKFNAESQGCNHEEDAGVRCNIPAMGFQKKLRLNGGRNPYEGRV EVLVERNGSLVWGTVCGENWGIVEAMVVCRQLGLGFASNAFQETWYWHGNMYANKVVMSGVKCS GTELSLAHCRHDGEDVACPQGAVQYGAGVACSETAPDLVLNAEIVQQSTYLEDRPMFMLQCAME ENCLSASAAQTNPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDL LNLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWVDITDVP PGDYLFQVVINPNYEVAESDYTNNIMKCRTRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLIN NQLSAR hide sequence

Ensembl Acc Id:

ENSCAFP00000013518 ⟸ ENSCAFT00000014616

RefSeq Acc Id:	XP_038366275 ⟸ XM_038510347
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038366276 ⟸ XM_038510348
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038494042 ⟸ XM_038638114
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038494043 ⟸ XM_038638115
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038291336 ⟸ XM_038435408
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3P9Y5 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038291337 ⟸ XM_038435409
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0KFN8 (UniProtKB/TrEMBL), A0A8C0RPV7 (UniProtKB/TrEMBL), A0A8I3P9Y5 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038314247 ⟸ XM_038458319
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3P9Y5 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038429727 ⟸ XM_038573799
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3P9Y5 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038429728 ⟸ XM_038573800
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0KFN8 (UniProtKB/TrEMBL), A0A8C0RPV7 (UniProtKB/TrEMBL), A0A8I3P9Y5 (UniProtKB/TrEMBL), A0A8P0NBJ1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845023665 ⟸ ENSCAFT00845030167

Ensembl Acc Id:

ENSCAFP00845023789 ⟸ ENSCAFT00845030336

Protein Domains

SRCR

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009187	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030020717	UniProtKB/TrEMBL
	ENSCAFG00845017019	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000014616.5	UniProtKB/TrEMBL
	ENSCAFT00000100169.1	UniProtKB/TrEMBL
	ENSCAFT00030038236.1	UniProtKB/TrEMBL
	ENSCAFT00845030167.1	UniProtKB/TrEMBL
	ENSCAFT00845030336	ENTREZGENE
	ENSCAFT00845030336.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.250.10	UniProtKB/TrEMBL
InterPro	LOX-like_protein	UniProtKB/TrEMBL
	Lysyl_oxidase	UniProtKB/TrEMBL
	Lysyl_oxidase_CS	UniProtKB/TrEMBL
	SRCR	UniProtKB/TrEMBL
	SRCR-like_dom	UniProtKB/TrEMBL
	SRCR-like_dom_sf	UniProtKB/TrEMBL
NCBI Gene	LOXL2	ENTREZGENE
PANTHER	LYSYL OXIDASE HOMOLOG 2	UniProtKB/TrEMBL
	LYSYL OXIDASE-LIKE-RELATED	UniProtKB/TrEMBL
Pfam	Lysyl_oxidase	UniProtKB/TrEMBL
	SRCR	UniProtKB/TrEMBL
PRINTS	LYSYLOXIDASE	UniProtKB/TrEMBL
	SPERACTRCPTR	UniProtKB/TrEMBL
PROSITE	LYSYL_OXIDASE	UniProtKB/TrEMBL
	SRCR_1	UniProtKB/TrEMBL
	SRCR_2	UniProtKB/TrEMBL
SMART	SM00202	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56487	UniProtKB/TrEMBL
UniProt	A0A8C0KFN8	ENTREZGENE
	A0A8C0RPV7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NSB7_CANLF	UniProtKB/TrEMBL
	A0A8I3P9Y5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NBJ1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0PJZ2_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:42739	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD