Symbol: |
CXCL10 |
Name: |
C-X-C motif chemokine ligand 10 |
RGD ID: |
12109165 |
Description: |
ENCODES a protein that exhibits chemokine activity (ortholog); CXCR3 chemokine receptor binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cellular response to heat (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); Acute-On-Chronic Liver Failure (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN extracellular space (ortholog) |
Type: |
protein-coding
|
RefSeq Status: |
PROVISIONAL |
Previously known as: |
C-X-C motif chemokine 10; chemokine (C-X-C motif) ligand 10; CXC chemokine ligand 10; small-inducible cytokine B10 |
RGD Orthologs |
|
Alliance Orthologs |
|
More Info |
more info ...
|
More Info |
|
Latest Assembly: |
CanFam3.1 - Dog CanFam3.1 Assembly |
Position: |
Dog Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
CanFam3.1 | 32 | 598,406 - 599,925 (-) | NCBI | CanFam3.1 | CanFam3.1 | canFam3 | CanFam3.1 | CanFam3.1 Ensembl | 32 | 597,987 - 599,979 (-) | Ensembl | CanFam3.1 | | canFam3 | CanFam3.1 | Dog10K_Boxer_Tasha | 32 | 41,282,571 - 41,284,090 (+) | NCBI | | Dog10K_Boxer_Tasha | | | ROS_Cfam_1.0 | 32 | 623,230 - 624,745 (-) | NCBI | | ROS_Cfam_1.0 | | | ROS_Cfam_1.0 Ensembl | 32 | 622,462 - 624,803 (-) | Ensembl | | ROS_Cfam_1.0 Ensembl | | | UMICH_Zoey_3.1 | 32 | 622,982 - 624,501 (-) | NCBI | | UMICH_Zoey_3.1 | | | UNSW_CanFamBas_1.0 | 32 | 577,290 - 578,808 (-) | NCBI | | UNSW_CanFamBas_1.0 | | | UU_Cfam_GSD_1.0 | 32 | 39,590,894 - 39,592,413 (+) | NCBI | | UU_Cfam_GSD_1.0 | | |
|
JBrowse: |
View Region in Genome Browser (JBrowse)
|
Model |
|
Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway (IEA,ISS) | antimicrobial humoral immune response mediated by antimicrobial peptide (ISO) | antiviral innate immune response (IEA) | cellular response to heat (ISO) | cellular response to interleukin-17 (IEA) | cellular response to lipopolysaccharide (IBA,IEA) | cellular response to virus (IEA) | chemokine-mediated signaling pathway (IBA,IEA) | chemotaxis (IEA,ISS) | defense response (IEA) | defense response to virus (IEA) | endothelial cell activation (IEA) | G protein-coupled receptor signaling pathway (IEA,ISS) | immune response (IEA,ISO) | inflammatory response (IBA,IEA) | negative regulation of angiogenesis (IEA,ISO) | negative regulation of myoblast differentiation (IEA) | negative regulation of myoblast fusion (IEA) | neutrophil chemotaxis (IBA) | positive chemotaxis (IEA) | positive regulation of cell migration (ISO) | positive regulation of cell population proliferation (ISO) | positive regulation of leukocyte chemotaxis (ISO) | positive regulation of monocyte chemotaxis (IEA) | positive regulation of release of sequestered calcium ion into cytosol (IEA,ISS) | positive regulation of T cell migration (IEA) | regulation of apoptotic process (IEA) | regulation of cell population proliferation (IEA,ISS) | regulation of endothelial tube morphogenesis (IEA) | regulation of T cell chemotaxis (IEA) | response to auditory stimulus (ISO) | response to bacterium (IEA) | response to gamma radiation (ISO) | response to lipopolysaccharide (ISO) | response to vitamin D (ISO) | T cell chemotaxis (IEA) |
CXCL10 (Canis lupus familiaris - dog) |
Dog Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
CanFam3.1 | 32 | 598,406 - 599,925 (-) | NCBI | CanFam3.1 | CanFam3.1 | canFam3 | CanFam3.1 | CanFam3.1 Ensembl | 32 | 597,987 - 599,979 (-) | Ensembl | CanFam3.1 | | canFam3 | CanFam3.1 | Dog10K_Boxer_Tasha | 32 | 41,282,571 - 41,284,090 (+) | NCBI | | Dog10K_Boxer_Tasha | | | ROS_Cfam_1.0 | 32 | 623,230 - 624,745 (-) | NCBI | | ROS_Cfam_1.0 | | | ROS_Cfam_1.0 Ensembl | 32 | 622,462 - 624,803 (-) | Ensembl | | ROS_Cfam_1.0 Ensembl | | | UMICH_Zoey_3.1 | 32 | 622,982 - 624,501 (-) | NCBI | | UMICH_Zoey_3.1 | | | UNSW_CanFamBas_1.0 | 32 | 577,290 - 578,808 (-) | NCBI | | UNSW_CanFamBas_1.0 | | | UU_Cfam_GSD_1.0 | 32 | 39,590,894 - 39,592,413 (+) | NCBI | | UU_Cfam_GSD_1.0 | | |
|
CXCL10 (Homo sapiens - human) |
Human Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
GRCh38 | 4 | 76,021,118 - 76,023,497 (-) | NCBI | GRCh38 | GRCh38 | hg38 | GRCh38 | GRCh38.p14 Ensembl | 4 | 76,021,118 - 76,023,497 (-) | Ensembl | GRCh38 | | hg38 | GRCh38 | GRCh37 | 4 | 76,942,271 - 76,944,650 (-) | NCBI | GRCh37 | GRCh37 | hg19 | GRCh37 | Build 36 | 4 | 77,161,295 - 77,163,674 (-) | NCBI | NCBI36 | Build 36 | hg18 | NCBI36 | Build 34 | 4 | 77,299,451 - 77,301,829 | NCBI | | | | | Celera | 4 | 74,243,028 - 74,245,407 (-) | NCBI | | Celera | | | Cytogenetic Map | 4 | q21.1 | NCBI | | | | | HuRef | 4 | 72,694,720 - 72,697,139 (-) | NCBI | | HuRef | | | CHM1_1 | 4 | 76,918,847 - 76,921,265 (-) | NCBI | | CHM1_1 | | | T2T-CHM13v2.0 | 4 | 79,361,779 - 79,364,158 (-) | NCBI | | T2T-CHM13v2.0 | | |
|
Cxcl10 (Mus musculus - house mouse) |
Mouse Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
GRCm39 | 5 | 92,494,497 - 92,496,748 (-) | NCBI | GRCm39 | GRCm39 | mm39 | | GRCm39 Ensembl | 5 | 92,494,497 - 92,496,748 (-) | Ensembl | | GRCm39 Ensembl | | | GRCm38 | 5 | 92,346,638 - 92,348,889 (-) | NCBI | GRCm38 | GRCm38 | mm10 | GRCm38 | GRCm38.p6 Ensembl | 5 | 92,346,638 - 92,348,889 (-) | Ensembl | GRCm38 | | mm10 | GRCm38 | MGSCv37 | 5 | 92,775,667 - 92,777,880 (-) | NCBI | GRCm37 | MGSCv37 | mm9 | NCBIm37 | MGSCv36 | 5 | 93,421,841 - 93,424,054 (-) | NCBI | | MGSCv36 | mm8 | | Celera | 5 | 90,490,436 - 90,492,644 (-) | NCBI | | Celera | | | Cytogenetic Map | 5 | E2 | NCBI | | | | | cM Map | 5 | 46.57 | NCBI | | | | |
|
Cxcl10 (Rattus norvegicus - Norway rat) |
Rat Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
GRCr8 | 14 | 15,989,066 - 15,991,263 (+) | NCBI | | GRCr8 | | | mRatBN7.2 | 14 | 15,704,772 - 15,706,969 (+) | NCBI | mRatBN7.2 | mRatBN7.2 | | | mRatBN7.2 Ensembl | 14 | 15,704,758 - 15,706,975 (+) | Ensembl | | mRatBN7.2 Ensembl | | | UTH_Rnor_SHR_Utx | 14 | 15,712,934 - 15,715,131 (+) | NCBI | Rnor_SHR | UTH_Rnor_SHR_Utx | | | UTH_Rnor_SHRSP_BbbUtx_1.0 | 14 | 17,031,780 - 17,033,977 (+) | NCBI | Rnor_SHRSP | UTH_Rnor_SHRSP_BbbUtx_1.0 | | | UTH_Rnor_WKY_Bbb_1.0 | 14 | 15,727,209 - 15,729,406 (+) | NCBI | Rnor_WKY | UTH_Rnor_WKY_Bbb_1.0 | | | Rnor_6.0 | 14 | 17,210,733 - 17,212,930 (+) | NCBI | Rnor6.0 | Rnor_6.0 | rn6 | Rnor6.0 | Rnor_6.0 Ensembl | 14 | 17,210,733 - 17,212,930 (+) | Ensembl | Rnor6.0 | | rn6 | Rnor6.0 | Rnor_5.0 | 14 | 17,126,865 - 17,129,062 (+) | NCBI | Rnor5.0 | Rnor_5.0 | rn5 | Rnor5.0 | RGSC_v3.4 | 14 | 17,265,986 - 17,268,183 (+) | NCBI | RGSC3.4 | RGSC_v3.4 | rn4 | RGSC3.4 | RGSC_v3.1 | 14 | 17,265,985 - 17,268,183 (+) | NCBI | | | | | Celera | 14 | 15,099,217 - 15,101,414 (+) | NCBI | | Celera | | | RH 3.4 Map | 14 | 182.09 | RGD | | | | | Cytogenetic Map | 14 | p22 | NCBI | | | | |
|
Cxcl10 (Chinchilla lanigera - long-tailed chinchilla) |
Chinchilla Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
ChiLan1.0 Ensembl | NW_004955433 | 748,284 - 750,927 (-) | Ensembl | ChiLan1.0 | | | | ChiLan1.0 | NW_004955433 | 748,392 - 750,890 (-) | NCBI | ChiLan1.0 | ChiLan1.0 | | |
|
CXCL10 (Pan paniscus - bonobo/pygmy chimpanzee) |
Bonobo Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
NHGRI_mPanPan1-v2 | 3 | 54,049,643 - 54,052,033 (+) | NCBI | | NHGRI_mPanPan1-v2 | | | NHGRI_mPanPan1 | 4 | 54,239,397 - 54,241,786 (+) | NCBI | | NHGRI_mPanPan1 | | | Mhudiblu_PPA_v0 | 4 | 48,182,355 - 48,184,733 (+) | NCBI | Mhudiblu_PPA_v0 | Mhudiblu_PPA_v0 | panPan3 | | PanPan1.1 | 4 | 54,020,204 - 54,022,606 (+) | NCBI | panpan1.1 | PanPan1.1 | panPan2 | | PanPan1.1 Ensembl | 4 | 54,020,204 - 54,022,606 (+) | Ensembl | panpan1.1 | | panPan2 | |
|
Cxcl10 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
CXCL10 (Sus scrofa - pig) |
Pig Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
Sscrofa11.1 Ensembl | 8 | 71,693,339 - 71,695,948 (-) | Ensembl | Sscrofa11.1 | | susScr11 | Sscrofa11.1 | Sscrofa11.1 | 8 | 71,693,641 - 71,695,948 (-) | NCBI | Sscrofa11.1 | Sscrofa11.1 | susScr11 | Sscrofa11.1 | Sscrofa10.2 | 8 | 75,829,909 - 75,831,236 (-) | NCBI | Sscrofa10.2 | Sscrofa10.2 | susScr3 | | Sscrofa10.2 | 8 | 75,881,457 - 75,882,217 (-) | NCBI | Sscrofa10.2 | Sscrofa10.2 | susScr3 | |
|
CXCL10 (Chlorocebus sabaeus - green monkey) |
Green Monkey Assembly | Chr | Position (strand) | Source | Genome Browsers |
---|
JBrowse | NCBI | UCSC | Ensembl |
---|
ChlSab1.1 | 7 | 24,526,657 - 24,529,193 (-) | NCBI | ChlSab1.1 | ChlSab1.1 | chlSab2 | | ChlSab1.1 Ensembl | 7 | 24,526,680 - 24,529,130 (-) | Ensembl | ChlSab1.1 | ChlSab1.1 Ensembl | chlSab2 | | Vero_WHO_p1.0 | NW_023666037 | 2,868,983 - 2,871,422 (-) | NCBI | Vero_WHO_p1.0 | Vero_WHO_p1.0 | | |
|
Cxcl10 (Heterocephalus glaber - naked mole-rat) |
|
.
|
alimentary part of gastrointestinal system
| | | | | | | | | | | | | |
6
|
5
|
5
|
23
|
22
|
16
|
6
|
6
|
6
|
6
|
33
|
22
|
12
|
14
|
10
|
Ensembl Acc Id: |
ENSCAFT00000036612 ⟹ ENSCAFP00000032015 |
Type: |
CODING |
Position: |
Dog Assembly | Chr | Position (strand) | Source |
---|
CanFam3.1 Ensembl | 32 | 597,987 - 599,979 (-) | Ensembl |
|
Ensembl Acc Id: |
ENSCAFT00845052887 ⟹ ENSCAFP00845041528 |
Type: |
CODING |
Position: |
Dog Assembly | Chr | Position (strand) | Source |
---|
ROS_Cfam_1.0 Ensembl | 32 | 622,462 - 624,803 (-) | Ensembl |
|
RefSeq Acc Id: |
NM_001010949 ⟹ NP_001010949 |
RefSeq Status: |
PROVISIONAL |
Type: |
CODING |
Position: |
Dog Assembly | Chr | Position (strand) | Source |
---|
CanFam3.1 | 32 | 598,406 - 599,925 (-) | NCBI | Dog10K_Boxer_Tasha | 32 | 41,282,571 - 41,284,090 (+) | NCBI | ROS_Cfam_1.0 | 32 | 623,230 - 624,745 (-) | NCBI | UMICH_Zoey_3.1 | 32 | 622,982 - 624,501 (-) | NCBI | UNSW_CanFamBas_1.0 | 32 | 577,290 - 578,808 (-) | NCBI | UU_Cfam_GSD_1.0 | 32 | 39,590,894 - 39,592,413 (+) | NCBI |
|
Sequence: |
ATGAACCAAAGTGCTGTTCTTATTTTTTGTCTTATCTTTCTGACTCTGAATGGTACTCAAGGAATACCTCTCTCTAGAACTATACGCTGTACCTGTATCAAGATTAGTGATCAACCTGTAAATCTAAG GTCCTTAGAAAAAATTGAGATGATTCCTGCAAGTCCATCGTGTCCACATGTTGAGATCATTGCCACAATGAAAAAGAGTGGGGAGAAAAGATGTCTGAATCCAGAATCTAAGACCATCAAGAGTTTAG TGAAAGCAATTAGCAAGAAAAGGTCTAGAAGATCTCCTTGA
hide sequence
|
RefSeq Acc Id: |
NP_001010949 ⟸ NM_001010949 |
- Peptide Label: |
precursor |
- UniProtKB: |
Q5KSV9 (UniProtKB/Swiss-Prot), A0A8C0KEM9 (UniProtKB/TrEMBL) |
- Sequence: |
MNQSAVLIFCLIFLTLNGTQGIPLSRTIRCTCIKISDQPVNLRSLEKIEMIPASPSCPHVEIIATMKKSGEKRCLNPESKTIKSLVKAISKKRSRRSP
hide sequence
|
|
Ensembl Acc Id: |
ENSCAFP00000032015 ⟸ ENSCAFT00000036612 |
|
Ensembl Acc Id: |
ENSCAFP00845041528 ⟸ ENSCAFT00845052887 |
|
RGD ID: | 13688678 |
Promoter ID: | EPDNEW_C6746 |
Type: | single initiation site |
Name: | CXCL10_1 |
Description: | C-X-C motif chemokine ligand 10 |
SO ACC ID: | SO:0000170 |
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) |
Experiment Methods: | Single-end sequencing. |
Position: | Dog Assembly | Chr | Position (strand) | Source |
---|
CanFam3.1 | 32 | 599,986 - 600,046 | EPDNEW |
|
Date |
Current Symbol |
Current Name |
Previous Symbol |
Previous Name |
Description |
Reference |
Status |
2017-09-12 |
CXCL10 |
C-X-C motif chemokine ligand 10 |
|
chemokine (C-X-C motif) ligand 10 |
Symbol and/or name change |
5135510 |
APPROVED |
|
|