IL12A Human (S)-nicotine multiple interactions ISO Il12a (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] more ... CTD PMID:21237301 IL12A Human 1,2-dichloroethane decreases expression ISO Il12a (Mus musculus) 6480464 ethylene dichloride results in decreased expression of IL12A mRNA CTD PMID:28960355 IL12A Human 1-chloro-2,4-dinitrobenzene increases expression ISO Il12a (Rattus norvegicus) 6480464 Dinitrochlorobenzene results in increased expression of IL12A mRNA CTD PMID:25449201 IL12A Human 1-chloro-2,4-dinitrobenzene decreases expression ISO Il12a (Mus musculus) 6480464 Dinitrochlorobenzene results in decreased expression of IL12A mRNA CTD PMID:28219650 IL12A Human 17beta-estradiol multiple interactions ISO Il12a (Mus musculus) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of IL12A mRNA CTD PMID:19693291 IL12A Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IL12A mRNA CTD PMID:36828454 IL12A Human 17beta-estradiol multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines more ... CTD PMID:20130130 IL12A Human 17beta-estradiol decreases expression ISO Il12a (Mus musculus) 6480464 Estradiol results in decreased expression of IL12A mRNA CTD PMID:19693291 IL12A Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO Il12a (Rattus norvegicus) 6480464 2 more ... CTD PMID:27291303 IL12A Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO Il12a (Mus musculus) 6480464 2 more ... CTD PMID:33078840 IL12A Human 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:21703328 IL12A Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Il12a (Mus musculus) 6480464 Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:21097750 IL12A Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA]] more ... CTD PMID:27783115 IL12A Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Il12a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of IL12A mRNA CTD PMID:12167310 IL12A Human 2,3-bis(4-hydroxyphenyl)propionitrile multiple interactions ISO Il12a (Mus musculus) 6480464 2 and 3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A protein] CTD PMID:30017638 IL12A Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Il12a (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA CTD PMID:15973123 IL12A Human 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide more ... CTD PMID:25680285 IL12A Human 3',5'-cyclic AMP multiple interactions EXP 6480464 Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein] CTD PMID:15843518 IL12A Human 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Il12a (Mus musculus) 6480464 3 more ... CTD PMID:29216392 IL12A Human 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Il12a (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of IL12A mRNA CTD PMID:33078840 IL12A Human 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO Il12a (Mus musculus) 6480464 [NFE2L2 gene mutant form results in increased susceptibility to 3 more ... CTD PMID:30825315 IL12A Human 3-iodobenzyl-5'-N-methylcarboxamidoadenosine multiple interactions EXP 6480464 N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16116186 IL12A Human 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of IL12A mRNA CTD PMID:14993811 IL12A Human 3-phenylprop-2-enal affects expression ISO Il12a (Mus musculus) 6480464 cinnamaldehyde affects the expression of IL12A mRNA CTD PMID:28219650 IL12A Human 3-phenylprop-2-enal multiple interactions ISO Il12a (Mus musculus) 6480464 NFE2L2 protein inhibits the reaction [cinnamaldehyde results in increased expression of IL12A mRNA] CTD PMID:28219650 IL12A Human 4,4'-sulfonyldiphenol decreases expression ISO Il12a (Mus musculus) 6480464 bisphenol S results in decreased expression of IL12A mRNA CTD PMID:33078840 IL12A Human 4-methylhistamine multiple interactions EXP 6480464 4-methylhistamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:11752121 and PMID:12364868 IL12A Human 4-nitroquinoline N-oxide increases expression ISO Il12a (Mus musculus) 6480464 4-Nitroquinoline-1-oxide results in increased expression of IL12A mRNA CTD PMID:22561872 IL12A Human 7,12-dimethyltetraphene multiple interactions ISO Il12a (Mus musculus) 6480464 IL12A results in decreased susceptibility to [9 more ... CTD PMID:22359662 IL12A Human 9-cis-retinoic acid multiple interactions EXP 6480464 Alitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] and Alitretinoin results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:17118196 and PMID:17475839 IL12A Human acetylsalicylic acid multiple interactions EXP 6480464 Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:15379866 IL12A Human actinomycin D multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of IL12A mRNA CTD PMID:38460933 IL12A Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of IL12A protein CTD PMID:20106945 IL12A Human aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of IL12A mRNA CTD PMID:22100608 IL12A Human all-trans-retinoic acid multiple interactions EXP 6480464 RARA protein affects the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:16872382 and PMID:17118196 IL12A Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of IL12A mRNA CTD PMID:15189689 and PMID:16872382 IL12A Human ammonium chloride affects expression ISO Il12a (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of IL12A mRNA CTD PMID:16483693 IL12A Human anthranilic acid multiple interactions EXP 6480464 anthranilic acid analog inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 IL12A Human antimony(0) affects response to substance ISO Il12a (Mus musculus) 6480464 IL12A protein affects the susceptibility to Antimony CTD PMID:11023473 IL12A Human apilimod multiple interactions EXP 6480464 apilimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:17053051 IL12A Human aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of IL12A mRNA CTD PMID:33212167 IL12A Human arsane decreases expression EXP 6480464 Arsenic results in decreased expression of IL12A mRNA CTD PMID:27838757 IL12A Human arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of IL12A mRNA CTD PMID:27838757 IL12A Human arsenite(3-) multiple interactions ISO Il12a (Mus musculus) 6480464 arsenite inhibits the reaction [lipopolysaccharide more ... CTD PMID:25680285 IL12A Human arsenite(3-) multiple interactions EXP 6480464 arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide more ... CTD PMID:25680285 IL12A Human atorvastatin calcium decreases expression EXP 6480464 Atorvastatin results in decreased expression of IL12A mRNA CTD PMID:12492458 IL12A Human azathioprine multiple interactions EXP 6480464 Azathioprine results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:19584951 IL12A Human benzene affects response to substance EXP 6480464 IL12A gene SNP affects the susceptibility to Benzene CTD PMID:16230423 IL12A Human benzo[a]pyrene multiple interactions ISO Il12a (Mus musculus) 6480464 Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of IL12A mRNA] CTD PMID:30165701 IL12A Human benzo[a]pyrene decreases expression ISO Il12a (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of IL12A mRNA CTD PMID:34437932 IL12A Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of IL12A mRNA CTD PMID:32234424 IL12A Human benzo[a]pyrene increases expression ISO Il12a (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of IL12A mRNA CTD PMID:30165701 and PMID:33245929 IL12A Human benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7 more ... CTD PMID:20382639 IL12A Human Benzo[ghi]perylene increases expression EXP 6480464 1 and 12-benzoperylene results in increased expression of IL12A mRNA CTD PMID:35182551 IL12A Human Benzo[ghi]perylene multiple interactions EXP 6480464 [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide co-treated with 1 and 12-benzoperylene] results in increased expression of IL12A mRNA CTD PMID:35182551 IL12A Human beta-D-glucan multiple interactions EXP 6480464 [beta-Glucans co-treated with resiquimod co-treated with IFNG protein] results in increased expression of IL12A mRNA more ... CTD PMID:18490488 IL12A Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of IL12A mRNA CTD PMID:38218311 IL12A Human beta-naphthoflavone multiple interactions ISO Il12a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL12A mRNA CTD PMID:18164116 IL12A Human betulin increases expression ISO Il12a (Mus musculus) 6480464 betulin results in increased expression of IL12A mRNA CTD PMID:25756279 IL12A Human betulin multiple interactions ISO Il12a (Mus musculus) 6480464 betulin results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:25756279 IL12A Human bisphenol A multiple interactions ISO Il12a (Rattus norvegicus) 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of IL12A mRNA CTD PMID:26496021 IL12A Human bisphenol A increases expression ISO Il12a (Mus musculus) 6480464 bisphenol A results in increased expression of IL12A mRNA CTD PMID:33706241 IL12A Human bisphenol A multiple interactions ISO Il12a (Mus musculus) 6480464 [bisphenol A affects the susceptibility to Ovalbumin] results in decreased expression of and results in decreased secretion of [IL12A protein binds to IL12B protein] more ... CTD PMID:29737898 more ... IL12A Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of IL12A mRNA and bisphenol A affects the expression of IL12A protein CTD PMID:31715268 IL12A Human bisphenol F multiple interactions ISO Il12a (Mus musculus) 6480464 bisphenol F results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:35278557 IL12A Human Butylbenzyl phthalate increases expression ISO Il12a (Mus musculus) 6480464 butylbenzyl phthalate results in increased expression of IL12A mRNA CTD PMID:36746855 IL12A Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL12A mRNA CTD PMID:35301059 IL12A Human cadmium dichloride decreases expression ISO Il12a (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of IL12A mRNA alternative form CTD PMID:24583143 IL12A Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL12A mRNA CTD PMID:35301059 IL12A Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of IL12A mRNA CTD PMID:38382870 IL12A Human caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of IL12A mRNA CTD PMID:28089782 IL12A Human cannabidiol multiple interactions ISO Il12a (Mus musculus) 6480464 Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA] CTD PMID:27256343 IL12A Human carbamate ester increases expression EXP 6480464 Carbamates analog results in increased expression of IL12A protein CTD PMID:19111005 and PMID:19376255 IL12A Human carbamazepine decreases expression ISO Il12a (Mus musculus) 6480464 Carbamazepine results in decreased expression of IL12A mRNA CTD PMID:22790970 IL12A Human carvedilol multiple interactions EXP 6480464 carvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]] and carvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15229385 IL12A Human casticin decreases expression EXP 6480464 casticin results in decreased expression of IL12A mRNA CTD PMID:27862857 IL12A Human CGS-21680 multiple interactions EXP 6480464 [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in decreased expression of IL12A mRNA CTD PMID:22923002 IL12A Human chlorophyllin multiple interactions ISO Il12a (Mus musculus) 6480464 chlorophyllin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:16275627 IL12A Human chloroprene decreases expression ISO Il12a (Mus musculus) 6480464 Chloroprene results in decreased expression of IL12A mRNA CTD PMID:23125180 IL12A Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IL12A mRNA CTD PMID:19561079 and PMID:27392435 IL12A Human clofibrate increases expression ISO Il12a (Mus musculus) 6480464 Clofibrate results in increased expression of IL12A mRNA CTD PMID:17585979 IL12A Human colforsin daropate hydrochloride decreases expression ISO Il12a (Mus musculus) 6480464 Colforsin results in decreased expression of IL12A protein CTD PMID:10996031 IL12A Human copper atom increases expression ISO Il12a (Rattus norvegicus) 6480464 Copper results in increased expression of IL12A mRNA CTD PMID:30556269 IL12A Human copper(0) increases expression ISO Il12a (Rattus norvegicus) 6480464 Copper results in increased expression of IL12A mRNA CTD PMID:30556269 IL12A Human crocidolite asbestos decreases expression EXP 6480464 Asbestos and Crocidolite results in decreased expression of IL12A mRNA CTD PMID:24160326 IL12A Human curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12A mRNA] CTD PMID:23452621 IL12A Human cyclophosphamide multiple interactions ISO Il12a (Mus musculus) 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] and ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12A protein] CTD PMID:29228376 and PMID:37853057 IL12A Human cyclophosphamide decreases expression ISO Il12a (Mus musculus) 6480464 Cyclophosphamide results in decreased expression of IL12A protein CTD PMID:37853057 IL12A Human cyclosporin A multiple interactions ISO Il12a (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:17312158 IL12A Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of IL12A mRNA CTD PMID:20106945 and PMID:25562108 IL12A Human daidzein multiple interactions ISO Il12a (Mus musculus) 6480464 daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:21945492 IL12A Human deoxynivalenol increases expression ISO Il12a (Mus musculus) 6480464 deoxynivalenol results in increased expression of IL12A mRNA CTD PMID:9707511 IL12A Human deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of IL12A mRNA CTD PMID:27757495 IL12A Human dexamethasone increases expression ISO Il12a (Mus musculus) 6480464 Dexamethasone results in increased expression of IL12A mRNA CTD PMID:22185406 IL12A Human dexamethasone multiple interactions ISO Il12a (Mus musculus) 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:22185406 IL12A Human dextran sulfate affects response to substance ISO Il12a (Mus musculus) 6480464 IL12A protein affects the susceptibility to Dextran Sulfate CTD PMID:12940437 IL12A Human diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of IL12A mRNA CTD PMID:34995734 IL12A Human diazinon increases methylation EXP 6480464 Diazinon results in increased methylation of IL12A gene CTD PMID:22964155 IL12A Human dichlorine increases expression ISO Il12a (Mus musculus) 6480464 Chlorine results in increased expression of IL12A protein CTD PMID:23146759 IL12A Human diltiazem multiple interactions EXP 6480464 Diltiazem inhibits the reaction [[NFKB1 protein binds to RELA protein] which binds to IL12A promoter] more ... CTD PMID:15652234 IL12A Human diltiazem decreases expression EXP 6480464 Diltiazem results in decreased expression of IL12A mRNA CTD PMID:15652234 IL12A Human Dimaprit multiple interactions EXP 6480464 Dimaprit inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:11752121 and PMID:12364868 IL12A Human dioxygen multiple interactions EXP 6480464 3 more ... CTD PMID:23452621 IL12A Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of IL12A mRNA CTD PMID:17175027 and PMID:23452621 IL12A Human doxorubicin multiple interactions ISO Il12a (Mus musculus) 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:29228376 IL12A Human esketamine decreases expression EXP 6480464 Esketamine results in decreased expression of IL12A mRNA CTD PMID:38219984 IL12A Human estriol increases expression ISO Il12a (Mus musculus) 6480464 Estriol results in increased expression of IL12A mRNA CTD PMID:21317386 IL12A Human ethanol multiple interactions ISO Il12a (Mus musculus) 6480464 Ethanol inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:10798593 IL12A Human ethyl methanesulfonate decreases expression EXP 6480464 Ethyl Methanesulfonate results in decreased expression of IL12A mRNA CTD PMID:23649840 IL12A Human eugenol multiple interactions ISO Il12a (Mus musculus) 6480464 Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 IL12A Human famotidine multiple interactions EXP 6480464 Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121 and PMID:12364868 IL12A Human fumigaclavine C decreases expression ISO Il12a (Mus musculus) 6480464 fumigaclavine C results in decreased expression of IL12A mRNA CTD PMID:16023606 IL12A Human fumonisin B1 increases expression EXP 6480464 fumonisin B1 results in increased expression of IL12A mRNA CTD PMID:27757495 IL12A Human Ganoderic acid C2 multiple interactions ISO Il12a (Mus musculus) 6480464 ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12A protein] CTD PMID:37853057 IL12A Human genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of IL12A mRNA] CTD PMID:23452621 IL12A Human gentamycin decreases expression ISO Il12a (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of IL12A mRNA and Gentamicins results in decreased expression of IL12A protein CTD PMID:22061828 and PMID:25051504 IL12A Human glucuronoxylomannan multiple interactions EXP 6480464 glucuronoxylomannan results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:12864811 IL12A Human glycyrrhizinic acid multiple interactions ISO Il12a (Mus musculus) 6480464 [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein] and [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12A mRNA CTD PMID:11412311 IL12A Human helenalin multiple interactions EXP 6480464 helenalin inhibits the reaction [Drugs more ... CTD PMID:15894585 IL12A Human histamine multiple interactions EXP 6480464 [Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12A protein more ... CTD PMID:11752121 more ... IL12A Human histamine increases expression EXP 6480464 Histamine results in increased expression of IL12A protein CTD PMID:15843518 IL12A Human histamine decreases expression EXP 6480464 Histamine results in decreased expression of IL12A mRNA and Histamine results in decreased expression of IL12A protein CTD PMID:9819373 IL12A Human hydrogen peroxide multiple interactions ISO Il12a (Mus musculus) 6480464 Hydrogen Peroxide results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:16249388 IL12A Human Ibudilast multiple interactions ISO Il12a (Mus musculus) 6480464 ibudilast results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:14664469 IL12A Human Ibudilast decreases expression ISO Il12a (Mus musculus) 6480464 ibudilast results in decreased expression of IL12A mRNA CTD PMID:14664469 IL12A Human imiquimod multiple interactions ISO Il12a (Mus musculus) 6480464 [imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein] and Tetrachlorodibenzodioxin inhibits the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:21097750 IL12A Human imiquimod increases secretion ISO Il12a (Mus musculus) 6480464 Imiquimod results in increased secretion of IL12A protein CTD PMID:31093508 IL12A Human indole-3-methanol multiple interactions EXP 6480464 indole-3-carbinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] and indole-3-carbinol inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA] CTD PMID:27783115 IL12A Human indometacin multiple interactions ISO Il12a (Mus musculus) 6480464 Indomethacin results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:11703811 IL12A Human iron atom multiple interactions EXP 6480464 Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 IL12A Human iron dichloride increases expression EXP 6480464 ferrous chloride results in increased expression of IL12A mRNA CTD PMID:35984750 IL12A Human iron(0) multiple interactions EXP 6480464 Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 IL12A Human isocyanates increases expression EXP 6480464 Isocyanates analog results in increased expression of IL12A protein CTD PMID:19111005 IL12A Human isoniazide increases secretion EXP 6480464 Isoniazid results in increased secretion of IL12A protein CTD PMID:28444390 IL12A Human isoprenaline decreases expression ISO Il12a (Rattus norvegicus) 6480464 Isoproterenol results in decreased expression of IL12A protein CTD PMID:24286936 IL12A Human kainic acid affects response to substance ISO Il12a (Mus musculus) 6480464 IL12A protein affects the susceptibility to Kainic Acid CTD PMID:15474355 IL12A Human ketamine increases expression ISO Il12a (Rattus norvegicus) 6480464 Ketamine results in increased expression of IL12A mRNA CTD PMID:20080153 IL12A Human lead diacetate decreases expression ISO Il12a (Mus musculus) 6480464 lead acetate results in decreased expression of IL12A mRNA CTD PMID:21829687 IL12A Human lead(0) multiple interactions ISO Il12a (Mus musculus) 6480464 Lead results in increased expression of and results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:28973681 IL12A Human leukotriene D4 multiple interactions EXP 6480464 BAY u9773 inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:19118273 IL12A Human lipid As multiple interactions EXP 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16299289 IL12A Human lipid As increases expression EXP 6480464 Lipid A results in increased expression of IL12A mRNA CTD PMID:16299289 IL12A Human lipopolysaccharide increases secretion ISO Il12a (Mus musculus) 6480464 Lipopolysaccharides results in increased secretion of IL12A protein CTD PMID:32800949 IL12A Human lipopolysaccharide increases expression ISO Il12a (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of IL12A mRNA and Lipopolysaccharides results in increased expression of IL12A protein CTD PMID:10415056 more ... IL12A Human lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IL12A mRNA CTD PMID:12470611 more ... IL12A Human lipopolysaccharide multiple interactions EXP 6480464 2'-hydroxyflavanone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12A protein] more ... CTD PMID:10651989 more ... IL12A Human lipopolysaccharide multiple interactions ISO Il12a (Mus musculus) 6480464 2 more ... CTD PMID:10415056 more ... IL12A Human lipopolysaccharide increases secretion EXP 6480464 Lipopolysaccharides results in increased secretion of IL12A protein CTD PMID:32800949 IL12A Human lupane multiple interactions EXP 6480464 lupane results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:16388738 IL12A Human manganese atom increases expression EXP 6480464 Manganese results in increased expression of IL12A mRNA CTD PMID:17175027 IL12A Human manganese(0) increases expression EXP 6480464 Manganese results in increased expression of IL12A mRNA CTD PMID:17175027 IL12A Human manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of IL12A mRNA CTD PMID:17175027 IL12A Human manganese(II) chloride multiple interactions EXP 6480464 manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:28539244 IL12A Human manganese(II) chloride multiple interactions ISO Il12a (Mus musculus) 6480464 manganese chloride results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:28539244 IL12A Human mangiferin decreases expression ISO Il12a (Mus musculus) 6480464 mangiferin results in decreased expression of IL12A mRNA CTD PMID:15135318 IL12A Human mechlorethamine increases expression ISO Il12a (Rattus norvegicus) 6480464 Mechlorethamine results in increased expression of IL12A mRNA CTD PMID:26273949 IL12A Human melphalan increases expression EXP 6480464 Melphalan results in increased expression of IL12A mRNA CTD PMID:22363485 IL12A Human mercury dichloride multiple interactions ISO Il12a (Mus musculus) 6480464 Mercuric Chloride results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:21984480 IL12A Human metam multiple interactions ISO Il12a (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:15933225 IL12A Human methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of IL12A mRNA CTD PMID:22133036 IL12A Human methyl 3,4,5-trihydroxybenzoate multiple interactions ISO Il12a (Mus musculus) 6480464 methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 IL12A Human methyl isothiocyanate multiple interactions ISO Il12a (Mus musculus) 6480464 methyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:15933225 IL12A Human methyl methanesulfonate decreases expression EXP 6480464 Methyl Methanesulfonate results in decreased expression of IL12A mRNA CTD PMID:23649840 IL12A Human MK-2206 multiple interactions EXP 6480464 MK 2206 inhibits the reaction [RARRES2 protein results in increased secretion of [IL12A protein binds to IL12B protein]] and MK 2206 results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:34398343 IL12A Human montelukast multiple interactions EXP 6480464 montelukast inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:19118273 IL12A Human morphine multiple interactions ISO Il12a (Mus musculus) 6480464 Morphine affects the expression of [IL12A protein binds to IL12B protein] CTD PMID:16299287 IL12A Human muramyl dipeptide multiple interactions EXP 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16299289 and PMID:18490488 IL12A Human N-acetyl-L-cysteine multiple interactions ISO Il12a (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 IL12A Human N-nitrosodiethylamine multiple interactions ISO Il12a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL12A mRNA CTD PMID:18164116 IL12A Human N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] and Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12A protein] CTD PMID:11752121 and PMID:9819373 IL12A Human neocuproine multiple interactions ISO Il12a (Mus musculus) 6480464 neocuproine inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of IL12A protein] CTD PMID:23604539 IL12A Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of IL12A mRNA CTD PMID:30421605 IL12A Human niclosamide multiple interactions EXP 6480464 Niclosamide inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA] CTD PMID:26297436 IL12A Human nicotine multiple interactions ISO Il12a (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] more ... CTD PMID:21237301 IL12A Human nonanoic acid increases expression ISO Il12a (Mus musculus) 6480464 pelargonic acid results in increased expression of IL12A mRNA CTD PMID:18652873 IL12A Human Nutlin-3 multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of IL12A mRNA CTD PMID:38460933 IL12A Human o-anisidine increases expression EXP 6480464 2-anisidine results in increased expression of IL12A mRNA CTD PMID:28089782 IL12A Human ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of IL12A mRNA CTD PMID:30763683 IL12A Human ozone multiple interactions EXP 6480464 [Vehicle Emissions co-treated with Ozone] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:27058360 IL12A Human ozone increases expression ISO Il12a (Mus musculus) 6480464 Ozone results in increased expression of IL12A mRNA CTD PMID:27240593 IL12A Human paclitaxel multiple interactions ISO Il12a (Mus musculus) 6480464 CD14 protein affects the reaction [Paclitaxel results in increased expression of IL12A mRNA] more ... CTD PMID:11123339 IL12A Human paclitaxel increases expression ISO Il12a (Mus musculus) 6480464 Paclitaxel results in increased expression of IL12A mRNA CTD PMID:11123339 IL12A Human paracetamol multiple interactions ISO Il12a (Mus musculus) 6480464 [IL33 protein affects the susceptibility to Acetaminophen] which affects the expression of IL12A mRNA CTD PMID:33887374 IL12A Human paracetamol increases expression ISO Il12a (Mus musculus) 6480464 Acetaminophen results in increased expression of IL12A mRNA CTD PMID:33887374 IL12A Human PCB138 affects expression EXP 6480464 2 more ... CTD PMID:21703328 IL12A Human phorbol 12,13-dibutanoate increases expression EXP 6480464 Phorbol 12 and 13-Dibutyrate results in increased expression of IL12A mRNA CTD PMID:15516327 IL12A Human phorbol 13-acetate 12-myristate multiple interactions ISO Il12a (Mus musculus) 6480464 IL12A results in decreased susceptibility to [9 more ... CTD PMID:22359662 IL12A Human pirinixic acid decreases expression ISO Il12a (Mus musculus) 6480464 pirinixic acid results in decreased expression of IL12A protein CTD PMID:20131406 IL12A Human poly(I:C) multiple interactions EXP 6480464 6-formylindolo(3 more ... CTD PMID:27783115 and PMID:35688559 IL12A Human poly(I:C) increases expression EXP 6480464 Poly I-C results in increased expression of IL12A mRNA CTD PMID:27783115 IL12A Human polymyxin B2 multiple interactions ISO Il12a (Mus musculus) 6480464 Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:26882889 IL12A Human prednisone multiple interactions EXP 6480464 Prednisone results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:19584951 IL12A Human pristane affects response to substance ISO Il12a (Mus musculus) 6480464 IL12A protein affects the susceptibility to pristane CTD PMID:12911539 IL12A Human progesterone multiple interactions ISO Il12a (Mus musculus) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of IL12A mRNA CTD PMID:19693291 IL12A Human progesterone multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines more ... CTD PMID:20130130 IL12A Human prostaglandin E2 multiple interactions EXP 6480464 Dinoprostone inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:11369638 IL12A Human raloxifene decreases expression EXP 6480464 Raloxifene Hydrochloride results in decreased expression of IL12A mRNA CTD PMID:19429434 IL12A Human ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] and Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12A protein] CTD PMID:11752121 and PMID:9819373 IL12A Human resiquimod multiple interactions ISO Il12a (Mus musculus) 6480464 [resiquimod co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:15851485 IL12A Human resiquimod multiple interactions EXP 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:18490488 and PMID:35688559 IL12A Human resveratrol multiple interactions ISO Il12a (Mus musculus) 6480464 Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of IL12A mRNA] and Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL12A protein] CTD PMID:14996416 and PMID:30165701 IL12A Human resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IL12A mRNA] and resveratrol promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12B protein co-treated with IL12A protein]] CTD PMID:15135313 and PMID:23452621 IL12A Human ribavirin multiple interactions EXP 6480464 [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] and Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 IL12A Human Ro 41-5253 multiple interactions EXP 6480464 Ro 41-5253 inhibits the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:16872382 IL12A Human S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:35811015 IL12A Human SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased expression of IFNG protein] more ... CTD PMID:10952721 and PMID:15894585 IL12A Human SB 203580 multiple interactions ISO Il12a (Mus musculus) 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:11006016 IL12A Human silicon dioxide multiple interactions ISO Il12a (Mus musculus) 6480464 IL12A gene mutant form promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein] CTD PMID:12193738 IL12A Human silicon dioxide increases response to substance ISO Il12a (Mus musculus) 6480464 IL12A gene mutant form results in increased susceptibility to Silicon Dioxide CTD PMID:12193738 IL12A Human sirolimus multiple interactions ISO Il12a (Mus musculus) 6480464 Sirolimus inhibits the reaction [IL4 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:12531798 IL12A Human stattic multiple interactions EXP 6480464 stattic inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA] CTD PMID:26297436 IL12A Human sulfasalazine multiple interactions ISO Il12a (Mus musculus) 6480464 Sulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL12A protein]] CTD PMID:11529938 IL12A Human temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of IL12A mRNA CTD PMID:31758290 IL12A Human testosterone decreases expression ISO Il12a (Mus musculus) 6480464 Testosterone results in decreased expression of IL12A mRNA CTD PMID:19693291 IL12A Human testosterone multiple interactions ISO Il12a (Rattus norvegicus) 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of IL12A mRNA CTD PMID:26496021 IL12A Human testosterone increases expression ISO Il12a (Mus musculus) 6480464 Testosterone results in increased expression of IL12A mRNA CTD PMID:19693291 IL12A Human thalidomide multiple interactions EXP 6480464 Thalidomide results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:11788559 IL12A Human theophylline multiple interactions EXP 6480464 Theophylline results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:15569413 IL12A Human titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of IL12A mRNA CTD PMID:19695317 IL12A Human toluene decreases expression ISO Il12a (Mus musculus) 6480464 Toluene results in decreased expression of IL12A mRNA CTD PMID:22057034 IL12A Human toluene affects expression ISO Il12a (Mus musculus) 6480464 Toluene affects the expression of IL12A mRNA CTD PMID:21601613 IL12A Human trichloroethene increases expression ISO Il12a (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of IL12A mRNA CTD PMID:33387578 IL12A Human trichostatin A multiple interactions EXP 6480464 trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:12470611 IL12A Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of IL12A mRNA CTD PMID:12470611 IL12A Human Triptolide multiple interactions EXP 6480464 triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15663903 IL12A Human tunicamycin multiple interactions EXP 6480464 Tunicamycin inhibits the reaction [IL12A protein binds to IL12B protein] and Tunicamycin results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:10779781 IL12A Human tunicamycin decreases N-linked glycosylation EXP 6480464 Tunicamycin results in decreased N-linked glycosylation of IL12A protein CTD PMID:10779781 IL12A Human urethane multiple interactions ISO Il12a (Mus musculus) 6480464 Freund's Adjuvant promotes the reaction [Urethane results in decreased expression of IL12A mRNA] CTD PMID:12810352 IL12A Human warfarin increases expression ISO Il12a (Rattus norvegicus) 6480464 Warfarin results in increased expression of IL12A mRNA CTD PMID:22342526 IL12A Human wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [C5 protein results in decreased expression of [IL12A protein binds to IL12B protein]] more ... CTD PMID:16116186 IL12A Human zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of IL12A mRNA CTD PMID:36828454 IL12A Human zileuton multiple interactions EXP 6480464 zileuton inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:19118273
