LOXL2 (lysyl oxidase like 2) - Rat Genome Database

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Gene: LOXL2 (lysyl oxidase like 2) Sus scrofa
Analyze
Symbol: LOXL2
Name: lysyl oxidase like 2
RGD ID: 13930235
Description: ENCODES a protein that exhibits calcium ion binding (inferred); copper ion binding (inferred); metal ion binding (inferred); INVOLVED IN peptidyl-lysine oxidation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Breast Neoplasms (ortholog); Conotruncal Cardiac Defects (ortholog); FOUND IN basement membrane (inferred); chromatin (inferred); chromosome (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lysyl oxidase homolog 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl147,435,867 - 7,540,704 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1147,435,861 - 7,540,699 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOXL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl147,435,867 - 7,540,704 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1147,435,861 - 7,540,699 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOXL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38823,296,897 - 23,404,120 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl823,296,897 - 23,425,328 (-)EnsemblGRCh38hg38GRCh38
GRCh37823,154,410 - 23,261,633 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36823,210,355 - 23,317,667 (-)NCBINCBI36Build 36hg18NCBI36
Build 34823,210,640 - 23,317,575NCBI
Celera822,116,981 - 22,224,289 (-)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef821,700,441 - 21,807,111 (-)NCBIHuRef
CHM1_1823,356,541 - 23,463,832 (-)NCBICHM1_1
T2T-CHM13v2.0823,571,770 - 23,679,001 (-)NCBIT2T-CHM13v2.0
Loxl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391469,846,085 - 69,933,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1469,846,517 - 69,933,283 (+)EnsemblGRCm39 Ensembl
GRCm381469,608,692 - 69,695,834 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1469,609,068 - 69,695,834 (+)EnsemblGRCm38mm10GRCm38
MGSCv371470,009,283 - 70,095,641 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361468,344,556 - 68,428,775 (+)NCBIMGSCv36mm8
Celera1467,164,771 - 67,231,456 (+)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.06NCBI
Loxl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,091,547 - 51,182,843 (+)NCBIGRCr8
mRatBN7.21544,683,449 - 44,773,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1544,683,880 - 44,773,067 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1548,801,847 - 48,888,730 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01549,913,342 - 50,000,223 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01546,772,671 - 46,859,556 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01551,276,022 - 51,365,238 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,303,909 - 51,365,234 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,005,461 - 55,092,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41549,982,103 - 50,068,902 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,024,097 - 50,084,571 (+)NCBI
Celera1544,366,507 - 44,453,187 (+)NCBICelera
Cytogenetic Map15p11NCBI
Loxl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540346,504,440 - 46,584,016 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540346,503,226 - 46,583,807 (-)NCBIChiLan1.0ChiLan1.0
LOXL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2741,802,508 - 41,909,114 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1817,529,707 - 17,636,058 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0822,547,303 - 22,653,676 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1819,483,331 - 19,589,522 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl819,483,335 - 19,589,522 (-)Ensemblpanpan1.1panPan2
LOXL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12534,095,858 - 34,186,775 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2534,126,335 - 34,185,969 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2534,684,511 - 34,775,173 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02534,303,470 - 34,394,384 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2534,303,481 - 34,394,388 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12534,249,922 - 34,341,273 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02534,104,318 - 34,195,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02534,259,681 - 34,351,266 (+)NCBIUU_Cfam_GSD_1.0
Loxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494311,704,822 - 11,789,837 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365556,781,321 - 6,865,768 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365556,781,563 - 6,865,662 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOXL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1821,416,821 - 21,516,923 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl821,416,787 - 21,516,854 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605220,707,763 - 20,805,731 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Loxl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475818,568,607 - 18,621,785 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475818,567,367 - 18,644,528 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOXL2
3381 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 10 3 5 14 12 10 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000046243   ⟹   ENSSSCP00000045152
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl147,435,867 - 7,540,704 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000079299   ⟹   ENSSSCP00000065367
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl147,440,991 - 7,540,702 (-)Ensembl
RefSeq Acc Id: XM_021074114   ⟹   XP_020929773
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1147,435,861 - 7,540,699 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021074115   ⟹   XP_020929774
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1147,435,861 - 7,540,575 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020929773 (Get FASTA)   NCBI Sequence Viewer  
  XP_020929774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000045152
  ENSSSCP00000045152.2
  ENSSSCP00000065367.1
  ENSSSCP00015037696.1
  ENSSSCP00070039952.1
  ENSSSCP00070039960.1
RefSeq Acc Id: XP_020929773   ⟸   XM_021074114
- UniProtKB: A0A8D0UAH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020929774   ⟸   XM_021074115
- UniProtKB: A0A8D0UAH5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000065367   ⟸   ENSSSCT00000079299
Ensembl Acc Id: ENSSSCP00000045152   ⟸   ENSSSCT00000046243
Protein Domains
SRCR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033608 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015068784 UniProtKB/TrEMBL
  ENSSSCG00070023729 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000046243 ENTREZGENE
  ENSSSCT00000046243.3 UniProtKB/TrEMBL
  ENSSSCT00000079299.1 UniProtKB/TrEMBL
  ENSSSCT00015092182.1 UniProtKB/TrEMBL
  ENSSSCT00070047352.1 UniProtKB/TrEMBL
  ENSSSCT00070047360.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.250.10 UniProtKB/TrEMBL
InterPro LOX-like_protein UniProtKB/TrEMBL
  Lysyl_oxidase UniProtKB/TrEMBL
  Lysyl_oxidase_CS UniProtKB/TrEMBL
  SRCR UniProtKB/TrEMBL
  SRCR-like_dom UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/TrEMBL
NCBI Gene LOXL2 ENTREZGENE
PANTHER LYSYL OXIDASE HOMOLOG 2 UniProtKB/TrEMBL
  LYSYL OXIDASE-LIKE-RELATED UniProtKB/TrEMBL
Pfam Lysyl_oxidase UniProtKB/TrEMBL
  SRCR UniProtKB/TrEMBL
PRINTS LYSYLOXIDASE UniProtKB/TrEMBL
  SPERACTRCPTR UniProtKB/TrEMBL
PROSITE LYSYL_OXIDASE UniProtKB/TrEMBL
  SRCR_1 UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
SMART SM00202 UniProtKB/TrEMBL
Superfamily-SCOP SSF56487 UniProtKB/TrEMBL
UniProt A0A287AM88_PIG UniProtKB/TrEMBL
  A0A4X1VAA3_PIG UniProtKB/TrEMBL
  A0A5G2R482_PIG UniProtKB/TrEMBL
  A0A8D0UAH5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89781 ENTREZGENE